WO2022222197A1 - Multi-mode personalized monitoring method - Google Patents

Multi-mode personalized monitoring method Download PDF

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WO2022222197A1
WO2022222197A1 PCT/CN2021/092129 CN2021092129W WO2022222197A1 WO 2022222197 A1 WO2022222197 A1 WO 2022222197A1 CN 2021092129 W CN2021092129 W CN 2021092129W WO 2022222197 A1 WO2022222197 A1 WO 2022222197A1
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component
value
monitoring
function
variable
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PCT/CN2021/092129
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French (fr)
Chinese (zh)
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丁贤根
丁远彤
肖苑辉
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港湾之星健康生物(深圳)有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00Pattern recognition
    • G06F18/20Analysing
    • G06F18/24Classification techniques
    • G06F18/241Classification techniques relating to the classification model, e.g. parametric or non-parametric approaches
    • G06F18/2411Classification techniques relating to the classification model, e.g. parametric or non-parametric approaches based on the proximity to a decision surface, e.g. support vector machines
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/045Combinations of networks
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/08Learning methods

Definitions

  • the invention relates to the field of industrial technology and the field of biomedicine, in particular to the measurement and monitoring of medical data and industrial data, in particular to a monitoring method for data obtained by indirect, multi-modal measurement that cannot be directly measured.
  • the measurement of physical and chemical quantities includes direct measurement and indirect measurement.
  • Direct measurement can be accomplished by improving the precision and accuracy of measuring physical and chemical quantities themselves. Indirect measurement is limited to the individual attributes of the person being measured. In many cases, it is difficult to directly measure its physical and chemical quantities. Sometimes even if indirect physical and chemical quantities are measured, it is difficult to monitor and convert them into sufficient precision and accuracy. The error meets the required physical and chemical quantity data.
  • the inventor also proposes a "multi-mode personalized calibration method", which attempts to measure a plurality of individualized, low-difficulty monitoring factor values associated with the measurement monitoring value by decomposing the measurement monitoring value, or multiple values related to the measurement monitoring value.
  • the monitoring value is related to the monitoring factor value and the measurement monitoring value with low accuracy and difficulty.
  • the measurement data is obtained, and then the correction of the measurement monitoring value is obtained indirectly by monitoring these data. Value - a reliable measurement result.
  • the physical and chemical quantities (monitoring values) that need to be measured are often related to other physical and chemical quantities (monitoring factor values), and there may be a relatively obvious functional relationship.
  • introducing sensors of various modes to measure the corresponding physical and chemical quantities, designing corresponding calculation methods, and incorporating the respective measured data into the monitoring calculation will bring obvious effects to the monitoring values.
  • the object algorithm proposed by the present invention is to monitor the individual of the measurement object according to its historical data.
  • the proposed group algorithm is to monitor each other horizontally for several objects with the same measurement properties. This method has obvious advantages for the monitoring of monitoring values that are related to the environment and to the subdivision classification of objects.
  • the current industry status of the measurement industry is mainly based on direct measurement, indirect measurement is relatively rare, and the method of individualization, multi-mode and monitoring has not been found yet.
  • the current status is:
  • the proposed human blood glucose monitoring is to monitor the millimolar concentration per liter (mmol/L) of glucose content in human veins.
  • the commonly used methods include:
  • Invasive single-point method draw venous blood for glucose testing
  • Minimally invasive single-point method puncture the finger to take the capillary blood of the finger and monitor the glucose with a test strip
  • Minimally invasive continuous method continuous monitoring of glucose by inserting an indwelling enzyme electrode probe into the arm
  • Non-invasive continuous methods electrophoresis is used to measure glucose in tissue fluid on the skin, infrared method to measure glucose through skin, microwave method to measure subcutaneous glucose, and contact lens with microcircuit to measure glucose in tears, etc.
  • infrared method to measure glucose through skin
  • microwave method to measure subcutaneous glucose
  • contact lens with microcircuit to measure glucose in tears
  • Single-point measurement cannot solve the problem of monitoring blood sugar fluctuations. For patients with type 1 diabetes, because the rapid drop in blood sugar in a short time cannot be alarmed, it will bring the patient's life in danger. Furthermore, for patients with type 2 diabetes, a single point measurement cannot address the optimal management and treatment of diabetes. Both invasive monitoring and minimally invasive monitoring bring pain and inconvenience to patients.
  • the measurement data itself has no information that can monitor itself, and cannot monitor itself.
  • the interference factors also include some personalized content, and it is impossible to use the same standard to eliminate these personalized interference.
  • the purpose and intent of the present invention are:
  • the present invention designs an object algorithm algorithm to carry out personalized monitoring according to historical records and agreed truth values.
  • the present invention proposes a group algorithm algorithm to monitor itself according to the data of other objects.
  • the agreed truth value referred to in the present invention is not limited to being obtained by measuring equipment with a higher precision, but can also be obtained by artificial intelligence and deep learning.
  • monitoring functions referred to in the present invention are not limited to these functions and formulas listed in the present application, including other functions and formulas designed by mid-level designers in the industry based on this idea.
  • step numbers of the present invention do not exist in the order of the numbers.
  • the scope of application of the present invention may include monitoring of measurement data and monitoring of other data.
  • the present invention emphasizes that the types of monitoring values, the types of monitoring factor values, and the division of objects and groups listed in the present invention are all derived from this idea. Due to space limitations and the basic spirit of the invention, the application of the present invention cannot list the types and associations of these data information one by one. The types of information proposed in the invention application are not meant to limit the idea of the present invention.
  • energy saving can be achieved through multi-mode measurement, object algorithm and group algorithm.
  • Figure 1 is a schematic diagram of multi-mode personalized monitoring
  • FIG. 1 Schematic diagram of blood glucose monitoring
  • Figure 7 Cargo compartment reefer layout.
  • Embodiment 1 External monitoring method of human body glucose data
  • One of the application embodiments of the present invention is an artificial intelligence-oriented personalized management method for diabetes, which is a typical application example of the present invention.
  • this embodiment only the description of the method of the present invention is involved, and it is not regarded as a complete design of an actual system, nor is it a limitation of the present invention.
  • FIG. 1 Schematic diagram of multi-mode personalized monitoring
  • each monitored person is regarded as each object, and in each monitor, the monitored components are monitored by a laser Raman analyzer and an infrared light analyzer, and a PPG/ECG analyzer (PPG: English full name Photoplethysmography, referred to as PPG.
  • PPG English full name Photoplethysmography
  • ECG English full name of Electrocardiography, referred to as ECG
  • a series of algorithms in the patent application of the present invention are used to eliminate the background noise, thereby obtaining accurate in vitro blood glucose monitoring values.
  • the method of venous blood blood test is required to obtain the agreed true value in the early stage, which is used as calibration.
  • the object algorithm proposed by the present invention is used to calculate Subject-corrected value, that is, blood glucose monitoring results.
  • the artificial intelligence big data analysis of many objects in the group can finally eliminate the step of venous blood drawing for the monitors and relieve the pain of the monitors.
  • FIG. 1 Schematic diagram of blood glucose monitoring
  • 2001 is a laser Raman spectrometer, which is used to irradiate human skin through infrared laser (the wavelengths of 785nm, 830nm, 1063nm, etc. are selected here), and transmit it to a depth of about 1mm to produce Raman effect, according to The characteristic value and amplitude of the Raman spectral shift of glucose, monitor the glucose content, and finally calculate the glucose content in the venous blood by using a series of algorithms of the present invention, that is, the blood glucose value determined by the World Health Organization.
  • 2002 is an infrared light analyzer, which acts as an auxiliary blood glucose monitoring device to monitor another blood glucose monitoring component.
  • PPG/ECG analyzer PPG: English full name Photoplethysmography, referred to as PPG.
  • ECG English full name Electrocardiography, referred to as ECG
  • monitoring blood pressure and pulse information monitoring blood pressure and pulse information, as an extended component of the present invention, participating in a series of algorithms of the present invention , which further enables the precision and accuracy of blood glucose monitoring.
  • 2004 is the real-time unit of the multi-mode personalized monitoring method of the present invention.
  • 2005 is a venous blood analyzer, which is one of the source channels of the agreed truth value of the present invention.
  • 2006 is the monitoring channel for the agreed truth value. It should be noted here that it is not a real-time online monitoring, but is used in the big data accumulation stage of the present invention. Once the big data accumulation is completed, this step can be omitted.
  • the present invention divides the monitoring components into a fixed component and a variable component.
  • the fixed component is the inherent part of the blood sugar content contained in the human skin and its subcutaneous tissue, which does not depend on the amount that changes with the blood sugar fluctuation of the human body, and the variable component is sensitive to the fluctuation of the glucose content in the human vein blood vessels. amount of change.
  • the present invention in order to further correlate the blood sugar fluctuations caused by changes in the blood flow rate of the human body, the present invention also introduces a cardiovascular blood pressure and pulse PPG/ECG analyzer to monitor the real-time blood pressure and pulse of the human body, and use this as an extension component.
  • the monitoring data of the present invention adopts the cloud computing mode, and the blood glucose monitoring data of each monitoring object is stored in the cloud server, forming a group big data mode.
  • the human body glucose value is detected based on Raman scattering spectrum, that is, the monitoring value described in the present invention. Since in the circuit of the Raman laser, all glucose will be detected, including at least the content of all glucose in the epidermis, intradermal, interstitial fluid, capillaries, venous blood vessels, etc., and even other The glucose at the unknown site, therefore, the detected glucose value is the sum of these glucose contents. According to the WHO definition, only glucose in the veins is needed. To this end, we design to use the changes in blood pressure and blood lipids as monitoring factor components, and according to the fluctuations in blood pressure and blood lipids, separate the glucose component in the venous blood vessels from the total glucose value, which is proposed by the present invention.
  • Longitudinal multi-mode monitoring monitor the monitoring value based on the historical data and real-time data of the object to make it a correction value.
  • the present invention also proposes horizontal multi-modal monitoring - monitoring the monitoring of one's own objects based on other historical statistical data in the group value to make it a correction value.
  • PDV is a variable component, which comes from the laser Raman analyzer and the infrared light analyzer in Figure 2, and mainly includes the change value of blood sugar.
  • PDF is a fixed component, also from laser Raman analyzer and infrared light analyzer, mainly including background noise and basic blood sugar content.
  • PDE is the extended component, which comes from a PCG/ECG analyzer.
  • MIF is the subject correction value, that is, the blood glucose value of the monitoring result.
  • DTM 1 (t), DTM 2 (t) to DTM m (t) are the analyzed blood sugar components, including epidermal blood sugar, intradermal blood sugar, interstitial fluid blood sugar, capillary blood sugar, venous blood sugar, etc. .
  • FIG. 4 is a spectrogram obtained by Raman scattering monitoring of mixed substances, that is, the synthesis of Raman waves of all substances detected at the Raman laser detection point.
  • 4010 is the horizontal axis, which represents the displacement wave of Raman scattering
  • 4020 is the vertical axis, which represents the intensity of the Raman wave.
  • 4001 is the first peak with a displacement of 1003cm -1
  • 4002 is the second peak with a displacement of 1125cm -1
  • 4003 is the third peak with a displacement of 1450cm-1
  • these three peaks constitute the characteristics of glucose "fingerprint”.
  • Other waveforms are characteristic of mixed non-glucose substances.
  • the method of the present invention needs to separate the signal quantity of glucose from the Raman scattering wave of the mixed substance in FIG. 4 .
  • FIG. 5 is the Raman shift spectrum of pure glucose, which is also the signal quantity of glucose that needs to be separated from FIG. 4 in the present invention.
  • 5010 is the horizontal axis, representing the displacement wave of Raman scattering
  • 5020 is the vertical axis, representing the intensity of the Raman wave
  • the curve in the figure is the component of the glucose Raman displacement wave
  • 5001 is the epidermal blood glucose value DTM 1 (t)
  • 5002 is the intradermal blood glucose value DTM 2 (t)
  • 5003 is the interstitial fluid blood glucose value DTM 3 (t)
  • 5004 is the capillary blood glucose value DTM 4 (t)
  • 5005 is the venous blood glucose value DTM 5 (t).
  • the final object correction value MIF(t) DTM 5 (t).
  • Methods of multimodal personalized monitoring including:
  • the monitoring value of the decomposition object is one or more monitoring components, the monitoring components are monitored, and the monitoring components are decomposed including one or more variable components, zero or more fixed components, and zero or more extended components that exist a monitoring function with the monitoring values.
  • the object algorithm is performed according to the historical and current monitoring components for the object to obtain an object correction value whose agreed true value error with the object is less than the allowable error.
  • the sensor for measuring blood glucose includes the monitoring data of the laser Raman spectrum analyzer as the monitoring component.
  • the monitoring data of the infrared light analyzer can also be added as the monitoring component.
  • the present invention divides the monitoring components into a fixed component and a variable component.
  • the fixed component is the inherent part of the blood sugar content contained in the human skin and its subcutaneous tissue, which does not depend on the amount that changes with the blood sugar fluctuation of the human body, and the variable component is sensitive to the fluctuation of the glucose content in the human vein blood vessels. amount of change.
  • the present invention in order to further correlate the blood sugar fluctuations caused by changes in the blood flow rate of the human body, the present invention also introduces a cardiovascular blood pressure and pulse PPG/ECG analyzer to monitor the real-time blood pressure and pulse of the human body, and use this as an extension component.
  • the monitoring data of the present invention adopts the cloud computing mode, and the blood glucose monitoring data of each monitoring object is stored in the cloud server, forming a group big data mode.
  • the present invention includes, but is not limited to, the steps of decomposing the monitoring value, and specifically, the following or various local improvement measures can be adopted:
  • the variable component is a monitoring component of the monitoring value that changes with environmental changes or a monitoring component specified by a user, and the variable component is obtained by monitoring with a sensor.
  • the fixed component is a type of the monitoring component that can be separated in the monitoring value, and within a sampling period equal to the variable component, the rate of change of the fixed component is the same as that of the variable component.
  • the ratio of the rate of change of the components is small, for the optimal selection of the biological health category, the ratio of the rate of change is less than 0.20, and for the optimal selection of the industrial category, the ratio of the rate of change is less than 0.10, and, under this condition, the fixed component
  • monitoring is performed using sensors or statistical predictions.
  • the other choice of the fixed component is to use the background noise as the fixed component, for example, the background noise of a laser Raman analyzer and the background noise of an infrared light analyzer.
  • Another option for the fixed component is to use the minimum value of the monitored component as the fixed component.
  • the selection of the change rate ratio range depends on the actual characteristics of the system. In some systems with high monitoring accuracy, the change rate ratio range can be smaller, for example, 0.01.
  • step S2030 the extended component is obtained by using sensor monitoring, and the monitoring function of the extended component and the monitoring value exists in a monitoring function including:
  • the change of the monitoring value affects the extended component in one direction, that is, the extended component is a function argument of the monitoring value.
  • the extended component is used as an auxiliary monitoring of the monitoring value.
  • the change of the blood glucose value locally affects the change of the blood oxygen content.
  • the blood glucose function becomes one of the independent variables of the blood oxygen function.
  • the change of the monitoring value affects the extended component in both directions, that is, the extended component and the monitoring value are mutually independent variables, and at this time, the extended component is used as the auxiliary monitoring and adjustment of the monitoring value.
  • the laser Raman shift amplitude and the change of the infrared wavelength are functions of mutual influence, which can be regarded as independent variables that are functions of each other.
  • the change of the extended component affects the monitoring value in one direction, that is, the monitoring value is a function argument of the extended component, and at this time, the extended component is used as an auxiliary adjustment of the monitoring value.
  • the blood glucose value is the mmol/L of the glucose content in the blood of human venous blood vessels, so the change of the pulse is important to the instantaneous blood glucose level. The value is influential.
  • the PPG/ECG pulse function is used as an independent variable of the blood glucose function, so as to more accurately monitor the blood glucose value.
  • step S2040 the monitoring value and the monitoring component are continuously monitored according to different continuous time series and specific moments, and the intermediate data and result data are stored in the information base.
  • the cloud center will continuously collect various useful data of the object and store it in the database.
  • the present invention includes, but is not limited to, the processing steps of the monitoring function. Specifically, the following or various local improvement measures can be adopted:
  • step S3010 a monitoring function between the monitoring value and the object is established according to formula (3.1), and the monitoring value is decomposed according to formula (3.2) to monitor components, including the variable component, the fixed component and the extended component component, the monitoring function of the monitoring value and the component is established according to formula (3.3), the variable component set is established according to formula (3.4), the fixed component set is established according to formula (3.5), and the extended component set is established according to formula (3.6).
  • MI f 3.1 (PD) (3.1)
  • MI f 3.3 (PDV, PDF, PDE) (3.3)
  • f 3.1 is the monitoring function of the monitoring value and the object
  • f 3.3 is the monitoring function of the monitoring value and the component
  • MI is the monitoring value or monitoring value data set
  • PD is the object or Object data set
  • PDV is the variable component or variable number component set
  • PDF is the fixed component or fixed component set
  • PDE is the extended component or the set of extended components
  • PFV ⁇ is the set of all the components numbered ⁇ .
  • variable component data or an element of the variable component data set n is the total number of the variable components
  • p is the total number of the fixed components, is numbered as The extended component data of or an element of the extended component data set, where Indicates that the PDE is an empty set, which means that the fixed component is not included
  • is the total number of the extended components
  • the decomposition includes frequency domain decomposition from the perspective of monitoring convenience, and time domain decomposition from the perspective of continuous time.
  • f 3.3 is selected to be the glucose monitoring function of the 2001 laser Raman analyzer and the glucose monitoring function of the 2002 infrared light analyzer in FIG. 2, respectively, and the PPG/ECG analyzer monitoring function in 2003 is used as the extended component , in 2004 to do the decomposition of formula (3.4) to formula (3.6).
  • Step S3020 monitor the variable component according to the functional relationship between the variable component determined by the formula (3.7) and the output signal of the sensor, and establish a function set of the variable component according to the formula (3.8), Equation (3.9) is the output signal function of the sensor:
  • f 3.7 ⁇ is the function of the variable component numbered ⁇
  • F 3.8 is the function set of the variable component
  • f 3.9 ⁇ is the sensor function
  • n is the total number of functions of the variable component
  • PDV ⁇ is the variable component numbered ⁇
  • SS ⁇ is the signal output by the sensor numbered ⁇
  • S ⁇ is the sensor numbered ⁇ .
  • Step S3030 monitor the fixed component according to the functional relationship between the fixed component determined by the formula (3.10) and the output signal of the sensor or the statistical prediction, and establish the function of the fixed component according to the formula (3.11).
  • Set, formula (3.12) is the output signal function of the sensor or the statistical prediction:
  • f 3.10 ⁇ is the function of the fixed component numbered ⁇
  • F 3.11 is the function set of the fixed component
  • f 3.12 ⁇ is the output signal function of the sensor or the statistical prediction
  • p is the fixed component
  • PDF ⁇ is the fixed component numbered ⁇
  • SS ⁇ is the signal output by the sensor numbered ⁇ or the statistical prediction
  • S ⁇ is the sensor numbered ⁇ or the statistical prediction.
  • Step S3040 monitor the extended component according to the functional relationship between the extended component determined by the formula (3.13) and the output signal of the sensor, and establish a function set of the extended component according to the formula (3.14), the formula (3.15 ) is the output signal function of the sensor:
  • F 3.14 is the function set of the extended component
  • n is the total number of functions of the extended component
  • are all natural numbers
  • the present invention includes, but is not limited to, the processing steps of background noise. Specifically, the following or various local improvement measures can be adopted:
  • Step S4010 for the object with the background noise, calculate according to the following steps:
  • the background noise is set as the fixed component
  • MI f 4.1 (PDV, PDF, PDE, PDN) (4.1)
  • MI f 4.6 (SV, SE, t) (4.6)
  • f 4.1 is the monitoring function including background noise
  • f 4.2 is the function with the background noise as the fixed component
  • f 4.3 is the extended component function including background noise
  • f 4.4 is the variable component sensor function
  • f 4.5 is the function of the background noise
  • f 4.6 is the monitoring value function
  • PDN is the background noise
  • SE is the sensor output signal of the extended component
  • SV is the sensor output of the variable component signal
  • t is the time series.
  • the background noise is selected as the electrical background noise of the CCD array and the glucose signal unique to the object of in vitro glucose monitoring, including epidermis, subcutaneous tissue, interstitial fluid, etc. Glucose in venous blood vessels as defined by the International Health Organization.
  • the intermediate technicians in the industry can make a detailed combination according to their own understanding, and use a laser Raman analyzer or other monitoring equipment for combined monitoring.
  • Step S4020 according to the actual application, in the case of single-variable monitoring, and in the case that the range of the variable-component sensor satisfies the application, adopt one of the variable-component sensors, and in the case of the variable-component sensor In the case that the range does not satisfy the application, a plurality of the variable component sensors are used to extend the range.
  • Another preferred solution is to divide the blood glucose value based on 4.2 as the boundary. For example, if the blood glucose value is greater than 4.2, one section of monitoring is designed, and if the blood glucose value is less than or equal to 4.2, another section of monitoring is designed.
  • step S4030 according to the actual application, in the case of multi-variable monitoring, each variable adopts one sensor of the variable component.
  • the use of a laser Raman analyzer and an infrared light analyzer is such a design solution.
  • Step S4040 according to the actual application, if the output data of the variable component sensor satisfies the application, it is not necessary to use the extended component sensor, and in the case that the output data of the variable component sensor cannot meet the application Next, use more than one sensor of the extended component described above.
  • the present invention includes, but is not limited to, the object algorithm. Specifically, the following or multiple local improvement measures can be adopted:
  • step S5010 standard or higher-level measurement accuracy monitoring equipment is used to monitor and obtain the monitoring value of the object as the agreed true value, record the monitoring time, and set the agreed true value
  • Step S5020 Set an initial parameter set, and calculate the object correction value, and then calculate the agreed true value according to the step S5010, calculate the error, if the error falls within the allowable error, assign the initial parameter set to the personalized parameter set, if If the error is greater than the allowable error, the initial parameter set is modified to be the personalized parameter set, so that the error falls within the allowable error.
  • Step S5030 using the personalized parameter set, using the current monitoring component and algorithms including extended Kalman filter algorithm, Monte Carlo particle algorithm, modern Bayesian algorithm, and the personalized parameter set , calculate the object correction value.
  • T-test or Z-test was used to analyze errors to remove outliers.
  • the support vector machine SVM and the convolutional neural network CNN algorithm are used to classify the historical values.
  • Step S5040 based on the setting, using the historical monitoring component, according to the set time interval, execute the step S5020 at the time interval point, and execute the step S5030 outside the time interval point to establish
  • the personalized parameter set and the time series corresponding to the monitoring components are recorded in the information database, and a deep learning algorithm is used to calculate the monitoring components and the personalized parameters of the objects in the information database set and the time series, find out the personalized parameter set with high probability and demarcate the corresponding monitoring component as the optimization point, and the high probability includes the probability specified by the user or the probability is greater than 30%.
  • step S5050 based on the personalized parameter set of the optimization point obtained in the step S5040, the object correction value is calculated by adopting a support vector machine algorithm and a convolutional neural network algorithm.
  • a medical-grade blood glucose and blood lipid blood test measurement device is used to obtain the measured values of the individual's blood glucose and blood lipids and record the measurement time, which are used as the agreed true values.
  • the values and time series of blood glucose and blood lipid measured by the equipment to be calibrated are used to calculate the vertical synchronization correction value, and the error between the vertical synchronization correction value and the agreed true value is calculated and verified. If the error If it is greater than the allowable error, modify the parameter set and iteratively calculate until the error is less than the allowable error.
  • the agreed truth value can also be obtained by statistics of other individuals and artificial intelligence algorithms. At this time, it is not necessary to use higher-level medical equipment to measure and obtain.
  • the calibration function can select algorithms such as mathematical statistics algorithm, support vector machine SVM, convolutional neural network CNN, etc., with the error smaller than the allowable error as the goal, for example, the convolution kernel or related parameters are trained, which are all summarized and personalized feature set.
  • the present invention includes, but is not limited to, the group algorithm. Specifically, the following or multiple locally improved measures can be adopted:
  • Step S6010 for all the objects in the group, calculate the optimization point and the object correction value, and record them in the information database.
  • Step S6020 according to the objects in the information database, for the optimization point and the object correction value, establish more than one object classification, and calibrate the object classification of the object, the individual classification of the object classification
  • the ratio of the number to the total number of objects is greater than the number specified by the user or greater than 0.2, and is recorded in the information base.
  • Step S6030 according to the object classification, for the optimization point and the object correction value, according to the principle of minimum error, calculate the personalized feature set of the object classification, and record it in the information database.
  • Step S6040 Calculate the group correction value of the object according to the personalized feature set of the object classification.
  • Step S6050 for the self-object, calculate the object classification to which the calibration belongs, and calculate the object correction value and the group correction value of the object according to the personalized feature set of the object classification.
  • Step S6060 according to the personalized feature set of the object classification, for the newly added object, determine its object classification according to the calculation of the monitoring value of the object, and directly adopt the personalized feature set of the classification to include: said agreed truth value without performing the step of monitoring said agreed truth value.
  • the personalized feature set includes the parameters of the object algorithm, the parameters of the population algorithm, the classification, and the agreed truth value of the object.
  • the use of the algorithm between groups can further improve the calibration efficiency and reduce the error.
  • targeted calibration is performed. , in order to obtain better results.
  • a group classification model is established, and a personalized feature set for classification is established. For individuals newly entering the group, calculation is performed to be included in the classification, and rapid calibration is performed with the personalized feature set corresponding to the classification.
  • the present invention includes, but is not limited to, a differential object algorithm, specifically as follows:
  • Step S7010 Calculate the difference between the monitoring value of the object at the optimization point and the correction value of the object, and record the difference in the information database.
  • Step S7020 if the difference value of each of the optimization points is a constant difference value, for the object correction value of the subsequent time series, use the monitoring value to subtract the constant difference value to calculate the object correction value .
  • Step S7030 if the difference value of each optimization point is a function difference value, then for the object correction value of the subsequent time series, subtract the function difference value from the monitoring value to calculate the object correction value .
  • Step S7040 if the difference value of the optimization point of the time series is an alternating difference value between the constant difference value and the function difference value, subtract the alternating difference value from the monitoring value to calculate the object correction value.
  • step S7050 for the Raman spectrum monitoring method, the object is scanned twice or more with excitation light with a slight frequency offset to generate two or more Raman spectra, and according to the Raman scattering characteristic shift of the object, the two or more
  • the Raman scattering spectrum generated by scanning is calculated by differential convolution or linear regression to eliminate the interference of background noise caused by fluorescence, and the wavelength difference of the excitation light with the slight frequency offset is between 0.2 and 100 nm.
  • the differential object algorithm is used to further counteract the influence of background noise and improve the monitoring accuracy.
  • the present invention includes, but is not limited to, the personalized feature set. Specifically, the following or various local improvement measures can be adopted:
  • Step S8010 set a constraint condition that the error of the corrected value of the object is less than the allowable error, establish the personalized feature set according to formula (8.1), and calculate the personalized feature set:
  • f 8.1 is the personalized feature set function
  • PF is the personalized feature set
  • MI is the monitoring value or the monitoring value data set
  • MIF is the object correction value or the object correction value set
  • is the error
  • ⁇ E is the allowable error.
  • Step S8020 decompose the personalized feature set:
  • the personalization feature set is decomposed into more than one personalized feature set category
  • the personalized feature set category is decomposed into one or more personalized feature set category components.
