WO2021097703A1 - Image reconstruction method, apparatus and device, and storage medium - Google Patents

Image reconstruction method, apparatus and device, and storage medium Download PDF

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WO2021097703A1
WO2021097703A1 PCT/CN2019/119681 CN2019119681W WO2021097703A1 WO 2021097703 A1 WO2021097703 A1 WO 2021097703A1 CN 2019119681 W CN2019119681 W CN 2019119681W WO 2021097703 A1 WO2021097703 A1 WO 2021097703A1
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sampled
data
sample
under
deep learning
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PCT/CN2019/119681
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French (fr)
Chinese (zh)
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王珊珊
郑海荣
祁可翰
刘新
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深圳先进技术研究院
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/002D [Two Dimensional] image generation

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  • This application relates to the field of image processing technology, for example, to an image reconstruction method, device, device, and storage medium.
  • CT computed tomography
  • MRI magnetic resonance imaging
  • positron emission tomography positron emission tomography
  • PET positron emission tomography
  • magnetic resonance equipment in order to enhance the clinical practicability of magnetic resonance imaging technology and shorten the scanning time, magnetic resonance equipment often uses a sampling frequency far lower than the Nyquist sampling frequency for data sampling to obtain target objects in non-Cartesian
  • the under-sampling frequency domain data in the coordinate system is then reconstructed from the under-sampling frequency domain data in the non-Cartesian coordinate system to form a high-definition image of the target object.
  • the current image reconstruction method based on the under-sampled data in a non-Cartesian coordinate system has a longer image reconstruction time and a slower imaging speed.
  • One of the objectives of the embodiments of the present application is to provide an image reconstruction method, device, equipment, and storage medium to solve the problem of image reconstruction time when performing image reconstruction based on the under-sampling number in a non-Cartesian coordinate system in the prior art. Long technical problem.
  • an image reconstruction method including:
  • the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system acquired based on a preset sampling mode;
  • the deep learning network is based on the under-sampled sample frequency domain data and the imaging target in the non-Cartesian coordinate system of multiple imaging targets Fully sampled sample images, obtained by training the initial deep learning network.
  • inputting sampled data into a trained deep learning network for processing to obtain a reconstructed image corresponding to the sampled data includes:
  • performing reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data includes:
  • the method before inputting the sampled data into the trained deep learning network for image reconstruction, the method further includes:
  • each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on a preset sampling mode; the fully sampled sample image is used to predict the image output by the initial deep learning network Compare; the interval between two adjacent sampling points in the preset sampling mode is not uniform;
  • the initial deep learning network is iteratively trained, and the training is stopped when the preset conditions are met, and the trained deep learning network is obtained.
  • Obtaining multiple training samples includes:
  • sample sampling data of each imaging target based on the preset sampling mode, the sample sampling data is the under-sampling frequency domain data in a non-Cartesian coordinate system;
  • the fully sampled sample image and sample sample data corresponding to each imaging target are used as a training sample.
  • the initial deep learning network includes: a coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module that are sequentially cascaded;
  • the initial deep learning network is iteratively trained, and the training is stopped when the preset conditions are met.
  • the deep learning network obtained after training includes:
  • the preset sampling mode includes radial sampling or spiral scanning sampling.
  • an image reconstruction device including:
  • the sampling module is used to obtain sampling data of the target object; wherein, the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system obtained based on a preset sampling mode;
  • the reconstruction module is used to input the sampled data into the trained deep learning network for processing to obtain the reconstructed image corresponding to the sampled data; among them, the deep learning network is based on the frequency domain of under-sampled samples in a non-Cartesian coordinate system of multiple imaging targets The data and the fully sampled sample images of the imaging target are obtained by training the initial deep learning network.
  • an embodiment of the present application provides an image reconstruction device, including a memory, a processor, and computer-readable instructions stored in the memory and running on the processor.
  • the processor executes the computer-readable instructions to implement the above-mentioned first On the one hand, the steps of any method.
  • the embodiments of the present application provide a computer-readable storage medium, the computer-readable storage medium stores computer-readable instructions, and the computer-readable instructions implement the steps of any one of the methods in the first aspect when the computer-readable instructions are executed by a processor. .
  • embodiments of the present application provide a computer program product, which when the computer program product runs on an image reconstruction device, causes the image reconstruction device to execute the method in any one of the above-mentioned first aspects.
  • the embodiment of the present application has the beneficial effect that the sampled data of the target object is processed through the trained deep learning network, thereby obtaining the reconstructed image corresponding to the sampled data, and realizing the image of the sampled data of the target object Reconstruction; where the sampled data is the under-sampled frequency domain data in a non-Cartesian coordinate system, and the deep learning network is based on the under-sampled sample frequency domain data of multiple imaging targets and the fully sampled sample image of the imaging target, and the initial deep learning Obtained from network training.
  • the deep learning network in the embodiment of the application is pre-trained and can be directly based on The input sampling data obtains the corresponding reconstruction graph without manual selection/adjustment of parameters such as scale factors, which improves the reconstruction speed of the under-sampled frequency domain data in the non-Cartesian coordinate system; on the other hand, the deep learning network in this application Accelerated calculations can be performed directly based on the graphics processor GPU. Under the premise of ensuring the accuracy of image reconstruction, the image reconstruction time of under-sampling frequency domain data in the non-Cartesian coordinate system is further shortened.
  • FIG. 1 is a schematic diagram of the architecture of an image reconstruction system provided by an embodiment of the present application.
  • FIG. 2 is a schematic flowchart of an image reconstruction method provided by an embodiment of the present application.
  • FIG. 3 is a schematic diagram of the architecture of a deep learning network provided by an embodiment of the present application.
  • FIG. 4 is a schematic diagram of a process of obtaining a reconstructed image corresponding to sampling data according to an embodiment of the present application
  • FIG. 5 is a schematic diagram of a process of acquiring a trained deep learning network provided by an embodiment of the present application
  • FIG. 6 is a schematic diagram of a process of obtaining training samples provided by an embodiment of the present application.
  • FIG. 7 is a schematic diagram of a process flow for iterative training of a deep learning network provided by an embodiment of the present application.
  • FIG. 8 is a schematic diagram of the composition of an image reconstruction device provided by an embodiment of the present application.
  • FIG. 9 is a schematic diagram of the composition of an image reconstruction device provided by another embodiment of the present application.
  • FIG. 10 is a schematic structural diagram of an image reconstruction device provided by an embodiment of the present application.
  • FIG. 1 is a schematic diagram of the architecture of an image reconstruction system provided by an embodiment of the application.
  • the image reconstruction system includes an image acquisition device 10 and an image reconstruction device 20.
  • the image reconstruction system includes an image acquisition device 10 and an image reconstruction device 20.
  • the image acquisition device 10 refers to a device for providing medical imagery to users.
  • a device for providing medical imagery to users For example, magnetic resonance equipment.
  • the image acquisition device 10 can obtain different sampling data according to different sampling modes, including but not limited to non-uniform under-sampling frequency domain data, uniform under-sampling frequency domain data, uniform full-sampling frequency domain data, and the like.
  • the sampling mode is spiral scanning sampling
  • the sampling data is non-uniform under-sampling frequency domain data in a non-Cartesian coordinate system.
  • the image reconstruction device 20 is configured to receive sampling data in a non-Cartesian coordinate system sent by the image acquisition device 10 to perform image reconstruction.
  • the image reconstruction device 20 communicates with the image acquisition device 10 through a network.
  • the aforementioned networks include, but are not limited to, wide area networks and local area networks.
  • the image reconstruction device 20 may be a cloud server.
  • the cloud server may be a server that implements a single function or a server that implements multiple functions. Specifically, it may be an independent physical server or a cluster of physical servers.
  • the image reconstruction method provided in the embodiment of the present application is executed by the image reconstruction device 20, and the image acquisition device 10 is a magnetic resonance device.
  • the magnetic resonance equipment stores the sampling points in a preset arrangement, generates sampling data, and sends the sampling data to the image reconstruction device 20, and the image reconstruction device 20 performs subsequent image reconstruction.
  • the arrangement method is determined by the sampling mode.
  • the sampling points are evenly distributed on the grid points.
  • the image reconstruction device 20 can obtain the signal intensity of each voxel at a certain position in the two-dimensional plane through the inverse Fourier transform, and convert it into the corresponding gray value to obtain the magnetic resonance image.
  • the image reconstruction device 20 obtains the under-sampling data in the non-Cartesian coordinate system collected by the magnetic resonance device 10, and inputs the under-sampling data in the non-Cartesian coordinate system to the depth after training
  • the learning network performs reconstruction processing and directly obtains the reconstructed image of the target object.
  • Fig. 2 is a schematic flowchart of an image reconstruction method provided by an embodiment of the application.
  • the image reconstruction method is executed by the image reconstruction device shown in Fig. 1.
  • the image reconstruction method includes:
  • the target object is a specimen to be detected by a medical imaging device.
  • the target object includes a simulation body, a living body (animal or human body), an isolated organ or tissue, and the like.
  • the data collected by the preset sampling mode may be data in a non-Cartesian coordinate system; after the sampling point in the preset sampling mode is projected to the Cartesian coordinate system, the interval between two adjacent sampling points It can be uneven.
  • the preset sampling mode may include any one of the following: radial sampling, spiral trajectory sampling, rotating scan sampling, echo planar imaging (EPI) based sampling, and interleave sampling.
  • EPI relies on the continuous reverse direction switching of the gradient coil after a pulse excitation to collect a series of gradient echo signals.
  • the preset sampling mode is that the magnetic resonance device scans the target object based on the spiral trajectory.
  • Spiral trajectory scanning generally starts from the center of the storage space of the sampling point, and then expands outward in a spiral shape. That is to say, the sampling points after one excitation are not arranged sequentially on a two-dimensional grid.
  • the gradient waveform By adjusting the gradient waveform, the data is filled along the spiral trajectory.
  • each sampling point is located in the polar coordinate plane.
  • a series of spiral trajectories on (non-Cartesian coordinate system) are not regular rectangular grid points; after the sampling points are projected to the Cartesian coordinate system, the intervals between adjacent sampling points are not the same.
  • the magnetic resonance device sends a series of initial sampling points located on the polar coordinate plane to the image reconstruction device, so that the image reconstruction device performs image reconstruction on the data to obtain a reconstructed image of the target object.
  • the deep learning network in this embodiment is a deep learning network constructed based on a deep learning framework.
  • the input of the deep learning network is frequency-domain data of under-sampled samples in a non-Cartesian coordinate system, and the output is a high-precision image close to full sampling, that is, a reconstructed image.
  • multiple preset sampling modes may correspond to one deep learning network, or each preset sampling model may correspond to one deep learning network.
  • the division should be based on the sampling principle in the preset sampling mode, which is not limited here.
  • the deep learning network is based on the under-sampled sample frequency domain data in the non-Cartesian coordinate system of multiple imaging targets and the fully sampled sample image of the imaging target, which is obtained by training the initial deep learning network.
  • the frequency domain data of the under-sampled samples in the non-Cartesian coordinate system of the imaging target is obtained by using a preset sampling mode.
  • the full-sampled sample image is used to compare with the predicted image output by the initial deep learning network to be based on The comparison result adjusts the model parameters of the initial deep learning network.
  • the deep learning network includes a cascaded coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module that are sequentially cascaded.
  • the coordinate conversion convolution module is used to receive the input under-sampled frequency domain data in a non-Cartesian coordinate system, and perform convolution operations on the under-sampled frequency-domain data in a non-Cartesian coordinate system to obtain the under-sampled frequency domain data in the non-Cartesian coordinate system.
  • the density compensation convolution module is used to perform density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system.
  • the image reconstruction convolution module is used to reconstruct the under-sampled uniform frequency domain data to obtain the reconstructed image corresponding to the under-sampled uniform frequency domain data.
  • FIG. 3 mainly describes how to obtain the reconstructed image corresponding to the sampling data in S202. Assume that the preset sampling mode is spiral trajectory sampling.
  • the sampled data is input into the trained deep learning network for processing, and the reconstructed image corresponding to the sampled data is obtained, including S2011 to S2013, as follows:
  • S2021 Input the sampled data into the trained deep learning network to perform coordinate conversion, and obtain the under-sampled non-uniform frequency domain data in the Cartesian coordinate system corresponding to the sampled data.
  • the coordinate conversion convolution module receives the input sampling data, that is, the under-sampled frequency domain data in the non-Cartesian coordinate system, and performs convolution operation on the under-sampled frequency domain data in the non-Cartesian coordinate system to obtain the data in the Cartesian coordinate system. Undersample uniform frequency domain data.
  • the convolution operation may be a real number convolution operation or a complex number convolution operation.
  • the coordinate transformation convolution module performs complex convolution operations, and the coordinate transformation convolution module includes a first complex convolution block cascaded in multiple layers.
  • the complex convolution operation of the first complex convolution block can be expressed as:
  • W represents the input sampled data
  • A represents the real part of the sampled data
  • B represents the imaginary part of the sampled data
  • C represents the complex convolution kernel
  • a represents the real part of the complex convolution kernel
  • b represents the imaginary part of the complex convolution kernel.
  • S2022 Perform density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system.
  • the density compensation convolution module includes a second complex convolution block cascaded in multiple layers.
  • the multi-layer second complex convolution block sequentially implements a complex convolution operation to perform density compensation processing on the under-sampled non-uniform frequency domain data.
  • the complex convolution operation is the same as the above formula (1), and will not be repeated here.
  • S2023 Perform reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
  • Image reconstruction convolution module fills the under-sampled uniform frequency domain data to obtain fully sampled uniform frequency domain data; then performs inverse Fourier transform on the uniform frequency domain data to obtain the reconstructed image corresponding to the under-sampled uniform frequency domain data .
  • the image reconstruction convolution module includes a multi-layer cascaded third complex convolution block, and the multi-layer third complex convolution block sequentially implements the filling process of the under-sampled uniform frequency domain data through the complex convolution operation.
  • the complex convolution operation is the same as the above formula (1), and will not be repeated here. From the perspective of signal and image processing, complex numbers introduce phase information compared to real numbers.
  • the phase information of the image provides a detailed description of the shape, edge and direction of the image, which can be used to restore the amplitude information of the image, based on complex convolution operations.
  • the deep learning network has better image reconstruction effects.
  • the accuracy of the reconstructed image is affected by the size of the convolution kernel in the first complex convolution block, the second complex convolution block, and the third complex convolution block.
  • the convolution kernel can be set according to the accuracy requirements of the reconstructed image.
  • the size is not limited here.
  • FIG. 4 is a schematic structural diagram of a deep learning network provided by an embodiment of the application.
  • the deep learning network includes cascaded coordinate conversion convolution modules that are sequentially cascaded, Density compensation convolution module and image reconstruction convolution module.
  • the input of the coordinate conversion convolution module is sampled data, and the output is under-sampling non-uniform frequency domain data in Cartesian coordinates;
  • the input of the density compensation convolution module is under-sampling frequency Domain data, the output is the under-sampled uniform frequency domain data in the Cartesian coordinate system,
  • the input of the image reconstruction convolution module is the under-sampled uniform frequency domain data, and the output is the reconstructed image.
  • the coordinate conversion convolution module includes a first complex convolution block cascaded in multiple layers.
  • the density compensation convolution module includes a multi-layer cascaded second complex convolution block;
  • the image reconstruction convolution module includes a multi-layer cascaded third complex convolution block.
  • the coordinate conversion convolution module receives the under-sampled frequency domain data in a non-Cartesian coordinate system, and the cascaded first complex convolution block sequentially performs complex convolutions on the under-sampled frequency domain data in the non-Cartesian coordinate system.
  • the first second complex convolution block in the second complex convolution block of multi-layer cascade receives the output of the last first complex convolution block (that is, the under-sampled frequency domain data in the Cartesian coordinate system) , And perform complex convolution operations on the output, and then the cascaded second complex convolution block sequentially performs complex convolution operations on the output of the previous second complex convolution block, until the output under-sampling in the Cartesian coordinate system is uniform Frequency domain data;
  • the cascaded third complex convolution block sequentially performs complex convolution operations on the under-sampled uniform frequency domain data, that is, the output of the previous third complex convolution block is the input of the next third complex convolution block, up to multiple
  • the third complex convolution block all completes the complex convolution operation and outputs the reconstructed image.
  • the advantageous effect of the image reconstruction method provided in this embodiment is that the sampled data of the target object is processed through the trained deep learning network, so as to obtain the reconstructed image corresponding to the sampled data.
