WO2022139758A1 - Protective face mask having antibacterial and antiviral effect with borax use - Google Patents

Protective face mask having antibacterial and antiviral effect with borax use Download PDF

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Publication number
WO2022139758A1
WO2022139758A1 PCT/TR2021/051436 TR2021051436W WO2022139758A1 WO 2022139758 A1 WO2022139758 A1 WO 2022139758A1 TR 2021051436 W TR2021051436 W TR 2021051436W WO 2022139758 A1 WO2022139758 A1 WO 2022139758A1
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Prior art keywords
face mask
protective face
mask according
borax
layer
Prior art date
Application number
PCT/TR2021/051436
Other languages
French (fr)
Inventor
Ali TAGHİZADEHGHALEHJOUGHİ
Şefika TOPDAŞ
Esra MODOĞLU
Original Assignee
Atatürk Üni̇versi̇tesi̇ Bi̇li̇msel Araştirma Projeleri̇ Bi̇ri̇mi̇
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Publication of WO2022139758A1 publication Critical patent/WO2022139758A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A41—WEARING APPAREL
    • A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/05—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
    • A41D13/11—Protective face masks, e.g. for surgical use, or for use in foul atmospheres
    • A41D13/1192—Protective face masks, e.g. for surgical use, or for use in foul atmospheres with antimicrobial agent
    • A—HUMAN NECESSITIES
    • A62—LIFE-SAVING; FIRE-FIGHTING
    • A62B—DEVICES, APPARATUS OR METHODS FOR LIFE-SAVING
    • A62B18/00—Breathing masks or helmets, e.g. affording protection against chemical agents or for use at high altitudes or incorporating a pump or compressor for reducing the inhalation effort
    • A62B18/02—Masks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/08—Filter cloth, i.e. woven, knitted or interlaced material
    • B01D39/083—Filter cloth, i.e. woven, knitted or interlaced material of organic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/1607—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous
    • B01D39/1615—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous of natural origin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/1607—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous
    • B01D39/1623—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous of synthetic origin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/04—Additives and treatments of the filtering material
    • B01D2239/0407—Additives and treatments of the filtering material comprising particulate additives, e.g. adsorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/04—Additives and treatments of the filtering material
    • B01D2239/0442—Antimicrobial, antibacterial, antifungal additives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/04—Additives and treatments of the filtering material
    • B01D2239/0464—Impregnants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/04—Additives and treatments of the filtering material
    • B01D2239/0471—Surface coating material
    • B01D2239/0478—Surface coating material on a layer of the filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/06—Filter cloth, e.g. knitted, woven non-woven; self-supported material
    • B01D2239/065—More than one layer present in the filtering material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/10—Filtering material manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/12—Special parameters characterising the filtering material
    • B01D2239/1216—Pore size

