WO2022134802A1

WO2022134802A1 - Covered stent

Info

Publication number: WO2022134802A1
Application number: PCT/CN2021/125141
Authority: WO
Inventors: 黄新鑫; 肖本好
Original assignee: 先健科技(深圳)有限公司
Priority date: 2020-12-21
Filing date: 2021-10-21
Publication date: 2022-06-30
Also published as: CN114642525A

Abstract

A covered stent (10), comprising a main body section (101), a transition section (102), and a first branch (103). The main body section (101) and the first branch (103) are connected by means of the transition section (102); the central axis of the first branch (103) is offset from the central axis of the main body section (101) and the transition section (102); and a closed surface is formed at the part of a distal end surface of the transition section (102) adjacent to the first branch (103). After the covered stent (10) is implanted into human tissue, blood flow passes through the first branch (103) of the covered stent (10) to firstly supply blood to the tissue on one side, and at an appropriate time, the closed surface on the covered stent (10) is opened to be connected to an extension stent (110), such that the blood flow passes through the extension stent (110) of the covered stent (10) to supply blood to the tissue on the other side.

Description

stent graft

technical field

The invention relates to the technical field of interventional medical devices, in particular to a covered stent.

Background technique

This section provides background information only related to the present disclosure and is not necessarily prior art.

Abdominal aortic aneurysm is one of the vascular surgical diseases, which is difficult to treat and has high surgical risk. In recent years, with the update and progress of endovascular technology and materials, more and more doctors and patients choose endovascular repair for abdominal aortic aneurysm, and the treatment results are basically satisfactory. Ruptured abdominal aortic aneurysm is a more dangerous type of abdominal aortic aneurysm with a high mortality rate. Due to the acute, critical, severe and dangerous conditions of this type of patients, the effective treatment time is short, and the preparation time is short. The treatment method is to use a straight tube stent 100' to be placed on the lesion of the abdominal aorta to isolate the blood flow from the aneurysm and prevent re-bleeding at the rupture, as shown in FIG. 1 . Since the straight tube stent 100' is used, the distal end of the stent can only be connected to the common iliac artery 210' on one side, so that the common iliac artery 220' on the other side is blocked, and there is no blood supply to the lower limb on this side. As a result, patients are prone to a series of complications after surgery.

SUMMARY OF THE INVENTION

Based on the above problems, the present invention proposes a stent graft, which is mainly achieved through the following technical solutions.

The present invention provides a stent graft, comprising a main body segment, a transition segment and a first branch, the main body segment and the first branch are connected through the transition segment, and the central axis of the first branch is offset from the main body and the central axis of the transition section, and the distal end face of the transition section forms a closed surface with the portion adjacent to the first branch.

In one embodiment, the stent-graft further includes an anchoring member disposed on the transition section and adjacent to the closing surface.

In one embodiment, the anchoring member is disposed on the inner surface of the stent-graft, and the distal end of the anchoring member is adjacent to the closing surface.

In one embodiment, the anchor is disposed outside the body segment, and the proximal end of the anchor is adjacent to the distal end of the closure surface.

In one embodiment, the anchoring member includes an open-loop wave ring, the open-loop wave ring is disposed at the proximal end of the anchor member and is connected to the stent-graft, and the circumference of the open-loop wave ring is The opening is directed towards the central axis of the main body segment.

In one embodiment, the stent-graft includes a membrane, the proximal end and the distal end of the membrane respectively form openings, and a part of the membrane at the distal end of the transition section is connected with the membrane on the opposite side to form the closed face.

In one embodiment, the stent-graft includes a second branch, and the closing surface is disposed at the proximal end of the second branch.

In one embodiment, the closed surface is sutured and closed by a suture, and the suture includes a pull wire and a suture, and the suture is constrained by the pull wire after passing through the covering film, so that the closed surface is sutured and closed. Closing; when the pulling wire is removed, the inner cavity of the transition section communicates with the inner cavity of the second branch.

