WO2022217875A1 - 一种多剂量可调预充注射笔 - Google Patents

一种多剂量可调预充注射笔 Download PDF

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Publication number
WO2022217875A1
WO2022217875A1 PCT/CN2021/124591 CN2021124591W WO2022217875A1 WO 2022217875 A1 WO2022217875 A1 WO 2022217875A1 CN 2021124591 W CN2021124591 W CN 2021124591W WO 2022217875 A1 WO2022217875 A1 WO 2022217875A1
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WO
WIPO (PCT)
Prior art keywords
dose
injection
hub
push rod
pen
Prior art date
Application number
PCT/CN2021/124591
Other languages
English (en)
French (fr)
Inventor
倪世利
孙小峰
徐千贺
李文政
李志飞
Original Assignee
山东威高普瑞医药包装有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202120784042.4U external-priority patent/CN215083461U/zh
Priority claimed from CN202110411143.1A external-priority patent/CN113144341A/zh
Application filed by 山东威高普瑞医药包装有限公司 filed Critical 山东威高普瑞医药包装有限公司
Priority to EP21936742.2A priority Critical patent/EP4324500A1/en
Priority to US18/271,435 priority patent/US20240058544A1/en
Priority to BR112023015609A priority patent/BR112023015609A2/pt
Publication of WO2022217875A1 publication Critical patent/WO2022217875A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback

Definitions

  • the present invention relates to the technical field of injection equipment, and more particularly, to a multi-dose adjustable prefilled injection pen.
  • the current injection pen product has a complex structure, a large number of parts, and many processing procedures, resulting in low product reliability; some products use gluing to bond parts and components in the process of processing, which has biological risks; product parts involve There are many metal products, resulting in an increase in product cost, and the use effect is not good.
  • the purpose of the present invention is to provide a multi-dose adjustable pre-filled injection pen, which can effectively solve the problems of inconvenient operation and poor dose adjustment effect of the current injection pen.
  • the present invention provides the following technical solutions:
  • a multi-dose adjustable pre-filled injection pen comprising a pen body, an injection push rod, a push rod sleeve, a clutch hub, an end stopper and a dose hub, the injection push rod and the pen body extending in an axial direction
  • the push rod sleeve and the injection push rod are slidingly matched along the injection direction and can transmit the torque in the screwing direction of the injection push rod.
  • the two are connected by a first group of ratchets and pawls to prevent the push rod sleeve from rotating relative to the pen body around the injection push rod in the direction of retraction, and the clutch hub and the push rod sleeve rotate along the injection push rod.
  • the direction is sliding fit and the relative rotation is limited, the dose hub and the pen body are connected through a screw thread and can push the dose hub to screw in when the dose hub is axially driven, and the clutch hub is between the dose hub and the dose hub.
  • Rotation is restricted by a snap-fit structure that can be disengaged along the injection direction, the end stopper and the dose hub are supported by support feet that can be elastically deformed along the injection direction, and the end stopper is subject to
  • the injection direction thrust is used to elastically deform the supporting feet, the clamping structure can be prevented from being disengaged, and the dose hub can be rotated before the supporting feet are elastically deformed to push the clamping structure to disengage. Card access.
  • the cartridge when in use, the cartridge is fixed on the pen body, and then the injection push rod is abutted against the rubber stopper of the cartridge, and the dose hub is at the initial position relative to the pen body. Location. Then push the end stopper along the injection direction to elastically deform the supporting foot, and then prevent the snap-fit structure from being released from the snap-fit. At this time, the end stopper transmits the thrust in the injection direction to the dose hub, and the dose hub will screw in. Because the clamping structure is clamped at this time, the dose hub will drive the clutch hub to rotate, so as to drive the push rod sleeve to rotate in turn. The plunger turns to inject. When the first injection is completed, release the end stop and reset the end stop.
  • the dose hub returns to its original position to facilitate re-adjustment of the dose for the next injection.
  • the dose hub can be operated and unscrewed relative to the pen body.
  • the dose hub cannot drive the clutch hub to rotate, but drives the clutch hub along the injection direction.
  • the reverse sliding of the injection push rod and the push rod sleeve is not moving relative to the pen body at this time.
  • an end stopper is provided, and the rotational connection between the dose hub and the clutch hub is controlled through the elastic support feet, so that when injecting, the end is directly pressed.
  • the stopper can complete the injection, and when rotating the dose adjustment, it is only necessary to rotate the dose hub alone, which makes the operation very convenient and simple, and the dose adjustment operation is simple, and the overall structure is very simple, with few parts, convenient assembly, and no need to use Structures such as metal springs make the overall cost lower.
  • the multi-dose adjustable prefilled injection pen can effectively solve the problems of inconvenient operation and poor dose adjustment effect of the current injection pen.
  • a dose limiting nut is also included, the dose limiting nut is connected with the clutch hub through threads, and is slidably fitted with the dose hub along the injection direction and restricts relative rotation, so that the dose hub is opposite to the clutch hub when the dose hub is in contact with the clutch hub. When rotating, it moves in the axial direction of the clutch hub.
  • the tip of the support foot is a pawl
  • the end of the dose hub has ratchet teeth matched with the pawl on the support foot to prevent relative rotation in the precession direction; the end is limited to
  • the position member has a limit flange
  • the dose hub is correspondingly provided with a limit groove surrounded on the limit flange, so as to limit the movement range of the limit flange in the injection direction.
  • the rear end of the clutch hub has a convex plate
  • the front side of the convex plate has a plurality of arc-shaped protrusions evenly distributed in the circumferential direction
  • the rear end of the dose hub has an annular shoulder
  • the rear of the annular shoulder The side has arc-shaped tooth grooves distributed circumferentially and matched with the arc-shaped protrusions; the rear end of the clutch hub and the end limiter are connected through a second group of ratchet-tooth-and-pawl mechanisms.
  • the end button also includes an end button, the periphery of the end button is clamped on the end stopper, and the middle part has a force transmission cylinder extending along the injection direction, and the front end of the force transmission cylinder is connected to the end
  • the limiting pieces are in contact with each other and are spherical.
  • the pen body comprises a barrel and a push rod nut that is clamped into the barrel, the push rod nut is threadedly connected with the injection push rod, and the push rod sleeve passes through the first set of ratchets Tooth and pawl mechanism connection.
  • the injection push rod, the push rod sleeve, the clutch hub, the dose limiting nut, the dose hub and the barrel are sleeved in sequence.
  • the pen body has a window
  • the outer side of the dose hub has a spirally distributed scale to be able to pass through the window in sequence during precession.
  • it also includes a medicine bottle holder that is clamped at the front end of the body tube, the back end of the medicine bottle holder has a medicine bottle ring, and the front end of the medicine bottle ring is used to abut against the medicine bottle in the medicine bottle holder,
  • the front end of the injection push rod is in contact with the pen body, the front end of the injection push rod has a push rod knob that can be rotated to abut against the rubber stopper of the medicine bottle, and the front end of the medicine bottle holder has a threaded post for connecting the needle.
  • a pen cap is also included, and the rear end of the pen cap is clamped to the medicine bottle holder.
