WO2021042712A1

WO2021042712A1 - Pet detection apparatus

Info

Publication number: WO2021042712A1
Application number: PCT/CN2020/082534
Authority: WO
Inventors: 张弛
Original assignee: 上海鹏钼医疗科技有限公司
Priority date: 2019-08-27
Filing date: 2020-03-31
Publication date: 2021-03-11

Abstract

Disclosed is a PET detection apparatus, comprising a base (1); a detection assembly (2) connected to the base (1), wherein the detection assembly (2) is configured to be at least capable of rotating and being positioned relative to the base (1) and longitudinally moving and being positioned relative to the base (1), the detection assembly (2) comprises a first detection plate (21) and a second detection plate (22), which are arranged opposite each other and in parallel, either one of the first detection plate (21) and the second detection plate (22) comprises a detection layer (3), a signal reading layer (4) and a circuit board layer (5), which are sequentially arranged in a direction away from the other one of the first detection plate and the second detection plate, the detection layer (3) comprises a plurality of detection units (31) arranged in an array manner, each detection unit (31) comprises a plurality of scintillation crystals (311), and the signal reading layer (4) comprises a silicon photomultiplier (411); and a data processing device electrically connected to a circuit board layer (5). The first detection plate (21) and the second detection plate (22) are configured to be capable of moving towards and away from each other and being positioned, such that the distance between the first detection plate and the second detection plate may be adjusted.

Description

PET testing equipment

Cross reference of related applications

This application requires that it be submitted to the China Patent Office on September 2, 2019, with the application number 201910824562.0, and the name is "a PET testing equipment", and on September 2, 2019, the application number is 201921458834.1, and the name is The priority of the Chinese patent application for "a PET detection equipment", the entire content of which is incorporated in this application by reference.

Technical field

The present disclosure belongs to the field of medical equipment, and specifically relates to a PET detection equipment.

Background technique

PET (Positron Emission Tomography), or Positron Emission Tomography, is a relatively advanced clinical examination imaging technology in the field of nuclear medicine, and it is currently recognized as one of the most advanced large-scale medical diagnostic imaging technologies in the medical field. PET is a non-invasive nuclear medicine imaging method. Its principle is to use bioactive substances labeled with radionuclides (such as tracer drugs such as fluorodeoxyglucose) to participate in the physiological metabolism of organisms. According to the measurement of radionuclide Distribution in organisms, indirect observation of the metabolism and three-dimensional distribution of biologically active substances. At present, PET technology has been widely used in clinical examinations, including examinations for cancer, brain diseases, and heart disease.

The PET detection equipment is mainly composed of detectors, electronics systems and reconstruction algorithm modules. Among them, the detector detects the radioactive signal emitted from the human body, and after processing by the electronic system, the collected scan data is image-reconstructed to obtain a tomographic image of the human body, which can reflect the specific coordinate position, morphological structure and pathology of the lesion Physiological changes improve the accuracy of diagnosis.

However, the existing whole-body PET detection equipment is relatively large, and the scanning detection space enclosed by its detector is large and circular. When scanning data, the patient needs to lie on the detection bed and keep the body in the circular shape. The whole body data is collected and reconstructed in the space, which not only increases the scanning time, but also causes the processing of a lot of useless image data, thereby increasing the burden of data processing. In addition, the existing circular PET detection equipment also has defects such as limited detection operations due to the fixed position of the detector or limited detection space. Such PET detection equipment allows the patient to detect the affected area only in a specific posture, or only Part of the affected area can be placed in the detection space, which is not conducive to the comfort of patient detection and the collection of complete information and image reconstruction of the affected area, thereby affecting the comfort and accuracy of detection.

In view of the shortcomings of the prior art, those skilled in the art are eager to find a PET detection device with fast and accurate detection and flexible operation.

Summary of the invention

In order to make the detection more rapid and accurate, and the operation flexible, the present disclosure proposes a PET detection device.

