WO2022203944A1 - Procédé et appareil pour effectuer un traitement de ventilation à percussion sur une voie respiratoire d'un patient - Google Patents
Procédé et appareil pour effectuer un traitement de ventilation à percussion sur une voie respiratoire d'un patient Download PDFInfo
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- WO2022203944A1 WO2022203944A1 PCT/US2022/020855 US2022020855W WO2022203944A1 WO 2022203944 A1 WO2022203944 A1 WO 2022203944A1 US 2022020855 W US2022020855 W US 2022020855W WO 2022203944 A1 WO2022203944 A1 WO 2022203944A1
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- patient
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- interface device
- patient interface
- valve
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M16/0006—Accessories therefor, e.g. sensors, vibrators, negative pressure with means for creating vibrations in patients' airways
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M16/0009—Accessories therefor, e.g. sensors, vibrators, negative pressure with sub-atmospheric pressure, e.g. during expiration
- A61M16/0012—Accessories therefor, e.g. sensors, vibrators, negative pressure with sub-atmospheric pressure, e.g. during expiration by Venturi means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0051—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes with alarm devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
- A61M16/024—Control means therefor including calculation means, e.g. using a processor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0816—Joints or connectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0816—Joints or connectors
- A61M16/0841—Joints or connectors for sampling
- A61M16/0858—Pressure sampling ports
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
- A61M16/122—Preparation of respiratory gases or vapours by mixing different gases with dilution
- A61M16/125—Diluting primary gas with ambient air
- A61M16/127—Diluting primary gas with ambient air by Venturi effect, i.e. entrainment mixers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/20—Valves specially adapted to medical respiratory devices
Definitions
- the respiratory airways employ tiny hairs, called motile cilia, which beat in coordinated waves to facilitate removal of pulmonary mucus by directing it to the back of the throat.
- Illness such as Chronic Obstructive Pulmonary Disease (COPD) are indications of damage to the respiratory surfaces, causing inflammation (which affect the cilia’s ability to mobilize secretions), increased mucus production, and swollen passageways which restrict airflow, further reducing the body’s ability to remove mucus.
- COPD Chronic Obstructive Pulmonary Disease
- the present invention provides an effective system and method for facilitating mobilization of mucus using percussive ventilations, with reduced complexity and hence lower cost. It comprises a source of pressurized gas from a Driver unit which is supplied at constant pressure to a Patient Interface Device.
- the Patient Interface Device preferably comprises a disposable part and reusable part: the reusable part preferably employs an air interrupter valve and the disposable part preferably employs a Venturi system.
- apparatus using ADSV technology to ventilate a patient preferably has at least one Driver unit configured to provide pressurized, non-pulsate gas.
- At least one patient interface device preferably has structure configured to (i) receive the pressurized, non-pulsate gas from the driver unit and transform it into a pulsed and pressurized gas, and (ii) supply at least one sub tidal volume of pulsed and pressurized gas to a patient through a patient connection orifice.
- At least one flexible tube is preferably configured to provide pressurized, non-pulsate gas from the at least one driver unit to the at least one patient interface device.
- the at least one flexible tube has a length of from 1 -7 feet.
- Figure 6 is a schematic perspective view of a Patient Interface Device Connector for attachment to the Patient Interface Device according to the Figures 1- 3 embodiments.
- Figure 16a is a schematic cross-section view of an embodiment of the Patient Interface Device according to the present invention.
- Figure 16b is a schematic cross-section view of another embodiment of the Patient Interface Unit according to the present invention.
- the Driver Unit 10 preferably provides a source of non-pulsatile compressed air to the Patient Interface Device 16.
- the air pressure of e.g., 10 psi to the Patient Interface Device is preferably adjusted by the electronic controller 404, which powers the compressor 410.
- the electronic controller 404 preferably interface with the 4.3” graphic LCD display with integrated touchscreen 406, allowing therapeutic parameters to be configured by the caregiver(s).