  • FIG. 1 is a schematic cross-sectional structure diagram of a multi-dose adjustable pre-filled injection pen provided by an embodiment of the present invention
  • FIG. 2 is a schematic diagram of an explosion structure of a multi-dose adjustable pre-filled injection pen provided by an embodiment of the present invention
  • FIG. 3 is a schematic diagram of the external structure of the multi-dose adjustable pre-filled injection pen provided by the embodiment of the present invention after the pen cover is removed;
  • FIG. 4 is a schematic structural diagram of a multi-dose adjustable pre-filled injection pen dose hub being unscrewed according to an embodiment of the present invention
  • FIG. 5 is a schematic cross-sectional structural diagram of a multi-dose adjustable pre-filled injection pen dose hub being unscrewed according to an embodiment of the present invention
  • FIG. 6 is a schematic structural diagram of a push rod nut provided by an embodiment of the present invention.
  • FIG. 7 is a schematic structural diagram of a dose limiting nut provided by an embodiment of the present invention.
  • FIG. 8 is a schematic structural diagram of a clutch hub provided by an embodiment of the present invention.
  • FIG. 9 is a schematic structural diagram of a push rod sleeve provided by an embodiment of the present invention.
  • FIG. 10 is a schematic structural diagram of an end stopper provided by an embodiment of the present invention.
  • FIG. 11 is a schematic structural diagram of a medicine bottle holder provided by an embodiment of the present invention.
  • FIG. 12 is a schematic structural diagram of a dose hub provided by an embodiment of the present invention.
  • FIG. 13 is a schematic diagram of the internal structure of the opening of the barrel provided by an embodiment of the present invention.
  • FIG. 14 is a schematic diagram of a rear end structure of a multi-dose adjustable pre-filled injection pen provided by an embodiment of the present invention.
  • FIG. 15 is a schematic diagram of a rear end explosion structure of a multi-dose adjustable prefilled injection pen provided by an embodiment of the present invention.
  • FIG. 16 is a schematic diagram of a rear cross-sectional structure of a multi-dose adjustable prefilled injection pen provided by an embodiment of the present invention.
  • 17 is a schematic diagram of the installation between the clutch hub and the dose hub provided by the embodiment of the present invention.
  • FIG. 18 is a schematic diagram of a rear end installation cross-sectional structure of a multi-dose adjustable prefilled injection pen provided by an embodiment of the present invention.
  • Fig. 19 is a schematic diagram of the installation structure between the dose limiting nut and the dose hub provided by the embodiment of the present invention.
  • the embodiment of the present invention discloses a multi-dose adjustable pre-filled injection pen, so as to effectively solve the problems of inconvenient operation and poor dose adjustment effect of the current injection pen.
  • FIG. 1 is a schematic cross-sectional structure diagram of a multi-dose adjustable pre-filled injection pen provided by an embodiment of the present invention
  • FIG. 2 is an explosion structure of the multi-dose adjustable pre-filled injection pen provided by an embodiment of the present invention.
  • Schematic diagram
  • Figure 3 is a schematic diagram of the external structure of the multi-dose adjustable pre-filled injection pen provided by the embodiment of the present invention after the pen cover is removed
  • Figure 4 is the multi-dose adjustable pre-filled injection pen provided by the embodiment of the present invention.
  • FIG. 5 is a schematic diagram of the cross-sectional structure of the multi-dose adjustable pre-filled injection pen dose hub provided by the embodiment of the present invention
  • FIG. 6 is a schematic diagram of the structure of the push rod nut provided by the embodiment of the present invention. Schematic diagram of the structure of the dose limiting nut provided by the embodiment of the present invention.
  • FIG. 8 is the schematic structural diagram of the clutch hub provided by the embodiment of the present invention.
  • FIG. 9 is the schematic structural diagram of the push rod sleeve provided by the embodiment of the present invention.
  • Figure 11 is a schematic structural diagram of a medicine bottle holder provided by an embodiment of the present invention.
  • Figure 12 is a schematic structural schematic diagram of a dose hub provided by an embodiment of the present invention;
  • Figure 14 is a schematic diagram of the rear end structure of the multi-dose adjustable pre-filled injection pen provided by the embodiment of the present invention;
  • Figure 15 is the rear end of the multi-dose adjustable pre-filled injection pen provided by the embodiment of the present invention.
  • FIG. 16 Schematic diagram of the end explosion structure
  • Figure 16 is a schematic diagram of the rear end cross-sectional structure of the multi-dose adjustable prefilled injection pen provided by the embodiment of the present invention
  • Figure 17 is a schematic diagram of the installation between the clutch hub and the dose hub provided by the embodiment of the present invention
  • Figure 18 is a schematic diagram of the rear end installation structure of the multi-dose adjustable prefilled injection pen provided by the embodiment of the present invention
  • FIG. 19 is a schematic diagram of the installation structure between the dose limiting nut and the dose hub provided by the embodiment of the present invention.
  • this implementation provides a multi-dose adjustable pre-filled injection pen, as shown in Figures 1-3 , the multi-dose adjustable pre-filled injection pen mainly includes a pen body and an injection push rod 13 , push rod sleeve 7, clutch hub 6, end limiter 8 and dose hub 14, of course, can also be provided with a medicine bottle holder 10 for placing the cartridge 2, a pen cap 9 sleeved on the pen body, etc. .
  • the injection push rod 13 and the pen body are connected by a thread whose axis extending direction is the injection direction, so that when the injection push rod 13 rotates in the screwing direction, the injection push rod 13 will move in an axial direction relative to the pen body, and because The cartridge bottle 2 and the pen body are relatively fixed.
  • the relative fixing is achieved by the medicine bottle holder 10.
  • the relative fixing can also be achieved by connection methods such as clip connection and screw connection. Therefore, the injection push rod 13 can push the rubber stopper 3 inside the cartridge 2 to move along the injection direction, that is, injection is formed.
  • the push rod sleeve 7 and the injection push rod 13 are slidably matched along the injection direction and can transmit the torque in the precession direction of the injection push rod.
  • the injection push rod 13 is provided with an external thread, then one side or opposite sides of the injection push rod 13 can be flattened, and the push rod sleeve 7 is sleeved on the outside of the injection push rod 13, and the cross section is set correspondingly, that is, Correspondingly, a flattened flat surface 71 is provided to restrict the rotation of the inner injection push rod 13 , but the injection push rod 13 can slide along the injection direction in the push rod sleeve 7 to realize sliding connection.
  • the injection push rod 13 can also be provided with an axially extending groove, and the inner side of the push rod sleeve 7 is provided with a corresponding convex strip, so as to restrict the push rod sleeve 7 from being opposite to the injection push rod 13 through the convex strip groove. turn.
  • the push rod sleeve 7 and the pen body are connected by a first group of ratchet pawl mechanisms to prevent the push rod sleeve 7 from rotating relative to the pen body around the injection push rod 13 , and the clutch hub 6 and the push rod sleeve
  • the barrel 7 is slidably fitted along the injection direction and restricts relative rotation. Because the relative rotation between the push rod sleeve 7 and the injection push rod 13 is restricted, the injection push rod 13 can be prevented from rotating in the reverse direction, so that the push rod sleeve 7 , the injection push rod 13 and the clutch hub 6 can only rotate around the injection push rod 6 .
