WO2022083124A1 - Personalized diabetes health management system and device, and storage medium - Google Patents

Personalized diabetes health management system and device, and storage medium Download PDF

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Publication number
WO2022083124A1
WO2022083124A1 PCT/CN2021/097230 CN2021097230W WO2022083124A1 WO 2022083124 A1 WO2022083124 A1 WO 2022083124A1 CN 2021097230 W CN2021097230 W CN 2021097230W WO 2022083124 A1 WO2022083124 A1 WO 2022083124A1
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blood glucose
mode
data
patient
blood
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PCT/CN2021/097230
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French (fr)
Chinese (zh)
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赵婷婷
孙行智
廖希洋
赵惟
徐卓扬
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平安科技(深圳)有限公司
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/044Recurrent networks, e.g. Hopfield networks
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/045Combinations of networks
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Definitions

  • the present application relates to the field of artificial intelligence technology and the field of digital medicine, and in particular to a personalized diabetes health management system, equipment and storage medium.
  • Diabetes is a long-term chronic disease that requires long-term adherence to treatment and management. Patients' daily behavior and self-management ability are one of the keys to diabetes control. Therefore, in addition to drug treatment, diabetes control requires individualized lifestyle interventions, including diet, exercise, and self-monitoring of blood sugar.
  • Chinese patent CN110680340A discloses an all-weather blood glucose monitoring system for diabetes health management, which collects blood glucose data by setting a blood glucose acquisition module including a graphene flexible glucose sensor attached to the wrist, and then directly determines through the early warning module Whether the collected data falls into the preset alarm threshold, and then give an early warning, the early warning of this patent is the current early warning.
  • a diet monitoring module and a food blood sugar calculation module it does not involve other aspects of management, and blood sugar early warning The accuracy of the results also needs to be improved.
  • the purpose of this application is to provide a personalized diabetes health management system, equipment and storage medium to solve the problems in the prior art that the diabetes health management system lacks individualization, management is not comprehensive, and blood glucose warning information is not accurate enough.
  • the present application provides a personalized diabetes health management system, comprising:
  • a blood sugar prediction unit configured to input the blood sugar data into a blood sugar prediction model for prediction, and output a blood sugar prediction value in a future period of time through the blood sugar prediction model, wherein the blood sugar prediction model is performed in the mode by adopting The patient's own data is trained;
  • a comparison unit configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
  • an electronic device provided by the present application includes:
  • the memory stores instructions executable by the at least one processor, the instructions being executed by the at least one processor to enable the at least one processor to execute the following elements and / or the function of the module:
  • a data acquisition unit configured to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient with time series changes in the mode, wherein the mode includes: a sleep mode, a diet mode, an exercise mode and a leisure mode;
  • a comparison unit configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
  • the present application further provides a computer-readable storage medium storing a computer program, and when the computer program is executed by a processor, realizes the following units and/or modules in the personalized diabetes health management system Features:
  • a data acquisition unit configured to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient with time series changes in the mode, wherein the mode includes: a sleep mode, a diet mode, an exercise mode and a leisure mode;
  • a blood sugar prediction unit configured to input the blood sugar data into a blood sugar prediction model for prediction, and output a blood sugar prediction value in a future period of time through the blood sugar prediction model, wherein the blood sugar prediction model is performed in the mode by adopting The patient's own data is trained;
  • a comparison unit configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
  • the personalized diabetes health management system, device and storage medium of the present application are obtained based on technologies such as predictive analysis of artificial intelligence, health management and risk assessment of digital medicine.
  • the application collects and monitors blood glucose data in four different modes, and inputs the blood glucose data in each mode into the blood glucose prediction model trained in this mode using the patient's own blood glucose data for prediction, and finally outputs the future time period.
  • the blood sugar prediction value is compared with the preset threshold value, and an early warning signal is issued according to the comparison result, which makes the blood sugar management more comprehensive, and the blood sugar early warning result is more accurate. need.
  • FIG. 1 is a schematic diagram of the use of the personalized diabetes health management system according to an embodiment of the present application.
  • FIG. 2 is a schematic diagram of the operation process framework of the personalized diabetes health management system according to an embodiment of the present application
  • FIG. 3 is a schematic diagram of a sliding window in a data processing module according to an embodiment of the present application.
  • FIG. 4 is a schematic diagram of the framework structure of an embodiment of the present application using LSTM to build a blood glucose prediction model
  • FIG. 5 is a schematic diagram of a layer structure of a blood glucose prediction model constructed using LSTM according to an embodiment of the present application
  • FIG. 6 is a schematic structural diagram of a personalized diabetes health management system according to an embodiment of the present application.
  • FIG. 7 is a schematic structural diagram of an electronic device according to an embodiment of the present application.
  • the present application provides a personalized diabetes health management system, including: a data acquisition unit, a blood glucose prediction unit, and a comparison unit.
  • the system realizes personalized diabetes health management, and the management is more comprehensive, and the blood sugar warning information is more accurate, which can promote patients to develop good living habits, thereby improving their health status.
  • the data acquisition unit is used to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient that changes in time in the mode.
  • the data acquisition unit may, for example, collect blood glucose data of time series in each mode by wearing a blood glucose meter by a patient.
  • the mode may reflect the current activities performed by the patient, and the mode may include sleep mode, eating mode, exercise mode, leisure mode, and the like.
  • this application provides blood sugar intervention in multiple modes, covering the diet, exercise, sleep and rest modes of diabetic patients.
  • Monitoring blood sugar in each mode can make blood sugar alarm information more accurate, so that health management and prediction results are more comprehensive and accurate, that is, providing a more comprehensive diabetes management model for diabetic patients, which is helpful to improve the self-management ability of patients.
  • Foster healthy lifestyles that ultimately improve their clinical outcomes, health status, and quality of life. It should be noted that the mode described in this application is not limited to this, for example, the mode of medication may also be included.
  • the blood glucose prediction unit is used for inputting the blood glucose data into a blood glucose prediction model for prediction, and the blood glucose prediction model outputs a blood glucose prediction value in a future period of time, wherein the blood glucose prediction model is performed in the mode by using the patient It is obtained by training its own data, and a personalized prediction model is trained according to the personalized data, which fully reflects the personalized blood sugar management method, so as to realize the personalized diabetes health management system.
  • the future period of time is a preset future period of time, such as 0.5 to 4 hours in the future.
  • the blood glucose data input by the blood glucose prediction model is the blood glucose data of the time series change from time T to T+t
  • the output blood glucose prediction value is the average value of the blood glucose prediction sequence from T+t to T+t+ ⁇ t, where ⁇ t is the average value of the blood glucose prediction sequence.
  • the specific value can be determined according to the patient's living habits and the characteristics of blood sugar changes, for example, it can be 3 to 4 hours.
  • the comparison unit is used for comparing the predicted blood glucose value with a preset blood glucose abnormality threshold, and if the blood glucose predicted value exceeds the blood glucose abnormality threshold, an early warning reminder is issued.
  • the threshold for abnormal blood glucose varies with different activity modes, and it can also vary from person to person.
  • the threshold for abnormal blood glucose is preset through the threshold setting module.
  • the threshold Modify the settings module if the patient needs to customize the threshold, it can also pass the threshold Modify the settings module.
  • the lowest blood glucose threshold and the highest blood glucose threshold in the sleep mode and in the exercise mode can be preset through the threshold setting unit according to the patient's own conditions.
  • the personalized model and personalized early warning threshold of the present application can meet the daily blood sugar management of diabetic patients, and avoid the risk of serious hypoglycemia events or hyperglycemia.
  • FIG. 1 schematically shows a schematic diagram of the use of the personalized diabetes health management system of the embodiment
  • FIG. 2 schematically shows the operation process framework of the personalized diabetes health management system of the embodiment.
  • Figure 1 includes: a mobile smart terminal (smart phone), a Bluetooth electronic scale, a continuous blood glucose meter and a smart bracelet connected through a network.
  • a mobile smart terminal smart phone
  • Bluetooth electronic scale a continuous blood glucose meter
  • a smart bracelet connected through a network.
  • using the mobile intelligent terminal can complete the input of the patient's basic information and the calling of the blood glucose prediction model, and at the same time, the function setting of the system can be completed, and it is also used to send out alarm information.
  • the smart bracelet can receive alarm information, and at the same time, it can record the movement data of the patient in the movement mode.
  • the continuous blood glucose meter is used to dynamically collect real-time blood glucose data of a patient and upload it to a mobile intelligent terminal for data processing, model building, prediction and other operations.
  • the bluetooth electronic scale with bluetooth function can be used to collect the patient's diet data and upload it to the mobile smart terminal.
  • the blood sugar of the patient will fluctuate greatly within a day. For example, the blood sugar after meals may exceed 10mmol/L, and when hypoglycemia occurs, the blood sugar can be as low as 3.9mmol/L.
  • the personalized diabetes health management system of this application can be used in different The blood sugar is monitored separately in the mode, and then predicted by the blood sugar prediction model in the corresponding mode, so that the blood sugar alarm prediction information is more accurate.
  • the system may further include an input and call unit for inputting basic patient information, and calling a blood glucose prediction model trained by using the patient's own blood glucose data according to the patient's basic information.
  • the basic information may include: patient name, gender, date of birth, body mass index BMI, and the like.
  • the patient logs into the personalized diabetes health management system through a mobile smart terminal, and basic information needs to be entered when using it for the first time; then select the corresponding mode to train the blood glucose prediction model according to the patient's daily activities or the time period in between, or Directly enter the health management state to predict blood sugar through the blood sugar prediction model, and finally make an alarm reminder through mobile smart terminals or smart bracelets after the comparison.
  • the present application further ensures that the blood glucose prediction model corresponds to the patient one-to-one by calling the blood glucose prediction model belonging to the individual patient (that is, the model obtained by using the patient's own data) according to the basic information of the patient, so that the subsequent blood glucose prediction results are more personalized. meet the needs of different patients.
  • the personalized diabetes health management system further includes: a model building unit for building blood glucose prediction models in different modes by using the LSTM algorithm.
  • the model building process in the model building process, the model building process in each mode is the same, and the difference is the parameters for building the model and the data of the model (the data are different because they are collected under different moduli).
  • the present application proposes to use the patient's own blood glucose data to train the blood glucose prediction model, and use different prediction models in different modes. Added personalization so that blood glucose predictions not only behave differently on an individual basis, but also in different modes.
  • LSTM longshort-term memory
  • time series series that is, data that can process changes in the sequence.
  • Figure 4 schematically shows the framework structure of LSTM. As shown in Figure 4, it is controlled by a forget gate z f , an input gate z i , and an output gate zo , selectively forget the input from the previous node, and selectively forget the input of this stage. Memory, add these two parts to get ct that is transmitted to the next state, the output stage will decide which information will be regarded as the output of the current state, controlled by zo, get h t . The final output y t is obtained by transforming h t .
  • Fig. 5 schematically shows the layer structure of LSTM, as shown in Fig. 5 , including input layer (X1, X2... Xt ), LSTM layer (A1, A2...At; h1, h2...ht ), and the output layer (y 1 , y 2 , ... y t ); the input is the processed time series blood glucose data, and the output is the blood glucose data of the next period.
  • the model building unit may include: a data processing module, a model training module, a model verification module, and the like.
  • the data processing module is used to process the blood sugar data in a sliding window manner; wherein, the blood sugar data is the blood sugar data of the patient's own time series changes in each mode collected by the data acquisition unit.