The PET detection device according to the embodiment of the present disclosure includes: a base; a detection component connected to the base, the detection component is configured to at least be able to rotate and position relative to the base, and to move and position longitudinally relative to the base, wherein the detection component It includes a first detection board and a second detection board that are arranged oppositely and in parallel. Either one of the first detection board and the second detection board includes a detection layer and a signal reading board that are sequentially arranged in a direction away from the other. Take the layer and the circuit board layer, where the detection layer includes a plurality of detection units arranged in an array, each detection unit includes a plurality of scintillation crystals arranged in an array, and the signal reading layer includes one-to-one coupling with each scintillation crystal to read the scintillation crystals The silicon photomultiplier tube of the scintillation signal, the circuit board layer is used to fix each silicon photomultiplier tube and convert the scintillation signal read by each silicon photomultiplier tube into an electrical signal; and a data processing device electrically connected to the circuit board layer. Wherein, the first detection board and the second detection board in the detection assembly are arranged to be able to move and be positioned in directions toward and away from each other, so that the distance between the first detection board and the second detection board can be adjusted.

Further, the detection units are aligned along the horizontal and vertical directions of the detection layer, and each detection unit in the first detection board corresponds to each detection unit in the second detection board in a one-to-one correspondence.

Further, the detection units are arranged in equal numbers along the horizontal and vertical directions of the detection layer.

Further, a barrier layer for blocking radioactive rays is provided between adjacent detection units.

Further, the scintillation crystal includes a first crystal surface for coupling with the silicon photomultiplier tube, a second crystal surface opposite to the first crystal surface for forming a detection surface, and a connection between the first crystal surface and the second crystal surface. The side surface, wherein the side surface and the second crystal surface are provided with a first light reflecting layer.

Further, the first detection board and/or the second detection board further include a second light-reflecting layer that completely covers the side of the detection layer away from the circuit board layer.

Further, the detection assembly further includes a longitudinal adjusting arm slidably connected to the base and a rotating arm rotatably connected to the longitudinal adjusting arm, the first detecting plate and the second detecting plate are arranged in parallel and spaced apart on the rotating arm and slidably connected to the rotating arm .

Further, the rotating arm includes: a positioning guide plate, which is fixedly connected to the longitudinal adjustment arm, a plurality of guide wheels are arranged on the disc surface of the positioning guide plate at intervals in the circumferential direction, and an annular groove is formed on the outer peripheral edge of each guide wheel; Annular rotating disc. The inner peripheral edge of the annular rotating disc is matched with the annular grooves of the guide wheels at the same time, and the disc surface of the annular rotating disc is at least partially overlapped with the disc surface of the positioning guide disc to form an annular overlapping area, which is in the circumferential direction of the annular overlapping area A plurality of positioning holes penetrate through; and a positioning component. Among them, the first detection plate and the second detection plate are slidably connected with the annular rotating disk, and the positioning component makes the annular rotating disk rotate at different angles relative to the positioning guide plate by passing through different positioning holes, so that the annular rotating disk can simultaneously drive the first The first detection board and the second detection board rotate to different detection positions.

Further, a plurality of positioning holes are arranged at equal intervals.

Further, the annular rotating disk further includes a guiding and positioning sliding rod fixedly connected to the annular rotating disk, and the first detection plate and the second detecting plate are slidably connected to the guiding and positioning sliding rod.

Compared with the prior art, the PET detection device of the embodiment of the present disclosure has the following advantages:

1) The detection components of the PET detection equipment in the embodiments of the present disclosure can be operated more flexibly at the parts to be examined on the human body;

2) The plate-shaped design of the first detection board and the second detection board in the detection component of the PET detection device of the embodiment of the present disclosure that are arranged oppositely and in parallel makes the structure of the detection component simpler and can quickly detect any part of the human body , It is more flexible and pertinent to the parts to be inspected. Compared with the large ring-shaped inspection area in the prior art, it not only reduces the scanning time, but also avoids the processing of a lot of useless image data. This greatly reduces the processing load of the data processing device.

3) The adjustability of the position of the detection component of the PET detection device and the size of the detection area of the embodiment of the present disclosure makes the detection operation of the diseased part unrestricted, so that not only the collection of complete information of the affected area and the reconstruction of the image can be realized In order to improve the accuracy of the detection, the patient does not need to strictly detect the affected area in a specific posture, thereby improving the comfort of the patient's detection.

Description of the drawings

In order to more clearly illustrate the specific embodiments of the present disclosure or the technical solutions in the prior art, the following will briefly introduce the drawings that need to be used in the description of the specific embodiments or the prior art. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, each element or part is not necessarily drawn according to actual scale.