  • the push rod 13 rotates in the precession direction, and the injection push rod 13 performs injection at this time.
  • the push rod sleeve 7 rotates along with it, but is relatively fixed to the pen body in the injection direction. At this time, the injection push rod 13 slides relative to the push rod sleeve 7 along the injection direction.
  • the clutch hub 6 and the push rod sleeve 7 are slidably matched along the injection direction and restrict relative rotation.
  • the clutch hub 6 can be sleeved on the outside of the push rod sleeve 7, and the outer side of the push rod sleeve 7 and the clutch In the inner side of the hub 6, one is provided with a protruding strip extending along the injection direction, and the other is provided with a groove matching the protruding strip to limit relative rotation.
  • a groove 73 is provided with first protruding strips 61 on opposite sides of the clutch hub 6 .
  • the dose hub 14 is connected with the pen body through screw rotation, and when the dose hub 14 is driven axially, it can push the dose hub 14 to screw in, that is, the dose hub 14 and the pen body are preferably connected by non-self-locking threads, and in order to ensure more rotation To be smooth, the sliding friction at the threaded connection between the dose hub 14 and the pen body should be reduced as much as possible, so that lubricating oil can be added between the two.
  • the non-self-locking thread may not be used to provide other structures, so that a part of the axial thrust can be converted into a torque thrust, so as to push the dose hub 14 to rotate relative to the pen body.
  • the outer side of the dose hub 14 can be provided with an external adjustment thread 145, and the inner side of the pen body can be provided with an internal adjustment thread 151.
  • the rotation between the clutch hub 6 and the dose hub 14 is restricted by a snap-on structure that can be disengaged along the injection direction, and in the snap-on state of the snap-on structure, the dose hub 14 can provide the clutch hub 6 with a support force in the opposite direction of the injection direction. Even if the clutch hub 6 can move along the injection direction, so that the clamping structure is in the clamping state, the relative rotation between the two is restricted without breaking out of the clamping state, that is, the rotation of the dose hub 14 can drive the clutch hub 6 to rotate. , and out of the clamping state, the two can freely rotate relative to each other.
  • the end stopper 8 and the dose hub 14 are supported by the support feet 83 that can be elastically deformed along the injection direction, so that when the end stopper 8 is pushed in the injection direction to elastically deform the support feet 83, the support feet 83 can be elastically deformed.
  • simply rotating the dose hub 14 will force the clamping structure to disengage from the clamping, so that the torque cannot be transmitted, and thus the clutch hub 6 cannot be pushed to rotate synchronously.
  • the cartridge 2 When the multi-dose adjustable prefilled injection pen is used, the cartridge 2 is fixed on the pen body, and then the injection push rod 13 is abutted against the rubber stopper 3 of the cartridge 2. At this time, the dose hub 14 Relative to the pen body in the initial position. Then push the end stopper 8 along the injection direction to elastically deform the supporting feet 83, and then prevent the clamping structure from being released from the clamping. At this time, the end stopper 8 transmits the thrust in the injection direction to the dose hub 14, and the dose hub 14 will be screwed in. Because the clamping structure is clamped at this time, the dose hub 14 will drive the clutch hub 6 to rotate, so as to drive the push rod in turn.
  • the sleeve 7 is rotated and the injection plunger 13 is rotated for injection.
  • the end stopper 8 is released, and the end stopper 8 is reset.
  • the dose hub 14 can be operated and unscrewed relative to the pen body. During the unscrewing process, because there is no restriction by the end stopper 8, the dose hub 14 cannot drive the clutch hub 6 to rotate, but drives the clutch hub 6 to rotate in the injection direction.
  • an end stop 8 is provided, and through the elastic support feet 83, the rotational connection between the dose hub 14 and the clutch hub 6 is controlled, so that during injection,
  • the injection can be completed by directly pressing the end stopper, and when rotating the dose adjustment, it is only necessary to rotate the dose hub 14 alone, which makes the operation very convenient and simple, and the dose adjustment operation is simple, and the overall structure is very simple, with few parts and easy assembly. It is convenient and does not need to use structures such as metal springs, so that the overall cost is lower.
  • the multi-dose adjustable prefilled injection pen can effectively solve the problems of inconvenient operation and poor dose adjustment effect of the current injection pen.
  • a dose limit nut 5 is preferably also included here.
  • the dose limit nut 5 is connected with the clutch hub 6 through threads, and is connected with the dose hub 14 along the injection
  • the direction slip fits and limits relative rotation so that when the dose hub 14 rotates relative to the clutch hub 6, it moves in the axial direction of the clutch hub 6, that is, in the injection direction, and when the dose hub 14 relative to the clutch hub 6 rotates at a predetermined angle of rotation, The relative rotation relative to the clutch hub 6 cannot continue, so that the dose hub 14 cannot continue to rotate relative to the clutch hub 6 .
  • the dose limiting nut 5 can include a limiting inner thread 52 and a second groove 51, the second grooves 51 extending along the injection direction are respectively provided on both sides of the dose limiting nut, and the opposite sides inside the dose hub 14 are correspondingly provided There is a second protruding strip 147 to limit the relative rotation of the dose hub 14 and the dose limiting nut 5 through the second groove 51 and the second protruding strip 147 .
  • the outer side of the clutch hub 6 has a limiting outer thread 64 to match with the limiting inner thread 52.
  • the thread pitch between the dose limiting nut 5 and the clutch hub 6 can be made smaller than the distance between the dose hub 14 and the pen body.
  • the thread pitch between the two, and the former can be a self-locking thread.
  • the tip of the support foot 83 is preferably a pawl, the tip of the pawl faces the injection direction, and the support foot 83 is rod-shaped, One end has a downwardly extending and protruding pawl to serve as a support point, and the other end is connected to the body of the end stopper 8, so that the supporting foot 83 can be elastically bent, thereby changing the pawl and the end limit The relative distance of the body of the piece 8 in the injection direction.
  • the end of the dose hub 14 has support ratchet teeth 141 that cooperate with the pawls on the support foot 83 to prevent relative rotation in the precession direction of the ratchet hub 14, and then drive the end limiter 8 to synchronize during precession. Rotate and provide a supporting force to the end stop 8 in the reverse direction of the injection direction, ie in the backward direction.
  • the end limiter 8 has a limit flange 82, and the dose hub 14 is correspondingly provided with a limit groove 146 surrounded on the limit flange 82 to limit the limit flange 82 in the
  • the range of movement in the injection direction further limits the range of movement of the end limiter 8 relative to the dose hub 14 in the injection direction, and preferably the support feet 83 on the end limiter 8 are in a preloaded state.
  • the rear end of the clutch hub 6 can have a convex plate, and the front side of the convex plate has a plurality of arc-shaped protrusions 62 evenly distributed in the circumferential direction.