  • FIG. 3 schematically shows the structure of the sliding window, and the sliding window method is adopted, which can increase the training data.
  • the length of the sliding window T represents the length of each time step s, which is the length of the input X.
  • the data processing module is also used for dividing the blood glucose data into two parts, one part is used for the model training module to train the blood glucose prediction model, and the other part is used for the model verification module to verify the blood glucose prediction model. For example, blood glucose data can be split into 80% for training and 20% for validation.
  • the model training module uses the processed blood glucose data of the patient to train the blood glucose prediction model; wherein, different blood glucose prediction models are obtained by training the blood glucose data in different modes. That is to say, in order to train a personalized blood glucose prediction model, the patient needs to use it for a period of time in advance, such as a month, and use the data acquisition unit to collect the blood glucose data of the patient's blood sugar changes in different modes for model training, so as to fully reflect the personalized In the same way, during the use process, the training of the blood glucose prediction models in different modes uses the blood glucose data of the patient in the corresponding mode. As for the mode, the present application can switch the mode according to the patient's own activities, and can also switch the mode according to the time.
  • the mode can be determined according to the activity performed by the patient when the blood glucose data is collected.
  • the patient can switch the mode according to the current activity, and combine the mode with the blood glucose data collected in this mode. Upload, so as to label the blood sugar data later, so as to improve the prediction accuracy of the model; of course, the mode can also be determined according to the time period when the blood sugar data is collected.
  • the blood sugar data can be determined according to the time period.
  • the mode is set to the default state, that is, when the user does not switch the mode selection, the system switches the mode according to the time, for example, 00:00:00-06:00:00 belongs to the sleep mode.
  • the model verification module uses the processed blood glucose data of the patient to verify the blood glucose prediction model. If the error between the predicted value and the actual value is within the threshold, the blood glucose prediction model is constructed. That is, the error between the actual value and the predicted value of the blood glucose data in the next period is tested on 20% of the data. Specifically, the verification is carried out according to 20% of the blood glucose data. If the error is within the threshold (allowed range), the model verification is passed, then The blood glucose prediction model trained in the corresponding mode can be obtained. If the error is not within the threshold, it is necessary to continue training and verify the blood glucose prediction model until the model is verified and the trained model is obtained.
  • the data collection unit further includes: a data labeling module.
  • a data labeling module When the model is built, the data needs to be labeled during the data collection process, that is, the mode label and the abnormal occurrence label are required, so that the subsequent model training can be carried out.
  • the data labeling module is used to label the mode in which the blood glucose data is located to obtain the mode label, and at the same time, it is used to label the abnormal situation of the blood glucose data to obtain the abnormality occurrence label, and the mode label and the abnormality label are obtained.
  • the occurrence label is uploaded to the model building unit to construct and train the blood glucose prediction model.
  • the mode in which the blood glucose data is located may be marked according to the activities performed by the patient when the blood glucose data is collected, or according to the time period in which the blood glucose data is collected. In addition, if the user does not select the mode, the time period may be used by default to determine the mode of the blood glucose data.
  • the mode label includes exercise mode label, sleep mode label, diet mode label, and leisure mode label.
  • the blood glucose data collected when the patient is exercising is labeled as the exercise mode label, and 00:00:00-06:00:
  • the blood glucose data obtained in the 00 period is marked as the sleep mode label.
  • the abnormality label may include: low blood sugar label, high blood sugar label, etc. For example, when low blood sugar or high blood sugar occurs, the user can return to the abnormal label through the smart device (for example, click the abnormal report button on the smart bracelet), In this way, the blood glucose data has the mode label and the abnormal occurrence label.
  • the personalized diabetes health management system may further include: a calorie reminder unit, configured to acquire the type of food in the eating mode, calculate the calorie of the food, and determine whether the calorie of the food exceeds a preset calorie threshold, If it exceeds, a reminder of unreasonable diet will be issued.
  • a calorie reminder unit configured to acquire the type of food in the eating mode, calculate the calorie of the food, and determine whether the calorie of the food exceeds a preset calorie threshold, If it exceeds, a reminder of unreasonable diet will be issued.
  • a calorie reminder unit configured to acquire the type of food in the eating mode, calculate the calorie of the food, and determine whether the calorie of the food exceeds a preset calorie threshold, If it exceeds, a reminder of unreasonable diet will be issued.
  • the type of food including staple food, vegetables, fruit, meat, etc.
  • the calorie reminder unit is configured to determine whether the calorie difference exceeds a preset calorie threshold, and if it exceeds, a reminder of unreasonable diet is issued.
  • the calorie difference refers to the difference between the food calorie in the eating mode and the calorie consumed in the exercise mode.
  • FIG. 6 schematically shows the structure of the personalized diabetes health management system according to the embodiment of the present application.
  • the personalized diabetes health management system of the present application when the model is constructed: the patient information is entered through the entry calling unit; The acquisition unit collects the blood glucose data of the same patient in different modes, and uses the data labeling module for labeling; and then enters the model building unit, uses the data processing module to process the data, and inputs the processed data to the model training module and model verification module. Carry out model training and verification, and finally obtain a trained blood glucose prediction model.
  • the blood glucose prediction value in the future time period can be output and based on the difference between the blood glucose prediction value and the threshold value
  • the comparison results are used to issue early warning signals, which makes blood sugar management more comprehensive, and the blood sugar early warning results are more accurate.
  • Personalized blood sugar management can be realized, which can meet the needs of all kinds of diabetic patients.
  • FIG. 7 is a schematic structural diagram of an electronic device implementing a management program in the present application.
  • the electronic device 1 may include a processor 10, a memory 11 and a bus, and may also include a computer program stored in the memory 11 and executed on the processor 10, such as a management program 12 .
  • the memory 11 includes at least one type of readable storage medium, and the readable storage medium includes flash memory, mobile hard disk, multimedia card, card-type memory (for example: SD or DX memory, etc.), magnetic memory, magnetic disk, CD etc.
  • the memory 11 may be an internal storage unit of the electronic device 1 in some embodiments, such as a mobile hard disk of the electronic device 1 .
  • the memory 11 may also be an external storage device of the electronic device 1, such as a pluggable mobile hard disk, a smart memory card (Smart Media Card, SMC), a secure digital (Secure Digital) equipped on the electronic device 1. , SD) card, flash memory card (Flash Card), etc.
  • the memory 11 may also include both an internal storage unit of the electronic device 1 and an external storage device.
  • the memory 11 can not only be used to store application software installed in the electronic device 1 and various types of data, such as codes of management programs, etc., but also can be used to temporarily store data that has been output or will be output.
  • the processor 10 may be composed of integrated circuits, for example, may be composed of a single packaged integrated circuit, or may be composed of multiple integrated circuits packaged with the same function or different functions, including one or more integrated circuits.
  • Central Processing Unit CPU
  • microprocessor digital processing chip
  • graphics processor and combination of various control chips, etc.
  • the processor 10 is the control core (Control Unit) of the electronic device, and uses various interfaces and lines to connect the various components of the entire electronic device, by running or executing programs or modules (such as management and control) stored in the memory 11. programs, etc.), and call data stored in the memory 11 to execute various functions of the electronic device 1 and process data.
  • the bus may be a peripheral component interconnect (PCI for short) bus or an extended industry standard architecture (Extended industry standard architecture, EISA for short) bus or the like.
  • PCI peripheral component interconnect
  • EISA Extended industry standard architecture
  • the bus can be divided into address bus, data bus, control bus and so on.
  • the bus is configured to implement connection communication between the memory 11 and at least one processor 10 and the like.
  • FIG. 7 only shows an electronic device with components, and those skilled in the art can understand that it does not constitute a limitation on the electronic device 1, and may include fewer or more components than the one shown, or a combination of certain components may be included. some components, or a different arrangement of components.
  • the electronic device 1 may also include a power supply (such as a battery) for powering the various components, preferably, the power supply may be logically connected to the at least one processor 10 through a power management device, so that the power management
  • the device implements functions such as charge management, discharge management, and power consumption management.
  • the power source may also include one or more DC or AC power sources, recharging devices, power failure detection circuits, power converters or inverters, power status indicators, and any other components.
  • the electronic device 1 may further include various sensors, Bluetooth modules, Wi-Fi modules, etc., which will not be repeated here.
  • the electronic device 1 may also include a network interface, optionally, the network interface may include a wired interface and/or a wireless interface (such as a WI-FI interface, a Bluetooth interface, etc.), which is usually used in the electronic device 1 Establish a communication connection with other electronic devices.
  • a network interface optionally, the network interface may include a wired interface and/or a wireless interface (such as a WI-FI interface, a Bluetooth interface, etc.), which is usually used in the electronic device 1 Establish a communication connection with other electronic devices.
  • the electronic device 1 may further include a user interface, and the user interface may be a display (Display), an input unit (eg, a keyboard (Keyboard)), optionally, the user interface may also be a standard wired interface or a wireless interface.
  • the display may be an LED display, a liquid crystal display, a touch-sensitive liquid crystal display, an OLED (Organic Light-Emitting Diode, organic light-emitting diode) touch device, and the like.
  • the display may also be appropriately called a display screen or a display unit, which is used for displaying information processed in the electronic device 1 and for displaying a visualized user interface.
  • the management program 12 stored in the memory 11 in the electronic device 1 is a combination of multiple instructions, and when running in the processor 10, the functions of each unit and/or module can be implemented, for example: for obtaining a patient A data acquisition unit that collects the blood glucose data of the patient in the mode and the time series changes in the mode; used to input the blood glucose data into the blood glucose prediction model for prediction, and the blood glucose prediction model outputs the blood glucose prediction value for a period of time in the future The blood glucose prediction unit; a comparison unit for comparing the blood glucose prediction value with a preset blood glucose abnormality threshold, and issuing an early warning if the blood glucose prediction value exceeds the blood glucose abnormality threshold.
  • the modules/units integrated by the electronic device 1 are implemented in the form of software functional units and sold or used as independent products, they can be stored in a computer-readable storage medium, and the computer-readable storage medium Can be non-volatile or volatile.
  • the computer-readable storage medium can be any tangible medium that contains or stores programs or instructions, on which a computer program that can be executed is stored. When the computer program is executed by the processor, the stored program instructs the relevant hardware through the stored program. The functions of each unit/module of the personalized diabetes health management system of the present application are realized.
  • the stored program instructs the relevant hardware to obtain the mode the patient is in and collect the blood glucose data of the patient's time-series changes in the mode, input the blood glucose data into the blood glucose prediction model for prediction, and the blood glucose prediction model outputs the future The predicted blood glucose value within a period of time, compares the predicted blood glucose value with a preset blood glucose abnormality threshold, and issues a warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
  • the computer-readable medium may include: any entity or device capable of carrying the computer program code, recording medium, U disk, removable hard disk, magnetic disk, optical disk, computer memory, read-only memory (ROM, Read-Only Memory) Memory).
  • modules described as separate components may or may not be physically separated, and components shown as modules may or may not be physical units, that is, may be located in one place, or may be distributed to multiple network units. Some or all of the modules may be selected according to actual needs to achieve the purpose of the solution in this embodiment.
  • each functional module in each embodiment of the present application may be integrated into one processing unit, or each unit may exist physically alone, or two or more units may be integrated into one unit.
  • the above-mentioned integrated units can be implemented in the form of hardware, or can be implemented in the form of hardware plus software function modules.