Fig. 1 is a schematic structural diagram of a PET detection device according to an embodiment of the present disclosure, wherein the PET detection device is in an initial state;

FIG. 2 is a schematic diagram of the structure of the PET detection device shown in FIG. 1, wherein the PET detection device is in a rotating state;

FIG. 3 is a schematic diagram of the structure of the PET detection device shown in FIG. 1, wherein the PET detection device is in a longitudinally moving state;

4 is a schematic cross-sectional view of the structure of the first detection board shown in FIG. 1;

5 is a front view of the internal structure of the first detection board shown in FIG. 1;

6 is a schematic cross-sectional view of the structure of the detection unit shown in FIG. 5;

Fig. 7 is a schematic structural view of the first embodiment of the rotating arm shown in Fig. 1;

Figure 8 is an axonometric side view of the rotating arm shown in Figure 7;

FIG. 9 is a schematic diagram of the structure of the guide wheel shown in FIG. 7;

Fig. 10 is a schematic structural diagram of a second embodiment of the rotating arm shown in Fig. 1;

FIG. 11 is a tomographic stereo image of the breast processed by the PET detection device of an embodiment of the present disclosure, which shows the stereo image when the detection position of the human body is directly aligned;

FIG. 12 is a tomographic stereo image of the breast processed by the PET detection device of the embodiment of the present disclosure, which shows the stereo image when the detection position of the human body is the oblique lateral position;

Fig. 13 is a plan view of the tomographic three-dimensional image shown in Fig. 12, which shows a lesion in a part of a human body to be inspected.

detailed description

The embodiments of the technical solution of the present disclosure will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solutions of the present disclosure, and therefore are only used as examples, and cannot be used to limit the protection scope of the present disclosure.

FIGS. 1-3 show the structure of the PET detection device 100 according to an embodiment of the present disclosure, which respectively show schematic diagrams of the PET detection device 100 according to an embodiment of the present disclosure in an initial state, a rotating state, and a longitudinal movement state. As shown in FIG. 1, the PET detection device 100 includes: a base 1; a detection assembly 2 connected to the base 1, and the detection assembly 2 is set to at least be able to rotate and position relative to the base 1 (rotation as shown in FIG. State), and longitudinally moved and positioned relative to the base 1 (as shown in the longitudinal movement state of FIG. 3), wherein the detection assembly 2 includes a first detection board 21 and a second detection board 22 that are arranged oppositely and in parallel, as shown in FIG. 4 and 5, any one of the first detection board 21 and the second detection board 22 includes a detection layer 3, a signal reading layer 4, and a circuit board layer that are sequentially arranged in a direction away from the other. 5. The detection layer 3 includes a plurality of detection units 31 arranged in an array. As shown in FIG. 6, each detection unit 31 includes a plurality of scintillation crystals 311 arranged in an array, and the signal reading layer 4 includes a pair of scintillation crystals 311. A silicon photomultiplier tube 411 coupled to read the scintillation signal of the scintillation crystal 311, the circuit board layer 5 is used to fix each silicon photomultiplier tube 411 and convert the scintillation signal read by each silicon photomultiplier tube 411 into an electrical signal; and A data processing device (not shown in the figure) electrically connected to the circuit board layer 5. Wherein, the first detection board 21 and the second detection board 22 in the detection assembly 2 are arranged to be able to move and be positioned in directions toward and away from each other, so that the distance between the first detection board 21 and the second detection board 22 can be adjusted. Tune.

Preferably, the data processing device (not shown in the figure) may include a data processing module and a display module electrically connected to the data processing module. Among them, the data processing module may include an electronics system and a reconstruction algorithm module. After the radioactive signal emitted by the human body is processed by the electronic system, the collected scan data is image-reconstructed to display a clear cross-sectional image of the body to be inspected on the display module (as shown in Figure 11 to Figure 13 ). Also preferably, the data processing device can be integrated with the base 1 as a whole.

