WO2021159761A1 - Pathological data analysis method and apparatus, and computer device and storage medium - Google Patents

Pathological data analysis method and apparatus, and computer device and storage medium Download PDF

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Publication number
WO2021159761A1
WO2021159761A1 PCT/CN2020/125152 CN2020125152W WO2021159761A1 WO 2021159761 A1 WO2021159761 A1 WO 2021159761A1 CN 2020125152 W CN2020125152 W CN 2020125152W WO 2021159761 A1 WO2021159761 A1 WO 2021159761A1
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data
heart failure
risk
feature
feature data
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PCT/CN2020/125152
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French (fr)
Chinese (zh)
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贾文笑
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平安科技(深圳)有限公司
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/045Combinations of networks
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/08Learning methods
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records

Definitions

  • This application relates to the field of digital medical technology, in particular to a pathological data analysis method, device, computer equipment and storage medium.
  • Heart failure refers to the failure of the systolic and/or diastolic function of the heart, the inability to fully discharge the venous return blood volume out of the heart, resulting in blood stasis in the venous system and insufficient blood perfusion in the arterial system.
  • Cardiac circulatory disorder syndrome which is manifested in clusters of pulmonary congestion and vena cava congestion.
  • Heart failure is not an independent disease, but the final stage of the development of heart disease. Improper treatment can affect health and even threaten life. However, if a greater risk of heart failure can be detected early and effective prevention and treatment measures can be taken in time, it will be of great significance to improve the prognosis and mortality of patients.
  • the main purpose of this application is to provide an analysis method, device, computer equipment and storage medium for pathological data, which aims to solve the problem that the existing prediction methods for the risk of heart failure are still based on traditional empirical judgments, which are time-consuming, labor-intensive and accurate. Technical problems with low sexuality.
  • This application proposes a method for analyzing pathological data.
  • the method includes the steps:
  • the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
  • the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data
  • the fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight.
  • Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
  • the output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  • This application also provides a device for predicting the risk of heart failure, including:
  • Collection module used to collect pathological data of users
  • the extraction module is used for feature extraction of the pathological data to obtain specified feature data related to the risk of heart failure, wherein the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
  • the first acquisition module is configured to acquire structured characteristic data of the user related to the risk of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
  • a processing module configured to perform splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing
  • the first generation module is configured to use the fusion feature data as the input of the preset attention module, and generate the attention weight corresponding to each fusion feature in the fusion feature data through the attention module, and Performing weighted summation processing on each fusion feature in the fusion feature data according to the attention weight to obtain a corresponding output result;
  • the second generation module is configured to input the output result into a preset classification module, and normalize the output result through the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  • the present application also provides a computer device, including a memory and a processor, the memory stores a computer program, and the processor implements a pathological data analysis method when the computer program is executed, wherein the pathological data
  • the analysis method includes the following steps:
  • the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
  • the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data
  • the fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight.
  • Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
  • the output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  • the present application also provides a computer-readable storage medium on which a computer program is stored, and when the computer program is executed by a processor, a method for analyzing pathological data is realized, wherein the method for analyzing pathological data includes the following steps:
  • the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
  • the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data
  • the fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight.
  • Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
  • the output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  • the pathological data analysis method, device, computer equipment and storage medium provided in this application can intelligently and accurately generate the prediction probability of the user’s heart failure, realize the accurate prediction of the user’s heart failure risk, and effectively improve the prediction of the user’s heart failure.
  • FIG. 1 is a schematic flowchart of a method for locating the root cause of an alarm according to an embodiment of the present application
  • FIG. 2 is a schematic structural diagram of an apparatus for locating the root cause of an alarm according to an embodiment of the present application
  • Fig. 3 is a schematic structural diagram of a computer device according to an embodiment of the present application.
  • This solution can be applied to the digital medical field in smart cities, thereby promoting the construction of smart cities.
  • the pathological data analysis method of an embodiment of the present application includes:
  • S1 Collect pathological data of users
  • S2 Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
  • S3 Obtain structured characteristic data of the user related to the risk of heart failure, where the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
  • S4 Perform splicing processing on the designated feature data and the structured feature data to obtain merged feature data after the splicing process;
  • the fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is generated according to the attention Weight performs weighted summation processing on each fusion feature in the fusion feature data to obtain a corresponding output result;
  • S6 Input the output result to a preset classification module, and normalize the output result through the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  • the execution subject of this method embodiment is a heart failure risk prediction device.
  • the above-mentioned heart failure risk prediction device can be realized by a virtual device, such as software code, or by a physical device written or integrated with relevant execution codes, and can communicate with the user through a keyboard, mouse, remote control, Human-computer interaction is carried out by means of touchpad or voice control equipment.
  • the heart failure risk prediction device in this embodiment can intelligently and accurately generate the user's heart failure prediction probability, realizes accurate prediction of the user's heart failure risk, and effectively improves the processing efficiency for predicting the user's heart failure risk. Specifically, first collect the pathological data of the user.
  • multiple data sources can be used to collect the user's pathological data during the preset historical time period.
  • the aforementioned data sources are not specifically limited.
  • they can include electronic medical record systems, user's disease shooting or scanning files, etc.; and
  • the aforementioned preset historical time period is not specifically limited, and may be, for example, the past two years.
  • the above-mentioned pathological data may include at least physiological signal data, vital signs data, case text data and other data.
  • feature extraction is performed on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data.
  • different feature extraction methods will be used for pathological data of different modalities.
  • convolutional neural networks can be used to extract the above-mentioned physiological signal feature data
  • recurrent neural networks can be used to extract the above-mentioned vital sign feature data
  • Chinese Natural language processing technology extracts case text feature data.
  • the above-mentioned physiological signal characteristic data may include electrocardiographic characteristic data, etc.
  • the above-mentioned vital sign data may include blood pressure characteristic data, heart rate characteristic data, and respiratory rate characteristic data, etc.
  • Related characteristic data such as treatment, family medical history, marital status, etc.
  • obtain the structured characteristic data of the user related to the risk of heart failure where the structured characteristic data includes laboratory test characteristic data and demographic characteristic data, and the laboratory test characteristic data may include blood routine and urine routine.
  • the above-mentioned demographic characteristic data may include characteristic data such as age, gender, and disease history.
  • the laboratory test feature data and demographic feature data in the structured feature data are information that does not change with time, the structured feature data can be extracted directly without the need for feature extraction processing operations.
  • the above-mentioned pathological data may also include user laboratory examination characteristic data and demographic characteristic data, so that the above-mentioned structured characteristic data can be directly obtained from the above-mentioned pathological data.
  • the specified feature data and the structured feature data are spliced to obtain the merged feature data after splicing.
  • a staged integrated learning algorithm can be used to realize the data splicing process between the specified feature data and the structured feature data.
  • the fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated through the attention module, and Perform weighted summation processing on each fusion feature in the fusion feature data according to the above attention weight to obtain a corresponding output result.
  • the process of calculating the attention weight includes: first calculating the attention score of each fusion feature in the fusion feature data, and then using the softmax function to perform numerical conversion on each attention score to generate the attention weight of each fusion feature.
  • Attention weight refers to the weight of the attention degree of each fusion feature, and the sum of all attention weights is 1.
  • e k,j relu(W a h j +b a )
  • W a and b a is the network parameters that can be learned by the attention layer of the model
  • h j is any fusion feature in the fusion feature data
  • relu is the activation function.
  • the formula Perform dot multiplication processing that is, perform weighted summation processing on each fusion feature in the fusion feature data according to the attention weight, and generate the Attention value corresponding to the fusion feature data, that is, the above output result.
  • the aforementioned output result is input to a preset classification module, and the aforementioned output result is normalized by the aforementioned classification module to generate a predicted probability of occurrence of heart failure corresponding to the aforementioned user.
  • O ⁇ is the predicted probability of heart failure
  • the range of O ⁇ is between 0 and 1
  • W c and b c are network parameters that can be learned by the classification module
  • C is the output result of the attention module.
  • This solution can be applied to the digital medical field in smart cities, thereby promoting the construction of smart cities.
  • This application collects multiple modal feature data of users related to the risk of heart failure, and performs splicing processing on the multiple modal feature data, and based on the attention module and the classification module on the fusion feature data generated after the splicing process
  • Data analysis and processing can intelligently and accurately generate the user's heart failure prediction probability, realize the accurate prediction of the user's heart failure risk, and effectively improve the processing efficiency of predicting the user's heart failure risk.
  • the aforementioned attention module is an attention network in the heart failure risk prediction model generated by training
  • the classification module is a classifier in the heart failure risk prediction model
  • the heart failure risk prediction model may further include Feature extraction network for feature extraction.
  • the feature extraction network takes pathological data of heart failure patient data as input, and outputs feature data corresponding to the risk of heart failure after feature extraction processing.
  • the attention network uses the feature data of the patients corresponding to the risk of heart failure and the fusion feature data obtained by splicing the structured feature data of the patients corresponding to the risk of heart failure as input, outputs the attention weight, and integrates the features
  • the data and the corresponding attention weight are weighted and summed to obtain the output result, which is the attention value.
  • the classifier takes the attention value output by the attention network as input, normalizes the attention value, and outputs the classification result.
  • Train the initial model by acquiring pathological data of a preset number of patients as a training sample, using the training sample as the input layer in the initial model, and using the truth label corresponding to the training sample as the output layer of the initial model , Obtain the corresponding feature extraction module, attention module and classification module, and finally generate the above-mentioned heart failure risk prediction model.
  • the training and generation process of the above-mentioned heart failure risk prediction model can refer to the existing model training and generation methods, and will not be repeated here.
  • the above-mentioned feature extraction module corresponds to the above-mentioned feature extraction network
  • the above-mentioned attention module corresponds to the above-mentioned attention network
  • the above-mentioned classification module corresponds to the above-mentioned classifier.
  • the aforementioned training samples also include structured feature data corresponding to the risk of heart failure.
  • step S2 includes:
  • S200 Perform feature extraction on the physiological signal data in the pathological data by using a convolutional neural network to obtain physiological signal feature data corresponding to the physiological signal data;
  • S201 Perform feature extraction on vital sign data in the pathological data by using a cyclic neural network to obtain corresponding vital sign feature data;
  • S202 Use Chinese natural language processing technology to extract key features of the case text data in the pathology data to obtain corresponding case text feature data.
  • the step of extracting features from the pathological data to obtain specified feature data related to the risk of heart failure may specifically include: using a convolutional neural network to extract features from the physiological signal data in the pathological data to obtain the physiological signal data.
  • Corresponding physiological signal characteristic data includes ECG data. Since the physiological signal data belongs to high-density sampling time-series waveform data, the characteristics of the physiological signal data can be extracted by using a convolutional neural network, and the corresponding physiological signal characteristic data can be output.
  • ECG represents the physiological signal data of the user, such as electrocardiogram data
  • CNN represents the convolutional neural network
  • P represents the output physiological signal characteristic data corresponding to the physiological signal data.
  • the recurrent neural network is used to extract the characteristics of the vital sign data in the above-mentioned pathological data to obtain the corresponding vital sign characteristic data.
  • the above vital sign data may include blood pressure, body temperature, respiration and other data. Since the vital sign data belongs to low-density sampling of discontinuous waveform data, the above vital sign data can be feature extracted through a cyclic neural network, and the corresponding vital signs can be output. Physical characteristics data. Recurrent neural networks can effectively consider the timing dependence between data.
  • Q represents the vital sign data of the user
  • RNN represents cyclic neural network, which may include LSTM or GRU network structure, for example
  • Q represents the output vital sign feature data corresponding to the vital sign data.
  • NLP Chinese natural language processing
  • advanced NLP technology can be used to automatically extract based on preset keyword information, such as hypertension, diabetes, anti-hypertensive treatment, family history and marital status, etc., through the combination of Embedding and RNN. Key patient characteristics.
  • V Embedding(word)
  • R RNN(V)
  • word represents the user's case text data
  • Embedding represents the processing of word embedding technology
  • RNN represents cyclic neural network, which may include LSTM or GRU network structure, for example.
  • S [P,Q,R]
  • this embodiment will use the corresponding deep neural network to extract the features of the different modal data, so as to accurately and quickly extract the required specifications from the pathological data.
  • the characteristic data enables the subsequent accurate and quick prediction of the risk of the user's heart failure based on the designated characteristic data.
  • step S201 includes:
  • S2010 Perform feature extraction on vital sign data in the pathological data by using the recurrent neural network to obtain first vital sign feature data;
  • S2011 Determine whether there are missing values in the first vital sign characteristic data
  • S2013 Obtain the last characteristic observation value corresponding to the designated data missing position, and acquire the mean value of the first vital sign characteristic data, wherein the designated data missing position is any data missing position of all the data missing positions ;
  • S2014 According to the last feature observation value and the average value, call a preset calculation formula to calculate the designated filling value corresponding to the designated data missing position; S2015: Use the designated filling value to delete the designated data Position data filling processing;
  • the missing data in the vital sign feature data can be filled in to complete the data processing of the vital sign feature data.
  • the step of using the recurrent neural network to extract features from the vital sign data in the pathological data to obtain the corresponding vital sign feature data includes: first using the recurrent neural network to feature the vital sign data in the pathological data Extract and obtain the first vital sign feature data. Then it is judged whether there are missing values in the first vital sign feature data. If there is a missing value in the first vital sign feature data, the data missing position in the first vital sign feature data is acquired.
  • the last feature observation value corresponding to the designated data missing location is obtained, and the average value of the first vital sign feature data is obtained, where the specified data missing location is any data missing location of all the above data missing locations.
  • a preset calculation formula is called to calculate the designated filling value corresponding to the above-mentioned designated data missing position.
  • x 'd is the mean of the data of the first feature vital signs (also referred to as average experience), It is a mask matrix, indicating whether the current data variable has been observed, if it is observed, the value is 1, and if it is not observed, the value is 0. For example, if at a certain moment, the d-th data variable is observed, then this variable is equal to the observed value at this moment, and if it is not observed, it is indicated as missing data or missing value.
  • the time decay factor corresponding to the network W ⁇ and b ⁇ are network parameters that can be learned by the cyclic neural network, ⁇ t is the time interval between the position of the missing data and the last observation, and ⁇ t will eventually be normalized to a value of 0 ⁇ Within the range of 1.
  • the specified fill value corresponding to the missing position of the specified data needs to be balanced between the last feature observation value and the mean value.
  • the specified filling value is used to perform data filling processing on the missing position of the specified data. Then, obtain the second vital sign feature data obtained by performing corresponding data filling processing on all the missing data positions in the first vital sign feature data. Finally, after the second vital sign feature data is generated, the second vital sign feature data is used as the vital sign feature data.
  • data filling processing is performed on the actual value of the vital sign feature data to realize the data completion processing of the vital sign feature data, and then the user can be processed based on the vital sign feature number after the data completion processing.
  • the prediction of the risk of heart failure effectively improves the accuracy of the subsequent prediction of the probability of occurrence of heart failure.
  • the method includes:
  • S500 Obtain the importance coefficients corresponding to each type of modal feature data according to the attention weight according to preset rules, where the modal feature data includes physiological signal feature data, vital sign feature data, and case text Characteristic data, laboratory examination characteristic data, and demographic characteristic data;
  • S501 Sort all the importance coefficients in descending order of numerical value to obtain a corresponding sorting result
  • the attention weight can be subsequently used to intelligently generate each type of modal feature data corresponding to The importance of the risk of heart failure predicts the outcome.
  • the above-mentioned fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the above-mentioned fusion feature data is generated by the above-mentioned attention module, and the attention weight is adjusted according to the above-mentioned attention weight.
  • the step of performing weighted summation processing for each fusion feature in the aforementioned fusion feature data to obtain the corresponding output result includes: first obtaining the importance coefficient of each type of modal feature data according to the aforementioned attention weight according to a preset rule, where
  • the aforementioned modal characteristic data includes physiological signal characteristic data, vital sign characteristic data, case text characteristic data, laboratory examination characteristic data, and demographic characteristic data.
  • the aforementioned preset rule may refer to obtaining the importance coefficient corresponding to each type of modal feature data by calculating the average value of all attention weights corresponding to each type of modal feature data.
  • a type of modal feature data and the importance result of the risk of heart failure can quickly screen out the high value that affects the risk of heart failure from all the modal feature data, that is, the target modal feature data with higher importance, and More attention resources can be devoted to the target modal feature data.
  • the attention of these irrelevant information can be reduced, and even some irrelevant information can be filtered out.
  • Information which can solve the problem of information overload and improve the generation efficiency and prediction accuracy of the subsequent prediction of the probability of occurrence of heart failure corresponding to the user.
  • step S500 includes:
  • S5000 Filter out the first attention weight corresponding to each of the physiological signal feature data, the second attention weight corresponding to each of the vital sign feature data, and each of the case feature data respectively.
  • S5001 Calculate the first average value of all the first attention weights, the second average value of all the second attention weights, the third average value of all the third attention weights, and all the first attention weights.
  • S5002 Use the first average value as the first importance coefficient of the physiological signal characteristic data relative to the risk of heart failure, and use the second average value as the vital sign characteristic data relative to the risk of heart failure.
  • the second importance coefficient, the third average value is used as the third importance coefficient of the case characteristic data relative to the risk of heart failure
  • the fourth average value is used as the laboratory examination characteristic data relative to the heart failure.
  • the fourth importance coefficient of the risk of occurrence of heart failure, and the fifth average value is used as the fifth importance coefficient of the demographic characteristic data relative to the risk of occurrence of heart failure.