  • the rear end of the dose hub 14 There is an annular shoulder inside, and the rear side of the annular shoulder has arc-shaped tooth slots 142 distributed circumferentially and matched with the arc-shaped protrusion 62.
  • the arc-shaped protrusion 62 can be semi-cylindrical, and
  • the axial direction is the radial direction of the clutch hub 6,
  • the cross-section of the corresponding arc-shaped tooth slot 142 is semicircular, and the tooth tip is excessively smooth, so as to facilitate the rotation of the dose hub 14, the clutch hub 6 jumps in the injection direction to prevent
  • the clamping structure is convenient to enter and exit the clamping state, so as to avoid the transmission of torque.
  • the rear end of the clutch hub 6 and the end stopper 8 can be connected by a second group of ratchet pawl mechanisms, that is, the rear end of the clutch hub 6 has the transmission pawls 63 arranged opposite to each other, and the end There is a transmission ratchet 84 inside the stopper 8 . So that upon injection, the dose hub 14 is able to transmit torque to the end stop 8 which in turn is able to transmit torque to the clutch hub 6 . When the dose is dispensed, the transmission pawl 63 is disconnected from the transmission ratchet 84 due to the support of the foot 83 .
  • an end button 16 is preferably also included here, wherein the end button 16 is clamped around the end stopper 8 on the end stopper 8 , in order to prevent the end torque 16 from escaping from the end limiter 8.
  • the end limiter 8 has an annularly extending annular outer clip 81, and the end button is correspondingly provided with an inwardly protruding annular inner clip.
  • the middle of the end button 16 has a force transmission cylinder 161 extending along the injection direction, wherein the front end of the force transmission cylinder 161 abuts against the end stopper 8 and is spherical to reduce rotational resistance.
  • the end button 6 can be in the shape of a cap, and the inner wall of the brim has the annular inner snap protrusion 162 , the middle of the inner side has a force transmission cylinder 161 , and the end button 6 is covered on the end stopper 8 .
  • the outer side of the rear end of the cylinder is provided with an annular outer snap-on protrusion 81, and the front spherical surface of the force transmission cylinder 161 is abutted in the middle groove of the inner bottom of the rear end cylinder.
  • the pen body here includes a body barrel 15 and a push rod nut 4 that is clamped into the barrel 15.
  • the push rod nut 4 is threadedly connected to the injection push rod 13, and is
  • the push rod sleeve 7 is connected by the first group of ratchet pawl mechanisms.
  • the front end of the barrel 15 has an opening, and the inside has a limit shoulder, wherein the push rod nut 4 is loaded into the barrel 15 from the front end opening.
  • the push rod nut 4 can be provided with a threaded hole 41 that penetrates through the front and rear, and a large groove body can be provided in the rear section, and the groove wall of the large groove body can be the restricting ratchet teeth 42 of the first group of ratchet teeth and ratchet mechanisms.
  • the corresponding The front end of the push rod sleeve 7 has a first set of restricting pawls 72 of the ratchet pawl mechanism, while the outer sides of the large groove body have a third groove 43 extending along the injection direction, and the barrel 15 has a third groove 43 that is connected with the third groove 43.
  • the matching third protrusion 154 is a first set of restricting pawls 72 of the ratchet pawl mechanism, while the outer sides of the large groove body have a third groove 43 extending along the injection direction, and the barrel 15 has a third groove 43 that is connected with the third groove 43.
  • the injection push rod 13 , the push rod sleeve 7 , the clutch hub 6 , the dose limiting nut 5 , the dose hub 14 and the barrel 15 can be sleeved and arranged in sequence.
  • the rear end of the push rod sleeve 7 has a hook 74 .
  • the outer side of the dose hub 14 has a scale with a spiral distribution so that the window 152 can be passed through the window 152 in sequence during the precession, for a more accurate reading.
  • the barrel 15 has a reading mark 153, preferably in the shape of an arrow.
  • the dose hub 14 may have a zero mark 143 corresponding to the zero point of the scale, so that when the reading is zero, the zero mark 143 is aligned with the reading mark 153 .
  • the rear end of the dose hub 14 has radial splines 144 exposed on the barrel 15 to play an anti-slip effect.
  • a medicine bottle holder 10 the medicine bottle holder, the medicine bottle holder is clamped at the front end of the body tube, and the specific rear end of the medicine bottle holder 10 is inserted into the body tube.
  • 15 is open at the front end, and has a notch 101 at the rear end to locate the angular positional relationship between the barrels 15, and has an annular mounting protrusion 102 to match with the annular mounting groove 156 in the opening of the barrel 15, so as to The injection direction is positioned and clamped.
  • the rear end of the vial holder 10 has a vial ring 12, the front end of the vial ring 12 is used to abut against the vials in the vial holder 10, and the rear end against the pen body, and the front end of the injection push rod 13 has a vial ring 12.
  • the push rod knob 11 can be rotated to abut against the rubber stopper of the medicine bottle, and the front end of the medicine bottle holder 10 has a threaded post 104 for connecting the needle 1 .
  • a pen cap 9 is also provided, and the rear end of the pen cap 9 is clamped with the vial holder 10, that is, the opposite sides of the vial holder 10 have limit connection structures 103, and the corresponding rear port of the pen body has a limit connection structure along the inner side. .