Abstract

Provided are a personalized diabetes health management system and device, and a storage medium. The system comprises: a data collection unit used for acquiring the mode in which a patient is in and collecting blood glucose data of time-series changes of the patient in said mode, the mode comprising sleep, diet, exercise and leisure modes; a blood glucose prediction unit used for inputting the blood glucose data into a blood glucose prediction model to predict and output a predicted blood glucose value in a future period of time, wherein the blood glucose prediction model is obtained by training by means of using the patient's own data in the mode; and a comparison unit used for comparing the predicted blood glucose value with a preset abnormal blood glucose threshold, wherein if the predicted blood glucose value exceeds the abnormal blood glucose threshold, an early warning reminder is issued. Personalized diabetes health management can be achieved, the management is more comprehensive, and blood glucose warning information is more accurate.

Description

个性化糖尿病健康管理系统、设备及存储介质Personalized diabetes health management system, device and storage medium
本申请要求于2020年10月22日提交中国专利局、申请号为202011138904.2,发明名称为“个性化糖尿病健康管理系统、设备及存储介质”的中国专利申请的优先权,其全部内容通过引用结合在本申请中。This application claims the priority of the Chinese patent application with the application number 202011138904.2 and the invention titled "Personalized Diabetes Health Management System, Device and Storage Medium" filed with the China Patent Office on October 22, 2020, the entire contents of which are incorporated by reference in this application.
技术领域technical field
本申请涉及人工智能技术领域以及数字医疗领域,特别是涉及一种个性化糖尿病健康管理系统、设备及存储介质。The present application relates to the field of artificial intelligence technology and the field of digital medicine, and in particular to a personalized diabetes health management system, equipment and storage medium.
背景技术Background technique
糖尿病是一种长期慢性疾病,需要长期坚持治疗和管理。患者日常行为和自我管理能力是糖尿病控制与否的关键之一,因此,糖尿病的控制除了药物上的治疗外还需要个性化的生活方式的干预措施,包括饮食、运动、自我血糖监测等内容。Diabetes is a long-term chronic disease that requires long-term adherence to treatment and management. Patients' daily behavior and self-management ability are one of the keys to diabetes control. Therefore, in addition to drug treatment, diabetes control requires individualized lifestyle interventions, including diet, exercise, and self-monitoring of blood sugar.
其中,对于饮食:糖尿病患者需要控制饮食以维持标准体重、纠正已发生的代谢紊乱和减轻胰岛β细胞的负担,每天摄入的营养总量有一定标准,帮助糖尿病患者计算和统计各类物质摄入量有助于健康饮食计划的建立。对于运动:个性化的运动方案可以促进糖尿病患者坚持运动治疗,改善身体状况。对于自我血糖监测:患者在治疗过程中可能发生血糖过低现象,低血糖可导致不适甚至生命危险,也是血糖达标的主要障碍,如果能够在发生低血糖之前发出预警,及时采取措施,那就可以很大程度降低患者的低血糖风险。Among them, for diet: diabetic patients need to control their diet to maintain a standard body weight, correct metabolic disorders that have occurred, and reduce the burden on islet beta cells. The total daily intake of nutrients has a certain standard to help diabetic patients calculate and count the intake of various substances. Intakes help in the establishment of a healthy eating plan. For exercise: A personalized exercise program can promote diabetes patients to adhere to exercise therapy and improve their physical condition. For self-monitoring of blood sugar: patients may experience hypoglycemia during treatment. Hypoglycemia can lead to discomfort and even life-threatening, and is also the main obstacle to reaching the blood sugar target. Greatly reduces the risk of hypoglycemia in patients.
发明人意识到现有的糖尿病管理系统大多只有血糖监测模块,缺少多方面的生活方式上的管理,同时,现有糖尿病管理系统缺乏个性化,不能满足各类糖尿病患者的需求。例如,中国专利CN110680340A公开了一种用于糖尿病健康管理的全天候血糖监测系统,其通过设置包含贴覆在手腕上的石墨烯柔性葡萄糖传感器的血糖采集模块进行血糖数据采集,接着通过预警模块直接判定采集数据是否落入预设报警门限,然后进行预警,该专利其预警为当前预警,虽然其还公开了饮食监测模块和用于食品血糖计算模块,但并未涉及其他方面的管理,且血糖预警结果的准确性也有待提高。The inventor realizes that most of the existing diabetes management systems only have a blood glucose monitoring module, which lacks various lifestyle management. At the same time, the existing diabetes management systems lack individualization and cannot meet the needs of various types of diabetes patients. For example, Chinese patent CN110680340A discloses an all-weather blood glucose monitoring system for diabetes health management, which collects blood glucose data by setting a blood glucose acquisition module including a graphene flexible glucose sensor attached to the wrist, and then directly determines through the early warning module Whether the collected data falls into the preset alarm threshold, and then give an early warning, the early warning of this patent is the current early warning. Although it also discloses a diet monitoring module and a food blood sugar calculation module, it does not involve other aspects of management, and blood sugar early warning The accuracy of the results also needs to be improved.
发明内容SUMMARY OF THE INVENTION
基于上述问题,本申请的目的在于提供一种个性化糖尿病健康管理系统、设备及存储介质,以解决现有技术中糖尿病健康管理系统缺乏个性化,管理不全面,血糖预警信息不够准确的问题。Based on the above problems, the purpose of this application is to provide a personalized diabetes health management system, equipment and storage medium to solve the problems in the prior art that the diabetes health management system lacks individualization, management is not comprehensive, and blood glucose warning information is not accurate enough.
上述目的是通过以下技术方案实现的:The above purpose is achieved through the following technical solutions:
根据本申请的一个方面,本申请提供一种个性化糖尿病健康管理系统,包括:According to one aspect of the present application, the present application provides a personalized diabetes health management system, comprising:
数据采集单元,用于获取患者所处的模式,并采集患者在所述模式下时序变化的血糖数据,其中,所述模式包括:睡眠模式、饮食模式、运动模式和休闲模式;a data acquisition unit, configured to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient with time series changes in the mode, wherein the mode includes: a sleep mode, a diet mode, an exercise mode and a leisure mode;
血糖预测单元,用于将所述血糖数据输入到血糖预测模型中进行预测,并通过血糖预测模型输出未来一段时间内的血糖预测值,其中,所述血糖预测模型是在所述模式下通过采用患者自身的数据进行训练得到;A blood sugar prediction unit, configured to input the blood sugar data into a blood sugar prediction model for prediction, and output a blood sugar prediction value in a future period of time through the blood sugar prediction model, wherein the blood sugar prediction model is performed in the mode by adopting The patient's own data is trained;
比较单元,用于比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值,则发出预警提醒。A comparison unit, configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
根据本申请的另一个方面,本申请提供的一种电子设备,包括:According to another aspect of the present application, an electronic device provided by the present application includes:
至少一个处理器;以及,at least one processor; and,
与所述至少一个处理器通信连接的存储器;其中,a memory communicatively coupled to the at least one processor; wherein,
所述存储器存储有可被所述至少一个处理器执行的指令,所述指令被所述至少一个处理器执行,以使所述至少一个处理器能够执行个性化糖尿病健康管理系统中如下各单元和/或模块的功能:The memory stores instructions executable by the at least one processor, the instructions being executed by the at least one processor to enable the at least one processor to execute the following elements and / or the function of the module:
数据采集单元,用于获取患者所处的模式,并采集患者在所述模式下时序变化的血糖数据,其中,所述模式包括:睡眠模式、饮食模式、运动模式和休闲模式;a data acquisition unit, configured to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient with time series changes in the mode, wherein the mode includes: a sleep mode, a diet mode, an exercise mode and a leisure mode;
血糖预测单元,用于将所述血糖数据输入到血糖预测模型中进行预测,并通过血糖预测模型输出未来一段时间内的血糖预测值,其中,所述血糖预测模型是在所述模式下通过采用患者自身的数据进行训练得到;A blood sugar prediction unit, configured to input the blood sugar data into a blood sugar prediction model for prediction, and output a blood sugar prediction value in a future period of time through the blood sugar prediction model, wherein the blood sugar prediction model is performed in the mode by adopting The patient's own data is trained;
比较单元,用于比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值,则发出预警提醒。A comparison unit, configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
根据本申请的还一个方面,本申请还提供一种计算机可读存储介质,存储有计算机程序,所述计算机程序被处理器执行时实现个性化糖尿病健康管理系统中如下各单元和/或模块的功能:According to yet another aspect of the present application, the present application further provides a computer-readable storage medium storing a computer program, and when the computer program is executed by a processor, realizes the following units and/or modules in the personalized diabetes health management system Features:
数据采集单元,用于获取患者所处的模式,并采集患者在所述模式下时序变化的血糖数据,其中,所述模式包括:睡眠模式、饮食模式、运动模式和休闲模式;a data acquisition unit, configured to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient with time series changes in the mode, wherein the mode includes: a sleep mode, a diet mode, an exercise mode and a leisure mode;
血糖预测单元,用于将所述血糖数据输入到血糖预测模型中进行预测,并通过血糖预测模型输出未来一段时间内的血糖预测值,其中,所述血糖预测模型是在所述模式下通过采用患者自身的数据进行训练得到;A blood sugar prediction unit, configured to input the blood sugar data into a blood sugar prediction model for prediction, and output a blood sugar prediction value in a future period of time through the blood sugar prediction model, wherein the blood sugar prediction model is performed in the mode by adopting The patient's own data is trained;
比较单元,用于比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值,则发出预警提醒。A comparison unit, configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
与现有技术相比,本申请个性化糖尿病健康管理系统、设备及存储介质是基于人工智能的预测分析、数字医疗的健康管理和风险评估等技术得到的。本申请在四种不同模式下进行血糖数据采集和监测,并将各模式下血糖数据输入到采用患者自身的血糖数据在该模式下训练好的血糖预测模型中进行预测,最终输出未来时间段内的血糖预测值,将其与预先设置的阈值比较,并根据比较结果发出预警信号,使得血糖管理更加全面,血糖预警结 果更加精确,且实现了个性化的血糖管理,可以满足各类糖尿病患者的需求。Compared with the prior art, the personalized diabetes health management system, device and storage medium of the present application are obtained based on technologies such as predictive analysis of artificial intelligence, health management and risk assessment of digital medicine. The application collects and monitors blood glucose data in four different modes, and inputs the blood glucose data in each mode into the blood glucose prediction model trained in this mode using the patient's own blood glucose data for prediction, and finally outputs the future time period. The blood sugar prediction value is compared with the preset threshold value, and an early warning signal is issued according to the comparison result, which makes the blood sugar management more comprehensive, and the blood sugar early warning result is more accurate. need.