  • f 8.2 is the category function of the personalized feature set
  • PFT is the category of the personalized feature set
  • the decomposition includes frequency domain decomposition from the perspective of convenient calculation, and also includes time domain decomposition from the perspective of continuous time.
  • Step S8030 monitoring the time domain value of the personalized feature set category:
  • f 8.3 is the personalized feature set category time domain function
  • t is the continuous time series.
  • Step S8040 monitor the specific moment value of the personalized feature set category:
  • f 8.3 is the time domain function of the personalized feature set category
  • T is the specific moment
  • PFT T is the specific moment value of the personalized feature set category at the specific moment.
  • Step S8050 monitor the time domain value of the category component of the personalized feature set:
  • the personalized feature set category is decomposed into more than one personalized feature set category component according to formula (8.5), and the personalized feature set category component and the continuous time series have the function determined by formula (8.6) relationship, monitor the time domain value of the category component of the personalized feature set according to formula (8.5):
  • PFT f 8.5 (PFT 1 , PFT 2 , . . . , PFT q ) (8.5)
  • f 8.5 is the category decomposition function of the personalized feature set
  • f 8.6 is the time domain function of the category component of the personalized feature set
  • PFT 1 , PFT 2 , ..., PFT q are the category components of the personalized feature set
  • q is the The total number of category components of the personalized feature set
  • is the category component number of the personalized feature set
  • q and ⁇ are both natural numbers
  • 1 ⁇ q, PFT ⁇ is the category component of the personalized feature set numbered ⁇
  • Step S8060 monitor the specific moment value of the category component of the personalized feature set:
  • the specific time value of the category component of the personalized feature set at the specific time has a functional relationship determined by the formula (8.7) with the continuous time series, and the category component of the personalized feature set is monitored according to the formula (8.7).
  • the specific moment value at a specific moment :
  • PFT ⁇ T is the specific time value of the category component of the personalized feature set at the specific time.
  • the parameters and variables in all the algorithm formulas and the collected time series are taken as the content of the personalized parameter set, and are listed in the database using standardized work for subsequent algorithm use, especially the deep learning algorithm.
  • the present invention includes, but is not limited to, the mathematical model of the personalized feature set. Specifically, the following or various local improvement measures can be adopted:
  • Step S9010 fuzzy optimization method
  • the monitoring value and the monitoring component are optimized to obtain the optimal value of the object under the optimized situation, specifically including:
  • Step S9011 create a set:
  • a monitoring value set is established with the monitoring value elements, which is recorded as MIset.
  • a monitoring component set is established with the monitoring components as elements, denoted as MI ⁇ set, where ⁇ is the number of the monitoring components.
  • the monitoring value set is decomposed into a variable value set and a fixed value set.
  • variable value set is decomposed into a variable component set, the variable value set is denoted as PDVset, the variable component set is denoted as PDV ⁇ set, and ⁇ is the number of the variable component.
  • the fixed value set is decomposed into a fixed component set, the fixed value set is referred to as PDFset, the fixed component set is referred to as PDF ⁇ set, and ⁇ is the number of the fixed component.
  • Decompose the extended value set as the extended component set denote the extended value set as PDEset, and denote the extended value component set as is the number of the extended component.
  • the component personalized feature set set is a personalized feature set component set
  • the personalized feature set set is recorded as PFTset
  • the personalized feature set component set is recorded as PFT ⁇ set
  • is the number of the individualized feature set component
  • the sets include fuzzy sets and non-fuzzy sets.
  • Step S9012 create a cut set:
  • the mapping relationship between the sets is established in turn, and the monitoring value set and the monitoring component set are used for sorting as the primary key to become an ordered set, and the first ⁇ is taken after positive sorting from large to small.
  • the elements are used as the ordered head cut set, and the first ⁇ elements are taken as the ordered tail cut set after reverse sorting from small to large, as follows:
  • MIset ⁇ (mi
  • MI ⁇ set ⁇ ⁇ mi ⁇
  • MIset ⁇ ⁇ mi
  • MI ⁇ set ⁇ ⁇ mi ⁇
  • MIset ⁇ , MI ⁇ set ⁇ , PDset ⁇ , PDVset ⁇ , PDV ⁇ set ⁇ , PDFset ⁇ , PDF ⁇ set ⁇ , PDEset ⁇ , PDE ⁇ set ⁇ , PFTset ⁇ , PFT ⁇ set ⁇ are the ordered heads Cut set, MIset ⁇ , MI ⁇ set ⁇ , PDset ⁇ , PDVset ⁇ , PDV ⁇ set ⁇ , PDFset ⁇ , PDF ⁇ set ⁇ , PDEset ⁇ , PDE ⁇ set ⁇ , PFTset ⁇ , PFT ⁇ set ⁇ are the ordering For the tail cut set, ⁇ and ⁇ are less than the number of elements in the respective sets, that is, the position of the cut set, which belongs to a natural number, ⁇ is the positive sorting number, and ⁇ is the reverse sorting number.
  • Step S9013 train the cutout:
  • Step S9014 search for optimization of the interception set:
  • the characteristic peaks of the laser Raman spectrum and the infrared light spectrum also adopt the interception operation, so as to enhance the monitoring effect.
  • Step S9020 establish a partial differential model:
  • MI′ 1 is the first derivative of the monitoring component numbered 1
  • MI′ m is the first order derivative of the monitoring component numbered m
  • PDV' ⁇ is the ⁇ th 1st derivative of the variable component that includes more than one associated with the MI ⁇
  • PDF' ⁇ is the ⁇ -th 1st derivative of the fixed component that includes zero or more of the fixed components associated with the MI ⁇ .
  • PDE' ⁇ is the ⁇ th 1st derivative of the extended component that includes zero or more associated with the MI ⁇ .
  • PFT' ⁇ is the ⁇ -th 1st derivative of the extended component that includes zero or more components associated with the MI ⁇ .
  • the monitoring component in function f 9.23 is also replaced by MI ⁇ in f 9.24 .
  • is the highest order of the monitored component derivative
  • is the highest order of the variable component derivative
  • is the highest order of the extended component derivative
  • ⁇ , ⁇ , ⁇ , and ⁇ are all natural numbers.
  • the intercept operation is also used for the characteristic peaks of the laser Raman spectrum and the infrared light spectrum, so as to enhance the monitoring effect.
  • Step S9030 extreme value optimization method
  • the method of taking extreme values of the independent variable and the dependent variable in the partial differential equation including formula (9.23) and formula (9.24), and obtaining any
  • the method of calculating the monitoring value and the monitoring component is obtained, and the optimal value and the worst value of the monitoring value and the monitoring component are obtained to obtain This gets the optimal value for the object.
  • the characteristic peaks of the laser Raman spectrum, the infrared light spectrum, and the instantaneous value of blood glucose monitoring are all optimized according to their extreme values.
  • step S9031 according to the information base being continuously updated over time, in timed or irregular conditions, multiple learning and training are implemented, and methods including T test and Z test are used to select the monitoring value and the said monitoring value.
  • T test and Z test are used to select the monitoring value and the said monitoring value.
  • the optimal value of the component and the abnormal value of the monitoring value and the worst value of the monitoring component are monitored, and the abnormal value is eliminated, thereby obtaining the abnormal value of the object.
  • Step S9040 probability optimization method:
  • the object monitoring value and the object extension component collected in different time periods are selected, the monitoring value and the monitoring component are calculated, and the monitoring value and the monitoring component are calculated as the maximum value and the
  • the probability calculation method including the Bayesian algorithm is used, and when the statistics of the monitoring value and the monitoring component are the maximum value and the minimum value, the adjustable object in the object is monitored. The probability that the value and the extension component of the adjustable object have similar values, and the high probability verification is verified.
  • Calibrating the adjustable object monitoring value and the adjustable object extension component in the object when the monitoring value and the monitoring component are maximum values are the optimized adjustable object monitoring value and the optimized adjustable object extension component
  • the adjustable object monitoring value and the adjustable object extension component in the object when the monitoring value and the monitoring component are minimum values are calibrated to be a degraded adjustable object monitoring value and a degraded adjustable object extension component.
  • the sensitivity of the laser Raman spectrometer is very high, it is affected by the monitoring environment (such as external light, the pollution level of the monitoring point, the movement state of the monitoring individual, etc.), resulting in continuous time series, monitoring
  • the obtained laser Raman spectrum has certain fluctuations, so the method of probability optimization is adopted to eliminate the interference factors.
  • Step S9050 neural network optimization method:
  • Step S9051 according to including the mathematical model, for the relational information records in the information base, using the information records as neurons, and establishing a connection function between the neurons with the calculation results including the mathematical model, forming A neural network with more than one layer.
  • Step S9052 according to the connection function, according to the effect of the optimized adjustable object monitoring value and the optimized adjustable object extended component on the monitored value and the monitored component, divide and establish an excitatory type, an inhibitory type, and an explosive type.
  • a platform-type linker function the linker function includes a constant-type weight coefficient and a function-type weight coefficient.
  • Step S9053 using deep learning algorithms, including supervised learning, unsupervised learning, and reinforcement learning algorithms, to optimize the connection sub-function.
  • step S9054 a support vector machine algorithm is used to classify and screen the monitoring value and the monitoring component, and screen out the optimized adjustable object monitoring value and the optimized adjustable object extended component.
  • Step S9055 using a convolutional neural network algorithm, for the condition of ignoring the association between the objects, implementing convolution, activation, pooling, full connection, and training the connection sub-function to filter out the monitoring including optimization. value and the monitored component.
  • step S9056 a cyclic neural network algorithm is used to establish an intra-layer correlation function under the condition that the objects need to be correlated, and the linker function is trained to screen out the monitoring value and the monitoring component including the optimization.
  • step S9057 a deep neural network algorithm is used to establish an inter-layer correlation function under the condition that the object, the monitoring value and the monitoring component between the layers of the neural network need to be correlated, and the connection is trained. sub-function to filter out the monitoring value and the monitoring component including optimization.
  • step S9058 a feedforward neural network algorithm is used to train the connection sub-function under the condition that each neuron is only connected to the neurons of the previous layer, so as to filter out the monitoring value including the optimized monitoring value and the Monitor quantities.
  • step S9059 a feedback neural network algorithm is used to train the connection sub-function under the condition that each neuron is only connected to the neuron of the next layer, so as to filter out the monitoring value including the optimized monitoring value and the monitoring value. weight.
  • the neural network optimization method is mainly applied in the calculation of the object algorithm, the group algorithm and the personalized feature set.
  • the object algorithm it can be used for the calibration of the historical data to the current data
  • the group algorithm it can be used for the calibration of other objects to its own object
  • the personalized feature set it can be used for the optimization of the personalized feature set .
  • Step S9060 reversible optimization method
  • the result information can reversibly reproduce the monitoring value and the monitoring component reaches the optimum or the specified value within its interval, and the reversible relationship between the monitoring components .
  • Step S9070 timing repetition method
  • the mathematical model and the reversible relationship calculate the timing time series value when the monitoring value and the monitoring component reach the optimal value or the specified value starting from the current moment, that is, starting from the current moment, after the timing time When the time of the sequence value is reached, the monitoring value and the monitoring component reach the optimal value or the specified value.
  • Step S9080 delay reproduction method:
  • the mathematical model when the timing time series value is less than the predetermined health assessment time domain value, calculate the required delay time difference, and add the delay time difference to the mathematical model.
  • the model is used to ensure that the monitoring value and the monitoring component reach the optimal value or the specified value at the time point of the predetermined health assessment time.
  • the present invention includes, but is not limited to, network processing steps. Specifically, the following or multiple local improvement measures can be adopted:
  • step SA110 a cloud center based on the Internet model is established, and all information monitored by the present invention, including all the groups, all the information of the objects, the intermediate calculation results, and the information base, are transmitted through the wide area network network in the form of cloud terminals, and all stored One or more cloud servers based on the Internet are used as one or more cloud centers, and cloud computing mode is adopted to manage, calculate and support the cloud terminal.
  • step SA120 one or more cloud centers are established in the blockchain mode to store, manage and support the information base and the aforementioned steps.
  • the users use anonymous records, and the information in the information base uses timestamped Chain structure, users access the information base through encryption and decryption communication, the information supports anti-tampering, and supports anti-repudiation, multi-center, and no-center modes.
  • a secure multi-party computing model is used to establish, manage and support more than one organization.
  • the content of the information base of the organization performs the agreed calculation, and the obtained calculation result is shared by the participating organizations.
  • the organization includes one or more of the cloud centers and manages one or more of the objects.
  • the secure multi-party computation includes: public key mechanisms, hybrid circuits, inadvertent transmission, secret sharing, privacy-preserving set intersection protocols, homomorphic encryption, zero-knowledge proofs, and methods without trusted centers to enhance information security and protection Object Privacy.
  • step SA140 the centralized learning mode is used to establish and train the model training when the object privacy protection is not emphasized, and the information database is stored in a cloud center.
  • step S9150 the federated learning mode is used to establish and train the model training when the privacy protection of the object needs to be emphasized.
  • the model training is performed between more than one stored cloud center, and the respective cloud centers do not exchange their respective cloud centers. information.
  • a local area network-based server is established to store and manage the support center, and all information including all groups and objects, intermediate calculation results, and the information base monitored by the present invention are transmitted through the local area network network in the form of network terminals, and all stored in the On the server of the local area network, in order to manage, calculate and support.
  • the single point is to monitor the steps of monitoring, storage, management, calculation and support of one of the objects, and all the information of the object monitored by the present invention, the intermediate calculation results, and the information base are all stored in the single point. storage, perform all steps.
  • the monitoring object is an individual, and a dedicated monitoring device that supports wireless movement is used.
  • the monitoring device is connected to the individual's smart phone, and then works with the cloud server of the public network.
  • the function fitting here includes arithmetic median, arithmetic mean, curve median, curve mean, least squares method, Gaussian method, neural network method, etc.
  • Embodiment 2 Monitoring method for energy saving of fan in cargo hold of container ship
  • the energy-saving control of the high-power fan in the cargo hold is a multi-input and multi-output control system, in which the input includes the ambient temperature, wind speed, and in-box settings of each refrigerated container stacked in the cargo hold.
  • the temperature, the overall wind field of the cargo hold, etc. the output control includes the frequency conversion speed regulation of all the cargo hold fans, the air duct air outlet damper, the cargo hold air inlet, the cargo hold air outlet, the refrigerated container control signal, etc.
  • the overall control index is to ensure that the refrigerated container is in the box Under the condition that the quality of the goods and the temperature in the box set by the user remain unchanged, the energy consumption of the fan in the cargo compartment is reduced as much as possible. According to the actual system operation data, using the multi-mode monitoring method of the present invention, the fan control can be more reasonable and stable, and the energy saving effect is as high as 58%.
  • FIG. 6 As shown in the number 6010 is the cargo hold, in which are stacked refrigerated containers (refrigerated containers), and in the refrigerated containers, the refrigerator has a closed-loop temperature control system, such as a PID regulator control temperature system.
  • a closed-loop temperature control system such as a PID regulator control temperature system.
  • signals including internal set temperature, supply air temperature, return air temperature, and external ambient temperature of the refrigerated container are obtained from the external interface of the refrigerated container through an external communication device, or these signals are obtained through a built-in communication circuit.
  • Signals which are output as indicated by number 6036 and input to the input of the system as negative feedback signals as indicated by number 6032, together with the system given signal as indicated by number 6031 and the AI given signal as indicated by number 6033 , form a complete feedback signal as shown in No. 6043, drive the fan control subsystem shown in No. 6020 to control the fan, and finally form a closed-loop control method in control theory as shown in No. 5035. That is to say, according to the collected data, the control function is generated as the closed-loop negative feedback data, and the fan or the fan and the gate are directly controlled.
  • the closed loop proposed here is for the process time from acquisition to control, and this time difference is relatively short, for example, less than 20 minutes. It should be noted that the 20 minutes here is just an example, this number can be longer or shorter depending on the size of the cabin.
  • FIG. 3 The control method associated with FIG. 6 , using the state-space control method with multiple inputs and multiple outputs as shown in FIG. 3 .
  • the numbers 7010 and 7020 are the vertical planes where the headers of the refrigerated containers stacked in a cargo hold on the ship are located respectively.
  • the headers of the refrigerated containers refer to the end of the refrigerated containers where the operation panel of the refrigerator is located.
  • the stacking of containers has a three-dimensional coordinate number, namely row number Bay, column number Row, layer number Tier, referred to as BRT coordinates.
  • the white squares indicated by numbers 7012 and 7022 are the positions of the bottom ballast tanks, and the gray squares indicated by numbers 7011 and 7021 are the headers of the refrigerated containers, where the air at the headers The temperature changes as the reefer container works.
  • C1 to C9 used in FIG. 5 to indicate that the continuous quantities vary from small to large, but this does not mean that the continuous quantities are only divided into 9 levels of C1 to C9.
  • the data of one frame picture refers to collecting once for a container in a cargo hold and storing it in the database of environmental data according to the BRT coordinates. And so on for other active containers, passive containers, or non-contained cargo.
  • the set monitoring value includes at least the position coordinates of the refrigerated container in the cargo hold, the ambient temperature, the wind speed, the set temperature in the container, the temperature of the air outlet, the temperature of the air supply outlet, the operating status of the fan in the cargo hold, and the overall energy consumption of the cargo hold.
  • the agreed truth value is selected as the historical record value, and the monitoring factor value is set as the control function of the fan in the cargo compartment and the overall energy consumption function of the cargo compartment.
  • the correlation functions are set as refrigerated container control function, cargo hold fan control function, cargo hold temperature control function, and cargo hold energy consumption function.
  • the set object is the brand and model of the reefer container, and the seed group is set, in which each cargo hold is a group, each ship is a group, and each route is a group.
  • each fan or the control of the damper on each fan is selected as the longitudinal correction value, and the space state equation group shown in Figure 2 is used as the correlation function and the control function.
  • each ship use each cargo hold as a group to perform a group algorithm.
  • Artificial intelligence algorithms are used for deep learning and labeling, and training is performed using, for example, convolutional neural network CNN algorithm, Bayesian Bayes algorithm, adversarial neural network GAN algorithm, firefly algorithm, and ant colony algorithm.
  • the optimized indicators include the minimum energy consumption of the fan, the least equipment action (for example, the minimum number of start and stop times, the minimum number of start and stop fans), the least disturbance to the internal temperature field, and the least disturbance to the air output data, and the actual control room.
  • the results are stored in the database according to time, and all relevant data such as ship route data, weather data, container loading and unloading data, and docked terminal data that can be obtained are input into the database.
  • Each ship uses data communication satellites to connect to the cloud big data center in real time, and uses blockchain and secure multi-party computing to protect the information of each ship and each cargo owner.

Abstract

A multi-mode personalized monitoring method, comprising: decomposing a monitoring value into a variable monitoring component and a fixed monitoring component; introducing an extended component to monitor the monitoring value and background noise; calculating the variable component, the fixed component, and the extended component by means of a correlation function and a personalized feature set; monitoring a conventional true value by means of historical and current monitoring data; and executing an object algorithm and a differential object algorithm to obtain an object correction value having an error between the correction value and the conventional true value of an object less than an allowable error. In addition, by means of historical monitoring data of a single object and a plurality of objects, the object algorithm and a group algorithm are employed to optimize the personalized feature set. Monitoring data of other objects are employed for further calculation to obtain a group correction value of the object. Modes such as a cloud network big data mode, a local area network mode, and a single point mode are further comprised, and the dilemma brought by measuring all individuals by means of one standard in the prior art is solved.

Description

多模个性化监测的方法Methods of Multimodal Personalized Monitoring 技术领域technical field
本发明涉及工业技术领域和生物医学领域,具体涉及医学数据和工业数据的测量监测,尤其是对于无法直接测量而通过间接地、多模式地测量获得的数据的监测方法。The invention relates to the field of industrial technology and the field of biomedicine, in particular to the measurement and monitoring of medical data and industrial data, in particular to a monitoring method for data obtained by indirect, multi-modal measurement that cannot be directly measured.
背景技术Background technique
理化量的测量包括直接测量和间接测量,直接测量可以通过提高测量理化量本身的精确度和准确度即可完成。而间接测量,限于被测量者的自身个性化属性,很多情况下直接测量其理化量是困难的,有时甚至即便测量到了间接理化量数据,也很难监测换算成具备足够精确度和准确度、误差符合要求的理化量数据。The measurement of physical and chemical quantities includes direct measurement and indirect measurement. Direct measurement can be accomplished by improving the precision and accuracy of measuring physical and chemical quantities themselves. Indirect measurement is limited to the individual attributes of the person being measured. In many cases, it is difficult to directly measure its physical and chemical quantities. Sometimes even if indirect physical and chemical quantities are measured, it is difficult to monitor and convert them into sufficient precision and accuracy. The error meets the required physical and chemical quantity data.
例如,对于人体静脉血液中葡萄糖含量的体外无创测量监测,对于远洋集装箱货船的货舱风机如何在满足舱内冷藏集装箱工作的条件下实现最优化节能控制时的理化量测量监测,风力发电机最优控制中对于风场的理化量测量监测等,在目前技术手段条件下,都是一个极其困难的课题。For example, for the in vitro non-invasive measurement and monitoring of glucose content in human venous blood, for the measurement and monitoring of physical and chemical quantities during optimal energy-saving control of how the cargo hold fans of ocean-going container cargo ships meet the conditions of working with refrigerated containers in the cabin, wind turbines are optimal The measurement and monitoring of the physical and chemical quantities of the wind field in the control is an extremely difficult subject under the current technical means.
对于间接测量,发明人同时提出“多模式个性化校准的方法”,试图测量通过分解测量监测值为多个与测量监测值有关联的个性化、低难度的监测因素值,或者多个与测量监测值有关联的监测因素值和低准确度、地难度的测量监测值,采用这样的多模式个性化的监测,获得测量数据,再通过对这些数据进行监测,从而间接获得测量监测值的修正值——可信的测量结果。For indirect measurement, the inventor also proposes a "multi-mode personalized calibration method", which attempts to measure a plurality of individualized, low-difficulty monitoring factor values associated with the measurement monitoring value by decomposing the measurement monitoring value, or multiple values related to the measurement monitoring value. The monitoring value is related to the monitoring factor value and the measurement monitoring value with low accuracy and difficulty. Using such multi-mode personalized monitoring, the measurement data is obtained, and then the correction of the measurement monitoring value is obtained indirectly by monitoring these data. Value - a reliable measurement result.
如何根据间接测量的数据,获得测量监测值的修正值这一可信测量结果,发明人研究发现,需要完成以下关键步骤:How to obtain the credible measurement result of the correction value of the measurement monitoring value based on the indirect measurement data, the inventor found that the following key steps need to be completed:
1、引入个性化监测1. Introduce personalized monitoring
1.1、间接测量往往包含了很多干扰因素,必须予以扣除,否则无法实现减小误差,得到可信测量结果。1.1. Indirect measurement often contains a lot of interference factors, which must be deducted, otherwise it is impossible to reduce errors and obtain reliable measurement results.
1.2、各个对象自身存在的对象个性化干扰因素又往往差异化很大,必须依据对象个性化做逐个计算和扣除。1.2. The interference factors of object personalization existing in each object are often very different, and must be calculated and deducted one by one according to the personalization of the object.
1.3、即便对于同一个对象,还往往由于它所处在的环境不同,造成的环境个性化干扰因素又有所不同,因此必须扣除这些基于环境的个性化干扰。1.3. Even for the same object, the environment-specific interference factors are often different due to the different environments it is in. Therefore, these environment-based personalized interferences must be deducted.
2、引入多模式监测2. Introduce multi-mode monitoring
在同一个测量对象中,需要测量的理化量(监测值)往往与其它的理化量(监测因素值)有关,有可能还存在较为明显的函数关系。此时,引入多种模式的传感器测量相应的理化量,设计相应的计算方法,把测量到的各自的数据纳入监测计算,会给监测值带来明显的功效。In the same measurement object, the physical and chemical quantities (monitoring values) that need to be measured are often related to other physical and chemical quantities (monitoring factor values), and there may be a relatively obvious functional relationship. At this time, introducing sensors of various modes to measure the corresponding physical and chemical quantities, designing corresponding calculation methods, and incorporating the respective measured data into the monitoring calculation will bring obvious effects to the monitoring values.
3、引入对象算法和群体算法3. Introduce object algorithm and group algorithm
本发明所提出的对象算法,就是针对测量对象的个体,依据它的历史数据进行监测。所提出的群体算法,就是针对具有相同测量属性的若干个对象,进行横向的互相监测。这种方法对于监测值与环境有关、并且与对象的细分分类有关的监测值的监测,具有明显的优势。The object algorithm proposed by the present invention is to monitor the individual of the measurement object according to its historical data. The proposed group algorithm is to monitor each other horizontally for several objects with the same measurement properties. This method has obvious advantages for the monitoring of monitoring values that are related to the environment and to the subdivision classification of objects.
依据发明人的从业经验,发现目前的测量行业的业内现状主要还是以直接测量为主, 间接测量较为少见,并且采用个性化、多模式和监测的方法,尚未发现。尤其是针对以下若干具体应用的测量和监测,其现状是:According to the inventor's practice experience, it is found that the current industry status of the measurement industry is mainly based on direct measurement, indirect measurement is relatively rare, and the method of individualization, multi-mode and monitoring has not been found yet. In particular, measurement and monitoring for the following specific applications, the current status is:
1、人体血糖监测监测现状1. Current status of human blood glucose monitoring
所提出的人体血糖监测,根据国际卫生组织的定义,是监测人体静脉血管中葡萄糖含量的每升毫摩尔浓度(mmol/L),目前常用的方法包括:The proposed human blood glucose monitoring, according to the definition of the International Health Organization, is to monitor the millimolar concentration per liter (mmol/L) of glucose content in human veins. The commonly used methods include:
有创单点方式:抽取静脉血化验葡萄糖Invasive single-point method: draw venous blood for glucose testing
微创单点方式:扎手指取手指毛细血管血用试纸检监测葡萄糖Minimally invasive single-point method: puncture the finger to take the capillary blood of the finger and monitor the glucose with a test strip
微创连续方式:在手臂上扎入留置的酶电极探针连续监测葡萄糖Minimally invasive continuous method: continuous monitoring of glucose by inserting an indwelling enzyme electrode probe into the arm
无创连续方式:采用电泳方法在皮肤上测量组织液中的葡萄糖、采用红外方法透过皮肤测量葡萄糖、采用微波方法测量皮下葡萄糖、采用带有微电路的隐形眼镜测量眼泪中的葡萄糖等。但是截至到本专利申请时为止,尚未发现获得医疗权威部门授权的产品。Non-invasive continuous methods: electrophoresis is used to measure glucose in tissue fluid on the skin, infrared method to measure glucose through skin, microwave method to measure subcutaneous glucose, and contact lens with microcircuit to measure glucose in tears, etc. However, as of the time of this patent application, no product authorized by the medical authority has been found.
单点测量无法解决血糖波动的监测问题,这对于1型糖尿病患者来说,由于血糖的短时间急速下降不能报警,从而带来患者的生命危险。此外,对于2型糖尿病患者,单点测量无法解决糖尿病的优化管理和治疗问题。无论是有创监测还是微创监测,都给患者带来痛苦和不便。Single-point measurement cannot solve the problem of monitoring blood sugar fluctuations. For patients with type 1 diabetes, because the rapid drop in blood sugar in a short time cannot be alarmed, it will bring the patient's life in danger. Furthermore, for patients with type 2 diabetes, a single point measurement cannot address the optimal management and treatment of diabetes. Both invasive monitoring and minimally invasive monitoring bring pain and inconvenience to patients.
