WO2021030361A1 - Appareil d'implant chirurgical - Google Patents

Appareil d'implant chirurgical Download PDF

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Publication number
WO2021030361A1
WO2021030361A1 PCT/US2020/045788 US2020045788W WO2021030361A1 WO 2021030361 A1 WO2021030361 A1 WO 2021030361A1 US 2020045788 W US2020045788 W US 2020045788W WO 2021030361 A1 WO2021030361 A1 WO 2021030361A1
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WO
WIPO (PCT)
Prior art keywords
surgical implant
implant apparatus
eye
laser energy
blade
Prior art date
Application number
PCT/US2020/045788
Other languages
English (en)
Inventor
Howard Jay KAPLAN
Original Assignee
Kaplan Howard Jay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaplan Howard Jay filed Critical Kaplan Howard Jay
Publication of WO2021030361A1 publication Critical patent/WO2021030361A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F9/00821—Methods or devices for eye surgery using laser for coagulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00865—Sclera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00868—Ciliary muscles or trabecular meshwork

Definitions

  • Exemplary embodiments of the subject disclosure relate generally to the field of medical device implant tools. Specifically, the subject disclosure relates to a device for preparing an eye to receive a surgical implant.
  • a surgical implant is a medical device designed to be implanted into a patient’s body.
  • a surgical implant may be adapted to be implanted into a vitreous humor of a patient’s eye and deliver one or more doses of a drug without a need for repeated intravitreal injections.
  • a non-limiting example of such surgical implant is the Port Delivery System surgical implant offered by Genentech, Inc. headquartered in San Francisco, California, United States. More recently, these implants have seen broadened use, for example in the delivery of anti-vascular endothelial growth factor (anti-VEGF) therapies as used for management of neovascular, or “wet,” age-related macular degeneration or other vascular diseases of the eye.
  • anti-VEGF anti-vascular endothelial growth factor
  • One surgical procedure to insert such an implant involves making an incision with a surgical blade and inserting the implant.
  • One disadvantage of such surgical procedure is an increased rate of vitreous hemorrhage in the eye, e.g., leaking of blood into the vitreous humor following the surgical procedure.
  • a modification to the surgical implantation procedure involves dissection of the sclera of the eye (e.g., the “white” of the eye) to the pars plana region to expose the uveal layer of the eye, and laser coagulation to cauterize the exposed uveal layer prior to making an incision with a surgical blade to enter the vitreous for subsequent insertion of the surgical implant.
  • an argon laser (/. e. , having a yellow, green, or blue wavelength) has been used to cauterize an exposed uvea.
  • a disadvantage of such modified surgical procedure is that scleral dissection to expose the uveal layer of the eye requires a specialized blade to dissect the sclera or conjunctiva and expose the uveal layer for cauterization. Such scleral dissection is also challenging and time consuming for even skilled surgeons to perform, and the specialized blade used to dissect the sclera is different and separate from the surgical blade used to enter the vitreous.
  • Exemplary embodiments of the present disclosure include a surgical implant apparatus.
  • the apparatus includes a plurality of optical fiber probes and a body.
  • the plurality of optical fiber probes are aligned with a longitudinal axis of the surgical implant apparatus and adapted to transmit laser energy through an outer surface of a sclera of an eye along the longitudinal axis to a uvea of the eye.
  • the body includes a distal end having a probe.
  • the probe has a contoured surface, an alignment edge, and one or more lateral edges extending from the alignment edge.
  • the alignment edge defines a boundary of the contoured surface and is adapted to engage an arc length of a limbus of the eye.
  • the one or more lateral edges include one or more boss members adapted to indent the outer surface of the sclera to provide reference marks on the outer surface of the sclera for use in positioning a blade for making an incision in the sclera.
  • the laser energy includes infrared laser energy.
  • the laser energy is transmitted from a pulsed 805 nm to 810 nm diode laser.
  • the laser energy is therapeutically sufficient to photocauterize an arcuate region in the uvea of the eye.
  • the plurality of optical fiber probes include four optical fiber probes spaced linearly apart by about 0.4 mm to about 0.6 mm.
  • the four optical fiber probes are spaced linearly apart by about 0.5 mm.
  • the body further includes a proximal end having a blade.
  • the blade has a width of about 3.0 mm to about 3.5 mm.
  • the blade has a width of about 3.2 mm.
  • the blade is a keratome blade.
  • the blade is formed from metal, silicone, sapphire, or diamond.
  • the blade is retractable.
  • the proximal end of the body further includes a grip.
  • the proximal end of the body further includes a fitted cap adapted to cover the blade.
  • the boss members are spaced from the alignment edge by at least about 3 mm.
  • the boss members are spaced from the alignment edge by about 4 mm.
  • the plurality of optical fiber probes are disposed from the alignment edge by about 3.75 mm to about 4.25 mm.