附图说明Description of drawings
通过参考以下结合附图的说明,并且随着对本申请的更全面理解,本申请的其它目的及结果将更加明白及易于理解。附图中:Other objects and results of the present application will be more apparent and readily understood by reference to the following description in conjunction with the accompanying drawings, and as the present application is more fully understood. In the attached picture:
图1是本申请实施例的个性化糖尿病健康管理系统的使用示意图;1 is a schematic diagram of the use of the personalized diabetes health management system according to an embodiment of the present application;
图2是本申请实施例的个性化糖尿病健康管理系统运行流程框架示意图;FIG. 2 is a schematic diagram of the operation process framework of the personalized diabetes health management system according to an embodiment of the present application;
图3是本申请实施例的数据处理模块中滑动窗口的示意图;3 is a schematic diagram of a sliding window in a data processing module according to an embodiment of the present application;
图4是本申请实施例的采用LSTM构建血糖预测模型的框架结构示意图;4 is a schematic diagram of the framework structure of an embodiment of the present application using LSTM to build a blood glucose prediction model;
图5是本申请实施例的采用LSTM构建血糖预测模型的层结构示意图;5 is a schematic diagram of a layer structure of a blood glucose prediction model constructed using LSTM according to an embodiment of the present application;
图6是本申请实施例个性化糖尿病健康管理系统的结构示意图;6 is a schematic structural diagram of a personalized diabetes health management system according to an embodiment of the present application;
图7是本申请实施例电子设备的结构示意图。FIG. 7 is a schematic structural diagram of an electronic device according to an embodiment of the present application.
具体实施方式Detailed ways
下面将结合本申请实施例中的附图,对本申请实施例中的技术方案进行清楚、完整地描述:The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application:
本申请提供一种个性化糖尿病健康管理系统,包括:数据采集单元、血糖预测单元、以及比较单元。该系统实现了个性化的糖尿病健康管理,且管理更加全面,血糖预警信息更加准确,能够促进患者养成良好的生活习惯,从而改善健康状态。The present application provides a personalized diabetes health management system, including: a data acquisition unit, a blood glucose prediction unit, and a comparison unit. The system realizes personalized diabetes health management, and the management is more comprehensive, and the blood sugar warning information is more accurate, which can promote patients to develop good living habits, thereby improving their health status.
本申请中,所述数据采集单元用于获取患者所处的模式,并采集患者在所述模式下时序变化的血糖数据。所述数据采集单元例如可以通过患者佩戴动态血糖仪采集各个模式下的时间序列的血糖数据。所述模式可以体现患者当前所进行的活动,所述模式可以包括:睡眠模式、饮食模式、运动模式和休闲模式等。为了合理的检测血糖,本申请提供了多个模式下的血糖干预,涵盖糖尿病患者的饮食、运动、睡眠和休息模式等,各模式下,患者的血糖变化不同,且差异可能较大,在四种模式下分别去监测血糖,可以让血糖警报信息更加准确,从而使得健康管理和预测结果更加全面、准确,即为糖尿病患者提供比较全面的糖尿病管理模式,有助于提升患者的自我管理能力,培养健康的生活方式,最终改善其临床结局、健康状况和生活质量。需要说明的是,本申请所述模式不限于此,例如还可以包括用药模式等。In the present application, the data acquisition unit is used to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient that changes in time in the mode. The data acquisition unit may, for example, collect blood glucose data of time series in each mode by wearing a blood glucose meter by a patient. The mode may reflect the current activities performed by the patient, and the mode may include sleep mode, eating mode, exercise mode, leisure mode, and the like. In order to detect blood sugar reasonably, this application provides blood sugar intervention in multiple modes, covering the diet, exercise, sleep and rest modes of diabetic patients. Monitoring blood sugar in each mode can make blood sugar alarm information more accurate, so that health management and prediction results are more comprehensive and accurate, that is, providing a more comprehensive diabetes management model for diabetic patients, which is helpful to improve the self-management ability of patients. Foster healthy lifestyles that ultimately improve their clinical outcomes, health status, and quality of life. It should be noted that the mode described in this application is not limited to this, for example, the mode of medication may also be included.
所述血糖预测单元用于将所述血糖数据输入到血糖预测模型中进行预测,血糖预测模型输出未来一段时间内的血糖预测值,其中,所述血糖预测模型是在所述模式下通过采用患者自身的数据进行训练得到,根据个性化的数据训练出个性化的预测模型,充分体现出个性化的血糖管理方式,从而实现个性化的糖尿病健康管理系统。其中,未来一段时间是预先设定的将来的时间段,例如未来的0.5~4h等。所述血糖预测模型输入的血糖数据为时间T到T+t的时序变化的血糖数据,输出的血糖预测值为T+t到T+t+Δt的血糖预测序列 的平均值,其中,Δt的具体取值可以根据患者生活习惯和血糖变化特点等来定,例如可以为3~4h等。本申请的血糖预测模型是在四个模式下分别训练得到的,所述血糖预测模型更稳健,预测效果更准确,血糖管理更加全面;另外,本申请各模式下的血糖预测模型是使用相应模式下患者自身的血糖数据进行训练得到的,实现了个性化的健康管理,且预测结果更加准确,满足了各类糖尿病患者的需求。The blood glucose prediction unit is used for inputting the blood glucose data into a blood glucose prediction model for prediction, and the blood glucose prediction model outputs a blood glucose prediction value in a future period of time, wherein the blood glucose prediction model is performed in the mode by using the patient It is obtained by training its own data, and a personalized prediction model is trained according to the personalized data, which fully reflects the personalized blood sugar management method, so as to realize the personalized diabetes health management system. The future period of time is a preset future period of time, such as 0.5 to 4 hours in the future. The blood glucose data input by the blood glucose prediction model is the blood glucose data of the time series change from time T to T+t, and the output blood glucose prediction value is the average value of the blood glucose prediction sequence from T+t to T+t+Δt, where Δt is the average value of the blood glucose prediction sequence. The specific value can be determined according to the patient's living habits and the characteristics of blood sugar changes, for example, it can be 3 to 4 hours. The blood glucose prediction model of the present application is obtained by training in four modes, the blood glucose prediction model is more robust, the prediction effect is more accurate, and the blood glucose management is more comprehensive; in addition, the blood glucose prediction model in each mode of the present application uses the corresponding mode It is obtained by training the patient's own blood sugar data, realizing personalized health management, and the prediction results are more accurate, meeting the needs of all kinds of diabetic patients.
所述比较单元用于比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值,则发出预警提醒。血糖异常阈值因所处活动模式不同而不同,也可以因人而异,本申请比较单元中是通过阈值设定模块来预先设定血糖异常阈值,另外,患者如需自定义阈值也可以通过阈值设定模块进行修改。所述血糖异常阈值,包括:任何模式下的低血糖阈值G low,休闲模式下的血糖最高阈值G high_relax,饮食模式下血糖最高阈值G high_meal等,且所述饮食模式下的血糖最高阈值高于休闲模式下的血糖最高阈值,即G high_meal>G high_relax。例如,设血糖预测值为y predict,若y predict<G low,发出低血糖预警,其中,G low为任何模式下的低血糖阈值;休闲模式下,若y predict>G high_relax时,发出血糖过高提醒;饮食模式下,若y predict>G high_meal时,发出血糖过高提醒。同理,可以根据患者自身情况通过阈值设定单元预先设置睡眠模式下和运动模式下的血糖最低阈值和血糖最高阈值。本申请个性化的模型和个性化的预警阈值,能够满足糖尿病患者的日常血糖管理,避免发生严重低血糖事件或血糖过高带来的危险。 The comparison unit is used for comparing the predicted blood glucose value with a preset blood glucose abnormality threshold, and if the blood glucose predicted value exceeds the blood glucose abnormality threshold, an early warning reminder is issued. The threshold for abnormal blood glucose varies with different activity modes, and it can also vary from person to person. In the comparison unit of this application, the threshold for abnormal blood glucose is preset through the threshold setting module. In addition, if the patient needs to customize the threshold, it can also pass the threshold Modify the settings module. The abnormal blood glucose threshold includes: the low blood sugar threshold G low in any mode, the highest blood glucose threshold G high_relax in the leisure mode, the highest blood glucose threshold G high_meal in the eating mode, etc., and the highest blood glucose threshold in the eating mode is higher than The highest threshold of blood glucose in leisure mode, ie G high_meal >G high_relax . For example, set the blood sugar prediction value as y predict , if y predict <G low , a low blood sugar warning is issued, where G low is the low blood sugar threshold in any mode; in leisure mode, if y predict > G high_relax , a low blood sugar warning is issued. High reminder; in diet mode, if y predict >G high_meal , a high blood sugar reminder will be sent. Similarly, the lowest blood glucose threshold and the highest blood glucose threshold in the sleep mode and in the exercise mode can be preset through the threshold setting unit according to the patient's own conditions. The personalized model and personalized early warning threshold of the present application can meet the daily blood sugar management of diabetic patients, and avoid the risk of serious hypoglycemia events or hyperglycemia.
下面结合图1和图2对本申请实施例中个性化糖尿病健康管理系统进行详细说明。图1示意性示出了实施例的个性化糖尿病健康管理系统的使用示意图,图2示意性示出了实施例的个性化糖尿病健康管理系统运行流程框架。图1包括:通过网络连接的移动智能终端(智能手机)、蓝牙电子秤、动态血糖仪和智能手环。其中,采用所述移动智能终端可以完成患者基本信息录入和血糖预测模型的调用,同时可以完成系统的功能设定,另外还用于发出警报信息。所述智能手环可以接受警报信息,同时可以记录患者运动模式下的运动数据。所述动态血糖仪用于动态采集患者实时血糖数据并上传至移动智能终端中以进行数据处理、模型构建、预测等操作。所述蓝牙电子秤带有蓝牙功能可以用于收集患者饮食数据并上传至移动智能终端中。患者一天内的血糖会出现较大的波动,比如餐后血糖可能超过10mmol/L,而发生低血糖时,血糖可低至3.9mmol/L,采用本申请个性化糖尿病健康管理系统就可以在不同模式下分别监测血糖,进而通过对应模式下的血糖预测模型进行预测,从而使得血糖警报预测信息更加准确。The personalized diabetes health management system in the embodiment of the present application will be described in detail below with reference to FIG. 1 and FIG. 2 . FIG. 1 schematically shows a schematic diagram of the use of the personalized diabetes health management system of the embodiment, and FIG. 2 schematically shows the operation process framework of the personalized diabetes health management system of the embodiment. Figure 1 includes: a mobile smart terminal (smart phone), a Bluetooth electronic scale, a continuous blood glucose meter and a smart bracelet connected through a network. Wherein, using the mobile intelligent terminal can complete the input of the patient's basic information and the calling of the blood glucose prediction model, and at the same time, the function setting of the system can be completed, and it is also used to send out alarm information. The smart bracelet can receive alarm information, and at the same time, it can record the movement data of the patient in the movement mode. The continuous blood glucose meter is used to dynamically collect real-time blood glucose data of a patient and upload it to a mobile intelligent terminal for data processing, model building, prediction and other operations. The bluetooth electronic scale with bluetooth function can be used to collect the patient's diet data and upload it to the mobile smart terminal. The blood sugar of the patient will fluctuate greatly within a day. For example, the blood sugar after meals may exceed 10mmol/L, and when hypoglycemia occurs, the blood sugar can be as low as 3.9mmol/L. The personalized diabetes health management system of this application can be used in different The blood sugar is monitored separately in the mode, and then predicted by the blood sugar prediction model in the corresponding mode, so that the blood sugar alarm prediction information is more accurate.
