WO2022143499A1 - 一种局部置换膝关节软骨假体 - Google Patents
一种局部置换膝关节软骨假体 Download PDFInfo
- Publication number
- WO2022143499A1 WO2022143499A1 PCT/CN2021/141523 CN2021141523W WO2022143499A1 WO 2022143499 A1 WO2022143499 A1 WO 2022143499A1 CN 2021141523 W CN2021141523 W CN 2021141523W WO 2022143499 A1 WO2022143499 A1 WO 2022143499A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pyramid
- replacement knee
- barb
- partial replacement
- base
- Prior art date
Links
- 210000000845 cartilage Anatomy 0.000 title claims abstract description 27
- 210000000629 knee joint Anatomy 0.000 title claims abstract description 7
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 29
- 239000002184 metal Substances 0.000 claims abstract description 7
- 210000003127 knee Anatomy 0.000 claims description 16
- 210000001188 articular cartilage Anatomy 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 7
- 239000004698 Polyethylene Substances 0.000 claims description 3
- 229910002110 ceramic alloy Inorganic materials 0.000 claims description 3
- -1 polyethylene Polymers 0.000 claims description 3
- 229920000573 polyethylene Polymers 0.000 claims description 3
- 230000000694 effects Effects 0.000 description 6
- 210000001503 joint Anatomy 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000010146 3D printing Methods 0.000 description 3
- 201000009859 Osteochondrosis Diseases 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000007943 implant Substances 0.000 description 3
- 206010007710 Cartilage injury Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 201000008482 osteoarthritis Diseases 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 238000002054 transplantation Methods 0.000 description 2
- 206010023232 Joint swelling Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 230000000735 allogeneic effect Effects 0.000 description 1
- 210000001612 chondrocyte Anatomy 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 201000004595 synovitis Diseases 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/3877—Patellae or trochleae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/3886—Joints for elbows or knees for stabilising knees against anterior or lateral dislocations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
Abstract
本发明提供一种局部置换膝关节软骨假体，包括底座和关节面；其中所述底座包括棱锥和底板骨小梁，棱锥固定设置在骨小梁中间位置，且棱锥底部设置有棱锥倒刺结构。底座具有倒刺结构，可以与关节面部分的倒刺结构进行组配，倒刺结构边缘带有斜角，这样便于进行组配，使两部分倒刺结构互相勾住，产生有很强的抗拔力，可以有效防止关节面与金属部分脱位。
Description
相关申请的交叉引用
本申请要求2020年12月28日提交的中国申请号202011577242.9的权益。所述申请号202011577242.9据此全文以引用方式并入本文。
本发明涉及一种医疗器械，特别是一种局部置换膝关节软骨假体。
关节内骨软骨缺损和损伤是临床常见疾病，关节软骨损伤的代表性疾病是骨性关节炎，骨性关节炎的症状包括：最主要的症状是疼痛，初期为轻微钝痛，以后逐渐加重，活动多时加剧，休息之后有所好转。有的病人晨起时感到疼痛，稍微活动后减轻，但活动过量后疼痛就会加重，晚期会出现持续性疼痛或者是夜间痛，又叫静息痛。疼痛可与天气变化、受凉、受潮等因素有关；经常感到关节活动不灵，上下楼困难，晨起时关节固定在某个角度较长时间，出现关节僵硬，稍微活动后有所减轻；关节活动时有各种不同的响声，主要是由于关节软骨破坏，关节面不平所造成的；如果关节软骨剥脱或者掉入关节腔形成游离体，也叫关节鼠，这个时候可能会出现关节交锁；关节软骨损伤可以导致滑膜炎，形成积液，造成关节肿胀。