2、货舱节能监测监测现状2. Status of monitoring and monitoring of energy conservation in cargo hold
现有的货舱没有发现有任何风机节能的系统,然而对于现在的远洋集装箱船舶,货舱风机的能耗动辄上百千瓦,对于装载能力在上千集装箱的船舶来说,每年消耗在货舱上的能源折合成油耗或者LNG天然气消耗,高达数十万美元至数百万美元,并且由于高油耗、高气耗还带来了硫污染和碳污染,因此,市场需要节能方案。There is no fan energy-saving system found in the existing cargo hold. However, for the current ocean-going container ships, the energy consumption of the fan in the cargo hold is often hundreds of kilowatts. Converted to fuel consumption or LNG natural gas consumption, it is as high as hundreds of thousands of dollars to millions of dollars, and due to high fuel consumption and high gas consumption, sulfur pollution and carbon pollution are also brought about. Therefore, the market needs energy-saving solutions.
现有方法不足Existing methods are insufficient
发明人认为,现有的监测算法存在以下不足:The inventor believes that the existing monitoring algorithms have the following shortcomings:
1、直接测量在一些应用场景中无法实现,需要间接测量。1. Direct measurement cannot be achieved in some application scenarios, and indirect measurement is required.
2、从测量原理上看,测量数据自身没有能够监测自身的信息,无法监测自身。2. From the perspective of measurement principle, the measurement data itself has no information that can monitor itself, and cannot monitor itself.
3、对于难以直接测量的间接单点测量数据本身包含着干扰因素,传统方法无法消除。3. The indirect single-point measurement data that is difficult to measure directly contains interference factors, which cannot be eliminated by traditional methods.
4、干扰因素中除了包括共性化内容,更多地包括了一些个性化的内容,无法实现采用同一个标准消除这些个性化的干扰。4. In addition to the common content, the interference factors also include some personalized content, and it is impossible to use the same standard to eliminate these personalized interference.
5、虽然有些测量无法准确实现,但是可以通过引入多模式的监测变量,以增加测量准确度,但是目前没有发现这样的办法。5. Although some measurements cannot be accurately realized, multi-mode monitoring variables can be introduced to increase the measurement accuracy, but no such method has been found so far.
6、在大数据的前提下,群体中的对象之间存在一些共性,可以通过这些共性实现互相监测,然而目前尚未发现这样的监测方法。6. Under the premise of big data, there are some commonalities among the objects in the group, and mutual monitoring can be realized through these commonalities, but no such monitoring method has been found so far.
现有监测方法中的以上若干不足,现实系统中是存在的,需要有妥善的间接测量及其监测办法解决这些问题。The above-mentioned deficiencies in the existing monitoring methods exist in the actual system, and proper indirect measurement and monitoring methods are needed to solve these problems.
发明内容及目的Content and purpose of the invention
发明人通过长期的观察、实验和研究,提出多模个性化监测的方法,本发明的目的和意图在于:Through long-term observation, experiment and research, the inventor proposes a method for multimodal personalized monitoring. The purpose and intent of the present invention are:
1、对于无法直接准确测量或者直接准确测量难度较大的测量项目,引入间接的多模的辅助监测测量数据,实现监测。1. For measurement items that cannot be directly and accurately measured or are difficult to directly and accurately measure, indirect multi-mode auxiliary monitoring measurement data is introduced to realize monitoring.
2、对于连续实时测量,本发明设计对象算法算法,依据历史记录和约定真值,进行个性化监测。2. For continuous real-time measurement, the present invention designs an object algorithm algorithm to carry out personalized monitoring according to historical records and agreed truth values.
3、对于由多个测量对象,本发明提出群体算法算法,依据其它对象的数据监测自身。3. For a plurality of measurement objects, the present invention proposes a group algorithm algorithm to monitor itself according to the data of other objects.
4、通过人工智能深度学习算法,对于后加入群体的对象,实现分类监测,减少对于约定真值的采集,实现简化监测。4. Through the artificial intelligence deep learning algorithm, for the objects that join the group later, the classification monitoring is realized, the collection of the agreed truth value is reduced, and the monitoring is simplified.
特别声明:Special statement:
1、本发明所指的约定真值,并不局限于通过高一精准度的测量设备所获得的,还可以通过人工智能及深度学习所得。1. The agreed truth value referred to in the present invention is not limited to being obtained by measuring equipment with a higher precision, but can also be obtained by artificial intelligence and deep learning.
2、本发明所指的监测函数,并非受限于本发明申请所罗列的这些函数和公式,包括业内中级设计人员依据这一思路所设计的其它函数和公式。2. The monitoring functions referred to in the present invention are not limited to these functions and formulas listed in the present application, including other functions and formulas designed by mid-level designers in the industry based on this idea.
3、本发明的步骤编号,除非另外说明,否则不以编号大小存在前后顺序。3. The step numbers of the present invention, unless otherwise specified, do not exist in the order of the numbers.
本发明的应用范围可以包括测量数据的监测和其它数据的监测。The scope of application of the present invention may include monitoring of measurement data and monitoring of other data.
本发明强调,本发明所列举的无论是监测值的种类,还是监测因素值的种类,还是对象和群体的划分,都是源于这种思路。限于篇幅和发明的基本精神,本发明申请无法一一罗列这些数据信息的种类及关联,发明申请中所提出的信息种类,不意味着是对于本发明思路的限制。The present invention emphasizes that the types of monitoring values, the types of monitoring factor values, and the division of objects and groups listed in the present invention are all derived from this idea. Due to space limitations and the basic spirit of the invention, the application of the present invention cannot list the types and associations of these data information one by one. The types of information proposed in the invention application are not meant to limit the idea of the present invention.
发明的有益效果Beneficial Effects of Invention
1、提供基于多模个性化监测的创新方法,能够实现发明类容及其发明目的,解决现有监测技术的不足。1. Provide an innovative method based on multi-mode personalized monitoring, which can realize the invention and its purpose, and solve the shortcomings of the existing monitoring technology.
2、提供具体的基于数学、统计学、人工智能深度学习等方法,快速高效地实现测量数据的监测,实现个性化的大数据资源共享。2. Provide specific methods based on mathematics, statistics, artificial intelligence and deep learning to quickly and efficiently monitor measurement data and realize personalized big data resource sharing.
3、针对类似于人体葡萄糖的体外连续监测,能够有效地进行监测,提高了处理准确度。3. For in vitro continuous monitoring similar to human glucose, it can effectively monitor and improve the processing accuracy.
4、针对类似于远洋船舶的货舱风机节能,能够通过多模式测量、对象算法和群体算法,实现节能。4. For the energy saving of cargo cabin fans similar to ocean-going ships, energy saving can be achieved through multi-mode measurement, object algorithm and group algorithm.
附图说明Description of drawings
图1多模个性化监测示意图;Figure 1 is a schematic diagram of multi-mode personalized monitoring;
图2血糖监测示意图;Figure 2 Schematic diagram of blood glucose monitoring;
图3监测函数图;Figure 3 monitoring function diagram;
图4混合物质拉曼光谱;Figure 4 Raman spectrum of mixed substances;
图5葡萄糖拉曼光谱;Fig. 5 Raman spectrum of glucose;
图6货舱风机节能监测方法;Figure 6. The energy-saving monitoring method of the cargo cabin fan;
图7货舱冷藏箱布局。Figure 7 Cargo compartment reefer layout.
具体实施方式Detailed ways
本发明的目的和意图是采用如下实施例的技术方案实现的:The purpose and intention of the present invention is to adopt the technical scheme of the following embodiment to realize:
实施例一、人体葡萄糖数据外部监测方法Embodiment 1. External monitoring method of human body glucose data
本发明的应用实施例之一是面向糖尿病的人工智能个性化管疗治疗的方法,这是本发 明的一个典型的应用示例。在本实施例中,只涉及本发明的方法的叙述,不作为一个实际系统的完整设计,也不是对于本发明的限定。One of the application embodiments of the present invention is an artificial intelligence-oriented personalized management method for diabetes, which is a typical application example of the present invention. In this embodiment, only the description of the method of the present invention is involved, and it is not regarded as a complete design of an actual system, nor is it a limitation of the present invention.
1、图示说明1. Illustration description
图1多模个性化监测示意图Figure 1 Schematic diagram of multi-mode personalized monitoring
从人体外部监测血糖值,是一个极其困难的事情。根据世卫组织(英文名称:World Health Organization,缩写WHO,中文简称世卫组织)统计,世界糖尿病患者占总人口约11.4%,而人体静脉中的葡萄糖含量(简称血糖)又是确诊糖尿病的金标准。目前,常规的血糖监测分有创、微创和无创方法,其中有创包括在医院抽取静脉血,采用生化酶方法监测血糖值。微创大多采用扎手指挤出指血用试纸监测和在胳膊上扎入一个无线传感器来监测。而无创法由于完全是不穿透皮肤的方法,限于监测技术的发展,目前尚未发现较为普及的案例。此外,上述方法大多为单点测量,无法实现连续血糖值的监测。It is extremely difficult to monitor blood glucose levels from outside the human body. According to the World Health Organization (English name: World Health Organization, abbreviated WHO, Chinese abbreviation WHO) statistics, the world's diabetes patients account for about 11.4% of the total population, and the glucose content in human veins (referred to as blood sugar) is the gold for the diagnosis of diabetes. standard. At present, conventional blood glucose monitoring is divided into invasive, minimally invasive and non-invasive methods, among which invasive methods include drawing venous blood in the hospital and using biochemical enzyme methods to monitor blood glucose levels. Most of the minimally invasive methods are monitored by sticking a finger to squeeze out the blood with a test strip and inserting a wireless sensor on the arm. The non-invasive method is limited to the development of monitoring technology because it does not penetrate the skin at all, and no more popular cases have been found so far. In addition, most of the above methods are single-point measurement, which cannot realize continuous blood glucose monitoring.
在图1中,把每个被监测者当做每一个对象,在每个监测者中,采用激光拉曼分析仪和红外光分析仪监测所述监测分量,并且采用PPG/ECG分析仪(PPG:英文全称Photoplethysmography,简称PPG。ECG:英文全称Electrocardiography,,简称ECG)作为检测扩展分量。把由于人体的生物多样性而带来的个性化的干扰作为背景噪声,采用本发明专利申请的一系列算法消除背景噪声,从而获得准确的体外血糖监测值。其中,作为本发明专利的初期阶段应用,前期需要采用静脉血抽血化验的方法获得约定真值,以此作为校准,依据历史的和当前的监测数据,采用本发明所提出的对象算法,计算对象修正值,即血糖监测结果。此外,还对群体中众多的对象(即监测者)的人工智能大数据分析,最终可以免除监测者做静脉血抽血这一步骤,减轻监测者的痛苦。In Fig. 1, each monitored person is regarded as each object, and in each monitor, the monitored components are monitored by a laser Raman analyzer and an infrared light analyzer, and a PPG/ECG analyzer (PPG: English full name Photoplethysmography, referred to as PPG. ECG: English full name of Electrocardiography, referred to as ECG) as the detection extension component. Taking the individualized interference caused by the biological diversity of the human body as background noise, a series of algorithms in the patent application of the present invention are used to eliminate the background noise, thereby obtaining accurate in vitro blood glucose monitoring values. Among them, as the application of the patent of the present invention in the early stage, the method of venous blood blood test is required to obtain the agreed true value in the early stage, which is used as calibration. According to the historical and current monitoring data, the object algorithm proposed by the present invention is used to calculate Subject-corrected value, that is, blood glucose monitoring results. In addition, the artificial intelligence big data analysis of many objects in the group (that is, the monitors) can finally eliminate the step of venous blood drawing for the monitors and relieve the pain of the monitors.
图2血糖监测示意图Figure 2 Schematic diagram of blood glucose monitoring
图2中,2001是激光拉曼光谱分析仪,用于通过红外激光(这里选择波长为785nm、830nm、1063nm等波段)对于人体皮肤照射,并透射到1mm左右的深度,产生拉曼效应,根据葡萄糖的拉曼光谱位移的特征值和幅度,监测葡萄糖的含量,采用本发明的一系列算法,最终计算出静脉血液中葡萄糖的含量,即世界卫生组织确定的血糖值。2002是红外光分析仪,它作为一个辅助的血糖监测设备,监测另外一个血糖的监测分量。2003是PPG/ECG分析仪(PPG:英文全称Photoplethysmography,简称PPG。ECG:英文全称Electrocardiography,,简称ECG),监测血压及脉搏信息,作为本发明的扩展分量,参与到本发明的一系列算法中,进一步使得血糖监测的精确度和准确度。2004是本发明的多模个性化监测方法的实时单元。2005是静脉血分析仪,是本发明的约定真值的来源渠道之一。2006是约定真值的监测渠道,这里需要注意的是,它并非是实时在线的监测,而是本发明在大数据积累阶段所用,一旦到大数据积累完成,这一步是可以省略的。In Figure 2, 2001 is a laser Raman spectrometer, which is used to irradiate human skin through infrared laser (the wavelengths of 785nm, 830nm, 1063nm, etc. are selected here), and transmit it to a depth of about 1mm to produce Raman effect, according to The characteristic value and amplitude of the Raman spectral shift of glucose, monitor the glucose content, and finally calculate the glucose content in the venous blood by using a series of algorithms of the present invention, that is, the blood glucose value determined by the World Health Organization. 2002 is an infrared light analyzer, which acts as an auxiliary blood glucose monitoring device to monitor another blood glucose monitoring component. 2003 is PPG/ECG analyzer (PPG: English full name Photoplethysmography, referred to as PPG. ECG: English full name Electrocardiography, referred to as ECG), monitoring blood pressure and pulse information, as an extended component of the present invention, participating in a series of algorithms of the present invention , which further enables the precision and accuracy of blood glucose monitoring. 2004 is the real-time unit of the multi-mode personalized monitoring method of the present invention. 2005 is a venous blood analyzer, which is one of the source channels of the agreed truth value of the present invention. 2006 is the monitoring channel for the agreed truth value. It should be noted here that it is not a real-time online monitoring, but is used in the big data accumulation stage of the present invention. Once the big data accumulation is completed, this step can be omitted.
选择体外监测血糖作为监测值,选择测量血糖的传感器包括激光拉曼光谱分析仪的监测数据作为监测分量,根据需要,作为一种优选项,还可以增加红外光分析仪监测数据作为第二个监测分量。其中,由于人体体外血糖监测极其困难,为了完成准确监测,本发明在监测分量中划分固定分量和可变分量。其中,固定分量为人体皮肤及其皮下组织所包含的血糖含量的固有部分,该部分不依赖与人体的血糖波动而变化的量值,可变分量为受人体静脉血管中葡萄糖含量的波动而敏感变化的量值。作为一种优选项,为了进一步关联由于人体血液流速变化而引起的血糖波动,本发明还引入了心血管方面的血压、脉搏的 PPG/ECG分析仪,监测人体的实时的血压脉搏,并以此作为扩展分量。Select in vitro monitoring of blood sugar as the monitoring value, and select the sensor for measuring blood sugar, including the monitoring data of the laser Raman spectrum analyzer as the monitoring component. According to needs, as a preference, the monitoring data of the infrared light analyzer can also be added as the second monitoring. weight. Among them, since it is extremely difficult to monitor blood glucose outside the human body, in order to complete the accurate monitoring, the present invention divides the monitoring components into a fixed component and a variable component. Among them, the fixed component is the inherent part of the blood sugar content contained in the human skin and its subcutaneous tissue, which does not depend on the amount that changes with the blood sugar fluctuation of the human body, and the variable component is sensitive to the fluctuation of the glucose content in the human vein blood vessels. amount of change. As a preferred option, in order to further correlate the blood sugar fluctuations caused by changes in the blood flow rate of the human body, the present invention also introduces a cardiovascular blood pressure and pulse PPG/ECG analyzer to monitor the real-time blood pressure and pulse of the human body, and use this as an extension component.
另外,作为校准和传感器标定措施,采用准确度更高的医用版的静脉血抽血化验的办法,获得血糖的约定真值。本发明的监测数据采用云计算模式,各个监测对象的血糖监测数据存储于云服务器中,构成群体大数据模式。In addition, as a calibration and sensor calibration measure, a more accurate medical version of the venous blood test method is used to obtain the agreed true value of blood sugar. The monitoring data of the present invention adopts the cloud computing mode, and the blood glucose monitoring data of each monitoring object is stored in the cloud server, forming a group big data mode.
在本实施例中,采用基于拉曼散射光谱探测人体葡萄糖值,亦即本发明所述的监测值。由于在拉曼激光的回路中,全部葡萄糖都将被探测到,至少包括表皮部位、皮内部位、组织间液部位、毛细血管部位、静脉血管部位等处的全部葡萄糖的含量,甚至还包括其它未知部位的葡萄糖,因此,探测到的葡萄糖值时这些葡萄糖含量的总和。而依据世卫组织的定义,只有静脉血管中的葡萄糖才是需要的。为此,我们设计通过血压的变化量和血脂的变化量作为监测因素分量,依据血压和血脂的波动,从葡萄糖总量值中,分离出静脉血管中的葡萄糖分量,这就是本发明所提出的纵向多模监测——依据对象的历史数据、即时数据来监测监测值使之成为修正值。此外,依据群体的大数据的统计,对于不同的肤色、人种、工作性质等具体情况,本发明还提出的横向多模监测——依据群体中其它的历史统计数据,来监测自身对象的监测值使之成为修正值。In this embodiment, the human body glucose value is detected based on Raman scattering spectrum, that is, the monitoring value described in the present invention. Since in the circuit of the Raman laser, all glucose will be detected, including at least the content of all glucose in the epidermis, intradermal, interstitial fluid, capillaries, venous blood vessels, etc., and even other The glucose at the unknown site, therefore, the detected glucose value is the sum of these glucose contents. According to the WHO definition, only glucose in the veins is needed. To this end, we design to use the changes in blood pressure and blood lipids as monitoring factor components, and according to the fluctuations in blood pressure and blood lipids, separate the glucose component in the venous blood vessels from the total glucose value, which is proposed by the present invention. Longitudinal multi-mode monitoring - monitor the monitoring value based on the historical data and real-time data of the object to make it a correction value. In addition, according to the statistics of the big data of the group, for the specific situations of different skin color, race, work nature, etc., the present invention also proposes horizontal multi-modal monitoring - monitoring the monitoring of one's own objects based on other historical statistical data in the group value to make it a correction value.
图3监测函数图Figure 3 Monitoring function diagram
依据状态方程的信号系统分析方法,本实施例如图3所示。其中,经过图1的解析,PDV是可变分量,它来自于图2中的激光拉曼分析仪和红外光分析仪,主要包含血糖的变化值。PDF是固定分量,也是来自于激光拉曼分析仪和红外光分析仪,主要包含背景噪声和基础的血糖含量。PDE是扩展分量,它来自于PCG/ECG分析仪。MIF是对象修正值,即监测结果的血糖值。DTM 1(t)、DTM 2(t)至DTM m(t)是解析出的血糖分量,包括表皮血糖值、皮内血糖值、组织间液血糖值、毛细血管血糖值、静脉血管血糖值等。 According to the signal system analysis method of the state equation, this embodiment is shown in FIG. 3 . Among them, after the analysis of Figure 1, PDV is a variable component, which comes from the laser Raman analyzer and the infrared light analyzer in Figure 2, and mainly includes the change value of blood sugar. PDF is a fixed component, also from laser Raman analyzer and infrared light analyzer, mainly including background noise and basic blood sugar content. PDE is the extended component, which comes from a PCG/ECG analyzer. MIF is the subject correction value, that is, the blood glucose value of the monitoring result. DTM 1 (t), DTM 2 (t) to DTM m (t) are the analyzed blood sugar components, including epidermal blood sugar, intradermal blood sugar, interstitial fluid blood sugar, capillary blood sugar, venous blood sugar, etc. .
图4混合物质拉曼光谱Figure 4 Raman Spectrum of Mixed Matter
图4是针对混合物质的拉曼散射监测所得到的光谱图,亦即拉曼激光探测点上全部探测到的物质的拉曼波的合成。其中,4010是横轴,表示拉曼散射的位移波,4020是纵轴,表示拉曼波的强度,图中曲线为拉曼激光探测点上全部探测到的物质的拉曼波的合成,其中,4001是位移量为1003cm ‐1的第一个波峰,4002是位移量1125cm ‐1的第二个波峰,4003是位移量1450cm ‐1的第三个波峰,这3个波峰构成了葡萄糖的特征“指纹”。其它的波形是混合的非葡萄糖物质的特征波。 FIG. 4 is a spectrogram obtained by Raman scattering monitoring of mixed substances, that is, the synthesis of Raman waves of all substances detected at the Raman laser detection point. Among them, 4010 is the horizontal axis, which represents the displacement wave of Raman scattering, and 4020 is the vertical axis, which represents the intensity of the Raman wave. , 4001 is the first peak with a displacement of 1003cm -1 , 4002 is the second peak with a displacement of 1125cm -1 , 4003 is the third peak with a displacement of 1450cm-1, these three peaks constitute the characteristics of glucose "fingerprint". Other waveforms are characteristic of mixed non-glucose substances.
本发明的方法需要从图4的混合物质拉曼散射波中,分离出葡萄糖的信号量。The method of the present invention needs to separate the signal quantity of glucose from the Raman scattering wave of the mixed substance in FIG. 4 .
图5葡萄糖拉曼位移光谱Fig.5 Raman shift spectrum of glucose
图5是单纯葡萄糖的拉曼位移光谱,也是本发明需要从图4中分离得到的葡萄糖的信号量。其中,5010是横轴,表示拉曼散射的位移波,5020是纵轴,表示拉曼波的强度,图中曲线为葡萄糖拉曼位移波的分量,5001是表皮血糖值DTM 1(t),5002是皮内血糖值DTM 2(t),5003是组织间液血糖值DTM 3(t),5004是毛细血管血糖值DTM 4(t),5005是静脉血管血糖值DTM 5(t)。依据这种分类,最终的对象修正值MIF(t)=DTM 5(t)。 FIG. 5 is the Raman shift spectrum of pure glucose, which is also the signal quantity of glucose that needs to be separated from FIG. 4 in the present invention. Among them, 5010 is the horizontal axis, representing the displacement wave of Raman scattering, 5020 is the vertical axis, representing the intensity of the Raman wave, the curve in the figure is the component of the glucose Raman displacement wave, 5001 is the epidermal blood glucose value DTM 1 (t), 5002 is the intradermal blood glucose value DTM 2 (t), 5003 is the interstitial fluid blood glucose value DTM 3 (t), 5004 is the capillary blood glucose value DTM 4 (t), and 5005 is the venous blood glucose value DTM 5 (t). According to this classification, the final object correction value MIF(t) = DTM 5 (t).
2、基础方案步骤2. Basic program steps
2.1:总体说明2.1: General description
多模个性化监测的方法,包括:Methods of multimodal personalized monitoring, including:
分解对象的监测值为一个以上监测分量,监测所述监测分量,分解所述监测分量包括一个以上可变分量和零个以上固定分量和与所述监测值存在监测函数的零个以上扩展分量。The monitoring value of the decomposition object is one or more monitoring components, the monitoring components are monitored, and the monitoring components are decomposed including one or more variable components, zero or more fixed components, and zero or more extended components that exist a monitoring function with the monitoring values.
依据针对所述对象的历史的和当前的所述监测分量执行对象算法,得到与所述对象的约定真值误差小于允许误差的对象修正值。The object algorithm is performed according to the historical and current monitoring components for the object to obtain an object correction value whose agreed true value error with the object is less than the allowable error.
建立由一个以上具有相同监测值的所述对象构成的群体,采用大数据训练个性化特征集,依据所述个性化特征集和其它对象修正自身对象的群体算法,得到群体修正值。Establishing a group consisting of more than one object with the same monitoring value, using big data to train a personalized feature set, and revising a group algorithm for own objects according to the personalized feature set and other objects, to obtain a group correction value.
选择体外监测血糖作为监测值,选择测量血糖的传感器包括激光拉曼光谱分析仪的监测数据作为监测分量,根据需要,作为一种优选项,还可以增加红外光分析仪监测数据作为监测分量。其中,由于人体体外血糖监测极其困难,为了完成准确监测,本发明在监测分量中划分固定分量和可变分量。其中,固定分量为人体皮肤及其皮下组织所包含的血糖含量的固有部分,该部分不依赖与人体的血糖波动而变化的量值,可变分量为受人体静脉血管中葡萄糖含量的波动而敏感变化的量值。作为一种优选项,为了进一步关联由于人体血液流速变化而引起的血糖波动,本发明还引入了心血管方面的血压、脉搏的PPG/ECG分析仪,监测人体的实时的血压脉搏,并以此作为扩展分量。In vitro monitoring of blood glucose is selected as the monitoring value, and the sensor for measuring blood glucose includes the monitoring data of the laser Raman spectrum analyzer as the monitoring component. According to needs, as a preference, the monitoring data of the infrared light analyzer can also be added as the monitoring component. Among them, since it is extremely difficult to monitor blood glucose outside the human body, in order to complete the accurate monitoring, the present invention divides the monitoring components into a fixed component and a variable component. Among them, the fixed component is the inherent part of the blood sugar content contained in the human skin and its subcutaneous tissue, which does not depend on the amount that changes with the blood sugar fluctuation of the human body, and the variable component is sensitive to the fluctuation of the glucose content in the human vein blood vessels. amount of change. As a preferred option, in order to further correlate the blood sugar fluctuations caused by changes in the blood flow rate of the human body, the present invention also introduces a cardiovascular blood pressure and pulse PPG/ECG analyzer to monitor the real-time blood pressure and pulse of the human body, and use this as an extension component.
另外,作为校准和传感器标定措施,采用准确度更高的医用版的静脉血抽血化验的办法,获得血糖的约定真值。本发明的监测数据采用云计算模式,各个监测对象的血糖监测数据存储于云服务器中,构成群体大数据模式。In addition, as a calibration and sensor calibration measure, a more accurate medical version of the venous blood test method is used to obtain the agreed true value of blood sugar. The monitoring data of the present invention adopts the cloud computing mode, and the blood glucose monitoring data of each monitoring object is stored in the cloud server, forming a group big data mode.
2.2:分解监测值2.2: Decomposing monitoring values
在前述技术方案的基础上,本发明包括但不限于分解监测值的步骤,具体可以采用如下列的或者多种局部改进的措施:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, the steps of decomposing the monitoring value, and specifically, the following or various local improvement measures can be adopted:
S2010步骤,所述可变分量为所述监测值中随着环境变化而变化的监测分量或用户指定的监测分量,所述可变分量采用传感器监测获得。In step S2010, the variable component is a monitoring component of the monitoring value that changes with environmental changes or a monitoring component specified by a user, and the variable component is obtained by monitoring with a sensor.
S2020步骤,所述固定分量是一类在所述监测值中能够分离的所述监测分量,并且在同等于所述可变分量的采样周期内,所述固定分量的变化率与所述可变分量的变化率比值较小,对于生物健康类的优化选择,所述变化率比值小于0.20,对于工业类的优化选择,所述变化率比值小于0.10,并且,在此条件下,所述固定分量依据所述用户选择,采用传感器或统计预测来监测。In step S2020, the fixed component is a type of the monitoring component that can be separated in the monitoring value, and within a sampling period equal to the variable component, the rate of change of the fixed component is the same as that of the variable component. The ratio of the rate of change of the components is small, for the optimal selection of the biological health category, the ratio of the rate of change is less than 0.20, and for the optimal selection of the industrial category, the ratio of the rate of change is less than 0.10, and, under this condition, the fixed component Depending on the user selection, monitoring is performed using sensors or statistical predictions.