The PET detection device 100 of the embodiment of the present disclosure needs to inject a radionuclide (for example, fluorodeoxyglucose) into the human body before detecting the body to be inspected. The radionuclide (carrying positrons) can label the biological activity Substances participate in the physiological metabolism of organisms, so that most of them can be concentrated and marked on the lesions of the human body, that is, the affected parts of the human body. When the PET detection device 100 of the embodiment of the present disclosure detects the part of the human body to be inspected, first, by adjusting the detection assembly 2 to move and position it upward or downward along the longitudinal direction of the base 1, the first detection plate 21 can be connected to The detection area 23 formed between the second detection plate 22 (as shown in FIG. 1) can be moved to a height corresponding to the part of the human body to be examined. At this time, the part to be examined is located between the first detection plate 21 and the second detection plate 22 ; Then, by adjusting the first detection board 21 and the second detection board 22 to move and position in the direction toward and away from each other, the body part to be tested is placed between the first detection board 21 and the second detection board 22 Position; then the detection component 2 can be turned on for measurement and imaging of the part to be measured. At this time, the radionuclides in the human body will simultaneously emit positrons toward the first detection board 21 and the second detection board 22, wherein the first detection board 21 and the second detection board 22 The detection layer 3 (ie, the multiple scintillation crystals 311) in the second detection board 22 can receive these positrons, and at the same time, the signal reading layer 4 (ie, the silicon photomultiplier tube 411) can amplify and read the scintillation crystals 311. The flicker signal is then converted into an electrical signal by the signal processing circuit (not shown in the figure) in the circuit board layer 5. The electrical signal is finally processed and imaged by the data processing device, and the image is analyzed, In order to obtain the detection result of this detection position; finally, by adjusting the rotation and positioning of the detection assembly 2 relative to the base 1 to obtain other detection positions of the human body to be examined, the detection results of other detection positions can be obtained. The measurement process and principle of other detection positions are the same as the above-mentioned process and principle, and will not be repeated here.

Compared with the prior art, the PET detection device 100 of the embodiment of the present disclosure has the following advantages:

1) The PET detection device 100 of the embodiment of the present disclosure can move and be positioned longitudinally relative to the base 1 by setting the detection component 2 and can rotate and be positioned relative to the base 1, so that the detection component 2 can be operated more flexibly on the human body. At the site to be inspected;

2) The plate-shaped design of the first detection board 21 and the second detection board 22 in the detection component 2 of the PET detection device 100 of the embodiment of the present disclosure that are arranged oppositely and in parallel makes the structure of the detection component 2 simpler and easier to adjust and use Convenient, and the design of the detection layer 3, the signal reading layer 4, and the circuit board layer 5 inside the first detection board 21 and the second detection board 22 can quickly and accurately receive the corresponding signals in the human body and process the signals to Through the data processing device finally accurately locate the position and coordinates of the diseased part of the human body to be inspected, the above-mentioned design of the present disclosure can quickly detect any part of the human body, and it is more flexible and pertinent to the parts that need to be detected Compared with the large ring detection area in the prior art, it not only reduces the scanning time, but also avoids the processing of a lot of useless image data, thereby greatly reducing the processing load of the data processing device, which is essentially At a lower cost, the PET inspection equipment 100 can detect the parts to be inspected more quickly, accurately, and flexibly;

3) The adjustability of the position of the detection component 2 of the PET detection device 100 and the size of the detection area 23 of the embodiment of the present disclosure makes the detection operation of the diseased part unrestricted, thereby not only realizing the collection of complete information of the affected area and The reconstruction of the image can improve the accuracy of the detection, and the patient does not need to strictly detect the affected area in a specific posture, thereby improving the comfort of the patient's detection.

It should be noted here that since the scintillation crystal 311 is usually constructed in a cubic structure, the detection unit 31 constructed by a plurality of scintillation crystals 311 is also usually square, and the signal reading layer 4 and the circuit board layer 5 are actually respectively. It is composed of a plurality of square silicon photomultiplier tube groups and square circuit boards arranged at intervals. That is to say, the first detection board 21 and the second detection board 22 of the present application are actually formed by a plurality of square detection components including a detection unit 31, a silicon photomultiplier tube group, and a circuit board arranged at intervals. The data processing module in the data processing device of the present application is actually electrically connected to a single detection component (that is, including a single detection unit 31, a silicon photomultiplier tube group, and a circuit board) through an electronic system, and The data of the circuit boards are collected separately and sent to the reconstruction algorithm module for image reconstruction, and finally a clear cross-sectional image of the part to be inspected of the human body is displayed on the display module.