- the electronic controller 404 also preferably processes signals from sensors embedded within the Patient Interface Device (to be described below) and show those feedback signals on the display 406.
- the electronic controller 404 preferably also monitors overall system health, and usage by the caregiving and/or service staff, and also preferably stores recorded session information for physicians to monitor therapeutic progress. For example, Pressures, Frequency, time, Inspiration/Expiration ratio, spirometry, alarms, etc., may be set, adjusted, controlled, stored, etc., with the controller 404.
- the Driver Unit 10 preferably includes various alarm and warning features provided by and stored in the Electronic Controller 404.
- a proximal patient High Pressure alarm is preferably preset at 60cm H20, although other and/or additional levels may be provided. If a proximal pressure is detected at the patient proximal pressure sensor (to be described below) that exceeds one or more preset pressure limit, the Electronic Controller 404 is preferably programmed to operate an alarm, e.g., at beeper 405: the alarm will sound and then percussive therapy will cease with an error message displayed on the graphic LCD display 406.
- a proximal patient Low pressure warning may also be preset at, for example, 5cm H20, although other and/or additional levels may be used.
- the exhalation Feedback signal which preferably comprises an audible beep through beeper 405, assists in training the patient to breathe comfortably through the Venturi Flow Valve within the Patient Interface Device, during the therapy session, teaching the patient to avoid exhaling too hard. Progressive and smooth exhalation permits the lung volume to decrease, making the treatment more effective and reducing the likelihood of overwhelming the patient, especially when very ill.
- the Exhalation Feedback signal is in fact, educational, teaching the patient how to breathe effectively during the therapy session, which is typically 15 to 30 minutes. Setting the Exhalation Feedback signal is performed by navigating through the Graphical User Interface (GUI) to an Exhalation Alarm Set display screen on the display 406, by using a menu touchscreen control.
- GUI Graphical User Interface
- FIG 6 is a schematic perspective view of a Patient Interface Device connector 470 for attachment to the Patient Interface Device 16 according to the Figures 1-3 embodiments.
- the quick-disconnect connector 470 preferably has a cylindrically-shaped metal or plastic housing 610 having a recessed inner deck 620 which is round and disposed below a connector lip 612 by a depth that is at least as deep as the height of an air cone 650 and/or the electrical connection pins 660i through 660n.
- the air cone 650 supplies the pressurized air to the Patient Interface Device 16, and the pins 660i through 660n provide electrical communications.
- the housing 610 preferably includes L-shaped interlocking slots 670 on two or more sides of the housing to lock the connector 470 to complementary locking structure on the Patient Interface Device 16.
- the Driver Unit 10 provides at least one continuous source of compressed air to the Patient Interface Device 16, and also provides electrical connections.
- the Patient Interface Device air hose and connector assembly preferably employs an integrated connector, where fluidic pressure lines are contained within an umbilical with spirally wound electrical wires.
- the connector 470 preferably comprises at least one centrally -mounted air-line cone connector(s), with electrical connector pins radially (and/or linearly) spaced around the cone connector(s), contained within the housing and employing a suitable ergonomic locking mechanism appropriate for the target user, such as quarter turn locking collar, lip-and-screw, etc.
- a double lumen fluidic connector may be employed.
- One or more supplemental gas(es) may be supplied to the line 822 through lines/tubes/hoses 824, through a supplemental gas port 826 disposed in a wall of the enclosure 800.
- the Venturi valve 850 may vent exhalation gas through one or more flexible hoses/tubes/lines 852 through one or more exhalation port(s) 854 in a wall of housing 800.
- the Venturi valve 850 preferably supplies one or more pulsed and pressurized gasses to the patient through one or more hoses/tubes/lines 860 through one or more delivery port(s) 862 disposed in a wall of the housing 800.
- sensors within the Venturi valve 850 supply signals to the electronic controller 404 through electrical wiring 870.