  • the plurality of optical fiber probes are disposed from the alignment edge by about 4 mm.
  • the body further includes a proximal end having one or more fiber-optic connectors or fiber-optic cables.
  • the contoured surface has a single radius of curvature.
  • the contoured surface is adapted for conforming engagement with the surface of the sclera of the eye.
  • the one or more lateral edges include two lateral edges each extending perpendicular to the alignment edge.
  • the arc length is in a range from about 5 degrees to about 30 degrees.
  • the arc length is about 10 degrees.
  • the alignment edge is concave having a radius of about 5.25 mm to about 6 mm.
  • a method of treatment for an eye includes positioning the surgical implant apparatus in contact with the outer surface of the sclera of the eye so that the probe of the surgical implant apparatus is oriented toward a pars plana region of the eye, and directing a therapeutically sufficient amount of laser energy from the probe of the surgical implant apparatus along the longitudinal axis through the outer surface of the sclera toward the pars plana region into a uvea of the eye to photocauterize a region in the uvea.
  • the method further includes making an incision into the photocauterized region of the uvea to prepare the eye for receiving a surgical implant.
  • the making the incision includes aligning a blade of the surgical implant apparatus using one or more visual reference marks imparted on the outer surface of the sclera from one or more boss members of the surgical implant apparatus.
  • the positioning the surgical implant apparatus includes aligning the probe adjacent the limbus of the eye.
  • the aligning the probe includes aligning the alignment edge of the probe adjacent the limbus.
  • the directing the therapeutically sufficient amount of laser energy includes directing the laser energy about 4 mm from the limbus into the pars plana region of the eye.
  • the directing the therapeutically sufficient amount of laser energy includes directing the laser energy using power settings of about 1250 mW to about 2250 mW.
  • the directing the therapeutically sufficient amount of laser energy includes activating the laser energy from about 2 seconds to about 4 seconds.
  • the directing the therapeutically sufficient amount of laser energy comprises directing the laser energy for a duty cycle of about 31%.
  • the laser energy includes infrared laser energy.
  • the laser energy is transmitted from a pulsed 805 nm to 810 nm diode laser.
  • Exemplary embodiments of the present disclosure also include a method of treatment for an eye.
  • the method includes positioning a surgical implant apparatus in contact with an outer surface of a sclera of an eye so that a contact probe of the surgical implant apparatus is oriented toward a pars plana region of the eye, and directing a therapeutically sufficient amount of laser energy from the contact probe of the surgical implant apparatus along a longitudinal axis through the outer surface of the sclera toward the pars plana region into a uvea of the eye to photocauterize a region in the uvea.
  • the method further includes making an incision into the photocauterized region of the uvea to prepare the eye for receiving a surgical implant.
  • the making the incision includes aligning a blade of the surgical implant apparatus using one or more visual reference marks imparted on the outer surface of the sclera from one or more boss members of the surgical implant apparatus.
  • the positioning the surgical implant apparatus includes aligning a contact probe of the surgical implant apparatus adjacent the limbus of the eye.
  • the aligning the contact probe includes aligning an alignment edge of the contact probe adjacent the limbus.
  • the directing the therapeutically sufficient amount of laser energy includes directing the laser energy about 4 mm from the limbus into the pars plana region of the eye.
  • the directing the therapeutically sufficient amount of laser energy includes directing the laser energy using power settings of about 1250 mW to about 2250 mW.
  • the directing the therapeutically sufficient amount of laser energy includes activating the laser energy from about 2 seconds to about 4 seconds.
  • the directing the therapeutically sufficient amount of laser energy comprises directing the laser energy for a duty cycle of about 31%.
  • the laser energy includes infrared laser energy.
  • the laser energy is transmitted from a pulsed 805 nm to 810 nm diode laser.
  • FIG. 1 is a perspective view of a distal end of a surgical implant device in accordance with an exemplary embodiment of the subject disclosure
  • FIG. 2 is a perspective view of a surgical implant device in accordance with an alternative exemplary embodiment of the subject disclosure
  • FIGS. 3A-3B illustrate a method of treating the eye using a surgical implant device in accordance with exemplary embodiments of the subject disclosure.
  • FIG. 4 illustrates an example flowchart of a method of treating the eye using a surgical implant device in accordance with exemplary embodiments of the subject disclosure.
  • distal end of the present device refers to the end of the device towards the contact probe and the “proximal end” of the present device refers to the end of the device towards an optional fiber optic connector or blade.
  • proximal end refers to the end of the device towards an optional fiber optic connector or blade.
  • FIGS. 1A and 1B illustrate an exemplary embodiment of a surgical implant apparatus 100.
  • the apparatus 100 is adapted for preparing an eye to receive a surgical implant and includes a plurality of optical fiber probes 104 and a body 110.