而目前的治疗方式有钻孔、自体活异体软骨移植以及软骨细胞移植等，但上述方式都存在修复能力有限、疾病传播、供区有限、步骤繁琐、费用昂贵等不足且并发症多的缺点。目前国内外临床极少有专用于关节内骨软骨缺损和损伤的内植物材料出现，对于大多数关节内骨软骨缺损的患者急需一种能够代替关节软骨面发挥作用的内植物。
因此，当下急需一种低摩擦系数，可长期留存体内的医用内植物代替缺损的软骨的假体。
发明内容
本发明的目的是提供一种局部置换膝关节软骨假体。
为解决上述技术问题，本发明提供一种局部置换膝关节软骨假体，包括底座和关 节面；其中所述底座包括棱锥和底板骨小梁，棱锥固定设置在骨小梁中间位置，且棱锥底部设置有棱锥倒刺结构，所述倒刺结构底部呈长方形结构、中部呈倒梯形结构、上部呈带边缘斜角的梯形结构，且上部带边缘斜角的梯形结构底边长度大于中部呈倒梯形结构的顶边长度；底座上设置有与棱锥倒刺结构适配的底座倒刺结构。
进一步的，所述底座材质为金属，所述关节面部分材料为高分子聚乙烯材料或陶瓷合金。
进一步的，所述棱锥表面设置有棱锥骨小梁结构。
进一步的，所述底板骨小梁和棱锥骨小梁结构均为网格孔隙率设置为50％～80％，孔径设置为100～400μm。
进一步的，所述关节面部分为弧形。
进一步的，所述棱锥为三棱锥，三棱锥结构高度为8-15mm。
进一步的，棱锥倒刺结构、关节面倒刺结构的上部边缘斜角均为40-45°。
使用时，将底座与关节面通过倒刺结构组合：具体的将棱锥结构通过敲击进入骨质中，棱锥的结构可以更好抗旋转，增加软骨假体的稳定性。
其中本发明相对于现有技术具有以下优点：
(1)棱锥结构表面带有一层骨小梁结构能够促进利于骨质长入，增加后期的稳定性。
(2)同时底板骨小梁结构课根据骨质去除的厚度，去选择底板骨小梁结构的厚度，从而增加假体与骨质接触面积，进一步增加假体后期的稳定性，且底板骨小梁与棱锥为一个整体，采用3D打印工艺进行实现。
(3)底座具有倒刺结构，可以与关节面部分的倒刺结构进行组配，倒刺结构边缘带有斜角，这样便于进行组配，使两部分倒刺结构互相勾住，产生有很强的抗拔力，可以有效防止关节面与金属部分脱位。
(4)关节面部分根据患者股骨、胫骨软骨生理弧度进行设计，通过患者CT数据利用软件mimics逆向原理，提取骨质表面进行设计关节面部分，精准符合患者本身软骨生理弧度，不会与正常膝关节周围关节面弧度有冲突，使其修复的软骨关节面达到顺滑效果，减少患者的痛苦；
(5)该局部置换膝关节软骨假体采用3D打印技术，因此软骨假体可以根据每一个患者缺损的大小，进行定制，从而满足每一个患者的需求，增大使用范围大。
图1是本发明局部置换膝关节软骨假体整体结构主视图；
图2是本发明局部置换膝关节软骨假体整体结构俯视图；
图3是本发明局部置换膝关节软骨假体底座主视图；
图4是本发明局部置换膝关节软骨假体关节面主视图；
1-底座，2-关节面，11-棱锥倒刺结构；12-棱锥，13-底板骨小梁；21-关节面倒刺结构。
为使本领域技术人员更好地理解本发明的技术方案，下面结合附图和具体实施方式对本发明的一种局部置换膝关节软骨假体作进一步的详细描述。
包括底座和关节面；其中所述底座包括棱锥12和底板骨小梁13，棱锥12固定设置在底板骨小梁13中间位置，且棱锥12底部设置有棱锥倒刺结构11，且棱锥倒刺结构底部穿过底板骨小梁，所述棱锥倒刺结构11底部呈长方形结构、中部呈倒梯形结构、上部呈带边缘斜角的梯形结构，且上部带边缘斜角的梯形结构底边长度大于中部呈倒梯形结构的顶边长度；关节面上设置有与棱锥倒刺结构适配的关节面倒刺结构21。其中底板骨小梁为网格孔隙率设置为50％～80％，孔径设置为100～400μm。所述棱锥为三棱锥，三棱锥结构高度为8-15mm。棱锥倒刺结构、关节面倒刺结构的上部边缘斜角均为40-45°。通过棱锥结构倒刺结构，可以与关节面倒刺结构进行组配，倒刺结构边缘带有斜角，这样便于进行组配，使两部分倒刺结构互相勾住，产生有很强的抗拔力，可以有效防止关节面与金属部分脱位。
金属底座采用具有机械强度的金属，关节面采用低摩擦系数的高分子聚乙烯或陶瓷合金制备而成。
为了利于骨质长入，在棱锥结构表面带有一层棱锥骨小梁结构，增加后期的稳定性，其中棱锥骨小梁结构的网格孔隙率设置为50％～80％，孔径设置为100～400μm。
通过患者CT数据利用软件mimics逆向原理，提取骨质表面进行设计关节面部分，将关节面部分设置为弧形。以精准符合患者本身软骨生理弧度，不会与正常膝关节周围关节面弧度有冲突，使其修复的软骨关节面达到顺滑效果，减少患者的痛苦。
其中，底板骨小梁结构课根据骨质去除的厚度，去选择底板骨小梁结构的厚度，从而增加假体与骨质接触面积，进一步增加假体后期的稳定性，且底板骨小梁与棱锥为一个整体。该局部置换膝关节软骨假体采用3D打印技术，因此软骨假体可以根据每一个患者缺损的大小，进行定制，从而满足每一个患者的需求，增大使用范围大。
使用时，将底座与关节面通过倒刺结构组合：具体的将棱锥结构通过敲击进入骨质中，棱锥的结构可以更好抗旋转，增加软骨假体的稳定性。
可以理解的是，以上实施方式仅仅是为了说明本发明的原理而采用的示例性实施方式，然而本发明并不局限于此。对于本领域内的普通技术人员而言，在不脱离本本发明的精神和实质的情况下，可以做出各种变型和改进，这些变型和改进也视为本发明的保护范围。
Claims (8)
- 一种局部置换膝关节软骨假体，其特征在于:包括底座和关节面；其中所述底座包括棱锥和底板骨小梁，棱锥固定设置在骨小梁中间位置，且棱锥底部设置有棱锥倒刺结构，底座上设置有与棱锥倒刺结构适配的底座倒刺结构。
- 根据权利要求1所述的一种局部置换膝关节软骨假体，其特征在于：所述棱锥倒刺结构贯穿底板骨小梁，所述棱锥倒刺结构底部呈长方形结构、中部呈倒梯形结构、上部呈带边缘斜角的梯形结构，且上部带边缘斜角的梯形结构底边长度大于中部呈倒梯形结构的顶边长度。
- 根据权利要求1所述的一种局部置换膝关节软骨假体，其特征在于：所述底座材质为金属，所述关节面部分材料为高分子聚乙烯材料或陶瓷合金。
- 根据权利要求1所述的一种局部置换膝关节软骨假体，其特征在于：所述棱锥表面设置有棱锥骨小梁结构。
- 根据权利要求1所述的一种局部置换膝关节软骨假体，其特征在于：所述底板骨小梁和棱锥骨小梁结构均为网格孔隙率设置为50％～80％，孔径设置为100～400μm。
