WO2021112515A3 - Nano-cement comprising copper-doped bioactive glass nanoparticle, and preparing method therefor - Google Patents

Nano-cement comprising copper-doped bioactive glass nanoparticle, and preparing method therefor Download PDF

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Publication number
WO2021112515A3
WO2021112515A3 PCT/KR2020/017315 KR2020017315W WO2021112515A3 WO 2021112515 A3 WO2021112515 A3 WO 2021112515A3 KR 2020017315 W KR2020017315 W KR 2020017315W WO 2021112515 A3 WO2021112515 A3 WO 2021112515A3
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WO
WIPO (PCT)
Prior art keywords
cement
nano
copper
method therefor
preparing method
Prior art date
Application number
PCT/KR2020/017315
Other languages
French (fr)
Korean (ko)
Other versions
WO2021112515A2 (en
Inventor
김해원
강민실
김광진
박정휘
서정주
이정환
이해형
놀리스조나단
Original Assignee
단국대학교 천안캠퍼스 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 단국대학교 천안캠퍼스 산학협력단 filed Critical 단국대학교 천안캠퍼스 산학협력단
Publication of WO2021112515A2 publication Critical patent/WO2021112515A2/en
Publication of WO2021112515A3 publication Critical patent/WO2021112515A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention relates to a nano-cement comprising copper-bioactive glass nanoparticle (Cu-BGn), wherein the nano-cement can deposit hydroxyapatite in a simulated body fluid (SBF) comprising magnesium, calcium, and phosphate ions. The present invention provides a nano-cement having an antimicrobial effect against bacterial infection of tissue as well as tissue regeneration by doping Cu ions on bioactive nanoparticles having effects of angiogenesis and bone formation, and a preparing method therefor.
PCT/KR2020/017315 2019-12-02 2020-11-30 Nano-cement comprising copper-doped bioactive glass nanoparticle, and preparing method therefor WO2021112515A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2019-0158102 2019-12-02
KR1020190158102A KR102361469B1 (en) 2019-12-02 2019-12-02 nanocement comprising copper doped bioactive glass nanoparticle and preparation method thereof

Publications (2)

Publication Number Publication Date
WO2021112515A2 WO2021112515A2 (en) 2021-06-10
WO2021112515A3 true WO2021112515A3 (en) 2021-07-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2020/017315 WO2021112515A2 (en) 2019-12-02 2020-11-30 Nano-cement comprising copper-doped bioactive glass nanoparticle, and preparing method therefor

Country Status (2)

Country Link
KR (1) KR102361469B1 (en)
WO (1) WO2021112515A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110087081A (en) * 2010-01-25 2011-08-02 한국화학연구원 High-injectable calcium based cement composition
KR20160060492A (en) * 2014-11-20 2016-05-30 단국대학교 천안캠퍼스 산학협력단 A bioactive nanocomposite calcium phosphate bone cement composition and a kit for preparing the same
KR20190119909A (en) * 2018-04-13 2019-10-23 단국대학교 천안캠퍼스 산학협력단 Dentin Adhesive Composition Comprising Copper Doped Bioactive Nanoparticles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0564658A (en) * 1991-09-09 1993-03-19 Nippon Electric Glass Co Ltd Bioactive cement and manufacture thereof
KR100831348B1 (en) * 2006-10-27 2008-05-22 한국기계연구원 Nanoporous Bioactive Glass With 3-D Pore Structure and Preparation Method Thereof
KR20190080556A (en) * 2017-12-28 2019-07-08 단국대학교 천안캠퍼스 산학협력단 Bacterial cell membrane-adherent bioactive glass nanoparticles

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110087081A (en) * 2010-01-25 2011-08-02 한국화학연구원 High-injectable calcium based cement composition
KR20160060492A (en) * 2014-11-20 2016-05-30 단국대학교 천안캠퍼스 산학협력단 A bioactive nanocomposite calcium phosphate bone cement composition and a kit for preparing the same
KR20190119909A (en) * 2018-04-13 2019-10-23 단국대학교 천안캠퍼스 산학협력단 Dentin Adhesive Composition Comprising Copper Doped Bioactive Nanoparticles

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BARI ALESSANDRA; BLOISE NORA; FIORILLI SONIA; NOVAJRA GIORGIA; VALLET-REGÍ MARIA; BRUNI GIOVANNA; TORRES-PARDO ALMUDENA; GONZÁLEZ-: "Copper-containing mesoporous bioactive glass nanoparticles as multifunctional agent for bone regeneration", ACTA BIOMATERIALIA, ELSEVIER, AMSTERDAM , NL, vol. 55, 12 April 2017 (2017-04-12), Amsterdam , NL, pages 493 - 504, XP085034292, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2017.04.012 *
KANG MIN SIL; LEE NA-HYUN; SINGH RAJENDRA K.; MANDAKHBAYAR NANDIN; PEREZ ROMAN A.; LEE JUNG-HWAN; KIM HAE-WON: "Nanocements produced from mesoporous bioactive glass nanoparticles", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 162, 3 February 2018 (2018-02-03), AMSTERDAM, NL, pages 183 - 199, XP085355511, ISSN: 0142-9612, DOI: 10.1016/j.biomaterials.2018.02.005 *
LIANG, W. ET AL.: "Bioactive comparison of a borate, phosphate and silicate glass", JOURNAL OF MATERIALS RESEARCH, vol. 21, no. 1, 2006, pages 125 - 131 *

Also Published As

Publication number Publication date
WO2021112515A2 (en) 2021-06-10
KR102361469B1 (en) 2022-02-10
KR20210069151A (en) 2021-06-11

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