Definitions

  • the invention relates to a protective face mask developed to prevent the spread of infectious diseases infected by a breath of air contaminated by harmful viruses and/or other micro-organisms and to aid in protection against such diseases in places having viral and bacterial epidemic danger.
  • the invention particularly relates to a protective face mask with comfortable use developed for use with borax to provide effective protection against viruses and bacteria and a production method for it.
  • the mask is defined as equipment protecting people against factors of physical, chemical, and biological structures such as dust, particle, and particulates.
  • Protective masks are generally used to provide protection against dust or microorganisms. Therefore, the type of protective mask changes depending on the factor intended to be protected against. The smaller the particulate size the higher filtering function masks are preferred. To achieve its masks are produced in more than one layer and from various materials.
  • the masks used today provide protection only by porosity diameter.
  • the small diameter of the porosity of the mask makes it difficult to breathe and causes a shorter time of keeping the mask on the face. For that reason, the rate of carbon dioxide (CO2) increases and causes fast heartthrob when continued.
  • CO2 carbon dioxide
  • the masks in the market have hard structures and tight tapes, which cause reddening on the face during covering face and wounds and necrosis development thereafter. They are uncomfortable masks for long use in daily life.
  • Most masks in the market are the masks not have protection against viruses in particular but have a protective effect against particulates suspended in the air. Microporosity of masks in the market is not convenient for protection against viruses and bacteria needs development in this field.
  • Said invention relates to a functional face mask having high filtering capability, capable to measure temperature and developed to provide health and safety of people working various work areas mainly in health organisations. Virus and bacteria passing is made only by filtering system. Said mask does not have any chemical barrier to provide antiviral and antibacterial effect.
  • Another application is the application numbered TR 2020/03956 and entitled “ Hand and mouth mask”. It discloses a masking embodiment with filtering feature and fixed onto face by means of front and back elastics strip usable as hand and mouth mask. Said mask embodiment does not have a chemical barrier to provide antiviral and antibacterial effects either.
  • TR 2020/05766 relates to a medical protective face mask comprising a fabric material capable to protect people working in medical sector against infectious diseases infecting through respiratory system.
  • borax of 2% and PVac of %1 are mixed in cold soda and 280 g/m2 is used. This quantity is an excessive toxic mixture according to OECD protocol and contact to humans or animals in mask or other forms can be fatal.
  • the present invention relates to a Protective Face Mask having antibacterial and antiviral effect with Borax Use meeting the needs mentioned above, eliminating all disadvantages and providing some additional advantages, and a manufacturing method for it.
  • the primary purpose of the invention is to develop a face mask to provide protection against viral risks and also comfortable for use in daily life.
  • a protective mask having a high performance for the capability to keep virus and having an antibacterial and antiviral effect is provided by the help of chemical barrier formed by means of spraying borax of appropriate amount in salty water having high protective performance and comprising three layers to aid in the prevention of and protection against viral and bacterial infections infecting people via the respiratory system.
  • the working principle of the mask is basically based on the formation of a pool of 10-11 pH upon absorption of humidity from the mouth and trapping nano and microorganisms travelling in the air in the pool subject to turbulence and deterioration of membrane integrity thereof.
  • Another purpose of the invention is to offer a comfortable use thanks to its structure facilitating inhaling and exhaling by the help of decreasing porosity value of mask to 400- 500 nm range and keeping the mask easily without leaving tracks on the face thanks to its flexible structure. Since closing does not occur in porosities in the mask during breathing, problems caused by carbon dioxide are not experienced.
  • a further purpose of the invention is to help prevent of the spread of environmental health problems by prevention of spreading to outside from individuals having a viral infection.
  • Another purpose of the invention is to provide an economical product meeting expectations of users and providing longer comfortable use by means of its soft, flexible structure convenient for face ergonomy.
  • the invention is a protective face mask providing protection against viruses and bacteria and comprises, by weight, borax of 0,1 - 10%, polyester, acrylic or cotton of 85-95%, serum physiological or saline water of 1- 10%, acre dye, anti-bacterial dye or herbal extracts of 0,5-2%.
