WO2022065972A3 - Composition for prevention or treatment of coronavirus infection including epimedium koreanum extract - Google Patents

Composition for prevention or treatment of coronavirus infection including epimedium koreanum extract Download PDF

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Publication number
WO2022065972A3
WO2022065972A3 PCT/KR2021/013197 KR2021013197W WO2022065972A3 WO 2022065972 A3 WO2022065972 A3 WO 2022065972A3 KR 2021013197 W KR2021013197 W KR 2021013197W WO 2022065972 A3 WO2022065972 A3 WO 2022065972A3
Authority
WO
WIPO (PCT)
Prior art keywords
coronavirus
prevention
treatment
epimedium koreanum
koreanum extract
Prior art date
Application number
PCT/KR2021/013197
Other languages
French (fr)
Korean (ko)
Other versions
WO2022065972A2 (en
Inventor
마진열
조원경
Original Assignee
한국한의학연구원
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020210067201A external-priority patent/KR102570595B1/en
Application filed by 한국한의학연구원 filed Critical 한국한의학연구원
Publication of WO2022065972A2 publication Critical patent/WO2022065972A2/en
Publication of WO2022065972A3 publication Critical patent/WO2022065972A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medical Informatics (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention relates to antiviral use against coronavirus, including an Epimedium koreanum extract or a fragment thereof and, more particularly, to: an antiviral pharmaceutical composition against coronavirus, including an Epimedium koreanum extract or a fraction thereof; a pharmaceutical composition for the prevention or treatment of coronavirus infection disease; a method for the prevention or treatment of coronavirus infection disease with the pharmaceutical composition; a health functional food composition for the prevention or treatment of coronavirus infection disease, including an Epimedium koreanum extract or a fragment thereof; and a feed composition for the prevention or treatment of coronavirus inflection disease, including an Epimedium koreanum extract or a fraction thereof. The Epimedium koreanum extract of the present invention exhibits an inhibitory effect on inflection by coronaviruses such as MERS-coronavirus, SARS-coronavirus, and SARS-coronavirus-2, and thus, can be utilized in the development of antiviral drugs for the prevention or treatment of the viral diseases.
PCT/KR2021/013197 2020-09-28 2021-09-28 Composition for prevention or treatment of coronavirus infection including epimedium koreanum extract WO2022065972A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2020-0126187 2020-09-28
KR20200126187 2020-09-28
KR1020210067201A KR102570595B1 (en) 2020-09-28 2021-05-25 Composition for preventing or treating corona virus comprising Epimedium koreanum extracts
KR10-2021-0067201 2021-05-25

Publications (2)

Publication Number Publication Date
WO2022065972A2 WO2022065972A2 (en) 2022-03-31
WO2022065972A3 true WO2022065972A3 (en) 2022-05-19

Family

ID=80846812

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2021/013197 WO2022065972A2 (en) 2020-09-28 2021-09-28 Composition for prevention or treatment of coronavirus infection including epimedium koreanum extract

Country Status (1)

Country Link
WO (1) WO2022065972A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110039079A (en) * 2009-10-09 2011-04-15 한국 한의학 연구원 Composition for prevention or treating porcine epidemic diarrhea containing contract of epimedium koreanum
KR20110049691A (en) * 2009-11-04 2011-05-12 한국 한의학 연구원 Composition for prevention or treatment of disease originated from influenza virus
KR20160019834A (en) * 2014-08-12 2016-02-22 한국 한의학 연구원 Composition for the prevention and treatment of antiviral comprising extracts of Epimedium koreanum

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110039079A (en) * 2009-10-09 2011-04-15 한국 한의학 연구원 Composition for prevention or treating porcine epidemic diarrhea containing contract of epimedium koreanum
KR20110049691A (en) * 2009-11-04 2011-05-12 한국 한의학 연구원 Composition for prevention or treatment of disease originated from influenza virus
KR20160019834A (en) * 2014-08-12 2016-02-22 한국 한의학 연구원 Composition for the prevention and treatment of antiviral comprising extracts of Epimedium koreanum

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BHUIYAN FARHANA RUMZUM, HOWLADER SABBIR, RAIHAN TOPU, HASAN MAHMUDUL: "Plants Metabolites: Possibility of Natural Therapeutics Against the COVID-19 Pandemic", FRONTIERS IN MEDICINE, vol. 7, XP055929542, DOI: 10.3389/fmed.2020.00444 *
CHO WON-KYUNG, KIM HYUNIL, CHOI YU JEONG, YIM NAM-HUI, YANG HYE JIN, MA JIN YEUL: "Epimedium koreanum Nakai Water Extract Exhibits Antiviral Activity against Porcine Epidermic Diarrhea Virus In Vitro and In Vivo", EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, OXFORD UNIVERSITY PRESS, US, vol. 2012, 1 January 2012 (2012-01-01), US , pages 1 - 10, XP055929543, ISSN: 1741-427X, DOI: 10.1155/2012/985151 *
CHO WON-KYUNG, WEERATUNGA PRASANNA, LEE BYEONG-HOON, PARK JUN-SEOL, KIM CHUL-JOONG, MA JIN, LEE JONG-SOO: "Epimedium koreanum Nakai Displays Broad Spectrum of Antiviral Activity in Vitro and in Vivo by Inducing Cellular Antiviral State", VIRUSES, vol. 7, no. 1, 1 January 2015 (2015-01-01), pages 352 - 377, XP055929540, DOI: 10.3390/v7010352 *
SHIN, HYUN-SOO: "Coronavirus Replication Inhibition by Herbal Extracts", MASTER THESIS, 1 February 2007 (2007-02-01), Korea, pages 1 - 31, XP009536717 *

Also Published As

Publication number Publication date
WO2022065972A2 (en) 2022-03-31

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