WO2021227437A1

WO2021227437A1 - Test cup for thrombelastogram test

Info

Publication number: WO2021227437A1
Application number: PCT/CN2020/130902
Authority: WO
Inventors: 李钢; 范志明
Original assignee: 常熟常江生物技术有限公司
Priority date: 2020-05-12
Filing date: 2020-11-23
Publication date: 2021-11-18

Abstract

A test cup for a thrombelastogram test, consisting of a cup body (1) and a swing rod (2). The swing rod (2) is of a V-shaped structure consisting of a stress rod (22) and a test rod (21). The test rod (21) extends into the cup body (1). The stress rod (22) is located outside the cup body (1). The cup body (1) comprises a supporting structure. An inner groove (23) on a top end of the V-shaped structure of the swing rod (2) is connected to the supporting structure of the cup body (1) by means of line contact, so that the swing rod (2) can swing relative to the cup body (1). The test rod (21) is located in the cup body (1) and immersed into a blood sample, and the stress rod (22) is located outside the cup body (1). During detection, a detection unit component of a detection instrument is connected to the stress rod (22) to drive the swing rod (2) to swing, and the changes in the viscosity and the elasticity of the blood sample are obtained according to the torque change generated when detecting an action of the swing rod (2). A connecting structure between the inner groove (23) on the top end of the V-shaped structure of the swing rod, and the cup body (1) has an extremely small contact area, so that the swing rod (2) can swing approximately without resistance, ensuring that the tests of the viscosity and the elasticity of the blood sample are not affected by interference resistance, and more accurate data can be obtained.

Description

Test cup for thrombus elastic graph test

Technical field

The invention belongs to the field of medical test equipment, and specifically relates to a test cup.

Background technique

The thromboelastogram (TEG) is an indicator that reflects the dynamic changes of blood coagulation. The test results directly guide the doctor's medication, so the accuracy of the patient's blood test is very important. As the carrier in the test process, the test cup is also an important component of the test method, and plays an indispensable role in the accuracy and stability of the test results.

Summary of the invention

The technical problem to be solved by the present invention is to provide a high-efficiency sample test method, and meet the requirements of keeping the test cup at a constant temperature and fixing the relative position of the sensor and the test cup during the test.

In order to solve the above technical problems, the present invention provides a test cup for thrombus elasticity graph testing, which is composed of a cup body and a pendulum rod. The pendulum rod has a V-shaped structure composed of a force rod and a test rod, and the test rod extends into the cup body. , The force-bearing rod is located outside the cup body, the cup body includes a supporting structure, and the top inner groove of the swing rod V-shaped structure is connected with the supporting structure through line contact, so that the pendulum rod can swing relative to the cup body.

Further, the top end of the support structure has an acute angle shape, and the top end inner groove of the V-shaped structure is a square groove, so that the top end of the support structure abuts against a corner of the top end inner groove of the swing bar V-shaped structure.

Further, the front cup wall of the cup body is set as a multi-level inclined surface and closes to the rear cup wall of the cup body, and the supporting structure of the cup body is arranged on the first level inclined surface of the front cup wall of the cup body.

Further, the two side walls of the cup body are vertically arranged in parallel or narrowed from top to bottom, and the rear cup wall is inclined to the front cup wall.

Further, the bottom of the test rod is an L-shaped test head, and the test head is set to be completely immersed in the blood sample during use.

Further, the width of the test head is set to be as small as possible as much as possible to be smaller than the inner cavity of the cup body under the premise of ensuring a sufficient force-bearing area, so as to ensure that the sample flows smoothly when the pendulum rod swings.

Further, the lower part of the force-bearing rod is provided with a transverse square strip, and the two side walls of the cup body are narrowed in the upper direction of the square strip, so that the two ends of the square strip extend beyond the inner surface of the two side walls of the cup body.

Further, the cup body is injection molded with plastic materials.

Further, the pendulum rod is injection molded with plastic materials.

Further, a plurality of test cups for thromboelastogram testing as described above are connected and formed along the side direction of the cup body.