In one embodiment, the distal end surface of the closed surface is inclined toward the first branch, and an included angle α exists between the distal end surface of the closed surface and a horizontal plane perpendicular to the central axis of the main body segment, The value range of the included angle α is 0°<α<90°.

In one embodiment, the stent-graft includes a membrane, the proximal end and the distal end of the membrane respectively form openings, the closing surface includes a closed structure, and the thickness of the closed structure is smaller than the thickness of the membrane Or the closed structure is integrally formed with the covering film.

After the stent-graft of the present invention is implanted into human tissue, blood flow firstly supplies blood to the tissue on one side through the first branch of the stent-graft, and at an appropriate time, the closed surface on the stent-graft is opened to form a docking port, and then The elongated stent is implanted into human tissue and docked with the docking port on the stent-graft, so that blood flow can supply blood to the tissue on the other side through the elongated stent of the stent-graft.

Description of drawings

Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are for the purpose of illustrating preferred embodiments only and are not to be considered limiting of the invention. Also, the same components are denoted by the same reference numerals throughout the drawings. In the attached image:

Fig. 1 is the structural representation of the straight tube stent used for abdominal aorta in the prior art;

FIG. 2 is a schematic structural diagram of the stent graft according to the first embodiment of the application;

FIG. 3 is a top view of an embodiment of the stent-graft shown in FIG. 2;

FIG. 4 is a top view of another embodiment of the stent-graft shown in FIG. 2;

Fig. 5 is a schematic diagram of the stent-graft shown in Fig. 2 after being implanted into the human body;

FIG. 6 is a schematic structural diagram of the stent-graft shown in FIG. 5 after the extension stent is implanted;

7 is a schematic structural diagram of a stent-graft provided with a built-in anchor according to the second embodiment of the application;

8 is a schematic structural diagram of the first embodiment of the stent-graft shown in FIG. 7 with built-in anchors (bare stent structure with interlocking wave rings);

FIG. 9 is a schematic structural diagram of a second embodiment of a built-in anchor (bare stent structure of a Z-shaped wave ring) on the stent-graft shown in FIG. 7;

Fig. 10 is a schematic diagram of the connection structure of the stent-graft shown in Fig. 7 and the built-in anchor;

11 is a schematic structural diagram of another stent-graft provided with an external anchor according to the second embodiment of the application;

Fig. 12 is a right side view of the external anchoring member (bare stent with open-loop waveform at the proximal end) on the stent-graft shown in Fig. 11;

Fig. 13 is a left side view of the external anchor (bare stent with open-loop waveform at the proximal end) on the stent-graft shown in Fig. 11;

FIG. 14 is a schematic diagram of the connection structure of the external anchor shown in FIG. 11 and the covering on the stent-graft;

FIG. 15 is a schematic diagram of the connection structure between an external anchor and the wave ring on the stent-graft shown in FIG. 11;

Figure 16 is a schematic diagram of the connection structure of another external anchor (bare stent structure with inter-hanging wave coils) shown in Figure 11 and the wave ring on the covered stent;

FIG. 17 is a schematic diagram of the connection structure of another external anchor (bare stent structure of Z-shaped wave coil) shown in FIG. 11 and the wave ring on the covered stent;

18 is a front view of the stent graft according to the third embodiment of the application;

Figure 19 is a left side view of the stent graft shown in Figure 18;

Figure 20 is a top view of the stent graft shown in Figure 18;

Figure 21 is a schematic diagram of a suture method.

Detailed ways

Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that the present disclosure will be more thoroughly understood, and will fully convey the scope of the present disclosure to those skilled in the art.

It is to be understood that the terminology used herein is for the purpose of describing particular example embodiments only and is not intended to be limiting. As used herein, the singular forms "a," "an," and "the" can also be intended to include the plural forms unless the context clearly dictates otherwise. The terms "comprising", "comprising", "containing" and "having" are inclusive and thus indicate the presence of stated features, steps, operations, elements and/or components, but do not preclude the presence or addition of one or Various other features, steps, operations, elements, components, and/or combinations thereof. Method steps, procedures, and operations described herein are not to be construed as requiring that they be performed in the particular order described or illustrated, unless an order of performance is explicitly indicated. It should also be understood that additional or alternative steps may be used.