  • the foregoing step of obtaining the importance coefficients corresponding to each type of modal feature data according to the preset rules according to the foregoing attention weight may specifically include: The first attention weight corresponding to the signal feature data, the second attention weight corresponding to each of the above-mentioned vital sign feature data, the third attention weight corresponding to each of the above-mentioned case feature data, and each of the above experiments The fourth attention weight corresponding to the laboratory examination feature data, and the fifth attention weight corresponding to each of the above-mentioned demographic feature data.
  • the first average of all the above-mentioned first attention weights calculates the first average of all the above-mentioned first attention weights, the second average of all the above-mentioned second attention weights, the third average of all the above-mentioned third attention weights, and all the above-mentioned fourth attention weights.
  • the fourth average, and the fifth average of all the above fifth attention weights are used as the first importance coefficient of the physiological signal characteristic data relative to the risk of heart failure
  • the second average value is used as the second importance coefficient of the vital sign characteristic data relative to the risk of heart failure.
  • the above-mentioned third average value is regarded as the third importance coefficient of the above-mentioned case characteristic data relative to the risk of heart failure
  • the above-mentioned fourth average value is regarded as the fourth importance coefficient of the above-mentioned laboratory examination characteristic data relative to the risk of heart failure
  • the above fifth average value as the fifth importance coefficient of the above demographic characteristic data relative to the risk of heart failure.
  • the method includes:
  • S601 Determine whether the predicted probability of occurrence of heart failure is greater than the risk threshold
  • the method includes: first obtaining the prediction Set the risk threshold.
  • the above-mentioned risk threshold is not specifically limited, and can be set according to actual needs, for example, it can be set to 0.8. Then determine whether the predicted probability of occurrence of heart failure is greater than the risk threshold.
  • the predicted probability of occurrence of heart failure is greater than the risk threshold, it is determined that the heart failure occurrence risk of the user is at a high risk level, and the high risk level represents that the heart failure occurrence risk of the user is at least twice the average risk. And if the predicted probability of occurrence of heart failure is not greater than the risk threshold, it is determined whether the predicted probability of occurrence of heart failure is within a first preset range.
  • the above-mentioned first preset range is not specifically limited, and can be set according to actual needs, for example, it can be set to 0.5-0.8. If the predicted probability of occurrence of heart failure is within the first preset range, it is determined that the risk of occurrence of heart failure of the user is at a medium risk level.
  • the medium risk level means that the user's heart failure risk is slightly higher than the average risk. If the predicted probability of occurrence of heart failure is not within the first preset range, it is determined that the risk of occurrence of heart failure of the user is at a low risk level.
  • the low risk level means that the user's heart failure risk is close to or lower than the average risk.
  • three colors of red, yellow, and green can be used to visually display the above-mentioned risk levels. Red represents high risk levels, yellow represents medium risk levels, and green represents low risk levels. This embodiment converts the predicted probability of occurrence of heart failure into the corresponding risk level, so that the user can intelligently understand the current risk of heart failure more intuitively, so that the corresponding prevention can be taken intelligently and quickly in the future. Treatment measures.
  • the method includes:
  • S610 When the user's heart failure occurrence risk is a high-risk level state or a medium-risk level state, generate early warning information, where the early warning information includes the predicted probability of the occurrence of heart failure and corresponding risk level information;
  • the above-mentioned step of inputting the above-mentioned output result into a preset classification module, and performing normalization processing on the above-mentioned output result through the above-mentioned classification module to obtain the corresponding heart failure risk prediction probability it includes: When the occurrence risk is a high-risk level state or a medium-risk level state, early warning information is generated, where the foregoing early warning information includes the predicted probability of occurrence of the heart failure and the corresponding risk level information. Then get advice related to heart failure prevention. Then obtain the above-mentioned user's identity information.
  • the above-mentioned warning information and the above-mentioned suggestion information are sent to the user terminal corresponding to the above-mentioned identity information.
  • the user-related early warning information and advice information it is beneficial for the user to understand the risk of his own heart failure in time, and to provide the user with corresponding heart failure prevention suggestions. Information to improve user experience.
  • the pathological data analysis method in the embodiment of the present application can also be applied to the blockchain field, such as storing the aforementioned data such as the predicted probability of occurrence of heart failure on the blockchain.
  • the blockchain By using the blockchain to store and manage the predicted probability of occurrence of heart failure, the security and non-tamperability of the predicted probability of occurrence of heart failure can be effectively guaranteed.
  • the above-mentioned blockchain is a new application mode of computer technology such as distributed data storage, point-to-point transmission, consensus mechanism, and encryption algorithm.
  • Blockchain essentially a decentralized database, is a series of data blocks associated with cryptographic methods. Each data block contains a batch of network transaction information for verification. The validity of the information (anti-counterfeiting) and the generation of the next block.
  • the blockchain can include the underlying platform of the blockchain, the platform product service layer, and the application service layer.
  • the underlying platform of the blockchain can include processing modules such as user management, basic services, smart contracts, and operation monitoring.
  • the user management module is responsible for the identity information management of all blockchain participants, including the maintenance of public and private key generation (account management), key management, and maintenance of the correspondence between the user’s real identity and the blockchain address (authority management), etc.
  • authorization supervise and audit certain real-identity transactions, and provide risk control rule configuration (risk control audit); basic service modules are deployed on all blockchain node devices to verify the validity of business requests, After completing the consensus on the valid request, it is recorded on the storage.
  • the basic service For a new business request, the basic service first performs interface adaptation analysis and authentication processing (interface adaptation), and then encrypts the business information through the consensus algorithm (consensus management), After encryption, it is completely and consistently transmitted to the shared ledger (network communication), and recorded and stored; the smart contract module is responsible for contract registration and issuance, contract triggering and contract execution.
  • interface adaptation interface adaptation
  • consensus algorithm consensus algorithm
  • the smart contract module is responsible for contract registration and issuance, contract triggering and contract execution.
  • the operation monitoring module is mainly responsible for the deployment of the product release process , Configuration modification, contract settings, cloud adaptation, and visual output of real-time status during product operation, such as: alarms, monitoring network conditions, monitoring node equipment health status, etc.
  • an embodiment of the present application also provides a heart failure risk prediction device, including:
  • Collection module 1, used to collect pathological data of users
  • the extraction module 2 is configured to perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, wherein the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
  • the first acquisition module 3 is configured to acquire structured characteristic data of the user related to the risk of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
  • the processing module 4 is configured to perform splicing processing on the designated feature data and the structured feature data to obtain merged feature data after the splicing process;
  • the first generating module 5 is configured to use the fusion feature data as the input of a preset attention module, and generate the attention weight corresponding to each fusion feature in the fusion feature data through the attention module, And performing weighted summation processing on each fusion feature in the fusion feature data according to the attention weight to obtain a corresponding output result;
  • the second generation module 6 is configured to input the output result into a preset classification module, and normalize the output result through the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  • the realization process of the functions and functions of the acquisition module, extraction module, first acquisition module, processing module, first generation module and second generation module in the above-mentioned heart failure risk prediction device is detailed in the above-mentioned pathological data.
  • the analysis method corresponds to the implementation process of steps S1 to S6, which will not be repeated here.
  • the aforementioned extraction module includes:
  • the first extraction sub-module is configured to use a convolutional neural network to perform feature extraction on the physiological signal data in the pathological data to obtain physiological signal feature data corresponding to the physiological signal data;
  • the second extraction sub-module is used for feature extraction of vital sign data in the pathological data by using a cyclic neural network to obtain corresponding vital sign feature data;
  • the third extraction sub-module is used to extract key features of the case text data in the pathological data by using Chinese natural language processing technology to obtain corresponding case text feature data.
  • the realization process of the functions and roles of the first extraction submodule, the second extraction submodule and the third extraction submodule in the above-mentioned heart failure risk prediction device are detailed in the corresponding steps in the above-mentioned pathological data analysis method.
  • the implementation process of S200 to S202 will not be repeated here.
  • the above-mentioned second extraction submodule includes:
  • An extraction unit configured to use the cyclic neural network to perform feature extraction on vital sign data in the pathological data to obtain first vital sign feature data
  • a judging unit for judging whether there is a missing value in the first vital sign feature data
  • the first acquiring unit is configured to, if there is a missing value in the first vital sign characteristic data, acquire the data missing position in the first vital sign characteristic data;
  • the second acquiring unit is configured to acquire the last feature observation value corresponding to the designated data missing position, and acquire the mean value of the first vital sign feature data, wherein the designated data missing position is the value of all the data missing positions Any data missing position;
  • the calculation unit is configured to call a preset calculation formula to calculate the designated filling value corresponding to the missing position of the designated data according to the last feature observation value and the average value; the filling unit is configured to use the designated filling value Performing data filling processing on the designated data missing position;
  • the third acquiring unit is configured to acquire the second vital sign characteristic data obtained after corresponding data filling processing is performed on all missing data positions in the first vital sign characteristic data;
  • the determining unit is configured to use the second vital sign characteristic data as the vital sign characteristic data.
  • the functions and functions of the extraction unit, the judgment unit, the first acquisition unit, the second acquisition unit, the calculation unit, the filling unit, the third acquisition unit, and the determination unit in the above-mentioned heart failure risk prediction device please refer to the implementation process of corresponding steps S2010 to S2017 in the above analysis method of pathological data, which will not be repeated here.
  • the aforementioned pathological data analysis device includes:
  • the second acquisition module is configured to acquire the importance coefficients corresponding to each type of modal feature data according to the attention weight according to preset rules, wherein the modal feature data includes physiological signal feature data and vital signs Feature data, case text feature data, laboratory examination feature data, and demographic feature data;
  • the sorting module is used for sorting all the importance coefficients in descending order of numerical value to obtain the corresponding sorting result
  • the third generation module is configured to generate the importance prediction report of each type of the modal characteristic data corresponding to the risk of occurrence of heart failure according to the sorting result;
  • the display module is used to display the importance prediction report.
  • the realization process of the functions and functions of the second acquisition module, the sorting module, the third generation module, and the display module in the above-mentioned pathological data analysis device is detailed in the corresponding steps S500 to S503 in the above-mentioned pathological data analysis method. The realization process of this will not be repeated here.
  • the above-mentioned second acquisition module includes:
  • the screening sub-module is used to screen out the first attention weight corresponding to each of the physiological signal feature data, the second attention weight corresponding to each of the vital sign feature data, and each of the cases A third attention weight corresponding to the characteristic data, a fourth attention weight corresponding to each of the laboratory examination characteristic data, and a fifth attention weight corresponding to each of the demographic characteristic data;
  • the calculation sub-module is used to calculate the first average value of all the first attention weights, the second average value of all the second attention weights, the third average value of all the third attention weights, A fourth average value of all the fourth attention weights, and a fifth average value of all the fifth attention weights;
  • the determining sub-module is configured to use the first average value as the first importance coefficient of the physiological signal characteristic data relative to the risk of heart failure, and use the second average value as the vital sign characteristic data relative to the heart failure.
  • the second importance coefficient of the risk of occurrence of heart failure, the third average value is used as the third importance coefficient of the case feature data relative to the risk of heart failure, and the fourth average value is used as the laboratory test feature
  • the fourth importance coefficient of the data relative to the risk of heart failure, and the fifth average value is used as the fifth importance coefficient of the demographic characteristic data relative to the risk of heart failure.
  • the functions and functions of the screening sub-module, the calculation sub-module, and the determination sub-module in the above-mentioned pathological data analysis device are detailed in the realization process of corresponding steps S5000 to S5002 in the above-mentioned pathological data analysis method. I won't repeat them here.
  • the aforementioned pathological data analysis device includes:
  • the third obtaining module is used to obtain the preset risk threshold
  • the first judgment module is used to judge whether the predicted probability of occurrence of heart failure is greater than the risk threshold
  • the first determination module is configured to determine that the risk of occurrence of heart failure of the user is a high risk level if the predicted probability of occurrence of heart failure is greater than the risk threshold;
  • the second judgment module is configured to judge whether the predicted probability of heart failure is within a first preset range if the predicted probability of occurrence of heart failure is not greater than the risk threshold;
  • the second determination module is configured to determine that the risk of occurrence of heart failure of the user is a medium risk level if the predicted probability of occurrence of heart failure is within a first preset range;
  • the third determining module is configured to determine that the heart failure risk of the user is a low risk level if the predicted probability of the heart failure risk is not within the first preset range.
  • the realization process of the functions and functions of the third acquisition module, the first judgment module, the first judgment module, the second judgment module, the second judgment module, and the third judgment module in the above analysis device for pathological data is specific
  • the implementation process of corresponding steps S600 to S605 in the above analysis method of pathological data which will not be repeated here.
  • the aforementioned pathological data analysis device includes:
  • the third generation module is used to generate early warning information when the user's heart failure risk is in a high-risk state or a medium-risk state, wherein the early warning information includes the predicted probability of the heart failure and the corresponding risk Grade information
  • the fourth acquisition module is used to acquire recommended information related to the prevention of heart failure.
  • the fifth obtaining module is used to obtain the identity information of the user
  • the sending module is configured to send the warning information and the suggestion information to the user terminal corresponding to the identity information according to the identity information.
  • the realization process of the functions and roles of the third generation module, the fourth acquisition module, the fifth acquisition module, and the sending module in the above analysis device for pathological data is detailed in the corresponding step S610 in the above analysis method for pathology data.
  • the implementation process to S613 will not be repeated here.
  • an embodiment of the present application also provides a computer device.
  • the computer device may be a server, and its internal structure may be as shown in FIG. 3.
  • the computer equipment includes a processor, a memory, a network interface, a display screen, an input device and a database connected by a system bus.
  • the processor designed for the computer equipment is used to provide computing and control capabilities.
  • the memory of the computer device includes a non-volatile storage medium and an internal memory.
  • the non-volatile storage medium stores an operating system, a computer program, and a database.
  • the internal memory provides an environment for the operation of the operating system and computer programs in the non-volatile storage medium.
  • the database of the computer equipment is used to store data such as designated feature data, structured feature data, fusion feature data, attention weight, output results, and predicted probability of occurrence of heart failure.
  • the network interface of the computer device is used to communicate with an external terminal through a network connection.
  • the display screen of the computer equipment is an indispensable image and text output device in the computer, which is used to convert digital signals into optical signals so that text and graphics can be displayed on the screen of the display screen.
  • the input device of the computer equipment is the main device for information exchange between the computer and the user or other equipment, and is used to transfer data, instructions, and certain flag information to the computer.
  • the computer program is executed by the processor to realize a pathological data analysis method.
  • the above-mentioned processor executes the steps of the above-mentioned pathological data analysis method:
  • the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
  • the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data
  • the fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight.
  • Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
  • the output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  • FIG. 3 is only a block diagram of a part of the structure related to the solution of the present application, and does not constitute a limitation on the devices and computer equipment to which the solution of the present application is applied.
  • An embodiment of the present application also provides a computer-readable storage medium.
  • the computer-readable storage medium may be non-volatile or volatile, and has a computer program stored thereon, which is realized when the computer program is executed by a processor.
  • the method for analyzing pathological data includes the following steps:
  • the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
  • the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data
  • the fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight.
  • Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
  • the output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  • the pathological data analysis method, device, computer equipment, and storage medium collect multiple modal characteristic data of users related to the risk of heart failure, and perform the analysis on the multiple modalities.
  • State feature data is spliced, and based on the attention module and classification module, the fusion feature data generated after the splicing process is analyzed and processed, so as to intelligently and accurately generate the predicted probability of the user's heart failure, and realize the risk of the user's heart failure. Accurate prediction of, effectively improve the processing efficiency of predicting the risk of heart failure of users.
  • Non-volatile memory may include read only memory (ROM), programmable ROM (PROM), electrically programmable ROM (EPROM), electrically erasable programmable ROM (EEPROM), or flash memory.
  • Volatile memory may include random access memory (RAM) or external cache memory.
  • RAM is available in many forms, such as static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), dual-rate SDRAM (SSRSDRAM), enhanced SDRAM (ESDRAM), synchronous Link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM), etc.

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Abstract

A pathological data analysis method and apparatus, and a computer device and a storage medium, relating to the field of digital healthcare. The method comprises: collecting pathological data of a user (S1); performing feature extraction on the pathological data, so as to obtain specified feature data related to the risk of heart failure occurrence (S2); acquiring structured feature data, related to the risk of heart failure occurrence, of the user (S3); performing splicing processing on the specified feature data and the structured feature data, so as to obtain fusion feature data after same is subjected to splicing processing (S4); taking the fusion feature data as an input of a preset attention module, generating, by means of the attention module, attention weights that are in one-to-one correspondence with each fusion feature of the fusion feature data, and performing, according to the attention weights, weighted sum processing on each fusion feature of the fusion feature data, so as to obtain corresponding output results (S5); and inputting the output results into a preset classification module, performing normalization processing on the output results by means of the classification module, and generating a predicted probability of heart failure occurrence corresponding to the user (S6). The method improves the processing efficiency and accuracy of predicting the risk of heart failure occurrence in a user.

Description

病理数据的分析方法、装置、计算机设备和存储介质Pathological data analysis method, device, computer equipment and storage medium
本申请要求于2020年9月9日提交中国专利局、申请号为2020109416268,发明名称为“病理数据的分析方法、装置、计算机设备和存储介质”的中国专利申请的优先权,其全部内容通过引用结合在本申请中。This application claims the priority of a Chinese patent application filed with the Chinese Patent Office on September 9, 2020, with the application number 2020109416268, and the invention title "Pathological data analysis methods, devices, computer equipment, and storage media". The entire content of the application is approved The reference is incorporated in this application.