In the preferred embodiment shown in FIGS. 4 and 5, the detection units 31 can be aligned along the horizontal and vertical directions of the detection layer 3. Each detection unit 31 in the first detection board 21 and the second detection board 22 Each detection unit 31 of the corresponding one-to-one correspondence. The “one-to-one correspondence” should be understood as the detection units 31 in the first detection board 21 and the opposite detection units 31 in the second detection board 22 are completely facing each other. This arrangement makes the detection units in the first detection board 21 The scintillation crystals 311 in each detection unit 31 opposite to the second detection plate 22 can simultaneously receive radioactive signals generated at the same point (or the same position) of the human body. In this way, not only can the silicon photomultiplier tube 411 react to the scintillation crystal The 311 spectroscopic positioning is easier, and it can also avoid miscoding caused by receiving radioactive signals from different positions, thereby effectively reducing the probability of mislocalization of the lesion. In addition, the above settings also help to improve the resolution and clarity of the imaging of the transverse section of the site to be inspected, thereby further improving the accuracy of disease diagnosis.

In a preferred embodiment, the side wall of the first detection board 21 may be provided with a first measuring arm 211 (as shown in FIG. 1) that can extend and contract in a direction perpendicular to the second detection board 22, and the second A second measuring arm 221 (as shown in FIG. 1) capable of extending and retracting in a direction perpendicular to the first detecting plate 22 may be formed on the side wall of the detecting plate 22. The extending direction of the first measuring arm 211 is the same as the second measuring arm 211. The telescopic directions of the arms 221 are located in the same plane. With this arrangement, when the part of the human body to be inspected is located between the first inspection board 21 and the second inspection board 22, the extension lengths of the first measurement arm 211 and the second measurement arm 221 are adjusted to be equal, and they are respectively the same as those to be inspected. The position abuts, the body part to be inspected can be located in the middle position between the first inspection board 21 and the second inspection board 22, so that the detection unit 31 on the first inspection board 21 and the second inspection board 22 can receive at the same time The distance to the radioactive signal is the same, thereby reducing the amount of data processing and improving the efficiency of data processing.

According to the present disclosure, in the preferred embodiment shown in FIG. 5, the detection units 31 can be arranged in equal numbers along the horizontal and vertical directions of the detection layer 3. Such an arrangement can make the cross-cut layer image of the part to be inspected form a cube. Structure (combined with Figure 11), the cross-sectional image of the cube structure can not only better cover the part of the human body to be examined, so as to ensure the integrity of the imaging of the part of the human body to be examined, but also help to improve the cross-cut layer of the cube The efficiency of image processing and analysis helps to improve the imaging quality of the body to be inspected.

In a preferred embodiment, the detection layer 3 may include 4 rows and 4 columns of detection units 31 formed along the transverse and longitudinal directions of the detection layer 3. Further, the detection unit 31 may include a plurality of scintillation crystals 311 arranged in an array of "12 rows x 12 columns". Such an arrangement can achieve higher resolution and clarity of imaging the transverse section image at a lower cost. . Of course, the number of the detection units 31 arranged along the horizontal and vertical directions of the detection layer 3 can be specifically set according to actual needs, which is not limited here.

According to the present disclosure, in order to improve the imaging quality of the transverse section image and improve the accuracy of the PET detection device 100 of the present disclosure in diagnosing the diseased part, the detection unit 31 may be improved as follows:

In a preferred embodiment, as shown in FIG. 5, a barrier layer 33 for blocking radioactive rays may be provided between adjacent detection units 31. The PET detection device 100 of the embodiment of the present disclosure can effectively reduce or prevent the radioactive signal emitted from the human body between the scintillation crystals 311 of the adjacent detection units 31 by providing the barrier layer 33 between the adjacent detection units 31 The generated scattering phenomenon can avoid the signal crosstalk between adjacent detection units 31, thereby effectively avoiding the influence of scattering on the judgment of the lesion position, which helps to improve the imaging quality of the transverse section image imaging, thereby improving The accuracy of the PET detection device 100 in the embodiment of the present disclosure in diagnosing the diseased part. Preferably, the barrier layer 33 may be a black paint layer (not shown in the figure) sprayed on the sidewalls of the scintillation crystal 311, or a black covering (not shown in the figure), or as shown in FIG. A black partition 331 is provided between the detection units 31.

In another preferred embodiment, as shown in FIG. 6, the scintillation crystal 311 may include a first crystal surface 312 for coupling with the silicon photomultiplier tube 411 and a detection surface opposite to the first crystal surface 312. The second crystal surface 313, and the side surface 314 connecting the first crystal surface 312 and the second crystal surface 313. Wherein, the side surface 314 and the second crystal surface 313 may be provided with a first reflective layer 315. With this arrangement, the first reflective layer 315 can also reduce the signal crosstalk between the scintillation crystals 311, thereby further improving the imaging quality of the cross-sectional image, thereby improving the accuracy of the PET detection device 100 of the present disclosure in the diagnosis of the diseased part. Sex. Preferably, the first reflective layer 315 may be one or more of a pasted reflective film, a sprayed reflective material, and a reflective plating layer.