- the secondary inlet 869 is preferably capped with a one way flapper valve 871 to limit the escape of medicated aerosol, and to reduce unwanted exposure to care givers, in addition to providing a supplemental therapeutic air inlet which may be entrained by the Venturi valve 850.
- Figure 10a through 12b show embodiments of a static Venturi valve 850 integral with the disposable part 1002 of the Patient Interface Device 16, with the reusable part 1004 comprising electro-mechanical and/or pneumatic operated interrupter valves.
- Figures 13a and 13b show a Fully Disposable Patient Interface Device 16 comprising an integral, static Venturi valve 850 with an integrated, single-acting, pneumatic air interrupter 1305 employing a sliding shutle valve 1360.
- Figure 13a shows the sliding shutle valve in the closed position
- Figure 13b shows the sliding shutle valve 1360 in the open position.
- separate sources of gas 860, 1380, respectively can be utilized to supply the patient via the Venturi valve 850, and for operating the shuttle valve 1360.
- the fully disposable patient interface shutle valve 1360 preferably employs a needle valve 1370 to meter compressed gas into a sliding shutle valve.
- the shutle valve 1360 is preferably held closed by a non-linear buckling spring 1313.
- shutle valve 1360 When the pressure in the shutle valve 1360 chamber exceeds a preset threshold, the shutle overcomes the spring pressing force, and the valve 1360 moves across to open the gas passageway 1375. This opens an airway and via a drilling 1361 in the shuttle 1360, supplies gas to the Venturi valve 850.
- a second needle valve 1371 vents the chamber formed as the shutle moved across, and when exhausted, the shutle 1360 returns home due to the spring force, abruptly closing the gas supply to the Venturi valve 850.
- This needle 1371 may be replaced by a drilling if a simplified control is desired. Where extra percussion is desired, a sliding Venturi valve 850 may be employed to enhance the percussive effect by generating pressure waves as the Venturi reaches its movement limits.
- the Patient Interface Device 16 of Figures 13a and 13b may be modified, as discussed above, to provide separate gas supplies for the patient (which could be oxygen), and to activate the shuttle (which could be air), hence reducing waste of medical oxygen in hospital settings.
- a preferred embodiment may also contain heating elements within the Patient Interface Device 16 to warm the gas supplied to the patient.
- a preferred embodiment may also contain additional sensors in the Patient Interface Device 16 to monitor the administered therapy, for example, FiCh.
- the heating element(s) are implemented as one or more hot-wire(s), this permits each heating element to also function as a hot-wire anemometer to measure gas speed.
- the driver unit controller 404 also monitors the electrical power required by the heating element, and is able to calculate the air speed of passing gas as it cools the heating element.
- Figure 14a shows the sliding Venturi valve 850 in the right hand position, and the air interrupter 1475 open.
- Figure 14b shows the sliding Venturi valve 850 in the left hand position, and the air interrupter 1475 closed.
- Application of a DC electric current of one polarity to the externally mounted electromagnetic coils 1401 forces the movable Venturi valve 850 to slide in one direction, and reversing the polarity forces the movable Venturi valve 850 to slide in the other direction.
- the shuttle stroke is typically less than 1 ⁇ 4” and the shuttle mass is minimal, the shuttle is easily able to oscillate backwards and forwards at high speed, up to 15Hz.
- Monitoring electronics in the electronic controller 404 are able to detect how the current within the coil changes as the shuttle moves, and hence detect whether the shuttle is sliding, or is stuck in pace, and hence in a fault condition.
- Figures 16a and 16b show yet another Patient Interface Device 16 combining the electromagnetic sliding valve principle of Figures 14a and 14b, together with the electromagnetic interrupter of features of Figures 10a, 10b and/or Figures 11a, lib.
- Patient Interface Device 16 comprises disposable part 1602 and reusable part 1604 as described above.