  • a protective face mask production method to achieve the above-mentioned purposes and comprises process steps of; i. Preparation of one inner layer, one mid-layer, and one outer layer from the mask fabric selected to produce a 3-layer mask, ii. Application of acre dye onto mid-layer, iii. Cutting fabrics forming inner layer, mid-layer, and outer layer and combining thereof to form face mask, iv. Disinfection of mask under UV rays, v. Dissolution of borax, application of solvent in a specified rate onto the outer surface of outer layer fabric of mask by spraying method.
  • the Protective Face Mask has antibacterial and antiviral effects with Borax Use having an antibacterial and antiviral effect and production method thereof a manner not forming any restrictive effect and only for purpose of better understanding of the matter.
  • the invention relates to a protective face mask with comfortable use developed for use with borax to provide effective protection against viruses and bacteria and a production method for it.
  • the protective face mask of the invention comprises borax, serum physiology, polyester, and acre dye.
  • the content of the protective mask is given in Table 1.
  • Borax was used in the content of the protective face mask of the invention to provide antibacterial and antiviral effect is an alkali agent and pH value in mask surface is 10. Serum physiology of the content has a 0,9 g/L salt rate and pH value of 7,2 and thus provides support for antiviral and antibacterial effects. Salt water or normal water can be used instead of serum physiology.
  • the polyester used as mask fabric is of porosity size of nano 400-500 nm diameter and also has an anti-allergenic effect.
  • Acre dye preferred as an antibacterial dying agent is an antibacterial paint. Another antibacterial dye or herbal extract can be used instead of acre dye.
  • Borax is used in different dosages for various purposes. Area of use varies from herbicide, pesticide to medical use area. According to OECD toxicity evaluation of borax, taking 2-5 gr of borax may cause acute toxicity and death in the end. However, according to literature publications published in low dosages, it is proved that borax of 3-8 mg doses has protective effect against oxidative stress in liver in various cases.
  • Method for production of protective face mask being subject of this invention in its basic form comprises process steps of i. preparation of one inner layer, one mid-layer, and one outer layer from the mask fabric selected to produce a 3-layer mask, ii. application of acre dye onto mid-layer, iii. cutting fabrics forming inner layer, mid-layer, and outer layer and combining thereof to form face mask, iv. disinfection of mask under UV rays, v. dissolution of borax agent, application of solvent in a specified rate onto outer surface of outer layer fabric of mask by spraying method.
  • Fabrics such as polyester, acrylic or cotton, etc. can be preferably used as fabric of protective face mask of the invention.
  • the fabric of a protective mask comprising of 3 layers namely outer, middle and inner layers close to the mouth area is not subjected to any treatment.
  • Acre dye is used in the mid-layer of the protective mask which is the second layer and as the application is made in spraying particle size (in powder) light humidity gets dried in 1 minute at room temperature.
  • After fabrics form an inner layer, the mid-layer and outer layer are cut and combined to form a face mask, they are disinfected under UV rays.
  • the borax solution is sprayed through compression onto the outer layer fabric of the mask.
  • borax is mixed and dissolved in 0,9 gr/L salt solution in a manner to be 3 mg/ml and for 30 minutes at 40-50 C degrees, it is sprayed onto the outer surface of the fabric at 10-20 bars pressure by nozzle system. As spraying is aerosol, wetting and humidity do not occur. After the spraying process, the packaging stage is started without waiting. Masks from the cabin are sterile packaged in single or multiple packages.
  • borax per mask 3 mg borax per mask is put by making it 100 times under the lowest dose in a protective face mask.
  • Borax and salt are used in the protective masks as antibacterial and antiviral effect strengthening.
  • 0.003 gr borax per mask is used in the study. Inhaling borax in the dose used in the mask does not constitute a toxic effect in health terms.
  • Masks are produced without any baking and burning, toasting in fabric structure.
  • the working principle of the mask of the invention is based on the formation of a pool of 10-11 pH upon absorption of humidity from the mouth and trapping nano and microorganisms traveling in the air in the pool subject to turbulence and deterioration of membrane integrity thereof.
  • MDBk cell line was used as cell line in method to compute antiviral activity of borax agent against Coronavirus.
  • Para-influenza virus and adenovirus which are important for the respiratory system. Detection of antiviral effect was studied by leaving borax prepared in 3 mg/ml concentration at opsonization for 1 hour with Coronavirus, para-influenza virus, and adenovirus water dilutions of various MOI rates in equal quantity (100 microliters).
  • borax virus mixtures were added to 24 cavity plate CMC-DMEM culture medium and subjected to adsorption cultivation method for 1 hour in prepared cell culture and then incubated 24 hours at 37 0C incubator. After 24 hours, the results were evaluated in terms of CPE under a reverse tissue culture microscope.
  • Coronavirus was 100% inhibited in 10, 1 , 0.1 , 0.01 MOI (infection multiplication).
  • Para-influenza virus was 100% inhibited in 10, 1 , 0.1 , 0.01 MOI (infection multiplication).
  • Adenovirus was 100% inhibited in 10, 1 , 0.1 , 0.01 MOI (infection multiplication).