  • the optical fiber probes 104 are aligned with a longitudinal axis of the surgical implant apparatus 100, e.g., the longitudinal axis A of the body 110.
  • the optical fiber probes extend substantially through a length of the body and are adapted to transmit infrared laser energy to and through the surface of the sclera of the eye, along the longitudinal axis.
  • the optical fiber probes allow the laser energy transmitted via the optical fiber probes to cauterize an arcuate region along and through the sclera of the eye wall, so as to penetrate and cauterize deep vascular tissue, e.g., in the uveal layer of the eye.
  • the arcuate region is curved along the pars plana and measures about 4 mm wide.
  • the apparatus 100 includes four optical fiber ports that are each spaced linearly apart from each other by a distance of about 0.4-0.6 mm, so as to cauterize the arcuate region.
  • the four optical fiber ports may be spaced linearly about 0.5 mm apart from each other so as to cauterize an arcuate region of about 4 mm.
  • a laser source 138 such as a diode laser source can transmit the laser energy via the optical fiber probes 104.
  • the laser source may be connected to the optical fiber probes.
  • the laser source may be provided from a separate console having fiber-optic ports 140 that are connectable to the optical fiber probes.
  • the connection may use fiber-optic cables or other fiber-optic connectors 136 that correspond to each optical fiber probe.
  • the laser energy can be infrared laser energy from a pulsed 805 nm-810 nm diode laser delivered to the pars plana region of the eye so as to photocauterize the uveal layer, the middle layer of eye tissue lying directly beneath the sclera, as described in further detail below.
  • the body 110 includes a distal end 120 and a proximal end 122.
  • the body may be an elongated member that is adapted to be handheld, for example by a surgeon or other medical provider preparing an eye to receive a surgical implant.
  • the axis of the body defines a longitudinal axis A (FIG.
  • a contact probe 102 is disposed on the distal end 120 of the body 110.
  • the contact probe includes a contoured surface 134, an alignment edge 106, and one or more lateral edges 112.
  • the contact probe may be formed from a substantially transparent or translucent material, so as to deliver laser energy effectively to the eye.
  • the contact probe may be formed from a transparent or translucent material such as Plexiglas, Lucite, or another acrylic resin sufficient to transmit laser energy to the eye.
  • the contoured surface 134 is adapted for substantially conforming and mating engagement with the curved outer surface of the sclera of the eye, when a user (for example, a surgeon or other medical provider) positions the contact probe over the sclera. Accordingly, the contoured surface may have a radius of curvature across the area of the contoured surface that conforms to the shape of the outer surface of the sclera at the limbus of the eye.
  • the alignment edge 106 defines a boundary of the contoured surface 134. Specifically, the alignment edge defines an arcuate contour that generally conforms to the limbus of the eye and is adapted to engage an arc length of the limbus.
  • the limbus refers to the region of the eye between the cornea and the sclera (e.g., the “white” of the eye).
  • the alignment edge can be generally circularly concave with a radius of about 5.25 mm-6.0 mm.
  • the alignment edge is adapted to act as a reference edge to facilitate placing the contact probe 102 such that the optical fiber probes 104 are disposed to deliver laser energy to and into the pars plana region of the eye, as illustrated in FIGS. 3A and 3B.
  • the optical fiber probes 104 may be disposed about 4 mm from the alignment edge for delivery of laser energy to photocauterize an arcuate region of the pars plana. This photocautery prepares the eye for subsequent incision with a blade followed by insertion of a surgical implant into the incision.
  • the lateral edges 112 extend from the alignment edge 106 and include one or more bosses or bumps 108.
  • the bosses which are sometimes referred to herein as bumps or boss members, are adapted to indent the surface of the sclera on either side of the arcuate region.
  • the indentations can provide one or more visual reference marks on the surface of the sclera, for use in aligning and positioning a blade for making an incision into the sclera and underlying uveal layer.
  • FIG. 2 illustrates an alternate exemplary embodiment of a surgical implant apparatus 200.
  • the apparatus 200 is adapted to prepare an eye to receive a surgical implant and includes a plurality of optical fiber probes 204 and a body 210.
  • the optical fiber probes 204 are arranged and operate substantially similarly to the optical fiber probes 104.
  • the optical fiber probes may connect to a laser source 238 that is connectable to one or more fiber-optic ports 240 via one or more fiber-optic cables or fiber-optic connectors 236, similar to the laser source 138 that is connectable to one or more fiber-optic ports 140 via one or more fiber-optic cables or fiber-optic connectors 136.
  • the fiber-optic cables 236 may connect near substantially a center or middle of the body 210.
  • the laser source 238 may be an infrared laser source such as a diode laser.
  • the body 210 includes a distal end 220 and a proximal end 222.
  • the distal end 220 includes a contact probe 202 that is arranged and operable substantially similarly to the contact probe 102.