Although the terms first, second, etc. may be used herein to describe various elements, components, regions, layers and/or sections, these elements, components, regions, layers and/or sections should not be described by these terms limit. These terms may only be used to distinguish one element, component, region, layer or section from another region, layer or section. Terms such as "first," "second," "third," and other numerical terms when used herein do not imply a sequence or order unless clearly indicated by the context. Thus, a first element, component, region, layer or section discussed below could be termed a second element, component, region, layer or section without departing from the teachings of example embodiments.

For ease of description, spatially relative terms such as "inside", "surface", "inside" may be used herein to describe the relationship of one element or feature to another element or feature as shown in the figures ", "outside", "below", "below", "above", "above", etc. This spatially relative term is intended to include different orientations of the device in use or operation other than the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" or "above the other elements or features" above features". Thus, the example term "below" can encompass both an orientation of above and below. The device may be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptions used herein interpreted accordingly.

In the field of medical devices, the direction of blood inflow is defined as the "proximal end", and the direction of blood flow out is defined as the "distal end". When the stent is implanted in a blood vessel, blood flows from the proximal end of the stent into the lumen of the stent and out of the distal end of the stent.

The specific structure and technical effect of the stent graft 10 proposed in the present application will be described in detail below through specific embodiments.

Example 1

As shown in FIG. 2 , the stent-graft 10 of the present embodiment generally has a tubular structure with openings at both ends. The stent graft 10 includes a plurality of wave coils 1012 and a membrane 1011 . The plurality of wave coils 1012 are arranged along the length direction of the stent graft 10, and the plurality of wave coils 1012 are arranged on the inner surface and/or the outer surface of the stent graft 1011 by means of sewing or heat treatment. The coating 1011 can be made of a material with good biocompatibility such as PET or PTFE, and the wave ring 1012 is also made of a material with good biocompatibility, such as nickel-titanium and other materials.

In order to improve the anchoring ability of the stent-graft 10 on human tissue, a bare stent 1013 may also be provided at the proximal end of the stent-graft 10, and the bare stent 1013 may not be provided with a coating. And the bare stent 1013 can be further provided with anchors 1014, the stent-graft 10 is anchored to the human tissue through the bare stent 1013 and the anchors 1014 provided on the bare stent 1013, so as to improve the adhesion of the stent-graft 10 on the human tissue. Anchor stability.

Referring to FIG. 2 , the stent graft 10 of this embodiment includes a main body section 101 , a transition section 102 and a first branch 103 . The distal end of the main body section 101 and the proximal end of the first branch 103 are connected by a transition section 102, and in a natural state, the central axis of the first branch 103 deviates from the central axis of the main body section 101 and the transition section 102, and the transition section The portion of the distal face of 102 adjacent to the first branch forms a closed face 104 .

Specifically, the distance between the central axis of the first branch 103 and the central axis of the main body segment 101 is L, preferably, 0<L<D/2 (D is the diameter of the main body segment 101 ). Preferably, the diameter of the main body section 101 is greater than twice the diameter of the first branch 103, that is, there is a gap between the tube wall of the first branch 103 and the central axis of the main body section 101, so that the closing surface 104 of the transition section has a gap. Sufficient implantation space is reserved for the later implantation of the extension stent, which is beneficial to reduce the operation difficulty of the implantation operation, reduce the time of the implantation operation, and reduce the probability of complications for the patient due to the long operation time.