  • the image reconstruction of the sampled data of the target object is realized; among them, the sampled data is the under-sampled frequency domain data in a non-Cartesian coordinate system, and the deep learning network is based on the under-sampled sample frequency domain data of multiple imaging targets and the imaging target's image reconstruction. Fully sampled sample images, obtained by training the initial deep learning network.
  • the deep learning network in the embodiment of the application is pre-trained and can be directly based on The input sampling data obtains the corresponding reconstruction graph without manual selection/adjustment of parameters such as scale factors, which improves the reconstruction speed of the under-sampled frequency domain data in the non-Cartesian coordinate system; on the other hand, the deep learning network in this application Accelerated calculations can be directly based on the graphics processor GPU. Under the premise of ensuring the accuracy of image reconstruction, the image reconstruction time of under-sampling frequency domain data in non-Cartesian coordinates is further shortened.
  • FIG. 5 is a schematic diagram of a process for obtaining a trained deep learning network according to an embodiment of the application.
  • FIG. 5 mainly describes how to obtain the trained deep learning network in step S202.
  • the method for obtaining the trained deep learning network includes S501 to S502, which are specifically as follows:
  • each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on a preset sampling mode; the fully sampled sample image is used for output from the initial deep learning network The predicted images are compared; the interval between two adjacent sampling points in the preset sampling mode is not uniform.
  • the multiple training samples correspond to multiple imaging targets, and the training samples correspond to the imaging targets on a one-to-one basis.
  • the imaging targets may include the target object in step 202, which is a specimen used for detection by a medical imaging device.
  • the imaging target may refer to objects at different positions on a target specimen, or may refer to different target specimens.
  • the fully sampled sample image of the imaging target can be acquired from a medical imaging device based on a low-power under-sampling factor.
  • the sample sampling data in each training sample can be obtained by processing the imaging target based on a preset sampling mode.
  • FIG. 6 mainly describes how to obtain training samples in the foregoing S501.
  • the steps of obtaining multiple training samples include S5011 to S5013, which are specifically as follows:
  • the hospital imaging equipment may be a magnetic resonance equipment, and the magnetic resonance equipment may acquire a scan image of the imaging target from the magnetic resonance equipment based on a low-power under-collection factor, and then preprocess the acquired scan image and process it The latter image is used as a fully sampled sample image of the imaging target.
  • the preprocessing method can include image selection processing, normalization processing, and so on. Image selection processing is used to extract some images with low quality or with more noise data to improve the efficiency of training.
  • the normalization process is to facilitate the input of the fully sampled image in the complex convolutional neural network to adapt to subsequent training.
  • S5012 Acquire sample sampling data of each imaging target based on a preset sampling mode, where the sample sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system.
  • the initial under-sampling frequency domain data is acquired from the same MRI device based on the preset sampling mode, that is, the frequency domain data before imaging.
  • the imaging target is in a non-Cartesian coordinate system. Frequency domain data of under-sampled samples.
  • the acquisition of multiple training samples preprocesses the fully sampled initial scan image of the imaging target obtained by the medical imaging equipment to obtain the fully sampled image of the imaging target, which partially eliminates the adverse effects caused by singular sample data and improves Training efficiency.
  • S502 Perform iterative training on the initial deep learning network according to multiple training samples, and stop training when a preset condition is met, to obtain a trained deep learning network.
  • the structure of the initial deep learning network is the same as the structure of the deep learning network in step 202.
  • the initial deep learning network includes a cascaded coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module.
  • the iterative training of the deep learning network based on multiple training samples includes, for each training sample, using a fully sampled image in the training sample as a label, and sample sampling data in the training sample as input.
  • Obtain the predicted image output by the deep learning network compare the predicted image output by the deep learning network with the fully sampled image, and adjust the model parameters of the deep learning network according to the comparison results; after that, start the next round of iterative training; if the current number of training When the preset number of iterations is met, or the error between the accuracy of the predicted image obtained in this iterative training and the accuracy of the fully sampled sample image in the training sample is less than or equal to the preset error threshold, the training is stopped, and the trained deep learning network is obtained .
  • the error is calculated by using a preset loss function.
  • the training loss function may be a minimum absolute value deviation loss function, a minimum square error loss function, etc., which are not specifically limited here.
  • the loss function is used to calculate the error value between the predicted image output by the deep learning network and the fully sampled image. For example, image resolution difference, image sharpness difference, or image similarity difference, etc.
  • the deep learning network is trained based on multiple training samples, and the model parameters of the complex neural network model are optimized. Based on this training, the deep learning network is input to the non-Cartesian coordinate system of any target object.
  • a high-resolution image of the target object that is, a reconstructed image
  • the high-resolution image is an image close to a fully-sampled image, which can meet the actual application requirements in medical imaging.
  • the deep learning network can be trained based on an end-to-end training mechanism. Please also refer to FIG. 7.
  • FIG. 7 mainly describes the iterative training of the deep learning network in step S502 as an example.
  • the initial deep learning network is iteratively trained, and when the preset conditions are met, the training is stopped to obtain the trained deep learning network including:
  • S701 Initialize model parameters of the initial deep learning network.
  • the initial values of the model parameters are preset values.
  • S702 Perform a convolution operation on the sample sample data in the training sample by the coordinate conversion convolution module to obtain the under-sampled non-uniform sample data in the Cartesian coordinate system.
  • the sample sampling data of the training samples are input to the coordinate conversion convolution module in the initial deep learning network, and forward propagation based on the current model parameters of the initial deep learning network.
  • the first complex convolution block cascaded in the coordinate conversion convolution module sequentially performs complex convolution operations, until multiple first complex convolution blocks have completed the complex convolution operation, and the under-sampling frequency in the Cartesian coordinate system is generated. Domain data.
  • S703 Perform density compensation on the under-sampled non-uniform sample data in the Cartesian coordinate system through the density compensation convolution module, and generate corresponding under-sampled uniform sample data.
  • This step is the same as the processing of step S2022, and will not be repeated here.
  • S704 Perform a convolution operation on the under-sampled uniform sample data through the image reconstruction convolution module to generate a predicted image corresponding to the under-sampled uniform sample data.
  • This step is the same as the processing of step S2023, and will not be repeated here.
  • the preset condition may be: the current number of training reaches the preset number of iterations, or the error between the accuracy of the predicted image obtained in this iteration training and the accuracy of the fully sampled sample image in the training sample is less than or equal to the preset error threshold .
  • the current model parameters are saved, and the deep learning network is obtained.
  • the iterative training method of the deep learning network adopts an end-to-end training method, and directly inputs the sample data obtained by the collection into the deep learning network to obtain a predicted image.
  • the predicted image is combined with the fully sampled samples in the training sample.
  • the image comparison will get an error, the error is back propagated, and the model parameters of the deep learning network are updated until the accuracy error between the output of the deep learning network and the fully sampled sample image is less than the preset threshold.
  • This method saves the data labeling work required before the execution of each independent learning task, and can directly perform training calculations based on the graphics processor GPU, which improves the training efficiency.
  • the embodiment of the present invention further provides an embodiment of an apparatus for implementing the foregoing method embodiment.
  • FIG. 8 is a schematic diagram of the composition of an image reconstruction device provided by an embodiment of the application.
  • the image reconstruction device 80 includes: a sampling module 801 and a reconstruction module 802.
  • the sampling module 801 is configured to obtain sampling data of a target object; wherein the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system obtained based on a preset sampling mode;
  • the reconstruction module 802 is used to input the sampled data into the trained deep learning network for processing, and obtain the reconstructed image corresponding to the sampled data; wherein, the deep learning network is based on the under-sampled sample frequency in the non-Cartesian coordinate system of multiple imaging targets The domain data and the fully sampled sample image of the imaging target are obtained by training the initial deep learning network.
  • the reconstruction module 802 is specifically used for:
  • the reconstruction module 802 is also specifically used for:
  • the image reconstruction device processes the sampled data of the target object through the trained deep learning network, thereby obtaining the reconstructed image corresponding to the sampled data, and realizes the image reconstruction of the sampled data of the target object;
  • the sampled data is For the under-sampled frequency domain data in a non-Cartesian coordinate system
  • the deep learning network is obtained by training the initial deep learning network based on the under-sampled sample frequency domain data of multiple imaging targets and the fully sampled sample image of the imaging target.
  • the deep learning network in the embodiment of the application is pre-trained and can be directly based on The input sampling data obtains the corresponding reconstruction graph without manual selection/adjustment of parameters such as scale factors, which improves the reconstruction speed of the under-sampled frequency domain data in the non-Cartesian coordinate system; on the other hand, the deep learning network in this application Accelerated calculations can be directly based on the graphics processor GPU. Under the premise of ensuring the accuracy of image reconstruction, the image reconstruction time of under-sampling frequency domain data in non-Cartesian coordinates is further shortened.
  • FIG. 9 is a schematic diagram of the composition of an image reconstruction device provided by another embodiment of the application. As shown in FIG. 9, the image reconstruction device 80 further includes a training module 803.
  • each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on a preset sampling mode; the fully sampled sample image is used to predict the image output by the initial deep learning network Compare; the interval between two adjacent sampling points in the preset sampling mode is not uniform;
  • the initial deep learning network is iteratively trained, and the training is stopped when the preset conditions are met, and the trained deep learning network is obtained.
  • the training module 803 is specifically used for:
  • sample sampling data of each imaging target based on the preset sampling mode, the sample sampling data is the under-sampling frequency domain data in a non-Cartesian coordinate system;
  • the fully sampled sample image and sample sample data corresponding to each imaging target are used as a training sample.
  • the deep learning network includes: a coordinate transformation convolution module, an inverse Fourier transformation module, and a second complex convolution layer that are sequentially cascaded; the training module 803 is also specifically used for:
  • the coordinate transformation convolution module includes a plurality of cascaded first complex convolution modules
  • the second complex convolution layer includes a plurality of cascaded second complex convolution modules; the first complex convolution module and the second complex convolution module;
  • the size of the convolution kernel of the complex convolution module is the same.
  • the preset sampling mode includes radial sampling or spiral scanning sampling.
  • the image reconstruction device trains the initial deep learning network based on multiple training samples, and optimizes the model parameters of the initial deep learning network. Based on this training, the deep learning network is used to input any target object.
  • the under-sampling frequency domain data in the Cartesian coordinate system can obtain a high-resolution image of the target object, that is, a reconstructed image.
  • the high-resolution image is an image close to the full-sampled image, which can meet the actual application requirements in medical imaging. .
  • the image reconstruction apparatus provided by the embodiments shown in FIG. 8 and FIG. 9 can be used to implement the technical solutions in the foregoing method embodiments, and their implementation principles and technical effects are similar, and will not be repeated here in this embodiment.
  • Fig. 10 is a schematic diagram of an image reconstruction device provided by an embodiment of the present application.
  • the image reconstruction terminal device 100 of this embodiment includes: at least one processor 1001, a memory 1002, and computer-readable instructions stored in the memory 1002 and executable on the processor 1001.
  • the image reconstruction device further includes a communication component 1003, wherein the processor 1001, the memory 1002, and the communication component 1003 are connected by a bus 1004.
  • the processor 1001 implements the steps in the foregoing image reconstruction method embodiments when executing computer-readable instructions, such as step S201 to step S202 in the embodiment shown in FIG. 2.
  • the processor 1001 executes the computer-readable instructions
  • the functions of the modules/units in the foregoing device embodiments for example, the functions of the modules 801 to 802 shown in FIG. 8 are realized.
  • the computer-readable instructions may be divided into one or more modules/units, and the one or more modules/units are stored in the memory 1002 and executed by the processor 1001 to complete the present application.
  • the one or more modules/units may be a series of computer-readable instruction segments capable of completing specific functions, and the instruction segments are used to describe the execution process of the computer-readable instructions in the image reconstruction device 100.
  • FIG. 10 is only an example of the image reconstruction device and does not constitute a limitation on the image reconstruction device. It may include more or less components than shown in the figure, or a combination of certain components, or different components. Components, such as input and output devices, network access devices, buses, etc.
  • the processor 1001 can be a central processing unit (Central Processing Unit, CPU), other general-purpose processors, digital signal processors (Digital Signal Processor, DSP), application specific integrated circuits (Application Specific Integrated Circuit, ASIC), ready-made Field-Programmable Gate Array (FPGA) or other programmable logic devices, discrete gates or transistor logic devices, discrete hardware components, etc.
  • the general-purpose processor may be a microprocessor or the processor may also be any conventional processor or the like.
  • the memory 1002 may be an internal storage unit of the image reconstruction device, or an external storage device of the image reconstruction device, such as a plug-in hard disk, a smart media card (SMC), or a secure digital (SD) card. Flash Card, etc.
  • the memory 1002 is used to store the computer readable instructions and other programs and data required by the image reconstruction device.
  • the memory 1002 can also be used to temporarily store data that has been output or will be output.
  • the bus can be an Industry Standard Architecture (ISA) bus, Peripheral Component (PCI) bus, or Extended Industry Standard Architecture (EISA) bus, etc.
  • ISA Industry Standard Architecture
  • PCI Peripheral Component
  • EISA Extended Industry Standard Architecture
  • the bus can be divided into address bus, data bus, control bus and so on.
  • the buses in the drawings of this application are not limited to only one bus or one type of bus.
  • the embodiments of the present application also provide a computer-readable storage medium, and the computer-readable storage medium stores computer-readable instructions.
  • the steps in the foregoing method embodiments can be realized.
  • the embodiments of the present application provide a computer program product.
  • the image reconstruction device can implement the steps in the foregoing method embodiments when executed.
  • the integrated unit is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer readable storage medium.
  • the implementation of all or part of the processes in the above-mentioned embodiments and methods in this application can be accomplished by instructing relevant hardware through computer-readable instructions, and the computer-readable instructions can be stored in a computer-readable storage medium.
  • the computer-readable instructions are executed by the processor, they can implement the steps of the foregoing method embodiments.
  • the computer-readable instruction includes computer-readable instruction code
  • the computer-readable instruction code may be in the form of source code, object code, executable file, or some intermediate form.
  • the computer-readable medium may at least include: any entity or device capable of carrying computer-readable instruction codes to the image reconstruction equipment, recording medium, computer memory, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), electric carrier signal, telecommunications signal and software distribution medium.
  • ROM read-only memory
  • RAM random access memory
  • electric carrier signal telecommunications signal and software distribution medium.
  • U disk mobile hard disk, floppy disk or CD-ROM, etc.
  • computer-readable media cannot be electrical carrier signals and telecommunication signals.
  • the disclosed apparatus/network equipment and method may be implemented in other ways.
  • the device/network device embodiments described above are only illustrative.
  • the division of the modules or units is only a logical function division, and there may be other divisions in actual implementation, such as multiple units.
  • components can be combined or integrated into another system, or some features can be omitted or not implemented.
  • the displayed or discussed mutual coupling or direct coupling or communication connection may be indirect coupling or communication connection through some interfaces, devices or units, and may be in electrical, mechanical or other forms.
  • the units described as separate components may or may not be physically separated, and the components displayed as units may or may not be physical units, that is, they may be located in one place, or they may be distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the objectives of the solutions of the embodiments.

Abstract

An image reconstruction method, apparatus and device, and a storage medium. The method comprises: acquiring sampled data of a target object (S201); and inputting the sampled data into a trained deep learning network for processing to obtain a reconstructed image corresponding to the sampled data, wherein the sampled data is under-sampled frequency domain data in a non-Cartesian coordinate system acquired on the basis of a preset sampling mode (S202). Compared with the technical solution of performing image reconstruction on under-sampled frequency domain data in a non-Cartesian coordinate system on the basis of non-uniform fast Fourier transformation, in the method, a deep learning network is pre-trained, and reconstruction can be directly performed to obtain a corresponding image according to under-sampled frequency domain data input in a non-Cartesian coordinate system, without the need to manually select/adjust parameters, such as a scale factor, such that the reconstruction speed of the under-sampled frequency domain data in the non-Cartesian coordinate system is improved.

Description

图像重建方法、装置、设备及存储介质Image reconstruction method, device, equipment and storage medium 技术领域Technical field
本申请涉及图像处理技术领域,例如涉及一种图像重建方法、装置、设备及存储介质。This application relates to the field of image processing technology, for example, to an image reconstruction method, device, device, and storage medium.