技术领域Technical field
本申请涉及数字医疗技术领域,具体涉及一种病理数据的分析方法、装置、计算机设备和存储介质。This application relates to the field of digital medical technology, in particular to a pathological data analysis method, device, computer equipment and storage medium.
背景技术Background technique
心力衰竭(heart failure)简称心衰,是指由于心脏的收缩功能和(或)舒张功能发生障碍,不能将静脉回心血量充分排出心脏,导致静脉系统血液淤积,动脉系统血液灌注不足,从而引起心脏循环障碍症候群,此种障碍症候群集中表现为肺淤血、腔静脉淤血。心衰并不是一个独立的疾病,而是心脏疾病发展的终末阶段,当治疗不当会影响健康甚至会威胁到生命。但如果能够及早发现到存在较大的心衰发生风险并及时采取有效的预防和治疗措施,这将对改善患者预后及病死率具有重要意义。然而发明人意识到,现有对于心衰发生的高风险人群的筛查仍基于传统的经验判断,通常是由医生通过用户的临床症状来进行相应的心衰发生风险的预测,这样的心衰发生风险的预测方式需要花费大量的时间去搜集和分析临床数据,耗时耗力,且必须依赖医生的个人经验,而不同医生之间的经验水平往往差距较大,从而导致对于心衰发生的预测准确性较低。Heart failure (heart failure) referred to as heart failure, refers to the failure of the systolic and/or diastolic function of the heart, the inability to fully discharge the venous return blood volume out of the heart, resulting in blood stasis in the venous system and insufficient blood perfusion in the arterial system. Cardiac circulatory disorder syndrome, which is manifested in clusters of pulmonary congestion and vena cava congestion. Heart failure is not an independent disease, but the final stage of the development of heart disease. Improper treatment can affect health and even threaten life. However, if a greater risk of heart failure can be detected early and effective prevention and treatment measures can be taken in time, it will be of great significance to improve the prognosis and mortality of patients. However, the inventor realizes that the existing screening of people at high risk of heart failure is still based on traditional empirical judgments, and doctors usually use the user's clinical symptoms to predict the corresponding risk of heart failure. The method of predicting the risk of occurrence requires a lot of time to collect and analyze clinical data, time-consuming and labor-intensive, and must rely on the personal experience of the doctor, and the experience level of different doctors often differs greatly, which leads to the occurrence of heart failure. Forecast accuracy is low.
技术问题technical problem
本申请的主要目的为提供一种病理数据的分析方法、装置、计算机设备和存储介质,旨在解决现有的心衰发生风险的预测方式仍基于传统的经验判断,耗时耗力且预测准确性较低的技术问题。The main purpose of this application is to provide an analysis method, device, computer equipment and storage medium for pathological data, which aims to solve the problem that the existing prediction methods for the risk of heart failure are still based on traditional empirical judgments, which are time-consuming, labor-intensive and accurate. Technical problems with low sexuality.
技术解决方案Technical solutions
本申请提出一种病理数据的分析方法,所述方法包括步骤:This application proposes a method for analyzing pathological data. The method includes the steps:
采集用户的病理数据;Collect pathological data of users;
对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, wherein the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;Acquiring structured characteristic data of the user related to the risk of occurrence of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;Performing splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight. Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
本申请还提供一种心衰发生风险预测装置,包括:This application also provides a device for predicting the risk of heart failure, including:
采集模块,用于采集用户的病理数据;Collection module, used to collect pathological data of users;
提取模块,用于对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;The extraction module is used for feature extraction of the pathological data to obtain specified feature data related to the risk of heart failure, wherein the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
第一获取模块,用于获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;The first acquisition module is configured to acquire structured characteristic data of the user related to the risk of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
处理模块,用于对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;A processing module, configured to perform splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
第一生成模块,用于将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The first generation module is configured to use the fusion feature data as the input of the preset attention module, and generate the attention weight corresponding to each fusion feature in the fusion feature data through the attention module, and Performing weighted summation processing on each fusion feature in the fusion feature data according to the attention weight to obtain a corresponding output result;
第二生成模块,用于将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The second generation module is configured to input the output result into a preset classification module, and normalize the output result through the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
本申请还提供一种计算机设备,包括存储器和处理器,所述存储器中存储有计算机程序,所述处理器执行所述计算机程序时实现一种病理数据的分析方法,其中,所述病理数据的分析方法包括以下步骤:The present application also provides a computer device, including a memory and a processor, the memory stores a computer program, and the processor implements a pathological data analysis method when the computer program is executed, wherein the pathological data The analysis method includes the following steps:
采集用户的病理数据;Collect pathological data of users;
对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, wherein the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;Acquiring structured characteristic data of the user related to the risk of occurrence of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;Performing splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight. Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
本申请还提供一种计算机可读存储介质,其上存储有计算机程序,所述计算机程序被处理器执行时实现一种病理数据的分析方法,其中,所述病理数据的分析方法包括以下步骤:The present application also provides a computer-readable storage medium on which a computer program is stored, and when the computer program is executed by a processor, a method for analyzing pathological data is realized, wherein the method for analyzing pathological data includes the following steps:
采集用户的病理数据;Collect pathological data of users;
对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;Acquiring structured characteristic data of the user related to the risk of occurrence of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;Performing splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight. Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
有益效果Beneficial effect
本申请中提供的病理数据的分析方法、装置、计算机设备和存储介质,能够智能准确地生成用户的心衰发生预测概率,实现对于用户心衰发生风险的精准预测,有效地提高了预测用户心衰发生风险的处理效率。The pathological data analysis method, device, computer equipment and storage medium provided in this application can intelligently and accurately generate the prediction probability of the user’s heart failure, realize the accurate prediction of the user’s heart failure risk, and effectively improve the prediction of the user’s heart failure. The efficiency of handling the risk of failure.
附图说明Description of the drawings
图1是本申请一实施例的告警根因的定位方法的流程示意图;FIG. 1 is a schematic flowchart of a method for locating the root cause of an alarm according to an embodiment of the present application;
图2是本申请一实施例的告警根因的定位装置的结构示意图;FIG. 2 is a schematic structural diagram of an apparatus for locating the root cause of an alarm according to an embodiment of the present application;
图3是本申请一实施例的计算机设备的结构示意图。Fig. 3 is a schematic structural diagram of a computer device according to an embodiment of the present application.
本发明的最佳实施方式The best mode of the present invention
应当理解,此处所描述的具体实施例仅仅用于解释本申请,并不用于限定本申请。It should be understood that the specific embodiments described here are only used to explain the present application, and are not used to limit the present application.
本方案可应用于智慧城市中的数字医疗领域,从而推动智慧城市的建设。This solution can be applied to the digital medical field in smart cities, thereby promoting the construction of smart cities.
参照图1,本申请一实施例的病理数据的分析方法,包括:1, the pathological data analysis method of an embodiment of the present application includes:
S1:采集用户的病理数据;S1: Collect pathological data of users;
S2:对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;S2: Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
S3:获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;S3: Obtain structured characteristic data of the user related to the risk of heart failure, where the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
S4:对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;S4: Perform splicing processing on the designated feature data and the structured feature data to obtain merged feature data after the splicing process;
S5:将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;S5: The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is generated according to the attention Weight performs weighted summation processing on each fusion feature in the fusion feature data to obtain a corresponding output result;
S6:将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。S6: Input the output result to a preset classification module, and normalize the output result through the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
如上述步骤S1至S6所述,本方法实施例的执行主体为一种心衰发生风险预测装置。在实际应用中,上述心衰发生风险预测装置可以通过虚拟装置,例如软件代码实现,也可以通过写入或集成有相关执行代码的实体装置实现,且可以与用户通过键盘、鼠标、遥控器、触摸板或声控设备等方式进行人机交互。本实施例中的心衰发生风险预测装置能够智能准确地生成用户的心衰发生预测概率,实现对于用户心衰发生风险的精准预测,有效地提高了预测用户心衰发生风险的处理效率。具体地,首先采集用户的病理数据。其中,可以通过多个数据来源来采集用户在预设历史时间期间内的病理数据,对上述数据来源不作具体限定,例如可包括电子病历系统、用户的疾病拍摄或扫描文件,等等;以及对上述预设历史时间期间内不作具体限定,例如可为近两年。另外,上述病理数据至少可包括生理信号数据、生命体征数据与病例文本数据等数据。然后对上述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,上述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据。另外,对于不同模态的病理数据会对应采用不同的特征提取方式,具体的,可采用卷积神经网络提取出上述生理 信号特征数据,采用循环神经网络提取出上述生命体征特征数据,以及采用中文自然语言处理技术提取出病例文本特征数据。此外,上述生理信号特征数据可包括心电特征数据等;上述生命体征数据可包括血压特征数据、心率特征数据与呼吸率特征数据等;上述病例文本特征数据包括与高血压、糖尿病、抗高血压治疗、家族病史、婚姻状况等相关联的特征数据。并获取与心衰发生风险相关的上述用户的结构化特征数据,其中,上述结构化特征数据包括实验室检查特征数据与人口统计学特征数据,上述实验室检查特征数据可包括血常规,尿常规等特征数据,上述人口统计学特征数据可包括年龄、性别和疾病史等特征数据。另外,由于上述结构化特征数据中的实验室检查特征数据与人口统计学特征数据属于不随时间变化的信息,因此可以直接提取得到该结构化特征数据,而无需经过特征提取的处理操作。上述病理数据还可包括用户实验室检查特征数据与人口统计学特征数据,从而可以直接从上述病理数据中获取上述结构化特征数据。之后对上述指定特征数据与上述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据。其中,可利用阶段集成学习算法来实现对于上述指定特征数据与上述结构化特征数据之间的数据拼接处理。在得到了上述融合特征数据后,再将上述融合特征数据作为预设的注意力模块的输入,通过上述注意力模块生成与上述融合特征数据中每一个融合特征一一对应的注意力权重,并根据上述注意力权重对上述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果。其中,计算注意力权重的过程包括:先计算融合特征数据中每一个融合特征的注意力得分,再使用softmax函数对每一个注意力得分进行数值转换,生成每一个融合特征的注意力权重,该注意力权重是指每个融合特征受关注程度的权重,且所有的注意力权重之和为1。具体地,可先通过公式e k,j=relu(W ah j+b a)计算出融合特征数据中每一个融合特征的注意力得分,e k,j为注意力得分,W a与b a是模型的注意力层可学习的网络参数,h j为融合特征数据中的任意一个融合特征,relu为激活函数。在得到了注意力得分后,再通过公式
Figure PCTCN2020125152-appb-000001
计算出与融合特征数据中每一个融合特征对应的注意力权重,即通过使用softmax函数对每一个e k,j进行归一化计算处理,以向每一个融合特征赋予对应的注意力权重,并得到所有注意力权重之和为1的注意力分布。另外,可通过公式
Figure PCTCN2020125152-appb-000002
进行点乘处理,即根据注意力权重对融合特征数据中每一融合特征进行加权求和处理,生成与融合特征数据对应的Attention值,即上述输出结果。最后在得到了上述输出结果时候,将上述输出结果输入至预设的分类模块,通过上述分类模块对上述输出结果进行归一化处理,生成与上述用户对应的心衰发生预测概率。其中,可通过公式O τ=sigmoid(W cC+b c),对注意力模块的输出结果进行归一化处理以生成最终的心衰发生预测概率。O τ为心衰发生预测概率,且O τ的范围在数值0~1之间,W c与b c是分类模块可学习的网络参数,C为注意力模块的输出结果。本方案可应用于智慧城市中的数字医疗领域,从而推动智慧城市的建设。本申请通过采集与心衰发生风险相关的用户的多种模态特征数据,并对该多种模态特征数据进行拼接处理,并基于注意力模块与分类模块对拼接处理后生成的融合特征数据进行数据分析处理,从而能够智能准确地生成用户的心衰发生预测概率,实现对于用户心衰发生风险的精准预测,有效地提高了预测用户心衰发生风险的处理效率。
As described in the above steps S1 to S6, the execution subject of this method embodiment is a heart failure risk prediction device. In practical applications, the above-mentioned heart failure risk prediction device can be realized by a virtual device, such as software code, or by a physical device written or integrated with relevant execution codes, and can communicate with the user through a keyboard, mouse, remote control, Human-computer interaction is carried out by means of touchpad or voice control equipment. The heart failure risk prediction device in this embodiment can intelligently and accurately generate the user's heart failure prediction probability, realizes accurate prediction of the user's heart failure risk, and effectively improves the processing efficiency for predicting the user's heart failure risk. Specifically, first collect the pathological data of the user. Among them, multiple data sources can be used to collect the user's pathological data during the preset historical time period. The aforementioned data sources are not specifically limited. For example, they can include electronic medical record systems, user's disease shooting or scanning files, etc.; and The aforementioned preset historical time period is not specifically limited, and may be, for example, the past two years. In addition, the above-mentioned pathological data may include at least physiological signal data, vital signs data, case text data and other data. Then, feature extraction is performed on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data. In addition, different feature extraction methods will be used for pathological data of different modalities. Specifically, convolutional neural networks can be used to extract the above-mentioned physiological signal feature data, recurrent neural networks can be used to extract the above-mentioned vital sign feature data, and Chinese Natural language processing technology extracts case text feature data. In addition, the above-mentioned physiological signal characteristic data may include electrocardiographic characteristic data, etc.; the above-mentioned vital sign data may include blood pressure characteristic data, heart rate characteristic data, and respiratory rate characteristic data, etc.; Related characteristic data such as treatment, family medical history, marital status, etc. And obtain the structured characteristic data of the user related to the risk of heart failure, where the structured characteristic data includes laboratory test characteristic data and demographic characteristic data, and the laboratory test characteristic data may include blood routine and urine routine. The above-mentioned demographic characteristic data may include characteristic data such as age, gender, and disease history. In addition, because the laboratory test feature data and demographic feature data in the structured feature data are information that does not change with time, the structured feature data can be extracted directly without the need for feature extraction processing operations. The above-mentioned pathological data may also include user laboratory examination characteristic data and demographic characteristic data, so that the above-mentioned structured characteristic data can be directly obtained from the above-mentioned pathological data. Then, the specified feature data and the structured feature data are spliced to obtain the merged feature data after splicing. Among them, a staged integrated learning algorithm can be used to realize the data splicing process between the specified feature data and the structured feature data. After the fusion feature data is obtained, the fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated through the attention module, and Perform weighted summation processing on each fusion feature in the fusion feature data according to the above attention weight to obtain a corresponding output result. Among them, the process of calculating the attention weight includes: first calculating the attention score of each fusion feature in the fusion feature data, and then using the softmax function to perform numerical conversion on each attention score to generate the attention weight of each fusion feature. Attention weight refers to the weight of the attention degree of each fusion feature, and the sum of all attention weights is 1. Specifically, the attention score of each fusion feature in the fusion feature data can be calculated by the formula e k,j =relu(W a h j +b a ), e k,j are the attention scores, and W a and b a is the network parameters that can be learned by the attention layer of the model, h j is any fusion feature in the fusion feature data, and relu is the activation function. After getting the attention score, pass the formula
Figure PCTCN2020125152-appb-000001
Calculate the attention weight corresponding to each fusion feature in the fusion feature data, that is, use the softmax function to normalize each e k, j to assign the corresponding attention weight to each fusion feature, and Obtain the attention distribution with the sum of all attention weights being 1. In addition, the formula
Figure PCTCN2020125152-appb-000002
Perform dot multiplication processing, that is, perform weighted summation processing on each fusion feature in the fusion feature data according to the attention weight, and generate the Attention value corresponding to the fusion feature data, that is, the above output result. Finally, when the aforementioned output result is obtained, the aforementioned output result is input to a preset classification module, and the aforementioned output result is normalized by the aforementioned classification module to generate a predicted probability of occurrence of heart failure corresponding to the aforementioned user. Among them, the output result of the attention module can be normalized by the formula O τ =sigmoid(W c C+b c ) to generate the final predicted probability of occurrence of heart failure. O τ is the predicted probability of heart failure, and the range of O τ is between 0 and 1, W c and b c are network parameters that can be learned by the classification module, and C is the output result of the attention module. This solution can be applied to the digital medical field in smart cities, thereby promoting the construction of smart cities. This application collects multiple modal feature data of users related to the risk of heart failure, and performs splicing processing on the multiple modal feature data, and based on the attention module and the classification module on the fusion feature data generated after the splicing process Data analysis and processing can intelligently and accurately generate the user's heart failure prediction probability, realize the accurate prediction of the user's heart failure risk, and effectively improve the processing efficiency of predicting the user's heart failure risk.