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Business, Economics & Management (AREA)
  • Emergency Management (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to a protective face mask offering comfortable use and developed by use of borax having antiviral and antibacterial effects to provide effective protection against diseases infected by virus and bacteria and production method for it.

Description

Protective Face Mask Having Antibacterial and Antiviral Effect with Borax Use
The Field of the Invention
The invention relates to a protective face mask developed to prevent the spread of infectious diseases infected by a breath of air contaminated by harmful viruses and/or other micro-organisms and to aid in protection against such diseases in places having viral and bacterial epidemic danger.
The invention particularly relates to a protective face mask with comfortable use developed for use with borax to provide effective protection against viruses and bacteria and a production method for it.
Background of the Invention
In general, the mask is defined as equipment protecting people against factors of physical, chemical, and biological structures such as dust, particle, and particulates. Protective masks are generally used to provide protection against dust or microorganisms. Therefore, the type of protective mask changes depending on the factor intended to be protected against. The smaller the particulate size the higher filtering function masks are preferred. To achieve its masks are produced in more than one layer and from various materials.
The masks used today provide protection only by porosity diameter. The small diameter of the porosity of the mask makes it difficult to breathe and causes a shorter time of keeping the mask on the face. For that reason, the rate of carbon dioxide (CO2) increases and causes fast heartthrob when continued. Also, the masks in the market have hard structures and tight tapes, which cause reddening on the face during covering face and wounds and necrosis development thereafter. They are uncomfortable masks for long use in daily life. Most masks in the market are the masks not have protection against viruses in particular but have a protective effect against particulates suspended in the air. Microporosity of masks in the market is not convenient for protection against viruses and bacteria needs development in this field. When literature is searched patent application numbered TR 2020/06686 and entitled “A functional face mask” is seen, Said invention relates to a functional face mask having high filtering capability, capable to measure temperature and developed to provide health and safety of people working various work areas mainly in health organisations. Virus and bacteria passing is made only by filtering system. Said mask does not have any chemical barrier to provide antiviral and antibacterial effect.
Another application is the application numbered TR 2020/03956 and entitled “ Hand and mouth mask”. It discloses a masking embodiment with filtering feature and fixed onto face by means of front and back elastics strip usable as hand and mouth mask. Said mask embodiment does not have a chemical barrier to provide antiviral and antibacterial effects either.
Application numbered TR 2020/05766 relates to a medical protective face mask comprising a fabric material capable to protect people working in medical sector against infectious diseases infecting through respiratory system. In said invention borax of 2% and PVac of %1 are mixed in cold soda and 280 g/m2 is used. This quantity is an excessive toxic mixture according to OECD protocol and contact to humans or animals in mask or other forms can be fatal.
As a result, due to above described disadvantages and inadequacy of existing solutions it has been necessary to make development in the related art.
Brief Description of the Invention
The present invention relates to a Protective Face Mask having antibacterial and antiviral effect with Borax Use meeting the needs mentioned above, eliminating all disadvantages and providing some additional advantages, and a manufacturing method for it.
The primary purpose of the invention is to develop a face mask to provide protection against viral risks and also comfortable for use in daily life. A protective mask having a high performance for the capability to keep virus and having an antibacterial and antiviral effect is provided by the help of chemical barrier formed by means of spraying borax of appropriate amount in salty water having high protective performance and comprising three layers to aid in the prevention of and protection against viral and bacterial infections infecting people via the respiratory system. The working principle of the mask is basically based on the formation of a pool of 10-11 pH upon absorption of humidity from the mouth and trapping nano and microorganisms travelling in the air in the pool subject to turbulence and deterioration of membrane integrity thereof.
Another purpose of the invention is to offer a comfortable use thanks to its structure facilitating inhaling and exhaling by the help of decreasing porosity value of mask to 400- 500 nm range and keeping the mask easily without leaving tracks on the face thanks to its flexible structure. Since closing does not occur in porosities in the mask during breathing, problems caused by carbon dioxide are not experienced.
A further purpose of the invention is to help prevent of the spread of environmental health problems by prevention of spreading to outside from individuals having a viral infection.
Another purpose of the invention is to provide an economical product meeting expectations of users and providing longer comfortable use by means of its soft, flexible structure convenient for face ergonomy.
In order to achieve the above-mentioned purposes, the invention is a protective face mask providing protection against viruses and bacteria and comprises, by weight, borax of 0,1 - 10%, polyester, acrylic or cotton of 85-95%, serum physiological or saline water of 1- 10%, acre dye, anti-bacterial dye or herbal extracts of 0,5-2%.
A protective face mask production method to achieve the above-mentioned purposes and comprises process steps of; i. Preparation of one inner layer, one mid-layer, and one outer layer from the mask fabric selected to produce a 3-layer mask, ii. Application of acre dye onto mid-layer, iii. Cutting fabrics forming inner layer, mid-layer, and outer layer and combining thereof to form face mask, iv. Disinfection of mask under UV rays, v. Dissolution of borax, application of solvent in a specified rate onto the outer surface of outer layer fabric of mask by spraying method. The structural and characteristics features of the invention and all advantages will be understood better in detailed descriptions given below and therefore, the assessment should be made taking into account the detailed explanations.