背景技术Background technique
在目前的医学影像成像中,如计算机断层成像(computed tomography,CT)、磁共振成像(magnetic resonance imaging,MRI)、正电子发射断层成像(positron emission tomography,PET)中,均需要对目标对象的采样数据进行图像重建,形成扫描区域的高清图像。In the current medical imaging imaging, such as computed tomography (CT), magnetic resonance imaging (magnetic resonance imaging, MRI), positron emission tomography (positron emission tomography, PET), it is necessary to analyze the target object. The sampled data is used for image reconstruction to form a high-definition image of the scanned area.
以磁共振成像MRI为例,为了增强磁共振成像技术在临床上的实用性,缩短扫描时间,磁共振设备经常采用远低于奈奎斯特采样频率进行数据采样,获得目标对象在非笛卡尔坐标系下的欠采样频域数据,然后对该非笛卡尔坐标系下的欠采样频域数据进行图像重建,形成目标对象的高清图像。Taking magnetic resonance imaging MRI as an example, in order to enhance the clinical practicability of magnetic resonance imaging technology and shorten the scanning time, magnetic resonance equipment often uses a sampling frequency far lower than the Nyquist sampling frequency for data sampling to obtain target objects in non-Cartesian The under-sampling frequency domain data in the coordinate system is then reconstructed from the under-sampling frequency domain data in the non-Cartesian coordinate system to form a high-definition image of the target object.
然而,目前基于非笛卡尔坐标系下的欠采样数据进行图像重建的方法,图像重建时间较长,成像速度较慢。However, the current image reconstruction method based on the under-sampled data in a non-Cartesian coordinate system has a longer image reconstruction time and a slower imaging speed.
发明概述Summary of the invention
技术问题technical problem
本申请实施例的目的之一在于:提供一种图像重建方法、装置、设备及存储介质,以解决现有技术中在基于非笛卡尔坐标系下的欠采样数进行图像重建时,图像重建时间长的技术问题。One of the objectives of the embodiments of the present application is to provide an image reconstruction method, device, equipment, and storage medium to solve the problem of image reconstruction time when performing image reconstruction based on the under-sampling number in a non-Cartesian coordinate system in the prior art. Long technical problem.
问题的解决方案The solution to the problem
技术解决方案Technical solutions
为解决上述技术问题,本申请实施例采用的技术方案是:In order to solve the above technical problems, the technical solutions adopted in the embodiments of this application are:
第一方面,本申请实施例提供了一种图像重建方法,包括:In the first aspect, an embodiment of the present application provides an image reconstruction method, including:
获取目标对象的采样数据;其中,采样数据为基于预设采样模式获取的非笛卡尔坐标系下的欠采样频域数据;Acquire sampling data of the target object; wherein, the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system acquired based on a preset sampling mode;
将采样数据输入训练后的深度学习网络进行处理,获得采样数据对应的重建图像;其中,深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及成像目标的全采样样本图像,对初始深度学习网络训练得到。Input the sampled data into the trained deep learning network for processing, and obtain the reconstructed image corresponding to the sampled data; among them, the deep learning network is based on the under-sampled sample frequency domain data and the imaging target in the non-Cartesian coordinate system of multiple imaging targets Fully sampled sample images, obtained by training the initial deep learning network.
在第一方面的一种可能的实现方式中,将采样数据输入训练后的深度学习网络进行处理,获得采样数据对应的重建图像,包括:In a possible implementation of the first aspect, inputting sampled data into a trained deep learning network for processing to obtain a reconstructed image corresponding to the sampled data includes:
将采样数据输入训练后的深度学习网络进行坐标转换,得到采样数据对应的笛卡尔坐标系下的欠采样非均匀频域数据;Input the sampled data into the trained deep learning network for coordinate conversion to obtain the under-sampled non-uniform frequency domain data in the Cartesian coordinate system corresponding to the sampled data;
对笛卡尔坐标系下的欠采样非均匀频域数据进行密度补偿处理,得到笛卡尔坐标系下的欠采样均匀频域数据;Perform density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system;
对欠采样均匀频域数据进行重建处理,得到欠采样均匀频域数据对应的重建图像。Perform reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
在第一方面的一种可能的实现方式中,对欠采样均匀频域数据进行重建处理,得到欠采样均匀频域数据对应的重建图像,包括:In a possible implementation of the first aspect, performing reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data includes:
对欠采样均匀频域数据进行填充处理,得到全采样的均匀频域数据;Fill in the under-sampled uniform frequency domain data to obtain fully-sampled uniform frequency domain data;
对均匀频域数据进行傅里叶逆变换,得到欠采样均匀频域数据对应的重建图像。Perform inverse Fourier transform on the uniform frequency domain data to obtain the reconstructed image corresponding to the under-sampled uniform frequency domain data.
在第一方面的一种可能的实现方式中,将采样数据输入训练后的深度学习网络进行图像重建之前,方法还包括:In a possible implementation of the first aspect, before inputting the sampled data into the trained deep learning network for image reconstruction, the method further includes:
获取多个训练样本,每个训练样本包括成像目标的全采样样本图像和基于预设采样模式对成像目标进行处理获得的样本采样数据;全采样样本图像用于与初始深度学习网络输出的预测图像进行比较;预设采样模式中相邻的两个采样点之间的间隔不均匀;Acquire multiple training samples, each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on a preset sampling mode; the fully sampled sample image is used to predict the image output by the initial deep learning network Compare; the interval between two adjacent sampling points in the preset sampling mode is not uniform;
根据多个训练样本,对初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络。According to multiple training samples, the initial deep learning network is iteratively trained, and the training is stopped when the preset conditions are met, and the trained deep learning network is obtained.
在第一方面的一种可能的实现方式中,用于训练的成像目标有多个;In a possible implementation of the first aspect, there are multiple imaging targets used for training;
获取多个训练样本包括:Obtaining multiple training samples includes:
获取每个成像目标对应的全采样样本图像,全采样样本图像由医学影像设备采集;Obtain the full sample sample image corresponding to each imaging target, and the full sample sample image is collected by the medical imaging equipment;
基于预设采样模式获取每个成像目标的样本采样数据,样本采样数据为非笛卡尔坐标系下的欠采样频域数据;Obtain sample sampling data of each imaging target based on the preset sampling mode, the sample sampling data is the under-sampling frequency domain data in a non-Cartesian coordinate system;
将每个成像目标对应的全采样样本图像和样本采样数据作为一个训练样本。The fully sampled sample image and sample sample data corresponding to each imaging target are used as a training sample.
在第一方面的一种可能的实现方式中,初始深度学习网络包括:依次级联的坐标转换卷积模块、密度补偿卷积模块以及图像重建卷积模块;In a possible implementation of the first aspect, the initial deep learning network includes: a coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module that are sequentially cascaded;
根据多个所述训练样本,对初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络包括:According to a plurality of the training samples, the initial deep learning network is iteratively trained, and the training is stopped when the preset conditions are met. The deep learning network obtained after training includes:
初始化初始深度学习网络的模型参数;Initialize the model parameters of the initial deep learning network;
通过坐标转换卷积模块对训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据;Use the coordinate conversion convolution module to perform convolution operation on the sample sample data in the training sample to obtain the under-sampled non-uniform sample data in the Cartesian coordinate system;
通过密度补偿卷积模块对笛卡尔坐标系下的欠采样非均匀样本数据进行密度补偿,生成对应的欠采样均匀样本数据;Perform density compensation on the under-sampled non-uniform sample data in the Cartesian coordinate system through the density compensation convolution module to generate corresponding under-sampled uniform sample data;
通过图像重建卷积模块对欠采样均匀样本数据进行卷积运算,生成欠采样均匀样本数据对应的预测图像;Perform convolution operation on the under-sampled uniform sample data through the image reconstruction convolution module to generate the predicted image corresponding to the under-sampled uniform sample data;
若当前不满足预设条件,则更新当前深度学习网络的模型参数,并返回执行通过坐标转换卷积模块对训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据的步骤;若满足预设条件,保存当前的模型参数,获得深度学习网络。If the preset conditions are not currently met, update the model parameters of the current deep learning network, and return to perform the convolution operation of the sample sampling data in the training sample through the coordinate conversion convolution module to obtain the under-sampling non-uniformity in the Cartesian coordinate system The step of sample data; if the preset conditions are met, the current model parameters are saved to obtain the deep learning network.
在第一方面的一种可能的实现方式中,预设采样模式包括径向采样或螺旋扫描采样。In a possible implementation of the first aspect, the preset sampling mode includes radial sampling or spiral scanning sampling.
第二方面,本申请实施例提供了一种图像重建装置,包括:In the second aspect, an embodiment of the present application provides an image reconstruction device, including:
采样模块,用于获取目标对象的采样数据;其中,采样数据为基于预设采样模式获取的非笛卡尔坐标系下的欠采样频域数据;The sampling module is used to obtain sampling data of the target object; wherein, the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system obtained based on a preset sampling mode;
重建模块,用于将采样数据输入训练后的深度学习网络进行处理,获得采样数据对应的重建图像;其中,深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及成像目标的全采样样本图像,对初始深度学习网络训练得到。The reconstruction module is used to input the sampled data into the trained deep learning network for processing to obtain the reconstructed image corresponding to the sampled data; among them, the deep learning network is based on the frequency domain of under-sampled samples in a non-Cartesian coordinate system of multiple imaging targets The data and the fully sampled sample images of the imaging target are obtained by training the initial deep learning network.
第三方面,本申请实施例提供了一种图像重建设备,包括存储器、处理器以及 存储在存储器中并可在处理器上运行的计算机可读指令,处理器执行计算机可读指令时实现上述第一方面任一项方法的步骤。In a third aspect, an embodiment of the present application provides an image reconstruction device, including a memory, a processor, and computer-readable instructions stored in the memory and running on the processor. The processor executes the computer-readable instructions to implement the above-mentioned first On the one hand, the steps of any method.
第四方面,本申请实施例提供了一种计算机可读存储介质,计算机可读存储介质存储有计算机可读指令,计算机可读指令被处理器执行时实现上述第一方面任一项方法的步骤。In a fourth aspect, the embodiments of the present application provide a computer-readable storage medium, the computer-readable storage medium stores computer-readable instructions, and the computer-readable instructions implement the steps of any one of the methods in the first aspect when the computer-readable instructions are executed by a processor. .
第五方面,本申请实施例提供了一种计算机程序产品,当计算机程序产品在图像重建设备上运行时,使得图像重建设备执行上述第一方面中任一项的方法。In a fifth aspect, embodiments of the present application provide a computer program product, which when the computer program product runs on an image reconstruction device, causes the image reconstruction device to execute the method in any one of the above-mentioned first aspects.
本申请实施例与现有技术相比存在的有益效果是:通过训练后的深度学习网络,对目标对象的采样数据进行处理,从而得到采样数据对应的重建图像,实现了目标对象采样数据的图像重建;其中,采样数据为非笛卡尔坐标系下的欠采样频域数据,深度学习网络为基于多个成像目标的欠采样样本频域数据以及该成像目标的全采样样本图像,对初始深度学习网络训练得到的。相比于现有技术中基于非均匀快速傅里叶变换对非笛卡尔坐标系下的欠采样频域数据进行图像重建的技术方案,本申请实施例中深度学习网络经过预先训练,可以直接根据输入的采样数据,获得对应的重建图形,不需要人工选择/调整尺度因子等参数,提高了非笛卡尔坐标系下的欠采样频域数据的重建速度;另一方面,本申请中深度学习网络可以直接基于图形处理器GPU进行加速计算,在保障图像重建精度的前提下,进一步地缩短了非笛卡尔坐标系下的欠采样频域数据的图像重建时间。Compared with the prior art, the embodiment of the present application has the beneficial effect that the sampled data of the target object is processed through the trained deep learning network, thereby obtaining the reconstructed image corresponding to the sampled data, and realizing the image of the sampled data of the target object Reconstruction; where the sampled data is the under-sampled frequency domain data in a non-Cartesian coordinate system, and the deep learning network is based on the under-sampled sample frequency domain data of multiple imaging targets and the fully sampled sample image of the imaging target, and the initial deep learning Obtained from network training. Compared with the prior art technical solution for image reconstruction based on non-uniform fast Fourier transform for under-sampled frequency domain data in a non-Cartesian coordinate system, the deep learning network in the embodiment of the application is pre-trained and can be directly based on The input sampling data obtains the corresponding reconstruction graph without manual selection/adjustment of parameters such as scale factors, which improves the reconstruction speed of the under-sampled frequency domain data in the non-Cartesian coordinate system; on the other hand, the deep learning network in this application Accelerated calculations can be performed directly based on the graphics processor GPU. Under the premise of ensuring the accuracy of image reconstruction, the image reconstruction time of under-sampling frequency domain data in the non-Cartesian coordinate system is further shortened.
可以理解的是,上述第二方面至第五方面的有益效果可以参见上述第一方面中的相关描述,在此不再赘述。It can be understood that, for the beneficial effects of the second aspect to the fifth aspect described above, reference may be made to the related description in the first aspect described above, and details are not repeated here.
发明的有益效果The beneficial effects of the invention
对附图的简要说明Brief description of the drawings
附图说明Description of the drawings
为了更清楚地说明本申请实施例中的技术方案,下面将对实施例或示范性技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本申请的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其它的附图。In order to more clearly describe the technical solutions in the embodiments of the present application, the following will briefly introduce the accompanying drawings that need to be used in the embodiments or exemplary technical descriptions. Obviously, the accompanying drawings in the following description are only of the present application. For some embodiments, those of ordinary skill in the art can obtain other drawings based on these drawings without creative work.
为了更清楚地说明本申请实施例中的技术方案,下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本申请的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。In order to more clearly describe the technical solutions in the embodiments of the present application, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only of the present application. For some embodiments, those of ordinary skill in the art can obtain other drawings based on these drawings without creative work.
图1是本申请一实施例提供的图像重建系统的架构示意图;FIG. 1 is a schematic diagram of the architecture of an image reconstruction system provided by an embodiment of the present application;
图2是本申请一实施例提供的图像重建方法的流程示意图;FIG. 2 is a schematic flowchart of an image reconstruction method provided by an embodiment of the present application;
图3是本申请一实施例提供的深度学习网络的架构示意图;FIG. 3 is a schematic diagram of the architecture of a deep learning network provided by an embodiment of the present application;
图4是本申请一实施例提供的获得采样数据对应的重建图像的流程示意图;FIG. 4 is a schematic diagram of a process of obtaining a reconstructed image corresponding to sampling data according to an embodiment of the present application;
图5是本申请一实施例提供的获取训练后的深度学习网络的流程示意图;FIG. 5 is a schematic diagram of a process of acquiring a trained deep learning network provided by an embodiment of the present application;
图6是本申请一实施例提供的获取训练样本的流程示意图;FIG. 6 is a schematic diagram of a process of obtaining training samples provided by an embodiment of the present application;
图7是本申请一实施例提供的对深度学习网络进行迭代训练的流程示意图;FIG. 7 is a schematic diagram of a process flow for iterative training of a deep learning network provided by an embodiment of the present application;
图8是本申请一实施例提供的图像重建装置的组成示意图;FIG. 8 is a schematic diagram of the composition of an image reconstruction device provided by an embodiment of the present application;
图9是本申请另一实施例提供的图像重建装置的组成示意图;FIG. 9 is a schematic diagram of the composition of an image reconstruction device provided by another embodiment of the present application;
图10是本申请一实施例提供的图像重建设备的结构示意图。FIG. 10 is a schematic structural diagram of an image reconstruction device provided by an embodiment of the present application.
发明实施例Invention embodiment
本发明的实施方式Embodiments of the present invention
为了能够更加详尽地了解本申请实施例的特点与技术内容,下面结合附图对本申请实施例的实现进行详细阐述,所附附图仅供参考说明之用,并非用来限定本申请实施例。在以下的技术描述中,为方便解释起见,通过多个细节以提供对所披露实施例的充分理解。然而,在没有这些细节的情况下,一个或多个实施例仍然可以实施。在其它情况下,为简化附图,熟知的结构和装置可以简化展示。In order to have a more detailed understanding of the characteristics and technical content of the embodiments of the present application, the implementation of the embodiments of the present application will be described in detail below with reference to the accompanying drawings. The attached drawings are for reference and explanation purposes only, and are not used to limit the embodiments of the present application. In the following technical description, for the convenience of explanation, a number of details are used to provide a sufficient understanding of the disclosed embodiments. However, without these details, one or more embodiments can still be implemented. In other cases, in order to simplify the drawings, well-known structures and devices may be simplified for display.