进一步地,上述注意力模块为训练生成的心衰发生风险预测模型中的注意力网络,上述分类模块为上述心衰发生风险预测模型中的分类器,且该心衰发生风险预测模型还可包括用于进行特征提取的特征提取网络。具体的,特征提取网络,以心衰患者数据的病理数据作为输入,经过特征提取处理后输出与心衰发生风险对应的特征数据。注意力网络,以与心衰发生风险对应的患者的特征数据及,与心衰发生风险对应的患者的结构化特征数据拼接起来得到的融合特征数据作为输入,输出注意力权重,并将融合特征数据与对应的注意力权重进行加权求和处理,得到输出结果,即注意力值。分类器,将注意力网络输出的注意力值作为输入,对该注意力值进行归一化处理,输出分类结果。通过获取采集预设数量的患者的病理数据作为训练样本,并将该训练样本作为初始模型中的输入层,以上述训练样本对应的真值标签作为初始模型的输出层,对上述初始模型进行训练,获得对应的特征提取模块、注意力模块与分类模块,从而最终生成上述心衰发生风险预测模型。其中,上述心衰发生风险预测模型的训练生成过程可参照现有的模型训练生成方式,在此不再赘述。另外,上述特征提取模块对应上述特征提取网络,上述注意力模块对应上述注意力网络,上述分类模块对应上述分类器。且上述训练样本还包括与心衰发生风险对应的结构化特征数据。Further, the aforementioned attention module is an attention network in the heart failure risk prediction model generated by training, the classification module is a classifier in the heart failure risk prediction model, and the heart failure risk prediction model may further include Feature extraction network for feature extraction. Specifically, the feature extraction network takes pathological data of heart failure patient data as input, and outputs feature data corresponding to the risk of heart failure after feature extraction processing. The attention network uses the feature data of the patients corresponding to the risk of heart failure and the fusion feature data obtained by splicing the structured feature data of the patients corresponding to the risk of heart failure as input, outputs the attention weight, and integrates the features The data and the corresponding attention weight are weighted and summed to obtain the output result, which is the attention value. The classifier takes the attention value output by the attention network as input, normalizes the attention value, and outputs the classification result. Train the initial model by acquiring pathological data of a preset number of patients as a training sample, using the training sample as the input layer in the initial model, and using the truth label corresponding to the training sample as the output layer of the initial model , Obtain the corresponding feature extraction module, attention module and classification module, and finally generate the above-mentioned heart failure risk prediction model. Among them, the training and generation process of the above-mentioned heart failure risk prediction model can refer to the existing model training and generation methods, and will not be repeated here. In addition, the above-mentioned feature extraction module corresponds to the above-mentioned feature extraction network, the above-mentioned attention module corresponds to the above-mentioned attention network, and the above-mentioned classification module corresponds to the above-mentioned classifier. And the aforementioned training samples also include structured feature data corresponding to the risk of heart failure.
进一步地,本申请一实施例中,上述步骤S2,包括:Further, in an embodiment of the present application, the above step S2 includes:
S200:采用卷积神经网络对所述病理数据中的生理信号数据进行特征提取,得到与所述生理信号数据对应的生理信号特征数据;以及,S200: Perform feature extraction on the physiological signal data in the pathological data by using a convolutional neural network to obtain physiological signal feature data corresponding to the physiological signal data; and,
S201:采用循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特 征数据;以及,S201: Perform feature extraction on vital sign data in the pathological data by using a cyclic neural network to obtain corresponding vital sign feature data; and,
S202:采用中文自然语言处理技术对所述病理数据中的病例文本数据进行关键特征提取,得到对应的病例文本特征数据。S202: Use Chinese natural language processing technology to extract key features of the case text data in the pathology data to obtain corresponding case text feature data.
如上述步骤S200至S202所述,对于病理数据中不同模态的数据,会对应使用相应的深度神经网络来对进行对于不同模态数据的特征提取,以提高对于病理数据的特征提取的准确性。上述对上述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据的步骤具体可包括:采用卷积神经网络对上述病理数据中的生理信号数据进行特征提取,得到与上述生理信号数据对应的生理信号特征数据。其中,对于生理信号数据,包括心电数据。由于生理信号数据属于高密度采样的时序波形数据,可通过使用卷积神经网络对该生理信号数据进行提取特征,并输出对应的生理信号特征数据。具体的,P=CNN(ECG),ECG代表用户的生理信号数据,例如心电数据,CNN代表卷积神经网络,P代表输出的与生理信号数据的对应的生理信号特征数据。以及同时采用循环神经网络对上述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据。其中,上述生命体征数据可包括血压、体温、呼吸等数据,由于生命体征数据属于低密度采样的不连续的波形数据,可通过循环神经网络对上述生命体征数据进行特征提取,并输出对应的生命体征特征数据。循环神经网络能够有效地考虑数据之间的时序依赖关系。具体的,Q=RNN(waveform),waveform代表用户的生命体征数据,RNN代表循环神经网络,例如可以包括LSTM或者GRU网络结构,Q代表输出的与生命体征数据对应的生命体征特征数据。以及同时采用中文自然语言处理(NLP)技术对上述病理数据中的病例文本数据进行关键特征提取,得到对应的病例文本特征数据。其中,对于文本数据,可以采用先进的NLP技术,根据预设的关键字信息,如包括高血压、糖尿病、抗高血压治疗、家族病史与婚姻状况等等,通过Embedding和RNN结合的方法自动抽取患者关键特征。具体的,V=Embedding(word),R=RNN(V),word代表用户的病例文本数据,Embedding代表词嵌入技术的处理,RNN代表循环神经网络,例如可以包括LSTM或者GRU网络结构。举例地,通过对上述生理信号特征数据P、生命体征特征数据Q以及病例文本特征数据R进行拼接处理,可得到相应的融合特征数据为:S=[P,Q,R]。本实施例根据病理数据中不同模态数据的数据特性,会对应使用相应的深度神经网络来对进行对于不同模态数据的特征提取,进而能够准确快捷地从病理数据中提取出所需的指定特征数据,使得后续能够根据该指定特征数据来准确快捷地进行对于用户的心衰发生风险的预测。As described in the above steps S200 to S202, for the data of different modalities in the pathological data, corresponding deep neural networks will be used to extract the features of the different modal data to improve the accuracy of the feature extraction of the pathological data. . The step of extracting features from the pathological data to obtain specified feature data related to the risk of heart failure may specifically include: using a convolutional neural network to extract features from the physiological signal data in the pathological data to obtain the physiological signal data. Corresponding physiological signal characteristic data. Among them, the physiological signal data includes ECG data. Since the physiological signal data belongs to high-density sampling time-series waveform data, the characteristics of the physiological signal data can be extracted by using a convolutional neural network, and the corresponding physiological signal characteristic data can be output. Specifically, P=CNN (ECG), ECG represents the physiological signal data of the user, such as electrocardiogram data, CNN represents the convolutional neural network, and P represents the output physiological signal characteristic data corresponding to the physiological signal data. And at the same time, the recurrent neural network is used to extract the characteristics of the vital sign data in the above-mentioned pathological data to obtain the corresponding vital sign characteristic data. Among them, the above vital sign data may include blood pressure, body temperature, respiration and other data. Since the vital sign data belongs to low-density sampling of discontinuous waveform data, the above vital sign data can be feature extracted through a cyclic neural network, and the corresponding vital signs can be output. Physical characteristics data. Recurrent neural networks can effectively consider the timing dependence between data. Specifically, Q=RNN (waveform), waveform represents the vital sign data of the user, RNN represents cyclic neural network, which may include LSTM or GRU network structure, for example, and Q represents the output vital sign feature data corresponding to the vital sign data. And at the same time, Chinese natural language processing (NLP) technology is used to extract key features of the case text data in the above pathological data to obtain the corresponding case text feature data. Among them, for text data, advanced NLP technology can be used to automatically extract based on preset keyword information, such as hypertension, diabetes, anti-hypertensive treatment, family history and marital status, etc., through the combination of Embedding and RNN. Key patient characteristics. Specifically, V=Embedding(word), R=RNN(V), word represents the user's case text data, Embedding represents the processing of word embedding technology, and RNN represents cyclic neural network, which may include LSTM or GRU network structure, for example. For example, by splicing the above-mentioned physiological signal feature data P, vital sign feature data Q, and case text feature data R, the corresponding fusion feature data can be obtained as: S=[P,Q,R]. According to the data characteristics of the different modal data in the pathological data, this embodiment will use the corresponding deep neural network to extract the features of the different modal data, so as to accurately and quickly extract the required specifications from the pathological data. The characteristic data enables the subsequent accurate and quick prediction of the risk of the user's heart failure based on the designated characteristic data.
进一步地,本申请一实施例中,上述步骤S201,包括:Further, in an embodiment of the present application, the above step S201 includes:
S2010:采用所述循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到第一生命体征特征数据;S2010: Perform feature extraction on vital sign data in the pathological data by using the recurrent neural network to obtain first vital sign feature data;
S2011:判断所述第一生命体征特征数据中是否存在缺失值;S2011: Determine whether there are missing values in the first vital sign characteristic data;
S2012:若所述第一生命体征特征数据中存在缺失值,则获取所述第一生命体征特征数据中的数据缺失位置;S2012: If there is a missing value in the first vital sign characteristic data, obtain the data missing position in the first vital sign characteristic data;
S2013:获取与指定数据缺失位置对应的上次特征观测值,以及获取所述第一生命体征特征数据的均值,其中,所述指定数据缺失位置为所有所述数据缺失位置的任意一个数据缺失位置;S2013: Obtain the last characteristic observation value corresponding to the designated data missing position, and acquire the mean value of the first vital sign characteristic data, wherein the designated data missing position is any data missing position of all the data missing positions ;
S2014:根据所述上次特征观测值与所述均值,调用预设的计算公式计算出与所述指定数据缺失位置对应的指定填充值;S2015:使用所述指定填充值对所述指定数据缺失位置进行数据填充处理;S2014: According to the last feature observation value and the average value, call a preset calculation formula to calculate the designated filling value corresponding to the designated data missing position; S2015: Use the designated filling value to delete the designated data Position data filling processing;
S2016:获取对所述第一生命体征特征数据中所有的数据缺失位置进行对应的数据填充处理后得到的第二生命体征特征数据;S2016: Obtain second vital sign feature data obtained after performing corresponding data filling processing on all missing data positions in the first vital sign feature data;
S2017:将所述第二生命体征特征数据作为所述生命体征特征数据。S2017: Use the second vital sign feature data as the vital sign feature data.
如上述步骤S2010至S2017所述,在采用循环神经网络提取出生命体征特征数据后,后续还可对生命体征特征数据中出现的缺失数据进行填充处理,以实现对于生命体征特征数据的数据完善处理。具体地,上述采用循环神经网络对上述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据的步骤,包括:首先采用上述循环神经网络对上述病理数据中的生命体征数据进行特征提取,得到第一生命体征特征数据。然后判断上述第一生命体征特征数据中是否存在缺失值。如果上述第一生命体征特征数据中存在缺失值,则获取上述第一生命体征特征数据中的数据缺失位置。然后获取与指定数据缺失位置对应的上次特征观测值,以及获取上述第一生命体征特征数据的均值,其中,上述指定数据缺失位置为所有上述数据缺失位置的任意一个数据缺失位置。之后根据上述上次特征观测值与上述均值,调用预设的计算公式计算出与上述指定数据缺失位置对应的指定填充值。具体的,可通过计算公式
Figure PCTCN2020125152-appb-000003
计算出上述指定填充值,其中,
Figure PCTCN2020125152-appb-000004
是需要填充的缺失值,即上述指定填充值,
Figure PCTCN2020125152-appb-000005
为与上述指定数据缺失位置对应的上次特征观测值,x’ d为上述第一生命 体征特征数据的均值(也可称为经验均值),
Figure PCTCN2020125152-appb-000006
为掩码矩阵,表示当前的数据变量是否有被观测到,如果被观测到则值取1,如果未被观测到则值取0。举例地,如果在某个时刻,第d个数据变量被观测到,那么这个时刻这个变量等于这个观测值,而如果没有观测到,则表示为缺失数据或缺失值。
Figure PCTCN2020125152-appb-000007
为与指定数据缺失位置对应的指定时间衰减因子,可通过公式Υ t=exp(-max(0,W Υδ t+b Υ))来求取时间衰减因子,其中,Υ t为与循环神经网络对应的时间衰减因子,W Υ与b Υ为循环神经网络可学习的网络参数,δ t为数据缺失位置距离上次观测值之间的时间间隔,且Υ t最终会归一到数值0~1的范围内。另外,上述与指定数据缺失位置对应的指定填充值需要在上次特征观测值和均值之间平衡。通过加入时间衰减因子计算指定填充值时,如果指定数据缺失位置距离上次特征观测值越远,则均值的权重会更大一些;而如果指定数据缺失位置距离上次特征观测值比较近,那么上次特征观测值的权重会更大一些。在得到了上述指定填充值后,再使用上述指定填充值对上述指定数据缺失位置进行数据填充处理。之后获取对上述第一生命体征特征数据中所有的数据缺失位置进行对应的数据填充处理后得到的第二生命体征特征数据。最后在生成了上述第二生命体征特征数据后,再将上述第二生命体征特征数据作为上述生命体征特征数据。本实施例通过对生命体征特征数据中的确实值进行数据填充处理,实现了对于生命体征特征数据的数据完善处理,进而在后续能够基于经过数据完善处理后的生命体征特征数来进行对于用户的心衰发生风险的预测,有效地提高了后续生成的心衰发生预测概率的准确性。
As described in the above steps S2010 to S2017, after the vital sign feature data is extracted by the cyclic neural network, the missing data in the vital sign feature data can be filled in to complete the data processing of the vital sign feature data. . Specifically, the step of using the recurrent neural network to extract features from the vital sign data in the pathological data to obtain the corresponding vital sign feature data includes: first using the recurrent neural network to feature the vital sign data in the pathological data Extract and obtain the first vital sign feature data. Then it is judged whether there are missing values in the first vital sign feature data. If there is a missing value in the first vital sign feature data, the data missing position in the first vital sign feature data is acquired. Then, the last feature observation value corresponding to the designated data missing location is obtained, and the average value of the first vital sign feature data is obtained, where the specified data missing location is any data missing location of all the above data missing locations. Then, according to the above-mentioned last feature observation value and the above-mentioned average value, a preset calculation formula is called to calculate the designated filling value corresponding to the above-mentioned designated data missing position. Specifically, it can be calculated by the formula
Figure PCTCN2020125152-appb-000003
Calculate the above specified fill value, where,
Figure PCTCN2020125152-appb-000004
Is the missing value that needs to be filled, that is, the specified fill value above,
Figure PCTCN2020125152-appb-000005
To the last observed value characteristic corresponding to the position of the designated data deletion, x 'd is the mean of the data of the first feature vital signs (also referred to as average experience),
Figure PCTCN2020125152-appb-000006
It is a mask matrix, indicating whether the current data variable has been observed, if it is observed, the value is 1, and if it is not observed, the value is 0. For example, if at a certain moment, the d-th data variable is observed, then this variable is equal to the observed value at this moment, and if it is not observed, it is indicated as missing data or missing value.
Figure PCTCN2020125152-appb-000007
For the designated time attenuation factor corresponding to the designated data missing position, the time attenuation factor can be obtained by the formula Υ t = exp(-max(0, W Υ δ t + b Υ )), where Υ t is the relationship with the circulatory nerve The time decay factor corresponding to the network, W Υ and b Υ are network parameters that can be learned by the cyclic neural network, δ t is the time interval between the position of the missing data and the last observation, and Υ t will eventually be normalized to a value of 0~ Within the range of 1. In addition, the specified fill value corresponding to the missing position of the specified data needs to be balanced between the last feature observation value and the mean value. When calculating the specified fill value by adding the time attenuation factor, if the missing location of the specified data is farther from the last feature observation value, the weight of the mean will be greater; and if the specified data missing location is closer to the last feature observation value, then The weight of the last feature observation will be greater. After the specified filling value is obtained, the specified filling value is used to perform data filling processing on the missing position of the specified data. Then, obtain the second vital sign feature data obtained by performing corresponding data filling processing on all the missing data positions in the first vital sign feature data. Finally, after the second vital sign feature data is generated, the second vital sign feature data is used as the vital sign feature data. In this embodiment, data filling processing is performed on the actual value of the vital sign feature data to realize the data completion processing of the vital sign feature data, and then the user can be processed based on the vital sign feature number after the data completion processing. The prediction of the risk of heart failure effectively improves the accuracy of the subsequent prediction of the probability of occurrence of heart failure.
进一步地,本申请一实施例中,上述步骤S5之后,包括:Further, in an embodiment of the present application, after the above step S5, the method includes:
S500:根据所述注意力权重,按照预设规则获取与每一类模态特征数据分别对应的重要性系数,其中,所述模态特征数据包括生理信号特征数据、生命体征特征数据、病例文本特征数据、实验室检查特征数据以及人口统计学特征数据;S500: Obtain the importance coefficients corresponding to each type of modal feature data according to the attention weight according to preset rules, where the modal feature data includes physiological signal feature data, vital sign feature data, and case text Characteristic data, laboratory examination characteristic data, and demographic characteristic data;
S501:将所有所述重要性系数按照数值从大到小的顺序进行排序,得到对应的排序结果;S501: Sort all the importance coefficients in descending order of numerical value to obtain a corresponding sorting result;
S502:根据所述排序结果,生成每一类所述模态特征数据对应于心衰发生风险的重要性预测报告;S502: According to the sorting result, generate an importance prediction report for each type of the modal characteristic data corresponding to the risk of occurrence of heart failure;
S503:展示所述重要性预测报告。S503: Display the importance prediction report.