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Abstract

一种多剂量可调预充注射笔，包括笔身、注射推杆（13）、推杆套筒（7）、离合器轮毂（6）、端部限位件（8）和剂量轮毂（14）。注射推杆（13）与笔身螺纹连接，推杆套筒（7）与注射推杆（13）沿注射方向滑动配合且能够传递注射推杆（13）旋进方向的扭矩，推杆套筒（7）与笔身之间通过第一组棘齿棘爪机构连接，离合器轮毂（6）与推杆套筒（7）沿注射方向滑动配合，剂量轮毂（14）与笔身通过螺纹转动连接，离合器轮毂（6）与剂量轮毂（14）之间通过能够沿注射方向脱离的卡接结构限制转动，端部限位件（8）与剂量轮毂（14）之间通过能够沿注射方向弹性变形的支撑脚部（83）支撑，在支撑脚部（83）弹性变形之前转动剂量轮毂（14）能够推动卡接结构脱离卡接，能够有效地解决目前注射笔操作不方便、剂量调节效果不好的问题。

Description

一种多剂量可调预充注射笔
本申请要求于2021年04月16日提交中国专利局、申请号为202110411143.1、发明名称为“一种多剂量可调预充注射笔”的中国专利申请，及于2021年04月16日提交中国专利局、申请号为202120784042.4、发明名称为“一种多剂量可调预充注射笔”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本发明涉及注射器材技术领域，更具体地说，涉及一种多剂量可调预充注射笔。
背景技术
目前的注射笔产品结构复杂，零部件数量多，加工工序多导致产品可靠性低；部分产品加工过程中采用胶粘的方式进行零部件之间的粘接，存在生物学风险；产品零部件涉及金属制品多，造成产品成本的上升，且使用效果不好。
综上所述，如何有效地解决目前注射笔操作不方便、剂量调节效果不好的问题，是目前本领域技术人员急需解决的问题。
发明内容
有鉴于此，本发明的目的在于提供一种多剂量可调预充注射笔，该多剂量可调预充注射笔可以有效地解决目前注射笔操作不方便、剂量调节效果不好的问题。
为了达到上述目的，本发明提供如下技术方案：
一种多剂量可调预充注射笔，包括笔身、注射推杆、推杆套筒、离合器轮毂、端部限位件和剂量轮毂，所述注射推杆与所述笔身通过轴线延伸方向为注射方向的螺纹连接，所述推杆套筒与所述注射推杆沿注射方向滑动配合且能够传递所述注射推杆旋进方向的扭矩，所述推杆套筒与所述笔 身之间通过第一组棘齿棘爪机构连接以阻止所述推杆套筒相对所述笔身绕所述注射推杆旋退方向转动，所述离合器轮毂与所述推杆套筒沿所述注射方向滑动配合且限制相对转动，所述剂量轮毂与所述笔身通过螺纹转动连接且轴向驱动所述剂量轮毂时能够推动所述剂量轮毂旋进，所述离合器轮毂与所述剂量轮毂之间通过能够沿注射方向脱离的卡接结构限制转动，所述端部限位件与所述剂量轮毂之间通过能够沿所述注射方向弹性变形的支撑脚部支撑，所述端部限位件受到所述注射方向推力以使所述支撑脚部弹性变形时，能够阻止所述卡接结构脱离卡接，且在所述支撑脚部弹性变形之前转动所述剂量轮毂能够推动所述卡接结构脱离卡接。
在该多剂量可调预充注射笔时，在使用时，将卡式瓶固定在笔身上，然后，并使注射推杆与卡式瓶的胶塞相抵，此时剂量轮毂相对笔身位于初始位置。然后沿注射方向推动端部限位件，以使支撑脚部弹性变形，然后以阻止卡接结构脱离卡接。此时端部限位件将注射方向推力传递至剂量轮毂，剂量轮毂会旋进，因为此时卡接结构卡接，所以剂量轮毂会带动离合器轮毂转动，以依次带动推杆套筒转动，注射推杆转动，以进行注射。当第一次注射完成后，松开端部限位件，端部限位件复位。此时剂量轮毂便恢复到初始位，以方便对下次注射进行剂量再次调整。当重新调整增加剂量时,可以操作剂量轮毂，相对笔身旋出，在旋出过程中，因为没有端部限位件的限制，所以剂量轮毂无法带动离合器轮毂转动，但带动离合器轮毂沿注射方向的反向滑动，而此时注射推杆以及推杆套筒相对笔身不动。而当需调整减少剂量时，则需要操作剂量轮毂旋进，因为端部限位件没有受到注射方向作用力，所以离合器轮毂亦不会转动。在该多剂量可调预充注射笔中，设置了端部限位件，通过弹性的支撑脚部，控制剂量轮毂与离合器轮毂之间的转动连接否，进而使得在注射时，直接按压端部限位件即可完成注射，而转动调节剂量时，只需要单独转动剂量轮毂即可，使得操作非常方便简单，且剂量调节操作简单，且整体结构非常简单，部件少，组装方便，且无需使用金属弹簧等结构，使得整体成本更低。综上所述，该多剂量可调预充注射笔能够有效地解决目前注射笔操作不方便、剂量调节效果不好的问题。
优选地，还包括剂量限制螺母，所述剂量限制螺母与所述离合器轮毂通过螺纹连接，且与所述剂量轮毂沿所述注射方向滑动配合且限制相对转动，以在所述剂量轮毂相对离合器轮毂转动时，沿所述离合器轮毂的轴向移动。
优选地，所述支撑脚部的尖端为棘爪，所述剂量轮毂端部具有与所述支撑脚部上棘爪相配合的棘齿，以在旋进方向阻止相对转动；所述端部限位件具有限位凸缘，所述剂量轮毂对应设置有包围在所述限位凸缘上的限位凹槽，以限制所述限位凸缘在注射方向的活动范围。
优选地，所述离合器轮毂后端具有凸盘，所述凸盘前侧具有多个周向均匀分布的弧形凸起，所述剂量轮毂后端内部具有环形肩部，所述环形肩部后侧具有周向分布且与所述弧形凸起相配合的弧形齿槽；所述离合器轮毂的后端部与所述端部限位件之间通过第二组棘齿棘爪机构连接。
优选地，还包括端部按钮，所述端部按钮周围卡设在所述端部限位件上，且中部具有沿注射方向延伸的传力圆柱，所述传力圆柱的前端与所述端部限位件相抵且呈球面型。
优选地，所述笔身包括身筒和卡入至身筒中的推杆螺母，所述推杆螺母与所述注射推杆螺纹连接，且以所述推杆套筒通过所述第一组棘齿棘爪机构连接。
优选地，所述注射推杆、所述推杆套筒、所述离合器轮毂、所述剂量限制螺母、所述剂量轮毂以及所述身筒之间依次套设设置。
优选地，所述笔身上有窗口，所述剂量轮毂外侧具有螺旋分布的刻度尺以在旋进时能够依次经过所述窗口。
优选地，还包括卡接在所述身筒前端的药瓶架，所述药瓶架后端具有药瓶环，所述药瓶环前端用于与所述药瓶架内药瓶相抵、后端与所述笔身相抵，所述注射推杆的前端具有可转动以与药瓶胶塞相抵的推杆旋钮，所述药瓶架前端具有用于连接针头的螺纹柱。
优选地，还包括笔盖，所述笔盖后端与所述药瓶架卡接。
附图说明
为了更清楚地说明本发明实施例或现有技术中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本发明的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1为本发明实施例提供的多剂量可调预充注射笔的剖面结构示意图；