在一可选实施例中,所述系统还可以包括录入调用单元,用于录入患者基本信息,以及根据患者基本信息调用采用所述患者自身的血糖数据进行训练得到的血糖预测模型。其中,基本信息可以包括:患者姓名、性别、出生日期、身体质量指数BMI等。如图2所示,患者通过移动智能终端登录个性化糖尿病健康管理系统,初次使用时需要录入基本信息;然后根据患者每天的活动或所介于的时间段选择对应模式进行血糖预测模型训练,或者直接进入健康管理状态通过血糖预测模型进行血糖预测,最后进行比对后通过移动智能终端 或者智能手环等作出警报提醒。本申请通过根据患者基本信息调用属于患者个人的血糖预测模型(即采用该患者自身数据训练得到的模型),进一步确保了血糖预测模型与患者一一对应,使得后续的血糖预测结果更加个性化,满足了不同患者的需求。In an optional embodiment, the system may further include an input and call unit for inputting basic patient information, and calling a blood glucose prediction model trained by using the patient's own blood glucose data according to the patient's basic information. The basic information may include: patient name, gender, date of birth, body mass index BMI, and the like. As shown in Figure 2, the patient logs into the personalized diabetes health management system through a mobile smart terminal, and basic information needs to be entered when using it for the first time; then select the corresponding mode to train the blood glucose prediction model according to the patient's daily activities or the time period in between, or Directly enter the health management state to predict blood sugar through the blood sugar prediction model, and finally make an alarm reminder through mobile smart terminals or smart bracelets after the comparison. The present application further ensures that the blood glucose prediction model corresponds to the patient one-to-one by calling the blood glucose prediction model belonging to the individual patient (that is, the model obtained by using the patient's own data) according to the basic information of the patient, so that the subsequent blood glucose prediction results are more personalized. meet the needs of different patients.
本申请中,所述个性化糖尿病健康管理系统,还包括:模型构建单元,用于采用LSTM算法构建不同模式下的血糖预测模型。其中,在模型构建过程中,每个模式下模型的构建过程相同,不同的是构建模型的参数和模型的数据(数据因是在不同模数下采集的所以不同)。为了提供个性化的管理方案,本申请提出使用患者自身的血糖数据进行血糖预测模型的训练,并且在不同的模式下使用不同的预测模型,分别训练模型有利于建立更精确的预测模型,同时也增加了个性化,使得血糖预测不仅在个人上表现不同,还在不同的模式下表现不同。LSTM(longshort-termmemory)非常适合用于时序序列的预测,即能够处理序列变化的数据。图4示意性地示出了LSTM的框架结构。如图4所示,其由一个忘记门z f,一个输入门z i,一个输出门z o控制,对上一个节点传进来的输入进行选择性忘记,将这个阶段的输入有选择性地进行记忆,将这两部分相加,得到传输给下一个状态的c t,输出阶段将决定哪些信息将会被当成当前状态的输出,由z o控制,得到h t。最后的输出y t由h t经过变换后得到。其中,c t、h t、y t的表达式分别为:c t=z f⊙c t-1+z i⊙z;y t=σ(W′h t);h t=z o⊙tanh(c t)。图5示意性的示出了LSTM的层结构,如图5所示,包括输入层(X 1、X 2……X t),LSTM层(A1、A2……At;h1、h2……ht)、以及输出层(y 1、y 2、……y t);输入为处理好的时序血糖数据,输出为下一时段的血糖数据。 In this application, the personalized diabetes health management system further includes: a model building unit for building blood glucose prediction models in different modes by using the LSTM algorithm. Among them, in the model building process, the model building process in each mode is the same, and the difference is the parameters for building the model and the data of the model (the data are different because they are collected under different moduli). In order to provide a personalized management plan, the present application proposes to use the patient's own blood glucose data to train the blood glucose prediction model, and use different prediction models in different modes. Added personalization so that blood glucose predictions not only behave differently on an individual basis, but also in different modes. LSTM (longshort-term memory) is very suitable for the prediction of time series series, that is, data that can process changes in the sequence. Figure 4 schematically shows the framework structure of LSTM. As shown in Figure 4, it is controlled by a forget gate z f , an input gate z i , and an output gate zo , selectively forget the input from the previous node, and selectively forget the input of this stage. Memory, add these two parts to get ct that is transmitted to the next state, the output stage will decide which information will be regarded as the output of the current state, controlled by zo, get h t . The final output y t is obtained by transforming h t . Among them, the expressions of c t , h t , and y t are respectively: c t =z f ⊙c t-1 +z i ⊙z; y t =σ(W′h t ); h t =z o ⊙tanh (c t ). Fig. 5 schematically shows the layer structure of LSTM, as shown in Fig. 5 , including input layer (X1, X2... Xt ), LSTM layer (A1, A2...At; h1, h2...ht ), and the output layer (y 1 , y 2 , ... y t ); the input is the processed time series blood glucose data, and the output is the blood glucose data of the next period.
在一可选实施例中,所述模型构建单元中,可以包括:数据处理模块、模型训练模块、以及模型验证模块等。In an optional embodiment, the model building unit may include: a data processing module, a model training module, a model verification module, and the like.
其中,所述数据处理模块用于采用滑动窗口的方式对血糖数据进行处理;其中,所述血糖数据为通过所述数据采集单元采集到的患者在各模式下自身的时序变化的血糖数据。图3示意性示出了滑动窗口的结构,采用滑动窗口的方式,这样可以让训练数据增多。滑动窗口T的长度表示每个时间步长s的长度,也就是输入X的长度。进一步地,所述数据处理模块还用于将血糖数据划分为两部分,一部分用于模型训练模块对血糖预测模型进行训练,另一部分用于模型验证模块对血糖预测模型进行验证。例如,可以将血糖数据分为80%用于训练,20%用于验证。Wherein, the data processing module is used to process the blood sugar data in a sliding window manner; wherein, the blood sugar data is the blood sugar data of the patient's own time series changes in each mode collected by the data acquisition unit. FIG. 3 schematically shows the structure of the sliding window, and the sliding window method is adopted, which can increase the training data. The length of the sliding window T represents the length of each time step s, which is the length of the input X. Further, the data processing module is also used for dividing the blood glucose data into two parts, one part is used for the model training module to train the blood glucose prediction model, and the other part is used for the model verification module to verify the blood glucose prediction model. For example, blood glucose data can be split into 80% for training and 20% for validation.
所述模型训练模块采用处理后的患者自身血糖数据进行血糖预测模型的训练;其中,不同模式下的血糖数据训练得到不同的血糖预测模型。也就是说,为了训练个性化的血糖预测模型,患者需要提前使用一段时间例如一个月,采用数据采集单元来收集患者不同模式下时序变化的血糖数据,以进行模型训练,从而充分体现出个性化的血糖管理方式;同理,在该使用过程中,不同模式下的血糖预测模型的训练采用的是该患者在对应模式下的血糖数据。对于模式,本申请可以根据患者自身活动切换模式,也可以根据时间来切换模式。也就是说,所处模式可以根据血糖数据采集时患者所进行的活动来确定,例如,患者可以根据当前所进行的活动,进行模式切换,将该模式与在该模式下采集的血糖数据一并 上传,以便后续对血糖数据进行标签标注工作,从而提高模型预测准确度;当然,所处模式也可以根据血糖数据采集时所处的时间段来确定,例如,可以将根据时间段来确定血糖数据所处模式设置为默认情况,即用户没有进行模式选择切换时,系统根据时间进行模式切换,例如如00:00:00-06:00:00属于睡眠模式。The model training module uses the processed blood glucose data of the patient to train the blood glucose prediction model; wherein, different blood glucose prediction models are obtained by training the blood glucose data in different modes. That is to say, in order to train a personalized blood glucose prediction model, the patient needs to use it for a period of time in advance, such as a month, and use the data acquisition unit to collect the blood glucose data of the patient's blood sugar changes in different modes for model training, so as to fully reflect the personalized In the same way, during the use process, the training of the blood glucose prediction models in different modes uses the blood glucose data of the patient in the corresponding mode. As for the mode, the present application can switch the mode according to the patient's own activities, and can also switch the mode according to the time. That is to say, the mode can be determined according to the activity performed by the patient when the blood glucose data is collected. For example, the patient can switch the mode according to the current activity, and combine the mode with the blood glucose data collected in this mode. Upload, so as to label the blood sugar data later, so as to improve the prediction accuracy of the model; of course, the mode can also be determined according to the time period when the blood sugar data is collected. For example, the blood sugar data can be determined according to the time period. The mode is set to the default state, that is, when the user does not switch the mode selection, the system switches the mode according to the time, for example, 00:00:00-06:00:00 belongs to the sleep mode.
所述模型验证模块采用处理后的患者自身血糖数据进行血糖预测模型的验证,若预测值与真实值的误差在阈值内,则血糖预测模型构建完成。即在20%的数据上测试下一时段血糖数据真实值与预测值的误差,具体地,根据20%的血糖数据进行验证,若误差在阈值(所允许的范围)内,模型验证通过,便可得到相应模式下训练好的血糖预测模型,若误差不在阈值内,需要继续训练并验证血糖预测模型,直至模型验证通过得到训练好的模型。The model verification module uses the processed blood glucose data of the patient to verify the blood glucose prediction model. If the error between the predicted value and the actual value is within the threshold, the blood glucose prediction model is constructed. That is, the error between the actual value and the predicted value of the blood glucose data in the next period is tested on 20% of the data. Specifically, the verification is carried out according to 20% of the blood glucose data. If the error is within the threshold (allowed range), the model verification is passed, then The blood glucose prediction model trained in the corresponding mode can be obtained. If the error is not within the threshold, it is necessary to continue training and verify the blood glucose prediction model until the model is verified and the trained model is obtained.
在一可选实施例中,所述数据采集单元中,还包括:数据标注模块。模型构建时,需要在数据收集过程中对数据进行标签标注,即需要有所处模式标签和异常发生标签,这样才能进行后续的模型训练。本申请采用所述数据标注模块用于对血糖数据的所处的模式进行标注得到所处模式标签,同时用于对血糖数据的异常情况进行标注得到异常发生标签,并将所处模式标签和异常发生标签上传至模型构建单元中,以对血糖预测模型进行构建和训练等步骤。进一步地,可以根据血糖数据采集时患者所进行的活动,或根据血糖数据采集时所处的时间段,对血糖数据的所处的模式进行标注。另外,若用户没有选择所处模式时,便可默认采用时间段来确定该血糖数据的所处模式。其中,所处模式标签包括运动模式标签、睡眠模式标签、饮食模式标签、休闲模式标签,例如,患者运动时采集到的血糖数据标注为运动模式标签,将00:00:00-06:00:00时间段获取的血糖数据标注为睡眠模式标签。所述异常发生标签可以包括:低血糖标签、血糖过高标签等,例如,当发生低血糖或高血糖时,用户可以通过智能设备返回异常标签(如点击智能手环上的异常上报按钮),这样血糖数据就有了所处模式标签和异常发生标签。In an optional embodiment, the data collection unit further includes: a data labeling module. When the model is built, the data needs to be labeled during the data collection process, that is, the mode label and the abnormal occurrence label are required, so that the subsequent model training can be carried out. In this application, the data labeling module is used to label the mode in which the blood glucose data is located to obtain the mode label, and at the same time, it is used to label the abnormal situation of the blood glucose data to obtain the abnormality occurrence label, and the mode label and the abnormality label are obtained. The occurrence label is uploaded to the model building unit to construct and train the blood glucose prediction model. Further, the mode in which the blood glucose data is located may be marked according to the activities performed by the patient when the blood glucose data is collected, or according to the time period in which the blood glucose data is collected. In addition, if the user does not select the mode, the time period may be used by default to determine the mode of the blood glucose data. Among them, the mode label includes exercise mode label, sleep mode label, diet mode label, and leisure mode label. For example, the blood glucose data collected when the patient is exercising is labeled as the exercise mode label, and 00:00:00-06:00: The blood glucose data obtained in the 00 period is marked as the sleep mode label. The abnormality label may include: low blood sugar label, high blood sugar label, etc. For example, when low blood sugar or high blood sugar occurs, the user can return to the abnormal label through the smart device (for example, click the abnormal report button on the smart bracelet), In this way, the blood glucose data has the mode label and the abnormal occurrence label.