应当理解,当在本申请说明书和所附权利要求书中使用时,术语“包括”指示所描述特征、整体、步骤、操作、元素和/或组件的存在,但并不排除一个或多个其它特征、整体、步骤、操作、元素、组件和/或其集合的存在或添加。It should be understood that when used in the specification and appended claims of this application, the term "comprising" indicates the existence of the described features, wholes, steps, operations, elements and/or components, but does not exclude one or more other The existence or addition of features, wholes, steps, operations, elements, components, and/or collections thereof.
另外,在本申请说明书和所附权利要求书的描述中,术语“第一”、“第二”等仅用于区分描述,而不能理解为指示或暗示相对重要性。In addition, in the description of the specification of this application and the appended claims, the terms "first", "second", etc. are only used to distinguish the description, and cannot be understood as indicating or implying relative importance.
图1为本申请一实施例提供的图像重建系统的架构示意图,如图1所示,图像重 建系统包括图像采集设备10和图像重建设备20。FIG. 1 is a schematic diagram of the architecture of an image reconstruction system provided by an embodiment of the application. As shown in FIG. 1, the image reconstruction system includes an image acquisition device 10 and an image reconstruction device 20. As shown in FIG.
图像采集设备10是指用于向用户提供医学影像成像的设备。例如,磁共振设备。The image acquisition device 10 refers to a device for providing medical imagery to users. For example, magnetic resonance equipment.
图像采集设备10可以根据采样模式不同,获得不同的采样数据,包括但不限于非均匀的欠采样频域数据、均匀的欠采样频域数据、均匀的全采样频域数据等。例如,当采样模式为螺旋扫描采样时,采样数据为非笛卡尔坐标系下的非均匀欠采样频域数据。The image acquisition device 10 can obtain different sampling data according to different sampling modes, including but not limited to non-uniform under-sampling frequency domain data, uniform under-sampling frequency domain data, uniform full-sampling frequency domain data, and the like. For example, when the sampling mode is spiral scanning sampling, the sampling data is non-uniform under-sampling frequency domain data in a non-Cartesian coordinate system.
图像重建设备20用于接收图像采集设备10发送的非笛卡尔坐标系下的采样数据,以进行图像重建。图像重建设备20通过网络与图像采集设备10进行通信。上述网络包括但不限于广域网、局域网。The image reconstruction device 20 is configured to receive sampling data in a non-Cartesian coordinate system sent by the image acquisition device 10 to perform image reconstruction. The image reconstruction device 20 communicates with the image acquisition device 10 through a network. The aforementioned networks include, but are not limited to, wide area networks and local area networks.
图像重建设备20可以为云端服务器,云端服务器可以是实现单一功能的服务器,也可以是实现多种功能的服务器,具体可以是独立的物理服务器,也可以是物理服务器集群。The image reconstruction device 20 may be a cloud server. The cloud server may be a server that implements a single function or a server that implements multiple functions. Specifically, it may be an independent physical server or a cluster of physical servers.
示例性的,假设本申请实施例提供的图像重建方法由图像重建设备20执行,图像采集设备10为磁共振设备。磁共振设备将采样点按预设的编排方式进行存放,生成采样数据,并将采样数据发送至图像重建设备20,由图像重建设备20进行后续的图像重建。Illustratively, it is assumed that the image reconstruction method provided in the embodiment of the present application is executed by the image reconstruction device 20, and the image acquisition device 10 is a magnetic resonance device. The magnetic resonance equipment stores the sampling points in a preset arrangement, generates sampling data, and sends the sampling data to the image reconstruction device 20, and the image reconstruction device 20 performs subsequent image reconstruction.
编排方式由采样模式确定。实际应用中,若磁共振设备采用直线式扫描采样,采样点均匀分布在网格点上。图像重建设备20经过傅里叶逆变换就可以得到二维平面内每个确定位置体素的信号强度,将其转换为相应的灰度值,就得到磁共振图像。The arrangement method is determined by the sampling mode. In practical applications, if the magnetic resonance equipment adopts linear scanning sampling, the sampling points are evenly distributed on the grid points. The image reconstruction device 20 can obtain the signal intensity of each voxel at a certain position in the two-dimensional plane through the inverse Fourier transform, and convert it into the corresponding gray value to obtain the magnetic resonance image.
但是直线式采样的成像速度较慢,限制了磁共振设备在临床医学影像领域的应用发展,为了提高成像效率,可以采用螺旋轨迹进行扫描采样。采用螺旋轨迹扫描采样后,采样点位于极坐标平面(非笛卡尔坐标系)上的一系列螺旋轨迹上,不是规则的矩形网格点,如果直接对螺旋轨迹扫描获取的采样点进行图像重建,需要预先进行网格化处理以及采用窗函数(尺度因子)进行平滑处理,需要非常大的计算量。However, the imaging speed of linear sampling is slow, which limits the application and development of magnetic resonance equipment in the field of clinical medical imaging. In order to improve imaging efficiency, spiral trajectories can be used for scanning and sampling. After sampling with spiral trajectory scanning, the sampling points are located on a series of spiral trajectories on the polar coordinate plane (non-Cartesian coordinate system). They are not regular rectangular grid points. If you directly reconstruct the image of the sampling points obtained by spiral trajectory scanning, It is necessary to perform grid processing in advance and use window functions (scale factors) for smoothing processing, which requires a very large amount of calculation.
本申请实施例提供的图像重建方法中,图像重建设备20获取磁共振设备10采集 的非笛卡尔坐标系下的欠采样数据,将该非笛卡尔坐标系下的欠采样数据输入训练后的深度学习网络进行重建处理,直接获得目标对象的重建图像。In the image reconstruction method provided by the embodiment of the application, the image reconstruction device 20 obtains the under-sampling data in the non-Cartesian coordinate system collected by the magnetic resonance device 10, and inputs the under-sampling data in the non-Cartesian coordinate system to the depth after training The learning network performs reconstruction processing and directly obtains the reconstructed image of the target object.
为使本发明实施例的目的、技术方案和优点更加清楚,下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行示例性地描述,显然,所描述的实施例是本发明一部分实施例,而不是全部的实施例。基于下文中列举的实施例,本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。In order to make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the following will exemplarily describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are A part of the embodiments of the present invention, but not all the embodiments. Based on the embodiments listed below, all other embodiments obtained by a person of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.
图2为本申请一实施例提供的图像重建方法的流程示意图,本图像重建方法的执行主体为图1中所示的图像重建设备,如图2所示,该图像重建方法包括:Fig. 2 is a schematic flowchart of an image reconstruction method provided by an embodiment of the application. The image reconstruction method is executed by the image reconstruction device shown in Fig. 1. As shown in Fig. 2, the image reconstruction method includes:
S201、获取目标对象的采样数据;其中,采样数据为基于预设采样模式获取的非笛卡尔坐标系下的欠采样频域数据;S201. Acquire sampling data of the target object; where the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system acquired based on a preset sampling mode;
在本实施例中,目标对象是通过医学成像设备进行检测的检体。示例性的,目标对象包括仿体、活体(动物或人体)、离体器官或组织等。In this embodiment, the target object is a specimen to be detected by a medical imaging device. Exemplarily, the target object includes a simulation body, a living body (animal or human body), an isolated organ or tissue, and the like.
在本实施例中,预设采样模式采集到的数据可以为非笛卡尔坐标系的数据;预设采样模式中采样点投影到笛卡尔坐标系后,相邻的两个采样点之间的间隔可以不均匀。例如:预设采样模式可以包括下述任意一种:径向采样、螺旋轨迹采样、旋转扫描采样、基于平面回波成像序列(echo planar imaging,EPI)采样以及步进式(interleave)采样。其中EPI是在一次脉冲激发后依靠梯度线圈的连续反方向切换,采集一连串梯度回波信号。In this embodiment, the data collected by the preset sampling mode may be data in a non-Cartesian coordinate system; after the sampling point in the preset sampling mode is projected to the Cartesian coordinate system, the interval between two adjacent sampling points It can be uneven. For example, the preset sampling mode may include any one of the following: radial sampling, spiral trajectory sampling, rotating scan sampling, echo planar imaging (EPI) based sampling, and interleave sampling. Among them, EPI relies on the continuous reverse direction switching of the gradient coil after a pulse excitation to collect a series of gradient echo signals.
示例性的,假设预设采样模式为磁共振设备基于螺旋轨迹对目标对象进行扫描。螺旋轨迹扫描一般从采样点存放空间的中央出发,然后呈螺旋状向外扩展。也就是说,一次激发后的采样点不是在二维的网格上顺序排列的,通过调节梯度波形,使得数据沿着螺旋轨迹加以填充,采用螺旋轨迹扫描成像后,各采样点位于极坐标平面(非笛卡尔坐标系)上的一系列螺旋轨迹上,不是规则的矩形网格点;将采样点投影到笛卡尔坐标系后,相邻的采样点之间的间隔不相同。磁共振设备将位于极坐标平面的一系列的初始采样点发送至图像重建设备,以使图像重建设备对该数据进行图像重建,获得目标对象的重建图像。Exemplarily, it is assumed that the preset sampling mode is that the magnetic resonance device scans the target object based on the spiral trajectory. Spiral trajectory scanning generally starts from the center of the storage space of the sampling point, and then expands outward in a spiral shape. That is to say, the sampling points after one excitation are not arranged sequentially on a two-dimensional grid. By adjusting the gradient waveform, the data is filled along the spiral trajectory. After the spiral trajectory is used for scanning and imaging, each sampling point is located in the polar coordinate plane. A series of spiral trajectories on (non-Cartesian coordinate system) are not regular rectangular grid points; after the sampling points are projected to the Cartesian coordinate system, the intervals between adjacent sampling points are not the same. The magnetic resonance device sends a series of initial sampling points located on the polar coordinate plane to the image reconstruction device, so that the image reconstruction device performs image reconstruction on the data to obtain a reconstructed image of the target object.
S202、将采样数据输入训练后的深度学习网络进行处理,获得采样数据对应的 重建图像;其中,深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及成像目标的全采样样本图像,对初始深度学习网络训练得到。S202. Input the sampled data into the trained deep learning network for processing, and obtain a reconstructed image corresponding to the sampled data; wherein, the deep learning network is based on the under-sampled sample frequency domain data in the non-Cartesian coordinate system of multiple imaging targets and imaging The fully sampled sample image of the target is obtained by training the initial deep learning network.
本实施例中的深度学习网络为基于深度学习框架构建的深度学习网络。该深度学习网络的输入为非笛卡尔坐标系下的欠采样样本频域数据,输出为接近全采样的高精度的图像,即重建图像。The deep learning network in this embodiment is a deep learning network constructed based on a deep learning framework. The input of the deep learning network is frequency-domain data of under-sampled samples in a non-Cartesian coordinate system, and the output is a high-precision image close to full sampling, that is, a reconstructed image.
本实施例中,可以多个预设采样模式对应一个深度学习网络,也可以每个预设采样模型对应一个深度学习网络,应根据预设采样模式中采样原理进行划分,在此不做限定。In this embodiment, multiple preset sampling modes may correspond to one deep learning network, or each preset sampling model may correspond to one deep learning network. The division should be based on the sampling principle in the preset sampling mode, which is not limited here.
深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及成像目标的全采样样本图像,对初始深度学习网络训练得到。在训练过程中,成像目标的非笛卡尔坐标系下的欠采样样本频域数据是采用预设采样模式获取得到,全采样样本图像用于与初始深度学习网络输出的预测图像进行比较,以基于比较结果调整初始深度学习网络的模型参数。The deep learning network is based on the under-sampled sample frequency domain data in the non-Cartesian coordinate system of multiple imaging targets and the fully sampled sample image of the imaging target, which is obtained by training the initial deep learning network. During the training process, the frequency domain data of the under-sampled samples in the non-Cartesian coordinate system of the imaging target is obtained by using a preset sampling mode. The full-sampled sample image is used to compare with the predicted image output by the initial deep learning network to be based on The comparison result adjusts the model parameters of the initial deep learning network.
本实施例中,深度学习网络包括级联的依次级联的坐标转换卷积模块、密度补偿卷积模块以及图像重建卷积模块。其中,坐标转换卷积模块,用于接收输入的非笛卡尔坐标系下欠采样频域数据,并对非笛卡尔坐标系下的欠采样频域数据进行卷积运算得到笛卡尔坐标系下的欠采样均匀频域数据。密度补偿卷积模块用于对笛卡尔坐标系下的欠采样非均匀频域数据进行密度补偿处理,得到笛卡尔坐标系下的欠采样均匀频域数据。图像重建卷积模块,用于对欠采样均匀频域数据进行重建处理,得到欠采样均匀频域数据对应的重建图像。In this embodiment, the deep learning network includes a cascaded coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module that are sequentially cascaded. Among them, the coordinate conversion convolution module is used to receive the input under-sampled frequency domain data in a non-Cartesian coordinate system, and perform convolution operations on the under-sampled frequency-domain data in a non-Cartesian coordinate system to obtain the under-sampled frequency domain data in the non-Cartesian coordinate system. Undersample uniform frequency domain data. The density compensation convolution module is used to perform density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system. The image reconstruction convolution module is used to reconstruct the under-sampled uniform frequency domain data to obtain the reconstructed image corresponding to the under-sampled uniform frequency domain data.
请一并参阅图3,图3主要针对S202中如何获得采样数据对应的重建图像进行示例性描述。假设预设的采样模式为螺旋轨迹采样。Please refer to FIG. 3 together. FIG. 3 mainly describes how to obtain the reconstructed image corresponding to the sampling data in S202. Assume that the preset sampling mode is spiral trajectory sampling.
如图3所示,将采样数据输入训练后的深度学习网络进行处理,获得采样数据对应的重建图像,包括S2011~S2013,具体如下:As shown in Figure 3, the sampled data is input into the trained deep learning network for processing, and the reconstructed image corresponding to the sampled data is obtained, including S2011 to S2013, as follows:
S2021、将采样数据输入训练后的深度学习网络进行坐标转换,得到采样数据对应的笛卡尔坐标系下的欠采样非均匀频域数据。S2021: Input the sampled data into the trained deep learning network to perform coordinate conversion, and obtain the under-sampled non-uniform frequency domain data in the Cartesian coordinate system corresponding to the sampled data.
坐标转换卷积模块,接收输入采样数据,即非笛卡尔坐标系下的欠采样频域数 据,对该非笛卡尔坐标系下的欠采样频域数据进行卷积运算得到笛卡尔坐标系下的欠采样均匀频域数据。The coordinate conversion convolution module receives the input sampling data, that is, the under-sampled frequency domain data in the non-Cartesian coordinate system, and performs convolution operation on the under-sampled frequency domain data in the non-Cartesian coordinate system to obtain the data in the Cartesian coordinate system. Undersample uniform frequency domain data.
其中,卷积运算可以为实数卷积运算也可以为复数卷积运算。在一种实施方式中,坐标转换卷积模块进行复数卷积运算,坐标转换卷积模块包括多层级联的第一复数卷积块。Among them, the convolution operation may be a real number convolution operation or a complex number convolution operation. In an embodiment, the coordinate transformation convolution module performs complex convolution operations, and the coordinate transformation convolution module includes a first complex convolution block cascaded in multiple layers.
第一复数卷积块的复数卷积运算可以表示为:The complex convolution operation of the first complex convolution block can be expressed as:
W*C=(A+iB)*(a+ib)=(Aa-Bb)+i(Ab+Ba)    (1)W*C=(A+iB)*(a+ib)=(Aa-Bb)+i(Ab+Ba) (1)
其中,W表示输入的采样数据,A表示采样数据的实部,B表示采样数据的虚部,C表示复数卷积核,a表示复数卷积核的实部,b表示复数卷积核的虚部,对采样数据的实部和虚部分别进行卷积。Among them, W represents the input sampled data, A represents the real part of the sampled data, B represents the imaginary part of the sampled data, C represents the complex convolution kernel, a represents the real part of the complex convolution kernel, and b represents the imaginary part of the complex convolution kernel. Part, convolve the real and imaginary parts of the sampled data respectively.
S2022、对笛卡尔坐标系下的欠采样非均匀频域数据进行密度补偿处理,得到笛卡尔坐标系下的欠采样均匀频域数据。S2022 Perform density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system.
密度补偿卷积模块包括多层级联的第二复数卷积块。多层第二复数卷积块依次通过复数卷积运算实现对欠采样非均匀频域数据进行密度补偿处理。复数卷积运算同上式(1),在此不再赘述。The density compensation convolution module includes a second complex convolution block cascaded in multiple layers. The multi-layer second complex convolution block sequentially implements a complex convolution operation to perform density compensation processing on the under-sampled non-uniform frequency domain data. The complex convolution operation is the same as the above formula (1), and will not be repeated here.
