WO2021221198A1

WO2021221198A1 - Personal coronavirus antibody detecting kit set

Info

Publication number: WO2021221198A1
Application number: PCT/KR2020/005636
Authority: WO
Inventors: 김형곤
Original assignee: 주식회사 메덱스
Priority date: 2020-04-28
Filing date: 2020-04-28
Publication date: 2021-11-04

Abstract

A personal coronavirus antibody detecting kit set according to the present invention is characterized in that a disposable blood collector for collecting the blood of a user, a disposable pipette for collecting the blood of the user, a test cassette for detecting coronavirus by analyzing the blood, a single-use reagent for promoting analysis when analyzing the blood in the test cassette; an alcohol swab for sterilizing the blood collection site, and disposable latex gloves to be worn by the user during blood collection are integrally packaged.

Description

Personal Corona Antibody Diagnostic Kit Set

The present invention relates to a personal corona antibody diagnostic kit set, and more particularly, to a personal diagnostic kit set that can be carried and conveniently diagnosed by an individual.

Diagnosis of coronavirus is classified into molecular test and serology test. The most commonly used diagnostic method is a molecular diagnostic method, which is performed by PCR or gene sequencing using a virus gene-specific primer from a nasal swap sample. Serological diagnosis of coronavirus uses the principle of antigen-antibody reaction, and there are antibody diagnostic ELISA (enzyme-linked immunosorbent assay, enzyme-linked immunosorbent assay) for S antigen or NC antigen, or microneutralization assay. The antibody diagnostic kit developed by Euroimmune (Germany) is used for diagnosing the coronavirus using the Indirect ELISA method based on the purified S1 antigen.

The antigen diagnostic kit is a method to check the presence or absence of N protein that COVID-19 self-replicates, and the test accuracy reaches 85%. Although the accuracy of the RT-PCR (Real-Time Reverse Transcription Polymerase Chain Reaction) gene test conducted by the government is somewhat lower, RT-PCR has a fatal disadvantage in that it has to wait for 6 hours, including the time for specimen transport and test preparation time. there was.

The antigen diagnostic kit can check the presence of infection in just 10 minutes through runny nose and sputum, and the antibody diagnostic kit through blood.

In the case of antibody diagnosis, it is a test method based on serological changes, and since it targets blood, there is no inaccuracy in sample collection, and it has the advantage of low risk like the existing upper airway and lower respiratory tract samples. Antibody test is a method to test the initial antibodies IgM and IgG produced in our body after virus infection in the blood. Antibody diagnosis has the advantage that anyone can do it without having to be an expert.

However, the conventional antibody diagnostic kit has a problem in that it is necessary to visit a hospital for blood collection. Although it takes only 10 minutes to diagnose the test, there is a problem in that the actual test takes a lot of time because it requires a visit to a hospital or a medical team to collect blood.

The present invention is to solve this problem, and it is an object of the present invention to provide a personal corona antibody diagnostic kit set that can be easily used by anyone by having a test cassette and a disposable blood collection device integrally.

The personal corona antibody diagnostic kit set according to the present invention includes a disposable blood collection device for collecting a user's blood, a disposable dropper for collecting the user's blood; a test cassette for diagnosing corona by analyzing the blood; a disposable reagent for facilitating analysis of blood in the test cassette; alcohol swab to disinfect the blood sampled area; And it is characterized in that the disposable latex gloves for the user to wear when collecting blood is integrally packaged.

In an embodiment of the present invention, the disposable blood collection device includes a case; a trigger that is inserted into the case and has a through hole through which a needle can pass, a slit of a long shape is symmetrically formed on the body, and a part protrudes toward the front of the case; a lancet comprising a percussion unit coupled to the needle and coupled to the slit, a spring supporting the percussion unit, and a rear cover supporting the spring and coupled to the rear end of the case; and a lid protecting the trigger, wherein when the trigger is pressed while the lid is removed, the lancet is triggered to collect blood.

In an embodiment of the present invention, the disposable reagent comprises deionized water, sodium chloride, and ethanol iodine.

According to the present invention, a user can easily diagnose whether or not the Corona 19 virus is present without visiting a hospital or medical institution.

In addition, according to the present invention, it is possible to diagnose whether or not the Corona-19 virus is present in a short time regardless of location, and even asymptomatic infection can be diagnosed in a short time, thereby preventing unnecessary isolation. Therefore, the time and cost required for isolation can be reduced.

1 shows the configuration of a personal corona antibody diagnostic kit set according to the present invention.

Figure 2 shows the detailed configuration of the disposable blood sampling machine.

3 shows the packaging box of the personal corona antibody diagnostic kit set according to the present invention.

Since the present invention can have various changes and can have various embodiments, specific embodiments are illustrated in the drawings and described in detail in the detailed description. However, this is not intended to limit the present invention to specific embodiments, and it should be understood to include all modifications, equivalents and substitutes included in the spirit and scope of the present invention. In describing the present invention, if it is determined that a detailed description of a related known technology may obscure the gist of the present invention, the detailed description thereof will be omitted.

Terms such as first, second, A, and B may be used to describe various elements, but the elements should not be limited by the terms. The above terms are used only for the purpose of distinguishing one component from another. For example, without departing from the scope of the present invention, a first component may be referred to as a second component, and similarly, a second component may also be referred to as a first component. and/or includes a combination of a plurality of related listed items or any of a plurality of related listed items.

The terms used in the present application are only used to describe specific embodiments, and are not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly dictates otherwise. In the present application, terms such as “comprise” or “have” are intended to designate that a feature, number, step, operation, component, part, or combination thereof described in the specification exists, but one or more other features It should be understood that this does not preclude the existence or addition of numbers, steps, operations, components, parts, or combinations thereof.