如上述步骤S500至S503所述,在生成了与融合特征数据中每一个融合特征一一对应的注意力权重后,后续可以根据该注意力权重来智能地生成每一类模态特征数据对应于心衰发生风险的重要性预测结果。具体地,上述将上述融合特征数据作为预设的注意力模块的输入,通过上述注意力模块生成与上述融合特征数据中每一个融合特征一一对应的注意力权重,并根据上述注意力权重对上述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果的步骤之后包括:首先根据上述注意力权重,按照预设规则获取每一类模态特征数据的重要性系数,其中,上述模态特征数据包括生理信号特征数据、生命体征特征数据、病例文本特征数据、实验室检查特征数据以及人口统计学特征数据。另外,上述预设规则可指通过计算每一类模态特征数据对应的所有注意力权重的平均值,来得到与每一类模态特征数据分别对应的重要性系数。在得到了上述重要性系数后,再将所有上述重要性系数按照数值从大到小的顺序进行排序,得到对应的排序结果。然后根据上述排序结果,生成每一类模态特征数据对应于心衰发生风险的重要性预测报告。最后在得到了上述重要性预测报告时,再展示上述重要性预测报告。本实施例在获得了与每一类模态特征数据分别对应的重要性系数后,通过使用该重要性系数对每一类模态特征数据进行重要性排序后,从而可以直观清楚地了解到每一类模态特征数据与心衰发生风险的重要性结果,进而能够从所有模态特征数据中快速筛选出影响心衰发生风险的高价值,即重要性较高的目标模态特征数据,并可对目标模态特征数据投入更多的注意力资源。另外,如果存在某些模态特征数据对于心衰发生风险的重要性程度极低(如重要性参数小于某一预设阈值),则可以降低地这些无关信息的关注度,甚至过滤掉一部分无关信息,从而可以解决信息过载问题,提高后续求取用户对应的心衰发生预测概率的生成效率和预测准确性。As described in the above steps S500 to S503, after the attention weight corresponding to each fusion feature in the fusion feature data is generated, the attention weight can be subsequently used to intelligently generate each type of modal feature data corresponding to The importance of the risk of heart failure predicts the outcome. Specifically, the above-mentioned fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the above-mentioned fusion feature data is generated by the above-mentioned attention module, and the attention weight is adjusted according to the above-mentioned attention weight. The step of performing weighted summation processing for each fusion feature in the aforementioned fusion feature data to obtain the corresponding output result includes: first obtaining the importance coefficient of each type of modal feature data according to the aforementioned attention weight according to a preset rule, where The aforementioned modal characteristic data includes physiological signal characteristic data, vital sign characteristic data, case text characteristic data, laboratory examination characteristic data, and demographic characteristic data. In addition, the aforementioned preset rule may refer to obtaining the importance coefficient corresponding to each type of modal feature data by calculating the average value of all attention weights corresponding to each type of modal feature data. After the above-mentioned importance coefficients are obtained, all the above-mentioned importance coefficients are sorted in descending order of numerical value to obtain the corresponding sorting result. Then, according to the above sorting results, a prediction report of the importance of each type of modal characteristic data corresponding to the risk of heart failure is generated. Finally, when the above-mentioned importance forecast report is obtained, the above-mentioned importance forecast report will be displayed. In this embodiment, after the importance coefficient corresponding to each type of modal feature data is obtained, the importance of each type of modal feature data is sorted by using the importance coefficient, so that each type of modal feature data can be intuitively and clearly understood. A type of modal feature data and the importance result of the risk of heart failure, and then can quickly screen out the high value that affects the risk of heart failure from all the modal feature data, that is, the target modal feature data with higher importance, and More attention resources can be devoted to the target modal feature data. In addition, if there are certain modal feature data that are extremely low in importance to the risk of heart failure (for example, the importance parameter is less than a preset threshold), the attention of these irrelevant information can be reduced, and even some irrelevant information can be filtered out. Information, which can solve the problem of information overload and improve the generation efficiency and prediction accuracy of the subsequent prediction of the probability of occurrence of heart failure corresponding to the user.
进一步地,本申请一实施例中,上述步骤S500,包括:Further, in an embodiment of the present application, the above step S500 includes:
S5000:筛选出与每一个所述生理信号特征数据分别对应的第一注意力权重、与每一个所述生命体征特征数据分别对应的第二注意力权重、与每一个所述病例特征数据分别对应的第三注意力权重、与每一个所述实验室检查特征数据分别对应的第四注意力权重,以及与每一个所述人口统计学特征数据分别对应的第五注意力权重;S5000: Filter out the first attention weight corresponding to each of the physiological signal feature data, the second attention weight corresponding to each of the vital sign feature data, and each of the case feature data respectively. The third attention weight of, the fourth attention weight corresponding to each of the laboratory examination characteristic data, and the fifth attention weight corresponding to each of the demographic characteristic data;
S5001:计算出所有所述第一注意力权重的第一平均值、所有所述第二注意力权重的第二平均值、所有所述第三注意力权重的第三平均值、所有所述第四注意力权重的第四平均值,以及所有所述第五注意力权重的第五平均值;S5001: Calculate the first average value of all the first attention weights, the second average value of all the second attention weights, the third average value of all the third attention weights, and all the first attention weights. The fourth average value of four attention weights, and the fifth average value of all the fifth attention weights;
S5002:将所述第一平均值作为所述生理信号特征数据相对于心衰发生风险的第一重要性系数,将所述第二平均值作为所述生命体征特征数据相对于心衰发生风险的第二重要性系数,将所述第三平均值作为所述病例特征数据相对于心衰发生风险的第三重要性系数,将所述第四平均值作为所述实验室检查 特征数据相对于心衰发生风险的第四重要性系数,以及将所述第五平均值作为所述人口统计学特征数据相对于心衰发生风险的第五重要性系数。S5002: Use the first average value as the first importance coefficient of the physiological signal characteristic data relative to the risk of heart failure, and use the second average value as the vital sign characteristic data relative to the risk of heart failure. The second importance coefficient, the third average value is used as the third importance coefficient of the case characteristic data relative to the risk of heart failure, and the fourth average value is used as the laboratory examination characteristic data relative to the heart failure. The fourth importance coefficient of the risk of occurrence of heart failure, and the fifth average value is used as the fifth importance coefficient of the demographic characteristic data relative to the risk of occurrence of heart failure.
如上述步骤S5000至S5002所述,上述根据上述注意力权重,按照预设规则获取与每一类模态特征数据分别对应的重要性系数的步骤,具体可包括:首先筛选出与每一个上述生理信号特征数据分别对应的第一注意力权重、与每一个上述生命体征特征数据分别对应的第二注意力权重、与每一个上述病例特征数据分别对应的第三注意力权重、与每一个上述实验室检查特征数据分别对应的第四注意力权重,以及与每一个上述人口统计学特征数据分别对应的第五注意力权重。然后计算出所有上述第一注意力权重的第一平均值、所有上述第二注意力权重的第二平均值、所有上述第三注意力权重的第三平均值、所有上述第四注意力权重的第四平均值,以及所有上述第五注意力权重的第五平均值。最后将上述第一平均值作为上述生理信号特征数据相对于心衰发生风险的第一重要性系数,将上述第二平均值作为上述生命体征特征数据相对于心衰发生风险的第二重要性系数,将上述第三平均值作为上述病例特征数据相对于心衰发生风险的第三重要性系数,将上述第四平均值作为上述实验室检查特征数据相对于心衰发生风险的第四重要性系数,以及将上述第五平均值作为上述人口统计学特征数据相对于心衰发生风险的第五重要性系数。本实施例通过计算每一类模态特征数据包含的所有的注意力权重的平均值,能够智能快速地计算出每一类模态特征数据分别对应的重要性系数,有利于后续根据该重要性参数来智能快速地得到每一类模态特征数据对应于心衰发生风险的重要性程度,并可根据该重要性程度来从所有模态特征数据中快速筛选出影响心衰发生风险的高价值,即重要性较高的目标模态特征数据,从而可以对目标模态特征数据投入更多的注意力资源。As described in the foregoing steps S5000 to S5002, the foregoing step of obtaining the importance coefficients corresponding to each type of modal feature data according to the preset rules according to the foregoing attention weight may specifically include: The first attention weight corresponding to the signal feature data, the second attention weight corresponding to each of the above-mentioned vital sign feature data, the third attention weight corresponding to each of the above-mentioned case feature data, and each of the above experiments The fourth attention weight corresponding to the laboratory examination feature data, and the fifth attention weight corresponding to each of the above-mentioned demographic feature data. Then calculate the first average of all the above-mentioned first attention weights, the second average of all the above-mentioned second attention weights, the third average of all the above-mentioned third attention weights, and all the above-mentioned fourth attention weights. The fourth average, and the fifth average of all the above fifth attention weights. Finally, the first average value is used as the first importance coefficient of the physiological signal characteristic data relative to the risk of heart failure, and the second average value is used as the second importance coefficient of the vital sign characteristic data relative to the risk of heart failure. , The above-mentioned third average value is regarded as the third importance coefficient of the above-mentioned case characteristic data relative to the risk of heart failure, and the above-mentioned fourth average value is regarded as the fourth importance coefficient of the above-mentioned laboratory examination characteristic data relative to the risk of heart failure , And the above fifth average value as the fifth importance coefficient of the above demographic characteristic data relative to the risk of heart failure. In this embodiment, by calculating the average value of all the attention weights contained in each type of modal feature data, the importance coefficients corresponding to each type of modal feature data can be calculated intelligently and quickly, which is beneficial to follow-up according to the importance. Parameters to intelligently and quickly obtain the degree of importance of each type of modal characteristic data corresponding to the risk of heart failure, and can quickly filter out the high value of the risk of heart failure from all the modal characteristic data according to the degree of importance , That is, the more important target modal feature data, so that more attention resources can be devoted to the target modal feature data.
进一步地,本申请一实施例中,上述步骤S6之后,包括:Further, in an embodiment of the present application, after the above step S6, the method includes:
S600:获取预设的风险阈值;S600: Obtain a preset risk threshold;
S601:判断所述心衰发生预测概率是否大于所述风险阈值;S601: Determine whether the predicted probability of occurrence of heart failure is greater than the risk threshold;
S602:若所述心衰发生预测概率大于所述风险阈值,则判定所述用户的心衰发生风险为高风险等级;S602: If the predicted probability of occurrence of heart failure is greater than the risk threshold, determine that the risk of occurrence of heart failure of the user is a high risk level;
S603:若所述心衰发生预测概率不大于所述风险阈值,判断所述心衰发生预测概率是否处于第一预设范围内;S603: If the predicted probability of occurrence of heart failure is not greater than the risk threshold, determine whether the predicted probability of occurrence of heart failure is within a first preset range;
S604:若所述心衰发生预测概率处于第一预设范围内,则判定所述用户的心衰发生风险为中风险等级;S604: If the predicted probability of occurrence of heart failure is within a first preset range, determine that the risk of occurrence of heart failure of the user is a medium risk level;
S605:若所述心衰风险预测概率不处于第一预设范围内,则判定所述用户的心衰发生风险为低风险等级。S605: If the heart failure risk prediction probability is not within the first preset range, determine that the heart failure risk of the user is a low risk level.
如上述步骤S600至S605所述,在生成了与用户对应的心衰发生预测概率后,后续可根据该心衰发生预测概率来智能地生成相应的风险等级。具体地,上述将上述输出结果输入至预设的分类模块,通过上述分类模块对上述输出结果进行归一化处理,得到与上述用户对应的心衰发生预测概率的步骤之后,包括:首先获取预设的风险阈值。其中,对于上述风险阈值不作具体限定,可根据实际需求进行设置,例如可设置为0.8。然后判断上述心衰发生预测概率是否大于上述风险阈值。如果上述心衰发生预测概率大于上述风险阈值,则判定上述用户的心衰发生风险处于高风险等级,高风险等级代表用户的心衰发生风险至少大于平均风险的2倍。而如果上述心衰发生预测概率不大于上述风险阈值,判断上述心衰发生预测概率是否处于第一预设范围内。其中,对于上述第一预设范围不作具体限定,可根据实际需求进行设置,例如可设置为0.5-0.8。如果上述心衰发生预测概率处于第一预设范围内,则判定上述用户的心衰发生风险处于中风险等级。中风险等级代表用户的心衰发生风险略高于平均风险。而如果上述心衰发生预测概率不处于第一预设范围内,则判定上述用户的心衰发生风险处于低风险等级。低风险等级代表用户的心衰发生风险接近或低于平均风险。另外,还可以采用红、黄、绿三种颜色对上述的风险等级进行可视化显示,红色代表高风险等级、黄色代表中风险等级、绿色代表低风险等级。本实施例通过将上述心衰发生预测概率转化为对应的风险等级,从而能够智能地让用户更加直观地了解到当前的心衰发生风险的风险程度,以便后续能够智能快捷地采取相对应的预防处理措施。As described in the above steps S600 to S605, after the predicted probability of occurrence of heart failure corresponding to the user is generated, the corresponding risk level can be intelligently generated subsequently according to the predicted probability of occurrence of heart failure. Specifically, after the step of inputting the output result to a preset classification module, and normalizing the output result through the classification module to obtain the predicted probability of occurrence of heart failure corresponding to the user, the method includes: first obtaining the prediction Set the risk threshold. Among them, the above-mentioned risk threshold is not specifically limited, and can be set according to actual needs, for example, it can be set to 0.8. Then determine whether the predicted probability of occurrence of heart failure is greater than the risk threshold. If the predicted probability of occurrence of heart failure is greater than the risk threshold, it is determined that the heart failure occurrence risk of the user is at a high risk level, and the high risk level represents that the heart failure occurrence risk of the user is at least twice the average risk. And if the predicted probability of occurrence of heart failure is not greater than the risk threshold, it is determined whether the predicted probability of occurrence of heart failure is within a first preset range. Among them, the above-mentioned first preset range is not specifically limited, and can be set according to actual needs, for example, it can be set to 0.5-0.8. If the predicted probability of occurrence of heart failure is within the first preset range, it is determined that the risk of occurrence of heart failure of the user is at a medium risk level. The medium risk level means that the user's heart failure risk is slightly higher than the average risk. If the predicted probability of occurrence of heart failure is not within the first preset range, it is determined that the risk of occurrence of heart failure of the user is at a low risk level. The low risk level means that the user's heart failure risk is close to or lower than the average risk. In addition, three colors of red, yellow, and green can be used to visually display the above-mentioned risk levels. Red represents high risk levels, yellow represents medium risk levels, and green represents low risk levels. This embodiment converts the predicted probability of occurrence of heart failure into the corresponding risk level, so that the user can intelligently understand the current risk of heart failure more intuitively, so that the corresponding prevention can be taken intelligently and quickly in the future. Treatment measures.
进一步地,本申请一实施例中,上述步骤S6之后,包括:Further, in an embodiment of the present application, after the above step S6, the method includes:
S610:当所述用户的心衰发生风险为高风险等级状态或中风险等级状态时,生成预警信息,其中,所述预警信息包括所述心衰发生预测概率以及对应的风险等级信息;S610: When the user's heart failure occurrence risk is a high-risk level state or a medium-risk level state, generate early warning information, where the early warning information includes the predicted probability of the occurrence of heart failure and corresponding risk level information;
S611:获取与心衰预防相关的建议信息;以及,S611: Obtain recommended information related to heart failure prevention; and,
S612:获取所述用户的身份信息;S612: Obtain the identity information of the user;
S613:根据所述身份信息,将所述预警信息与所述建议信息发送至与所述身份信息对应的用户终端。S613: According to the identity information, send the warning information and the advice information to the user terminal corresponding to the identity information.
如上述步骤S610至S613所述,在生成了与用户对应的心衰发生预测概率后,如果用户心衰发生风险处于高风险等级或中风险等级时,则后续可智能地为用户推送对应的预警信息与建议信息。具体地,上述将上述输出结果输入至预设的分类模块,通过上述分类模块对上述输出结果进行归一化处理,得到对应的心衰风险预测概率的步骤之后,包括:当上述用户的心衰发生风险为高风险等级状态或中风险等 级状态时,生成预警信息,其中,上述预警信息包括上述心衰发生预测概率以及对应的风险等级信息。然后获取与心衰预防相关的建议信息。之后获取上述用户的身份信息。最后在获取了上述身份信息后,再根据上述身份信息,将上述预警信息与上述建议信息发送至与上述身份信息对应的用户终端。本实施例通过智能地将与用户相关的预警信息及建议信息发送至用户相关的用户终端,有利于用户能够及时了解自身的心衰病发的风险,并为用户提供相应的心衰预防的建议信息,提高了用户使用体验。As described in the above steps S610 to S613, after the predicted probability of occurrence of heart failure corresponding to the user is generated, if the risk of occurrence of heart failure of the user is at a high risk level or a medium risk level, the corresponding early warning can be sent to the user intelligently. Information and advice. Specifically, after the above-mentioned step of inputting the above-mentioned output result into a preset classification module, and performing normalization processing on the above-mentioned output result through the above-mentioned classification module to obtain the corresponding heart failure risk prediction probability, it includes: When the occurrence risk is a high-risk level state or a medium-risk level state, early warning information is generated, where the foregoing early warning information includes the predicted probability of occurrence of the heart failure and the corresponding risk level information. Then get advice related to heart failure prevention. Then obtain the above-mentioned user's identity information. Finally, after obtaining the above-mentioned identity information, according to the above-mentioned identity information, the above-mentioned warning information and the above-mentioned suggestion information are sent to the user terminal corresponding to the above-mentioned identity information. In this embodiment, by intelligently sending the user-related early warning information and advice information to the user-related user terminal, it is beneficial for the user to understand the risk of his own heart failure in time, and to provide the user with corresponding heart failure prevention suggestions. Information to improve user experience.
本申请实施例中的病理数据的分析方法还可以应用于区块链领域,如将上述心衰发生预测概率等数据存储于区块链上。通过使用区块链来对上述心衰发生预测概率进行存储和管理,能够有效地保证上述心衰发生预测概率的安全性与不可篡改性。The pathological data analysis method in the embodiment of the present application can also be applied to the blockchain field, such as storing the aforementioned data such as the predicted probability of occurrence of heart failure on the blockchain. By using the blockchain to store and manage the predicted probability of occurrence of heart failure, the security and non-tamperability of the predicted probability of occurrence of heart failure can be effectively guaranteed.