在本实施例中,固定分量的其它选择是将背景噪声作为固定分量,例如激光拉曼分析仪的背景噪声、红外光分析仪的背景噪声。固定分量的其它选择还可以是将监测分量的最小值作为固定分量。变化率比值范围的选择,根据系统的实际特征而定,在一些监测精度较高的系统中,变化率比值范围可以更小,例如0.01。In this embodiment, the other choice of the fixed component is to use the background noise as the fixed component, for example, the background noise of a laser Raman analyzer and the background noise of an infrared light analyzer. Another option for the fixed component is to use the minimum value of the monitored component as the fixed component. The selection of the change rate ratio range depends on the actual characteristics of the system. In some systems with high monitoring accuracy, the change rate ratio range can be smaller, for example, 0.01.
S2030步骤,所述扩展分量采用传感器监测获得,所述扩展分量与所述监测值存在监测函数的所述监测函数包括:In step S2030, the extended component is obtained by using sensor monitoring, and the monitoring function of the extended component and the monitoring value exists in a monitoring function including:
所述监测值的变化单方向影响所述扩展分量,即所述扩展分量是所述监测值的函数自变量,此时采用所述扩展分量作为所述监测值的辅助监测。The change of the monitoring value affects the extended component in one direction, that is, the extended component is a function argument of the monitoring value. In this case, the extended component is used as an auxiliary monitoring of the monitoring value.
在另外的实施例中,血糖值的变化局部影响血氧含量的变化,这种情况下,血糖函数就成为了血氧函数的自变量之一。In another embodiment, the change of the blood glucose value locally affects the change of the blood oxygen content. In this case, the blood glucose function becomes one of the independent variables of the blood oxygen function.
所述监测值的变化双方向影响所述扩展分量,即所述扩展分量与所述监测值是互为函 数自变量,此时采用所述扩展分量作为所述监测值的辅助监测和调节。The change of the monitoring value affects the extended component in both directions, that is, the extended component and the monitoring value are mutually independent variables, and at this time, the extended component is used as the auxiliary monitoring and adjustment of the monitoring value.
在本实施例中,激光拉曼位移幅度与红外波长的变化之间就是相互影响的函数,可视作互为函数的自变量。In this embodiment, the laser Raman shift amplitude and the change of the infrared wavelength are functions of mutual influence, which can be regarded as independent variables that are functions of each other.
所述扩展分量的变化单方向影响所述监测值,即所述监测值是所述扩展分量的函数自变量,此时采用所述扩展分量作为所述监测值的辅助调节。The change of the extended component affects the monitoring value in one direction, that is, the monitoring value is a function argument of the extended component, and at this time, the extended component is used as an auxiliary adjustment of the monitoring value.
例如,当采用PPG/ECG分析仪作为扩展分量传感时,由于根据国际卫生组织的定义,血糖值是人体静脉血管中血液中的葡萄糖的含量的mmol/L,所以,脉搏的变化对于瞬时血糖值是有影响的,本实施例将PPG/ECG脉搏函数作为血糖函数的自变量,以更加精准地实现血糖值的监测。For example, when a PPG/ECG analyzer is used as extended component sensing, since according to the definition of the International Health Organization, the blood glucose value is the mmol/L of the glucose content in the blood of human venous blood vessels, so the change of the pulse is important to the instantaneous blood glucose level. The value is influential. In this embodiment, the PPG/ECG pulse function is used as an independent variable of the blood glucose function, so as to more accurately monitor the blood glucose value.
S2040步骤,依据不同的连续时间序列和特定时刻,持续监测所述监测值和所述监测分量,将中间数据和结果数据存储到信息库。In step S2040, the monitoring value and the monitoring component are continuously monitored according to different continuous time series and specific moments, and the intermediate data and result data are stored in the information base.
在本实施例中,云中心将持续收集对象的各种有用数据,存储到数据库中。In this embodiment, the cloud center will continuously collect various useful data of the object and store it in the database.
2.3:监测函数2.3: Monitoring functions
在前述技术方案的基础上,本发明包括但不限于监测函数的处理步骤,具体可以采用如下列的或者多种局部改进的措施:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, the processing steps of the monitoring function. Specifically, the following or various local improvement measures can be adopted:
S3010步骤,按照公式(3.1)建立所述监测值与所述对象的监测函数,按照公式(3.2)分解所述监测值为监测分量,包括所述可变分量、所述固定分量和所述扩展分量,按照公式(3.3)建立所述监测值与分量的监测函数,按照公式(3.4)建立可变分量集合,按照公式(3.5)建立固定分量集合,按照公式(3.6)建立扩展分量集合。In step S3010, a monitoring function between the monitoring value and the object is established according to formula (3.1), and the monitoring value is decomposed according to formula (3.2) to monitor components, including the variable component, the fixed component and the extended component component, the monitoring function of the monitoring value and the component is established according to formula (3.3), the variable component set is established according to formula (3.4), the fixed component set is established according to formula (3.5), and the extended component set is established according to formula (3.6).
MI=f 3.1(PD)             (3.1) MI = f 3.1 (PD) (3.1)
PD=PDV∪PDF∪PDE                (3.2)PD=PDV∪PDF∪PDE (3.2)
MI=f 3.3(PDV,PDF,PDE)                (3.3) MI=f 3.3 (PDV, PDF, PDE) (3.3)
PDV={PDV β|PDV β编号β的可变分量数据,1≤β≤n}        (3.4) PDV={PDV β | PDV β number β variable component data, 1≤β≤n} (3.4)
PDF={PDF γ|PDF γ编号γ的固定分量数据,0≤γ≤p}        (3.5) PDF = {PDF γ | PDF γ fixed component data of number γ, 0≤γ≤p} (3.5)
Figure PCTCN2021092129-appb-000001
Figure PCTCN2021092129-appb-000001
其中,f 3.1为所述监测值与所述对象的所述监测函数,f 3.3为所述监测值与分量的所述监测函数,MI为所述监测值或监测值数据集合,PD为对象或对象数据集合,PDV为所述可变分量或可变数分量集合,PDF为所述固定分量或固定分量集合,PDE为所述扩展分量或所述扩展分量的集合,PFV β为编号为β的所述可变分量数据或所述可变分量数据集合的元素,n为所述可变分量的总数,PDV γ为编号为γ的固定分量数据或所述固定分量数据集合的元素,其中γ=0表示PDF为空集,指不包含所述固定分量,p为所述固定分量的总数,
Figure PCTCN2021092129-appb-000002
为编号为
Figure PCTCN2021092129-appb-000003
的扩展分量数据或所述扩展分量数据集合的元素,其中
Figure PCTCN2021092129-appb-000004
表示PDE为空集,指不包含所述固定分量,φ为所述扩展分量的总数,所述分解包括从便于监测角度的频域分解,还包括从连续时间角度的时域分解。
Wherein, f 3.1 is the monitoring function of the monitoring value and the object, f 3.3 is the monitoring function of the monitoring value and the component, MI is the monitoring value or monitoring value data set, PD is the object or Object data set, PDV is the variable component or variable number component set, PDF is the fixed component or fixed component set, PDE is the extended component or the set of extended components, PFV β is the set of all the components numbered β. the variable component data or an element of the variable component data set, n is the total number of the variable components, PDV γ is the fixed component data numbered γ or an element of the fixed component data set, where γ=0 Indicates that the PDF is an empty set, which does not contain the fixed components, p is the total number of the fixed components,
Figure PCTCN2021092129-appb-000002
is numbered as
Figure PCTCN2021092129-appb-000003
The extended component data of or an element of the extended component data set, where
Figure PCTCN2021092129-appb-000004
Indicates that the PDE is an empty set, which means that the fixed component is not included, φ is the total number of the extended components, and the decomposition includes frequency domain decomposition from the perspective of monitoring convenience, and time domain decomposition from the perspective of continuous time.
在本实施例中,选择f 3.3分别为图2中的2001激光拉曼分析仪的葡萄糖监测函数和2002红外光分析仪的葡萄糖监测函数,以2003中的PPG/ECG分析仪监测函数作为扩展分量,在2004中做公式(3.4)至公式(3.6)的分解运算。 In this embodiment, f 3.3 is selected to be the glucose monitoring function of the 2001 laser Raman analyzer and the glucose monitoring function of the 2002 infrared light analyzer in FIG. 2, respectively, and the PPG/ECG analyzer monitoring function in 2003 is used as the extended component , in 2004 to do the decomposition of formula (3.4) to formula (3.6).
由于激光拉曼分析仪、红外光分析仪和PPG/ECG分析仪均为数字化采样方式监测数据的,其变量的下标标识采样时刻,下同。Since laser Raman analyzers, infrared light analyzers, and PPG/ECG analyzers all use digital sampling to monitor data, the subscripts of their variables identify the sampling time, the same below.
S3020步骤,按照公式(3.7)确定的所述可变分量和所述传感器的输出信号之间的函数关系,监测所述可变分量,按照公式(3.8)建立所述可变分量的函数集合,公式(3.9)是所述传感器的输出信号函数:Step S3020, monitor the variable component according to the functional relationship between the variable component determined by the formula (3.7) and the output signal of the sensor, and establish a function set of the variable component according to the formula (3.8), Equation (3.9) is the output signal function of the sensor:
PDV β=f 3.7β(SS β)           (3.7) PDV β = f 3.7β (SS β ) (3.7)
F 3.8={f 3.7β|f 3.7β编号β的可变分量数据,1≤β≤n}            (3.8) F 3.8 = {f 3.7β | f 3.7β Variable component data of number β, 1≤β≤n} (3.8)
SS β=f 3.9β(S β)              (3.9) SS β = f 3.9β (S β ) (3.9)
其中:in:
f 3.7β为编号为β的所述可变分量的函数,F 3.8为所述可变分量的函数集合,f 3.9β是传感器函数,n为所述可变分量的函数的总数,n、β均属于自然数,且1≤β≤n。 f 3.7β is the function of the variable component numbered β, F 3.8 is the function set of the variable component, f 3.9β is the sensor function, n is the total number of functions of the variable component, n, β All belong to natural numbers, and 1≤β≤n.
PDV β为编号为β的所述可变分量,SS β为编号为β的所述传感器所输出的信号,S β为编号为β的所述传感器。 PDV β is the variable component numbered β, SS β is the signal output by the sensor numbered β, and S β is the sensor numbered β.
S3030步骤,按照公式(3.10)确定的所述固定分量和所述传感器或所述统计预测的输出信号之间的函数关系,监测所述固定分量,按照公式(3.11)建立所述固定分量的函数集合,公式(3.12)是所述传感器或所述统计预测的输出信号函数:Step S3030, monitor the fixed component according to the functional relationship between the fixed component determined by the formula (3.10) and the output signal of the sensor or the statistical prediction, and establish the function of the fixed component according to the formula (3.11). Set, formula (3.12) is the output signal function of the sensor or the statistical prediction:
PDF γ=f 3.10γ(SS γ)              (3.10) PDF γ = f 3.10 γ (SS γ ) (3.10)
F 3.11={f 3.10γ|f 3.10γ编号β的固定分量数据,0≤γ≤p}          (3.11) F 3.11 = {f 3.10γ | f 3.10γ Fixed component data of number β, 0≤γ≤p} (3.11)
SS γ=f 3.12γ(s γ)           (3.12) SS γ =f 3.12γ (s γ ) (3.12)
其中:in:
f 3.10γ为编号为γ的所述固定分量的函数,F 3.11为所述固定分量的函数集合,f 3.12γ是所述传感器或所述统计预测的输出信号函数,p为所述固定分量的函数的总数,p、γ均属于自然数,且0≤γ≤p,p=0为不包括固定分量。 f 3.10γ is the function of the fixed component numbered γ, F 3.11 is the function set of the fixed component, f 3.12γ is the output signal function of the sensor or the statistical prediction, p is the fixed component The total number of functions, p and γ are both natural numbers, and 0≤γ≤p, p=0 does not include fixed components.
PDF γ为编号为γ的所述固定分量,SS γ为编号为γ的所述传感器或所述统计预测所输出的信号,S γ为编号为γ的所述传感器或所述统计预测。 PDF γ is the fixed component numbered γ, SS γ is the signal output by the sensor numbered γ or the statistical prediction, S γ is the sensor numbered γ or the statistical prediction.
S3040步骤,按照公式(3.13)确定的所述扩展分量和所述传感器的输出信号之间的函数关系,监测所述扩展分量,按照公式(3.14)建立所述扩展分量的函数集合,公式(3.15)是所述传感器的输出信号函数:Step S3040, monitor the extended component according to the functional relationship between the extended component determined by the formula (3.13) and the output signal of the sensor, and establish a function set of the extended component according to the formula (3.14), the formula (3.15 ) is the output signal function of the sensor:
Figure PCTCN2021092129-appb-000005
Figure PCTCN2021092129-appb-000005
Figure PCTCN2021092129-appb-000006
Figure PCTCN2021092129-appb-000006
Figure PCTCN2021092129-appb-000007
Figure PCTCN2021092129-appb-000007
其中:in:
Figure PCTCN2021092129-appb-000008
为编号为
Figure PCTCN2021092129-appb-000009
的所述扩展分量的函数,F 3.14为所述扩展分量的函数集合,
Figure PCTCN2021092129-appb-000010
是所述传感器的输出信号函数,n为所述扩展分量的函数的总数,
Figure PCTCN2021092129-appb-000011
φ均属于自然数,
Figure PCTCN2021092129-appb-000012
φ=0为不包括扩展分量。
Figure PCTCN2021092129-appb-000008
is numbered as
Figure PCTCN2021092129-appb-000009
The function of the extended component, F 3.14 is the function set of the extended component,
Figure PCTCN2021092129-appb-000010
is the output signal function of the sensor, n is the total number of functions of the extended component,
Figure PCTCN2021092129-appb-000011
φ are all natural numbers,
Figure PCTCN2021092129-appb-000012
φ=0 means that the extension component is not included.
Figure PCTCN2021092129-appb-000013
为编号为
Figure PCTCN2021092129-appb-000014
的所述扩展分量,
Figure PCTCN2021092129-appb-000015
为编号为β的所述传感器所输出的信号,
Figure PCTCN2021092129-appb-000016
为编号为
Figure PCTCN2021092129-appb-000017
的所述传感器。
Figure PCTCN2021092129-appb-000013
is numbered as
Figure PCTCN2021092129-appb-000014
The extended component of ,
Figure PCTCN2021092129-appb-000015
for the signal output by the sensor numbered β,
Figure PCTCN2021092129-appb-000016
is numbered as
Figure PCTCN2021092129-appb-000017
of the sensor.
2.4:背景噪声2.4: Background noise
在前述技术方案的基础上,本发明包括但不限于背景噪声的处理步骤,具体可以采用如下列的或者多种局部改进的措施:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, the processing steps of background noise. Specifically, the following or various local improvement measures can be adopted:
S4010步骤,对于存在所述背景噪声的所述对象,按照以下步骤计算:Step S4010, for the object with the background noise, calculate according to the following steps:
按照公式(4.1)建立含背景噪声的所述监测函数,According to formula (4.1), the monitoring function with background noise is established,
按照公式(4.2)设定所述背景噪声为所述固定分量,According to formula (4.2), the background noise is set as the fixed component,
按照公式(4.3)建立含背景噪声的所述扩展分量函数,The extended component function with background noise is established according to formula (4.3),
按照公式(4.4)建立所述可变分量的传感器函数,The sensor function of the variable component is established according to equation (4.4),
设定公式(4.5)为所述背景噪声的函数,Setting formula (4.5) as a function of the background noise,
按照公式(4.6)计算所述监测值,Calculate the monitoring value according to formula (4.6),
MI=f 4.1(PDV,PDF,PDE,PDN)           (4.1) MI=f 4.1 (PDV, PDF, PDE, PDN) (4.1)
PDF=f 4.2(PDN)        (4.2) PDF=f 4.2 (PDN) (4.2)
PDE=f 4.3(SE,PDN)              (4.3) PDE = f 4.3 (SE, PDN) (4.3)
PDV=f 4.4(SV)             (4.4) PDV=f 4.4 (SV) (4.4)
PDN=f 4.5(t)          (4.5) PDN=f 4.5 (t) (4.5)
MI=f 4.6(SV,SE,t)             (4.6) MI = f 4.6 (SV, SE, t) (4.6)
其中,f 4.1为包含背景噪声的所述监测函数,f 4.2为以所述背景噪声为所述固定分量的函数,f 4.3为含背景噪声的所述扩展分量函数,f 4.4为所述可变分量的传感器函数,f 4.5为所述背景噪声的函数,f 4.6为所述监测值函数,PDN为背景噪声,SE为所述扩展分量的传感器输出信号,SV为所述可变分量的传感器输出信号,t为时间序列。 Wherein, f 4.1 is the monitoring function including background noise, f 4.2 is the function with the background noise as the fixed component, f 4.3 is the extended component function including background noise, and f 4.4 is the variable component sensor function, f 4.5 is the function of the background noise, f 4.6 is the monitoring value function, PDN is the background noise, SE is the sensor output signal of the extended component, SV is the sensor output of the variable component signal, t is the time series.
在本实施例中,对于激光拉曼分析仪的葡萄糖监测,选择背景噪声为CCD阵列的电背景噪声和体外葡萄糖监测的对象本身所特有的葡萄糖信号,包括表皮、皮下组织、组织间液等不属于国际卫生组织定义的静脉血管中的葡萄糖。对于背景噪声的监测,依据本发明,业内的中级技术人员,可以根据自己的理解来进行细化的组合,采用激光拉曼分析仪或其他监测设备组合监测。In this embodiment, for the glucose monitoring of the laser Raman analyzer, the background noise is selected as the electrical background noise of the CCD array and the glucose signal unique to the object of in vitro glucose monitoring, including epidermis, subcutaneous tissue, interstitial fluid, etc. Glucose in venous blood vessels as defined by the International Health Organization. For the monitoring of background noise, according to the present invention, the intermediate technicians in the industry can make a detailed combination according to their own understanding, and use a laser Raman analyzer or other monitoring equipment for combined monitoring.
S4020步骤,根据实际应用,在单一变量监测的情况下,在所述可变分量的传感器的量程满足应用的情况下,采用一个所述可变分量的传感器,在所述可变分量的传感器的量程不满足应用的情况下,采用多个所述可变分量的传感器以延展量程。Step S4020, according to the actual application, in the case of single-variable monitoring, and in the case that the range of the variable-component sensor satisfies the application, adopt one of the variable-component sensors, and in the case of the variable-component sensor In the case that the range does not satisfy the application, a plurality of the variable component sensors are used to extend the range.
对于血糖值的监测,另外一种优选方案是基于血糖值4.2为界,进行划分,例如大于4.2的设计一段监测,小于等于4.2的设计为另外一段监测。For blood glucose monitoring, another preferred solution is to divide the blood glucose value based on 4.2 as the boundary. For example, if the blood glucose value is greater than 4.2, one section of monitoring is designed, and if the blood glucose value is less than or equal to 4.2, another section of monitoring is designed.
S4030步骤,根据实际应用,在多变量监测的情况下,每个变量采用一个所述可变分量的传感器。In step S4030, according to the actual application, in the case of multi-variable monitoring, each variable adopts one sensor of the variable component.
在本实施例中,采用激光拉曼分析仪和红外光分析仪就是这样的设计方案。In this embodiment, the use of a laser Raman analyzer and an infrared light analyzer is such a design solution.
S4040步骤,根据实际应用,在所述可变分量的传感器的输出数据满足应用的情况下,不需要采用所述扩展分量的传感器,在所述可变分量的传感器的输出数据不能满足应用的情况下,采用一个以上所述扩展分量的传感器。Step S4040, according to the actual application, if the output data of the variable component sensor satisfies the application, it is not necessary to use the extended component sensor, and in the case that the output data of the variable component sensor cannot meet the application Next, use more than one sensor of the extended component described above.
2.5:对象算法2.5: Object Algorithms
在前述技术方案的基础上,本发明包括但不限于所述对象算法,具体可以采用如下列的或者多种局部改进的措施:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, the object algorithm. Specifically, the following or multiple local improvement measures can be adopted:
S5010步骤,采用标准的或者高一级测量精度测量准确度的监测设备,监测获取所述对象的监测值,以此作为所述约定真值,并记录监测的时刻,设定所述约定真值的误差为Δ,且Δ=0,设定所述允许误差为Δ eIn step S5010, standard or higher-level measurement accuracy monitoring equipment is used to monitor and obtain the monitoring value of the object as the agreed true value, record the monitoring time, and set the agreed true value The error is Δ, and Δ=0, and the allowable error is set as Δ e .
S5020步骤,设定初始参数集,采用所述当前的监测分量和包括扩展卡尔曼滤波器算法、蒙特卡洛粒子算法、现代贝叶斯算法在内的算法和所述初始参数集,计算所述对象修正值,再与根据所述S5010步骤计算所述约定真值,计算误差,如果所述误差落在所述允许误差之内,则赋值所述初始参数集为所述个性化参数集,如果所述误差大于所述允许误差,则修改所述初始参数集为所述个性化参数集,使得所述误差落在所述允许误差之内。Step S5020: Set an initial parameter set, and calculate the object correction value, and then calculate the agreed true value according to the step S5010, calculate the error, if the error falls within the allowable error, assign the initial parameter set to the personalized parameter set, if If the error is greater than the allowable error, the initial parameter set is modified to be the personalized parameter set, so that the error falls within the allowable error.
S5030步骤,采用经过所述个性化参数集,采用所述当前的监测分量和包括扩展卡尔曼滤波器算法、蒙特卡洛粒子算法、现代贝叶斯算法在内的算法和所述个性化参数集,计算所述对象修正值。Step S5030, using the personalized parameter set, using the current monitoring component and algorithms including extended Kalman filter algorithm, Monte Carlo particle algorithm, modern Bayesian algorithm, and the personalized parameter set , calculate the object correction value.
在本实施例中,采用T‐检验或Z‐检验分析误差,以剔除异常值。采用支持向量机SVM和卷积神经网络CNN算法,对于历史值进行分类。In this example, T-test or Z-test was used to analyze errors to remove outliers. The support vector machine SVM and the convolutional neural network CNN algorithm are used to classify the historical values.
S5040步骤,基于设定,采用所述历史的监测分量,依据设定的时间间隔,在所述时间间隔点执行所述S5020步骤,在所述时间间隔点之外,执行所述S5030步骤,建立与所述监测分量对应的个性化参数集和所述时间序列,记录到所述信息库,采用深度学习算法,计算所述信息库中的所述对象的所述监测分量、所述个性化参数集、所述时间序列,找出高概率的所述个性化参数集并标定对应的所述监测分量为优化点,所述高概率包括用户指定概率或概率大于30%的。Step S5040, based on the setting, using the historical monitoring component, according to the set time interval, execute the step S5020 at the time interval point, and execute the step S5030 outside the time interval point to establish The personalized parameter set and the time series corresponding to the monitoring components are recorded in the information database, and a deep learning algorithm is used to calculate the monitoring components and the personalized parameters of the objects in the information database set and the time series, find out the personalized parameter set with high probability and demarcate the corresponding monitoring component as the optimization point, and the high probability includes the probability specified by the user or the probability is greater than 30%.
S5050步骤,基于所述S5040步骤所获得的所述优化点的所述个性化参数集,采用包括支持向量机算法、卷积神经网络算法,计算所述对象修正值。In step S5050, based on the personalized parameter set of the optimization point obtained in the step S5040, the object correction value is calculated by adopting a support vector machine algorithm and a convolutional neural network algorithm.
在本实施例中,采用医用级的血糖、血脂的抽血化验测量设备获取个体的血糖和血脂的测量值和记录测量时刻,以此作为约定真值。同时,亦即在所述相同时段,采用待校准设备测量的血糖、血脂的数值和时间序列,计算纵向同步修正值,并计算和验证纵向同步修正值和约定真值之间的误差,如果误差大于允许误差,则修改参数集并迭代计算,直到误差小于允许误差。In this embodiment, a medical-grade blood glucose and blood lipid blood test measurement device is used to obtain the measured values of the individual's blood glucose and blood lipids and record the measurement time, which are used as the agreed true values. At the same time, that is, in the same period of time, the values and time series of blood glucose and blood lipid measured by the equipment to be calibrated are used to calculate the vertical synchronization correction value, and the error between the vertical synchronization correction value and the agreed true value is calculated and verified. If the error If it is greater than the allowable error, modify the parameter set and iteratively calculate until the error is less than the allowable error.
约定真值还可以采用对于其它个体的统计及人工智能算法等方法来获得,此时,无需采用高一级的医用设备测量获得。The agreed truth value can also be obtained by statistics of other individuals and artificial intelligence algorithms. At this time, it is not necessary to use higher-level medical equipment to measure and obtain.
在本实施例中,校准函数可以选用数学统计算法、支持向量机SVM和卷积神经网络CNN等算法,以误差小于允许误差作为目标,训练例如卷积核或相关参数,这些均归纳与个性化特征集。In this embodiment, the calibration function can select algorithms such as mathematical statistics algorithm, support vector machine SVM, convolutional neural network CNN, etc., with the error smaller than the allowable error as the goal, for example, the convolution kernel or related parameters are trained, which are all summarized and personalized feature set.
2.6:群体算法2.6: Swarm Algorithms
在前述技术方案的基础上,本发明包括但不限于所述群体算法,具体可以采用如下列的或者多种局部改进的措施:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, the group algorithm. Specifically, the following or multiple locally improved measures can be adopted:
S6010步骤,对所述群体中的全部所述对象,计算所述优化点和所述对象修正值,记录到所述信息库。Step S6010, for all the objects in the group, calculate the optimization point and the object correction value, and record them in the information database.
S6020步骤,依据所述信息库中的所述对象,针对所述优化点和所述对象修正值,建立一个以上的对象分类,并且标定所述对象的所述对象分类,所述对象分类的个数与所述对象的总数的比值大于用户指定数或者大于0.2,记录到所述信息库。Step S6020, according to the objects in the information database, for the optimization point and the object correction value, establish more than one object classification, and calibrate the object classification of the object, the individual classification of the object classification The ratio of the number to the total number of objects is greater than the number specified by the user or greater than 0.2, and is recorded in the information base.
S6030步骤,依据所述对象分类,对于所述优化点和所述对象修正值,依据误差最小原则,计算所述对象分类的个性化特征集,记录到所述信息库。Step S6030, according to the object classification, for the optimization point and the object correction value, according to the principle of minimum error, calculate the personalized feature set of the object classification, and record it in the information database.
S6040步骤,依据所述对象分类的个性化特征集,计算所述对象的所述群体修正值。Step S6040: Calculate the group correction value of the object according to the personalized feature set of the object classification.
S6050步骤,对于所述自身对象,计算标定所属于的所述对象分类,依据所述对象分类的个性化特征集,计算所述对象的所述对象修正值和所述群体修正值。Step S6050, for the self-object, calculate the object classification to which the calibration belongs, and calculate the object correction value and the group correction value of the object according to the personalized feature set of the object classification.
S6060步骤,依据所述对象分类的个性化特征集,对于新加入的所述对象,依据对所述对象的监测值的计算,确定其对象分类,直接采用该分类的所述个性化特征集中包括的所述约定真值,而无需执行监测所述约定真值的步骤。Step S6060, according to the personalized feature set of the object classification, for the newly added object, determine its object classification according to the calculation of the monitoring value of the object, and directly adopt the personalized feature set of the classification to include: said agreed truth value without performing the step of monitoring said agreed truth value.
所述个性化特征集包括所述对象的所述对象算法的参数、所述群体算法的参数、所述分类、所述约定真值。The personalized feature set includes the parameters of the object algorithm, the parameters of the population algorithm, the classification, and the agreed truth value of the object.