Hereinafter, the configuration of the present invention will be described in detail with reference to the accompanying drawings.

Figure 1 shows a personal corona antibody diagnostic kit set according to the present invention. Figure 1 (a) shows individual components, and Figure 1 (b) shows a package including these components. FIG. 2 is a detailed view of the blood sampling machine of FIG. 1 , and FIG. 3 is a view showing the packaging box together.

A personal corona antibody diagnostic kit set according to the present invention includes a disposable blood sampler 10 for collecting a user's blood, a disposable eyedropper 20 for collecting the user's blood, and a test cassette for diagnosing corona by analyzing the blood. (30), a disposable reagent 40 for facilitating the analysis when the blood of the test cassette is analyzed, and a disposable alcohol swab 50 for sterilizing the blood sample may be integrally packaged.

And disposable latex gloves 60 for preventing contamination during blood collection may be further added.

The disposable blood collection device 10 is a personal blood collection device that can simply collect blood without going to a hospital.

Referring to FIG. 2 , the blood collection device 10 includes a case 11 , a trigger 12 , a lancet 13 , a rear cover 14 , and a lid 15 .

The trigger 12 is inserted into the case 11 so that a through hole 121 through which a needle can pass is formed, and a slit 122 having an elongated shape is symmetrically formed on the body. A part of the body protrudes toward the front of the case and serves as an operation switch.

The lancet 13 includes a percussion part 131 to which a needle is coupled and coupled to the slit, and a spring 132 for supporting the percussion part.

The rear cover 14 serves to block the rear of the case and support the spring 132 .

The lid 15 is coupled to the front of the case to protect the trigger. It is possible to prevent the protruding trigger from arbitrarily triggering, and it is possible to prevent an accident of being stabbed by a needle.

The disposable dropper 20 is for collecting blood collected by a blood collection device. When the disposable dropper 20 is in contact with the blood on the finger, the blood is sucked into the disposable dropper by the pressure difference.

The test cassette 30 is a test kit for diagnosing blood, and a general antibody diagnostic cassette sold in the market may be used. The test cassettes are striped in either the M or G regions in response to IgM and IgG antibodies. If the IgM antibody is positive, a stripe is formed in the M region, and if the IgG antibody is positive, a stripe is formed in the G region. Therefore, if both IgM and IgG antibodies are positive, both stripes may be formed.

The disposable reagent 40 is for facilitating the antibody diagnosis of the test cassette 30, and a mixed solution composed of deionized water, sodium chloride, and ethanol iodine may be used. Specifically, deionized water may include 96.55 wt%, sodium chloride 0.85 wt%, and ethanol iodine (Nonylphenoxypoly(ethylenoxy) ethanol) 2.5 wt%. In addition, 0.1% by weight of Kathon 886 may be included.

The disposable alcohol swab 50 is to prevent contamination, and is used to disinfect the site to be collected before blood collection.

The disposable latex gloves may be provided to prevent infection.

As described above, the disposable blood sampler, disposable dropper, test cassette, disposable reagent, disposable alcohol swab, and disposable latex gloves are provided as a set and packaged in one box. Corona infection can be easily diagnosed regardless of location.

The examination method using the diagnostic kit set will be briefly described as follows.

First, a user may use a disposable alcohol swab to disinfect a blood collection site, and then use a disposable blood collection device to prick a desired area, such as a finger, to collect blood. When blood is collected on the finger by the blood collection device, it is collected using a disposable dropper and dropped into a test cassette.

After dropping a certain amount of disposable reagent after dropping blood, it is possible to check whether or not the corona-19 virus is infected after about 10 minutes have elapsed.

According to the present invention, since a user can easily diagnose whether or not a corona infection is present anywhere, it is possible to easily check for corona infection even at an airport without a separate quarantine measure.

Therefore, it is possible to prevent the loss of time and money caused by isolation.

Although the embodiment has been described above, it is only an example and does not limit the present invention, and those of ordinary skill in the art to which the present invention pertains are not exemplified above in a range that does not depart from the essential characteristics of the present embodiment. It will be appreciated that various modifications and applications are possible. For example, each component specifically shown in the embodiment can be implemented by modification. And differences related to such modifications and applications should be construed as being included in the scope of the present invention defined in the appended claims.

The present invention can be applied to the field of COVID-19 virus diagnosis.

Claims

a blood sampler that collects the user's blood;

a disposable dropper for collecting the user's blood;

a test cassette for diagnosing corona by analyzing the blood;

a disposable reagent for facilitating analysis of blood in the test cassette;

alcohol swab to disinfect the blood sampled area; and

A personal corona antibody diagnostic kit set, characterized in that disposable latex gloves to be worn by the user when collecting blood are packaged in one piece.
The method of claim 1, wherein the blood collection device

case,

a trigger that is inserted into the case and has a through hole through which a needle can pass, a slit of a long shape is symmetrically formed on the body, and a part protrudes toward the front of the case;

a lancet comprising a percussion unit coupled to the needle and coupled to the slit, a spring supporting the percussion unit, and a rear cover supporting the spring and coupled to the rear end of the case;

a lid protecting the trigger;

A personal corona antibody diagnostic kit set, characterized in that when the trigger is pressed while the lid is removed, the lancet is triggered to collect blood.
According to claim 1,

The disposable reagent is a personal corona antibody diagnostic kit set, characterized in that it comprises deionized water, sodium chloride, ethanol iodine.