上述区块链是分布式数据存储、点对点传输、共识机制、加密算法等计算机技术的新型应用模式。区块链(Blockchain),本质上是一个去中心化的数据库,是一串使用密码学方法相关联产生的数据块,每一个数据块中包含了一批次网络交易的信息,用于验证其信息的有效性(防伪)和生成下一个区块。区块链可以包括区块链底层平台、平台产品服务层以及应用服务层等。The above-mentioned blockchain is a new application mode of computer technology such as distributed data storage, point-to-point transmission, consensus mechanism, and encryption algorithm. Blockchain, essentially a decentralized database, is a series of data blocks associated with cryptographic methods. Each data block contains a batch of network transaction information for verification. The validity of the information (anti-counterfeiting) and the generation of the next block. The blockchain can include the underlying platform of the blockchain, the platform product service layer, and the application service layer.
区块链底层平台可以包括用户管理、基础服务、智能合约以及运营监控等处理模块。其中,用户管理模块负责所有区块链参与者的身份信息管理,包括维护公私钥生成(账户管理)、密钥管理以及用户真实身份和区块链地址对应关系维护(权限管理)等,并且在授权的情况下,监管和审计某些真实身份的交易情况,提供风险控制的规则配置(风控审计);基础服务模块部署在所有区块链节点设备上,用来验证业务请求的有效性,并对有效请求完成共识后记录到存储上,对于一个新的业务请求,基础服务先对接口适配解析和鉴权处理(接口适配),然后通过共识算法将业务信息加密(共识管理),在加密之后完整一致的传输至共享账本上(网络通信),并进行记录存储;智能合约模块负责合约的注册发行以及合约触发和合约执行,开发人员可以通过某种编程语言定义合约逻辑,发布到区块链上(合约注册),根据合约条款的逻辑,调用密钥或者其它的事件触发执行,完成合约逻辑,同时还提供对合约升级注销的功能;运营监控模块主要负责产品发布过程中的部署、配置的修改、合约设置、云适配以及产品运行中的实时状态的可视化输出,例如:告警、监控网络情况、监控节点设备健康状态等。The underlying platform of the blockchain can include processing modules such as user management, basic services, smart contracts, and operation monitoring. Among them, the user management module is responsible for the identity information management of all blockchain participants, including the maintenance of public and private key generation (account management), key management, and maintenance of the correspondence between the user’s real identity and the blockchain address (authority management), etc. In the case of authorization, supervise and audit certain real-identity transactions, and provide risk control rule configuration (risk control audit); basic service modules are deployed on all blockchain node devices to verify the validity of business requests, After completing the consensus on the valid request, it is recorded on the storage. For a new business request, the basic service first performs interface adaptation analysis and authentication processing (interface adaptation), and then encrypts the business information through the consensus algorithm (consensus management), After encryption, it is completely and consistently transmitted to the shared ledger (network communication), and recorded and stored; the smart contract module is responsible for contract registration and issuance, contract triggering and contract execution. Developers can define the contract logic through a certain programming language and publish it to On the blockchain (contract registration), according to the logic of the contract terms, call keys or other events to trigger execution, complete the contract logic, and also provide the function of contract upgrade and cancellation; the operation monitoring module is mainly responsible for the deployment of the product release process , Configuration modification, contract settings, cloud adaptation, and visual output of real-time status during product operation, such as: alarms, monitoring network conditions, monitoring node equipment health status, etc.
参照图2,本申请一实施例中还提供了一种心衰发生风险预测装置,包括:2, an embodiment of the present application also provides a heart failure risk prediction device, including:
采集模块1,用于采集用户的病理数据; Collection module 1, used to collect pathological data of users;
提取模块2,用于对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;The extraction module 2 is configured to perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, wherein the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
第一获取模块3,用于获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;The first acquisition module 3 is configured to acquire structured characteristic data of the user related to the risk of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
处理模块4,用于对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;The processing module 4 is configured to perform splicing processing on the designated feature data and the structured feature data to obtain merged feature data after the splicing process;
第一生成模块5,用于将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The first generating module 5 is configured to use the fusion feature data as the input of a preset attention module, and generate the attention weight corresponding to each fusion feature in the fusion feature data through the attention module, And performing weighted summation processing on each fusion feature in the fusion feature data according to the attention weight to obtain a corresponding output result;
第二生成模块6,用于将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The second generation module 6 is configured to input the output result into a preset classification module, and normalize the output result through the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
本实施例中,上述心衰发生风险预测装置中的采集模块、提取模块、第一获取模块、处理模块、第一生成模块与第二生成模块的功能和作用的实现过程具体详见上述病理数据的分析方法中对应步骤S1至S6的实现过程,在此不再赘述。In this embodiment, the realization process of the functions and functions of the acquisition module, extraction module, first acquisition module, processing module, first generation module and second generation module in the above-mentioned heart failure risk prediction device is detailed in the above-mentioned pathological data. The analysis method corresponds to the implementation process of steps S1 to S6, which will not be repeated here.
进一步地,本申请一实施例中,上述提取模块,包括:Further, in an embodiment of the present application, the aforementioned extraction module includes:
第一提取子模块,用于采用卷积神经网络对所述病理数据中的生理信号数据进行特征提取,得到与所述生理信号数据对应的生理信号特征数据;以及,The first extraction sub-module is configured to use a convolutional neural network to perform feature extraction on the physiological signal data in the pathological data to obtain physiological signal feature data corresponding to the physiological signal data; and,
第二提取子模块,用于采用循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据;以及,The second extraction sub-module is used for feature extraction of vital sign data in the pathological data by using a cyclic neural network to obtain corresponding vital sign feature data; and,
第三提取子模块,用于采用中文自然语言处理技术对所述病理数据中的病例文本数据进行关键特征提取,得到对应的病例文本特征数据。The third extraction sub-module is used to extract key features of the case text data in the pathological data by using Chinese natural language processing technology to obtain corresponding case text feature data.
本实施例中,上述心衰发生风险预测装置中的第一提取子模块、第二提取子模块与第三提取子模块的功能和作用的实现过程具体详见上述病理数据的分析方法中对应步骤S200至S202的实现过程,在此不再赘述。In this embodiment, the realization process of the functions and roles of the first extraction submodule, the second extraction submodule and the third extraction submodule in the above-mentioned heart failure risk prediction device are detailed in the corresponding steps in the above-mentioned pathological data analysis method. The implementation process of S200 to S202 will not be repeated here.
进一步地,本申请一实施例中,上述第二提取子模块,包括:Further, in an embodiment of the present application, the above-mentioned second extraction submodule includes:
提取单元,用于采用所述循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到第一生命体征特征数据;An extraction unit, configured to use the cyclic neural network to perform feature extraction on vital sign data in the pathological data to obtain first vital sign feature data;
判断单元,用于判断所述第一生命体征特征数据中是否存在缺失值;A judging unit for judging whether there is a missing value in the first vital sign feature data;
第一获取单元,用于若所述第一生命体征特征数据中存在缺失值,则获取所述第一生命体征特征数据中的数据缺失位置;The first acquiring unit is configured to, if there is a missing value in the first vital sign characteristic data, acquire the data missing position in the first vital sign characteristic data;
第二获取单元,用于获取与指定数据缺失位置对应的上次特征观测值,以及获取所述第一生命体征特征数据的均值,其中,所述指定数据缺失位置为所有所述数据缺失位置的任意一个数据缺失位置;The second acquiring unit is configured to acquire the last feature observation value corresponding to the designated data missing position, and acquire the mean value of the first vital sign feature data, wherein the designated data missing position is the value of all the data missing positions Any data missing position;
计算单元,用于根据所述上次特征观测值与所述均值,调用预设的计算公式计算出与所述指定数据缺失位置对应的指定填充值;填充单元,用于使用所述指定填充值对所述指定数据缺失位置进行数据填充处理;The calculation unit is configured to call a preset calculation formula to calculate the designated filling value corresponding to the missing position of the designated data according to the last feature observation value and the average value; the filling unit is configured to use the designated filling value Performing data filling processing on the designated data missing position;
第三获取单元,用于获取对所述第一生命体征特征数据中所有的数据缺失位置进行对应的数据填充处理后得到的第二生命体征特征数据;The third acquiring unit is configured to acquire the second vital sign characteristic data obtained after corresponding data filling processing is performed on all missing data positions in the first vital sign characteristic data;
确定单元,用于将所述第二生命体征特征数据作为所述生命体征特征数据。The determining unit is configured to use the second vital sign characteristic data as the vital sign characteristic data.
本实施例中,上述心衰发生风险预测装置中的提取单元、判断单元、第一获取单元、第二获取单元、计算单元、填充单元、第三获取单元与确定单元的功能和作用的实现过程具体详见上述病理数据的分析方法中对应步骤S2010至S2017的实现过程,在此不再赘述。In this embodiment, the functions and functions of the extraction unit, the judgment unit, the first acquisition unit, the second acquisition unit, the calculation unit, the filling unit, the third acquisition unit, and the determination unit in the above-mentioned heart failure risk prediction device For details, please refer to the implementation process of corresponding steps S2010 to S2017 in the above analysis method of pathological data, which will not be repeated here.
进一步地,本申请一实施例中,上述病理数据的分析装置,包括:Further, in an embodiment of the present application, the aforementioned pathological data analysis device includes:
第二获取模块,用于根据所述注意力权重,按照预设规则获取与每一类模态特征数据分别对应的重要性系数,其中,所述模态特征数据包括生理信号特征数据、生命体征特征数据、病例文本特征数据、实验室检查特征数据以及人口统计学特征数据;The second acquisition module is configured to acquire the importance coefficients corresponding to each type of modal feature data according to the attention weight according to preset rules, wherein the modal feature data includes physiological signal feature data and vital signs Feature data, case text feature data, laboratory examination feature data, and demographic feature data;
排序模块,用于将所有所述重要性系数按照数值从大到小的顺序进行排序,得到对应的排序结果;The sorting module is used for sorting all the importance coefficients in descending order of numerical value to obtain the corresponding sorting result;
第三生成模块,用于根据所述排序结果,生成每一类所述模态特征数据对应于心衰发生风险的重要性预测报告;The third generation module is configured to generate the importance prediction report of each type of the modal characteristic data corresponding to the risk of occurrence of heart failure according to the sorting result;
展示模块,用于展示所述重要性预测报告。The display module is used to display the importance prediction report.
本实施例中,上述病理数据的分析装置中的第二获取模块、排序模块、第三生成模块与展示模块的功能和作用的实现过程具体详见上述病理数据的分析方法中对应步骤S500至S503的实现过程,在此不再赘述。In this embodiment, the realization process of the functions and functions of the second acquisition module, the sorting module, the third generation module, and the display module in the above-mentioned pathological data analysis device is detailed in the corresponding steps S500 to S503 in the above-mentioned pathological data analysis method. The realization process of this will not be repeated here.
进一步地,本申请一实施例中,上述第二获取模块,包括:Further, in an embodiment of the present application, the above-mentioned second acquisition module includes:
筛选子模块,用于筛选出与每一个所述生理信号特征数据分别对应的第一注意力权重、与每一个所述生命体征特征数据分别对应的第二注意力权重、与每一个所述病例特征数据分别对应的第三注意力权重、与每一个所述实验室检查特征数据分别对应的第四注意力权重,以及与每一个所述人口统计学特征数据分别对应的第五注意力权重;The screening sub-module is used to screen out the first attention weight corresponding to each of the physiological signal feature data, the second attention weight corresponding to each of the vital sign feature data, and each of the cases A third attention weight corresponding to the characteristic data, a fourth attention weight corresponding to each of the laboratory examination characteristic data, and a fifth attention weight corresponding to each of the demographic characteristic data;
计算子模块,用于计算出所有所述第一注意力权重的第一平均值、所有所述第二注意力权重的第二平均值、所有所述第三注意力权重的第三平均值、所有所述第四注意力权重的第四平均值,以及所有所述第五注意力权重的第五平均值;The calculation sub-module is used to calculate the first average value of all the first attention weights, the second average value of all the second attention weights, the third average value of all the third attention weights, A fourth average value of all the fourth attention weights, and a fifth average value of all the fifth attention weights;
确定子模块,用于将所述第一平均值作为所述生理信号特征数据相对于心衰发生风险的第一重要性系数,将所述第二平均值作为所述生命体征特征数据相对于心衰发生风险的第二重要性系数,将所述第三平均值作为所述病例特征数据相对于心衰发生风险的第三重要性系数,将所述第四平均值作为所述实验室检查特征数据相对于心衰发生风险的第四重要性系数,以及将所述第五平均值作为所述人口统计学特征数据相对于心衰发生风险的第五重要性系数。The determining sub-module is configured to use the first average value as the first importance coefficient of the physiological signal characteristic data relative to the risk of heart failure, and use the second average value as the vital sign characteristic data relative to the heart failure. The second importance coefficient of the risk of occurrence of heart failure, the third average value is used as the third importance coefficient of the case feature data relative to the risk of heart failure, and the fourth average value is used as the laboratory test feature The fourth importance coefficient of the data relative to the risk of heart failure, and the fifth average value is used as the fifth importance coefficient of the demographic characteristic data relative to the risk of heart failure.
本实施例中,上述病理数据的分析装置中的筛选子模块、计算子模块与确定子模块的功能和作用的实现过程具体详见上述病理数据的分析方法中对应步骤S5000至S5002的实现过程,在此不再赘述。In this embodiment, the functions and functions of the screening sub-module, the calculation sub-module, and the determination sub-module in the above-mentioned pathological data analysis device are detailed in the realization process of corresponding steps S5000 to S5002 in the above-mentioned pathological data analysis method. I won't repeat them here.
进一步地,本申请一实施例中,上述病理数据的分析装置,包括:Further, in an embodiment of the present application, the aforementioned pathological data analysis device includes:
第三获取模块,用于获取预设的风险阈值;The third obtaining module is used to obtain the preset risk threshold;
第一判断模块,用于判断所述心衰发生预测概率是否大于所述风险阈值;The first judgment module is used to judge whether the predicted probability of occurrence of heart failure is greater than the risk threshold;
第一判定模块,用于若所述心衰发生预测概率大于所述风险阈值,则判定所述用户的心衰发生风险为高风险等级;The first determination module is configured to determine that the risk of occurrence of heart failure of the user is a high risk level if the predicted probability of occurrence of heart failure is greater than the risk threshold;
第二判断模块,用于若所述心衰发生预测概率不大于所述风险阈值,判断所述心衰发生预测概率是否处于第一预设范围内;The second judgment module is configured to judge whether the predicted probability of heart failure is within a first preset range if the predicted probability of occurrence of heart failure is not greater than the risk threshold;
第二判定模块,用于若所述心衰发生预测概率处于第一预设范围内,则判定所述用户的心衰发生风险为中风险等级;The second determination module is configured to determine that the risk of occurrence of heart failure of the user is a medium risk level if the predicted probability of occurrence of heart failure is within a first preset range;
第三判定模块,用于若所述心衰风险预测概率不处于第一预设范围内,则判定所述用户的心衰发生风险为低风险等级。The third determining module is configured to determine that the heart failure risk of the user is a low risk level if the predicted probability of the heart failure risk is not within the first preset range.
本实施例中,上述病理数据的分析装置中的第三获取模块、第一判断模块、第一判定模块、第二判断模块、第二判定模块与第三判定模块的功能和作用的实现过程具体详见上述病理数据的分析方法中对应步骤S600至S605的实现过程,在此不再赘述。In this embodiment, the realization process of the functions and functions of the third acquisition module, the first judgment module, the first judgment module, the second judgment module, the second judgment module, and the third judgment module in the above analysis device for pathological data is specific For details, refer to the implementation process of corresponding steps S600 to S605 in the above analysis method of pathological data, which will not be repeated here.
进一步地,本申请一实施例中,上述病理数据的分析装置,包括:Further, in an embodiment of the present application, the aforementioned pathological data analysis device includes:
第三生成模块,用于当所述用户的心衰发生风险为高风险等级状态或中风险等级状态时,生成预警信息,其中,所述预警信息包括所述心衰发生预测概率以及对应的风险等级信息;The third generation module is used to generate early warning information when the user's heart failure risk is in a high-risk state or a medium-risk state, wherein the early warning information includes the predicted probability of the heart failure and the corresponding risk Grade information
第四获取模块,用于获取与心衰预防相关的建议信息;以及,The fourth acquisition module is used to acquire recommended information related to the prevention of heart failure; and,
第五获取模块,用于获取所述用户的身份信息;The fifth obtaining module is used to obtain the identity information of the user;
发送模块,用于根据所述身份信息,将所述预警信息与所述建议信息发送至与所述身份信息对应的用户终端。The sending module is configured to send the warning information and the suggestion information to the user terminal corresponding to the identity information according to the identity information.
本实施例中,上述病理数据的分析装置中的第三生成模块、第四获取模块、第五获取模块与发送模块的功能和作用的实现过程具体详见上述病理数据的分析方法中对应步骤S610至S613的实现过程,在此不再赘述。In this embodiment, the realization process of the functions and roles of the third generation module, the fourth acquisition module, the fifth acquisition module, and the sending module in the above analysis device for pathological data is detailed in the corresponding step S610 in the above analysis method for pathology data. The implementation process to S613 will not be repeated here.