- the disposable part 1602 preferably comprises an electromagnetically activated slidable Venturi valve 850
- the reusable part 1604 preferably employs an electromagnetically activated poppet valve 1622.
- Figure 16a shows a closed poppet valve 1622
- Figure 16b shows an open poppet valve 1622 - note that both shuttle valve 1660 and the slidable Venturi valve 850 may move independently.
- Figure 19a shows the sliding Venturi valve 1850 in the right hand position, and the air interrupter 11475 is open.
- Figure 19b shows the sliding Venturi valve 1850 in the left hand position, and the air interrupter 11475 closed.
- Application of a DC electric current of one polarity to the externally mounted electromagnetic coils 11401 forces the movable Venturi valve 1850 to slide in one direction, and reversing the polarity forces the movable Venturi valve 1850 to slide in the other direction.
- the shuttle stroke is typically less than 1/4” and the shuttle mass is minimal, the shuttle is easily able to oscillate backwards and forwards at high speed, up to 15Hz.
- Monitoring electronics in the electronic controller 404 are able to detect how the current within the coil changes as the shuttle moves, and hence detect whether the shuttle is sliding, or is stuck in pace, and hence in a fault condition.
- the Venturi body moves away from the resting position (open position); simultaneously gas passes through the stem passageway into the Venturi entrance and creates a flow acceleration and generates a lower than ambient pressure, due to the Venturi effect. This encourages gas (from ambient, or from a low pressure circuit) to be entrained and enter into the Venturi. Because the Venturi tube has a bigger diameter as his delivery port, the flow will decelerate, recover the pressure, and the subtidal volume is delivered to the patient airways ( Figure 20a).
- the sliding Venturi when driven to its maximal proximal position (occluded position), partially or fully obstructs the exhalation outlet port in order to reduce flow of exhalation gases. When the Venturi slider returns to the initial position (open position) after the applied pulse, the exhalation outlet port fully opens allowing gases to escape (patient exhalation).
- Figures 22a and 22b show yet another Patient Interface Device 1600 combining the electromagnetic sliding valve principle of Figures 14a and 14b, together with the electromagnetic interrupter of features of Figures 10a, 10b and/or Figures 11a, lib.
- Patient Interface Device 1600 comprises disposable part 11602 and reusable part 11604 as described above.
- the disposable part 11602 preferably comprises an electromagnetically activated sliding Venturi valve 1850
- the reusable part 11604 preferably employs an electromagnetically activated poppet valve 11622.
- Figure 22a shows a closed poppet valve 11622
- Figure 22b shows an open poppet valve 11622 - note that both shuttle valve 11660 and the sliding Venturi valve 1850 may move independently.
- FIG. 23a and 23b Yet another embodiment of a compact, fully disposable Patient Interface Device 1600 is shown in Figures 23a and 23b.
- This embodiment combines a sliding Venturi valve 1850 operated by a movable shuttle 11710.
- Fully Disposable Patient Interface Device 1600 preferably comprises a sliding Venturi valve 1850 and a movable shuttle valve 11740 as a modification of Figures 17a and 17b.
- This approach is an extension of Figures 13a and 13b, where the movable shuttle 11710 now activates the sliding Venturi valve 1850 synchronously, employing a spring return 11733.
- the buckling spring 11733 provides non-linear effect wherein a predefined chamber 11747 pressure must be reached before the spring 11733 gives, then permitting the shuttle 11710 to abruptly slide.
- Figures 24a and 24b show an additional preferred embodiment which employs a double action to forcibly return the slidable Venturi valve 1850, and does not rely on spring pressure alone.
- the double acting pneumatic slidable Venturi valve 1850 preferably employs four needle valves 11801, 11802, 11803, 11804 for maximum flexibility in configuration, and up to three gas inlets 11821, 1860, 11823.
- the first gas inlet 860 is for the patient, and may be air, O2, or a combination at an optimum therapeutic pressure.