- 根据权利要求1所述的一种局部置换膝关节软骨假体，其特征在于：所述关节面为弧形。
- 根据权利要求1所述的一种局部置换膝关节软骨假体，其特征在于：棱锥为三棱锥，三棱锥结构高度为8-15mm。
- 根据权利要求1所述的一种局部置换膝关节软骨假体，其特征在于：棱锥倒刺结构、关节面倒刺结构的上部边缘斜角均为40-45°。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011577242.9A CN112603606A (zh) | 2020-12-28 | 2020-12-28 | 一种局部置换膝关节软骨假体 |
| CN202011577242.9 | 2020-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2022143499A1 true WO2022143499A1 (zh) | 2022-07-07 |
Family
ID=75248208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2021/141523 WO2022143499A1 (zh) | 2020-12-28 | 2021-12-27 | 一种局部置换膝关节软骨假体 |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN112603606A (zh) |
| WO (1) | WO2022143499A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603606A (zh) * | 2020-12-28 | 2021-04-06 | 北京市春立正达医疗器械股份有限公司 | 一种局部置换膝关节软骨假体 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2307548Y (zh) * | 1997-09-17 | 1999-02-17 | 吉林市中心医院 | 碳质挠骨小头假体 |
| EP1062924A1 (fr) * | 1997-12-31 | 2000-12-27 | Merck Biomaterial France | Prothèse d'articulation de poignet |
| US20110009964A1 (en) * | 2008-02-28 | 2011-01-13 | Biopoly, Llc | Partial joint resurfacing implant, instrumentation and method |
| CN103260553A (zh) * | 2010-12-07 | 2013-08-21 | 捷迈有限公司 | 假体膝盖骨 |
| CN104434342A (zh) * | 2014-12-09 | 2015-03-25 | 张海宁 | 一种医用种植式骨软骨假体系统 |
| CN105534619A (zh) * | 2016-01-28 | 2016-05-04 | 江苏奥康尼医疗科技发展有限公司 | 一种软骨修复补偿假体 |
| CN112603606A (zh) * | 2020-12-28 | 2021-04-06 | 北京市春立正达医疗器械股份有限公司 | 一种局部置换膝关节软骨假体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2642301A1 (fr) * | 1989-01-31 | 1990-08-03 | Laboureau Jacques Philippe | Prothese composite particulierement destinee au remplacement du medaillon rotulien, des plateaux tibiaux, des cotyles ou toute autre articulation procurant un effet d'amortisseur |
| US20080243258A1 (en) * | 2005-08-24 | 2008-10-02 | Kantilal Hastimal Sancheti | Knee Joint Prosthesis |
| WO2007025290A2 (en) * | 2005-08-26 | 2007-03-01 | Isto Technologies, Inc. | Implants and methods for repair, replacement and treatment of joint disease |
| US7371260B2 (en) * | 2005-10-26 | 2008-05-13 | Biomet Sports Medicine, Inc. | Method and instrumentation for the preparation and transplantation of osteochondral allografts |
| WO2010010536A1 (en) * | 2008-07-24 | 2010-01-28 | Christiaan Rudolf Oosthuizen | Orthopedic prosthesis |
| US9622868B2 (en) * | 2014-04-28 | 2017-04-18 | Biomet Manufacturing, Llc | Convertible pre-partial knee replacement |
| CN204971711U (zh) * | 2015-05-31 | 2016-01-20 | 西安赛隆金属材料有限责任公司 | 一种高强度小孔径金属骨小梁 |
| DE102016222602A1 (de) * | 2016-11-16 | 2018-05-17 | Aesculap Ag | Implantat und Kits zum Behandeln eines Knochendefekts |
| CN208910604U (zh) * | 2018-03-03 | 2019-05-31 | 北京市富乐科技开发有限公司 | 3d打印前路融合器 |
| CN209770594U (zh) * | 2018-12-31 | 2019-12-13 | 王文军 | 自稳型多孔椎间融合器 |