S2023、对欠采样均匀频域数据进行重建处理,得到欠采样均匀频域数据对应的重建图像。S2023: Perform reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
图像重建卷积模块,对欠采样均匀频域数据进行填充处理,得到全采样的均匀频域数据;然后对均匀频域数据进行傅里叶逆变换,得到欠采样均匀频域数据对应的重建图像。Image reconstruction convolution module, fills the under-sampled uniform frequency domain data to obtain fully sampled uniform frequency domain data; then performs inverse Fourier transform on the uniform frequency domain data to obtain the reconstructed image corresponding to the under-sampled uniform frequency domain data .
图像重建卷积模块包括多层级联的第三复数卷积块,多层第三复数卷积块依次通过复数卷积运算实现对欠采样均匀频域数据进行填充处理。复数卷积运算同上式(1),在此不再赘述。从信号与图像处理的角度来说,复数与实数相比引入了相位信息,图像的相位信息提供了图像形状、边缘和方向的细节性描述,可用于恢复图像的幅度信息,基于复数卷积运算的深度学习网络,具有更好的图像重建效果。The image reconstruction convolution module includes a multi-layer cascaded third complex convolution block, and the multi-layer third complex convolution block sequentially implements the filling process of the under-sampled uniform frequency domain data through the complex convolution operation. The complex convolution operation is the same as the above formula (1), and will not be repeated here. From the perspective of signal and image processing, complex numbers introduce phase information compared to real numbers. The phase information of the image provides a detailed description of the shape, edge and direction of the image, which can be used to restore the amplitude information of the image, based on complex convolution operations. The deep learning network has better image reconstruction effects.
本实施例中,重建图像的精度受第一复数卷积块、第二复数卷积块以及第三复数卷积块中卷积核的大小影响,可以根据重建图像的精度需求设置卷积核的大 小,在此不做具体限定。In this embodiment, the accuracy of the reconstructed image is affected by the size of the convolution kernel in the first complex convolution block, the second complex convolution block, and the third complex convolution block. The convolution kernel can be set according to the accuracy requirements of the reconstructed image. The size is not limited here.
示例性的,请一并参阅图4,图4为本申请实施例提供的深度学习网络的结构示意图,如图4所示,深度学习网络包括级联的依次级联的坐标转换卷积模块、密度补偿卷积模块以及图像重建卷积模块,坐标转换卷积模块的输入为采样数据,输出为笛卡尔坐标系下的欠采样非均匀频域数据;密度补偿卷积模块的输入为欠采样频域数据,输出为笛卡尔坐标系下的欠采样均匀频域数据,图像重建卷积模块的输入为欠采样均匀频域数据,输出为重建图像。Exemplarily, please refer to FIG. 4 together. FIG. 4 is a schematic structural diagram of a deep learning network provided by an embodiment of the application. As shown in FIG. 4, the deep learning network includes cascaded coordinate conversion convolution modules that are sequentially cascaded, Density compensation convolution module and image reconstruction convolution module. The input of the coordinate conversion convolution module is sampled data, and the output is under-sampling non-uniform frequency domain data in Cartesian coordinates; the input of the density compensation convolution module is under-sampling frequency Domain data, the output is the under-sampled uniform frequency domain data in the Cartesian coordinate system, the input of the image reconstruction convolution module is the under-sampled uniform frequency domain data, and the output is the reconstructed image.
其中,坐标转换卷积模块包括多层级联的第一复数卷积块。密度补偿卷积模块包括多层级联的第二复数卷积块;图像重建卷积模块包括多层级联的第三复数卷积块。Wherein, the coordinate conversion convolution module includes a first complex convolution block cascaded in multiple layers. The density compensation convolution module includes a multi-layer cascaded second complex convolution block; the image reconstruction convolution module includes a multi-layer cascaded third complex convolution block.
实际应用中,坐标转换卷积模块接收非笛卡尔坐标系下的欠采样频域数据,级联的第一复数卷积块依次对该非笛卡尔坐标系下的欠采样频域数据进行复数卷积运算,即上一个第一复数卷积块的输出为下一个第一复数卷积块的输入,直至多个第一复数卷积模块均完成复数卷积运算,生成笛卡尔坐标系下的欠采样频域数据;多层级联的第二复数卷积块中第一个第二复数卷积块接收最后一个第一复数卷积块的输出(即笛卡尔坐标系下的欠采样频域数据),并对该输出进行复数卷积运算,然后级联的第二复数卷积块依次对上一个第二复数卷积块的输出进行复数卷积运算,直至输出笛卡尔坐标系下的欠采样均匀频域数据;In practical applications, the coordinate conversion convolution module receives the under-sampled frequency domain data in a non-Cartesian coordinate system, and the cascaded first complex convolution block sequentially performs complex convolutions on the under-sampled frequency domain data in the non-Cartesian coordinate system. Product operation, that is, the output of the previous first complex convolution block is the input of the next first complex convolution block, until multiple first complex convolution modules have completed the complex convolution operation to generate the undercartesian coordinate system Sampling frequency domain data; the first second complex convolution block in the second complex convolution block of multi-layer cascade receives the output of the last first complex convolution block (that is, the under-sampled frequency domain data in the Cartesian coordinate system) , And perform complex convolution operations on the output, and then the cascaded second complex convolution block sequentially performs complex convolution operations on the output of the previous second complex convolution block, until the output under-sampling in the Cartesian coordinate system is uniform Frequency domain data;
级联的第三复数卷积块依次对该欠采样均匀频域数据进行复数卷积运算,即上一个第三复数卷积块的输出为下一个第三复数卷积块的输入,直至多个第三复数卷积块均完成复数卷积运算,输出重建图像。The cascaded third complex convolution block sequentially performs complex convolution operations on the under-sampled uniform frequency domain data, that is, the output of the previous third complex convolution block is the input of the next third complex convolution block, up to multiple The third complex convolution block all completes the complex convolution operation and outputs the reconstructed image.
本实施例提供的图像重建方法,本申请实施例与现有技术相比存在的有益效果是:通过训练后的深度学习网络,对目标对象的采样数据进行处理,从而得到采样数据对应的重建图像,实现了目标对象采样数据的图像重建;其中,采样数据为非笛卡尔坐标系下的欠采样频域数据,深度学习网络为基于多个成像目标的欠采样样本频域数据以及该成像目标的全采样样本图像,对初始深度学习网络训练得到的。相比于现有技术中基于非均匀快速傅里叶变换对非笛卡尔坐标系下的欠采样频域数据进行图像重建的技术方案,本申请实施例中深度学习 网络经过预先训练,可以直接根据输入的采样数据,获得对应的重建图形,不需要人工选择/调整尺度因子等参数,提高了非笛卡尔坐标系下的欠采样频域数据的重建速度;另一方面,本申请中深度学习网络可以直接基于图形处理器GPU进行加速计算,在保障图像重建精度的前提下,进一步地缩短了非笛卡尔坐标系下的欠采样频域数据的图像重建时间Compared with the prior art, the advantageous effect of the image reconstruction method provided in this embodiment is that the sampled data of the target object is processed through the trained deep learning network, so as to obtain the reconstructed image corresponding to the sampled data. , The image reconstruction of the sampled data of the target object is realized; among them, the sampled data is the under-sampled frequency domain data in a non-Cartesian coordinate system, and the deep learning network is based on the under-sampled sample frequency domain data of multiple imaging targets and the imaging target's image reconstruction. Fully sampled sample images, obtained by training the initial deep learning network. Compared with the prior art technical solution for image reconstruction based on non-uniform fast Fourier transform for under-sampled frequency domain data in a non-Cartesian coordinate system, the deep learning network in the embodiment of the application is pre-trained and can be directly based on The input sampling data obtains the corresponding reconstruction graph without manual selection/adjustment of parameters such as scale factors, which improves the reconstruction speed of the under-sampled frequency domain data in the non-Cartesian coordinate system; on the other hand, the deep learning network in this application Accelerated calculations can be directly based on the graphics processor GPU. Under the premise of ensuring the accuracy of image reconstruction, the image reconstruction time of under-sampling frequency domain data in non-Cartesian coordinates is further shortened.
请一并参阅图5,图5为本申请一实施例提供的获取训练后的深度学习网络的流程示意图,图5主要针对如何获取步骤S202中训练后的深度学习网络进行示例性描述。如图5所示,获取训练后的深度学习网络的方法包括S501~S502,具体如下:Please refer to FIG. 5 together. FIG. 5 is a schematic diagram of a process for obtaining a trained deep learning network according to an embodiment of the application. FIG. 5 mainly describes how to obtain the trained deep learning network in step S202. As shown in Figure 5, the method for obtaining the trained deep learning network includes S501 to S502, which are specifically as follows:
S501、获取多个训练样本,每个训练样本包括成像目标的全采样样本图像和基于预设采样模式对成像目标进行处理获得的样本采样数据;全采样样本图像用于与初始深度学习网络输出的预测图像进行比较;预设采样模式中相邻的两个采样点之间的间隔不均匀。S501. Obtain a plurality of training samples, each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on a preset sampling mode; the fully sampled sample image is used for output from the initial deep learning network The predicted images are compared; the interval between two adjacent sampling points in the preset sampling mode is not uniform.
多个训练样本对应于多个成像目标,训练样本与成像目标一一对应,成像目标可以包括步骤202中目标对象,是用于通过医学成像设备进行检测的检体。成像目标可以指一个目标检体上的不同位置的对象,也可以指不同的目标检体。The multiple training samples correspond to multiple imaging targets, and the training samples correspond to the imaging targets on a one-to-one basis. The imaging targets may include the target object in step 202, which is a specimen used for detection by a medical imaging device. The imaging target may refer to objects at different positions on a target specimen, or may refer to different target specimens.
成像目标的全采样样本图像可以基于低倍欠采因子从医学影像设备采集获得。The fully sampled sample image of the imaging target can be acquired from a medical imaging device based on a low-power under-sampling factor.
每个训练样本中的样本采样数据可以基于预设采样模式对成像目标进行处理获得。The sample sampling data in each training sample can be obtained by processing the imaging target based on a preset sampling mode.
请一并参阅图6,图6主要针对上述S501中如何获取训练样本进行示例性描述。成像目标有多个,多个训练样本对应于多个成像目标。Please refer to FIG. 6 together. FIG. 6 mainly describes how to obtain training samples in the foregoing S501. There are multiple imaging targets, and multiple training samples correspond to multiple imaging targets.
如图6所示,获取多个训练样本的步骤包括S5011~S5013,具体如下:As shown in Figure 6, the steps of obtaining multiple training samples include S5011 to S5013, which are specifically as follows:
S5011、获取每个成像目标对应的全采样样本图像,全采样样本图像由医学影像设备采集。S5011. Obtain a full-sampling sample image corresponding to each imaging target, and the full-sampling sample image is collected by the medical imaging equipment.
本实施例中,医院影像设备可以为磁共振设备,磁共振设备可以基于低倍欠采因子从磁共振设备上采集获得成像目标扫描图像,然后对采集获得的扫描图像进行预处理,并将处理后的图像作为成像目标的全采样样本图像。其中,预处理方式可以包括选图处理、归一化处理等。选图处理用于取出一些质量不高或 者包含较多噪音数据的图像,以提高训练的效率。归一化处理是为了更便于进行该全采样图像在复数卷积神经网络中的输入,以适应后续的训练。In this embodiment, the hospital imaging equipment may be a magnetic resonance equipment, and the magnetic resonance equipment may acquire a scan image of the imaging target from the magnetic resonance equipment based on a low-power under-collection factor, and then preprocess the acquired scan image and process it The latter image is used as a fully sampled sample image of the imaging target. Among them, the preprocessing method can include image selection processing, normalization processing, and so on. Image selection processing is used to extract some images with low quality or with more noise data to improve the efficiency of training. The normalization process is to facilitate the input of the fully sampled image in the complex convolutional neural network to adapt to subsequent training.
S5012、基于预设采样模式获取每个成像目标的样本采样数据,样本采样数据为非笛卡尔坐标系下的欠采样频域数据。S5012: Acquire sample sampling data of each imaging target based on a preset sampling mode, where the sample sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system.
针对某一成像目标,基于预设采样模式从同一个磁共振设备上采集获得其的初始欠采样频域数据,即未成像前的频域数据,该成像目标为在非笛卡尔坐标系下的欠采样样本频域数据。For a certain imaging target, the initial under-sampling frequency domain data is acquired from the same MRI device based on the preset sampling mode, that is, the frequency domain data before imaging. The imaging target is in a non-Cartesian coordinate system. Frequency domain data of under-sampled samples.
S5013、将每个成像目标对应的全采样样本图像和样本采样数据作为一个训练样本。S5013. Use the fully sampled sample image and sample sample data corresponding to each imaging target as a training sample.
将其全采样图像和欠采样频域数据组合为一个训练样本。Combine its fully sampled image and undersampled frequency domain data into a training sample.
本实施例提供的获取多个训练样本,对基于医学成像设备获得的成像目标的全采样初始扫描图像进行预处理,获得成像目标的全采样图像,部分消除了奇异样本数据导致的不良影响,提高训练的效率。The acquisition of multiple training samples provided by this embodiment preprocesses the fully sampled initial scan image of the imaging target obtained by the medical imaging equipment to obtain the fully sampled image of the imaging target, which partially eliminates the adverse effects caused by singular sample data and improves Training efficiency.
S502、根据多个训练样本,对初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络。S502: Perform iterative training on the initial deep learning network according to multiple training samples, and stop training when a preset condition is met, to obtain a trained deep learning network.
在本实施例中,初始深度学习网络的结构与步骤202中的深度学习网络结构相同。初始深度学习网络包括级联的坐标转换卷积模块、密度补偿卷积模块以及图像重建卷积模块。In this embodiment, the structure of the initial deep learning network is the same as the structure of the deep learning network in step 202. The initial deep learning network includes a cascaded coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module.
本实施例中,根据多个训练样本,对深度学习网络进行迭代训练包括,针对每个训练样本,将该训练样本中的全采样图像作为标签,将该训练样本中的样本采样数据作为输入,得到深度学习网络输出的预测图像,将深度学习网络输出的预测图像与全采样图像进行比较,并根据比较结果调整深度学习网络的模型参数;之后,开始下一轮迭代训练;若当前的训练次数满足预设迭代次数,或者本次迭代训练获得的预测图像的精度与训练样本中的全采样样本图像的精度之间的误差小于或等于预设误差阈值时,停止训练,得到训练后深度学习网络。其中,误差采用预设的损失函数计算得到。In this embodiment, the iterative training of the deep learning network based on multiple training samples includes, for each training sample, using a fully sampled image in the training sample as a label, and sample sampling data in the training sample as input. Obtain the predicted image output by the deep learning network, compare the predicted image output by the deep learning network with the fully sampled image, and adjust the model parameters of the deep learning network according to the comparison results; after that, start the next round of iterative training; if the current number of training When the preset number of iterations is met, or the error between the accuracy of the predicted image obtained in this iterative training and the accuracy of the fully sampled sample image in the training sample is less than or equal to the preset error threshold, the training is stopped, and the trained deep learning network is obtained . Among them, the error is calculated by using a preset loss function.
本实施方式中,训练的损失函数可以为最小绝对值偏差损失函数、最小平方误差损失函数等,在此不做具体限定。损失函数用于计算深度学习网络输出的预 测图像与全采样图像之间的误差值。例如,图像分辨率差值、图像清晰度差值或图像相似度差值等。In this embodiment, the training loss function may be a minimum absolute value deviation loss function, a minimum square error loss function, etc., which are not specifically limited here. The loss function is used to calculate the error value between the predicted image output by the deep learning network and the fully sampled image. For example, image resolution difference, image sharpness difference, or image similarity difference, etc.
本实施例中,基于多个训练样本对深度学习网络进行训练,优化了该复数神经网络模型的模型参数,基于这种训练得到的深度学习网络,在输入任意目标对象的非笛卡尔坐标系的欠采样频域数据,就可以得到该目标对象的高分辨率图像,即重建图像,该高分辨率图像就是接近全采样图像的图像,可以满足医学影像中的实际应用需求。In this embodiment, the deep learning network is trained based on multiple training samples, and the model parameters of the complex neural network model are optimized. Based on this training, the deep learning network is input to the non-Cartesian coordinate system of any target object. By under-sampling the frequency domain data, a high-resolution image of the target object, that is, a reconstructed image, can be obtained. The high-resolution image is an image close to a fully-sampled image, which can meet the actual application requirements in medical imaging.