- a simpler double acting sliding Venturi valve embodiment may have a single gas supply to both the patient and actuators, and employs a single needle valve to control frequency, with fixed drillings in place of the other needle valves to set the duty cycle, or variations there between.
- the sliding Venturi valve 1850 will be able to partially or fully occludes the expired air-port 854, increasing average positive airway pressure (PAP).
- PAP positive airway pressure
- the sliding Venturi acts as inspiratory, expiratory valves all in one.
- the expiration module 3100 has patient connection orifice 3101 that is formed at an end of the expiration module 3100, forming a gas flow path between internal space 3104 of the outer body 3102 and the patient 3004. Through the patient connection orifice 3101, inhalation gas is supplied to patient 3004 during the inspiratory phase and exhalation gas is received from the patient 3004 during the expiratory phase.
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- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Percussion Or Vibration Massage (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP22715279.0A EP4313225A1 (fr) | 2021-03-25 | 2022-03-18 | Procédé et appareil pour effectuer un traitement de ventilation à percussion sur une voie respiratoire d'un patient |
CN202280023800.8A CN117098576A (zh) | 2021-03-25 | 2022-03-18 | 为患者气道提供冲击性通气治疗的方法和设备 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17/212,571 | 2021-03-25 | ||
US17/212,571 US20210205567A1 (en) | 2016-08-02 | 2021-03-25 | Method and apparatus for providing percussive ventilation therapy to a patient airway |
Publications (1)
Publication Number | Publication Date |
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WO2022203944A1 true WO2022203944A1 (fr) | 2022-09-29 |
Family
ID=81328104
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/US2022/020855 WO2022203944A1 (fr) | 2021-03-25 | 2022-03-18 | Procédé et appareil pour effectuer un traitement de ventilation à percussion sur une voie respiratoire d'un patient |
Country Status (3)
Country | Link |
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EP (1) | EP4313225A1 (fr) |
CN (1) | CN117098576A (fr) |
WO (1) | WO2022203944A1 (fr) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4592349A (en) | 1981-08-10 | 1986-06-03 | Bird F M | Ventilator having an oscillatory inspiratory phase and method |
US7191780B2 (en) | 2003-09-22 | 2007-03-20 | Comedica Incorporated | Continuous high-frequency oscillation breathing treatment apparatus |
WO2009067554A1 (fr) * | 2007-11-19 | 2009-05-28 | Allegiance Corporation | Système de thérapie respiratoire à dispositif de commande électromécanique |
WO2018026549A1 (fr) * | 2016-08-02 | 2018-02-08 | Bougatef Adel | Appareil pour fournir une thérapie de ventilation percussive à une voie respiratoire d'un patient |
-
2022
- 2022-03-18 CN CN202280023800.8A patent/CN117098576A/zh active Pending
- 2022-03-18 WO PCT/US2022/020855 patent/WO2022203944A1/fr active Application Filing
- 2022-03-18 EP EP22715279.0A patent/EP4313225A1/fr active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4592349A (en) | 1981-08-10 | 1986-06-03 | Bird F M | Ventilator having an oscillatory inspiratory phase and method |
US7191780B2 (en) | 2003-09-22 | 2007-03-20 | Comedica Incorporated | Continuous high-frequency oscillation breathing treatment apparatus |
WO2009067554A1 (fr) * | 2007-11-19 | 2009-05-28 | Allegiance Corporation | Système de thérapie respiratoire à dispositif de commande électromécanique |
US8365727B2 (en) | 2007-11-19 | 2013-02-05 | Carefusion 2200, Inc. | Respiratory therapy system with electromechanical driver |
WO2018026549A1 (fr) * | 2016-08-02 | 2018-02-08 | Bougatef Adel | Appareil pour fournir une thérapie de ventilation percussive à une voie respiratoire d'un patient |
Also Published As
Publication number | Publication date |
---|---|
CN117098576A (zh) | 2023-11-21 |
EP4313225A1 (fr) | 2024-02-07 |
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