Detailed Description of the Invention
In this detailed description, the Protective Face Mask has antibacterial and antiviral effects with Borax Use having an antibacterial and antiviral effect and production method thereof a manner not forming any restrictive effect and only for purpose of better understanding of the matter.
The invention relates to a protective face mask with comfortable use developed for use with borax to provide effective protection against viruses and bacteria and a production method for it.
In the most basic form, the protective face mask of the invention comprises borax, serum physiology, polyester, and acre dye. The content of the protective mask is given in Table 1.
Table 1 : Content of Protective face mask
Figure imgf000005_0001
Borax was used in the content of the protective face mask of the invention to provide antibacterial and antiviral effect is an alkali agent and pH value in mask surface is 10. Serum physiology of the content has a 0,9 g/L salt rate and pH value of 7,2 and thus provides support for antiviral and antibacterial effects. Salt water or normal water can be used instead of serum physiology. The polyester used as mask fabric is of porosity size of nano 400-500 nm diameter and also has an anti-allergenic effect. Acre dye preferred as an antibacterial dying agent is an antibacterial paint. Another antibacterial dye or herbal extract can be used instead of acre dye.
Borax is used in different dosages for various purposes. Area of use varies from herbicide, pesticide to medical use area. According to OECD toxicity evaluation of borax, taking 2-5 gr of borax may cause acute toxicity and death in the end. However, according to literature publications published in low dosages, it is proved that borax of 3-8 mg doses has protective effect against oxidative stress in liver in various cases.
Method for production of protective face mask being subject of this invention in its basic form comprises process steps of i. preparation of one inner layer, one mid-layer, and one outer layer from the mask fabric selected to produce a 3-layer mask, ii. application of acre dye onto mid-layer, iii. cutting fabrics forming inner layer, mid-layer, and outer layer and combining thereof to form face mask, iv. disinfection of mask under UV rays, v. dissolution of borax agent, application of solvent in a specified rate onto outer surface of outer layer fabric of mask by spraying method.
Fabrics such as polyester, acrylic or cotton, etc. can be preferably used as fabric of protective face mask of the invention. The fabric of a protective mask comprising of 3 layers namely outer, middle and inner layers close to the mouth area is not subjected to any treatment. Acre dye is used in the mid-layer of the protective mask which is the second layer and as the application is made in spraying particle size (in powder) light humidity gets dried in 1 minute at room temperature. After fabrics form an inner layer, the mid-layer and outer layer are cut and combined to form a face mask, they are disinfected under UV rays. The borax solution is sprayed through compression onto the outer layer fabric of the mask. For this stage after borax is mixed and dissolved in 0,9 gr/L salt solution in a manner to be 3 mg/ml and for 30 minutes at 40-50 C degrees, it is sprayed onto the outer surface of the fabric at 10-20 bars pressure by nozzle system. As spraying is aerosol, wetting and humidity do not occur. After the spraying process, the packaging stage is started without waiting. Masks from the cabin are sterile packaged in single or multiple packages.
3 mg borax per mask is put by making it 100 times under the lowest dose in a protective face mask. Borax and salt are used in the protective masks as antibacterial and antiviral effect strengthening. 0.003 gr borax per mask is used in the study. Inhaling borax in the dose used in the mask does not constitute a toxic effect in health terms. Masks are produced without any baking and burning, toasting in fabric structure.
The working principle of the mask of the invention is based on the formation of a pool of 10-11 pH upon absorption of humidity from the mouth and trapping nano and microorganisms traveling in the air in the pool subject to turbulence and deterioration of membrane integrity thereof.
Results on antibacterial and antiviral effect of protective face mask of the invention are proved by tests conducted at laboratories of Bursa Uludag University and Erciyes University.
Quantitative antibacterial tests are conducted on samples coded 201 and 205 if protective face mask of the invention according to Bacterial Filtration Efficiency (BFE) Test Method adapted from ASTM F2101 test method at Bursa Uludag University Medicine Faculty Medical Microbiology Laboratory and results are given in the tables below.
Table 2. information on test method
Figure imgf000008_0001
Table 3. Antibacterial efficiencies values according to Bacterial Filtration Efficiency (BFE) Test Method against Streptococcus oralisa
Figure imgf000008_0002
a. Bacteria suspension passed in concentration of 5,44x104 (log 4.74) cfu/mL for each sample of 90 mm diameter.
Samples 201 and Sample 501 bacterial filtration efficiencies were discovered for Streptococcus oralis bacteria.
In vitro antiviral activity of borax used in protective face mask of the invention was studied at Erciyes University Virology Laboratory to test in respect to corona virus, para-influenza virus and adenovirus.
MDBk cell line was used as cell line in method to compute antiviral activity of borax agent against Coronavirus. Para-influenza virus and adenovirus which are important for the respiratory system. Detection of antiviral effect was studied by leaving borax prepared in 3 mg/ml concentration at opsonization for 1 hour with Coronavirus, para-influenza virus, and adenovirus water dilutions of various MOI rates in equal quantity (100 microliters). At the end of the period, borax virus mixtures were added to 24 cavity plate CMC-DMEM culture medium and subjected to adsorption cultivation method for 1 hour in prepared cell culture and then incubated 24 hours at 37 0C incubator. After 24 hours, the results were evaluated in terms of CPE under a reverse tissue culture microscope.
Test results of 3 mg/ml borax concentration are as follows:
Coronavirus was 100% inhibited in 10, 1 , 0.1 , 0.01 MOI (infection multiplication).
Para-influenza virus was 100% inhibited in 10, 1 , 0.1 , 0.01 MOI (infection multiplication).
Adenovirus was 100% inhibited in 10, 1 , 0.1 , 0.01 MOI (infection multiplication).