在一可选实施例中,所述个性化糖尿病健康管理系统,还可以包括:热量提醒单元,用于获取饮食模式下的食物类型,计算食物热量,并判断食物热量是否超过预设热量阈值,若超过,则发出饮食不合理提醒。具体地,患者就餐时,可以选择食物类型包括主食、蔬菜、水果、肉等,采用蓝牙电子秤称取重量后,计算食物热量,以提示患者饮食是否合理。In an optional embodiment, the personalized diabetes health management system may further include: a calorie reminder unit, configured to acquire the type of food in the eating mode, calculate the calorie of the food, and determine whether the calorie of the food exceeds a preset calorie threshold, If it exceeds, a reminder of unreasonable diet will be issued. Specifically, when the patient eats, he or she can choose the type of food, including staple food, vegetables, fruit, meat, etc., after taking the weight with a Bluetooth electronic scale, calculate the calories of the food to remind the patient whether the diet is reasonable.
在另一可选实施例中,所述热量提醒单元,用于判断热量差值是否超过预设热量阈值,若超过,则发出饮食不合理提醒。其中,热量差值是指饮食模式下的食物热量和运动模式下所消耗的热量的差值。In another optional embodiment, the calorie reminder unit is configured to determine whether the calorie difference exceeds a preset calorie threshold, and if it exceeds, a reminder of unreasonable diet is issued. The calorie difference refers to the difference between the food calorie in the eating mode and the calorie consumed in the exercise mode.
图6示意性示出了本申请实施例个性化糖尿病健康管理系统的结构,如图6所示,本申请个性化糖尿病健康管理系统,在模型构建时:通过录入调用单元录入患者信息;通过数据采集单元采集同一患者在不同模式下的血糖数据,采用数据标注模块进行标签标注;然后输入模型构建单元,采用数据处理模块对数据进行处理,并将处理后数据输入到模型训练模块和模型验证模块进行模型训练和验证,最终得到训练好的血糖预测模型。在模型应用时:通过录入调用单元调用与患者匹配的模型,通过数据采集单元采集该患者在某模 式下的血糖数据,将所述血糖数据输入血糖预测单元中通过血糖预测模型(与患者和模式均对应的模型)进行血糖预测,输出未来一段时间内的血糖预测值,然后通过比较单元将其与阈值比较后作出预警提醒。FIG. 6 schematically shows the structure of the personalized diabetes health management system according to the embodiment of the present application. As shown in FIG. 6 , in the personalized diabetes health management system of the present application, when the model is constructed: the patient information is entered through the entry calling unit; The acquisition unit collects the blood glucose data of the same patient in different modes, and uses the data labeling module for labeling; and then enters the model building unit, uses the data processing module to process the data, and inputs the processed data to the model training module and model verification module. Carry out model training and verification, and finally obtain a trained blood glucose prediction model. When the model is applied: call the model matching the patient through the input calling unit, collect the blood glucose data of the patient in a certain mode through the data acquisition unit, input the blood glucose data into the blood glucose prediction unit, and pass the blood glucose prediction model (with the patient and the mode) model) to predict blood sugar, output the predicted value of blood sugar in a period of time in the future, and then compare it with the threshold value through the comparison unit to make an early warning reminder.
本申请通过将采集到的某模式下的血糖数据输入到采用该模式下患者自身的血糖数据训练好的血糖预测模型中进行预测后,可输出未来时间段内的血糖预测值并根据其与阈值的比较结果来发出预警信号,使得血糖管理更加全面,血糖预警结果更加精确,实现了个性化的血糖管理,可以满足各类糖尿病患者的需求。In the present application, after inputting the collected blood glucose data in a certain mode into the blood glucose prediction model trained by the patient's own blood glucose data in this mode for prediction, the blood glucose prediction value in the future time period can be output and based on the difference between the blood glucose prediction value and the threshold value The comparison results are used to issue early warning signals, which makes blood sugar management more comprehensive, and the blood sugar early warning results are more accurate. Personalized blood sugar management can be realized, which can meet the needs of all kinds of diabetic patients.
图7是本申请实现管理程序的电子设备的结构示意图。如图7所示,所述电子设备1可以包括处理器10、存储器11和总线,还可以包括存储在所述存储器11中并可在所述处理器10上运行的计算机程序,如管理程序12。FIG. 7 is a schematic structural diagram of an electronic device implementing a management program in the present application. As shown in FIG. 7 , the electronic device 1 may include a processor 10, a memory 11 and a bus, and may also include a computer program stored in the memory 11 and executed on the processor 10, such as a management program 12 .
其中,所述存储器11至少包括一种类型的可读存储介质,所述可读存储介质包括闪存、移动硬盘、多媒体卡、卡型存储器(例如:SD或DX存储器等)、磁性存储器、磁盘、光盘等。所述存储器11在一些实施例中可以是电子设备1的内部存储单元,例如该电子设备1的移动硬盘。所述存储器11在另一些实施例中也可以是电子设备1的外部存储设备,例如电子设备1上配备的插接式移动硬盘、智能存储卡(Smart Media Card,SMC)、安全数字(Secure Digital,SD)卡、闪存卡(Flash Card)等。进一步地,所述存储器11还可以既包括电子设备1的内部存储单元也包括外部存储设备。所述存储器11不仅可以用于存储安装于电子设备1的应用软件及各类数据,例如管理程序的代码等,还可以用于暂时地存储已经输出或者将要输出的数据。Wherein, the memory 11 includes at least one type of readable storage medium, and the readable storage medium includes flash memory, mobile hard disk, multimedia card, card-type memory (for example: SD or DX memory, etc.), magnetic memory, magnetic disk, CD etc. The memory 11 may be an internal storage unit of the electronic device 1 in some embodiments, such as a mobile hard disk of the electronic device 1 . In other embodiments, the memory 11 may also be an external storage device of the electronic device 1, such as a pluggable mobile hard disk, a smart memory card (Smart Media Card, SMC), a secure digital (Secure Digital) equipped on the electronic device 1. , SD) card, flash memory card (Flash Card), etc. Further, the memory 11 may also include both an internal storage unit of the electronic device 1 and an external storage device. The memory 11 can not only be used to store application software installed in the electronic device 1 and various types of data, such as codes of management programs, etc., but also can be used to temporarily store data that has been output or will be output.
所述处理器10在一些实施例中可以由集成电路组成,例如可以由单个封装的集成电路所组成,也可以是由多个相同功能或不同功能封装的集成电路所组成,包括一个或者多个中央处理器(Central Processing unit,CPU)、微处理器、数字处理芯片、图形处理器及各种控制芯片的组合等。所述处理器10是所述电子设备的控制核心(Control Unit),利用各种接口和线路连接整个电子设备的各个部件,通过运行或执行存储在所述存储器11内的程序或者模块(例如管理程序等),以及调用存储在所述存储器11内的数据,以执行电子设备1的各种功能和处理数据。In some embodiments, the processor 10 may be composed of integrated circuits, for example, may be composed of a single packaged integrated circuit, or may be composed of multiple integrated circuits packaged with the same function or different functions, including one or more integrated circuits. Central Processing Unit (CPU), microprocessor, digital processing chip, graphics processor and combination of various control chips, etc. The processor 10 is the control core (Control Unit) of the electronic device, and uses various interfaces and lines to connect the various components of the entire electronic device, by running or executing programs or modules (such as management and control) stored in the memory 11. programs, etc.), and call data stored in the memory 11 to execute various functions of the electronic device 1 and process data.
所述总线可以是外设部件互连标准(peripheral component interconnect,简称PCI)总线或扩展工业标准结构(extended industry standard architecture,简称EISA)总线等。该总线可以分为地址总线、数据总线、控制总线等。所述总线被设置为实现所述存储器11以及至少一个处理器10等之间的连接通信。The bus may be a peripheral component interconnect (PCI for short) bus or an extended industry standard architecture (Extended industry standard architecture, EISA for short) bus or the like. The bus can be divided into address bus, data bus, control bus and so on. The bus is configured to implement connection communication between the memory 11 and at least one processor 10 and the like.
图7仅示出了具有部件的电子设备,本领域技术人员可以理解的是,其并不构成对所述电子设备1的限定,可以包括比图示更少或者更多的部件,或者组合某些部件,或者不同的部件布置。FIG. 7 only shows an electronic device with components, and those skilled in the art can understand that it does not constitute a limitation on the electronic device 1, and may include fewer or more components than the one shown, or a combination of certain components may be included. some components, or a different arrangement of components.
例如,尽管未示出,所述电子设备1还可以包括给各个部件供电的电源(比如电池),优选地,电源可以通过电源管理装置与所述至少一个处理器10逻辑相连,从而通过电源 管理装置实现充电管理、放电管理、以及功耗管理等功能。电源还可以包括一个或一个以上的直流或交流电源、再充电装置、电源故障检测电路、电源转换器或者逆变器、电源状态指示器等任意组件。所述电子设备1还可以包括多种传感器、蓝牙模块、Wi-Fi模块等,在此不再赘述。For example, although not shown, the electronic device 1 may also include a power supply (such as a battery) for powering the various components, preferably, the power supply may be logically connected to the at least one processor 10 through a power management device, so that the power management The device implements functions such as charge management, discharge management, and power consumption management. The power source may also include one or more DC or AC power sources, recharging devices, power failure detection circuits, power converters or inverters, power status indicators, and any other components. The electronic device 1 may further include various sensors, Bluetooth modules, Wi-Fi modules, etc., which will not be repeated here.
进一步地,所述电子设备1还可以包括网络接口,可选地,所述网络接口可以包括有线接口和/或无线接口(如WI-FI接口、蓝牙接口等),通常用于在该电子设备1与其他电子设备之间建立通信连接。Further, the electronic device 1 may also include a network interface, optionally, the network interface may include a wired interface and/or a wireless interface (such as a WI-FI interface, a Bluetooth interface, etc.), which is usually used in the electronic device 1 Establish a communication connection with other electronic devices.
可选地,该电子设备1还可以包括用户接口,用户接口可以是显示器(Display)、输入单元(比如键盘(Keyboard)),可选地,用户接口还可以是标准的有线接口、无线接口。可选地,在一些实施例中,显示器可以是LED显示器、液晶显示器、触控式液晶显示器以及OLED(Organic Light-Emitting Diode,有机发光二极管)触摸器等。其中,显示器也可以适当的称为显示屏或显示单元,用于显示在电子设备1中处理的信息以及用于显示可视化的用户界面。Optionally, the electronic device 1 may further include a user interface, and the user interface may be a display (Display), an input unit (eg, a keyboard (Keyboard)), optionally, the user interface may also be a standard wired interface or a wireless interface. Optionally, in some embodiments, the display may be an LED display, a liquid crystal display, a touch-sensitive liquid crystal display, an OLED (Organic Light-Emitting Diode, organic light-emitting diode) touch device, and the like. The display may also be appropriately called a display screen or a display unit, which is used for displaying information processed in the electronic device 1 and for displaying a visualized user interface.