The advantage of the present invention is that the test rod is located in the cup body and immersed in the blood sample, and the force rod is located outside the cup. During detection, the detection unit assembly of the detection instrument is connected with the force rod to drive the pendulum rod to swing and pass the detection of the pendulum rod movement. When the torque changes, the viscosity and elastic changes of the blood sample are obtained. The connecting structure between the inner groove of the V-shaped structure of the pendulum rod and the cup body has a very small contact area, so that the pendulum rod can swing approximately without resistance, ensuring that the viscosity and elasticity of the blood sample are not affected by interference resistance when testing the blood sample. Accurate data.

Description of the drawings

Figure 1 is a three-dimensional schematic diagram of a single test cup;

Figure 2 is a perspective view of a cross-sectional view of a single test cup;

Figure 3 is a front view of a cross-sectional view of a single test cup;

Figure 4 is a top view of a single test cup;

Figure 5 is a front view of a single test cup;

Figure 6 is a front view of a test cup in the form of a coupler.

Detailed ways

The present invention will be described in detail below in conjunction with the drawings and specific embodiments:

As shown in Figures 1 to 5, a test cup for thrombus elasticity graph testing is composed of a cup body 1 and a pendulum rod 2. The pendulum rod 2 has a V-shaped structure composed of a force rod 22 and a test rod 21. The test rod 21 Extending into the cup body 1, the force-bearing rod 22 is located outside the cup body 1. The cup body 1 includes a supporting structure. The pendulum rod 2 can swing relative to the cup body 1.

The test rod 21 is located in the cup body 1 immersed in the blood sample, and the force rod 22 is located outside the cup body 1. During detection, the detection unit assembly of the testing instrument is connected with the force rod 22 to drive the pendulum rod 2 to swing and pass the detection pendulum rod 2 The torque changes generated during the action, and the viscosity and elastic changes of the blood sample are obtained. The connecting structure between the inner groove 23 of the top end of the pendulum rod V-shaped structure and the cup body 1 has a very small contact area, so that the pendulum rod can swing approximately without resistance, ensuring that the viscosity and elasticity of the blood sample are not affected by interference resistance when testing the viscosity and elasticity of the blood sample. Obtain more accurate data.

Preferably, the top end of the support structure of the cup body 1 has an acute-angle shape, the inner groove 23 at the top end of the swing bar V-shaped structure is a square groove (or called a rectangular groove), and the top end of the cup body support structure abuts against the top end of the swing bar V-shaped structure. A corner of the groove 23 is shown in FIGS. 2 and 3.

Preferably, the front cup wall 11 of the cup body 1 is set to be close to the rear cup wall 12 of the cup body 1 with multiple slopes, and the supporting structure of the cup body 1 is provided on the first slope surface 111 of the front cup wall of the cup body, as shown in the figure 3 shown. The front cup wall 11 is provided with a multi-level inclined surface structure, which not only allows the force rod 22 to be in a natural vertical downward state in the initial position, but also narrows the inner cavity at the bottom of the cup body 1 to make blood samples more concentrated.

Preferably, the two side walls 13 of the cup body 1 are vertically arranged in parallel or narrowly arranged from top to bottom, and the rear cup wall 12 of the cup body 1 is arranged obliquely to the front cup wall 11, as shown in Figs. 3 and 4. The structure can narrow the inner cavity at the bottom of the cup body 1 and make blood samples more concentrated.

Preferably, the bottom of the test rod 21 is an L-shaped test head 211, and the test head 211 is completely immersed in the blood sample when in use, as shown in FIGS. 2 and 3. The detection principle of the test cup is to analyze the change of blood viscosity by detecting the resistance torque received during the swing of the pendulum rod 2, and the blood will flow along the wall of the pendulum rod 2 that it contacts, and the viscosity is different. The speed of the flow will also be different. Therefore, in order to ensure that the test head 211 is made into an L shape each time it swings, the test head 211 is made into an L shape to block the flow of the fluid along the wall of the pendulum rod 1 within the instant of sampling.