As shown in FIG. 1 , the closing surface 104 includes an inclined surface inclined toward the first branch, and the included angle between the distal end surface of the closing surface 104 and the horizontal direction is α. In order to prevent the blood flowing into the stent-graft 10 from accumulating at the closing surface 104 to form a thrombus after the stent-graft 10 is implanted into the tissue and before the extension stent is implanted, the value range of α can be 0°<α<90°, 30° is preferred. Therefore, the closed surface 104 forms an inclined surface inclined toward the first branch 103 , and the blood flowing into the stent graft 10 can flow into the first branch 103 at the inclined surface of the closed surface 104 , thereby reducing blood accumulation at the closed surface 104 to form a thrombus. The phenomenon. At the same time, it can be avoided that the oblique angle of the closing surface 104 is too large, which increases the difficulty of the subsequent opening and implantation operation, and reduces the probability of complications for the patient due to the long operation time.

Referring to FIGS. 3 and 4 , the closing surface 104 is provided with a closing structure 109 . The closing structure in this embodiment is made of a film. The closing structure 109 of the closing surface 104 can be the same as the covering film 1011 of the stent graft 10 . One-piece molding (as shown in Figure 3). The closure structure 109 may also be fixed on the closure surface 104 by subsequent stitching or heat treatment (as shown in FIG. 4 ). At this time, the area of the closure structure 109 may be equal to or smaller than the closure surface 104 . Preferably, the closure structure 109 is thinner and easier to open than the membrane 1011 on the stent graft 10, so as to avoid failure to open or the opening is too small due to the overly thick membrane at the closing surface 104, which affects the connection between the stent graft 10 and the extension stent. Therapeutic effects of docking and stent-graft 10.

The effect of the stent graft 10 of the present embodiment after implantation is shown in FIGS. 5 and 6 . When treating a patient with ruptured abdominal aortic aneurysm, after the stent graft 10 of the present embodiment is implanted in the patient’s body, the inflow The blood in the stent graft 10 first supplies blood to the iliac artery on one side through the first branch 103, so as to obtain a certain survival time for the patient. After the patient is stabilized at a later stage, the closed surface 104 on the stent-graft 10 is opened again, so that the stent-graft 10 is formed with a docking port that can be docked with the extension stent 110, and the extension stent 110 is inserted at the docking port to restore the opposite side. The blood supply of the iliac artery can avoid a series of complications caused by the ischemia of the lower extremity caused by the long-term closure of one iliac artery.

It should be noted that the above embodiments illustrate the stent graft 10 through the iliac artery, but do not limit the type and application range of the stent graft 10. For example, in other embodiments of the present application, the stent graft can also be The stent 10 is used for other tissues in the human body, and will not be described one by one here. In addition, the above-mentioned embodiment describes the implantation of one extended stent on the stent-graft 10, but does not limit the number of extended stents implanted on the stent-graft 10. For example, in other embodiments of the present application, there are also Two or more extended stents may be provided on the stent-graft 10, and such adjustment also falls within the scope of the concept of the present application.

Embodiment 2

Referring to FIG. 7 , the stent-graft 10 of this embodiment is basically the same in structure as the stent-graft of Embodiment 1, except that the stent-graft 10 of this embodiment further includes an anchoring member 105 disposed on the transition section , and the anchor 105 is adjacent to the closing surface 104 . The anchor 105 includes a bare stent structure composed of wave circles. When the extension stent 110 is implanted later, the extension stent is connected to the stent-graft 10 through the anchor 105. The anchor 105 can enhance the connection between the extension stent and the stent-graft 10. The connection stability between the two can be avoided, and the displacement of the extension stent on the stent-graft 10 is avoided.

Referring to FIGS. 7 and 8 , the anchoring member 105 is disposed on the inner surface of the stent-graft 10 , specifically in the transition section 102 , and is close to the proximal end of the closing surface 104 , that is, the distance between the closing surface 104 and the anchoring member 105 The ends are adjacent and preferably the distal end of the anchor 105 is flush with the end face of the closure face 104 . Further, since the included angle between the closing surface 104 and the horizontal direction of the main body section 101 on the stent-graft 10 is α, the included angle β between the distal end of the anchor 105 disposed on the closing surface 104 and the horizontal direction should be equal to the closing angle β. The included angle α between the surface 104 and the horizontal direction ensures that the contact surface between the anchoring member 105 and the closing surface 104 is completely consistent, and avoids that due to the incompatibility between the contacting surface of the anchoring member 105 and the closing surface 104, the film is assembled and released during assembly and release. During the process of the stent 10, the closing surface 104 is damaged, resulting in the phenomenon that the closing surface 104 is opened in advance.