图2为本发明实施例提供的多剂量可调预充注射笔的爆炸结构示意图；
图3为本发明实施例提供的多剂量可调预充注射笔去笔盖后的外部结构示意图；
图4为本发明实施例提供的多剂量可调预充注射笔剂量轮毂旋出的结构示意图；
图5为本发明实施例提供的多剂量可调预充注射笔剂量轮毂旋出的剖面结构示意图；
图6为本发明实施例提供的推杆螺帽的结构示意图；
图7为本发明实施例提供的剂量限制螺母的结构示意图；
图8为本发明实施例提供的离合器轮毂的结构示意图；
图9为本发明实施例提供的推杆套筒的结构示意图；
图10为本发明实施例提供的端部限位件的结构示意图；
图11为本发明实施例提供的药瓶架的结构示意图；
图12为本发明实施例提供的剂量轮毂的结构示意图；
图13为本发明实施例提供的身筒开口的内部结构示意图；
图14为本发明实施例提供的多剂量可调预充注射笔的后端结构示意图；
图15为本发明实施例提供的多剂量可调预充注射笔的后端爆炸结构示意图；
图16为本发明实施例提供的多剂量可调预充注射笔的后端剖面结构示意图；
图17为本发明实施例提供的离合器轮毂与剂量轮毂之间的安装示意图；
图18为本发明实施例提供的多剂量可调预充注射笔的后端安装剖面结构示意图；
图19为本发明实施例提供的剂量限制螺母与剂量轮毂之间的安装结构示意图。
附图中标记如下：
针头1、卡式瓶2、胶塞3、推杆螺母4、剂量限制螺母5、离合器轮毂6、推杆套筒7、端部限位件8、笔盖9、药瓶架10、推杆旋钮11、药瓶环12、注射推杆13、剂量轮毂14、身筒15、注射按钮16、螺纹孔41、限制棘齿42、第三凹槽43、第二凹槽51、限制内螺纹52、第一凸条61、弧形凸起62、传动棘爪63、限制外螺纹64、削平面71、限制棘爪72、第一凹槽73、卡勾74、环形外卡凸81、限位凸缘82、支撑脚部83、传动棘齿84、缺口101、安装凸起102、限位连接结构103、螺纹柱104、支撑棘齿141、弧形齿槽142、零点标识143、放射状花键144、调节外螺纹145、限位凹槽146、第二凸条147、调节内螺纹151、窗口152、读数标识153、第三凸起154、限位凸起155、环形安装凹槽156、传力圆柱161、环形内卡凸162。
具体实施方式
本发明实施例公开了一种多剂量可调预充注射笔，以有效地解决目前注射笔操作不方便、剂量调节效果不好的问题。
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没 有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
请参阅图1-图19，图1为本发明实施例提供的多剂量可调预充注射笔的剖面结构示意图；图2为本发明实施例提供的多剂量可调预充注射笔的爆炸结构示意图；图3为本发明实施例提供的多剂量可调预充注射笔去笔盖后的外部结构示意图；图4为本发明实施例提供的多剂量可调预充注射笔剂量轮毂旋出的结构示意图；图5为本发明实施例提供的多剂量可调预充注射笔剂量轮毂旋出的剖面结构示意图；图6为本发明实施例提供的推杆螺帽的结构示意图；图7为本发明实施例提供的剂量限制螺母的结构示意图；图8为本发明实施例提供的离合器轮毂的结构示意图；图9为本发明实施例提供的推杆套筒的结构示意图；图10为本发明实施例提供的药瓶架的结构示意图；图11为本发明实施例提供的药瓶架的结构示意图；图12为本发明实施例提供的剂量轮毂的结构示意图；图13为本发明实施例提供的身筒开口的内部结构示意图；图14为本发明实施例提供的多剂量可调预充注射笔的后端结构示意图；图15为本发明实施例提供的多剂量可调预充注射笔的后端爆炸结构示意图；图16为本发明实施例提供的多剂量可调预充注射笔的后端剖面结构示意图；图17为本发明实施例提供的离合器轮毂与剂量轮毂之间的安装示意图；图18为本发明实施例提供的多剂量可调预充注射笔的后端安装剖面结构示意图；图19为本发明实施例提供的剂量限制螺母与剂量轮毂之间的安装结构示意图。
在一种具体实施例中，本实施提供了一种多剂量可调预充注射笔，如附图1-3所示，该多剂量可调预充注射笔主要包括笔身、注射推杆13、推杆套筒7、离合器轮毂6、端部限位件8和剂量轮毂14，当然，还可以设置有用于放置卡式瓶2的药瓶架10、套设在笔身上的笔盖9等。
其中注射推杆13与笔身通过轴线延伸方向为注射方向的螺纹连接，以使得注射推杆13沿旋进方向转动时，注射推杆13相对笔身会有一个轴向分运动，而又因为卡式瓶2与笔身之间相对固定，一般通过药瓶架10实现相对固定，当然也可以是卡接、螺纹连接等连接方式进行相对固定。所以注射推杆13能够推动卡式瓶2内部的胶塞3沿注射方向移动，即形成注射。
其中推杆套筒7与注射推杆13沿注射方向滑动配合且能够传递注射推杆旋进方向的扭矩。具体的，如注射推杆13上设置有外螺纹，那么可以将注射推杆13一侧或相对两侧削平，推杆套筒7套设在注射推杆13外侧，且横截面对应设置，即对应设置削平面71，如呈扁平状，以限制内部注射推杆13转动，但注射推杆13能够在推杆套筒7内沿注射方向滑动，以实现滑动连接。当然也可以是在注射推杆13上设置有轴向延伸的凹槽，而推杆套筒7内侧对应设置有凸条，以通过凸条凹槽限制推杆套筒7与注射推杆13相对转动。
其中推杆套筒7与笔身之间通过第一组棘齿棘爪机构连接，以阻止推杆套筒7相对笔身绕注射推杆13旋退方向转动，且离合器轮毂6与推杆套筒7沿所述注射方向滑动配合且限制相对转动。因为推杆套筒7与注射推杆13之间限制相对转动，所以能够阻止注射推杆13向旋退方向转动，使得推杆套筒7、注射推杆13以及离合器轮毂6均仅能够绕注射推杆13旋进方向转动，此时注射推杆13进行注射。而在注射推杆13旋近时，推杆套筒7跟随转动，但注射方向上与笔身相对固定，此时注射推杆13相对推杆套筒7沿注射方向滑动。其中离合器轮毂6与推杆套筒7沿所述注射方向滑动配合且限制相对转动，具体的，可以使离合器轮毂6套设在推杆套筒7外侧，且推杆套筒7外侧面和离合器轮毂6的内侧面中，一个设置有沿注射方向延伸的凸条，另一个设置有与凸条相配合的凹槽，以限制相对转动，具体的，推杆套筒7两侧分别设置有第一凹槽73，离合器轮毂6内部相对两侧均对应设置有第一凸条61。