参照图3,本申请实施例中还提供一种计算机设备,该计算机设备可以是服务器,其内部结构可以如图3所示。该计算机设备包括通过系统总线连接的处理器、存储器、网络接口、显示屏、输入装置和数据库。其中,该计算机设备设计的处理器用于提供计算和控制能力。该计算机设备的存储器包括非易失性存储介质、内存储器。该非易失性存储介质存储有操作系统、计算机程序和数据库。该内存储器为非易失性存储介质中的操作系统和计算机程序的运行提供环境。该计算机设备的数据库用于存储指定特征数据、结构化特征数据、融合特征数据、注意力权重、输出结果以及心衰发生预测概率等数据。该计算机设备的网络接口用于与外部的终端通过网络连接通信。该计算机设备的显示屏是计算机中必不可少的一种图文输出设备,用于将数字信号转换为光信号,使文字与图形在显示屏的屏幕上显示出来。该计算机设备的输入装置是计算机与用户或其他设备之间进行信息交换的主要装置,用于把数据、指令及某些标志信息等输送到计算机中去。该计算机程序被处理器执行时以实现一种病理数据的分析方法。Referring to FIG. 3, an embodiment of the present application also provides a computer device. The computer device may be a server, and its internal structure may be as shown in FIG. 3. The computer equipment includes a processor, a memory, a network interface, a display screen, an input device and a database connected by a system bus. Among them, the processor designed for the computer equipment is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system, a computer program, and a database. The internal memory provides an environment for the operation of the operating system and computer programs in the non-volatile storage medium. The database of the computer equipment is used to store data such as designated feature data, structured feature data, fusion feature data, attention weight, output results, and predicted probability of occurrence of heart failure. The network interface of the computer device is used to communicate with an external terminal through a network connection. The display screen of the computer equipment is an indispensable image and text output device in the computer, which is used to convert digital signals into optical signals so that text and graphics can be displayed on the screen of the display screen. The input device of the computer equipment is the main device for information exchange between the computer and the user or other equipment, and is used to transfer data, instructions, and certain flag information to the computer. The computer program is executed by the processor to realize a pathological data analysis method.
上述处理器执行上述病理数据的分析方法的步骤:The above-mentioned processor executes the steps of the above-mentioned pathological data analysis method:
采集用户的病理数据;Collect pathological data of users;
对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;Acquiring structured characteristic data of the user related to the risk of occurrence of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;Performing splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight. Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
本领域技术人员可以理解,图3中示出的结构,仅仅是与本申请方案相关的部分结构的框图,并不构成对本申请方案所应用于其上的装置、计算机设备的限定。Those skilled in the art can understand that the structure shown in FIG. 3 is only a block diagram of a part of the structure related to the solution of the present application, and does not constitute a limitation on the devices and computer equipment to which the solution of the present application is applied.
本申请一实施例还提供一种计算机可读存储介质,所述计算机可读存储介质可以是非易失性,也可以是易失性,其上存储有计算机程序,计算机程序被处理器执行时实现上述任一个示例性实施例所示出的病理数据的分析方法,所述病理数据的分析方法包括以下步骤:An embodiment of the present application also provides a computer-readable storage medium. The computer-readable storage medium may be non-volatile or volatile, and has a computer program stored thereon, which is realized when the computer program is executed by a processor. In the method for analyzing pathological data shown in any of the above exemplary embodiments, the method for analyzing pathological data includes the following steps:
采集用户的病理数据;Collect pathological data of users;
对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;Acquiring structured characteristic data of the user related to the risk of occurrence of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;Performing splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight. Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
综上所述,本申请实施例中提供的病理数据的分析方法、装置、计算机设备和存储介质,通过采集与心衰发生风险相关的用户的多种模态特征数据,并对该多种模态特征数据进行拼接处理,并基于注意力模块与分类模块对拼接处理后生成的融合特征数据进行数据分析处理,从而能够智能准确地生成用户的心衰发生预测概率,实现对于用户心衰发生风险的精准预测,有效地提高了预测用户心衰发生风险的处理效率。In summary, the pathological data analysis method, device, computer equipment, and storage medium provided in the embodiments of the present application collect multiple modal characteristic data of users related to the risk of heart failure, and perform the analysis on the multiple modalities. State feature data is spliced, and based on the attention module and classification module, the fusion feature data generated after the splicing process is analyzed and processed, so as to intelligently and accurately generate the predicted probability of the user's heart failure, and realize the risk of the user's heart failure. Accurate prediction of, effectively improve the processing efficiency of predicting the risk of heart failure of users.
本领域普通技术人员可以理解实现上述实施例方法中的全部或部分流程,是可以通过计算机程序来指令相关的硬件来完成,所述的计算机程序可存储与一非易失性计算机可读取存储介质中,该计算机程序在执行时,可包括如上述各方法的实施例的流程。其中,本申请所提供的和实施例中所使用的对存储器、存储、数据库或其它介质的任何引用,均可包括非易失性和/或易失性存储器。非易失性存储器可以包括只读存储器(ROM)、可编程ROM(PROM)、电可编程ROM(EPROM)、电可擦除可编程ROM(EEPROM)或闪存。易失性存储器可包括随机存取存储器(RAM)或者外部高速缓冲存储器。作为说明而非局限,RAM通过多种形式可得,诸如静态RAM(SRAM)、动态RAM(DRAM)、同步DRAM(SDRAM)、双速据率SDRAM(SSRSDRAM)、增强型SDRAM(ESDRAM)、同步链路(Synchlink)DRAM(SLDRAM)、存储器总线(Rambus)直接RAM(RDRAM)、直接存储器总线动态RAM(DRDRAM)、以及存储器总线动态RAM(RDRAM)等。A person of ordinary skill in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be implemented by instructing relevant hardware through a computer program. The computer program can be stored and a non-volatile computer readable storage. In the medium, when the computer program is executed, it may include the processes of the above-mentioned method embodiments. Wherein, any reference to memory, storage, database or other media provided in this application and used in the embodiments may include non-volatile and/or volatile memory. Non-volatile memory may include read only memory (ROM), programmable ROM (PROM), electrically programmable ROM (EPROM), electrically erasable programmable ROM (EEPROM), or flash memory. Volatile memory may include random access memory (RAM) or external cache memory. As an illustration and not a limitation, RAM is available in many forms, such as static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), dual-rate SDRAM (SSRSDRAM), enhanced SDRAM (ESDRAM), synchronous Link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM), etc.
以上所述仅为本申请的优选实施例,并非因此限制本申请的专利范围,凡是利用本申请说明书及附图内容所作的等效结构或等效流程变换,或直接或间接运用在其他相关的技术领域,均同理包括在本申请的专利保护范围内。The above are only the preferred embodiments of this application, and do not limit the scope of this application. Any equivalent structure or equivalent process transformation made using the content of the specification and drawings of this application, or directly or indirectly applied to other related The technical field is equally included in the scope of patent protection of this application.

Claims (20)

  1. 一种病理数据的分析方法,其中,包括:A method for analyzing pathological data, including:
    采集用户的病理数据;Collect pathological data of users;
    对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
    获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;Acquiring structured characteristic data of the user related to the risk of occurrence of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
    对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;Performing splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
    将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight. Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
    将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  2. 根据权利要求1所述的病理数据的分析方法,其中,所述对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据的步骤,包括:The method for analyzing pathological data according to claim 1, wherein the feature extraction is performed on the pathological data to obtain designated characteristic data related to the risk of heart failure, wherein the designated characteristic data includes physiological signal characteristic data The steps of vital signs feature data and case text feature data include:
    采用卷积神经网络对所述病理数据中的生理信号数据进行特征提取,得到与所述生理信号数据对应的生理信号特征数据;以及,Using a convolutional neural network to perform feature extraction on the physiological signal data in the pathological data to obtain physiological signal feature data corresponding to the physiological signal data; and,
    采用循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据;以及,Perform feature extraction on vital sign data in the pathological data by using a recurrent neural network to obtain corresponding vital sign feature data; and,
    采用中文自然语言处理技术对所述病理数据中的病例文本数据进行关键特征提取,得到对应的病例文本特征数据。Using Chinese natural language processing technology to extract key features from the case text data in the pathological data, to obtain corresponding case text feature data.
  3. 根据权利要求2所述的病理数据的分析方法,其中,所述采用循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据的步骤,包括:The method for analyzing pathological data according to claim 2, wherein the step of using a cyclic neural network to perform feature extraction on vital sign data in the pathological data to obtain corresponding vital sign feature data comprises:
    采用所述循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到第一生命体征特征数据;Using the recurrent neural network to perform feature extraction on vital sign data in the pathological data to obtain first vital sign feature data;
    判断所述第一生命体征特征数据中是否存在缺失值;Judging whether there are missing values in the first vital sign feature data;
    若所述第一生命体征特征数据中存在缺失值,则获取所述第一生命体征特征数据中的数据缺失位置;If there is a missing value in the first vital sign characteristic data, acquiring the data missing position in the first vital sign characteristic data;
    获取与指定数据缺失位置对应的上次特征观测值,以及获取所述第一生命体征特征数据的均值,其中,所述指定数据缺失位置为所有所述数据缺失位置的任意一个数据缺失位置;Acquiring the last characteristic observation value corresponding to the designated data missing position, and acquiring the mean value of the first vital sign characteristic data, wherein the designated data missing position is any data missing position of all the data missing positions;
    根据所述上次特征观测值与所述均值,调用预设的计算公式计算出与所述指定数据缺失位置对应的指定填充值;使用所述指定填充值对所述指定数据缺 失位置进行数据填充处理;According to the last feature observation value and the average value, call a preset calculation formula to calculate a designated filling value corresponding to the designated data missing position; use the designated filling value to perform data filling on the designated data missing position deal with;
    获取对所述第一生命体征特征数据中所有的数据缺失位置进行对应的数据填充处理后得到的第二生命体征特征数据;Acquiring second vital sign feature data obtained after performing corresponding data filling processing on all missing positions in the first vital sign feature data;
    将所述第二生命体征特征数据作为所述生命体征特征数据。Use the second vital sign characteristic data as the vital sign characteristic data.
  4. 根据权利要求1所述的病理数据的分析方法,其中,所述将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果的步骤之后,包括:The method for analyzing pathological data according to claim 1, wherein the fusion feature data is used as the input of a preset attention module, and each fusion of the fusion feature data is generated by the attention module The feature has one-to-one correspondence with attention weights, and performing weighted summation processing on each fused feature in the fused feature data according to the attention weight to obtain the corresponding output result, including:
    根据所述注意力权重,按照预设规则获取与每一类模态特征数据分别对应的重要性系数,其中,所述模态特征数据包括生理信号特征数据、生命体征特征数据、病例文本特征数据、实验室检查特征数据以及人口统计学特征数据;According to the attention weight, the importance coefficient corresponding to each type of modal feature data is obtained according to preset rules, wherein the modal feature data includes physiological signal feature data, vital sign feature data, and case text feature data , Laboratory examination characteristic data and demographic characteristic data;
    将所有所述重要性系数按照数值从大到小的顺序进行排序,得到对应的排序结果;Sort all the importance coefficients in descending order of numerical value to obtain the corresponding sorting result;
    根据所述排序结果,生成每一类所述模态特征数据对应于心衰发生风险的重要性预测报告;According to the sorting result, generating the importance prediction report of each type of the modal characteristic data corresponding to the risk of occurrence of heart failure;
    展示所述重要性预测报告。Show the importance forecast report.
  5. 根据权利要求4所述的病理数据的分析方法,其中,所述根据所述注意力权重,按照预设规则获取与每一类模态特征数据分别对应的重要性系数,其中,所述模态特征数据包括生理信号特征数据、生命体征特征数据、病例文本特征数据、实验室检查特征数据以及人口统计学特征数据的步骤,包括:The method for analyzing pathological data according to claim 4, wherein the importance coefficient corresponding to each type of modal characteristic data is obtained according to the attention weight according to a preset rule, wherein the modal The characteristic data includes the steps of physiological signal characteristic data, vital sign characteristic data, case text characteristic data, laboratory examination characteristic data and demographic characteristic data, including:
    筛选出与每一个所述生理信号特征数据分别对应的第一注意力权重、与每一个所述生命体征特征数据分别对应的第二注意力权重、与每一个所述病例特征数据分别对应的第三注意力权重、与每一个所述实验室检查特征数据分别对应的第四注意力权重,以及与每一个所述人口统计学特征数据分别对应的第五注意力权重;The first attention weight corresponding to each of the physiological signal feature data, the second attention weight corresponding to each of the vital signs feature data, and the first attention weight corresponding to each of the case feature data are screened out. Three attention weights, a fourth attention weight corresponding to each of the laboratory examination characteristic data, and a fifth attention weight corresponding to each of the demographic characteristic data;
    计算出所有所述第一注意力权重的第一平均值、所有所述第二注意力权重的第二平均值、所有所述第三注意力权重的第三平均值、所有所述第四注意力权重的第四平均值,以及所有所述第五注意力权重的第五平均值;Calculate the first average value of all the first attention weights, the second average value of all the second attention weights, the third average value of all the third attention weights, and all the fourth attention weights. The fourth average value of the force weights, and the fifth average value of all the fifth attention weights;
    将所述第一平均值作为所述生理信号特征数据相对于心衰发生风险的第一重要性系数,将所述第二平均值作为所述生命体征特征数据相对于心衰发生风险的第二重要性系数,将所述第三平均值作为所述病例特征数据相对于心衰发生风险的第三重要性系数,将所述第四平均值作为所述实验室检查特征数据相对于心衰发生风险的第四重要性系数,以及将所述第五平均值作为所述人口统计学特征数据相对于心衰发生风险的第五重要性系数。The first average value is used as the first importance coefficient of the physiological signal characteristic data relative to the risk of heart failure, and the second average value is used as the second importance coefficient of the vital sign characteristic data relative to the risk of heart failure. Importance coefficient, the third average value is used as the third importance coefficient of the case characteristic data relative to the risk of heart failure, and the fourth average value is used as the laboratory examination characteristic data relative to the occurrence of heart failure The fourth importance coefficient of the risk, and the fifth average value is used as the fifth importance coefficient of the demographic characteristic data relative to the risk of heart failure.
  6. 根据权利要求1所述的病理数据的分析方法,其中,所述将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,得到与所述用户对应的心衰发生预测概率的步骤之后,包括:The method for analyzing pathological data according to claim 1, wherein the output result is input to a preset classification module, and the output result is normalized by the classification module to obtain the After the user's corresponding steps of predicting the probability of occurrence of heart failure, include:
    获取预设的风险阈值;Obtain the preset risk threshold;
    判断所述心衰发生预测概率是否大于所述风险阈值;Judging whether the predicted probability of occurrence of heart failure is greater than the risk threshold;
    若所述心衰发生预测概率大于所述风险阈值,则判定所述用户的心衰发生风险为高风险等级;If the predicted probability of occurrence of heart failure is greater than the risk threshold, determining that the risk of occurrence of heart failure of the user is a high risk level;
    若所述心衰发生预测概率不大于所述风险阈值,判断所述心衰发生预测概率是否处于第一预设范围内;If the predicted probability of occurrence of heart failure is not greater than the risk threshold, determining whether the predicted probability of occurrence of heart failure is within a first preset range;
    若所述心衰发生预测概率处于第一预设范围内,则判定所述用户的心衰发生风险为中风险等级;If the predicted probability of occurrence of heart failure is within the first preset range, determining that the risk of occurrence of heart failure of the user is a medium risk level;
    若所述心衰风险预测概率不处于第一预设范围内,则判定所述用户的心衰发生风险为低风险等级。If the heart failure risk prediction probability is not within the first preset range, it is determined that the heart failure risk of the user is a low risk level.
  7. 根据权利要求6所述的病理数据的分析方法,其中,所述将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,得到对应的心衰风险预测概率的步骤之后,包括:The method for analyzing pathological data according to claim 6, wherein the output result is input to a preset classification module, and the output result is normalized by the classification module to obtain the corresponding heart After the steps of predicting the probability of failure risk, include:
    当所述用户的心衰发生风险为高风险等级状态或中风险等级状态时,生成预警信息,其中,所述预警信息包括所述心衰发生预测概率以及对应的风险等级信息;When the user's heart failure occurrence risk is a high-risk level state or a medium-risk level state, generating early warning information, where the early warning information includes the predicted probability of the occurrence of heart failure and corresponding risk level information;
    获取与心衰预防相关的建议信息;以及,Obtain advice related to heart failure prevention; and,
    获取所述用户的身份信息;Obtaining the identity information of the user;
    根据所述身份信息,将所述预警信息与所述建议信息发送至与所述身份信息对应的用户终端。According to the identity information, the warning information and the suggestion information are sent to the user terminal corresponding to the identity information.
  8. 一种心衰发生风险预测装置,其中,包括:A device for predicting the risk of heart failure, which includes:
    采集模块,用于采集用户的病理数据;Collection module, used to collect pathological data of users;
    提取模块,用于对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;The extraction module is used for feature extraction of the pathological data to obtain specified feature data related to the risk of heart failure, wherein the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
    第一获取模块,用于获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;The first acquisition module is configured to acquire structured characteristic data of the user related to the risk of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
    处理模块,用于对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;A processing module, configured to perform splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
    第一生成模块,用于将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The first generation module is configured to use the fusion feature data as the input of the preset attention module, and generate the attention weight corresponding to each fusion feature in the fusion feature data through the attention module, and Performing weighted summation processing on each fusion feature in the fusion feature data according to the attention weight to obtain a corresponding output result;
    第二生成模块,用于将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The second generation module is configured to input the output result into a preset classification module, and normalize the output result through the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  9. 一种计算机设备,包括存储器和处理器,所述存储器中存储有计算机程序,其中,所述处理器执行所述计算机程序时实现一种病理数据的分析方法:A computer device includes a memory and a processor, and a computer program is stored in the memory, wherein the processor implements a pathological data analysis method when the computer program is executed by the processor:
    其中,所述病理数据的分析方法包括:Wherein, the analysis method of the pathological data includes:
    采集用户的病理数据;Collect pathological data of users;
    对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
    获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;Acquiring structured characteristic data of the user related to the risk of occurrence of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
    对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;Performing splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
    将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight. Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
    将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  10. 根据权利要求9所述的计算机设备,其中,所述对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据的步骤,包括:The computer device according to claim 9, wherein the characteristic extraction of the pathological data is performed to obtain designated characteristic data related to the risk of occurrence of heart failure, wherein the designated characteristic data includes physiological signal characteristic data and vital signs The steps of feature data and case text feature data include:
    采用卷积神经网络对所述病理数据中的生理信号数据进行特征提取,得到与所述生理信号数据对应的生理信号特征数据;以及,Using a convolutional neural network to perform feature extraction on the physiological signal data in the pathological data to obtain physiological signal feature data corresponding to the physiological signal data; and,
    采用循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据;以及,Perform feature extraction on vital sign data in the pathological data by using a recurrent neural network to obtain corresponding vital sign feature data; and,
    采用中文自然语言处理技术对所述病理数据中的病例文本数据进行关键特征提取,得到对应的病例文本特征数据。Using Chinese natural language processing technology to extract key features from the case text data in the pathological data, to obtain corresponding case text feature data.