In another preferred embodiment, the first detection board 21 and/or the second detection board 22 may further include a second reflective layer (not shown in the figure) that completely covers the side of the detection layer 3 away from the circuit board layer 5. ). The arrangement of the second reflective layer can not only further reduce the signal crosstalk between the scintillation crystals 311, but also facilitate its rapid installation and use; at the same time, this arrangement does not need to separately set the first scintillation crystal 311 for each scintillation crystal 311 as in the previous embodiment. A reflective layer 315, which effectively reduces the production cost of the detection layer 3.

Returning to FIG. 1, according to the present disclosure, the detection assembly 2 may further include a longitudinal adjustment arm 6 slidably connected with the base 1 and a rotating arm 7 rotatably connected with the longitudinal adjustment arm 6, a first detection plate 21 and a second detection plate 22 It is arranged on the rotating arm 7 in parallel and spaced apart and slidably connected with the rotating arm 7. With this arrangement, the two operations of moving and positioning the detection assembly 2 up or down along the longitudinal direction of the base 1 and rotating and positioning relative to the base 1 can be performed separately, which can effectively improve the flexibility of the operation of the detection assembly 2 Sex.

Preferably, as shown in Figs. 7 and 8, the rotating arm 7 may include: a positioning guide plate 71, which is fixedly connected to the longitudinal adjustment arm 6, and the positioning guide plate 71 is arranged at intervals in the circumferential direction on the disc surface. There are two guide wheels 72, and the outer peripheral edge of each guide wheel 72 is formed with an annular groove 721 (as shown in FIG. 9); the annular rotating disc 73, the inner peripheral edge of the annular rotating disc 73 is simultaneously matched with the annular groove 721 of each guide wheel 72 , And the disk surface of the annular rotating disk 73 at least partially overlaps with the disk surface of the positioning guide disk 71 to form an annular overlapping area. A plurality of positioning holes 74 penetrate through the annular overlapping area in the circumferential direction; and positioning components (not shown in the figure). Wherein, the first detection plate 21 and the second detection plate 22 are slidably connected to the annular rotating disk 73, and the positioning component passes through different positioning holes 74 to make the annular rotating disk 73 rotate at different angles relative to the positioning guide plate 71 to make the annular The rotating disc 73 can simultaneously drive the first detection board 21 and the second detection board 22 to rotate to different detection positions.

Specifically, the positioning guide plate 71 can be fixed on the longitudinal adjustment arm 6 by bolts, and the guide wheel 72 is rotatably connected with the plate surface of the positioning guide plate 71 so that the guide wheel 72 can rotate by itself. The annular groove 721 of each guide wheel 72 cooperates so that the inner peripheral edge of the annular rotating disk 73 can be confined in the annular groove 721 and can be rotated relative to the positioning guide plate, thereby realizing the adjustment of the detection assembly 2 relative to the longitudinal adjustment arm 6 rotation angle. After rotating to the required angle (ie, the required detection position), a positioning component, such as a positioning pin, is inserted into the positioning hole 74 to realize the positioning of the annular rotating disk 73 relative to the positioning and guiding disk 71. Through this arrangement, the adjustment method of the detection assembly 2 of the present disclosure when adjusting the required angle is simpler and more flexible, thereby facilitating the operation of the operator. At the same time, the rotating arm has a simple structure and is easier to manufacture, which can effectively reduce production costs.

Preferably, as shown in FIG. 7, a plurality of positioning holes 74 may be arranged at equal intervals to adjust the rotation angle of the annular rotating disk 73 at an equal angle. Preferably, the interval angle between adjacent positioning holes 74 ranges from 5° to 45°, preferably 5°. With this arrangement, the annular rotating disk 73 can realize the fine adjustment of the rotation angle that drives the rotation of the detection assembly 2 and realize the rapid positioning of the detection assembly 2, thereby improving the adjustment accuracy of the annular rotating disk 73, that is, the detection position Adjustments are more diverse.

