WO2022090807A3 - Cannabigerol and tetrahydrocannabivarin antidote formulations and methods of using the same - Google Patents
Cannabigerol and tetrahydrocannabivarin antidote formulations and methods of using the same Download PDFInfo
- Publication number
- WO2022090807A3 WO2022090807A3 PCT/IB2021/000776 IB2021000776W WO2022090807A3 WO 2022090807 A3 WO2022090807 A3 WO 2022090807A3 IB 2021000776 W IB2021000776 W IB 2021000776W WO 2022090807 A3 WO2022090807 A3 WO 2022090807A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tetrahydrocannabivarin
- cannabigerol
- methods
- same
- antidote
- Prior art date
Links
- ZROLHBHDLIHEMS-HUUCEWRRSA-N (6ar,10ar)-6,6,9-trimethyl-3-propyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCC)=CC(O)=C3[C@@H]21 ZROLHBHDLIHEMS-HUUCEWRRSA-N 0.000 title abstract 3
- ZROLHBHDLIHEMS-UHFFFAOYSA-N Delta9 tetrahydrocannabivarin Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCC)=CC(O)=C3C21 ZROLHBHDLIHEMS-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000729 antidote Substances 0.000 title abstract 2
- QXACEHWTBCFNSA-SFQUDFHCSA-N cannabigerol Chemical compound CCCCCC1=CC(O)=C(C\C=C(/C)CCC=C(C)C)C(O)=C1 QXACEHWTBCFNSA-SFQUDFHCSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- QXACEHWTBCFNSA-UHFFFAOYSA-N cannabigerol Natural products CCCCCC1=CC(O)=C(CC=C(C)CCC=C(C)C)C(O)=C1 QXACEHWTBCFNSA-UHFFFAOYSA-N 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000004071 biological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Antidote compositions are disclosed that contain cannabigerol (CBG) and/or tetrahydrocannabivarin (THCV) that can be used to offset THC-induced biological effects, particularly for THC-containing edibles.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063108008P | 2020-10-30 | 2020-10-30 | |
US63/108,008 | 2020-10-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2022090807A2 WO2022090807A2 (en) | 2022-05-05 |
WO2022090807A3 true WO2022090807A3 (en) | 2022-06-16 |
Family
ID=81384473
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2021/000776 WO2022090807A2 (en) | 2020-10-30 | 2021-11-01 | Cannabigerol and tetrahydrocannabivarin antidote formulations and methods of using the same |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2022090807A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024015915A2 (en) * | 2022-07-14 | 2024-01-18 | Taac Naturals Enterprises, Llc | Cannabinoid formulations |
-
2021
- 2021-11-01 WO PCT/IB2021/000776 patent/WO2022090807A2/en active Application Filing
Non-Patent Citations (3)
Title |
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CRIPPA J ET AL.: "Pharmacological interventions in the treatment of the acute effects of cannabis: a systemic review of literature", HARM REDUCTION JOURNA L, vol. 9, no. 7, 25 January 2012 (2012-01-25), XP021118638, ISSN: 1477- 7517, [retrieved on 20220413], DOI: 10.1186/1477-7517-9-7 * |
SKOLNICK PHIL; CRYSTAL ROGER: "Cannabinoid(CB-1) receptor antagonists: a molecular approach to treating acute cannabinoid overdose", JOURNAL OF NEURAL TRANSMISSION, SPRINGER VIENNA, VIENNA, vol. 127, no. 2, 31 December 2019 (2019-12-31), Vienna, pages 279 - 286, XP037029319, ISSN: 0300-9564, DOI: 10.1007/s00702-019-02132-7 * |
VEMURI KIRAN, RAGHAV JIMIT, MAKRIYANNIS ALEXANDROS: "Antidotes for Acute Cannabinoid Intoxication", THE FASEB JOURNAL, vol. 33, no. S1, 1 April 2019 (2019-04-01), US, pages 804.2 - 804.2, XP009537367, ISSN: 0892-6638, DOI: 10.1096/fasebj.2019.33.1_supplement.804.2 * |
Also Published As
Publication number | Publication date |
---|---|
WO2022090807A2 (en) | 2022-05-05 |
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