在本实施例中,采用群体之间算法可进一步提高校准的效率和减小误差,对于由于人体的生物多样性,例如不同的肤色、不同的年龄、不同的职业等情况,进行针对性地校准,以期获得更好的效果。In this embodiment, the use of the algorithm between groups can further improve the calibration efficiency and reduce the error. For the biological diversity of the human body, such as different skin colors, different ages, different occupations, etc., targeted calibration is performed. , in order to obtain better results.
进一步,建立群体分类模型,并建立分类的个性化特征集,对于新进入群体的个体,进行计算,以纳入分类,以该分类所对应的个性化特征集进行快速校准。Further, a group classification model is established, and a personalized feature set for classification is established. For individuals newly entering the group, calculation is performed to be included in the classification, and rapid calibration is performed with the personalized feature set corresponding to the classification.
2.7:差分对象算法2.7: Differential Object Algorithm
在前述技术方案的基础上,本发明包括但不限于包括差分对象算法,具体如下:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, a differential object algorithm, specifically as follows:
S7010步骤,计算所述对象在所述优化点的所述监测值与所述对象修正值的差值,记录到所述信息库。Step S7010: Calculate the difference between the monitoring value of the object at the optimization point and the correction value of the object, and record the difference in the information database.
S7020步骤,如果各个所述优化点的所述差值为常数差值,则对于后续时间序列的所述对象修正值,采用所述监测值减去所述常数差值,计算所述对象修正值。Step S7020, if the difference value of each of the optimization points is a constant difference value, for the object correction value of the subsequent time series, use the monitoring value to subtract the constant difference value to calculate the object correction value .
S7030步骤,如果各个所述优化点的所述差值为函数差值,则对于后续时间序列的所述对象修正值,采用所述监测值减去所述函数差值,计算所述对象修正值。Step S7030, if the difference value of each optimization point is a function difference value, then for the object correction value of the subsequent time series, subtract the function difference value from the monitoring value to calculate the object correction value .
S7040步骤,如果所述时间序列的所述优化点的所述差值为所述常数差值和所述函数差值的交替差值,采用所述监测值减去所述交替差值,计算所述对象修正值。Step S7040, if the difference value of the optimization point of the time series is an alternating difference value between the constant difference value and the function difference value, subtract the alternating difference value from the monitoring value to calculate the object correction value.
S7050步骤,对于拉曼光谱监测的方法,采用两次以上频率具有微小频偏的激发光扫描所述对象产生两个以上拉曼光谱,依据所述对象的拉曼散射特征位移,对两次以上扫描产生的所述拉曼散射光谱做差分卷积或线性回归计算,以消除由于荧光所带来的背景噪声干扰,所述微小频偏的激发光波长差距在0.2至100nm之间。In step S7050, for the Raman spectrum monitoring method, the object is scanned twice or more with excitation light with a slight frequency offset to generate two or more Raman spectra, and according to the Raman scattering characteristic shift of the object, the two or more The Raman scattering spectrum generated by scanning is calculated by differential convolution or linear regression to eliminate the interference of background noise caused by fluorescence, and the wavelength difference of the excitation light with the slight frequency offset is between 0.2 and 100 nm.
在本实施例中,对于激光拉曼光谱分析仪和红外光谱分析仪,均采用差分对象算法,以进一步对抗背景噪声的影响和提高监测精确度准确度。In this embodiment, for the laser Raman spectrum analyzer and the infrared spectrum analyzer, the differential object algorithm is used to further counteract the influence of background noise and improve the monitoring accuracy.
2.8:个性化特征集2.8: Personalization Feature Sets
在前述技术方案的基础上,本发明包括但不限于所述个性化特征集,具体可以采用如下列的或者多种局部改进的措施:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, the personalized feature set. Specifically, the following or various local improvement measures can be adopted:
S8010步骤,设定约束条件为所述对象的所述修正值误差小于所述允许误差,按照公式(8.1)建立所述个性化特征集,计算所述个性化特征集:Step S8010, set a constraint condition that the error of the corrected value of the object is less than the allowable error, establish the personalized feature set according to formula (8.1), and calculate the personalized feature set:
PF=f 8.1(MI,MIF,Δ≤Δ E)             (8.1) PF=f 8.1 (MI, MIF, Δ≤Δ E ) (8.1)
其中,f 8.1为个性化特征集函数,PF为所述个性化特征集,MI为所述监测值或监测值数据集合,MIF为所述对象修正值或对象修正值集合,Δ为误差,Δ E为允许误差。 Wherein, f 8.1 is the personalized feature set function, PF is the personalized feature set, MI is the monitoring value or the monitoring value data set, MIF is the object correction value or the object correction value set, Δ is the error, Δ E is the allowable error.
S8020步骤,分解所述个性化特征集:Step S8020, decompose the personalized feature set:
基于指定,将所述个性化特征集分解为一个以上个性化特征集类别,并且将所述个性 化特征集类别分解为包括一个以上个性化特征集类别分量。Based on the specification, the personalization feature set is decomposed into more than one personalized feature set category, and the personalized feature set category is decomposed into one or more personalized feature set category components.
所述个性化特征集与所述个性化特征集类别之间具有公式(8.2)所确定的函数关系:There is a functional relationship determined by formula (8.2) between the personalized feature set and the category of the personalized feature set:
PF=f 8.2(PFT)                (8.2) PF=f 8.2 (PFT) (8.2)
其中,f 8.2为所述个性化特征集的类别函数,PFT为所述个性化特征集类别,所述分解包括从便于计算角度的频域分解,还包括从连续时间角度的时域分解。 Wherein, f 8.2 is the category function of the personalized feature set, PFT is the category of the personalized feature set, and the decomposition includes frequency domain decomposition from the perspective of convenient calculation, and also includes time domain decomposition from the perspective of continuous time.
S8030步骤,监测所述个性化特征集类别的时域值:Step S8030, monitoring the time domain value of the personalized feature set category:
所述个性化特征集类别与所述连续时间序列之间具有公式(8.3)所确定的函数关系,按照公式(8.3)监测所述个性化特征集类别的时域值:There is a functional relationship between the personalized feature set category and the continuous time series determined by formula (8.3), and the time domain value of the personalized feature set category is monitored according to formula (8.3):
PFT=f 8.3(t)                (8.3) PFT=f 8.3 (t) (8.3)
其中,f 8.3为个性化特征集类别时域函数,t为所述连续时间序列。 Among them, f 8.3 is the personalized feature set category time domain function, and t is the continuous time series.
S8040步骤,监测所述个性化特征集类别的特定时刻值:Step S8040, monitor the specific moment value of the personalized feature set category:
所述个性化特征集类别的所述特定时刻值与所述特定时刻之间具有公式(8.4)所确定的函数关系,按照公式(8.4)监测所述个性化特征集类别的特定时刻值:There is a functional relationship between the specific moment value of the personalized feature set category and the specific moment, and the specific moment value of the personalized feature set category is monitored according to the formula (8.4):
PFT T=f 8.3(t,t=T)                  (8.4) PFT T = f 8.3 (t, t = T) (8.4)
其中,f 8.3为所述个性化特征集类别时域函数,T为所述特定时刻,PFT T为所述个性化特征集类别在所述特定时刻的特定时刻值。 Wherein, f 8.3 is the time domain function of the personalized feature set category, T is the specific moment, and PFT T is the specific moment value of the personalized feature set category at the specific moment.
S8050步骤,监测个性化特征集类别分量的时域值:Step S8050, monitor the time domain value of the category component of the personalized feature set:
按照公式(8.5)分解所述个性化特征集类别为一个以上所述个性化特征集类别分量,所述个性化特征集类别分量与所述连续时间序列之间具有公式(8.6)所确定的函数关系,按照公式(8.5)监测所述个性化特征集类别分量的时域值:The personalized feature set category is decomposed into more than one personalized feature set category component according to formula (8.5), and the personalized feature set category component and the continuous time series have the function determined by formula (8.6) relationship, monitor the time domain value of the category component of the personalized feature set according to formula (8.5):
PFT=f 8.5(PFT 1,PFT 2,…,PFT q)             (8.5) PFT=f 8.5 (PFT 1 , PFT 2 , . . . , PFT q ) (8.5)
PFT δ=f 8.6(t,1≤δ≤q)                  (8.6) PFT δ = f 8.6 (t, 1≤δ≤q) (8.6)
其中,f 8.5为个性化特征集类别分解函数,f 8.6为个性化特征集类别分量时域函数,PFT 1,PFT 2,…,PFT q为所述个性化特征集类别分量,q为所述个性化特征集类别分量的总数,δ为所述个性化特征集类别分量编号,q、δ均属自然数,且1≤δ≤q,PFT δ为编号为δ的所述个性化特征集类别分量在所述连续时间序列的时域值。 Wherein, f 8.5 is the category decomposition function of the personalized feature set, f 8.6 is the time domain function of the category component of the personalized feature set, PFT 1 , PFT 2 , ..., PFT q are the category components of the personalized feature set, and q is the The total number of category components of the personalized feature set, δ is the category component number of the personalized feature set, q and δ are both natural numbers, and 1≤δ≤q, PFT δ is the category component of the personalized feature set numbered δ The time domain value in the continuous time series.
S8060步骤,监测所述个性化特征集类别分量的特定时刻值:Step S8060, monitor the specific moment value of the category component of the personalized feature set:
所述个性化特征集类别分量在所述特定时刻的所述特定时刻值与所述连续时间序列具有公式(8.7)所确定的函数关系,按照公式(8.7)监测所述个性化特征集类别分量在特定时刻的所述特定时刻值:The specific time value of the category component of the personalized feature set at the specific time has a functional relationship determined by the formula (8.7) with the continuous time series, and the category component of the personalized feature set is monitored according to the formula (8.7). The specific moment value at a specific moment:
PFT δT=f 8.6(t,t=T,1≤δ≤q)                (8.7) PFT δT = f 8.6 (t, t=T, 1≤δ≤q) (8.7)
其中,PFT δT为在所述特定时刻所述个性化特征集类别分量的所述特定时刻值。 Wherein, PFT δT is the specific time value of the category component of the personalized feature set at the specific time.
在本实施例中,把全部算法公式中的参数和变量和采集的时间序列均作为个性化参数集的内容,采用标准化作业列入数据库,以便后续算法使用,尤其是深度学习算法。In this embodiment, the parameters and variables in all the algorithm formulas and the collected time series are taken as the content of the personalized parameter set, and are listed in the database using standardized work for subsequent algorithm use, especially the deep learning algorithm.
2.9:个性化特征集数学模型2.9: Personalized Feature Set Mathematical Model
在前述技术方案的基础上,本发明包括但不限于所述个性化特征集的数学模型,具体可以采用如下列的或者多种局部改进的措施:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, the mathematical model of the personalized feature set. Specifically, the following or various local improvement measures can be adopted:
S9010步骤,模糊优化法:Step S9010, fuzzy optimization method:
依据下列数学模型,包括模糊方程、模糊偏微分方程、集合方程,优化所述监测值和 所述监测分量,获取在优化的情况下的所述对象的最优值,具体包括:According to the following mathematical models, including fuzzy equations, fuzzy partial differential equations, and set equations, the monitoring value and the monitoring component are optimized to obtain the optimal value of the object under the optimized situation, specifically including:
S9011步骤,建立集合:Step S9011, create a set:
以所述监测值为元素建立监测值集合,记为MIset。A monitoring value set is established with the monitoring value elements, which is recorded as MIset.
以所述监测分量为元素建立监测分量集合,记为MI αset,α为所述监测分量的编号。 A monitoring component set is established with the monitoring components as elements, denoted as MI α set, where α is the number of the monitoring components.
以所述对象为元素建立对象集合,记为PDset;Create an object set with the object as an element, denoted as PDset;
分解监测值集合为可变值集合和固定值集合。The monitoring value set is decomposed into a variable value set and a fixed value set.
分解可变值集合为可变分量集合,记可变值集合为PDVset,记可变分量集合为PDV βset,β为所述可变分量的编号。 The variable value set is decomposed into a variable component set, the variable value set is denoted as PDVset, the variable component set is denoted as PDV β set, and β is the number of the variable component.
分解固定值集合为固定分量集合,记固定值集合为PDFset,记固定分量集合为PDF γset,γ为所述固定分量的编号。 The fixed value set is decomposed into a fixed component set, the fixed value set is referred to as PDFset, the fixed component set is referred to as PDF γ set, and γ is the number of the fixed component.
分解扩展值集合为扩展分量集合,记扩展值集合为PDEset,记扩展值分量集合为
Figure PCTCN2021092129-appb-000018
为所述扩展分量的编号。
Decompose the extended value set as the extended component set, denote the extended value set as PDEset, and denote the extended value component set as
Figure PCTCN2021092129-appb-000018
is the number of the extended component.
以所述个性化特征集类别为元素建立个性化特征集集合,分量个性化特征集集合为个性化特征集分量集合,记个性化特征集集合为PFTset,记个性化特征集分量集合为PFT δset,δ为所述个性化特征集分量的编号。 Taking the personalized feature set category as an element to establish a personalized feature set set, the component personalized feature set set is a personalized feature set component set, and the personalized feature set set is recorded as PFTset, and the personalized feature set component set is recorded as PFT δ set, δ is the number of the individualized feature set component.
所述集合包括模糊集合和非模糊集合。The sets include fuzzy sets and non-fuzzy sets.
在本实施例中,为了便于管理,所有集合均采用模糊集合。In this embodiment, for the convenience of management, all sets adopt fuzzy sets.
S9012步骤,建立截集:Step S9012, create a cut set:
依据所述数学模型,依次建立集合之间的映射关系,以所述监测值集合和所述监测分量集合为主键进行排序,成为有序集合,并以从大到小进行正排序后取前λ个元素作为有序头截集,以从小到大反排序后取前μ个元素作为有序尾截集,具体如下:According to the mathematical model, the mapping relationship between the sets is established in turn, and the monitoring value set and the monitoring component set are used for sorting as the primary key to become an ordered set, and the first λ is taken after positive sorting from large to small. The elements are used as the ordered head cut set, and the first μ elements are taken as the ordered tail cut set after reverse sorting from small to large, as follows:
MIset λ=(mi|mi监测值正排序号θ≤λ}           (9.1) MIset λ = (mi|mi monitoring value positive sequence number θ≤λ} (9.1)
MI αset λ={mi δ|mi α监测分量正排序号θ≤λ}           (9.2) MI α set λ = {mi δ |mi α monitoring component positive sequence number θ≤λ} (9.2)
PDset λ={pd|pd对象正排序号θ≤λ}        (9.3) PDset λ = {pd|pd object positive sorting number θ≤λ} (9.3)
PDVset λ={pdv|pdv可变值正排序号θ≤λ}        (9.4) PDVset λ = {pdv|pdv variable value positive sort number θ≤λ} (9.4)
PDV βset λ={pdv β|pdv β可变分量正排序号θ≤λ}        (9.5) PDV β set λ ={pdv β |pdv β variable component positive sorting number θ≤λ} (9.5)
PDFset λ={pdf|pdf固定值正排序号θ≤λ}       (9.6) PDFset λ = {pdf|pdf fixed value positive sort number θ≤λ} (9.6)
PDF γset λ={pdf γ|pdf γ固定分量正排序号θ≤λ}       (9.7) PDF γ set λ = {pdf γ |pdf γ fixed component positive sorting number θ≤λ} (9.7)
PDEset λ={pde|pde扩展值正排序号θ≤λ}          (9.8) PDEset λ = {pde|pde extension value positive sort number θ≤λ} (9.8)
PDE γset λ={pde γ|pde γ扩展分量正排序号θ≤λ}        (9.9) PDE γ set λ ={pde γ |pde γ extended component positive sorting number θ≤λ} (9.9)
PFTset λ={pft|pft个性化特征集正排序号θ≤λ}      (9.10) PFTset λ = {pft|pft personalized feature set positive sorting number θ≤λ} (9.10)
PFT δset λ={pft δ|pft δ个性化特征集分量正排序号θ≤λ}        (9.11) PFT δ set λ ={pft δ |pft δ Personalized feature set component positive sorting number θ≤λ} (9.11)
MIset μ={mi|mi监测值反排序号η≤μ}         (9.12) MIset μ = {mi|mi monitoring value inverse order number η≤μ} (9.12)
MI αset μ={mi δ|mi α监测分量反排序号η≤μ}         (9.13) MI α set μ = {mi δ |mi α monitoring component reverse order number η≤μ} (9.13)
PDset μ={pd|pd对象反排序号η≤μ}       (9.14) PDset μ = {pd|pd object inverse ordering number η≤μ} (9.14)
PDVset μ={pdv|pdv可变值反排序号η≤μ}         (9.15) PDVset μ = {pdv|pdv variable value reverse order number η≤μ} (9.15)
PDV βset μ={pdv β|pdv β可变分量反排序号η≤μ}         (9.16) PDV β set μ ={pdv β |pdv β variable component inverse order number η≤μ} (9.16)
PDFset μ={pdf|pdf固定值反排序号η≤μ}           (9.17) PDFset μ = {pdf|pdf fixed value inverse sort number η≤μ} (9.17)
PDF γset μ={pdf γ|pdf γ固定分量反排序号η≤μ}           (9.18) PDF γ set μ = {pdf γ |pdf γ fixed component inverse ordering number η≤μ} (9.18)
PDEset μ={pde|pde扩展值反排序号η≤μ}        (9.19) PDEset μ = {pde|pde extension value inverse sort number η≤μ} (9.19)
PDE γset μ={pde γ|pde γ扩展分量反排序号η≤μ}        (9.20) PDE γ set μ = {pde γ |pde γ extended component inverse ordering number η≤μ} (9.20)
PFTset μ={pft|pft个性化特征集反排序号η≤μ}         (9.21) PFTset μ = {pft|pft personalized feature set inverse order number η≤μ} (9.21)
PFT δset μ={pft δ|pft γ个性化特征集分量反排序号η≤μ}           (9.22) PFT δ set μ ={pft δ |pft γ personalized feature set component inverse order number η≤μ} (9.22)
其中,MIset λ、MI αset λ、PDset λ、PDVset λ、PDV βset λ、PDFset λ、PDF γset λ、PDEset λ、PDE γset λ、PFTset λ、PFT δset λ为所述有序头截集,MIset μ、MI αset μ、PDset μ、PDVset μ、PDV βset μ、PDFset μ、PDF γset μ、PDEset μ、PDE γset μ、PFTset μ、PFT δset μ为所述有序尾截集,λ、μ为小于各自集合元素个数,也就是所述截集位置,属于自然数,θ为正排序编号,η为反排序编号。 Wherein, MIset λ , MI α set λ , PDset λ , PDVset λ , PDV β set λ , PDFset λ , PDF γ set λ , PDEset λ , PDE γ set λ , PFTset λ , PFT δ set λ are the ordered heads Cut set, MIset μ , MI α set μ , PDset μ , PDVset μ , PDV β set μ , PDFset μ , PDF γ set μ , PDEset μ , PDE γ set μ , PFTset μ , PFT δ set μ are the ordering For the tail cut set, λ and μ are less than the number of elements in the respective sets, that is, the position of the cut set, which belongs to a natural number, θ is the positive sorting number, and η is the reverse sorting number.
S9013步骤,训练所述截集:Step S9013, train the cutout:
持续监测记录所述监测值和所述对象到所述信息库,依据所述信息库中的信息,采用循环和递归计算,以训练所述有序头截集和所述有序尾截集,记录结果到所述信息库。Continuously monitor and record the monitoring value and the object to the information base, and according to the information in the information base, adopt cyclic and recursive calculation to train the ordered head cut set and the ordered tail cut set, Record the results to the repository.
S9014步骤,寻优所述截集:Step S9014, search for optimization of the interception set:
依据所述数学模型,按照公式(9.1)至公式(9.22),取λ=1,计算获取监测值最优值和监测分量最优值,所对应的所述对象同时作为最优值。取μ=1,计算获取监测值最差值和监测分量最差值,所对应的所述对象同时作为最差值。According to the mathematical model, according to formula (9.1) to formula (9.22), take λ=1, calculate and obtain the optimal value of the monitoring value and the optimal value of the monitoring component, and the corresponding object is also used as the optimal value. Taking μ=1, the worst value of the monitoring value and the worst value of the monitoring component are obtained by calculation, and the corresponding object is simultaneously regarded as the worst value.
在本实施例中,除了上述数据采用截集运算,对于激光拉曼光谱的特征峰和红外光光谱,也采用截集运算,以便加强监测效果。In this embodiment, in addition to the above-mentioned data using the interception operation, the characteristic peaks of the laser Raman spectrum and the infrared light spectrum also adopt the interception operation, so as to enhance the monitoring effect.
S9020步骤,建立偏微分模型:Step S9020, establish a partial differential model:
采用偏微分方程原理,按照公式(9.23)和公式(9.24)建立所述监测值、所述监测分量和所述可变分量、所述固定分量、所述扩展分量之间的函数,计算所述监测值、所述监测分量:Using the principle of partial differential equations, according to formula (9.23) and formula (9.24), establish functions between the monitoring value, the monitoring component, the variable component, the fixed component, and the extended component, and calculate the Monitoring value, the monitoring component:
Figure PCTCN2021092129-appb-000019
Figure PCTCN2021092129-appb-000019
Figure PCTCN2021092129-appb-000020
Figure PCTCN2021092129-appb-000020
其中:in:
f 9.23、f 9.24均是偏微分方程,MI′ 1是编号为1的所述监测分量的1阶导数,
Figure PCTCN2021092129-appb-000021
是编号为1所述监测分量的ε阶导数,MI′ m是编号为m的所述监测分量的1阶导数,
Figure PCTCN2021092129-appb-000022
是编号为m的所述监测分量的ε阶导数。PDV′ α是第α种包括一个以上与所述MI α有关联的所述可变分量的1阶导数。
Figure PCTCN2021092129-appb-000023
是第α种包括一个以上与所述MI α有关联的所述可变分量的υ阶导数。PDF′ α是第α种包括零个以上与所述MI α有关联的所述固定分量的1阶导数。
Figure PCTCN2021092129-appb-000024
是第α种包括零个以上与所述MI α有关联的所述固定分量的υ阶导数。PDE′ α是第α种包括零个以上与所述MI α有关联的所述扩展分量的1阶导数。
Figure PCTCN2021092129-appb-000025
是第α种包括零个以上与所述MI α有关联的所述可变分量的ξ阶导数。PFT′ α是第α种包括零个以上与所述MI α有关联的所述扩展分量的1阶导数。
Figure PCTCN2021092129-appb-000026
是第α种包括零个以上与所述MI α有关联的所述个性化特征集类别分量的∈阶导数。
Both f 9.23 and f 9.24 are partial differential equations, MI′ 1 is the first derivative of the monitoring component numbered 1,
Figure PCTCN2021092129-appb-000021
is the ε order derivative of the monitoring component numbered 1, MI′ m is the first order derivative of the monitoring component numbered m,
Figure PCTCN2021092129-appb-000022
is the ε order derivative of the monitoring component numbered m. PDV'α is the αth 1st derivative of the variable component that includes more than one associated with the MIα .
Figure PCTCN2021092129-appb-000023
is the ν order derivative of the αth that includes more than one of the variable components associated with the MI α . PDF' α is the α-th 1st derivative of the fixed component that includes zero or more of the fixed components associated with the MI α .
Figure PCTCN2021092129-appb-000024
is the ν order derivative of the αth species including zero or more of the fixed components associated with the MI α . PDE'α is the αth 1st derivative of the extended component that includes zero or more associated with the MIα .
Figure PCTCN2021092129-appb-000025
is the ξ-th derivative of the variable component that includes zero or more of the variable components associated with the MI α . PFT' α is the α-th 1st derivative of the extended component that includes zero or more components associated with the MI α .
Figure PCTCN2021092129-appb-000026
is the α-th derivative of the ε order that includes zero or more of the category components of the personalized feature set associated with the MI α .
其中,根据需要,函数f 9.23中的所述监测分量还采用f 9.24中的MI α替代。 Wherein, as required, the monitoring component in function f 9.23 is also replaced by MI α in f 9.24 .
其中,ε是所述监测分量导数的最高阶,υ是所述可变分量导数的最高阶,ξ是所述扩展分量导数的最高阶,ε、ν、ξ、∈均是自然数。Wherein, ε is the highest order of the monitored component derivative, υ is the highest order of the variable component derivative, ξ is the highest order of the extended component derivative, and ε, ν, ξ, and ε are all natural numbers.
在本实施例中,除了上述数据采用偏微分方程运算,对于激光拉曼光谱的特征峰和红外光光谱,也采用截集运算,以便加强监测效果。In this embodiment, in addition to the partial differential equation operation for the above data, the intercept operation is also used for the characteristic peaks of the laser Raman spectrum and the infrared light spectrum, so as to enhance the monitoring effect.
S9030步骤,极值优化法:Step S9030, extreme value optimization method:
依据所述偏微分方程和所述模糊偏微分方程,采用对包括公式(9.23)、公式(9.24)的所述偏微分方程中的自变量、因变量取极值的方法,以及求取任意所述自变量、所述因变量为0的时候,计算所述监测值和所述监测分量的方法,获取所述监测值和所述监测分量的所述最优值和所述最差值,以此获取所述对象的最优值。According to the partial differential equation and the fuzzy partial differential equation, the method of taking extreme values of the independent variable and the dependent variable in the partial differential equation including formula (9.23) and formula (9.24), and obtaining any When the independent variable and the dependent variable are 0, the method of calculating the monitoring value and the monitoring component is obtained, and the optimal value and the worst value of the monitoring value and the monitoring component are obtained to obtain This gets the optimal value for the object.
在本实施例中,对于激光拉曼光谱的特征峰、红外光光谱和血糖监测的瞬时值,均根据其极值进行优化。In this embodiment, the characteristic peaks of the laser Raman spectrum, the infrared light spectrum, and the instantaneous value of blood glucose monitoring are all optimized according to their extreme values.
S9031步骤,依据所述信息库随着时间推移而不断地更新,在定时或不定时情况下,实现多次学习和训练,采用包括T检验和Z检验的方法选出所述监测值和所述监测分量的所述最优值和所述监测值和所述监测分量的所述最差值的异常值,消除所述异常值,以此获取所述对象的异常值。In step S9031, according to the information base being continuously updated over time, in timed or irregular conditions, multiple learning and training are implemented, and methods including T test and Z test are used to select the monitoring value and the said monitoring value. The optimal value of the component and the abnormal value of the monitoring value and the worst value of the monitoring component are monitored, and the abnormal value is eliminated, thereby obtaining the abnormal value of the object.
S9040步骤,概率优化法:Step S9040, probability optimization method:
在所述信息库中,选取不同时间段采集的所述对象监测值和所述对象扩展分量,计算所述监测值和所述监测分量,计算所述监测值和所述监测分量为最大值和最小值时对应的所述对象,采用包括贝叶斯算法在内的概率计算方法,统计所述监测值和所述监测分量为最大值和最小值时,所述对象中所述可调对象监测值和所述可调对象扩展分量出现相近值的概率,并对高概率验证做验证。In the information base, the object monitoring value and the object extension component collected in different time periods are selected, the monitoring value and the monitoring component are calculated, and the monitoring value and the monitoring component are calculated as the maximum value and the When the object corresponding to the minimum value, the probability calculation method including the Bayesian algorithm is used, and when the statistics of the monitoring value and the monitoring component are the maximum value and the minimum value, the adjustable object in the object is monitored. The probability that the value and the extension component of the adjustable object have similar values, and the high probability verification is verified.