其中剂量轮毂14与笔身通过螺纹转动连接且轴向驱动剂量轮毂14时能够推动剂量轮毂14旋进，即剂量轮毂14与笔身之间优选通过非自锁螺纹连接，且为了保证转动更为顺畅，应尽量降低剂量轮毂14与笔身之间的螺纹连接处的滑动摩擦力，可以在两者之间增加润滑油。当然也可以不采用非自锁螺纹，以设置其它结构，以可以将轴向推力，转化一部分为扭矩推力，以推动剂量轮毂14相对笔身转动。具体的，可以使剂量轮毂14外侧具有调节外螺纹145，而笔身内侧具有调节内螺纹151。
其中离合器轮毂6与剂量轮毂14之间通过能够沿注射方向脱离的卡接 结构限制转动，且卡接结构卡接状态下，剂量轮毂14能够对离合器轮毂6提供注射方向反向的支撑力。即使得离合器轮毂6能够沿注射方向移动，以使得卡接结构进行卡接状态，在不脱离卡接状态下，两者之间限制相对转动，即剂量轮毂14的转动，能够带动离合器轮毂6转动，而脱离卡接状态，则两者可以自由相对转动。
其中端部限位件8与剂量轮毂14之间通过能够沿注射方向弹性变形的支撑脚部83支撑，以使得端部限位件8受到注射方向推力以使支撑脚部83弹性变形时，能够阻止卡接结构脱离卡接，且在支撑脚部83弹性变形之前转动剂量轮毂14能够推动卡接结构脱离卡接，即使此时卡接结构处于卡接状态，在未受到端部限位件83的限制下，单纯转动剂量轮毂14，会迫使卡接结构脱离卡接，以无法传递扭矩，进而无法推动离合器轮毂6同步转动。
在该多剂量可调预充注射笔时，在使用时，将卡式瓶2固定在笔身上，然后，并使注射推杆13与卡式瓶2的胶塞3相抵，此时剂量轮毂14相对笔身位于初始位置。然后沿注射方向推动端部限位件8，以使支撑脚部83弹性变形，然后以阻止卡接结构脱离卡接。此时端部限位件8将注射方向推力传递至剂量轮毂14，剂量轮毂14会旋进，因为此时卡接结构卡接，所以剂量轮毂14会带动离合器轮毂6转动，以依次带动推杆套筒7转动，注射推杆13转动，以进行注射。当第一次注射完成后，松开端部限位件8，端部限位件8复位。此时则需要将剂量轮毂14恢复到初始位，以方便对下次注射进行计量。则可以操作剂量轮毂14，相对笔身旋出，在旋出过程中，因为没有端部限位件8的限制，所以剂量轮毂14无法带动离合器轮毂6转动，但带动离合器轮毂6沿注射方向的反向滑动，而此时注射推杆13以及推杆套筒7相对笔身不动，直到剂量轮毂14相对笔身恢复到初始位置，即可以再次进行注射操作。而若过度转动，则需要操作剂量轮毂14旋进，因为端部限位件8没有受到注射方向作用力，所以离合器轮毂6不会转动。在该多剂量可调预充注射笔中，设置了端部限位件8，通过弹性的支撑脚部83，控制剂量轮毂14与离合器轮毂6之间的转动连接否，进而使得在注射时，直接按压端部限位件即可完成注射，而转动调节剂量时，只需要 单独转动剂量轮毂14即可，使得操作非常方便简单，且剂量调节操作简单，且整体结构非常简单，部件少，组装方便，且无需使用金属弹簧等结构，使得整体成本更低。综上所述，该多剂量可调预充注射笔能够有效地解决目前注射笔操作不方便、剂量调节效果不好的问题。
进一步，为了避免剂量锣鼓14过度转动，而超过所含剂量，此处优选还包括剂量限制螺母5，具体的该剂量限制螺母5与离合器轮毂6通过螺纹连接，且与剂量轮毂14沿所述注射方向滑动配合且限制相对转动，以在剂量轮毂14相对离合器轮毂6转动时，沿离合器轮毂6的轴向移动，即沿注射方向移动，且当剂量轮毂14相对离合器轮毂6转动角度达到预订时，无法继续相对离合器轮毂6相对转动，进而使得剂量轮毂14无法继续相对离合器轮毂6转动。具体的，可以使剂量限制螺母5包括限制内螺纹52和第二凹槽51，剂量限制螺母两侧分别设置有沿注射方向延伸的第二凹槽51，而剂量轮毂14内部相对两侧对应设置有第二凸条147，以通过第二凹槽51与第二凸条147限制剂量轮毂14与剂量限制螺母5相对转动。而对应的，离合器轮毂6的外侧具有限制外螺纹64，以与限制内螺纹52相配合，具体的，可以使剂量限制螺母5与离合器轮毂6之间的螺纹螺距小于剂量轮毂14与笔身之间的螺纹螺距，且前者可以是自锁螺纹。
进一步的，为了避免在注射时，端部限位件8相对剂量轮毂14转动，此处优选支撑脚部83的尖端为棘爪，棘爪尖端朝向注射方向，而支撑脚部83呈杆状，一端具有向下延伸且凸起的棘爪，以作为支撑点，另一端则与端部限位件8的本体连接，以使得支撑脚部83可以弹性弯曲，进而改变棘爪与端部限位件8的本体在注射方向上的相对距离。
其中剂量轮毂14端部具有与支撑脚部83上棘爪相配合的支撑棘齿141，以在棘轮轮毂14旋进方向阻止相对转动，进而在旋进时，可以带动端部限位件8同步转动，且在注射方向的反向方向，即后向方向上，对端部限位件8提供支撑力。
进一步的，为了避免端部限位件8随意晃动，尤其在注射方向上随意晃动。基于此，此处优选端部限位件8具有限位凸缘82，剂量轮毂14对应设置有包围在限位凸缘82上的限位凹槽146，以限制所述限位凸缘82 在注射方向的活动范围，进而限制端部限位件8相对剂量轮毂14在注射方向上的活动范围，且优选端部限位件8上的支撑脚部83处于预紧状态。
进一步的，为了方便设置卡接结构，具体的，可以使离合器轮毂6后端具有凸盘，凸盘前侧具有多个周向均匀分布的弧形凸起62，对应的，剂量轮毂14后端内部具有环形肩部，所述环形肩部后侧具有周向分布且与所述弧形凸起62相配合的弧形齿槽142，具体的，弧形凸起62可以呈半圆柱型，且轴线方向，为离合器轮毂6的径向方向，对应的弧形齿槽142的横截面呈半圆形，且齿尖圆滑过度，以方便转动剂量轮毂14时，离合器轮毂6在注射方向跳动，以使得卡接结构方便进出卡接状态，以避免传递扭矩。
进一步的，可以使离合器轮毂6的后端部与端部限位件8之间通过第二组棘齿棘爪机构连接，即离合器轮毂6后端具有相背设置的传动棘爪63，而端部限位件8内部具有传动棘齿84。以在注射时，剂量轮毂14能够将扭矩传递至端部限位件8，而端部限位件8能够将扭矩传递至离合器轮毂6。而在剂量调剂时，因为支撑脚部83，使得传动棘爪63与传动棘齿84脱离连接。
进一步的，为了方便在注射时，对端部限位件8施加注射方向的推力，此处优选还包括端部按钮16，其中端部按钮16周围卡设在所述端部限位件8上，以避免端部扭矩16脱离端部限位件8，具体的，端部限位件8的具有环形延伸的环形外卡凸81，而端部按钮对应设置有向内凸起的环形内卡凸162，其中环形外卡凸81前侧与环形内卡凸162的后侧相抵。且优选端部按钮16的中部具有沿注射方向延伸的传力圆柱161，其中传力圆柱161的前端与端部限位件8相抵且呈球面型，以减小转动阻力。
具体的，可以使端部按钮6呈罩帽型，且帽沿内壁具有所述环形内卡凸162，内侧中部具有传力圆柱161，且端部按钮6罩设在端部限位件8的后端筒柱上，筒柱后端外侧具有环形外卡凸81，传力圆柱161前端球面部顶在后端筒柱的内底中部槽内。