8, the height L ₀ of the anchor 105 is preferably 10mm≤L ₀ ≤ the sum of the heights of the main body section 101 and the transition section 102, so as to avoid the insufficient height of the anchor 105, causing the extension bracket 110 to be inserted After closing the surface 104 and the anchoring member 105, due to insufficient connecting force, the extension stent 110 is displaced or endoleaked, or because the height of the anchoring member 105 is too high, the compression diameter of the stent-graft 10 during assembly increases, The difficulty of assembling and releasing the stent graft 10 is increased.

Referring to FIGS. 8 and 9 , the bare stent structure on the anchoring member 105 may be an inter-hanging wave ring structure, or a Z-shaped wave ring structure formed separately, and then connected by connecting members. The built-in anchors 105 in this embodiment are preferably inter-hanging wavy coil structures. Since the inter-hanging wavy coil structures can be braided with nickel-titanium materials with smaller wire diameters, no additional fixing is required, thereby reducing the size of the anchoring parts 105 . Influence on the compressed diameter of the stent-graft 10 during assembly.

Referring to FIG. 10 , the connection between the anchoring member 105 and the inner surface of the stent-graft 10 may be suture, heat treatment, or adhesion. The lateral axial position of the anchoring member 105 needs to be connected with the stent-graft 10, and the axial position of the anchoring member 105 is guaranteed not to move or shorten through the connection point 106. At least a part of the circumferential direction of the distal end surface of the anchoring member 105 needs to be connected with the closing surface 104 to ensure that the anchoring member 105 will not move in the radial direction after being installed.

In addition, as shown in FIG. 11 , in other embodiments, the anchoring member 105' may also be disposed on the outer side of the stent-graft 10, and the proximal end of the anchoring member 105' is connected to the distal end of the closing surface 104. That is, the proximal end of the anchoring member 105' is adjacent to the closing surface 104, so that the interference of the anchoring member 105' to the blood flow in the lumen of the main body segment 101 can be avoided, and the patency of the blood flow in the lumen of the stent graft 10 can be ensured.

An embodiment of the external anchoring member 105' is shown in Figures 12 and 13. The anchoring member 105' includes a proximal open-loop wave ring 1051' and a main body wave ring 1052'. The proximal open-loop wave ring 1051' is used to connect with the stent-graft 10, and the circumferential opening of the open-loop wave ring 1051 faces the central axis of the main body segment. The height L1 of the proximal open-loop wave ring 1051' is preferably 0<L1≤15mm, so as to ensure a stable connection between the anchoring member 105' and the stent graft 10. Preferably, the circumferential length of the open-loop wave ring is less than half of the circumferential length of the other main wave rings, so as to minimize the influence of the open-loop wave ring on blood flow.

The connection between the proximal open-loop wave ring 1051' on the anchoring member 105' and the stent-graft 10 can be referred to as shown in Figs. Partially overlapping, preferably the proximal open-loop wave ring 1051' is connected to the outer surface of the graft through the suture 106, so as to avoid the overlap with the wave ring on the stent graft 10 as much as possible, and reduce the compression diameter of the stent caused by the overlapping of the wave ring. This increases the phenomenon, thereby increasing the difficulty of assembling and releasing the stent graft 10 . It can be understood that the open-loop wave ring 1051' at the proximal end of the anchoring member 105' can also be connected and fixed with the wave ring 107 on the stent-graft 10 through the suture 106.

