WO2022139726A1 - Granola contenant de la curcumine encapsulé avec des nanoparticules de polymère de chitosane - Google Patents

Granola contenant de la curcumine encapsulé avec des nanoparticules de polymère de chitosane Download PDF

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Publication number
WO2022139726A1
WO2022139726A1 PCT/TR2021/050946 TR2021050946W WO2022139726A1 WO 2022139726 A1 WO2022139726 A1 WO 2022139726A1 TR 2021050946 W TR2021050946 W TR 2021050946W WO 2022139726 A1 WO2022139726 A1 WO 2022139726A1
Authority
WO
WIPO (PCT)
Prior art keywords
curcumin
ratio
encapsulated
granola
chitosan polymer
Prior art date
Application number
PCT/TR2021/050946
Other languages
English (en)
Inventor
İhsan KARA
Aynur MÜDÜROĞLU KIRMIZIBEKMEZ
Mehmet Oktar GÜLOĞLU
Original Assignee
Ni̇şantaşi Üni̇versi̇tesi̇
İstanbul Bi̇yoteknoloji̇ Ve Laboratuar Hi̇zmetleri̇ Li̇mi̇ted Şi̇rketi̇
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ni̇şantaşi Üni̇versi̇tesi̇, İstanbul Bi̇yoteknoloji̇ Ve Laboratuar Hi̇zmetleri̇ Li̇mi̇ted Şi̇rketi̇ filed Critical Ni̇şantaşi Üni̇versi̇tesi̇
Publication of WO2022139726A1 publication Critical patent/WO2022139726A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/117—Flakes or other shapes of ready-to-eat type; Semi-finished or partly-finished products therefor
    • A23L7/126—Snacks or the like obtained by binding, shaping or compacting together cereal grains or cereal pieces, e.g. cereal bars
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons

Definitions

  • the invention relates to curcumin containing granola that is encapsulated with chitosan polymer nanoparticles, that is beneficial for human health, meets the curcumin requirement of the user in daily portion, highly nutritious and highly energetic.
  • Turmeric is a perennial herbaceous plant that is listed within the ginger family, and has yellow flowers and large leaves.
  • the main bioactive ingredient of turmeric is curcumin.
  • curcumin Along with the rich minerals and components within the content of the turmeric, curcumin has an important place in terms of health. Its benefits to the human body can be briefly listed as follows.
  • Curcumin modulates 132 signalling pathways that are found in cells within the human body. In many studies performed, its pharmacokinetics, efficacy, and safety against numerous diseases in humans have been observed. Some encouraging effects have been observed in patients with various proinflammatory diseases such as cancer, cardiovascular disease, arthritis, uveitis, ulcerative proctitis, Crohn's disease, ulcerative colitis, irritable bowel disease, tropical pancreatitis, peptic ulcer, gastric ulcer, oral lichen planus, gastroenteritis, vitiligo, psoriasis, acute coronary syndrome, atherosclerosis, diabetes, diabetic nephropathy, diabetic microangiopathy, lupus nephritis, kidney disorders, acquired immunodeficiency syndrome, [3-thalassemia, Dejerine-Sottas's disease, cholecystitis and chronic bacterial prostatitis, and idiopathic orbital inflammatory pseudotumor.
  • proinflammatory diseases such as cancer, cardiovascular
  • Curcumin has also shown protection against liver disorders, chronic arsenic exposure, and alcohol intoxication.
  • the invention relates to curcumin containing granola that ensures the daily intake of curcumin to the human body, obtained by adding to granola products and is encapsulated with chitosan polymer nanoparticles that can be protective against many diseases.
  • the invention emerges through encapsulating curcumin extract at 98% purity and putting it into granola products. All the benefits of curcumin are associated with the daily dose taken into the body. It is possible to benefit from the advantages of curcumin on health by taking the daily dose recommended in the world health researches for 3 months as to be 12 g in total. In this case, it is only possible to meet it by consuming about 130 mg daily. Curcumin is available in the content of most of the current turmeric at a rate of only 2-8%. And in this case, it ensures that the curcumin contained in most granolas remains below the daily recommended amount for the human body.
  • the granola product that is containing curcumin encapsulated with chitosan polymer nanoparticles does not cause any deterioration in the active ingredients of the materials, so, when the product is used, beneficial nutrients for the human body can be consumed in a healthy way.
  • chitosan encapsulation increases the stability and bioactivity of curcumin.
  • the present invention relates to the materials required for the preparation of granola containing curcumin encapsulated with chitosan polymer nanoparticles and their ratios by weight are as follows:
  • the process of preparing the curcumin encapsulated with chitosan polymer nanoparticles is carried out.
  • the preparation process is as follows in order; • Feeding curcumin,

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne du granola contenant de la curcumine encapsulé avec des nanoparticules de polymère de chitosane, le granola satisfaisant les besoins quotidiens en curcumine du consommateur, pouvant être facilement consommé à chaque repas avec sa teneur en flocons d'avoine, noisette, arachide, miel, eau, noix de coco séchée, abricot séché, mélasse, extrait de vanille et curcumine encapsulée.
PCT/TR2021/050946 2020-12-24 2021-09-16 Granola contenant de la curcumine encapsulé avec des nanoparticules de polymère de chitosane WO2022139726A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2020/21560A TR202021560A2 (tr) 2020-12-24 2020-12-24 Ki̇tosan poli̇meri̇ nanoparti̇külleri̇ i̇le enkapsüle edi̇lmi̇ş curcumi̇n i̇çeren granola
TR2020/21560 2020-12-24

Publications (1)

Publication Number Publication Date
WO2022139726A1 true WO2022139726A1 (fr) 2022-06-30

Family

ID=75576375

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2021/050946 WO2022139726A1 (fr) 2020-12-24 2021-09-16 Granola contenant de la curcumine encapsulé avec des nanoparticules de polymère de chitosane

Country Status (2)

Country Link
TR (1) TR202021560A2 (fr)
WO (1) WO2022139726A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008025034A2 (fr) * 2006-08-25 2008-02-28 Martek Biosciences Corporation Enrichissement des aliments à l'aide d'acides gras polyinsaturatés
WO2010124096A1 (fr) * 2009-04-24 2010-10-28 Monsanto Technology Llc Céréales, muesli et casse-croûtes sous forme de barres enrichis en oméga-3
US20140272009A1 (en) * 2013-03-14 2014-09-18 Pepsico, Inc. Chewy Granola Bar With Carbonated Candy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008025034A2 (fr) * 2006-08-25 2008-02-28 Martek Biosciences Corporation Enrichissement des aliments à l'aide d'acides gras polyinsaturatés
WO2010124096A1 (fr) * 2009-04-24 2010-10-28 Monsanto Technology Llc Céréales, muesli et casse-croûtes sous forme de barres enrichis en oméga-3
US20140272009A1 (en) * 2013-03-14 2014-09-18 Pepsico, Inc. Chewy Granola Bar With Carbonated Candy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HAMAD ALWANI, SURIYARAK SARISA, BOROMPHICHAICHARTKUL CHALEEDA: "Encapsulation of Curcumin by Spray Drying Using the Combination of Tween 80 and Chitosan", 9 June 2020 (2020-06-09), pages 96 - 109, XP055954453, [retrieved on 20220824] *

Also Published As

Publication number Publication date
TR202021560A2 (tr) 2021-01-21

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