在另一种实施方式中,可以基于端到端的训练机制对深度学习网络进行训练。请一并参阅图7,图7主要针对上述步骤S502中对深度学习网络进行迭代训练进行示例性描述。In another embodiment, the deep learning network can be trained based on an end-to-end training mechanism. Please also refer to FIG. 7. FIG. 7 mainly describes the iterative training of the deep learning network in step S502 as an example.
根据多个所述训练样本,对初始深度学习网络进行迭代训练,并在满足预设条件时,停止训练得到训练后的深度学习网络包括:According to a plurality of the training samples, the initial deep learning network is iteratively trained, and when the preset conditions are met, the training is stopped to obtain the trained deep learning network including:
S701、初始化初始深度学习网络的模型参数。S701: Initialize model parameters of the initial deep learning network.
模型参数的初始化值为预设值。The initial values of the model parameters are preset values.
S702、通过坐标转换卷积模块对训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据。S702: Perform a convolution operation on the sample sample data in the training sample by the coordinate conversion convolution module to obtain the under-sampled non-uniform sample data in the Cartesian coordinate system.
根据多个成像目标获得多个训练样本,采用多个训练样本依次进行端到端的训练。Obtain multiple training samples according to multiple imaging targets, and use multiple training samples to perform end-to-end training in sequence.
在本实施例中,将训练样本的样本采样数据输入到初始深度学习网络中坐标转换卷积模块,基于初始深度学习网络当前的模型参数向前传播。具体地坐标转换卷积模块中级联的第一复数卷积块依次进行复数卷积运算,直至多个第一复数卷积块均完成复数卷积运算,生成笛卡尔坐标系下的欠采样频域数据。In this embodiment, the sample sampling data of the training samples are input to the coordinate conversion convolution module in the initial deep learning network, and forward propagation based on the current model parameters of the initial deep learning network. Specifically, the first complex convolution block cascaded in the coordinate conversion convolution module sequentially performs complex convolution operations, until multiple first complex convolution blocks have completed the complex convolution operation, and the under-sampling frequency in the Cartesian coordinate system is generated. Domain data.
S703、通过密度补偿卷积模块对笛卡尔坐标系下的欠采样非均匀样本数据进行密度补偿,生成对应的欠采样均匀样本数据。S703: Perform density compensation on the under-sampled non-uniform sample data in the Cartesian coordinate system through the density compensation convolution module, and generate corresponding under-sampled uniform sample data.
本步骤与步骤S2022处理相同,在此不再赘述。This step is the same as the processing of step S2022, and will not be repeated here.
S704、通过图像重建卷积模块对欠采样均匀样本数据进行卷积运算,生成欠采样均匀样本数据对应的预测图像。S704: Perform a convolution operation on the under-sampled uniform sample data through the image reconstruction convolution module to generate a predicted image corresponding to the under-sampled uniform sample data.
本步骤与步骤S2023处理相同,在此不再赘述。This step is the same as the processing of step S2023, and will not be repeated here.
S705、若当前不满足预设条件,则更新当前深度学习网络的模型参数,并返回执行通过坐标转换卷积模块对训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据的步骤;若满足预设条件,保存当前的模型参数,获得深度学习网络。S705. If the preset conditions are not currently met, update the model parameters of the current deep learning network, and return to perform the convolution operation on the sample sample data in the training sample through the coordinate conversion convolution module to obtain the undersampling in the Cartesian coordinate system The step of non-uniform sample data; if the preset conditions are met, the current model parameters are saved to obtain a deep learning network.
在执行完S704之后,判定当前是否满足预设条件。该预设条件可以为:当前的训练次数达到预设迭代次数,或者本次迭代训练获得的预测图像的精度与训练样本中的全采样样本图像的精度之间的误差小于或等于预设误差阈值。After S704 is executed, it is determined whether the preset condition is currently met. The preset condition may be: the current number of training reaches the preset number of iterations, or the error between the accuracy of the predicted image obtained in this iteration training and the accuracy of the fully sampled sample image in the training sample is less than or equal to the preset error threshold .
若当前不满足预设条件,则更新当前深度学习网络的模型参数,并返回S702,并继续执行S702~S704。If the preset conditions are not currently met, update the model parameters of the current deep learning network, and return to S702, and continue to execute S702 to S704.
示例性的,假设本次迭代训练获得的预测图像的精度与训练样本中的全采样样本图像的精度之间的误差大于预设误差阈值,则基于该误差,在深度学习网络进行反向传播,对当前深度学习网络的模型参数进行更新。然后返回执行S702~S704,执行下一次迭代,即将训练样本的样本采样数据作为输入,基于更新模型参数的深度学习网络向前传播,并将当前深度学习网络的输出(预测图像)再次与当前训练样本中的全采样样本图像进行对比,直至两者之间的误差小于预设阈值,保存当前的模型参数,获得深度学习网络。其中反向传播是根据前向传播的结果与误差,调整模型参数的过程。Exemplarily, assuming that the error between the accuracy of the predicted image obtained in this iterative training and the accuracy of the fully sampled sample image in the training sample is greater than the preset error threshold, then based on the error, backpropagation is performed in the deep learning network. Update the model parameters of the current deep learning network. Then return to execute S702~S704, execute the next iteration, that is, take the sample sampling data of the training sample as the input, and propagate the deep learning network based on the updated model parameters forward, and the output of the current deep learning network (predicted image) is again with the current training The fully sampled sample images in the sample are compared until the error between the two is less than the preset threshold, the current model parameters are saved, and the deep learning network is obtained. Among them, back propagation is the process of adjusting model parameters based on the results and errors of forward propagation.
若满足预设条件,则保存当前的模型参数,获得深度学习网络。If the preset conditions are met, the current model parameters are saved, and the deep learning network is obtained.
本实施例提供的深度学习网络迭代训练方法,采用端到端的训练方式,直接将采集获得样本采样数据输入深度学习网络,即可得到一个预测图像,将该预测图像与训练样本中的全采样样本图像进行比较会得到一个误差,对该误差进行反向传播,更新深度学习网络的模型参数,直至深度学习网络的输出与全采样样本图像的精度误差小于预设阈值。该方法节约了每一个独立学习任务执行之前所需的数据标注工作,可以直接基于图形处理器GPU进行训练计算,提高了训练效率。The iterative training method of the deep learning network provided in this embodiment adopts an end-to-end training method, and directly inputs the sample data obtained by the collection into the deep learning network to obtain a predicted image. The predicted image is combined with the fully sampled samples in the training sample. The image comparison will get an error, the error is back propagated, and the model parameters of the deep learning network are updated until the accuracy error between the output of the deep learning network and the fully sampled sample image is less than the preset threshold. This method saves the data labeling work required before the execution of each independent learning task, and can directly perform training calculations based on the graphics processor GPU, which improves the training efficiency.
应理解,上述实施例中各步骤的序号的大小并不意味着执行顺序的先后,各过程的执行顺序应以其功能和内在逻辑确定,而不应对本申请实施例的实施过程构成任何限定。It should be understood that the size of the sequence number of each step in the foregoing embodiment does not mean the order of execution. The execution sequence of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiment of the present application.
基于上述实施例所提供的图像重建的方法,本发明实施例进一步给出实现上述方法实施例的装置实施例。Based on the image reconstruction method provided in the foregoing embodiment, the embodiment of the present invention further provides an embodiment of an apparatus for implementing the foregoing method embodiment.
图8为本申请一实施例提供的图像重建装置的组成示意图。如图8所示,图像重建装置80包括:采样模块801和重建模块802。FIG. 8 is a schematic diagram of the composition of an image reconstruction device provided by an embodiment of the application. As shown in FIG. 8, the image reconstruction device 80 includes: a sampling module 801 and a reconstruction module 802.
采样模块801,用于获取目标对象的采样数据;其中,采样数据为基于预设采样模式获取的非笛卡尔坐标系下的欠采样频域数据;The sampling module 801 is configured to obtain sampling data of a target object; wherein the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system obtained based on a preset sampling mode;
重建模块802,用于将采样数据输入训练后的深度学习网络进行处理,获得采样数据对应的重建图像;其中,深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及成像目标的全采样样本图像,对初始深度学习网络训练得到。The reconstruction module 802 is used to input the sampled data into the trained deep learning network for processing, and obtain the reconstructed image corresponding to the sampled data; wherein, the deep learning network is based on the under-sampled sample frequency in the non-Cartesian coordinate system of multiple imaging targets The domain data and the fully sampled sample image of the imaging target are obtained by training the initial deep learning network.
重建模块802,具体用于:The reconstruction module 802 is specifically used for:
将采样数据输入训练后的深度学习网络进行坐标转换,得到采样数据对应的笛卡尔坐标系下的欠采样非均匀频域数据;Input the sampled data into the trained deep learning network for coordinate conversion to obtain the under-sampled non-uniform frequency domain data in the Cartesian coordinate system corresponding to the sampled data;
对笛卡尔坐标系下的欠采样非均匀频域数据进行密度补偿处理,得到笛卡尔坐标系下的欠采样均匀频域数据;Perform density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system;
对欠采样均匀频域数据进行重建处理,得到欠采样均匀频域数据对应的重建图像。Perform reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
重建模块802,还具体用于:The reconstruction module 802 is also specifically used for:
对欠采样均匀频域数据进行填充处理,得到全采样的均匀频域数据;Fill in the under-sampled uniform frequency domain data to obtain fully-sampled uniform frequency domain data;
对均匀频域数据进行傅里叶逆变换,得到欠采样均匀频域数据对应的重建图像。Perform inverse Fourier transform on the uniform frequency domain data to obtain the reconstructed image corresponding to the under-sampled uniform frequency domain data.
本实施例提供的图像重建装置,通过训练后的深度学习网络,对目标对象的采样数据进行处理,从而得到采样数据对应的重建图像,实现了目标对象采样数据的图像重建;其中,采样数据为非笛卡尔坐标系下的欠采样频域数据,深度学习网络为基于多个成像目标的欠采样样本频域数据以及该成像目标的全采样样本图像,对初始深度学习网络训练得到的。相比于现有技术中基于非均匀快速傅里叶变换对非笛卡尔坐标系下的欠采样频域数据进行图像重建的技术方案,本申请实施例中深度学习网络经过预先训练,可以直接根据输入的采样数据 ,获得对应的重建图形,不需要人工选择/调整尺度因子等参数,提高了非笛卡尔坐标系下的欠采样频域数据的重建速度;另一方面,本申请中深度学习网络可以直接基于图形处理器GPU进行加速计算,在保障图像重建精度的前提下,进一步地缩短了非笛卡尔坐标系下的欠采样频域数据的图像重建时间The image reconstruction device provided in this embodiment processes the sampled data of the target object through the trained deep learning network, thereby obtaining the reconstructed image corresponding to the sampled data, and realizes the image reconstruction of the sampled data of the target object; where the sampled data is For the under-sampled frequency domain data in a non-Cartesian coordinate system, the deep learning network is obtained by training the initial deep learning network based on the under-sampled sample frequency domain data of multiple imaging targets and the fully sampled sample image of the imaging target. Compared with the prior art technical solution for image reconstruction based on non-uniform fast Fourier transform for under-sampled frequency domain data in a non-Cartesian coordinate system, the deep learning network in the embodiment of the application is pre-trained and can be directly based on The input sampling data obtains the corresponding reconstruction graph without manual selection/adjustment of parameters such as scale factors, which improves the reconstruction speed of the under-sampled frequency domain data in the non-Cartesian coordinate system; on the other hand, the deep learning network in this application Accelerated calculations can be directly based on the graphics processor GPU. Under the premise of ensuring the accuracy of image reconstruction, the image reconstruction time of under-sampling frequency domain data in non-Cartesian coordinates is further shortened.
图9为本申请另一实施例提供的图像重建装置的组成示意图。如图9所示,图像重建装置80还包括训练模块803。FIG. 9 is a schematic diagram of the composition of an image reconstruction device provided by another embodiment of the application. As shown in FIG. 9, the image reconstruction device 80 further includes a training module 803.
训练模块803,用于: Training module 803, used for:
获取多个训练样本,每个训练样本包括成像目标的全采样样本图像和基于预设采样模式对成像目标进行处理获得的样本采样数据;全采样样本图像用于与初始深度学习网络输出的预测图像进行比较;预设采样模式中相邻的两个采样点之间的间隔不均匀;Acquire multiple training samples, each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on a preset sampling mode; the fully sampled sample image is used to predict the image output by the initial deep learning network Compare; the interval between two adjacent sampling points in the preset sampling mode is not uniform;
根据多个训练样本,对初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络。According to multiple training samples, the initial deep learning network is iteratively trained, and the training is stopped when the preset conditions are met, and the trained deep learning network is obtained.
可选地,训练模块803,具体用于:Optionally, the training module 803 is specifically used for:
获取每个成像目标对应的全采样样本图像,全采样样本图像由医学影像设备采集;Obtain the full sample sample image corresponding to each imaging target, and the full sample sample image is collected by the medical imaging equipment;
基于预设采样模式获取每个成像目标的样本采样数据,样本采样数据为非笛卡尔坐标系下的欠采样频域数据;Obtain sample sampling data of each imaging target based on the preset sampling mode, the sample sampling data is the under-sampling frequency domain data in a non-Cartesian coordinate system;
将每个成像目标对应的全采样样本图像和样本采样数据作为一个训练样本。The fully sampled sample image and sample sample data corresponding to each imaging target are used as a training sample.
可选地,深度学习网络包括:依次级联的坐标转换卷积模块、傅里叶逆变换模块以及第二复数卷积层;训练模块803,还具体用于:Optionally, the deep learning network includes: a coordinate transformation convolution module, an inverse Fourier transformation module, and a second complex convolution layer that are sequentially cascaded; the training module 803 is also specifically used for:
初始化初始深度学习网络的模型参数;Initialize the model parameters of the initial deep learning network;
通过坐标转换卷积模块对训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据;Use the coordinate conversion convolution module to perform convolution operation on the sample sample data in the training sample to obtain the under-sampled non-uniform sample data in the Cartesian coordinate system;
通过密度补偿卷积模块对笛卡尔坐标系下的欠采样非均匀样本数据进行密度补偿,生成对应的欠采样均匀样本数据;Perform density compensation on the under-sampled non-uniform sample data in the Cartesian coordinate system through the density compensation convolution module to generate corresponding under-sampled uniform sample data;
通过图像重建卷积模块对欠采样均匀样本数据进行卷积运算,生成欠采样均匀样本数据对应的预测图像;Perform convolution operation on the under-sampled uniform sample data through the image reconstruction convolution module to generate the predicted image corresponding to the under-sampled uniform sample data;
若当前不满足预设条件,则更新当前深度学习网络的模型参数,并返回执行通过坐标转换卷积模块对训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据的步骤;若满足预设条件,保存当前的模型参数,获得深度学习网络。If the preset conditions are not currently met, update the model parameters of the current deep learning network, and return to perform the convolution operation of the sample sampling data in the training sample through the coordinate conversion convolution module to obtain the under-sampling non-uniformity in the Cartesian coordinate system The step of sample data; if the preset conditions are met, the current model parameters are saved to obtain the deep learning network.
可选地,坐标转换卷积模块包括多个级联的第一复数卷积模块,第二复数卷积层包括多个级联的第二复数卷积模块;第一复数卷积模块和第二复数卷积模块的卷积核大小相同。Optionally, the coordinate transformation convolution module includes a plurality of cascaded first complex convolution modules, and the second complex convolution layer includes a plurality of cascaded second complex convolution modules; the first complex convolution module and the second complex convolution module; The size of the convolution kernel of the complex convolution module is the same.
可选地,预设采样模式包括径向采样或螺旋扫描采样。Optionally, the preset sampling mode includes radial sampling or spiral scanning sampling.
本实施例提供的图像重建装置,基于多个训练样本对初始深度学习网络进行训练,优化了该初始深度学习网络的模型参数,基于这种训练得到的深度学习网络,在输入任意目标对象的非笛卡尔坐标系下的欠采样频域数据,就可以得到该目标对象的高分辨率图像,即重建图像,该高分辨率图像就是接近全采样图像的图像,可以满足医学影像中的实际应用需求。The image reconstruction device provided in this embodiment trains the initial deep learning network based on multiple training samples, and optimizes the model parameters of the initial deep learning network. Based on this training, the deep learning network is used to input any target object. The under-sampling frequency domain data in the Cartesian coordinate system can obtain a high-resolution image of the target object, that is, a reconstructed image. The high-resolution image is an image close to the full-sampled image, which can meet the actual application requirements in medical imaging. .