12 and 13, the height L0 of the main wave ring 1052' on the anchoring member 105' is preferably 0<L0≤60mm. In this embodiment, the height of L0 is preferably set to 30 mm, which can ensure that after the closing surface 104 on the stent-graft 10 is opened, the anchoring length of the stent 110 and the anchoring member 105 ′ is extended, so as to ensure the extension of the stent 110 and the stent-graft 10 . connection stability. If L0 is too small, the connection stability between the extension stent and the stent-graft will be weakened.

As shown in FIG. 16 and FIG. 17 , in other embodiments, the anchoring member 105 ″ can also be connected to the corrugated coil stent 117 on the stent-graft through a separate connecting member. The connecting member includes a stainless steel sleeve 116 ′ and a connecting rod 108 The number of connecting rods 108 is at least one. In this embodiment, the number of connecting rods 108 is preferably three, so as to ensure the stability of the connection between the anchor 105 ″ and the corrugated stent 117 on the stent graft 10 . The anchor 105 ″ in this embodiment can avoid subsequent connection with other components on the stent graft 10 , thereby reducing the risk of damage to other components on the stent graft 10 . And the anchor 105 ″ in this embodiment does not need to be connected with the stent graft 10 . The stent-graft 10 is covered with a film for suture, so that no suture holes are generated, and the risk of endoleak caused by the large-covered pores of the stent-graft 10 is reduced.

It can be understood that, in other embodiments, the anchoring member can also be an open structure, such as a curved one-sided structure.

Embodiment 3

18 and 19, the stent graft 10' of this embodiment is basically the same in structure as the stent graft 10 of the first embodiment, and the difference lies in the closing surface 104'. The closed surface 104' of this embodiment does not have a closed structure, but directly connects a part of the film at the distal end of the transition section 102' with the opposite side film by means of sewing or heat treatment, thereby forming the closed surface 104'.

The stent graft in this embodiment further includes a second branch 111 ′. After the closing surface 104 ′ is opened, the extension stent is directly matched and connected with the second branch 111 ′ on the stent graft 10 ′. The film-covered structure, so after connecting with the extension stent, the film-covered structure on the second branch 111' will increase the mating contact area with the extension stent, increase the friction force between the second branch 111' and the extension stent, and improve the covered stent. The connection strength between the stent graft 10' and the extension stent ensures the stability of the connection between the covered stent 10' and the extension stent. In addition, since a layer of film is added to the mating area between the second branch 111' on the stent-graft 10' and the extension stent, the probability of endoleak at the connecting portion is also reduced. Moreover, after the extension stent is implanted, it is directly connected to the second branch, without extending into the transition section, and will not affect the blood flow before flowing into the branch.

Referring to FIG. 18 , the closing surface 104 ′ of this embodiment is disposed at the proximal end of the second branch 111 ′, and the included angle α between the distal end surface of the closing surface 104 ′ and the horizontal direction of the stent graft 10 ′ satisfies 0°< α<90°, which can prevent the blood flowing into the stent graft 10' from accumulating at the closing surface 104' to form a thrombus after the stent graft 10' is implanted and before the closing surface 104' is opened, and the thrombus will follow the blood flow. The flow flows in the direction of the lower extremity, blocks the arteries of the lower extremity, and affects the therapeutic effect after the closure surface 104' is opened.

Referring to FIG. 20 , the closing surface 104 ′ of this embodiment can be directly sutured and closed at the proximal end of the second branch 111 ′ on the stent-graft 10 ′ with suture, or the second branch 111 ′ on the stent graft 10 ′ can be directly sutured and closed by means of heat treatment, bonding, etc. The proximal end of the branch 111' is pre-occluded. In this embodiment, the sealing method is preferably performed by suturing, and the method shown in FIG. 21 can be used for suturing. Specifically, the pulling thread 1041' and the suture 1042' are used for suturing. The suture 1042' goes in and out from the same through hole twice, and bypasses the suture 1042' when going in and out, so that the suture 1042' will not pass through the through hole. Pull out so that the two sides of the film are joined together. After the pulling wire 1041 ′ is removed, the suture 1042 ′ is no longer restricted and can be easily pulled out from the through hole, so that the two sides of the film are also separated accordingly, so that the inner cavity of the transition section communicates with the inner cavity of the second branch . In this embodiment, the pulling wire 1041 ′ can be arranged on the outer side of the stent graft 10 ′ and higher than the proximal end or the distal end of the main body segment 101 ′. After the stent graft 10 ′ is implanted, during the implantation operation, only the Using a catcher to pull the pull wire 1041' out of the body, the closing surface 104' on the stent graft 10' can be opened. This embodiment can effectively reduce the influence of the arrangement of the closing surface 104' on the compression diameter of the stent graft 10', and avoid increasing the difficulty of assembling and releasing the stent graft 10' due to the arrangement of the closing surface 104'.