Of course, the rotating arm 7 of the embodiment of the present disclosure can also realize automatic rotation and positioning. In another embodiment as shown in FIG. 10, the rotating arm 7 can include: an annular rotating disk 73a, and a disk surface perpendicular to the annular rotating disk 73a. And a rotating shaft 731 connected to the annular rotating disk 73a, a first gear 732 sleeved on the rotating shaft 731, a second gear 733 meshing with the first gear 732, and a motor 734 connected to the second gear 733 to control its rotation; The first detection plate 21 and the second detection plate 22 are slidably connected to the circular rotating disk 73a, and the motor 734 is electrically connected to the control system. The control system can control the motor 734 to rotate at a predetermined angle to drive the circular rotating disk 73a to rotate at a certain angle. In this way, the automatic rotation function of the annular rotating disk 73a is realized, and the accuracy and convenience of the operator's control are further improved. In addition, in addition to the annular rotating disk 73, the rotating shaft 731, the first gear 732, the second gear 733, and the motor 734 can all be arranged inside the longitudinal adjustment arm 6 to improve the aesthetics of the PET inspection device 100 of the present disclosure.

According to the present disclosure, the rotating arm 7 may further include a guiding and positioning sliding rod 8 (shown in conjunction with FIG. 1) fixedly connected to the annular rotating disk 73, and the first detecting plate 21 and the second detecting plate 22 are slidably connected to the guiding and positioning sliding rod 8. , In order to realize that the distance between the first detection board 21 and the second detection board 22 is adjustable. Preferably, the guiding and positioning sliding rod 8 can be a linear guide rail. The linear guide rail may include a slideway fixedly connected to the annular rotating disk 73 and two sliding blocks slidably connected to the slideway, and the first detection board 21 and the second detection board 22 are respectively fixedly connected to the slide blocks. Among them, the linear drive motor in the linear guide can control the slider to slide along the slideway and stop at a preset position, so that the first detection board 21 and the second detection board 22 can be guided and positioned along the slide bar 8 to achieve Movement and positioning away from each other. With this arrangement, the stability of the movement of the first detection board 21 and the second detection board 22 can be improved.

Figures 11-13 show tomographic three-dimensional images of a woman's right breast detected at different detection positions by the PET detection device 100 of an embodiment of the present disclosure, and Figure 11 is a tomographic scan when the detection position of a woman is directly aligned In a stereo image, the right alignment can be understood as the position of the detection component 2 relative to the base 1 as shown in FIG. 3, the female faces the detection component 2 and the right breast is placed in the detection area 23 of the detection component 2. Figure 12 is a tomographic three-dimensional image when the detection position of a woman is in an oblique lateral position. The oblique lateral position can be understood as based on the position of the detection component 2 relative to the base 1 in Figure 1, and the detection component 2 is inverted relative to the base 1. The hour hand is rotated by 45°, so that the detection area 23 of the detection assembly 2 can detect a part of the stereoscopic image of the female armpit. Figure 13 is a plan view of the tomographic stereo image shown in Figure 12, in which a comprehensive observation and comparison of the orthographic tomographic stereo image and the oblique lateral tomographic stereo image is obtained, and the oblique lateral tomographic stereo image ( As shown in Figure 12), a clearer display of the lesion can be obtained, and a plan view with the better imaging quality (that is, the most clear lesion display) in the oblique lateral tomography stereo image has been selected (as shown in Figure 13) , The plan view intuitively reflects the size of the lesion 9a in the human body (3.47cm as shown in Figure 13) and the relative position and specific coordinates 9b (the coordinates as shown in Figure 13 are X: 69.08mm Y :160.00mm Z:161.69mm), by taking multiple measurements on the patient within a certain time interval, you can also observe the pathological changes of the affected area, understand the treatment effect, and decide whether to adjust and optimize the treatment measures according to the situation, so as to avoid inefficiency Occurrence of medication, excessive medication, etc.

It should be noted that, unless otherwise specified, the technical terms or scientific terms used in this application shall have the usual meanings understood by those skilled in the art to which this disclosure belongs.

In the description of this application, it should be understood that the orientation or positional relationship indicated by the terms "longitudinal", "forward", "reverse", etc. are based on the orientation or positional relationship shown in the drawings, and is only for ease of description The present disclosure and simplified description do not indicate or imply that the device or element referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore cannot be understood as a limitation of the present disclosure.

In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. In the description of the present disclosure, "plurality" means two or more, unless otherwise specifically defined.

Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present disclosure, not to limit it; although the present disclosure has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: The technical solutions recorded in the foregoing embodiments can still be modified, or some or all of the technical features can be equivalently replaced; these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the technical solutions of the embodiments of the present disclosure. Scope, all of which shall be included in the scope of the claims and specification of the present disclosure. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any manner. The present disclosure is not limited to the specific embodiments disclosed in the text, but includes all technical solutions falling within the scope of the claims.

Claims

A PET detection equipment, which is characterized in that it comprises:

Base

A detection component connected to the base, the detection component being configured to at least be able to rotate and be positioned relative to the base, and move and be positioned longitudinally relative to the base,

Wherein, the detection assembly includes a first detection board and a second detection board that are arranged oppositely and in parallel, and any one of the first detection board and the second detection board includes an edge that is far away from the other. The detection layer, the signal reading layer and the circuit board layer are arranged in sequence in the direction,

Wherein, the detection layer includes a plurality of detection units arranged in an array, each of the detection units includes a plurality of scintillation crystals arranged in an array, and the signal reading layer includes one-to-one coupling with each of the scintillation crystals to read out all the scintillation crystals. The silicon photomultiplier tube for the scintillation signal of the scintillation crystal, and the circuit board layer is used to fix each silicon photomultiplier tube and convert the scintillation signal read by each silicon photomultiplier tube into an electrical signal; and

A data processing device electrically connected to the circuit board layer;

Wherein, the first detection board and the second detection board in the detection assembly are arranged to be able to move and be positioned in directions toward and away from each other, so that the first detection board and the second detection board The spacing between is adjustable.
The PET detection device according to claim 1, wherein each of the detection units is aligned along the horizontal and vertical directions of the detection layer, and each detection unit in the first detection board is aligned with the second detection board. Each detection unit in the corresponding one-to-one.
The PET detection device according to claim 2, wherein each of the detection units is arranged in equal numbers along the horizontal and vertical directions of the detection layer.
The PET detection device according to any one of claims 1 to 3, wherein a barrier layer for blocking radioactive rays is provided between adjacent detection units.
The PET detection device according to any one of claims 1 to 3, wherein the scintillation crystal includes a first crystal surface for coupling with the silicon photomultiplier tube and a first crystal surface opposite to the first crystal surface. The second crystal surface for forming the detection surface, and the side surface connecting the first crystal surface and the second crystal surface, wherein the side surface and the second crystal surface are provided with a first reflector Floor.
The PET detection device according to any one of claims 1 to 3, wherein the first detection board and/or the second detection board further comprises a circuit board that completely covers the detection layer and is far away from the circuit board. The second reflective layer on one side of the layer.
The PET detection equipment according to any one of claims 1 to 3, wherein the detection assembly further comprises a longitudinal adjustment arm slidably connected with the base and a rotating arm rotatably connected with the longitudinal adjustment arm , The first detection board and the second detection board are arranged on the rotating arm in parallel and spaced apart and slidably connected with the rotating arm.
The PET detection equipment according to claim 7, wherein the rotating arm comprises:

A positioning guide plate, the positioning guide plate is fixedly connected with the longitudinal adjustment arm, a plurality of guide wheels are arranged on the disc surface of the positioning guide plate at intervals in the circumferential direction, and an annular groove is formed on the outer peripheral edge of each guide wheel ；

An annular rotating disc, the inner peripheral edge of the annular rotating disc is simultaneously matched with the annular groove of each of the guide wheels, and the disc surface of the annular rotating disc at least partially overlaps with the disc surface of the positioning guide disc to form an annular overlapping area , A plurality of positioning holes penetrate through the circumferential direction of the annular overlapping area; and

Positioning parts,

Wherein, the first detection plate and the second detection plate are slidably connected to the annular rotating disk, and the positioning member makes the annular rotating disk relative to the positioning guide plate by passing through different positioning holes. Rotate at different angles, so that the ring-shaped rotating disk can simultaneously drive the first detection plate and the second detection plate to rotate to different detection positions.
8. The PET detection equipment according to claim 8, wherein a plurality of the positioning holes are arranged at equal intervals.
The PET inspection device according to claim 8 or 9, wherein the annular rotating disk further comprises a guiding and positioning sliding rod fixedly connected with the annular rotating disk, and the first detecting plate and the second detecting plate The plate is slidably connected to the guiding and positioning sliding rod.