Preferably, the width of the test head 211 should be as small as possible to be smaller than the inner cavity of the cup body 1 under the premise of ensuring a sufficient force-bearing area, so as to ensure that the sample flows smoothly when the pendulum rod 2 swings, as shown in FIG. 4. Because the fluid is an incompressible object, when the pendulum rod 2 swings, the liquid in the forward direction of the swing will flow to the back of the L-shaped test head 211, and the pendulum rod 2 detects the change in the viscosity of the liquid. In order to avoid the influence of the gravity of the liquid, To make the liquid flow smoothly and prevent the liquid level from rising, it is necessary to ensure that there is a large enough gap between the pendulum rod 2 and the cup body 1.

Preferably, the lower part of the force-bearing rod 22 is provided with a transverse square strip 221, and the two side walls 13 of the cup body 1 are narrowed in the upper direction of the square strip 221, so that the two ends of the square strip 221 extend beyond the two sides of the cup body 1. The position of the inner surface of the side wall 13 is shown in FIGS. 1 and 5. The extension length of the square bar 221 can prevent the pendulum rod 2 from falling when the cup body 1 is arbitrarily placed, and the square bar 221 is also convenient for the detection unit assembly of the detection instrument to grasp the pendulum rod 2.

Preferably, both the cup body 1 and the swing rod 2 are injection-molded with plastic materials.

In actual detection, in order to improve the detection efficiency, multiple (for example, 2, 3, 4, 5, 6, 7, 8 or 9) test cups are often used. The test cups of the present invention can also be connected. The cup form, as shown in Fig. 6, utilizes a plurality of test cups to be connected and formed along the side of the cup body to form a coupler for use. When the cup body 1 is injection-molded, this union cup structure is very easy to implement, and only a certain thickness of plastic material needs to be added between the side cup walls of two adjacent test cups.

It should be emphasized that the above are only the preferred embodiments of the present invention, and are not intended to limit the present invention in any form. Any simple modification, equivalent change and modification made to the above embodiments based on the technical essence of the present invention are all. It still falls within the scope of the technical solution of the present invention.

Claims

A test cup for thrombus elastic map testing, which is characterized in that it is composed of a cup body and a swing rod, the swing rod has a V-shaped structure composed of a force rod and a test rod, and the test rod extends into the cup body , The force-bearing rod is located outside the cup, the cup body includes a supporting structure, and the inner groove of the top end of the V-shaped structure is connected with the supporting structure through line contact, so that the swing rod is relative to The cup body can swing.
The test cup for thromboelastogram testing according to claim 1, wherein the top end of the support structure is an acute-angled shape, and the top end inner groove of the V-shaped structure is a square groove, so that the top end of the support structure Lean against a corner of the inner groove at the top of the V-shaped structure.
The test cup for thromboelastogram testing according to claim 1, wherein the front cup wall of the cup body is set as a multi-level slope and is close to the rear cup wall of the cup body, and the cup body supports The structure is arranged on the first slope of the front cup wall.
The test cup for thromboelastogram testing according to claim 1, wherein the two side walls of the cup body are vertically arranged in parallel or narrowed from top to bottom, and the rear cup wall faces the front The cup wall is inclined.
The test cup for thromboelastogram testing according to claim 1, wherein the bottom of the test rod is an L-shaped test head, and the test head is configured to be completely immersed in the blood sample during use.
The test cup for thromboelastogram testing according to claim 5, wherein the width of the test head is set to be as small as possible than the inner cavity of the cup body under the premise of ensuring a sufficient force-bearing area. The sample flows smoothly when the swing lever swings.
The test cup for thromboelastogram testing according to claim 1, characterized in that: the lower part of the force rod is provided with a transverse square strip, and the two side walls of the cup body are in the upper direction of the square strip. It is narrowed so that the two ends of the square bar extend to a position beyond the inner surface of the two side walls of the cup body.
The test cup for thromboelastogram testing according to claim 1, wherein the cup body is injection molded with plastic material.
The test cup for thromboelastogram testing according to claim 1, wherein the swing rod is injection molded with plastic material.
A test cup for thromboelastogram testing in the form of a double cup, characterized in that: a plurality of test cups for thromboelastogram testing according to any one of claims 1-9 are connected and formed along the side of the cup body .