图8和图9所示实施例提供的图像重建装置,可用于执行上述方法实施例中的技术方案,其实现原理和技术效果类似,本实施例此处不再赘述。The image reconstruction apparatus provided by the embodiments shown in FIG. 8 and FIG. 9 can be used to implement the technical solutions in the foregoing method embodiments, and their implementation principles and technical effects are similar, and will not be repeated here in this embodiment.
图10是本申请一实施例提供的图像重建设备的示意图。如图9所示,该实施例的图像重建终端设备100包括:至少一个处理器1001、存储器1002以及存储在存储器1002中并可在处理器1001上运行的计算机可读指令。图像重建设备还包括通信部件1003,其中,处理器1001、存储器1002以及通信部件1003通过总线1004连接。Fig. 10 is a schematic diagram of an image reconstruction device provided by an embodiment of the present application. As shown in FIG. 9, the image reconstruction terminal device 100 of this embodiment includes: at least one processor 1001, a memory 1002, and computer-readable instructions stored in the memory 1002 and executable on the processor 1001. The image reconstruction device further includes a communication component 1003, wherein the processor 1001, the memory 1002, and the communication component 1003 are connected by a bus 1004.
处理器1001执行计算机可读指令时实现上述各个图像重建方法实施例中的步骤,例如图2所示实施例中的步骤S201至步骤S202。或者,处理器1001执行所述计算机可读指令时实现上述各装置实施例中各模块/单元的功能,例如图8所示模块801至802的功能。The processor 1001 implements the steps in the foregoing image reconstruction method embodiments when executing computer-readable instructions, such as step S201 to step S202 in the embodiment shown in FIG. 2. Alternatively, when the processor 1001 executes the computer-readable instructions, the functions of the modules/units in the foregoing device embodiments, for example, the functions of the modules 801 to 802 shown in FIG. 8 are realized.
示例性的,计算机可读指令可以被分割成一个或多个模块/单元,一个或者多个模块/单元被存储在存储器1002中,并由处理器1001执行,以完成本申请。所述一个或多个模块/单元可以是能够完成特定功能的一系列计算机可读指令段,该指令段用于描述计算机可读指令在图像重建设备100中的执行过程。Exemplarily, the computer-readable instructions may be divided into one or more modules/units, and the one or more modules/units are stored in the memory 1002 and executed by the processor 1001 to complete the present application. The one or more modules/units may be a series of computer-readable instruction segments capable of completing specific functions, and the instruction segments are used to describe the execution process of the computer-readable instructions in the image reconstruction device 100.
本领域技术人员可以理解,图10仅仅是图像重建装置设备的示例,并不构成对图像重建设备的限定,可以包括比图示更多或更少的部件,或者组合某些部件,或者不同的部件,例如输入输出设备、网络接入设备、总线等。Those skilled in the art can understand that FIG. 10 is only an example of the image reconstruction device and does not constitute a limitation on the image reconstruction device. It may include more or less components than shown in the figure, or a combination of certain components, or different components. Components, such as input and output devices, network access devices, buses, etc.
处理器1001可以是中央处理单元(Central Processing Unit,CPU),还可以是其他通用处理器、数字信号处理器(Digital Signal Processor,DSP)、专用集成电路(Application Specific Integrated Circuit,ASIC)、现成可编程门阵列(Field-Programmable Gate Array,FPGA)或者其他可编程逻辑器件、分立门或者晶体管逻辑器件、分立硬件组件等。通用处理器可以是微处理器或者该处理器也可以是任何常规的处理器等。The processor 1001 can be a central processing unit (Central Processing Unit, CPU), other general-purpose processors, digital signal processors (Digital Signal Processor, DSP), application specific integrated circuits (Application Specific Integrated Circuit, ASIC), ready-made Field-Programmable Gate Array (FPGA) or other programmable logic devices, discrete gates or transistor logic devices, discrete hardware components, etc. The general-purpose processor may be a microprocessor or the processor may also be any conventional processor or the like.
存储器1002可以是图像重建设备的内部存储单元,也可以是图像重建设备的外部存储设备,例如插接式硬盘,智能存储卡(Smart Media Card,SMC),安全数字(Secure Digital,SD)卡,闪存卡(Flash Card)等。所述存储器1002用于存储所述计算机可读指令以及图像重建设备所需的其他程序和数据。所述存储器1002还可以用于暂时地存储已经输出或者将要输出的数据。The memory 1002 may be an internal storage unit of the image reconstruction device, or an external storage device of the image reconstruction device, such as a plug-in hard disk, a smart media card (SMC), or a secure digital (SD) card. Flash Card, etc. The memory 1002 is used to store the computer readable instructions and other programs and data required by the image reconstruction device. The memory 1002 can also be used to temporarily store data that has been output or will be output.
总线可以是工业标准体系结构(Industry Standard Architecture,ISA)总线、外部设备互连(Peripheral Component,PCI)总线或扩展工业标准体系结构(Extended Industry Standard Architecture,EISA)总线等。总线可以分为地址总线、数据总线、控制总线等。为便于表示,本申请附图中的总线并不限定仅有一根总线或一种类型的总线。The bus can be an Industry Standard Architecture (ISA) bus, Peripheral Component (PCI) bus, or Extended Industry Standard Architecture (EISA) bus, etc. The bus can be divided into address bus, data bus, control bus and so on. For ease of representation, the buses in the drawings of this application are not limited to only one bus or one type of bus.
本申请实施例还提供了一种计算机可读存储介质,计算机可读存储介质存储有计算机可读指令,计算机可读指令被处理器执行时实现可实现上述各个方法实施例中的步骤。The embodiments of the present application also provide a computer-readable storage medium, and the computer-readable storage medium stores computer-readable instructions. When the computer-readable instructions are executed by a processor, the steps in the foregoing method embodiments can be realized.
本申请实施例提供了一种计算机程序产品,当计算机程序产品在图像重建设备上运行时,使得图像重建设备执行时可实现上述各个方法实施例中的步骤。The embodiments of the present application provide a computer program product. When the computer program product runs on an image reconstruction device, the image reconstruction device can implement the steps in the foregoing method embodiments when executed.
所述集成的单元如果以软件功能单元的形式实现并作为独立的产品销售或使用时,可以存储在一个计算机可读取存储介质中。基于这样的理解,本申请实现上述实施例方法中的全部或部分流程,可以通过计算机可读指令来指令相关的 硬件来完成,所述的计算机可读指令可存储于一计算机可读存储介质中,该计算机可读指令在被处理器执行时,可实现上述各个方法实施例的步骤。其中,所述计算机可读指令包括计算机可读指令代码,所述计算机可读指令代码可以为源代码形式、对象代码形式、可执行文件或某些中间形式等。所述计算机可读介质至少可以包括:能够将计算机可读指令代码携带到图像重建设备的任何实体或装置、记录介质、计算机存储器、只读存储器(ROM,Read-Only Memory)、随机存取存储器(RAM,Random Access Memory)、电载波信号、电信信号以及软件分发介质。例如U盘、移动硬盘、磁碟或者光盘等。在某些司法管辖区,根据立法和专利实践,计算机可读介质不可以是电载波信号和电信信号。If the integrated unit is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer readable storage medium. Based on this understanding, the implementation of all or part of the processes in the above-mentioned embodiments and methods in this application can be accomplished by instructing relevant hardware through computer-readable instructions, and the computer-readable instructions can be stored in a computer-readable storage medium. When the computer-readable instructions are executed by the processor, they can implement the steps of the foregoing method embodiments. Wherein, the computer-readable instruction includes computer-readable instruction code, and the computer-readable instruction code may be in the form of source code, object code, executable file, or some intermediate form. The computer-readable medium may at least include: any entity or device capable of carrying computer-readable instruction codes to the image reconstruction equipment, recording medium, computer memory, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), electric carrier signal, telecommunications signal and software distribution medium. For example, U disk, mobile hard disk, floppy disk or CD-ROM, etc. In some jurisdictions, according to legislation and patent practices, computer-readable media cannot be electrical carrier signals and telecommunication signals.
在上述实施例中,对各个实施例的描述都各有侧重,某个实施例中没有详述或记载的部分,可以参见其它实施例的相关描述。In the above-mentioned embodiments, the description of each embodiment has its own emphasis. For parts that are not described in detail or recorded in an embodiment, reference may be made to related descriptions of other embodiments.
本领域普通技术人员可以意识到,结合本文中所公开的实施例描述的各示例的单元及算法步骤,能够以电子硬件、或者计算机软件和电子硬件的结合来实现。这些功能究竟以硬件还是软件方式来执行,取决于技术方案的特定应用和设计约束条件。专业技术人员可以对每个特定的应用来使用不同方法来实现所描述的功能,但是这种实现不应认为超出本申请的范围。A person of ordinary skill in the art may realize that the units and algorithm steps of the examples described in combination with the embodiments disclosed herein can be implemented by electronic hardware or a combination of computer software and electronic hardware. Whether these functions are performed by hardware or software depends on the specific application and design constraint conditions of the technical solution. Professionals and technicians can use different methods for each specific application to implement the described functions, but such implementation should not be considered beyond the scope of this application.
在本申请所提供的实施例中,应该理解到,所揭露的装置/网络设备和方法,可以通过其它的方式实现。例如,以上所描述的装置/网络设备实施例仅仅是示意性的,例如,所述模块或单元的划分,仅仅为一种逻辑功能划分,实际实现时可以有另外的划分方式,例如多个单元或组件可以结合或者可以集成到另一个系统,或一些特征可以忽略,或不执行。另一点,所显示或讨论的相互之间的耦合或直接耦合或通讯连接可以是通过一些接口,装置或单元的间接耦合或通讯连接,可以是电性,机械或其它的形式。In the embodiments provided in this application, it should be understood that the disclosed apparatus/network equipment and method may be implemented in other ways. For example, the device/network device embodiments described above are only illustrative. For example, the division of the modules or units is only a logical function division, and there may be other divisions in actual implementation, such as multiple units. Or components can be combined or integrated into another system, or some features can be omitted or not implemented. In addition, the displayed or discussed mutual coupling or direct coupling or communication connection may be indirect coupling or communication connection through some interfaces, devices or units, and may be in electrical, mechanical or other forms.
所述作为分离部件说明的单元可以是或者也可以不是物理上分开的,作为单元显示的部件可以是或者也可以不是物理单元,即可以位于一个地方,或者也可以分布到多个网络单元上。可以根据实际的需要选择其中的部分或者全部单元来实现本实施例方案的目的。The units described as separate components may or may not be physically separated, and the components displayed as units may or may not be physical units, that is, they may be located in one place, or they may be distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the objectives of the solutions of the embodiments.
以上所述实施例仅用以说明本申请的技术方案,而非对其限制;尽管参照前述实施例对本申请进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本申请各实施例技术方案的精神和范围,均应包含在本申请的保护范围之内。The above-mentioned embodiments are only used to illustrate the technical solutions of the present application, not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, a person of ordinary skill in the art should understand that it can still implement the foregoing The technical solutions recorded in the examples are modified, or some of the technical features are equivalently replaced; these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the application, and should be included in Within the scope of protection of this application.

Claims (20)

  1. 一种图像重建方法,其特征在于,包括:An image reconstruction method, characterized in that it comprises:
    获取目标对象的采样数据;其中,所述采样数据为基于预设采样模式获取的非笛卡尔坐标系下的欠采样频域数据;Acquiring sampling data of the target object; wherein the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system acquired based on a preset sampling mode;
    将所述采样数据输入训练后的深度学习网络进行处理,获得所述采样数据对应的重建图像;其中,所述深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及所述成像目标的全采样样本图像,对初始深度学习网络训练得到。Input the sampled data into the trained deep learning network for processing, and obtain the reconstructed image corresponding to the sampled data; wherein, the deep learning network is based on the under-sampled sample frequency in the non-Cartesian coordinate system of multiple imaging targets. The domain data and the fully sampled sample image of the imaging target are obtained by training the initial deep learning network.
  2. 如权利要求1所述的图像重建方法,其特征在于,所述将所述采样数据输入训练后的深度学习网络进行处理,获得所述采样数据对应的重建图像,包括:8. The image reconstruction method according to claim 1, wherein said inputting said sampled data into a trained deep learning network for processing to obtain a reconstructed image corresponding to said sampled data comprises:
    将所述采样数据输入训练后的深度学习网络进行坐标转换,得到所述采样数据对应的笛卡尔坐标系下的欠采样非均匀频域数据;Input the sampled data into the trained deep learning network to perform coordinate conversion to obtain the under-sampled non-uniform frequency domain data in the Cartesian coordinate system corresponding to the sampled data;
    对所述笛卡尔坐标系下的欠采样非均匀频域数据进行密度补偿处理,得到笛卡尔坐标系下的欠采样均匀频域数据;Performing density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system;
    对所述欠采样均匀频域数据进行重建处理,得到所述欠采样均匀频域数据对应的重建图像。Perform reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
  3. 如权利要求2所述的图像重建方法,其特征在于,所述对所述欠采样均匀频域数据进行重建处理,得到所述欠采样均匀频域数据对应的重建图像,包括:3. The image reconstruction method according to claim 2, wherein the performing reconstruction processing on the under-sampled uniform frequency domain data to obtain the reconstructed image corresponding to the under-sampled uniform frequency domain data comprises:
    对所述欠采样均匀频域数据进行填充处理,得到全采样的均匀频域数据;Performing filling processing on the under-sampled uniform frequency domain data to obtain fully-sampled uniform frequency domain data;
    对所述均匀频域数据进行傅里叶逆变换,得到欠采样均匀频域数据对应的重建图像。Perform inverse Fourier transform on the uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
  4. 如权利要求1-3任一项所述的图像重建方法,其特征在于,所述将所述采样数据输入训练后的深度学习网络进行图像重建之前,所述方法还包括:The image reconstruction method according to any one of claims 1 to 3, wherein before the input of the sampled data into the trained deep learning network for image reconstruction, the method further comprises:
    获取多个训练样本,每个训练样本包括成像目标的全采样样本图 像和基于所述预设采样模式对所述成像目标进行处理获得的样本采样数据;所述全采样样本图像用于与所述初始深度学习网络输出的预测图像进行比较;所述预设采样模式中相邻的两个采样点之间的间隔不均匀;Acquire a plurality of training samples, each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on the preset sampling mode; the fully sampled sample image is used to communicate with the The predicted images output by the initial deep learning network are compared; the interval between two adjacent sampling points in the preset sampling mode is not uniform;
    根据多个所述训练样本,对所述初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络。According to a plurality of the training samples, iterative training is performed on the initial deep learning network, and the training is stopped when a preset condition is met, to obtain a trained deep learning network.
  5. 如权利要求4所述的图像重建方法,其特征在于,用于训练的成像目标有多个;The image reconstruction method according to claim 4, wherein there are multiple imaging targets used for training;
    所述获取多个训练样本包括:The obtaining multiple training samples includes:
    获取每个成像目标对应的全采样样本图像,所述全采样样本图像由医学影像设备采集;Acquiring a fully sampled sample image corresponding to each imaging target, the fully sampled sample image being collected by a medical imaging device;
    基于所述预设采样模式获取每个所述成像目标的样本采样数据,所述样本采样数据为非笛卡尔坐标系下的欠采样频域数据;Acquiring sample sampling data of each imaging target based on the preset sampling mode, where the sample sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system;
    将每个所述成像目标对应的全采样样本图像和样本采样数据作为一个训练样本。The fully sampled sample image and sample sample data corresponding to each imaging target are used as a training sample.