应该了解,所述实施例仅为说明之用,在专利申请范围上并不受此结构的限制。It should be understood that the embodiments are only used for illustration, and are not limited by this structure in the scope of the patent application.
所述电子设备1中的所述存储器11存储的管理程序12是多个指令的组合,在所述处理器10中运行时,可以实现各单元和/或模块的功能,例如:用于获取患者所处的模式并采集患者在所述模式下时序变化的血糖数据的数据采集单元;用于将所述血糖数据输入到血糖预测模型中进行预测,血糖预测模型输出未来一段时间内的血糖预测值的血糖预测单元;用于比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值则发出预警提醒的比较单元等。The management program 12 stored in the memory 11 in the electronic device 1 is a combination of multiple instructions, and when running in the processor 10, the functions of each unit and/or module can be implemented, for example: for obtaining a patient A data acquisition unit that collects the blood glucose data of the patient in the mode and the time series changes in the mode; used to input the blood glucose data into the blood glucose prediction model for prediction, and the blood glucose prediction model outputs the blood glucose prediction value for a period of time in the future The blood glucose prediction unit; a comparison unit for comparing the blood glucose prediction value with a preset blood glucose abnormality threshold, and issuing an early warning if the blood glucose prediction value exceeds the blood glucose abnormality threshold.
具体地,所述处理器10对上述指令的具体实现方法可参考图6对应实施例中相关描述,在此不赘述。Specifically, for the specific implementation method of the above-mentioned instruction by the processor 10, reference may be made to the relevant description in the corresponding embodiment of FIG. 6, and details are not described herein.
进一步地,所述电子设备1集成的模块/单元如果以软件功能单元的形式实现并作为独立的产品销售或使用时,可以存储在一个计算机可读取存储介质中,所述计算机可读存储介质可以是非易失性,也可以是易失性。其中,所述计算机可读存储介质可以是任何包含或存储程序或指令的有形介质,其上存储有可以被执行的计算机程序,该计算机程序被处理器执行时,通过存储的程序指令相关的硬件实现本申请个性化糖尿病健康管理系统各单元/模块的功能。例如,通过存储的程序指令相关硬件来实现获取患者所处的模式并采集患者在所述模式下时序变化的血糖数据,将所述血糖数据输入到血糖预测模型中进行预测,血糖预测模型输出未来一段时间内的血糖预测值,比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值则发出预警提醒等功能。所述计算机可读介质,例如可以包括:能够携带所述计算机程序代码的任何实体或装置、记录介质、U盘、移动硬盘、磁碟、光盘、计算机存储器、只读存储器(ROM,Read-Only Memory)。Further, if the modules/units integrated by the electronic device 1 are implemented in the form of software functional units and sold or used as independent products, they can be stored in a computer-readable storage medium, and the computer-readable storage medium Can be non-volatile or volatile. Wherein, the computer-readable storage medium can be any tangible medium that contains or stores programs or instructions, on which a computer program that can be executed is stored. When the computer program is executed by the processor, the stored program instructs the relevant hardware through the stored program. The functions of each unit/module of the personalized diabetes health management system of the present application are realized. For example, the stored program instructs the relevant hardware to obtain the mode the patient is in and collect the blood glucose data of the patient's time-series changes in the mode, input the blood glucose data into the blood glucose prediction model for prediction, and the blood glucose prediction model outputs the future The predicted blood glucose value within a period of time, compares the predicted blood glucose value with a preset blood glucose abnormality threshold, and issues a warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold. The computer-readable medium, for example, may include: any entity or device capable of carrying the computer program code, recording medium, U disk, removable hard disk, magnetic disk, optical disk, computer memory, read-only memory (ROM, Read-Only Memory) Memory).
在本申请所提供的几个实施例中,应该理解到,所揭露的设备和装置,可以通过其它的方式实现。例如,以上所描述的装置实施例仅仅是示意性的,例如,所述模块的划分, 仅仅为一种逻辑功能划分,实际实现时可以有另外的划分方式。In the several embodiments provided in this application, it should be understood that the disclosed devices and apparatuses may be implemented in other manners. For example, the apparatus embodiments described above are only illustrative. For example, the division of the modules is only a logical function division, and there may be other division manners in actual implementation.
所述作为分离部件说明的模块可以是或者也可以不是物理上分开的,作为模块显示的部件可以是或者也可以不是物理单元,即可以位于一个地方,或者也可以分布到多个网络单元上。可以根据实际的需要选择其中的部分或者全部模块来实现本实施例方案的目的。The modules described as separate components may or may not be physically separated, and components shown as modules may or may not be physical units, that is, may be located in one place, or may be distributed to multiple network units. Some or all of the modules may be selected according to actual needs to achieve the purpose of the solution in this embodiment.
另外,在本申请各个实施例中的各功能模块可以集成在一个处理单元中,也可以是各个单元单独物理存在,也可以两个或两个以上单元集成在一个单元中。上述集成的单元既可以采用硬件的形式实现,也可以采用硬件加软件功能模块的形式实现。In addition, each functional module in each embodiment of the present application may be integrated into one processing unit, or each unit may exist physically alone, or two or more units may be integrated into one unit. The above-mentioned integrated units can be implemented in the form of hardware, or can be implemented in the form of hardware plus software function modules.
对于本领域技术人员而言,显然本申请不限于上述示范性实施例的细节,而且在不背离本申请的精神或基本特征的情况下,能够以其他的具体形式实现本申请。It will be apparent to those skilled in the art that the present application is not limited to the details of the above-described exemplary embodiments, but that the present application can be implemented in other specific forms without departing from the spirit or essential characteristics of the present application.
因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本申请的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化涵括在本申请内。不应将权利要求中的任何附关联图标记视为限制所涉及的权利要求。Accordingly, the embodiments are to be regarded in all respects as illustrative and not restrictive, and the scope of the application is to be defined by the appended claims rather than the foregoing description, which is therefore intended to fall within the scope of the claims. All changes within the meaning and scope of the equivalents of , are included in this application. Any reference signs in the claims shall not be construed as limiting the involved claim.
此外,显然“包括”一词不排除其他单元或步骤,单数不排除复数。系统权利要求中陈述的多个单元或装置也可以由一个单元或装置通过软件或者硬件来实现。第二等词语用来表示名称,而并不表示任何特定的顺序。Furthermore, it is clear that the word "comprising" does not exclude other units or steps and the singular does not exclude the plural. Several units or means recited in the system claims can also be realized by one unit or means by means of software or hardware. Second-class terms are used to denote names and do not denote any particular order.
最后应说明的是,以上实施例仅用以说明本申请的技术方案而非限制,尽管参照较佳实施例对本申请进行了详细说明,本领域的普通技术人员应当理解,可以对本申请的技术方案进行修改或等同替换,而不脱离本申请技术方案的精神和范围。Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application rather than limitations. Although the present application has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present application can be Modifications or equivalent substitutions can be made without departing from the spirit and scope of the technical solutions of the present application.

Claims (20)

  1. 一种个性化糖尿病健康管理系统,其中,所述系统包括:A personalized diabetes health management system, wherein the system includes:
    数据采集单元,用于获取患者所处的模式,并采集患者在所述模式下时序变化的血糖数据,其中,所述模式包括:睡眠模式、饮食模式、运动模式和休闲模式;a data acquisition unit, configured to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient with time series changes in the mode, wherein the mode includes: a sleep mode, a diet mode, an exercise mode and a leisure mode;
    血糖预测单元,用于将所述血糖数据输入到血糖预测模型中进行预测,并通过血糖预测模型输出未来一段时间内的血糖预测值,其中,所述血糖预测模型是在所述模式下通过采用患者自身的数据进行训练得到;A blood sugar prediction unit, configured to input the blood sugar data into a blood sugar prediction model for prediction, and output a blood sugar prediction value in a future period of time through the blood sugar prediction model, wherein the blood sugar prediction model is performed in the mode by adopting The patient's own data is trained;
    比较单元,用于比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值,则发出预警提醒。A comparison unit, configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
  2. 根据权利要求1所述的个性化糖尿病健康管理系统,其中,所述系统还包括:模型构建单元,用于采用LSTM算法构建不同模式下的血糖预测模型。The personalized diabetes health management system according to claim 1, wherein the system further comprises: a model building unit for building blood glucose prediction models in different modes by using the LSTM algorithm.
  3. 根据权利要求2所述的个性化糖尿病健康管理系统,其中,所述模型构建单元中,包括:The personalized diabetes health management system according to claim 2, wherein the model building unit includes:
    数据处理模块,用于采用滑动窗口的方式对血糖数据进行处理,其中,所述血糖数据为通过所述数据采集单元采集到的患者在各模式下自身的时序变化的血糖数据;a data processing module for processing blood glucose data in a sliding window manner, wherein the blood glucose data is the blood glucose data of the patient's own time-series changes in each mode collected by the data acquisition unit;
    模型训练模块,采用处理后的患者自身血糖数据进行血糖预测模型的训练,其中,不同模式下的血糖数据训练得到不同的血糖预测模型;The model training module uses the processed blood glucose data of the patient to train the blood glucose prediction model, wherein different blood glucose prediction models are obtained by training the blood glucose data in different modes;
    模型验证模块,采用处理后的患者自身血糖数据进行血糖预测模型的验证,若预测值与真实值的误差在阈值内,则血糖预测模型构建完成。The model verification module uses the processed patient's own blood glucose data to verify the blood glucose prediction model. If the error between the predicted value and the actual value is within the threshold, the blood glucose prediction model is constructed.
  4. 根据权利要求3所述的个性化糖尿病健康管理系统,其中,所述数据处理模块,还用于将血糖数据划分为两部分,一部分用于模型训练模块对血糖预测模型进行训练,另一部分用于模型验证模块对血糖预测模型进行验证。The personalized diabetes health management system according to claim 3, wherein the data processing module is further configured to divide the blood glucose data into two parts, one part is used for the model training module to train the blood glucose prediction model, and the other part is used for training the blood glucose prediction model. The model validation module validates the blood glucose prediction model.
  5. 根据权利要求1所述的个性化糖尿病健康管理系统,其中,所述数据采集单元中,还包括:The personalized diabetes health management system according to claim 1, wherein the data acquisition unit further comprises:
    数据标注模块,用于对血糖数据的所处的模式进行标注得到所处模式标签,以及用于血糖数据的异常情况进行标注得到异常发生标签,并将所处模式标签和异常发生标签上传至模型构建单元,以构建血糖预测模型;其中,根据血糖数据采集时患者所进行的活动,或血糖数据采集时所处的时间段,对血糖数据的所处的模式进行标注。The data labeling module is used to label the mode of the blood glucose data to obtain the mode label, and to label the abnormal situation of the blood glucose data to obtain the abnormal occurrence label, and upload the mode label and the abnormal occurrence label to the model A construction unit is used to construct a blood glucose prediction model; wherein, according to the activities performed by the patient when the blood glucose data is collected, or the time period in which the blood glucose data is collected, the mode of the blood glucose data is marked.
  6. 根据权利要求1所述的个性化糖尿病健康管理系统,其中,所述系统还包括:录入调用单元,用于录入患者基本信息,以及根据患者基本信息调用采用所述患者自身的血糖数据进行训练得到的血糖预测模型。The personalized diabetes health management system according to claim 1, wherein the system further comprises: an input and call unit for inputting the basic information of the patient, and calling and training the blood glucose data of the patient according to the basic information of the patient. blood glucose prediction model.