标定在所述监测值和所述监测分量为最大值时的所述对象中所述可调对象监测值和所述可调对象扩展分量为优化可调对象监测值和优化可调对象扩展分量,标定在所述监测值和所述监测分量为最小值时的所述对象中所述可调对象监测值和所述可调对象扩展分量为劣化可调对象监测值和劣化可调对象扩展分量。Calibrating the adjustable object monitoring value and the adjustable object extension component in the object when the monitoring value and the monitoring component are maximum values are the optimized adjustable object monitoring value and the optimized adjustable object extension component, The adjustable object monitoring value and the adjustable object extension component in the object when the monitoring value and the monitoring component are minimum values are calibrated to be a degraded adjustable object monitoring value and a degraded adjustable object extension component.
在本实施例中,由于激光拉曼光谱仪的灵敏度非常高,受监测环境——例如外接光线、监测点的污染程度、监测个人的运动状态等——的影响,造成在连续的时间序列,监测到的激光拉曼光谱有一定的变化波动,因此采用概率优化的方法,消除干扰因素。In this embodiment, since the sensitivity of the laser Raman spectrometer is very high, it is affected by the monitoring environment (such as external light, the pollution level of the monitoring point, the movement state of the monitoring individual, etc.), resulting in continuous time series, monitoring The obtained laser Raman spectrum has certain fluctuations, so the method of probability optimization is adopted to eliminate the interference factors.
S9050步骤,神经网络优化法:Step S9050, neural network optimization method:
S9051步骤,依据包括所述数学模型,针对所述信息库中的关系型信息记录,以信息记录作为神经元,以包括所述数学模型的计算结果建立所述神经元之间的连接函数,构成一层以上的神经网络。Step S9051, according to including the mathematical model, for the relational information records in the information base, using the information records as neurons, and establishing a connection function between the neurons with the calculation results including the mathematical model, forming A neural network with more than one layer.
S9052步骤,依据所述连接函数中,所述优化可调对象监测值和优化可调对象扩展分量对于所述监测值和所述监测分量产生的效果,划分和建立兴奋型、抑制型、爆发型、平台期型的连接子函数,所述连接子函数包括常数型权重系数、函数型权重系数。Step S9052, according to the connection function, according to the effect of the optimized adjustable object monitoring value and the optimized adjustable object extended component on the monitored value and the monitored component, divide and establish an excitatory type, an inhibitory type, and an explosive type. , a platform-type linker function, the linker function includes a constant-type weight coefficient and a function-type weight coefficient.
S9053步骤,采用深度学习算法,包括监督学习、无监督学习、强化学习算法,优化所述连接子函数。Step S9053, using deep learning algorithms, including supervised learning, unsupervised learning, and reinforcement learning algorithms, to optimize the connection sub-function.
S9054步骤,采用支持向量机算法,分类筛选所述监测值和所述监测分量,并且筛选出所述优化可调对象监测值和优化可调对象扩展分量。In step S9054, a support vector machine algorithm is used to classify and screen the monitoring value and the monitoring component, and screen out the optimized adjustable object monitoring value and the optimized adjustable object extended component.
S9055步骤,采用卷积神经网络算法,对于所述对象之间忽略关联的条件下,实施卷积、激活、池化、全连接、训练所述连接子函数,以筛选出包括优化的所述监测值和所述 监测分量。Step S9055, using a convolutional neural network algorithm, for the condition of ignoring the association between the objects, implementing convolution, activation, pooling, full connection, and training the connection sub-function to filter out the monitoring including optimization. value and the monitored component.
S9056步骤,采用循环神经网络算法,对于所述对象之间需要关联的条件下,建立层内关联函数,训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量。In step S9056, a cyclic neural network algorithm is used to establish an intra-layer correlation function under the condition that the objects need to be correlated, and the linker function is trained to screen out the monitoring value and the monitoring component including the optimization.
S9057步骤,采用深度神经网络算法,对于各个所述神经网络的层之间的所述对象、所述监测值、所述监测分量需要建立关联的条件下,建立层间关联函数,训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量。In step S9057, a deep neural network algorithm is used to establish an inter-layer correlation function under the condition that the object, the monitoring value and the monitoring component between the layers of the neural network need to be correlated, and the connection is trained. sub-function to filter out the monitoring value and the monitoring component including optimization.
S9058步骤,采用前馈神经网络算法,对于所述每个神经元只与前一层的神经元相连的条件下,训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量。In step S9058, a feedforward neural network algorithm is used to train the connection sub-function under the condition that each neuron is only connected to the neurons of the previous layer, so as to filter out the monitoring value including the optimized monitoring value and the Monitor quantities.
S9059步骤,采用反馈神经网络算法,对于所述每个神经元只与后一层的神经元相连的条件下,训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量。In step S9059, a feedback neural network algorithm is used to train the connection sub-function under the condition that each neuron is only connected to the neuron of the next layer, so as to filter out the monitoring value including the optimized monitoring value and the monitoring value. weight.
在本实施例中,神经网络优化法主要应用在对象算法、群体算法和个性化特征集的计算中。其中,在对象算法中,可以用于历史数据对于当前数据的校准,在群体算法中,可以用于其它对象对于自身对象的校准,而在个性化特征集中,可以用于个性化特征集的优化。In this embodiment, the neural network optimization method is mainly applied in the calculation of the object algorithm, the group algorithm and the personalized feature set. Among them, in the object algorithm, it can be used for the calibration of the historical data to the current data, in the group algorithm, it can be used for the calibration of other objects to its own object, and in the personalized feature set, it can be used for the optimization of the personalized feature set .
S9060步骤,可逆寻优法:Step S9060, reversible optimization method:
采用所述模糊优化法、所述极值优化法、所述概率优化法、所述神经网络优化法之间的任意组合、这些方法之内的任意组合的方法,计算所述监测值和所述监测分量达到最优或者其区间内的指定值时,使得结果信息能够可逆复现所述监测值和所述监测分量达到最优或者其区间内的指定值,所述监测分量之间的可逆关系。The monitoring value and the When the monitoring component reaches the optimum or the specified value within its interval, the result information can reversibly reproduce the monitoring value and the monitoring component reaches the optimum or the specified value within its interval, and the reversible relationship between the monitoring components .
在本实施例中,对于卡尔曼滤波器的逆向优化中,采用可逆寻优法。In this embodiment, in the reverse optimization of the Kalman filter, the reversible optimization method is adopted.
S9070步骤,定时复现法:Step S9070, timing repetition method:
依据所述数学模型和所述可逆关系,计算从当前时刻开始,所述监测值、所述监测分量到达优化值或者指定值时的定时时间序列值,即从当前时刻开始,经过所述定时时间序列值的时间时,所述监测值、所述监测分量到达优化值或者指定值。According to the mathematical model and the reversible relationship, calculate the timing time series value when the monitoring value and the monitoring component reach the optimal value or the specified value starting from the current moment, that is, starting from the current moment, after the timing time When the time of the sequence value is reached, the monitoring value and the monitoring component reach the optimal value or the specified value.
S9080步骤,延时复现法:Step S9080, delay reproduction method:
依据所述数学模型和所述可逆关系,当所述定时时间序列值小于预定健康考核时域值的情况下,计算需要延时时间差值,将所述延时时间差值加入到所述数学模型,以确保在所述预定健康考核时间的时点,所述监测值、所述监测分量到达优化值或者指定值。According to the mathematical model and the reversible relationship, when the timing time series value is less than the predetermined health assessment time domain value, calculate the required delay time difference, and add the delay time difference to the mathematical model. The model is used to ensure that the monitoring value and the monitoring component reach the optimal value or the specified value at the time point of the predetermined health assessment time.
2.10:网络及大数据2.10: Network and Big Data
在前述技术方案的基础上,本发明包括但不限于网络处理步骤,具体可以采用如下列的或者多种局部改进的措施:On the basis of the foregoing technical solutions, the present invention includes, but is not limited to, network processing steps. Specifically, the following or multiple local improvement measures can be adopted:
SA100步骤,云大数据模式:SA100 steps, cloud big data model:
SA110步骤,建立基于互联网模式的云中心,将本发明所监测的包括全部所述群体、所述对象的全部信息、中间计算结果、所述信息库,以云终端形式通过广域网网络传输,全部存储到基于互联网的一个以上云服务器上,以此作为一个以上云中心,采用云计算模式管理、计算和支撑所述云终端。In step SA110, a cloud center based on the Internet model is established, and all information monitored by the present invention, including all the groups, all the information of the objects, the intermediate calculation results, and the information base, are transmitted through the wide area network network in the form of cloud terminals, and all stored One or more cloud servers based on the Internet are used as one or more cloud centers, and cloud computing mode is adopted to manage, calculate and support the cloud terminal.
SA120步骤,采用区块链模式建立一个以上云中心,以存储、管理和支撑所述信息库和前述的各个步骤,所述用户采用匿名记录,所述信息库中的信息采用带有时间戳的链式结构,用户访问所述信息库采用加解密通信,信息支持防篡改,支持防抵赖、多中心、无 中心模式。In step SA120, one or more cloud centers are established in the blockchain mode to store, manage and support the information base and the aforementioned steps. The users use anonymous records, and the information in the information base uses timestamped Chain structure, users access the information base through encryption and decryption communication, the information supports anti-tampering, and supports anti-repudiation, multi-center, and no-center modes.
SA130步骤,采用安全多方计算模式建立和管理和支撑一个以上机构,在所述机构之间,在不交换所述机构所属各自的所述云中心的所述信息库核心信息的前提下,依据各自所述机构的所述信息库内容进行约定的计算,所得的计算结果由参与的所述机构共享。所述机构包括一个以上所述云中心,管理一个以上所述对象。所述安全多方计算包括:公开密钥机制、混合电路、不经意传输、秘密共享、隐私保护集合交集协议、同态加密、零知识证明、无可信中心的方法,以增强信息的安全性和保护对象隐私。In step SA130, a secure multi-party computing model is used to establish, manage and support more than one organization. The content of the information base of the organization performs the agreed calculation, and the obtained calculation result is shared by the participating organizations. The organization includes one or more of the cloud centers and manages one or more of the objects. The secure multi-party computation includes: public key mechanisms, hybrid circuits, inadvertent transmission, secret sharing, privacy-preserving set intersection protocols, homomorphic encryption, zero-knowledge proofs, and methods without trusted centers to enhance information security and protection Object Privacy.
SA140步骤,采用集中学习模式建立和训练对于不强调对象隐私保护时的模型训练,所述信息库存储于一个云中心。In step SA140, the centralized learning mode is used to establish and train the model training when the object privacy protection is not emphasized, and the information database is stored in a cloud center.
S9150步骤,采用联邦学习模式建立和训练对于需要强调对象隐私保护时的模型训练,此时的所述模型训练在一个以上存储的云中心之间进行,各个所述云中心之间不交换各自的信息。In step S9150, the federated learning mode is used to establish and train the model training when the privacy protection of the object needs to be emphasized. At this time, the model training is performed between more than one stored cloud center, and the respective cloud centers do not exchange their respective cloud centers. information.
SA200步骤,局域网模式:SA200 steps, LAN mode:
建立基于局域网的服务器用于存储和管理支撑中心,将本发明所监测的包括全部群体、对象的全部信息、中间计算结果、所述信息库,以网络终端形式通过局域网网络传输,全部存储到基于局域网的服务器上,以此管理、计算和支撑。A local area network-based server is established to store and manage the support center, and all information including all groups and objects, intermediate calculation results, and the information base monitored by the present invention are transmitted through the local area network network in the form of network terminals, and all stored in the On the server of the local area network, in order to manage, calculate and support.
SA300步骤,单点模式:SA300 steps, single point mode:
所述单点为监测一个所述对象的监测、存储、管理、计算和支撑的步骤,将本发明所监测的对象的全部信息、中间计算结果、所述信息库,全部存储到所述单点的存储上,执行全部步骤。The single point is to monitor the steps of monitoring, storage, management, calculation and support of one of the objects, and all the information of the object monitored by the present invention, the intermediate calculation results, and the information base are all stored in the single point. storage, perform all steps.
在本实施例中,监测对象就是个人,采用支持无线移动的专用监测设备,该监测设备与个人的智能手机相连,再与公网的云服务器联网工作。为了加强个人隐私管理,为了采用区块链模式。在大数据的初期阶段,需要大量的带有不同时间段的采集到约定真值的个体的数据,以便在这个阶段之后,由深度学习来推理和分类,从而减少采集约定真值的动作,以减少实际成本支出和工作量。这里的函数拟合包括算术中值、算术均值、曲线中值、曲线均值、最小二乘法、高斯法、神经网络法等。In this embodiment, the monitoring object is an individual, and a dedicated monitoring device that supports wireless movement is used. The monitoring device is connected to the individual's smart phone, and then works with the cloud server of the public network. In order to strengthen personal privacy management, in order to adopt the blockchain model. In the initial stage of big data, a large amount of data of individuals with different time periods that have collected the agreed truth value is required, so that after this stage, deep learning can be used to reason and classify, so as to reduce the action of collecting the agreed truth value, and Reduce actual costs and workload. The function fitting here includes arithmetic median, arithmetic mean, curve median, curve mean, least squares method, Gaussian method, neural network method, etc.
实施例二、集装箱船货舱风机节能的监测方法Embodiment 2. Monitoring method for energy saving of fan in cargo hold of container ship
1、基础方案简介1. Introduction to the basic scheme
本实施例是作为本发明申请在工业领域中的应用举例。具体是在远洋集装箱船舶中,对于货舱大功率风机的节能控制,是一项多输入多输出的控制系统,其中输入量包括货舱中堆放的各个冷藏集装箱的周边环境温度、风速、箱内设定温度、货舱整体风场等,输出控制包括全部的货舱风机的变频调速、风道出风口风门、货舱进风口、货舱出风口、冷藏集装箱控制信号等,总体控制指标是在确保冷藏集装箱箱内货物保质、用户设定的箱内温度不变的情况下,尽可能减少货舱风机的能耗。据实际系统运行数据,采用本发明申请多模式监测的方法,可以实现风机控制更加合理平稳,节能效果高达58%。This embodiment is used as an example of the application of the present invention in the industrial field. Specifically, in ocean-going container ships, the energy-saving control of the high-power fan in the cargo hold is a multi-input and multi-output control system, in which the input includes the ambient temperature, wind speed, and in-box settings of each refrigerated container stacked in the cargo hold. The temperature, the overall wind field of the cargo hold, etc., the output control includes the frequency conversion speed regulation of all the cargo hold fans, the air duct air outlet damper, the cargo hold air inlet, the cargo hold air outlet, the refrigerated container control signal, etc. The overall control index is to ensure that the refrigerated container is in the box Under the condition that the quality of the goods and the temperature in the box set by the user remain unchanged, the energy consumption of the fan in the cargo compartment is reduced as much as possible. According to the actual system operation data, using the multi-mode monitoring method of the present invention, the fan control can be more reasonable and stable, and the energy saving effect is as high as 58%.
2、图示说明2. Illustration description
图6:其中如编号6010所示是货舱,货舱中堆放着冷藏集装箱(冷藏箱),在冷藏集装箱中,制冷机有一个闭环的温度控制系统,例如采用的是PID调节器的控制温度系统。在这个温度控制系统中,或者通过外置通信设备从冷藏集装箱的对外接口获取冷藏集装箱的包括内部设定温度、送风温度、回风温度、外部环境温度等信号,或者通过内置通信电路获取这些信号,这些信号通过如编号6036所示输出,作为负反馈信号如编号6032所示输入到系统的输入,与如编号6031所示的系统给定信号和如编号6033所示的AI给定信号一起,形成完整的如编号6043所示反馈信号,驱动如编号6020所示的风机控制子系统控制风机,最终形成如编号5035所示的控制理论上的闭环控制的方法。也就是说,依据采集的数据,作为闭环的负反馈数据去生成控制函数,直接去控制风机或者风机和闸门。但是需要注意的是,这里所提出的的闭环,是针对从采集到控制的过程时间而言,这个时间差比较短,例如小于20分钟。需要注意的是,这里的20分钟只是一个举例,根据不同大小的舱室,这个数字可以更长或者更短。Figure 6: As shown in the number 6010 is the cargo hold, in which are stacked refrigerated containers (refrigerated containers), and in the refrigerated containers, the refrigerator has a closed-loop temperature control system, such as a PID regulator control temperature system. In this temperature control system, signals including internal set temperature, supply air temperature, return air temperature, and external ambient temperature of the refrigerated container are obtained from the external interface of the refrigerated container through an external communication device, or these signals are obtained through a built-in communication circuit. Signals, which are output as indicated by number 6036 and input to the input of the system as negative feedback signals as indicated by number 6032, together with the system given signal as indicated by number 6031 and the AI given signal as indicated by number 6033 , form a complete feedback signal as shown in No. 6043, drive the fan control subsystem shown in No. 6020 to control the fan, and finally form a closed-loop control method in control theory as shown in No. 5035. That is to say, according to the collected data, the control function is generated as the closed-loop negative feedback data, and the fan or the fan and the gate are directly controlled. However, it should be noted that the closed loop proposed here is for the process time from acquisition to control, and this time difference is relatively short, for example, less than 20 minutes. It should be noted that the 20 minutes here is just an example, this number can be longer or shorter depending on the size of the cabin.
图3:与图6关联的控制方法,采如用图3的多输入多输出的状态空间控制方法。FIG. 3 : The control method associated with FIG. 6 , using the state-space control method with multiple inputs and multiple outputs as shown in FIG. 3 .
图7:其中编号7010和编号7020分别是船舶上一个货舱中堆放的冷藏集装箱的箱头所在的垂直平面,所述冷藏集装箱的箱头,是指冷藏集装箱在制冷机操作面板所在的一头。在船舶中,集装箱的堆放都有一个三维的坐标编号,即行号Bay、列号Row、层号Tier,简称BRT坐标。图7中,如编号7012、7022所示的白色方格是船底压载水舱的位置,如编号7011、7021所示的灰色方格是冷藏集装箱堆放的箱头,其中,箱头处的空气温度随着冷藏集装箱的工作而变化。为了便于描述,本发明专利申请用C1~C9示意该冷藏集装箱所在的位置点BRT坐标处的空气温度或者散热风扇的排风量、排风速度等数据,需要注意的是,该数据是连续量,图5中用C1~C9示意该连续量从小到大的不同,但这里并不意味着该连续量只分为C1~C9这9个等级。所述一个帧画面的数据,就是指对于一个货舱内的集装箱做一次采集,按照BRT坐标存放到环境数据的数据库。对于其它有源集装箱、无源集装箱或者非集装箱货物,以此类推。Figure 7: The numbers 7010 and 7020 are the vertical planes where the headers of the refrigerated containers stacked in a cargo hold on the ship are located respectively. The headers of the refrigerated containers refer to the end of the refrigerated containers where the operation panel of the refrigerator is located. In ships, the stacking of containers has a three-dimensional coordinate number, namely row number Bay, column number Row, layer number Tier, referred to as BRT coordinates. In Figure 7, the white squares indicated by numbers 7012 and 7022 are the positions of the bottom ballast tanks, and the gray squares indicated by numbers 7011 and 7021 are the headers of the refrigerated containers, where the air at the headers The temperature changes as the reefer container works. For the convenience of description, the patent application of the present invention uses C1 to C9 to indicate the data of the air temperature at the BRT coordinates of the location point of the reefer container or the exhaust air volume and exhaust speed of the cooling fan. It should be noted that this data is a continuous amount , C1 to C9 are used in FIG. 5 to indicate that the continuous quantities vary from small to large, but this does not mean that the continuous quantities are only divided into 9 levels of C1 to C9. The data of one frame picture refers to collecting once for a container in a cargo hold and storing it in the database of environmental data according to the BRT coordinates. And so on for other active containers, passive containers, or non-contained cargo.
3、差异化说明3. Differentiation description
与实施例一相同之处这里不再复述,不同之处有以下几点:The same points with the first embodiment will not be repeated here, and the differences are as follows:
3.1、3.1,
设定监测值为至少包括货舱内冷藏集装箱的位置坐标、环境温度、风速、箱内设定温度、出风口温度、送风口温度、货舱风机运行状态、货舱总体能耗。The set monitoring value includes at least the position coordinates of the refrigerated container in the cargo hold, the ambient temperature, the wind speed, the set temperature in the container, the temperature of the air outlet, the temperature of the air supply outlet, the operating status of the fan in the cargo hold, and the overall energy consumption of the cargo hold.
选用约定真值为历史记录值,设定监测因素值为货舱风机控制控制函数、货舱总体能耗函数。设定关联函数为冷藏集装箱控制函数、货舱风机控制函数、货舱温度控制函数、货舱能耗函数。The agreed truth value is selected as the historical record value, and the monitoring factor value is set as the control function of the fan in the cargo compartment and the overall energy consumption function of the cargo compartment. The correlation functions are set as refrigerated container control function, cargo hold fan control function, cargo hold temperature control function, and cargo hold energy consumption function.
设定对象为冷藏集装箱品牌型号,设定做种群体,其中每个货舱作为一个群体、每条船舶祖宗伟一个群体、每条航线作为一个群体。The set object is the brand and model of the reefer container, and the seed group is set, in which each cargo hold is a group, each ship is a group, and each route is a group.
3.2、3.2,
选定每个风机的控制或每个风机上的风门的控制作为纵向修正值,采用如图2所示的空间状态方程组作为关联函数、控制函数。对于每条船舶,采用各个货舱作为群体,进行 群体算法。The control of each fan or the control of the damper on each fan is selected as the longitudinal correction value, and the space state equation group shown in Figure 2 is used as the correlation function and the control function. For each ship, use each cargo hold as a group to perform a group algorithm.
3.3、3.3,
采用人工智能算法进行深度学习和标记,采用例如卷积神经网络CNN算法、贝叶斯Bayes算法、对抗神经网络GAN算法、萤火虫算法、蚁群算法等进行训练。优化的指标包括风机的能耗最小、设备动作最少(例如启停次数最少、启停风机个数最少)、对于内部温场扰动最少、对于出风数据扰动最少等策略,并且把实际的控制室结果按照时间存储到数据库,同时把能够获得的船舶航线数据、天气数据、集装箱的装卸数据以及停靠的码头数据等相关数据,全部输入到数据库。将这些都作为人工智能算法的深度学习的类容和经验内容,以便随着系统的运行,人工智能算法的结果变得越来越“聪明”,同时由于设备动作减少,同时也延长了设备的使用寿命。Artificial intelligence algorithms are used for deep learning and labeling, and training is performed using, for example, convolutional neural network CNN algorithm, Bayesian Bayes algorithm, adversarial neural network GAN algorithm, firefly algorithm, and ant colony algorithm. The optimized indicators include the minimum energy consumption of the fan, the least equipment action (for example, the minimum number of start and stop times, the minimum number of start and stop fans), the least disturbance to the internal temperature field, and the least disturbance to the air output data, and the actual control room. The results are stored in the database according to time, and all relevant data such as ship route data, weather data, container loading and unloading data, and docked terminal data that can be obtained are input into the database. These are used as the content and experience content of deep learning of artificial intelligence algorithms, so that as the system runs, the results of artificial intelligence algorithms become more and more "smarter", and at the same time, due to the reduction of equipment movements, it also prolongs the life of the equipment. service life.
3.4、3.4,
每条船舶采用数据通信卫星实时与云大数据中心联网,采用区块链和安全多方计算保护各个船舶、各个货主的信息。Each ship uses data communication satellites to connect to the cloud big data center in real time, and uses blockchain and secure multi-party computing to protect the information of each ship and each cargo owner.

Claims (10)

  1. 多模个性化监测的方法,其特征在于包括:The method for multimodal personalized monitoring is characterized by comprising:
    分解对象的监测值为一个以上监测分量,监测所述监测分量,分解所述监测分量包括一个以上可变分量和零个以上固定分量和与所述监测值存在监测函数的零个以上扩展分量;The monitoring value of the decomposition object is more than one monitoring component, the monitoring component is monitored, and the monitoring component is decomposed to include more than one variable component, more than zero fixed components, and more than zero extended components that have a monitoring function with the monitoring value;
    依据针对所述对象的历史的和当前的所述监测分量执行对象算法,得到与所述对象的约定真值误差小于允许误差的对象修正值;和/或,Execute an object algorithm according to the historical and current monitoring components for the object, and obtain an object correction value whose agreed true value error with the object is less than the allowable error; and/or,
    建立由一个以上具有相同监测值的所述对象构成的群体,采用大数据训练包括所述对象算法参数、群体算法参数、所述约定真值的个性化特征集,依据所述个性化特征集和其它对象修正自身对象的所述群体算法,得到群体修正值。Establish a group consisting of more than one object with the same monitoring value, and use big data to train a personalized feature set including the object algorithm parameters, group algorithm parameters, and the agreed truth value, according to the personalized feature set and Other objects modify the group algorithm of their own objects to obtain a group correction value.
  2. 根据权利要求1所述的方法,其特征在于,包括以下分解监测值的步骤:method according to claim 1, is characterized in that, comprises the step of following decomposition monitoring value:
    S2010步骤,所述可变分量为所述监测值中随着环境变化而变化的监测分量或用户指定的监测分量,所述可变分量采用传感器监测获得;Step S2010, the variable component is a monitoring component in the monitoring value that changes with environmental changes or a monitoring component specified by a user, and the variable component is obtained by sensor monitoring;
    S2020步骤,所述固定分量是一类在所述监测值中能够分离的所述监测分量,并且在同等于所述可变分量的采样周期内,所述固定分量的变化率与所述可变分量的变化率比值较小,对于生物健康类的优化选择,所述变化率比值小于0.20,对于工业类的优化选择,所述变化率比值小于0.10,并且,在此条件下,所述固定分量依据所述用户选择,采用传感器或统计预测来监测;In step S2020, the fixed component is a type of the monitoring component that can be separated in the monitoring value, and within a sampling period equal to the variable component, the rate of change of the fixed component is the same as that of the variable component. The ratio of the rate of change of the components is small, for the optimal selection of the biological health category, the ratio of the rate of change is less than 0.20, and for the optimal selection of the industrial category, the ratio of the rate of change is less than 0.10, and, under this condition, the fixed component monitoring using sensors or statistical predictions according to said user selection;
    S2030步骤,所述扩展分量采用传感器监测获得,所述扩展分量与所述监测值存在监测函数的所述监测函数包括:In step S2030, the extended component is obtained by using sensor monitoring, and the monitoring function of the extended component and the monitoring value exists in a monitoring function including:
    所述监测值的变化单方向影响所述扩展分量,即所述扩展分量是所述监测值的函数自变量,此时采用所述扩展分量作为所述监测值的辅助监测;The change of the monitoring value affects the extended component in one direction, that is, the extended component is a function argument of the monitoring value, and at this time, the extended component is used as the auxiliary monitoring of the monitoring value;
    所述监测值的变化双方向影响所述扩展分量,即所述扩展分量与所述监测值是互为函数自变量,此时采用所述扩展分量作为所述监测值的辅助监测和调节;The change of the monitoring value affects the extended component in both directions, that is, the extended component and the monitoring value are mutually independent variables, and at this time, the extended component is used as the auxiliary monitoring and adjustment of the monitoring value;
    所述扩展分量的变化单方向影响所述监测值,即所述监测值是所述扩展分量的函数自变量,此时采用所述扩展分量作为所述监测值的辅助调节;The change of the extended component affects the monitoring value in one direction, that is, the monitoring value is a function argument of the extended component, and at this time, the extended component is used as an auxiliary adjustment of the monitoring value;
    S2040步骤,依据不同的连续时间序列和特定时刻,持续监测所述监测值和所述监测分量,将中间数据和结果数据存储到信息库。In step S2040, the monitoring value and the monitoring component are continuously monitored according to different continuous time series and specific moments, and the intermediate data and result data are stored in the information base.