进一步的，为了方便设置笔身，此处优选笔身包括身筒15和卡入至身筒15中的推杆螺母4，所述推杆螺母4与所述注射推杆13螺纹连接，且 以所述推杆套筒7通过所述第一组棘齿棘爪机构连接，具体的，身筒15前端具有开口，内部具有限位肩，其中推杆螺母4从前端开口装入至身筒15内，直到于限位肩相抵，而且身筒15内部具有限位凸起155，以阻止推杆螺母4脱离身筒15，而在装入时，通过弹性变形，以使得可以越过该限位凸起155。具体的，可以使推杆螺母4中具有前后贯通的螺纹孔41，而后段开设大槽体，并使大槽体的槽壁为第一组棘齿棘爪机构的限制棘齿42，对应的推杆套筒7前端具有第一组棘齿棘爪机构的限制棘爪72，而大槽体两侧外部具有沿注射方向延伸的第三凹槽43，身筒15具有与第三凹槽43相配合的第三凸起154。
具体的，可以使注射推杆13、所述推杆套筒7、所述离合器轮毂6、所述剂量限制螺母5、所述剂量轮毂14以及所述身筒15之间依次套设设置。其中为了避免离合器轮毂6轴向移动过多，此处优选推杆套筒7后端具有卡勾74。
进一步的，为了方便读取剂量，此处优选身筒15上有窗口152，所述剂量轮毂14外侧具有螺旋分布的刻度尺以在旋进能够依次经过所述窗口152，为了更为精准的读数，此处优选身筒15具有读数标识153，优选呈箭型。而对应的，可以使剂量轮毂14上具有与刻度尺零点对应的零点标识143，以在读数为零时，零点标识143与读书标识153对齐时。其中为了方便转动，此处优选剂量轮毂14后端具有外露于身筒15的放射状花键144，以起到防滑的作用。
进一步的，为了方便固定卡式瓶，此处优选还包括药瓶架10，所述药瓶架，药瓶架卡接在所述身筒前端，具体的药瓶架10后端插入至身筒15前端开口中，且后端具有缺口101，以定位身筒15之间的角度位置关系，且具有环形安装凸起102，以与身筒15开口内的环形安装凹槽156相配合，以在注射方向定位卡紧。其中药瓶架10后端具有药瓶环12，药瓶环12前端用于与所述药瓶架10内药瓶相抵、后端与所述笔身相抵，所述注射推杆13的前端具有可转动以与药瓶胶塞相抵的推杆旋钮11，所述药瓶架10前端具有用于连接针头1的螺纹柱104。对应的，还设置有笔盖9，笔盖9后端与药瓶架10卡接，即药瓶架10相对两侧具有限位连接结构103，对 应的笔身后端口沿内侧具有限位连接结构。
本说明书中各个实施例采用递进的方式描述，每个实施例重点说明的都是与其他实施例的不同之处，各个实施例之间相同相似部分互相参见即可。
对所公开的实施例的上述说明，使本领域专业技术人员能够实现或使用本发明。对这些实施例的多种修改对本领域的专业技术人员来说将是显而易见的，本文中所定义的一般原理可以在不脱离本发明的精神或范围的情况下，在其它实施例中实现。因此，本发明将不会被限制于本文所示的这些实施例，而是要符合与本文所公开的原理和新颖特点相一致的最宽的范围。

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  1. 一种多剂量可调预充注射笔，其特征在于，包括笔身、注射推杆、推杆套筒、离合器轮毂、端部限位件和剂量轮毂，所述注射推杆与所述笔身通过轴线延伸方向为注射方向的螺纹连接，所述推杆套筒与所述注射推杆沿注射方向滑动配合且能够传递所述注射推杆旋进方向的扭矩，所述推杆套筒与所述笔身之间通过第一组棘齿棘爪机构连接以阻止所述推杆套筒相对所述笔身绕所述注射推杆旋退方向转动，所述离合器轮毂与所述推杆套筒沿所述注射方向滑动配合且限制相对转动，所述剂量轮毂与所述笔身通过螺纹转动连接且轴向驱动所述剂量轮毂时能够推动所述剂量轮毂旋进，所述离合器轮毂与所述剂量轮毂之间通过能够沿注射方向脱离的卡接结构限制转动，所述端部限位件与所述剂量轮毂之间通过能够沿所述注射方向弹性变形的支撑脚部支撑，所述端部限位件受到所述注射方向推力以使所述支撑脚部弹性变形时，能够阻止所述卡接结构脱离卡接，且在所述支撑脚部弹性变形之前转动所述剂量轮毂能够推动所述卡接结构脱离卡接。
  2. 根据权利要求1所述的多剂量可调预充注射笔，其特征在于，还包括剂量限制螺母，所述剂量限制螺母与所述离合器轮毂通过螺纹连接，且与所述剂量轮毂沿所述注射方向滑动配合且限制相对转动，以在所述剂量轮毂相对离合器轮毂转动时，沿所述离合器轮毂的轴向移动。
  3. 根据权利要求2所述的多剂量可调预充注射笔，其特征在于，所述支撑脚部的尖端为棘爪，所述剂量轮毂端部具有与所述支撑脚部上棘爪相配合的棘齿，以在旋进方向阻止相对转动；所述端部限位件具有限位凸缘，所述剂量轮毂对应设置有包围在所述限位凸缘上的限位凹槽，以限制所述限位凸缘在注射方向的活动范围。
  4. 根据权利要求3所述的多剂量可调预充注射笔，其特征在于，所述离合器轮毂后端具有凸盘，所述凸盘前侧具有多个周向均匀分布的弧形凸起，所述剂量轮毂后端内部具有环形肩部，所述环形肩部后侧具有周向分布且与所述弧形凸起相配合的弧形齿槽；所述离合器轮毂的后端部与所述端部限位件之间通过第二组棘齿棘爪机构连接。
  5. 根据权利要求4所述的多剂量可调预充注射笔，其特征在于，还包括端部按钮，所述端部按钮周围卡设在所述端部限位件上，且中部具有沿注射方向延伸的传力圆柱，所述传力圆柱的前端与所述端部限位件相抵且呈球面型。
  6. 根据权利要求5所述的多剂量可调预充注射笔，其特征在于，所述笔身包括身筒和卡入至身筒中的推杆螺母，所述推杆螺母与所述注射推杆螺纹连接，且以所述推杆套筒通过所述第一组棘齿棘爪机构连接。
  7. 根据权利要求6所述的多剂量可调预充注射笔，其特征在于，所述注射推杆、所述推杆套筒、所述离合器轮毂、所述剂量限制螺母、所述剂量轮毂以及所述身筒之间依次套设设置。
  8. 根据权利要求7所述的多剂量可调预充注射笔，其特征在于，所述笔身上有窗口，所述剂量轮毂外侧具有螺旋分布的刻度尺以在旋进时能够依次经过所述窗口。
  9. 根据权利要求8所述的多剂量可调预充注射笔，其特征在于，还包括卡接在所述身筒前端的药瓶架，所述药瓶架后端具有药瓶环，所述药瓶环前端用于与所述药瓶架内药瓶相抵、后端与所述笔身相抵，所述注射推杆的前端具有可转动以与药瓶胶塞相抵的推杆旋钮，所述药瓶架前端具有用于连接针头的螺纹柱。
  10. 根据权利要求9所述的多剂量可调预充注射笔，其特征在于，还包括笔盖，所述笔盖后端与所述药瓶架卡接。
PCT/CN2021/124591 2021-04-16 2021-10-19 一种多剂量可调预充注射笔 WO2022217875A1 (zh)

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