  7. 根据权利要求1所述的个性化糖尿病健康管理系统,其中,所述血糖预测模型的输入的血糖数据为时间T到T+t的时序变化的血糖数据,输出的血糖预测值为T+t到T+t+Δt的血糖预测序列的平均值。The personalized diabetes health management system according to claim 1, wherein the input blood sugar data of the blood sugar prediction model is blood sugar data of time series change from time T to T+t, and the output blood sugar prediction value is from T+t to T+t. The mean of the blood glucose prediction series for T+t+Δt.
  8. 根据权利要求1所述的个性化糖尿病健康管理系统,其中,所述血糖异常阈值,包括:任何模式下的低血糖预警阈值、休闲模式下的血糖最高阈值、和饮食模式下的血糖最高阈值,其中,所述饮食模式下的血糖最高阈值高于休闲模式下的血糖最高阈值。The personalized diabetes health management system according to claim 1, wherein the abnormal blood sugar threshold includes: a low blood sugar warning threshold in any mode, a maximum blood sugar threshold in a leisure mode, and a maximum blood sugar threshold in a diet mode, Wherein, the highest blood glucose threshold in the eating mode is higher than the highest blood glucose threshold in the leisure mode.
  9. 一种电子设备,其中,所述电子设备包括:An electronic device, wherein the electronic device comprises:
    至少一个处理器;以及,at least one processor; and,
    与所述至少一个处理器通信连接的存储器;其中,a memory communicatively coupled to the at least one processor; wherein,
    所述存储器存储有可被所述至少一个处理器执行的指令,所述指令被所述至少一个处理器执行,以使所述至少一个处理器能够执行个性化糖尿病健康管理系统中的如下各单元的功能:The memory stores instructions executable by the at least one processor, the instructions being executed by the at least one processor to enable the at least one processor to execute the following elements in the personalized diabetes health management system function:
    数据采集单元,用于获取患者所处的模式,并采集患者在所述模式下时序变化的血糖数据,其中,所述模式包括:睡眠模式、饮食模式、运动模式和休闲模式;a data acquisition unit, configured to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient with time series changes in the mode, wherein the mode includes: a sleep mode, a diet mode, an exercise mode and a leisure mode;
    血糖预测单元,用于将所述血糖数据输入到血糖预测模型中进行预测,并通过血糖预测模型输出未来一段时间内的血糖预测值,其中,所述血糖预测模型是在所述模式下通过采用患者自身的数据进行训练得到;A blood sugar prediction unit, configured to input the blood sugar data into a blood sugar prediction model for prediction, and output a blood sugar prediction value in a future period of time through the blood sugar prediction model, wherein the blood sugar prediction model is performed in the mode by adopting The patient's own data is trained;
    比较单元,用于比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值,则发出预警提醒。A comparison unit, configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
  10. 根据权利要求9所述的电子设备,其中,至少一个处理器还能够执行个性化糖尿病健康管理系统中如下单元的功能:The electronic device of claim 9, wherein the at least one processor is further capable of performing the functions of the following units in the personalized diabetes health management system:
    模型构建单元,用于采用LSTM算法构建不同模式下的血糖预测模型。The model building unit is used to build blood glucose prediction models in different modes by using the LSTM algorithm.
  11. 根据权利要求10所述的电子设备,其中,执行所述模型构建单元的功能时,还执行如下各模块的功能:The electronic device according to claim 10, wherein, when executing the function of the model building unit, it also executes the functions of the following modules:
    数据处理模块,用于采用滑动窗口的方式对血糖数据进行处理,其中,所述血糖数据为通过所述数据采集单元采集到的患者在各模式下自身的时序变化的血糖数据;a data processing module for processing blood glucose data in a sliding window manner, wherein the blood glucose data is the blood glucose data of the patient's own time-series changes in each mode collected by the data acquisition unit;
    模型训练模块,采用处理后的患者自身血糖数据进行血糖预测模型的训练,其中,不同模式下的血糖数据训练得到不同的血糖预测模型;The model training module uses the processed blood glucose data of the patient to train the blood glucose prediction model, wherein different blood glucose prediction models are obtained by training the blood glucose data in different modes;
    模型验证模块,采用处理后的患者自身血糖数据进行血糖预测模型的验证,若预测值与真实值的误差在阈值内,则血糖预测模型构建完成。The model verification module uses the processed patient's own blood glucose data to verify the blood glucose prediction model. If the error between the predicted value and the actual value is within the threshold, the blood glucose prediction model is constructed.
  12. 根据权利要求11所述的电子设备,其中,执行所述数据处理模块的功能时,还将血糖数据划分为两部分,一部分用于模型训练模块对血糖预测模型进行训练,另一部分用于模型验证模块对血糖预测模型进行验证。The electronic device according to claim 11, wherein when performing the function of the data processing module, the blood glucose data is further divided into two parts, one part is used for the model training module to train the blood glucose prediction model, and the other part is used for model verification The module validates the blood glucose prediction model.
  13. 根据权利要求9所述的电子设备,其中,执行所述数据采集单元的功能时,还执行如下模块的功能:The electronic device according to claim 9, wherein, when the function of the data acquisition unit is performed, the function of the following modules is also performed:
    数据标注模块,用于对血糖数据的所处的模式进行标注得到所处模式标签,以及用于血糖数据的异常情况进行标注得到异常发生标签,并将所处模式标签和异常发生标签上传至模型构建单元,以构建血糖预测模型;其中,根据血糖数据采集时患者所进行的活动, 或血糖数据采集时所处的时间段,对血糖数据的所处的模式进行标注。The data labeling module is used to label the mode of the blood glucose data to obtain the mode label, and to label the abnormal situation of the blood glucose data to obtain the abnormal occurrence label, and upload the mode label and the abnormal occurrence label to the model. A construction unit is used to construct a blood glucose prediction model; wherein, according to the activities performed by the patient when the blood glucose data is collected, or the time period in which the blood glucose data is collected, the mode of the blood glucose data is marked.
  14. 根据权利要求9所述的电子设备,其中,至少一个处理器还能够执行个性化糖尿病健康管理系统中如下单元的功能:The electronic device of claim 9, wherein the at least one processor is further capable of performing the functions of the following units in the personalized diabetes health management system:
    录入调用单元,用于录入患者基本信息,以及根据患者基本信息调用采用所述患者自身的血糖数据进行训练得到的血糖预测模型。The input calling unit is used for inputting the basic information of the patient, and calling the blood glucose prediction model obtained by training with the blood glucose data of the patient according to the basic information of the patient.
  15. 根据权利要求9所述的电子设备,其中,所述血糖预测模型的输入的血糖数据为时间T到T+t的时序变化的血糖数据,输出的血糖预测值为T+t到T+t+Δt的血糖预测序列的平均值。The electronic device according to claim 9, wherein the input blood sugar data of the blood sugar prediction model is blood sugar data of time series change from time T to T+t, and the output blood sugar prediction value is T+t to T+t+ The mean of the blood glucose prediction series for Δt.
  16. 根据权利要求9所述的电子设备,其中,所述血糖异常阈值,包括:任何模式下的低血糖预警阈值、休闲模式下的血糖最高阈值、和饮食模式下的血糖最高阈值,其中,所述饮食模式下的血糖最高阈值高于休闲模式下的血糖最高阈值。The electronic device according to claim 9, wherein the abnormal blood glucose threshold includes: a low blood sugar warning threshold in any mode, a maximum blood glucose threshold in a leisure mode, and a maximum blood glucose threshold in a diet mode, wherein the The maximum blood glucose threshold in the eating mode was higher than that in the leisure mode.
  17. 一种计算机可读存储介质,存储有计算机程序,其中,所述计算机程序被处理器执行时实现个性化糖尿病健康管理系统中如下各单元的功能:A computer-readable storage medium storing a computer program, wherein, when the computer program is executed by a processor, the functions of the following units in a personalized diabetes health management system are realized:
    数据采集单元,用于获取患者所处的模式,并采集患者在所述模式下时序变化的血糖数据,其中,所述模式包括:睡眠模式、饮食模式、运动模式和休闲模式;a data acquisition unit, configured to acquire the mode in which the patient is located, and to acquire the blood glucose data of the patient with time series changes in the mode, wherein the mode includes: a sleep mode, a diet mode, an exercise mode and a leisure mode;
    血糖预测单元,用于将所述血糖数据输入到血糖预测模型中进行预测,并通过血糖预测模型输出未来一段时间内的血糖预测值,其中,所述血糖预测模型是在所述模式下通过采用患者自身的数据进行训练得到;A blood sugar prediction unit, configured to input the blood sugar data into a blood sugar prediction model for prediction, and output a blood sugar prediction value in a future period of time through the blood sugar prediction model, wherein the blood sugar prediction model is performed in the mode by using The patient's own data is trained;
    比较单元,用于比较所述血糖预测值与预先设定的血糖异常阈值,若所述血糖预测值超出血糖异常阈值,则发出预警提醒。A comparison unit, configured to compare the predicted blood glucose value with a preset blood glucose abnormality threshold, and issue an early warning reminder if the blood glucose predicted value exceeds the blood glucose abnormality threshold.
  18. 根据权利要求17所述的计算机可读存储介质,其中,所述计算机程序被处理器执行时,还实现个性化糖尿病健康管理系统中如下单元的功能:The computer-readable storage medium according to claim 17, wherein, when the computer program is executed by the processor, it further implements the functions of the following units in the personalized diabetes health management system:
    模型构建单元,用于采用LSTM算法构建不同模式下的血糖预测模型。The model building unit is used to build blood glucose prediction models in different modes by using the LSTM algorithm.
  19. 根据权利要求17所述的计算机可读存储介质,其中,所述计算机程序被处理器执行时,还实现所述数据采集单元中如下模块的功能:The computer-readable storage medium according to claim 17, wherein, when the computer program is executed by the processor, the functions of the following modules in the data acquisition unit are further implemented:
    数据标注模块,用于对血糖数据的所处的模式进行标注得到所处模式标签,以及用于血糖数据的异常情况进行标注得到异常发生标签,并将所处模式标签和异常发生标签上传至模型构建单元,以构建血糖预测模型;其中,根据血糖数据采集时患者所进行的活动,或血糖数据采集时所处的时间段,对血糖数据的所处的模式进行标注。The data labeling module is used to label the mode of the blood glucose data to obtain the mode label, and to label the abnormal situation of the blood glucose data to obtain the abnormal occurrence label, and upload the mode label and the abnormal occurrence label to the model A construction unit is used to construct a blood glucose prediction model; wherein, according to the activities performed by the patient when the blood glucose data is collected, or the time period in which the blood glucose data is collected, the mode of the blood glucose data is marked.
  20. 根据权利要求17所述的计算机可读存储介质,其中,所述计算机程序被处理器执行时,还实现个性化糖尿病健康管理系统中如下单元的功能:The computer-readable storage medium according to claim 17, wherein, when the computer program is executed by the processor, it further implements the functions of the following units in the personalized diabetes health management system:
    录入调用单元,用于录入患者基本信息,以及根据患者基本信息调用采用所述患者自身的血糖数据进行训练得到的血糖预测模型。The input calling unit is used for inputting the basic information of the patient, and calling the blood glucose prediction model obtained by training with the blood glucose data of the patient according to the basic information of the patient.
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