  3. 根据权利要求2所述的方法,其特征在于,所述监测函数还包括:The method of claim 2, wherein the monitoring function further comprises:
    S3010步骤,按照公式(3.1)建立所述监测值与所述对象的监测函数,按照公式(3.2)分解所述监测值为监测分量,包括所述可变分量、所述固定分量和所述扩展分量,按照公式(3.3)建立所述监测值与分量的监测函数,按照公式(3.4)建立可变分量集合,按照公式(3.5)建立固定分量集合,按照公式(3.6)建立扩展分量集合;In step S3010, a monitoring function between the monitoring value and the object is established according to formula (3.1), and the monitoring value is decomposed according to formula (3.2) to monitor components, including the variable component, the fixed component and the extended component component, according to formula (3.3) to establish the monitoring function of the monitoring value and the component, according to formula (3.4) to establish a variable component set, according to formula (3.5) to establish a fixed component set, according to formula (3.6) to establish an extended component set;
    MI=f 3.1(PD)                                    (3.1) MI = f 3.1 (PD) (3.1)
    PD=PDV∪PDF∪PDE                               (3.2)PD=PDV∪PDF∪PDE (3.2)
    MI=f 3.3(PDV,PDF,PDE)                          (3.3) MI=f 3.3 (PDV, PDF, PDE) (3.3)
    PDV={PDV β|PDV β编号β的可变分量数据,1≤β≤n}  (3.4) PDV={PDV β | PDV β number β variable component data, 1≤β≤n} (3.4)
    PDF={PDF γ|PDF γ编号γ的固定分量数据,0≤γ≤p}  (3.5) PDF = {PDF γ | PDF γ fixed component data of number γ, 0≤γ≤p} (3.5)
    Figure PCTCN2021092129-appb-100001
    Figure PCTCN2021092129-appb-100001
    其中,f 3.1为所述监测值与所述对象的所述监测函数,f 3.3为所述监测值与分量的所述监测函数,MI为所述监测值或监测值数据集合,PD为对象或对象数据集合,PDV为所述可变分量或可变数分量集合,PDF为所述固定分量或固定分量集合,PDE为所述扩展分量或所述扩展分量的集合,PDV β为编号为β的所述可变分量数据或所述可变分量数据集合的元素,n为所述可变分量的总数,PDF γ为编号为γ的固定分量数据或所述固定分量数据集合的元素,其中γ=0表示PDF为空集,指不包含所述固定分量,p为所述固定分量的总数,
    Figure PCTCN2021092129-appb-100002
    为编号为
    Figure PCTCN2021092129-appb-100003
    的扩展分量数据或所述扩展分量数据集合的元素,其中
    Figure PCTCN2021092129-appb-100004
    表示PDE为空集,指不包含所述固定分量,φ为所述扩展分量的总数,所述分解包括从便于监测角度的频域分解,还包括从连续时间角度的时域分解;和/或,
    Wherein, f 3.1 is the monitoring function of the monitoring value and the object, f 3.3 is the monitoring function of the monitoring value and the component, MI is the monitoring value or monitoring value data set, PD is the object or Object data set, PDV is the variable component or variable number component set, PDF is the fixed component or fixed component set, PDE is the extended component or the set of extended components, PDV β is the set of all the components numbered β. the variable component data or an element of the variable component data set, n is the total number of the variable components, PDF γ is the fixed component data numbered γ or an element of the fixed component data set, where γ=0 Indicates that the PDF is an empty set, which does not contain the fixed components, p is the total number of the fixed components,
    Figure PCTCN2021092129-appb-100002
    is numbered as
    Figure PCTCN2021092129-appb-100003
    The extended component data of or an element of the extended component data set, where
    Figure PCTCN2021092129-appb-100004
    Indicates that the PDE is an empty set, which means that the fixed component is not included, φ is the total number of the extended components, and the decomposition includes frequency domain decomposition from the perspective of monitoring convenience, and also includes time domain decomposition from the perspective of continuous time; and/or ,
    S3020步骤,按照公式(3.7)确定的所述可变分量和所述传感器的输出信号之间的函数关系,监测所述可变分量,按照公式(3.8)建立所述可变分量的函数集合,公式(3.9)是所述传感器的输出信号函数:Step S3020, monitor the variable component according to the functional relationship between the variable component determined by the formula (3.7) and the output signal of the sensor, and establish a function set of the variable component according to the formula (3.8), Equation (3.9) is the output signal function of the sensor:
    PDV β=f 3.7β(SS β)                               (3.7) PDV β = f 3.7β (SS β ) (3.7)
    F 3.8={f 3.7β|f 3.7β编号β的可变分量数据,1≤β≤n}  (3.8) F 3.8 = {f 3.7β | f 3.7β Variable component data of number β, 1≤β≤n} (3.8)
    SS β=f 3.9β(S β)                                  (3.9) SS β = f 3.9β (S β ) (3.9)
    其中:in:
    f 3.7β为编号为β的所述可变分量的函数,F 3.8为所述可变分量的函数集合,f 3.9β是传感器函数,n为所述可变分量的函数的总数,n、β均属于自然数,且1≤β≤n; f 3.7β is the function of the variable component numbered β, F 3.8 is the function set of the variable component, f 3.9β is the sensor function, n is the total number of functions of the variable component, n, β All belong to natural numbers, and 1≤β≤n;
    PDV β为编号为β的所述可变分量,SS β为编号为β的所述传感器所输出的信号,S β为编号为β的所述传感器; PDV β is the variable component numbered β, SS β is the signal output by the sensor numbered β, S β is the sensor numbered β;
    S3030步骤,按照公式(3.10)确定的所述固定分量和所述传感器或所述统计预测的输出信号之间的函数关系,监测所述固定分量,按照公式(3.11)建立所述固定分量的函数集合,公式(3.12)是所述传感器或所述统计预测的输出信号函数:Step S3030, monitor the fixed component according to the functional relationship between the fixed component determined by the formula (3.10) and the output signal of the sensor or the statistical prediction, and establish the function of the fixed component according to the formula (3.11). Set, formula (3.12) is the output signal function of the sensor or the statistical prediction:
    PDF γ=f 3.10γ(SS γ)                                 (3.10) PDF γ = f 3.10 γ (SS γ ) (3.10)
    F 3.11={f 3.10γ|f 3.10γ编号β的固定分量数据,0≤γ≤p}  (3.11) F 3.11 = {f 3.10γ | f 3.10γ Fixed component data of number β, 0≤γ≤p} (3.11)
    SS γ=f 3.12γ(S γ)                                   (3.12) SS γ =f 3.12γ (S γ ) (3.12)
    其中:in:
    f 3.10γ为编号为γ的所述固定分量的函数,F 3.11为所述固定分量的函数集合,f 3.12γ是所述传感器或所述统计预测的输出信号函数,p为所述固定分量的函数的总数,p、γ均属于自然数,且0≤γ≤p,p=0为不包括固定分量; f 3.10γ is the function of the fixed component numbered γ, F 3.11 is the function set of the fixed component, f 3.12γ is the output signal function of the sensor or the statistical prediction, p is the fixed component The total number of functions, p and γ are both natural numbers, and 0≤γ≤p, p=0 does not include fixed components;
    PDF γ为编号为γ的所述固定分量,SS γ为编号为γ的所述传感器或所述统计预测所输出的信号,S γ为编号为γ的所述传感器或所述统计预测; PDF γ is the fixed component numbered γ, SS γ is the signal output by the sensor numbered γ or the statistical prediction, S γ is the sensor numbered γ or the statistical prediction;
    S3040步骤,按照公式(3.13)确定的所述扩展分量和所述传感器的输出信号之间的函数关系,监测所述扩展分量,按照公式(3.14)建立所述扩展分量的函数集合,公式(3.15)是所述传感器的输出信号函数:Step S3040, monitor the extended component according to the functional relationship between the extended component determined by the formula (3.13) and the output signal of the sensor, and establish a function set of the extended component according to the formula (3.14), the formula (3.15 ) is the output signal function of the sensor:
    Figure PCTCN2021092129-appb-100005
    Figure PCTCN2021092129-appb-100005
    Figure PCTCN2021092129-appb-100006
    Figure PCTCN2021092129-appb-100006
    Figure PCTCN2021092129-appb-100007
    Figure PCTCN2021092129-appb-100007
    其中:in:
    Figure PCTCN2021092129-appb-100008
    为编号为
    Figure PCTCN2021092129-appb-100009
    的所述扩展分量的函数,F 3.14为所述扩展分量的函数集合,
    Figure PCTCN2021092129-appb-100010
    是所述传感器的输出信号函数,n为所述扩展分量的函数的总数,
    Figure PCTCN2021092129-appb-100011
    φ均属于自然数,
    Figure PCTCN2021092129-appb-100012
    φ=0为不包括扩展分量;
    Figure PCTCN2021092129-appb-100008
    is numbered as
    Figure PCTCN2021092129-appb-100009
    The function of the extended component, F 3.14 is the function set of the extended component,
    Figure PCTCN2021092129-appb-100010
    is the output signal function of the sensor, n is the total number of functions of the extended component,
    Figure PCTCN2021092129-appb-100011
    φ are all natural numbers,
    Figure PCTCN2021092129-appb-100012
    φ=0 means not including extended components;
    Figure PCTCN2021092129-appb-100013
    为编号为
    Figure PCTCN2021092129-appb-100014
    的所述扩展分量,
    Figure PCTCN2021092129-appb-100015
    为编号为β的所述传感器所输出的信号,
    Figure PCTCN2021092129-appb-100016
    为编号为
    Figure PCTCN2021092129-appb-100017
    的所述传感器。
    Figure PCTCN2021092129-appb-100013
    is numbered as
    Figure PCTCN2021092129-appb-100014
    The extended component of ,
    Figure PCTCN2021092129-appb-100015
    for the signal output by the sensor numbered β,
    Figure PCTCN2021092129-appb-100016
    is numbered as
    Figure PCTCN2021092129-appb-100017
    of the sensor.
  4. 根据权利要求2或3所述的方法,其特征在于,包括背景噪声的处理步骤:The method according to claim 2 or 3, characterized in that, comprising the processing step of background noise:
    S4010步骤,对于存在所述背景噪声的所述对象,按照以下步骤计算:Step S4010, for the object with the background noise, calculate according to the following steps:
    按照公式(4.1)建立含背景噪声的所述监测函数,According to formula (4.1), the monitoring function with background noise is established,
    按照公式(4.2)设定所述背景噪声为所述固定分量,According to formula (4.2), the background noise is set as the fixed component,
    按照公式(4.3)建立含背景噪声的所述扩展分量函数,The extended component function with background noise is established according to formula (4.3),
    按照公式(4.4)建立所述可变分量的传感器函数,The sensor function of the variable component is established according to equation (4.4),
    设定公式(4.5)为所述背景噪声的函数,Setting formula (4.5) as a function of the background noise,
    按照公式(4.6)计算所述监测值,Calculate the monitoring value according to formula (4.6),
    MI=f 4.1(PDV,PDF,PDE,PDN)                          (4.1) MI=f 4.1 (PDV, PDF, PDE, PDN) (4.1)
    PDF=f 4.2(PDN)                                        (4.2) PDF=f 4.2 (PDN) (4.2)
    PDE=f 4.3(SE,PDN)                                    (4.3) PDE = f 4.3 (SE, PDN) (4.3)
    PDV=f 4.4(SV)                                         (4.4) PDV=f 4.4 (SV) (4.4)
    PDN=f 4.5(t)                                          (4.5) PDN=f 4.5 (t) (4.5)
    MI=f 4.6(SV,SE,t)                                   (4.6) MI = f 4.6 (SV, SE, t) (4.6)
    其中,f 4.1为包含背景噪声的所述监测函数,f 4.2为以所述背景噪声为所述固定分量的函数,f 4.3为含背景噪声的所述扩展分量函数,f 4.4为所述可变分量的传感器函数,f 4.5为所述背景噪声的函数,f 4.6为所述监测值函数,PDN为背景噪声,SE为所述扩展分量的传感器输出信号,SV为所述可变分量的传感器输出信号,t为时间序列; Wherein, f 4.1 is the monitoring function including background noise, f 4.2 is the function with the background noise as the fixed component, f 4.3 is the extended component function including background noise, and f 4.4 is the variable component sensor function, f 4.5 is the function of the background noise, f 4.6 is the monitoring value function, PDN is the background noise, SE is the sensor output signal of the extended component, SV is the sensor output of the variable component signal, t is the time series;
    S4020步骤,根据实际应用,在单一变量监测的情况下,在所述可变分量的传感器的量程满足应用的情况下,采用一个所述可变分量的传感器,在所述可变分量的传感器的量程不满足应用的情况下,采用多个所述可变分量的传感器以延展量程;Step S4020, according to the actual application, in the case of single-variable monitoring, and in the case that the range of the variable-component sensor satisfies the application, adopt one of the variable-component sensors, and in the case of the variable-component sensor If the range does not meet the application, use a plurality of the variable component sensors to extend the range;
    S4030步骤,根据实际应用,在多变量监测的情况下,每个变量采用一个所述可变分量的传感器;Step S4030, according to the actual application, in the case of multi-variable monitoring, each variable adopts a sensor of the variable component;
    S4040步骤,根据实际应用,在所述可变分量的传感器的输出数据满足应用的情况下,不需要采用所述扩展分量的传感器,在所述可变分量的传感器的输出数据不能满足应用的情况下,采用一个以上所述扩展分量的传感器。Step S4040, according to the actual application, if the output data of the variable component sensor satisfies the application, it is not necessary to use the extended component sensor, and in the case that the output data of the variable component sensor cannot meet the application Next, use more than one sensor of the extended component described above.
  5. 根据权利要求2或3或4所述的方法,其特征在于,所述对象算法具体包括:The method according to claim 2, 3 or 4, wherein the object algorithm specifically comprises:
    S5010步骤,采用标准的或者高一级测量精度测量准确度的监测设备,监测获取所述对象的监测值,以此作为所述约定真值,并记录监测的时刻,设定所述约定真值的误差为Δ,且Δ=0,设定所述允许误差为Δ eIn step S5010, standard or higher-level measurement accuracy monitoring equipment is used to monitor and obtain the monitoring value of the object as the agreed true value, record the monitoring time, and set the agreed true value The error is Δ, and Δ=0, and the allowable error is set as Δ e ;
    S5020步骤,设定初始参数集,采用所述当前的监测分量和包括扩展卡尔曼滤波器算法、蒙特卡洛粒子算法、现代贝叶斯算法在内的算法和所述初始参数集,计算所述对象修正值,再与根据所述S5010步骤计算所述约定真值,计算误差,如果所述误差落在所述允 许误差之内,则赋值所述初始参数集为所述个性化参数集,如果所述误差大于所述允许误差,则修改所述初始参数集为所述个性化参数集,使得所述误差落在所述允许误差之内;Step S5020: Set an initial parameter set, and calculate the object correction value, and then calculate the agreed true value according to the step S5010, calculate the error, if the error falls within the allowable error, assign the initial parameter set to the personalized parameter set, if If the error is greater than the allowable error, modify the initial parameter set to be the personalized parameter set, so that the error falls within the allowable error;
    S5030步骤,采用经过所述个性化参数集,采用所述当前的监测分量和包括扩展卡尔曼滤波器算法、蒙特卡洛粒子算法、现代贝叶斯算法在内的算法和所述个性化参数集,计算所述对象修正值;和/或,Step S5030, using the personalized parameter set, using the current monitoring component and algorithms including extended Kalman filter algorithm, Monte Carlo particle algorithm, modern Bayesian algorithm, and the personalized parameter set , calculating the object correction value; and/or,
    S5040步骤,基于设定,采用所述历史的监测分量,依据设定的时间间隔,在所述时间间隔点执行所述S5020步骤,在所述时间间隔点之外,执行所述S5030步骤,建立与所述监测分量对应的个性化参数集和所述时间序列,记录到所述信息库,采用深度学习算法,计算所述信息库中的所述对象的所述监测分量、所述个性化参数集、所述时间序列,找出高概率的所述个性化参数集并标定对应的所述监测分量为优化点,所述高概率包括用户指定概率或概率大于30%的;和/或,Step S5040, based on the setting, using the historical monitoring component, according to the set time interval, execute the step S5020 at the time interval point, and execute the step S5030 outside the time interval point to establish The personalized parameter set and the time series corresponding to the monitoring components are recorded in the information database, and a deep learning algorithm is used to calculate the monitoring components and the personalized parameters of the objects in the information database set and the time series, find out the personalized parameter set with high probability and demarcate the corresponding monitoring component as the optimization point, the high probability includes the user-specified probability or the probability is greater than 30%; and/or,
    S5050步骤,基于所述S5040步骤所获得的所述优化点的所述个性化参数集,采用包括支持向量机算法、卷积神经网络算法,计算所述对象修正值。In step S5050, based on the personalized parameter set of the optimization point obtained in the step S5040, the object correction value is calculated by adopting a support vector machine algorithm and a convolutional neural network algorithm.
  6. 根据权利要求5所述的方法,其特征在于,所述群体算法具体包括:The method according to claim 5, wherein the swarm algorithm specifically comprises:
    S6010步骤,对所述群体中的全部所述对象,计算所述优化点和所述对象修正值,记录到所述信息库;Step S6010, for all the objects in the group, calculate the optimization point and the object correction value, and record them in the information database;
    S6020步骤,依据所述信息库中的所述对象,针对所述优化点和所述对象修正值,建立一个以上的对象分类,并且标定所述对象的所述对象分类,和/或,所述对象分类的个数与所述对象的总数的比值大于用户指定数或者大于0.2,记录到所述信息库;Step S6020, according to the objects in the information database, for the optimization point and the object correction value, establish more than one object classification, and calibrate the object classification of the object, and/or the object classification The ratio of the number of object classifications to the total number of objects is greater than the number specified by the user or greater than 0.2, and is recorded in the information database;
    S6030步骤,依据所述对象分类,对于所述优化点和所述对象修正值,依据误差最小原则,计算所述对象分类的个性化特征集,记录到所述信息库;Step S6030, according to the object classification, for the optimization point and the object correction value, according to the principle of minimum error, calculate the personalized feature set of the object classification, and record it in the information database;
    S6040步骤,依据所述对象分类的个性化特征集,计算所述对象的所述群体修正值;Step S6040, calculating the group correction value of the object according to the personalized feature set of the object classification;
    S6050步骤,对于所述自身对象,计算标定所属于的所述对象分类,依据所述对象分类的个性化特征集,计算所述对象的所述对象修正值和所述群体修正值;Step S6050, for the self-object, calculate the object classification to which the calibration belongs, and calculate the object correction value and the group correction value of the object according to the personalized feature set of the object classification;
    S6060步骤,依据所述对象分类的个性化特征集,对于新加入的所述对象,依据对所述对象的监测值的计算,确定其对象分类,直接采用该分类的所述个性化特征集中包括的所述约定真值,而无需执行监测所述约定真值的步骤;Step S6060, according to the personalized feature set of the object classification, for the newly added object, determine its object classification according to the calculation of the monitoring value of the object, and directly adopt the personalized feature set of the classification to include: said agreed truth value without performing the step of monitoring said agreed truth value;
    所述个性化特征集包括所述对象的所述对象算法的参数、所述群体算法的参数、所述分类和/或所述约定真值。The personalized feature set includes parameters of the object algorithm, parameters of the population algorithm, the classification and/or the agreed truth value for the object.
  7. 根据权利要求5所述的方法,其特征在于,包括差分对象算法,具体如下:The method according to claim 5, characterized in that, comprising a differential object algorithm, the details are as follows:
    S7010步骤,计算所述对象在所述优化点的所述监测值与所述对象修正值的差值,记录到所述信息库;Step S7010, calculating the difference between the monitoring value of the object at the optimization point and the correction value of the object, and recording it in the information database;
    S7020步骤,如果各个所述优化点的所述差值为常数差值,则对于后续时间序列的所述对象修正值,采用所述监测值减去所述常数差值,计算所述对象修正值;和/或,Step S7020, if the difference value of each of the optimization points is a constant difference value, for the object correction value of the subsequent time series, use the monitoring value to subtract the constant difference value to calculate the object correction value ;and / or,
    S7030步骤,如果各个所述优化点的所述差值为函数差值,则对于后续时间序列的所述对象修正值,采用所述监测值减去所述函数差值,计算所述对象修正值;和/或,Step S7030, if the difference value of each optimization point is a function difference value, then for the object correction value of the subsequent time series, subtract the function difference value from the monitoring value to calculate the object correction value ;and / or,
    S7040步骤,如果所述时间序列的所述优化点的所述差值为所述常数差值和所述函数差值的交替差值,采用所述监测值减去所述交替差值,计算所述对象修正值;Step S7040, if the difference value of the optimization point of the time series is an alternating difference value between the constant difference value and the function difference value, subtract the alternating difference value from the monitoring value to calculate the the object correction value;
    S7050步骤,对于拉曼光谱监测的方法,采用两次以上频率具有微小频偏的激发光扫 描所述对象产生两个以上拉曼光谱,依据所述对象的拉曼散射特征位移,对两次以上扫描产生的所述拉曼散射光谱做差分卷积或线性回归计算,以消除由于荧光所带来的背景噪声干扰,所述微小频偏的激发光波长差距在0.2至100nm之间。In step S7050, for the Raman spectrum monitoring method, the object is scanned twice or more with excitation light with a slight frequency offset to generate two or more Raman spectra, and according to the Raman scattering characteristic shift of the object, the two or more The Raman scattering spectrum generated by scanning is calculated by differential convolution or linear regression to eliminate the interference of background noise caused by fluorescence, and the wavelength difference of the excitation light with the slight frequency offset is between 0.2 and 100 nm.
  8. 根据权利要求1所述的方法,其特征在于,所述个性化特征集,具体如下:The method according to claim 1, wherein the personalized feature set is as follows:
    S8010步骤,设定约束条件为所述对象的所述修正值误差小于所述允许误差,按照公式(8.1)建立所述个性化特征集,计算所述个性化特征集:Step S8010, set a constraint condition that the error of the corrected value of the object is less than the allowable error, establish the personalized feature set according to formula (8.1), and calculate the personalized feature set:
    PF=f 8.1(MI,MIF,Δ≤Δ e)  (8.1) PF=f 8.1 (MI, MIF, Δ≤Δ e ) (8.1)
    其中,f 8.1为个性化特征集函数,PF为包括所述对象算法参数、所述群体算法参数、所述约定真值的所述个性化特征集,MI为所述监测值或监测值数据集合,MIF为所述对象修正值或对象修正值集合,Δ为误差,Δ e为允许误差; Wherein, f 8.1 is the personalized feature set function, PF is the personalized feature set including the object algorithm parameters, the population algorithm parameters, and the agreed truth value, MI is the monitoring value or the monitoring value data set , MIF is the object correction value or set of object correction values, Δ is the error, and Δ e is the allowable error;
    S8020步骤,分解所述个性化特征集:Step S8020, decompose the personalized feature set:
    基于指定,将所述个性化特征集分解为一个以上个性化特征集类别,并且将所述个性化特征集类别分解为包括一个以上个性化特征集类别分量;decomposing the personalized feature set into one or more personalized feature set categories, and decomposing the personalized feature set category into one or more personalized feature set category components based on the specification;
    所述个性化特征集与所述个性化特征集类别之间具有公式(8.2)所确定的函数关系:There is a functional relationship determined by formula (8.2) between the personalized feature set and the category of the personalized feature set:
    PF=f 8.2(PFT)  (8.2) PF=f 8.2 (PFT) (8.2)
    其中,f 8.2为所述个性化特征集的类别函数,PFT为所述个性化特征集类别,所述分解包括从便于计算角度的频域分解,还包括从连续时间角度的时域分解; Wherein, f 8.2 is the category function of the personalized feature set, PFT is the category of the personalized feature set, and the decomposition includes frequency domain decomposition from the perspective of ease of calculation, and also includes time domain decomposition from the perspective of continuous time;
    S8030步骤,监测所述个性化特征集类别的时域值:Step S8030, monitoring the time domain value of the personalized feature set category:
    所述个性化特征集类别与所述连续时间序列之间具有公式(8.3)所确定的函数关系,按照公式(8.3)监测所述个性化特征集类别的时域值:There is a functional relationship between the personalized feature set category and the continuous time series determined by formula (8.3), and the time domain value of the personalized feature set category is monitored according to formula (8.3):
    PFT=f 8.3(t)  (8.3) PFT=f 8.3 (t) (8.3)
    其中,f 8.3为个性化特征集类别时域函数,t为所述连续时间序列; Wherein, f 8.3 is the personalized feature set category time domain function, and t is the continuous time series;
    S8040步骤,监测所述个性化特征集类别的特定时刻值:Step S8040, monitor the specific moment value of the personalized feature set category:
    所述个性化特征集类别的所述特定时刻值与所述特定时刻之间具有公式(8.4)所确定的函数关系,按照公式(8.4)监测所述个性化特征集类别的特定时刻值:There is a functional relationship between the specific moment value of the personalized feature set category and the specific moment, and the specific moment value of the personalized feature set category is monitored according to the formula (8.4):
    PFT T=f 8.3(t,t=T)  (8.4) PFT T = f 8.3 (t, t = T) (8.4)
    其中,f 8.3为所述个性化特征集类别时域函数,T为所述特定时刻,PFT T为所述个性化特征集类别在所述特定时刻的特定时刻值; Wherein, f 8.3 is the time domain function of the personalized feature set category, T is the specific moment, and PFT T is the specific moment value of the personalized feature set category at the specific moment;
    S8050步骤,监测个性化特征集类别分量的时域值:Step S8050, monitor the time domain value of the category component of the personalized feature set:
    按照公式(8.5)分解所述个性化特征集类别为一个以上所述个性化特征集类别分量,所述个性化特征集类别分量与所述连续时间序列之间具有公式(8.6)所确定的函数关系,按照公式(8.5)监测所述个性化特征集类别分量的时域值:The personalized feature set category is decomposed into more than one personalized feature set category component according to formula (8.5), and the personalized feature set category component and the continuous time series have the function determined by formula (8.6) relationship, monitor the time domain value of the category component of the personalized feature set according to formula (8.5):
    PFT=f 8.5(PFT 1,PFT 2,…,PFT q)  (8.5) PFT=f 8.5 (PFT 1 , PFT 2 , . . . , PFT q ) (8.5)
    PFT δ=f 8.6(t,1≤δ≤q)        (8.6) PFT δ = f 8.6 (t, 1≤δ≤q) (8.6)
    其中,f 8.5为个性化特征集类别分解函数,f 8.6为个性化特征集类别分量时域函数,PFT 1,PFT 2,…,PFT q为所述个性化特征集类别分量,q为所述个性化特征集类别分量的总数,δ为所述个性化特征集类别分量编号,q、δ均属自然数,且1≤δ≤q,PFT δ为编号为δ的所述个性化特征集类别分量在所述连续时间序列的时域值; Wherein, f 8.5 is the category decomposition function of the personalized feature set, f 8.6 is the time domain function of the category component of the personalized feature set, PFT 1 , PFT 2 , ..., PFT q are the category components of the personalized feature set, and q is the The total number of category components of the personalized feature set, δ is the category component number of the personalized feature set, q and δ are both natural numbers, and 1≤δ≤q, PFT δ is the category component of the personalized feature set numbered δ the time domain value in the continuous time series;
    S8060步骤,监测所述个性化特征集类别分量的特定时刻值。Step S8060: Monitor the specific moment value of the category component of the personalized feature set.