Claims

1. Protective face mask providing protection against virus and bacteria and characterized in comprising borax.
2. Protective face mask according to claim 1 and characterized in comprising borax at 0,1-10% by weight.
3. Protective face mask according to claim 2 and characterized in comprising borax preferably at 3% by weight.
4. Protective face mask according to claim 1 and characterized in comprising polyester, acrylic or cotton as mask fabric.
5. Protective face mask according to claim 4 and characterized in comprising polyester, acrylic, or cotton at a rate of 85-95% by weight.
6. Protective face mask according to claim 4 and characterized in comprising polyester, acrylic or cotton preferably at rate of 86% by weight.
7. Protective face mask according to claim 1 and characterized in comprising serum physiological or salt water as solvent.
8. Protective face mask according to claim 7 and characterized in comprising serum physiological or salt water at rate of 1-10% by weight.
9. Protective face mask according to claim 7 and characterized in comprising serum physiological or salt water preferably at rate of 10% by weight.
10. Protective face mask according to claim 1 and characterized in comprising acre dye, anti-bacterial dye or herbal extracts as antibacterial dyeing agent.
11. Protective face mask according to claim 10 and characterized in comprising acre dye, anti-bacterial dye or herbal extracts at rate of 0,5-2% by weight.
12. Protective face mask according to claim 10 and characterized in comprising acre dye, anti-bacterial dye or herbal extracts preferably at rate of 1% by weight.
13. Protective face mask according to claim 1 and characterized in porosity size being in 400-500 nm range.
14. Protective face mask according to claim 1 and characterized in having three layers.
15. Production method for protective face mask and characterized in comprising the process steps of; i. preparation of one inner layer, one mid-layer and one outer layer from the mask fabric selected to produce a 3-layer mask, ii. application of acre dye onto mid-layer, iii. cutting fabrics forming inner layer, mid-layer and outer layer and combining thereof to form face mask, iv. disinfection of mask under UV rays, v. dissolution of borax agent, application of solvent in a specified rate onto outer surface of outer layer fabric of mask by spraying method.
16. Production method for protective face mask according to claim 15 and characterized in that the borax agent is mixed for preferably 30 minutes and dissolved in serum physiology at 40-50 °C in process step (ii).
17. Production method for protective face mask according to claim 15 and characterized in that borax is dissolved in 0,9 gr/L salt solution to be 3 mg/ml in process step (v).
18. Production method for protective face mask according to claim 15 and characterized in that solvent prepared in process step (v) is sprayed onto the outer surface of mask fabric at 10-20 bars pressure by “nozzle” system.
19. Production method for protective face mask according to claim 15 and characterized in that after process step (v) 3-layer mask is sterile packaged.
PCT/TR2021/051436 2020-12-22 2021-12-20 Protective face mask having antibacterial and antiviral effect with borax use WO2022139758A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2020/21348 2020-12-22
TR2020/21348A TR202021348A2 (en) 2020-12-22 2020-12-22 Borax Use Protective Face Mask with Antibacterial and Antiviral Efficacy

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5458906A (en) * 1993-09-13 1995-10-17 Liang; Paul M. S. Method of producing antibacterial fibers
WO2003094616A1 (en) * 2002-05-13 2003-11-20 Nicca Chemical Co., Ltd. Antibacterial
KR20180095492A (en) * 2018-08-20 2018-08-27 송남강 Multi-functional mask

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5458906A (en) * 1993-09-13 1995-10-17 Liang; Paul M. S. Method of producing antibacterial fibers
WO2003094616A1 (en) * 2002-05-13 2003-11-20 Nicca Chemical Co., Ltd. Antibacterial
KR20180095492A (en) * 2018-08-20 2018-08-27 송남강 Multi-functional mask

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