-
2020
- 2020-12-28 CN CN202011577242.9A patent/CN112603606A/zh active Pending
-
2021
- 2021-12-27 WO PCT/CN2021/141523 patent/WO2022143499A1/zh active Application Filing
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2307548Y (zh) * | 1997-09-17 | 1999-02-17 | 吉林市中心医院 | 碳质挠骨小头假体 |
| EP1062924A1 (fr) * | 1997-12-31 | 2000-12-27 | Merck Biomaterial France | Prothèse d'articulation de poignet |
| US20110009964A1 (en) * | 2008-02-28 | 2011-01-13 | Biopoly, Llc | Partial joint resurfacing implant, instrumentation and method |
| CN103260553A (zh) * | 2010-12-07 | 2013-08-21 | 捷迈有限公司 | 假体膝盖骨 |
| CN104434342A (zh) * | 2014-12-09 | 2015-03-25 | 张海宁 | 一种医用种植式骨软骨假体系统 |
| CN105534619A (zh) * | 2016-01-28 | 2016-05-04 | 江苏奥康尼医疗科技发展有限公司 | 一种软骨修复补偿假体 |
| CN112603606A (zh) * | 2020-12-28 | 2021-04-06 | 北京市春立正达医疗器械股份有限公司 | 一种局部置换膝关节软骨假体 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN112603606A (zh) | 2021-04-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8591581B2 (en) | Methods of use of cartilage implants | |
| US8012217B2 (en) | Talar implants and methods of use | |
| US6102955A (en) | Surgical method, surgical tool and artificial implants for repairing knee joints | |
| WO2022143499A1 (zh) | 一种局部置换膝关节软骨假体 | |
| WO2020114252A1 (zh) | 趾关节假体及其制作方法 | |
| CN105853031B (zh) | 一种仿生防脱位人工腰椎及椎间盘连接复合体 | |
| DE102012022484B4 (de) | Prothesenliner | |
| CN103800101B (zh) | 一种防脱位式非融合人工颈椎及椎间盘系统 | |
| CN108392297A (zh) | 单髁膝关节假体 | |
| US8167952B2 (en) | Arthroplastic implant with shield for basilar joint and related methods | |
| US10285816B2 (en) | Implant including cartilage plug and porous metal | |
| CN110368140B (zh) | 股骨植入物 | |
| Ardouin et al. | A five-year prospective outcome study of Pi2 pyrocarbon arthroplasty for the treatment of thumb carpometacarpal joint osteoarthritis | |
| CN104720938A (zh) | 镍钛记忆金属人工全腕关节假体 | |
| CN211460687U (zh) | 一种人工踝关节假体组件 | |
| CN106798600B (zh) | 一种组合支架 | |
| CN204909727U (zh) | 一种胫骨置换假体 | |
| CN202409215U (zh) | 一种可调式人工颈椎及椎间连接复合体 | |
| CN214387788U (zh) | 一种膝关节骨假体 | |
| TWM273326U (en) | Prosthetic cage for spinal fusion | |
| CN214857846U (zh) | 一种寰椎侧块假体 | |
| CN209203636U (zh) | 单髁膝关节假体 | |
| Kummoona | Temporomandibular joint reconstruction with a 2-part chrome-cobalt prosthesis, chondro-osseous graft, and silastic: clinical and experimental studies | |
| CN201668542U (zh) | 钽涂层人工膝关节假体 | |
| CN216535680U (zh) | 一种趾关节假体 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 21914236 Country of ref document: EP Kind code of ref document: A1 |
|
| NENP | Non-entry into the national phase |
Ref country code: DE |
|
| 122 | Ep: pct application non-entry in european phase |
Ref document number: 21914236 Country of ref document: EP Kind code of ref document: A1 |