  9. 所述个性化特征集类别分量在所述特定时刻的所述特定时刻值与所述连续时间序列具有公式(8.7)所确定的函数关系,按照公式(8.7)监测所述个性化特征集类别分量在特定时刻的所述特定时刻值:根据权利要求8所述的方法,其特征在于,包括训练所述个性化特征集的数学模型:The specific time value of the category component of the personalized feature set at the specific time has a functional relationship determined by the formula (8.7) with the continuous time series, and the category component of the personalized feature set is monitored according to the formula (8.7). The specific moment value at a specific moment: the method according to claim 8, characterized in that, comprising training a mathematical model of the personalized feature set:
    S9010步骤,模糊优化法:Step S9010, fuzzy optimization method:
    依据下列数学模型,包括模糊方程、模糊偏微分方程、集合方程,优化所述监测值和所述监测分量,获取在优化的情况下的所述对象的最优值,具体包括:According to the following mathematical models, including fuzzy equations, fuzzy partial differential equations, and set equations, the monitoring value and the monitoring component are optimized, and the optimal value of the object under optimization is obtained, specifically including:
    S9011步骤,建立集合:Step S9011, create a set:
    以所述监测值为元素建立监测值集合,记为MIset;A set of monitoring values is established as an element with the monitoring value, denoted as MIset;
    以所述监测分量为元素建立监测分量集合,记为MI αset,α为所述监测分量的编号; Taking the monitoring component as an element to establish a monitoring component set, denoted as MI α set, where α is the numbering of the monitoring component;
    以所述对象为元素建立对象集合,记为PDset;Create an object set with the object as an element, denoted as PDset;
    分解监测值集合为可变值集合和固定值集合;Decompose the monitoring value set into a variable value set and a fixed value set;
    分解可变值集合为可变分量集合,记可变值集合为PDVset,记可变分量集合为PDV βset,β为所述可变分量的编号; Decomposing the variable value set into a variable component set, denoting the variable value set as PDVset, denoting the variable component set as PDV β set, and β being the number of the variable component;
    分解固定值集合为固定分量集合,记固定值集合为PDFset,记固定分量集合为PDF γset,γ为所述固定分量的编号; Decompose the fixed value set into a fixed component set, denote the fixed value set as PDFset, denote the fixed component set as PDF γ set, and γ is the number of the fixed component;
    分解扩展值集合为扩展分量集合,记扩展值集合为PDEset,记扩展值分量集合为
    Figure PCTCN2021092129-appb-100018
    为所述扩展分量的编号;
    Decompose the extended value set as the extended component set, denote the extended value set as PDEset, and denote the extended value component set as
    Figure PCTCN2021092129-appb-100018
    is the number of the extended component;
    以所述个性化特征集类别为元素建立个性化特征集集合,分量个性化特征集集合为个性化特征集分量集合,记个性化特征集集合为PFTset,记个性化特征集分量集合为PFT δset,δ为所述个性化特征集分量的编号; Taking the personalized feature set category as an element to establish a personalized feature set set, the component personalized feature set set is a personalized feature set component set, and the personalized feature set set is recorded as PFTset, and the personalized feature set component set is recorded as PFT δ set, δ is the serial number of the individualized feature set component;
    所述集合包括模糊集合和非模糊集合;the sets include fuzzy sets and non-fuzzy sets;
    S9012步骤,建立截集:Step S9012, create a cut set:
    依据所述数学模型,依次建立集合之间的映射关系,以所述监测值集合和所述监测分量集合为主键进行排序,成为有序集合,并以从大到小进行正排序后取前λ个元素作为有序头截集,以从小到大反排序后取前μ个元素作为有序尾截集,具体如下:According to the mathematical model, the mapping relationship between the sets is established in turn, and the monitoring value set and the monitoring component set are used for sorting as the primary key to become an ordered set, and the first λ is taken after positive sorting from large to small. The elements are used as the ordered head cut set, and the first μ elements are taken as the ordered tail cut set after reverse sorting from small to large, as follows:
    MIset λ={mi|mi监测值正排序号θ≤λ}                        (9.1) MIset λ = {mi|mi monitoring value positive sequence number θ≤λ} (9.1)
    MI αset λ={mi δ|mi α监测分量正排序号θ≤λ}                  (9.2) MI α set λ = {mi δ |mi α monitoring component positive sequence number θ≤λ} (9.2)
    PDset λ={pd|pd对象正排序号θ≤λ}                          (9.3) PDset λ = {pd|pd object positive sorting number θ≤λ} (9.3)
    PDVset λ={pdv|pdv可变值正排序号θ≤λ}                     (9.4) PDVset λ = {pdv|pdv variable value positive sort number θ≤λ} (9.4)
    PDV βset λ={pdv β|pdv β可变分量正排序号θ≤λ}               (9.5) PDV β set λ ={pdv β |pdv β variable component positive sorting number θ≤λ} (9.5)
    PDFset λ={pdf|pdf固定值正排序号θ≤λ}                     (9.6) PDFset λ = {pdf|pdf fixed value positive sort number θ≤λ} (9.6)
    PDF γset λ={pdf γ|pdf γ固定分量正排序号θ≤λ}               (9.7) PDF γ set λ = {pdf γ |pdf γ fixed component positive sorting number θ≤λ} (9.7)
    PDEset λ={pde|pde扩展值正排序号θ≤λ}                     (9.8) PDEset λ = {pde|pde extension value positive sort number θ≤λ} (9.8)
    PDE γset λ={pde γ|pde γ扩展分量正排序号θ≤λ}               (9.9) PDE γ set λ ={pde γ |pde γ extended component positive sorting number θ≤λ} (9.9)
    PFTset λ={pft|pft个性化特征集正排序号θ≤λ}                (9.10) PFTset λ = {pft|pft personalized feature set positive sorting number θ≤λ} (9.10)
    PFT δset λ={pft δ|pft δ个性化特征集分量正排序号θ≤λ}        (9.11) PFT δ set λ ={pft δ |pft δ Personalized feature set component positive sorting number θ≤λ} (9.11)
    MIset μ={mi|mi监测值反排序号η≤μ}                         (9.12) MIset μ = {mi|mi monitoring value inverse order number η≤μ} (9.12)
    MI αset μ={mi δ|mi α监测分量反排序号η≤μ}                   (9.13) MI α set μ = {mi δ |mi α monitoring component reverse order number η≤μ} (9.13)
    PDset μ={pd|pd对象反排序号η≤μ}                           (9.14) PDset μ = {pd|pd object inverse ordering number η≤μ} (9.14)
    PDVset μ={pdv|pdv可变值反排序号η≤μ}                      (9.15) PDVset μ = {pdv|pdv variable value reverse order number η≤μ} (9.15)
    PDV βset μ={pdv β|pdv β可变分量反排序号η≤μ}                (9.16) PDV β set μ ={pdv β |pdv β variable component inverse order number η≤μ} (9.16)
    PDFset μ={pdf|pdf固定值反排序号η≤μ}                       (9.17) PDFset μ = {pdf|pdf fixed value inverse sort number η≤μ} (9.17)
    PDF γset μ={pdf γ|pdf γ固定分量反排序号η≤μ}                 (9.18) PDF γ set μ = {pdf γ |pdf γ fixed component inverse ordering number η≤μ} (9.18)
    PDEset μ={pde|pde扩展值反排序号η≤μ}                       (9.19) PDEset μ = {pde|pde extension value inverse sort number η≤μ} (9.19)
    PDE γset μ={pde γ|pde γ扩展分量反排序号η≤μ}                (9.20) PDE γ set μ = {pde γ |pde γ extended component inverse ordering number η≤μ} (9.20)
    PFTset μ={pft|pft个性化特征集反排序号η≤μ}                 (9.21) PFTset μ = {pft|pft personalized feature set inverse order number η≤μ} (9.21)
    PFT δset μ={pft δ|pft γ个性化特征集分量反排序号η≤μ}         (9.22) PFT δ set μ ={pft δ |pft γ personalized feature set component inverse order number η≤μ} (9.22)
    其中,MIset λ、MI αset λ、PDset λ、PDVset λ、PDV βset λ、PDFset λ、PDF γset λ、PDEset λ、PDE γset λ、PFTset λ、PFT δset λ为所述有序头截集,MIset μ、MI αset μ、PDset μ、PDVset μ、PDV βset μ、PDFset μ、PDF γset μ、PDEset μ、PDE γset μ、PFTset μ、PFT δset μ为所述有序尾截集,λ、μ为小于各自集合元素个数,也就是所述截集位置,属于自然数,θ为正排序编号,η为反排序编号; Wherein, MIset λ , MI α set λ , PDset λ , PDVset λ , PDV β set λ , PDFset λ , PDF γ set λ , PDEset λ , PDE γ set λ , PFTset λ , PFT δ set λ are the ordered heads Cut set, MIset μ , MI α set μ , PDset μ , PDVset μ , PDV β set μ , PDFset μ , PDF γ set μ , PDEset μ , PDE γ set μ , PFTset μ , PFT δ set μ are the ordering Tail cut set, λ and μ are less than the number of elements in their respective sets, that is, the position of the cut set, which belongs to a natural number, θ is the positive sorting number, and η is the reverse sorting number;
    S9013步骤,训练所述截集:Step S9013, train the cutout:
    持续监测记录所述监测值和所述对象到所述信息库,依据所述信息库中的信息,采用循环和递归计算,以训练所述有序头截集和所述有序尾截集,记录结果到所述信息库;Continuously monitor and record the monitoring value and the object to the information base, and according to the information in the information base, adopt cyclic and recursive calculation to train the ordered head cut set and the ordered tail cut set, record the results to the repository;
    S9014步骤,寻优所述截集:Step S9014, search for optimization of the interception set:
    依据所述数学模型,按照公式(9.1)至公式(9.22),取λ=1,计算获取监测值最优值和监测分量最优值,所对应的所述对象同时作为最优值;取μ=1,计算获取监测值最差值和监测分量最差值,所对应的所述对象同时作为最差值;和/或,According to the mathematical model, according to formula (9.1) to formula (9.22), take λ=1, calculate and obtain the optimal value of the monitoring value and the optimal value of the monitoring component, and the corresponding object is also used as the optimal value; take μ =1, calculate and obtain the worst value of the monitoring value and the worst value of the monitoring component, and the corresponding object is simultaneously regarded as the worst value; and/or,
    S9020步骤,建立偏微分模型:Step S9020, establish a partial differential model:
    采用偏微分方程原理,按照公式(9.23)和公式(9.24)建立所述监测值、所述监测分量和所述可变分量、所述固定分量、所述扩展分量之间的函数,计算所述监测值、所述监测分量:Using the principle of partial differential equations, according to formula (9.23) and formula (9.24), establish functions between the monitoring value, the monitoring component, the variable component, the fixed component, and the extended component, and calculate the Monitoring value, the monitoring component:
    Figure PCTCN2021092129-appb-100019
    Figure PCTCN2021092129-appb-100019
    Figure PCTCN2021092129-appb-100020
    Figure PCTCN2021092129-appb-100020
    其中:in:
    f 9.23、f 9.24均是偏微分方程,MI′ 1是编号为1的所述监测分量的1阶导数,
    Figure PCTCN2021092129-appb-100021
    是编号为1所述监测分量的ε阶导数,MI′ m是编号为m的所述监测分量的1阶导数,
    Figure PCTCN2021092129-appb-100022
    是编号为m的所述监测分量的ε阶导数;PDV′ α是第α种包括一个以上与所述MI α有关联的所述可变分量的1阶导数;
    Figure PCTCN2021092129-appb-100023
    是第α种包括一个以上与所述MI α有关联的所述可变分量的v阶导数;PDF′ α是第α种包括零个以上与所述MI α有关联的所述固定分量的1阶导数;
    Figure PCTCN2021092129-appb-100024
    是第α种包括零个以上与所述MI α有关联的所述固定分量的v阶导数;PDE′ α是第α种包括零个以上与所述MI α有关联的所述扩展分量的1阶导数;
    Figure PCTCN2021092129-appb-100025
    是第α种包括零个以上与所述MI α有关联的所述可变分量的ξ阶导数;PFT′ α是第α种包括零个以上与所述MI α有关联的所述扩展分量的1阶导数;
    Figure PCTCN2021092129-appb-100026
    是第α种包括零个以上与所述MI α有关联的所述个性化特征集类别分量的∈阶导数;
    Both f 9.23 and f 9.24 are partial differential equations, MI′ 1 is the first derivative of the monitoring component numbered 1,
    Figure PCTCN2021092129-appb-100021
    is the ε order derivative of the monitoring component numbered 1, MI′ m is the first order derivative of the monitoring component numbered m,
    Figure PCTCN2021092129-appb-100022
    is the ε-order derivative of the monitoring component numbered m; PDV'α is the α -th first-order derivative of the variable component that includes more than one associated with the MI α ;
    Figure PCTCN2021092129-appb-100023
    is the αth derivative of the v-th order including more than one of the variable components associated with the MI α ; PDF' α is the αth 1 including zero or more of the fixed components associated with the MI α order derivative;
    Figure PCTCN2021092129-appb-100024
    is the α-th derivative of the v-th order including zero or more of the fixed components associated with the MI α ; PDE'α is the α -th 1 including zero or more of the extended components associated with the MI α order derivative;
    Figure PCTCN2021092129-appb-100025
    is the α -th derivative of the variable component including zero or more of the variable components associated with the MI α ; PFT′α is the 1st derivative;
    Figure PCTCN2021092129-appb-100026
    is the αth derivative of the ε order that includes zero or more of the category components of the personalized feature set associated with the MI α ;
    其中,根据需要,函数f 9.23中的所述监测分量还采用f 9.24中的MI α替代; Wherein, as required, the monitoring component in function f 9.23 is also replaced by MI α in f 9.24 ;
    其中,ε是所述监测分量导数的最高阶,v是所述可变分量导数的最高阶,ξ是所述扩展分量导数的最高阶,ε、v、ξ、∈均是自然数;Wherein, ε is the highest order of the monitored component derivative, v is the highest order of the variable component derivative, ξ is the highest order of the extended component derivative, and ε, v, ξ, and ε are all natural numbers;
    S9030步骤,极值优化法:Step S9030, extreme value optimization method:
    依据所述偏微分方程和所述模糊偏微分方程,采用对包括公式(9.23)、公式(9.24)的所述偏微分方程中的自变量、因变量取极值的方法,以及求取任意所述自变量、所述因变量为0的时候,计算所述监测值和所述监测分量的方法,获取所述监测值和所述监测分量的所述最优值和所述最差值,以此获取所述对象的最优值;According to the partial differential equation and the fuzzy partial differential equation, the method of taking extreme values of the independent variable and the dependent variable in the partial differential equation including formula (9.23) and formula (9.24), and obtaining any When the independent variable and the dependent variable are 0, the method of calculating the monitoring value and the monitoring component is obtained, and the optimal value and the worst value of the monitoring value and the monitoring component are obtained to obtain This gets the optimal value of the object;
    S9031步骤,依据所述信息库随着时间推移而不断地更新,在定时或不定时情况下,实现多次学习和训练,采用包括T检验和Z检验的方法选出所述监测值和所述监测分量的所述最优值和所述监测值和所述监测分量的所述最差值的异常值,消除所述异常值,以此获取所述对象的异常值;和/或,In step S9031, according to the information base being continuously updated over time, in timed or irregular conditions, multiple learning and training are implemented, and methods including T test and Z test are used to select the monitoring value and the said monitoring value. monitoring the optimal value of the component and the abnormal value of the monitoring value and the worst value of the monitoring component, eliminating the abnormal value, thereby obtaining the abnormal value of the object; and/or,
    S9040步骤,概率优化法:Step S9040, probability optimization method:
    在所述信息库中,选取不同时间段采集的所述对象监测值和所述对象扩展分量,计算所述监测值和所述监测分量,计算所述监测值和所述监测分量为最大值和最小值时对应的所述对象,采用包括贝叶斯算法在内的概率计算方法,统计所述监测值和所述监测分量为最大值和最小值时,所述对象中所述可调对象监测值和所述可调对象扩展分量出现相近值的概率,并对高概率验证做验证;和/或,In the information base, the object monitoring value and the object extension component collected in different time periods are selected, the monitoring value and the monitoring component are calculated, and the monitoring value and the monitoring component are calculated as the maximum value and the When the object corresponding to the minimum value, the probability calculation method including the Bayesian algorithm is used, and when the statistics of the monitoring value and the monitoring component are the maximum value and the minimum value, the adjustable object in the object is monitored. The probability that the value and the extended component of the adjustable object have similar values, and verify the high probability verification; and/or,
    标定在所述监测值和所述监测分量为最大值时的所述对象中所述可调对象监测值和所述可调对象扩展分量为优化可调对象监测值和优化可调对象扩展分量,标定在所述监测值和所述监测分量为最小值时的所述对象中所述可调对象监测值和所述可调对象扩展分量为劣化可调对象监测值和劣化可调对象扩展分量;和/或,Calibrating the adjustable object monitoring value and the adjustable object extension component in the object when the monitoring value and the monitoring component are maximum values are the optimized adjustable object monitoring value and the optimized adjustable object extension component, Calibrating the adjustable object monitoring value and the adjustable object extension component in the object when the monitoring value and the monitoring component are minimum values to be a degraded adjustable object monitoring value and a degraded adjustable object extension component; and / or,
    S9050步骤,神经网络优化法:Step S9050, neural network optimization method:
    S9051步骤,依据包括所述数学模型,针对所述信息库中的关系型信息记录,以信息记录作为神经元,以包括所述数学模型的计算结果建立所述神经元之间的连接函数,构成一层以上的神经网络;Step S9051, according to including the mathematical model, for the relational information records in the information base, using the information records as neurons, and establishing a connection function between the neurons with the calculation results including the mathematical model, forming More than one layer of neural network;
    S9052步骤,依据所述连接函数中,所述优化可调对象监测值和优化可调对象扩展分量对于所述监测值和所述监测分量产生的效果,划分和建立兴奋型、抑制型、爆发型、平台期型的连接子函数,所述连接子函数包括常数型权重系数、函数型权重系数;Step S9052, according to the connection function, according to the effect of the optimized adjustable object monitoring value and the optimized adjustable object extended component on the monitored value and the monitored component, divide and establish an excitatory type, an inhibitory type, and an explosive type. , a platform-type linker function, and the linker function includes a constant-type weight coefficient and a function-type weight coefficient;
    S9053步骤,采用深度学习算法,包括监督学习、无监督学习、强化学习算法,优化所述连接子函数;和/或,Step S9053, using deep learning algorithms, including supervised learning, unsupervised learning, and reinforcement learning algorithms, to optimize the connection sub-function; and/or,
    S9054步骤,采用支持向量机算法,分类筛选所述监测值和所述监测分量,并且筛选出所述优化可调对象监测值和优化可调对象扩展分量;和/或,Step S9054, adopting a support vector machine algorithm to classify and screen the monitoring value and the monitoring component, and screen out the optimized adjustable object monitoring value and the optimized adjustable object extended component; and/or,
    S9055步骤,采用卷积神经网络算法,对于所述对象之间忽略关联的条件下,实施卷积、激活、池化、全连接、训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量;和/或,Step S9055, using a convolutional neural network algorithm, for the condition of ignoring the association between the objects, implementing convolution, activation, pooling, full connection, and training the connection sub-function to filter out the monitoring including optimization. value and said monitored component; and/or,
    S9056步骤,采用循环神经网络算法,对于所述对象之间需要关联的条件下,建立层内关联函数,训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量;和/或,Step S9056, adopting a cyclic neural network algorithm, under the condition that the objects need to be correlated, establish an intra-layer correlation function, and train the linker function to filter out the monitoring value and the monitoring component including optimization; and / or,
    S9057步骤,采用深度神经网络算法,对于各个所述神经网络的层之间的所述对象、所述监测值、所述监测分量需要建立关联的条件下,建立层间关联函数,训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量;和/或,In step S9057, a deep neural network algorithm is used to establish an inter-layer correlation function under the condition that the object, the monitoring value and the monitoring component between the layers of the neural network need to be correlated, and the connection is trained. a sub-function to filter out said monitoring value and said monitoring component including optimization; and/or,
    S9058步骤,采用前馈神经网络算法,对于所述每个神经元只与前一层的神经元相连的条件下,训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量;和/或,In step S9058, a feedforward neural network algorithm is used to train the connection sub-function under the condition that each neuron is only connected to the neurons of the previous layer, so as to filter out the monitoring value including the optimized monitoring value and the monitor the amount; and/or,
    S9059步骤,采用反馈神经网络算法,对于所述每个神经元只与后一层的神经元相连的条件下,训练所述连接子函数,以筛选出包括优化的所述监测值和所述监测分量;和/或,In step S9059, a feedback neural network algorithm is used to train the connection sub-function under the condition that each neuron is only connected to the neuron of the next layer, so as to filter out the monitoring value including the optimized monitoring value and the monitoring value. amount; and/or,
    S9060步骤,可逆寻优法:Step S9060, reversible optimization method:
    采用所述模糊优化法、所述极值优化法、所述概率优化法、所述神经网络优化法之间的任意组合和/或这些方法之内的任意组合的方法,计算所述监测值和所述监测分量达到最优或者其区间内的指定值时,使得结果信息能够可逆复现所述监测值和所述监测分量达到最优或者其区间内的指定值,所述监测分量之间的可逆关系;和/或,The monitoring value and When the monitoring component reaches the optimum or the specified value within its interval, the result information can reversibly reproduce the monitoring value and the monitoring component reaches the optimum or the specified value within the interval, and the difference between the monitoring components is reversible. reversible relationship; and/or,
    S9070步骤,定时复现法:Step S9070, timing repetition method:
    依据所述数学模型和所述可逆关系,计算从当前时刻开始,所述监测值和/或所述监测分量到达优化值或者指定值时的定时时间序列值,即从当前时刻开始,经过所述定时时间序列值的时间时,所述监测值和/或所述监测分量到达优化值或者指定值;和/或,According to the mathematical model and the reversible relationship, calculate the timing time series value when the monitoring value and/or the monitoring component reach the optimal value or the specified value starting from the current moment, that is, starting from the current moment, after the When the time of the time series value is timed, the monitored value and/or the monitored component reaches an optimized value or a specified value; and/or,
    S9080步骤,延时复现法:Step S9080, delay reproduction method:
    依据所述数学模型和所述可逆关系,当所述定时时间序列值小于预定健康考核时域值的情况下,计算需要延时时间差值,将所述延时时间差值加入到所述数学模型,以确保在所述预定健康考核时间的时点,所述监测值和/或所述监测分量到达优化值或者指定值。According to the mathematical model and the reversible relationship, when the timing time series value is less than the predetermined health assessment time domain value, calculate the required delay time difference, and add the delay time difference to the mathematical model. A model is used to ensure that the monitoring value and/or the monitoring component reaches an optimal value or a specified value at the time point of the predetermined health assessment time.
    PFT δT=f 8.6(t,t=T,1≤δ≤q)  (8.7) PFT δT = f 8.6 (t, t=T, 1≤δ≤q) (8.7)
    其中,PFT δT为在所述特定时刻所述个性化特征集类别分量的所述特定时刻值。 Wherein, PFT δT is the specific time value of the category component of the personalized feature set at the specific time.
  10. 根据权利要求1所述的方法,其特征在于,包括:The method of claim 1, comprising:
    SA100步骤,云大数据模式:SA100 steps, cloud big data model:
    SA110步骤,建立基于互联网模式的云中心,将本发明所监测的包括全部所述群体、所述对象的全部信息、中间计算结果、所述信息库,以云终端形式通过广域网网络传输,全部存储到基于互联网的一个以上云服务器上,以此作为一个以上云中心,采用云计算模式管理、计算和支撑所述云终端;和/或,In step SA110, a cloud center based on the Internet model is established, and all information monitored by the present invention, including all the groups, all the information of the objects, the intermediate calculation results, and the information base, are transmitted through the wide area network network in the form of cloud terminals, and all stored to one or more Internet-based cloud servers as one or more cloud centers to manage, calculate and support the cloud terminals in a cloud computing mode; and/or,
    SA120步骤,采用区块链模式建立一个以上云中心,以存储、管理和支撑所述信息库和前述的各个步骤,所述用户采用匿名记录,所述信息库中的信息采用带有时间戳的链式结构,用户访问所述信息库采用加解密通信,信息支持防篡改,支持防抵赖、多中心、无中心模式;和/或,In step SA120, one or more cloud centers are established in the blockchain mode to store, manage and support the information base and the aforementioned steps. The users use anonymous records, and the information in the information base uses timestamped Chain structure, users access the information base through encryption and decryption communication, the information supports anti-tampering, supports anti-repudiation, multi-center, and no-center modes; and/or,
    SA130步骤,采用安全多方计算模式建立和管理和支撑一个以上机构,在所述机构之间,在不交换所述机构所属各自的所述云中心的所述信息库核心信息的前提下,依据各自所述机构的所述信息库内容进行约定的计算,所得的计算结果由参与的所述机构共享;所述机构包括一个以上所述云中心,管理一个以上所述对象;所述安全多方计算包括:公开密钥机制、混合电路、不经意传输、秘密共享、隐私保护集合交集协议、同态加密、零知 识证明、无可信中心的方法,以增强信息的安全性和保护对象隐私;和/或,In step SA130, a secure multi-party computing model is used to establish, manage and support more than one organization. The content of the information base of the organization performs the agreed calculation, and the obtained calculation result is shared by the participating organizations; the organization includes one or more of the cloud centers and manages more than one of the objects; the secure multi-party computing includes : public key mechanisms, hybrid circuits, inadvertent transmission, secret sharing, privacy-preserving set intersection protocols, homomorphic encryption, zero-knowledge proofs, methods without trusted centers to enhance information security and protect object privacy; and/or ,
    SA140步骤,采用集中学习模式建立和训练对于不强调对象隐私保护时的模型训练,所述信息库存储于一个云中心;和/或,In step SA140, the centralized learning mode is used to establish and train the model training when the object privacy protection is not emphasized, and the information database is stored in a cloud center; and/or,
    S9150步骤,采用联邦学习模式建立和训练对于需要强调对象隐私保护时的模型训练,此时的所述模型训练在一个以上存储的云中心之间进行,各个所述云中心之间不交换各自的信息;和/或,In step S9150, the federated learning mode is used to establish and train the model training when the privacy protection of the object needs to be emphasized. At this time, the model training is performed between more than one stored cloud center, and the respective cloud centers do not exchange their respective cloud centers. information; and/or,
    SA200步骤,局域网模式:SA200 steps, LAN mode:
    建立基于局域网的服务器用于存储和管理支撑中心,将本发明所监测的包括全部群体、对象的全部信息、中间计算结果、所述信息库,以网络终端形式通过局域网网络传输,全部存储到基于局域网的服务器上,以此管理、计算和支撑;和/或,A local area network-based server is established to store and manage the support center, and all information including all groups and objects, intermediate calculation results, and the information base monitored by the present invention are transmitted through the local area network network in the form of network terminals, and all stored in the servers in the local area network for management, computing and support; and/or,
    SA300步骤,单点模式:SA300 steps, single point mode:
    所述单点为监测一个所述对象的监测、存储、管理、计算和支撑的步骤,将本发明所监测的对象的全部信息、中间计算结果、所述信息库,全部存储到所述单点的存储上,执行全部步骤。The single point is to monitor the steps of monitoring, storage, management, calculation and support of one of the objects, and all the information of the object monitored by the present invention, the intermediate calculation results, and the information base are all stored in the single point. storage, perform all steps.
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