  11. 根据权利要求10所述的计算机设备,其中,所述采用循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据的步骤,包括:The computer device according to claim 10, wherein the step of using a cyclic neural network to extract features of vital signs data in the pathological data to obtain corresponding feature data of vital signs comprises:
    采用所述循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到第一生命体征特征数据;Using the recurrent neural network to perform feature extraction on vital sign data in the pathological data to obtain first vital sign feature data;
    判断所述第一生命体征特征数据中是否存在缺失值;Judging whether there are missing values in the first vital sign feature data;
    若所述第一生命体征特征数据中存在缺失值,则获取所述第一生命体征特征数据中的数据缺失位置;If there is a missing value in the first vital sign characteristic data, acquiring the data missing position in the first vital sign characteristic data;
    获取与指定数据缺失位置对应的上次特征观测值,以及获取所述第一生命体征特征数据的均值,其中,所述指定数据缺失位置为所有所述数据缺失位置的任意一个数据缺失位置;Acquiring the last characteristic observation value corresponding to the designated data missing position, and acquiring the mean value of the first vital sign characteristic data, wherein the designated data missing position is any data missing position of all the data missing positions;
    根据所述上次特征观测值与所述均值,调用预设的计算公式计算出与所述指定数据缺失位置对应的指定填充值;使用所述指定填充值对所述指定数据缺失位置进行数据填充处理;According to the last feature observation value and the average value, call a preset calculation formula to calculate a designated filling value corresponding to the designated data missing position; use the designated filling value to perform data filling on the designated data missing position deal with;
    获取对所述第一生命体征特征数据中所有的数据缺失位置进行对应的数 据填充处理后得到的第二生命体征特征数据;Acquiring second vital sign feature data obtained after performing corresponding data filling processing on all missing positions in the first vital sign feature data;
    将所述第二生命体征特征数据作为所述生命体征特征数据。Use the second vital sign characteristic data as the vital sign characteristic data.
  12. 根据权利要求9所述的计算机设备,其中,所述将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果的步骤之后,包括:The computer device according to claim 9, wherein the fusion feature data is used as the input of a preset attention module, and each fusion feature in the fusion feature data is generated by the attention module one by one. Corresponding attention weight, and performing weighted summation processing on each fusion feature in the fusion feature data according to the attention weight to obtain the corresponding output result, including:
    根据所述注意力权重,按照预设规则获取与每一类模态特征数据分别对应的重要性系数,其中,所述模态特征数据包括生理信号特征数据、生命体征特征数据、病例文本特征数据、实验室检查特征数据以及人口统计学特征数据;According to the attention weight, the importance coefficient corresponding to each type of modal feature data is obtained according to preset rules, wherein the modal feature data includes physiological signal feature data, vital sign feature data, and case text feature data , Laboratory examination characteristic data and demographic characteristic data;
    将所有所述重要性系数按照数值从大到小的顺序进行排序,得到对应的排序结果;Sort all the importance coefficients in descending order of numerical value to obtain the corresponding sorting result;
    根据所述排序结果,生成每一类所述模态特征数据对应于心衰发生风险的重要性预测报告;According to the sorting result, generating the importance prediction report of each type of the modal characteristic data corresponding to the risk of occurrence of heart failure;
    展示所述重要性预测报告。Show the importance forecast report.
  13. 根据权利要求12所述的计算机设备,其中,所述根据所述注意力权重,按照预设规则获取与每一类模态特征数据分别对应的重要性系数,其中,所述模态特征数据包括生理信号特征数据、生命体征特征数据、病例文本特征数据、实验室检查特征数据以及人口统计学特征数据的步骤,包括:The computer device according to claim 12, wherein the importance coefficient corresponding to each type of modal characteristic data is obtained according to the attention weight according to a preset rule, wherein the modal characteristic data includes The steps of physiological signal characteristic data, vital signs characteristic data, case text characteristic data, laboratory examination characteristic data, and demographic characteristic data include:
    筛选出与每一个所述生理信号特征数据分别对应的第一注意力权重、与每一个所述生命体征特征数据分别对应的第二注意力权重、与每一个所述病例特征数据分别对应的第三注意力权重、与每一个所述实验室检查特征数据分别对应的第四注意力权重,以及与每一个所述人口统计学特征数据分别对应的第五注意力权重;The first attention weight corresponding to each of the physiological signal feature data, the second attention weight corresponding to each of the vital sign feature data, and the first attention weight corresponding to each of the case feature data are screened out. Three attention weights, a fourth attention weight corresponding to each of the laboratory examination characteristic data, and a fifth attention weight corresponding to each of the demographic characteristic data;
    计算出所有所述第一注意力权重的第一平均值、所有所述第二注意力权重的第二平均值、所有所述第三注意力权重的第三平均值、所有所述第四注意力权重的第四平均值,以及所有所述第五注意力权重的第五平均值;Calculate the first average value of all the first attention weights, the second average value of all the second attention weights, the third average value of all the third attention weights, and all the fourth attention weights. The fourth average value of the force weights, and the fifth average value of all the fifth attention weights;
    将所述第一平均值作为所述生理信号特征数据相对于心衰发生风险的第一重要性系数,将所述第二平均值作为所述生命体征特征数据相对于心衰发生风险的第二重要性系数,将所述第三平均值作为所述病例特征数据相对于心衰发生风险的第三重要性系数,将所述第四平均值作为所述实验室检查特征数据相对于心衰发生风险的第四重要性系数,以及将所述第五平均值作为所述人口统计学特征数据相对于心衰发生风险的第五重要性系数。The first average value is used as the first importance coefficient of the physiological signal characteristic data relative to the risk of heart failure, and the second average value is used as the second vital sign characteristic data relative to the risk of heart failure. Importance coefficient, the third average value is used as the third importance coefficient of the case characteristic data relative to the risk of heart failure, and the fourth average value is used as the laboratory examination characteristic data relative to the occurrence of heart failure The fourth importance coefficient of the risk, and the fifth average value is used as the fifth importance coefficient of the demographic characteristic data relative to the risk of heart failure.
  14. 根据权利要求9所述的计算机设备,其中,所述将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,得到与所述用户对应的心衰发生预测概率的步骤之后,包括:9. The computer device according to claim 9, wherein the output result is input to a preset classification module, and the output result is normalized by the classification module to obtain the corresponding After the steps of predicting the probability of occurrence of heart failure, include:
    获取预设的风险阈值;Obtain the preset risk threshold;
    判断所述心衰发生预测概率是否大于所述风险阈值;Judging whether the predicted probability of occurrence of heart failure is greater than the risk threshold;
    若所述心衰发生预测概率大于所述风险阈值,则判定所述用户的心衰发生 风险为高风险等级;If the predicted probability of occurrence of heart failure is greater than the risk threshold, determining that the risk of occurrence of heart failure of the user is a high risk level;
    若所述心衰发生预测概率不大于所述风险阈值,判断所述心衰发生预测概率是否处于第一预设范围内;If the predicted probability of occurrence of heart failure is not greater than the risk threshold, determining whether the predicted probability of occurrence of heart failure is within a first preset range;
    若所述心衰发生预测概率处于第一预设范围内,则判定所述用户的心衰发生风险为中风险等级;If the predicted probability of occurrence of heart failure is within the first preset range, determining that the risk of occurrence of heart failure of the user is a medium risk level;
    若所述心衰风险预测概率不处于第一预设范围内,则判定所述用户的心衰发生风险为低风险等级。If the heart failure risk prediction probability is not within the first preset range, it is determined that the heart failure risk of the user is a low risk level.
  15. 根据权利要求14所述的计算机设备,其中,所述将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,得到对应的心衰风险预测概率的步骤之后,包括:14. The computer device according to claim 14, wherein the output result is input to a preset classification module, and the output result is normalized by the classification module to obtain a corresponding heart failure risk prediction After the probabilistic steps, include:
    当所述用户的心衰发生风险为高风险等级状态或中风险等级状态时,生成预警信息,其中,所述预警信息包括所述心衰发生预测概率以及对应的风险等级信息;When the user's heart failure occurrence risk is a high-risk level state or a medium-risk level state, generating early warning information, where the early warning information includes the predicted probability of the occurrence of heart failure and corresponding risk level information;
    获取与心衰预防相关的建议信息;以及,Obtain advice related to heart failure prevention; and,
    获取所述用户的身份信息;Obtaining the identity information of the user;
    根据所述身份信息,将所述预警信息与所述建议信息发送至与所述身份信息对应的用户终端。According to the identity information, the warning information and the suggestion information are sent to the user terminal corresponding to the identity information.
  16. 一种计算机可读存储介质,其上存储有计算机程序,其中,所述计算机程序被处理器执行时实现一种病理数据的分析方法,其中,所述病理数据的分析方法包括以下步骤:A computer-readable storage medium has a computer program stored thereon, wherein when the computer program is executed by a processor, a method for analyzing pathological data is realized, wherein the method for analyzing pathological data includes the following steps:
    采集用户的病理数据;Collect pathological data of users;
    对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据;Perform feature extraction on the pathological data to obtain specified feature data related to the risk of heart failure, where the specified feature data includes physiological signal feature data, vital signs feature data, and case text feature data;
    获取与心衰发生风险相关的所述用户的结构化特征数据,其中,所述结构化特征数据包括实验室检查特征数据与人口统计学特征数据;Acquiring structured characteristic data of the user related to the risk of occurrence of heart failure, wherein the structured characteristic data includes laboratory examination characteristic data and demographic characteristic data;
    对所述指定特征数据与所述结构化特征数据进行拼接处理,得到拼接处理后的融合特征数据;Performing splicing processing on the designated characteristic data and the structured characteristic data to obtain merged characteristic data after splicing;
    将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果;The fusion feature data is used as the input of the preset attention module, and the attention weight corresponding to each fusion feature in the fusion feature data is generated by the attention module, and the attention weight is adjusted according to the attention weight. Each fusion feature in the fusion feature data is subjected to weighted summation processing to obtain a corresponding output result;
    将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,生成与所述用户对应的心衰发生预测概率。The output result is input to a preset classification module, and the output result is normalized by the classification module to generate a predicted probability of occurrence of heart failure corresponding to the user.
  17. 根据权利要求16所述的计算机可读存储介质,其中,所述对所述病理数据进行特征提取,得到与心衰发生风险相关的指定特征数据,其中,所述指定特征数据包括生理信号特征数据、生命体征特征数据以及病例文本特征数据的步骤,包括:The computer-readable storage medium according to claim 16, wherein the characteristic extraction of the pathological data is performed to obtain designated characteristic data related to the risk of heart failure, wherein the designated characteristic data includes physiological signal characteristic data The steps of vital signs feature data and case text feature data include:
    采用卷积神经网络对所述病理数据中的生理信号数据进行特征提取,得到 与所述生理信号数据对应的生理信号特征数据;以及,Using a convolutional neural network to perform feature extraction on the physiological signal data in the pathological data to obtain physiological signal feature data corresponding to the physiological signal data; and,
    采用循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据;以及,Perform feature extraction on vital sign data in the pathological data by using a recurrent neural network to obtain corresponding vital sign feature data; and,
    采用中文自然语言处理技术对所述病理数据中的病例文本数据进行关键特征提取,得到对应的病例文本特征数据。Using Chinese natural language processing technology to extract key features from the case text data in the pathological data, to obtain corresponding case text feature data.
  18. 根据权利要求17所述的计算机可读存储介质,其中,所述采用循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到对应的生命体征特征数据的步骤,包括:18. The computer-readable storage medium according to claim 17, wherein the step of using a cyclic neural network to extract features of vital signs in the pathological data to obtain corresponding feature data of vital signs comprises:
    采用所述循环神经网络对所述病理数据中的生命体征数据进行特征提取,得到第一生命体征特征数据;Using the recurrent neural network to perform feature extraction on vital sign data in the pathological data to obtain first vital sign feature data;
    判断所述第一生命体征特征数据中是否存在缺失值;Judging whether there are missing values in the first vital sign feature data;
    若所述第一生命体征特征数据中存在缺失值,则获取所述第一生命体征特征数据中的数据缺失位置;If there is a missing value in the first vital sign characteristic data, acquiring the data missing position in the first vital sign characteristic data;
    获取与指定数据缺失位置对应的上次特征观测值,以及获取所述第一生命体征特征数据的均值,其中,所述指定数据缺失位置为所有所述数据缺失位置的任意一个数据缺失位置;Acquiring the last characteristic observation value corresponding to the designated data missing position, and acquiring the mean value of the first vital sign characteristic data, wherein the designated data missing position is any data missing position of all the data missing positions;
    根据所述上次特征观测值与所述均值,调用预设的计算公式计算出与所述指定数据缺失位置对应的指定填充值;使用所述指定填充值对所述指定数据缺失位置进行数据填充处理;According to the last feature observation value and the average value, call a preset calculation formula to calculate a designated filling value corresponding to the designated data missing position; use the designated filling value to perform data filling on the designated data missing position deal with;
    获取对所述第一生命体征特征数据中所有的数据缺失位置进行对应的数据填充处理后得到的第二生命体征特征数据;Acquiring second vital sign feature data obtained after performing corresponding data filling processing on all missing positions in the first vital sign feature data;
    将所述第二生命体征特征数据作为所述生命体征特征数据。Use the second vital sign characteristic data as the vital sign characteristic data.
  19. 根据权利要求16所述的计算机可读存储介质,其中,所述将所述融合特征数据作为预设的注意力模块的输入,通过所述注意力模块生成与所述融合特征数据中每一个融合特征一一对应的注意力权重,并根据所述注意力权重对所述融合特征数据中每一个融合特征进行加权求和处理,得到对应的输出结果的步骤之后,包括:The computer-readable storage medium according to claim 16, wherein the fusion feature data is used as the input of a preset attention module, and each fusion of the fusion feature data is generated by the attention module The feature has one-to-one correspondence with attention weights, and performing weighted summation processing on each fused feature in the fused feature data according to the attention weight to obtain the corresponding output result, including:
    根据所述注意力权重,按照预设规则获取与每一类模态特征数据分别对应的重要性系数,其中,所述模态特征数据包括生理信号特征数据、生命体征特征数据、病例文本特征数据、实验室检查特征数据以及人口统计学特征数据;According to the attention weight, the importance coefficient corresponding to each type of modal feature data is obtained according to preset rules, wherein the modal feature data includes physiological signal feature data, vital sign feature data, and case text feature data , Laboratory examination characteristic data and demographic characteristic data;
    将所有所述重要性系数按照数值从大到小的顺序进行排序,得到对应的排序结果;Sort all the importance coefficients in descending order of numerical value to obtain the corresponding sorting result;
    根据所述排序结果,生成每一类所述模态特征数据对应于心衰发生风险的重要性预测报告;According to the sorting result, generating the importance prediction report of each type of the modal characteristic data corresponding to the risk of occurrence of heart failure;
    展示所述重要性预测报告。Show the importance forecast report.
  20. 根据权利要求16所述的计算机可读存储介质,其中,所述将所述输出结果输入至预设的分类模块,通过所述分类模块对所述输出结果进行归一化处理,得到与所述用户对应的心衰发生预测概率的步骤之后,包括:The computer-readable storage medium according to claim 16, wherein said inputting said output result to a preset classification module, and performing normalization processing on said output result through said classification module to obtain After the user's corresponding steps of predicting the probability of occurrence of heart failure, include:
    获取预设的风险阈值;Obtain the preset risk threshold;
    判断所述心衰发生预测概率是否大于所述风险阈值;Judging whether the predicted probability of occurrence of heart failure is greater than the risk threshold;
    若所述心衰发生预测概率大于所述风险阈值,则判定所述用户的心衰发生风险为高风险等级;If the predicted probability of occurrence of heart failure is greater than the risk threshold, determining that the risk of occurrence of heart failure of the user is a high risk level;
    若所述心衰发生预测概率不大于所述风险阈值,判断所述心衰发生预测概率是否处于第一预设范围内;If the predicted probability of occurrence of heart failure is not greater than the risk threshold, determining whether the predicted probability of occurrence of heart failure is within a first preset range;
    若所述心衰发生预测概率处于第一预设范围内,则判定所述用户的心衰发生风险为中风险等级;If the predicted probability of occurrence of heart failure is within the first preset range, determining that the risk of occurrence of heart failure of the user is a medium risk level;
    若所述心衰风险预测概率不处于第一预设范围内,则判定所述用户的心衰发生风险为低风险等级。If the heart failure risk prediction probability is not within the first preset range, it is determined that the heart failure risk of the user is a low risk level.
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