  6. 如权利要求4所述的图像重建方法,其特征在于,所述初始深度学习网络包括:依次级联的坐标转换卷积模块、密度补偿卷积模块以及图像重建卷积模块;5. The image reconstruction method according to claim 4, wherein the initial deep learning network comprises: a coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module that are sequentially cascaded;
    所述根据多个所述训练样本,对所述初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络包括:The iterative training of the initial deep learning network based on a plurality of the training samples, and stopping the training when a preset condition is met, obtaining the trained deep learning network includes:
    初始化所述初始深度学习网络的模型参数;Initialize the model parameters of the initial deep learning network;
    通过所述坐标转换卷积模块对所述训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据;Performing a convolution operation on the sample sample data in the training sample by the coordinate conversion convolution module to obtain under-sampled non-uniform sample data in a Cartesian coordinate system;
    通过所述密度补偿卷积模块对所述笛卡尔坐标系下的欠采样非均匀样本数据进行密度补偿,生成对应的欠采样均匀样本数据;Performing density compensation on the under-sampled non-uniform sample data in the Cartesian coordinate system by the density compensation convolution module, and generate corresponding under-sampled uniform sample data;
    通过所述图像重建卷积模块对所述欠采样均匀样本数据进行卷积运算,生成所述欠采样均匀样本数据对应的预测图像;Performing a convolution operation on the under-sampled uniform sample data by the image reconstruction convolution module to generate a predicted image corresponding to the under-sampled uniform sample data;
    若当前不满足预设条件,则更新当前深度学习网络的模型参数,并返回执行所述通过所述坐标转换卷积模块对所述训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据的步骤;若满足预设条件,保存当前的模型参数,获得所述深度学习网络。If the preset conditions are not currently met, update the model parameters of the current deep learning network, and return to perform the convolution operation of the sample sample data in the training sample through the coordinate conversion convolution module to obtain the Cartesian coordinate system The step of under-sampling non-uniform sample data; if the preset conditions are met, save the current model parameters to obtain the deep learning network.
  7. 如权利要求1所述的图像重建方法,其特征在于,所述预设采样模式包括径向采样或螺旋扫描采样。8. The image reconstruction method according to claim 1, wherein the preset sampling mode includes radial sampling or helical scanning sampling.
  8. 一种图像重建装置,其特征在于,包括:An image reconstruction device, characterized in that it comprises:
    获取模块,用于获取目标对象的采样数据;其中,所述采样数据为基于预设采样模式获取的非笛卡尔坐标系下的欠采样频域数据;An acquisition module for acquiring sampling data of the target object; wherein the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system acquired based on a preset sampling mode;
    重建模块,用于将所述采样数据输入训练后的深度学习网络进行处理,获得所述采样数据对应的重建图像;其中,所述深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及所述成像目标的全采样样本图像,对初始深度学习网络训练得到。The reconstruction module is used to input the sampled data into the trained deep learning network for processing to obtain the reconstructed image corresponding to the sampled data; wherein, the deep learning network is based on multiple imaging targets in a non-Cartesian coordinate system The under-sampled sample frequency domain data of and the fully sampled sample image of the imaging target are obtained by training the initial deep learning network.
  9. 一种图像重建设备,包括存储器、处理器以及存储在所述存储器中并可在所述处理器上运行的计算机可读指令,其特征在于,所述处理器执行所述计算机可读指令时实现如下步骤:An image reconstruction device, comprising a memory, a processor, and computer-readable instructions stored in the memory and running on the processor, wherein the processor executes the computer-readable instructions to implement The following steps:
    获取目标对象的采样数据;其中,所述采样数据为基于预设采样模式获取的非笛卡尔坐标系下的欠采样频域数据;Acquiring sampling data of the target object; wherein the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system acquired based on a preset sampling mode;
    将所述采样数据输入训练后的深度学习网络进行处理,获得所述采样数据对应的重建图像;其中,所述深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及所述成像目标的全采样样本图像,对初始深度学习网络训练得到。Input the sampled data into the trained deep learning network for processing, and obtain the reconstructed image corresponding to the sampled data; wherein, the deep learning network is based on the under-sampled sample frequency in the non-Cartesian coordinate system of multiple imaging targets. The domain data and the fully sampled sample image of the imaging target are obtained by training the initial deep learning network.
  10. 如权利要求9所述的图像重建设备,其特征在于,所述将所述采样数据输入训练后的深度学习网络进行处理,获得所述采样数据对应的重建图像,包括:9. The image reconstruction device according to claim 9, wherein said inputting said sampled data into a trained deep learning network for processing to obtain a reconstructed image corresponding to said sampled data comprises:
    将所述采样数据输入训练后的深度学习网络进行坐标转换,得到所述采样数据对应的笛卡尔坐标系下的欠采样非均匀频域数据;Input the sampled data into the trained deep learning network to perform coordinate conversion to obtain the under-sampled non-uniform frequency domain data in the Cartesian coordinate system corresponding to the sampled data;
    对所述笛卡尔坐标系下的欠采样非均匀频域数据进行密度补偿处理,得到笛卡尔坐标系下的欠采样均匀频域数据;Performing density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system;
    对所述欠采样均匀频域数据进行重建处理,得到所述欠采样均匀频域数据对应的重建图像。Perform reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
  11. 如权利要求10所述的图像重建设备,其特征在于,所述对所述欠采样均匀频域数据进行重建处理,得到所述欠采样均匀频域数据对应的重建图像,包括:11. The image reconstruction device according to claim 10, wherein the performing reconstruction processing on the under-sampled uniform frequency domain data to obtain the reconstructed image corresponding to the under-sampled uniform frequency domain data comprises:
    对所述欠采样均匀频域数据进行填充处理,得到全采样的均匀频域数据;Performing filling processing on the under-sampled uniform frequency domain data to obtain fully-sampled uniform frequency domain data;
    对所述均匀频域数据进行傅里叶逆变换,得到欠采样均匀频域数据对应的重建图像。Perform inverse Fourier transform on the uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
  12. 如权利要求9-11任一项所述的图像重建设备,其特征在于,所述将所述采样数据输入训练后的深度学习网络进行图像重建之前,所述处理器执行所述计算机可读指令时还实现如下步骤:The image reconstruction device according to any one of claims 9-11, wherein the processor executes the computer-readable instructions before inputting the sampled data into the trained deep learning network for image reconstruction It also implements the following steps:
    获取多个训练样本,每个训练样本包括成像目标的全采样样本图像和基于所述预设采样模式对所述成像目标进行处理获得的样本采样数据;所述全采样样本图像用于与所述初始深度学习网络输出的预测图像进行比较;所述预设采样模式中相邻的两个采样点之间的间隔不均匀;Acquire a plurality of training samples, each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on the preset sampling mode; the fully sampled sample image is used to communicate with the The predicted images output by the initial deep learning network are compared; the interval between two adjacent sampling points in the preset sampling mode is not uniform;
    根据多个所述训练样本,对所述初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络。According to a plurality of the training samples, iterative training is performed on the initial deep learning network, and the training is stopped when a preset condition is met, to obtain a trained deep learning network.
  13. 如权利要求12所述的图像重建设备,其特征在于,用于训练的成像目标有多个;The image reconstruction device according to claim 12, wherein there are multiple imaging targets used for training;
    所述获取多个训练样本包括:The obtaining multiple training samples includes:
    获取每个成像目标对应的全采样样本图像,所述全采样样本图像由医学影像设备采集;Acquiring a fully sampled sample image corresponding to each imaging target, the fully sampled sample image being collected by a medical imaging device;
    基于所述预设采样模式获取每个所述成像目标的样本采样数据,所述样本采样数据为非笛卡尔坐标系下的欠采样频域数据;Acquiring sample sampling data of each imaging target based on the preset sampling mode, where the sample sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system;
    将每个所述成像目标对应的全采样样本图像和样本采样数据作为一个训练样本。The fully sampled sample image and sample sample data corresponding to each imaging target are used as a training sample.
  14. 如权利要求12所述的图像重建设备,其特征在于,所述初始深度学习网络包括:依次级联的坐标转换卷积模块、密度补偿卷积模块以及图像重建卷积模块;The image reconstruction device according to claim 12, wherein the initial deep learning network comprises: a coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module that are sequentially cascaded;
    所述根据多个所述训练样本,对所述初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络包括:The iterative training of the initial deep learning network based on a plurality of the training samples, and stopping the training when a preset condition is met, obtaining the trained deep learning network includes:
    初始化所述初始深度学习网络的模型参数;Initialize the model parameters of the initial deep learning network;
    通过所述坐标转换卷积模块对所述训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据;Performing a convolution operation on the sample sample data in the training sample by the coordinate conversion convolution module to obtain under-sampled non-uniform sample data in a Cartesian coordinate system;
    通过所述密度补偿卷积模块对所述笛卡尔坐标系下的欠采样非均匀样本数据进行密度补偿,生成对应的欠采样均匀样本数据;Performing density compensation on the under-sampled non-uniform sample data in the Cartesian coordinate system by the density compensation convolution module, and generate corresponding under-sampled uniform sample data;
    通过所述图像重建卷积模块对所述欠采样均匀样本数据进行卷积运算,生成所述欠采样均匀样本数据对应的预测图像;Performing a convolution operation on the under-sampled uniform sample data by the image reconstruction convolution module to generate a predicted image corresponding to the under-sampled uniform sample data;
    若当前不满足预设条件,则更新当前深度学习网络的模型参数,并返回执行所述通过所述坐标转换卷积模块对所述训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据的步骤;若满足预设条件,保存当前的模型参数,获得所述深度学习网络。If the preset conditions are not currently met, update the model parameters of the current deep learning network, and return to perform the convolution operation of the sample sample data in the training sample through the coordinate conversion convolution module to obtain the Cartesian coordinate system The step of under-sampling non-uniform sample data; if the preset conditions are met, save the current model parameters to obtain the deep learning network.
  15. 一种计算机可读存储介质,所述计算机可读存储介质存储有计算机可读指令,其特征在于,所述计算机可读指令被处理器执行时实现如下步骤:A computer-readable storage medium, the computer-readable storage medium storing computer-readable instructions, wherein the computer-readable instructions are executed by a processor to implement the following steps:
    获取目标对象的采样数据;其中,所述采样数据为基于预设采样模式获取的非笛卡尔坐标系下的欠采样频域数据;Acquiring sampling data of the target object; wherein the sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system acquired based on a preset sampling mode;
    将所述采样数据输入训练后的深度学习网络进行处理,获得所述 采样数据对应的重建图像;其中,所述深度学习网络是基于多个成像目标的非笛卡尔坐标系下的欠采样样本频域数据以及所述成像目标的全采样样本图像,对初始深度学习网络训练得到。Input the sampled data into the trained deep learning network for processing, and obtain the reconstructed image corresponding to the sampled data; wherein, the deep learning network is based on the under-sampled sample frequency in the non-Cartesian coordinate system of multiple imaging targets. The domain data and the fully sampled sample image of the imaging target are obtained by training the initial deep learning network.
  16. 如权利要求15所述的计算机可读存储介质,其特征在于,所述将所述采样数据输入训练后的深度学习网络进行处理,获得所述采样数据对应的重建图像,包括:15. The computer-readable storage medium of claim 15, wherein the inputting the sampled data into a trained deep learning network for processing to obtain a reconstructed image corresponding to the sampled data comprises:
    将所述采样数据输入训练后的深度学习网络进行坐标转换,得到所述采样数据对应的笛卡尔坐标系下的欠采样非均匀频域数据;Input the sampled data into the trained deep learning network to perform coordinate conversion to obtain the under-sampled non-uniform frequency domain data in the Cartesian coordinate system corresponding to the sampled data;
    对所述笛卡尔坐标系下的欠采样非均匀频域数据进行密度补偿处理,得到笛卡尔坐标系下的欠采样均匀频域数据;Performing density compensation processing on the under-sampled non-uniform frequency domain data in the Cartesian coordinate system to obtain the under-sampled uniform frequency domain data in the Cartesian coordinate system;
    对所述欠采样均匀频域数据进行重建处理,得到所述欠采样均匀频域数据对应的重建图像。Perform reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
  17. 如权利要求16所述的计算机可读存储介质,其特征在于,所述对所述欠采样均匀频域数据进行重建处理,得到所述欠采样均匀频域数据对应的重建图像,包括:15. The computer-readable storage medium of claim 16, wherein the performing reconstruction processing on the under-sampled uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data comprises:
    对所述欠采样均匀频域数据进行填充处理,得到全采样的均匀频域数据;Performing filling processing on the under-sampled uniform frequency domain data to obtain fully-sampled uniform frequency domain data;
    对所述均匀频域数据进行傅里叶逆变换,得到欠采样均匀频域数据对应的重建图像。Perform inverse Fourier transform on the uniform frequency domain data to obtain a reconstructed image corresponding to the under-sampled uniform frequency domain data.
  18. 如权利要求15-17任一项所述的计算机可读存储介质,其特征在于,所述将所述采样数据输入训练后的深度学习网络进行图像重建之前,所述计算机可读指令被处理器执行时还实现如下步骤:The computer-readable storage medium according to any one of claims 15-17, wherein, before the sampling data is input into the trained deep learning network for image reconstruction, the computer-readable instructions are processed by the processor The following steps are also implemented during execution:
    获取多个训练样本,每个训练样本包括成像目标的全采样样本图像和基于所述预设采样模式对所述成像目标进行处理获得的样本采样数据;所述全采样样本图像用于与所述初始深度学习网络输出的预测图像进行比较;所述预设采样模式中相邻的两个采样点之间的间隔不均匀;Acquire a plurality of training samples, each training sample includes a fully sampled sample image of the imaging target and sample sample data obtained by processing the imaging target based on the preset sampling mode; the fully sampled sample image is used to communicate with the The predicted images output by the initial deep learning network are compared; the interval between two adjacent sampling points in the preset sampling mode is not uniform;
    根据多个所述训练样本,对所述初始深度学习网络进行迭代训练 ,并在满足预设条件时停止训练,得到训练后的深度学习网络。According to a plurality of the training samples, iterative training is performed on the initial deep learning network, and the training is stopped when a preset condition is met, to obtain a trained deep learning network.
  19. 如权利要求18所述的计算机可读存储介质,其特征在于,用于训练的成像目标有多个;18. The computer-readable storage medium of claim 18, wherein there are multiple imaging targets used for training;
    所述获取多个训练样本包括:The obtaining multiple training samples includes:
    获取每个成像目标对应的全采样样本图像,所述全采样样本图像由医学影像设备采集;Acquiring a fully sampled sample image corresponding to each imaging target, the fully sampled sample image being collected by a medical imaging device;
    基于所述预设采样模式获取每个所述成像目标的样本采样数据,所述样本采样数据为非笛卡尔坐标系下的欠采样频域数据;Acquiring sample sampling data of each imaging target based on the preset sampling mode, where the sample sampling data is under-sampling frequency domain data in a non-Cartesian coordinate system;
    将每个所述成像目标对应的全采样样本图像和样本采样数据作为一个训练样本。The fully sampled sample image and sample sample data corresponding to each imaging target are used as a training sample.
  20. 如权利要求18所述的计算机可读存储介质,其特征在于,所述初始深度学习网络包括:依次级联的坐标转换卷积模块、密度补偿卷积模块以及图像重建卷积模块;18. The computer-readable storage medium of claim 18, wherein the initial deep learning network comprises: a coordinate conversion convolution module, a density compensation convolution module, and an image reconstruction convolution module that are sequentially cascaded;
    所述根据多个所述训练样本,对所述初始深度学习网络进行迭代训练,并在满足预设条件时停止训练,得到训练后的深度学习网络包括:The iterative training of the initial deep learning network based on a plurality of the training samples, and stopping the training when a preset condition is met, obtaining the trained deep learning network includes:
    初始化所述初始深度学习网络的模型参数;Initialize the model parameters of the initial deep learning network;
    通过所述坐标转换卷积模块对所述训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据;Performing a convolution operation on the sample sample data in the training sample by the coordinate conversion convolution module to obtain under-sampled non-uniform sample data in a Cartesian coordinate system;
    通过所述密度补偿卷积模块对所述笛卡尔坐标系下的欠采样非均匀样本数据进行密度补偿,生成对应的欠采样均匀样本数据;Performing density compensation on the under-sampled non-uniform sample data in the Cartesian coordinate system by the density compensation convolution module, and generate corresponding under-sampled uniform sample data;
    通过所述图像重建卷积模块对所述欠采样均匀样本数据进行卷积运算,生成所述欠采样均匀样本数据对应的预测图像;Performing a convolution operation on the under-sampled uniform sample data by the image reconstruction convolution module to generate a predicted image corresponding to the under-sampled uniform sample data;
    若当前不满足预设条件,则更新当前深度学习网络的模型参数,并返回执行所述通过所述坐标转换卷积模块对所述训练样本中的样本采样数据进行卷积运算得到笛卡尔坐标系下的欠采样非均匀样本数据的步骤;若满足预设条件,保存当前的模型参数,获得所述深度学习网络。If the preset conditions are not currently met, update the model parameters of the current deep learning network, and return to perform the convolution operation of the sample sample data in the training sample through the coordinate conversion convolution module to obtain the Cartesian coordinate system The step of under-sampling non-uniform sample data; if the preset conditions are met, save the current model parameters to obtain the deep learning network.
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