In addition, the purpose of opening and closing the closing surface 104' is achieved through the cooperation of the pulling wire 1041' and the suture 1042', which can improve the opening and closing efficiency of the closing surface 104', and avoid opening failure or too small opening due to the difficulty of opening and closing the closing surface 104'. , affecting the docking of the stent-graft 10 and the extension stent and the therapeutic effect of the stent-graft 10 .

It should be noted that, in the drawings implemented in the present application, setting the second branch 111 ′ as a straight pipe is only an example of the embodiment of the present application, and does not limit the shape of the second branch 111 ′, for example, according to In other embodiments of the present application, the shape of the second branch 111 ′ can also be provided with a curved pipe, or in other words, the shape of the second branch 111 ′ matches the shape of the extension bracket, and these structural adjustments belong to the embodiments of the present application protection range of the second branch 111 ′.

The above description is only a preferred embodiment of the present invention, but the protection scope of the present invention is not limited to this. Substitutions should be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

A stent graft, comprising a main body segment, a transition segment and a first branch, wherein the main body segment and the first branch are connected through the transition segment, wherein the central axis of the first branch is offset from the main body and the central axis of the transition section, and the distal end face of the transition section forms a closed surface with the portion adjacent to the first branch.
The stent-graft according to claim 1, wherein the stent-graft further comprises an anchoring member, and the anchoring member is disposed on the transition section and is adjacent to the closing surface.
The stent-graft according to claim 2, wherein the anchoring member is disposed on the inner surface of the stent-graft, and the distal end of the anchoring member is adjacent to the closing surface.
The stent graft according to claim 2, wherein the anchoring member is disposed on the outer side of the main body segment, and the proximal end of the anchoring member is adjacent to the distal end of the closing surface.
The stent graft according to claim 4, wherein the anchoring member comprises an open-loop wave ring, and the open-loop wave ring is disposed at the proximal end of the anchoring member and is connected to the stent-graft , the circumferential opening of the open-loop wave ring faces the central axis of the main body section.
The stent-graft according to claim 1, wherein the stent-graft comprises a membrane, the proximal end and the distal end of the membrane respectively form openings, and a portion of the distal end of the transition section is covered with a membrane The closed surface is formed by connecting with the opposite side covering film.
The stent graft according to claim 6, wherein the stent graft comprises a second branch, and the closing surface is disposed at the proximal end of the second branch.
The stent graft according to claim 7, wherein the closed surface is sutured and closed by a suture, and the suture comprises a pull wire and a suture, and the suture is passed through the covering and is sutured by the suture. The pulling wire is constrained so that the closing surface is closed; after the pulling wire is removed, the inner cavity of the transition section communicates with the inner cavity of the second branch.
The stent graft according to any one of claims 1 to 8, wherein the distal end surface of the closing surface is inclined toward the first branch, and the distal end surface of the closing surface is perpendicular to the There is an included angle α between the horizontal planes of the central axis of the main body section, and the value range of the included angle α is 0°<α<90°.
The stent-graft according to claim 9, wherein the stent-graft comprises a membrane, the proximal end and the distal end of the membrane respectively form openings, the closing surface comprises a closed structure, and the closed structure The thickness of the film is smaller than the thickness of the cover film or the closed structure is integrally formed with the cover film.