  • the contact probe 202 has a contoured surface 234, an alignment edge 206, and one or more lateral edges 212 that are arranged and operable substantially similarly to the contoured surface 134, the alignment edge 106, and the one or more lateral edges 112, respectively.
  • the lateral edges 212 include one or more bosses or bumps 208 that are arranged and operable substantially similarly to the bosses 108.
  • a blade 218 is disposed on the proximal end 222 of the body 210.
  • the blade may have a width between 3.0 mm-3.5 mm, such as, for example, a 3.2 mm blade.
  • the blade may be a keratome blade.
  • the blade may be formed from, by way of non-limiting example, metal, silicone, sapphire, diamond, or any other material known to be appropriate to one of skill in the art for making an incision in the eye.
  • the blade can be retractable.
  • an actuator 214 coupled directly or indirectly to the blade may allow the user to use his or her thumb to move the actuator to extend or retract the blade.
  • the blade may be fixed and covered by a fitted cap or other protective covering.
  • a grip 216 may be disposed on the proximal end to facilitate a secure hold on the surgical implant apparatus 200.
  • FIGS. 3A, 3B, and 4 illustrate an exemplary method 400 of treating the eye using a surgical implant device.
  • the method prepares the eye to receive a surgical implant.
  • the method 400 includes positioning a surgical implant apparatus in contact with the eye (step 410).
  • the surgical implant apparatus may be the surgical implant apparatus 100 or 200.
  • the contact probe 102 is positioned so that the contoured surface 134 of the contact probe is in substantially conforming and mating contact with the outer surface of the sclera 326.
  • the alignment edge 106 is positioned adjacent the limbus 324 (FIGS. 3A and 3B), which refers to the region of the eye between the cornea 330 and the sclera 326, so that the optical fiber probes 104 are disposed to deliver laser energy to and through the surface of the sclera.
  • the contact probe and alignment edge may be positioned anywhere on the surface of the sclera adjacent the limbus that would be appropriate to deliver a therapeutically sufficient amount of laser energy to and through the sclera, for example, to the pars plana.
  • the user may place the alignment edge inferior to the cornea as shown in FIG. 3A, superior to the cornea (not shown), or anywhere else adjacent the limbus.
  • Longitudinal axis A of the body 110 forms a pre-determ ined angle 332, e.g., about 40°, relative to the optical axis B of the eye.
  • the optical fiber probes 104 may be disposed at a distance 328 of about 3.75 mm-4.25 mm, such as about 4 mm, from the alignment edge 106 for delivery of laser energy to photocauterize an arcuate region of the pars plana.
  • This photocautery prepares the eye for subsequent incision with a blade followed by insertion of a surgical implant into the incision.
  • photocauterizing the pars plana can lower the potential amount of undesired vitreous hemorrhaging that may occur upon incision of the photocauterized region with a blade.
  • the method 400 further includes directing a therapeutically sufficient amount of laser energy from the contact probe of the surgical implant apparatus along a longitudinal axis through the outer surface of the sclera toward the pars plana region into a uvea of the eye (step 420).
  • the user e.g., a surgeon or other medical provider
  • the power, time, and other treatment parameters for delivery of the laser energy may be pre-determ ined by the user. For example, the user may select power settings ranging from about 1250 mW to about 2250 mW for a duration from about 2 s to about 4 s.
  • the treatment parameters may also include a pulse duration and a pulse interval.
  • a “duty cycle” of about 31.3% may be used, which refers to an “on” time of about 0.5 ms and an “off” time of about 1.1 s per cycle, if the user determines that multiple cycles are necessary.
  • other treatment parameters for directing the laser energy are contemplated herein and may be pre determined by the user such that the amount of laser energy delivered to the pars plana by the transscleral laser is therapeutically sufficient to effect photocautery of the uveal layer, e.g., the middle layer of the eye lying beneath the sclera.
  • the bosses 108 along the lateral edges also indent the surface of the sclera so as to provide one or more visual reference markers for making an incision using a surgical blade, as described in further detail herein.
  • the laser source may include an “aiming beam” or “aiming mode.”
  • aiming beam the laser energy is insufficient to effect therapeutic photocautery but is sufficient to provide a visual indicator of where along the surface of the sclera the region of photocautery will result, upon delivery of the laser energy.
  • the method 400 further includes making an incision into the photocauterized region of the uvea to prepare the eye for receiving a surgical implant (step 430). Following photocauterization of the pars plana, the user prepares to make an incision to enter the vitreous of the eye using a surgical blade.
  • the user may flip the surgical implant device so that the contact probe 202 faces the user and the blade 218 faces the eye of the patient.
  • the user may actuate the actuator 214 to extend the retracted blade, or may remove the fitted cap to expose the fixed blade.
  • the user makes the incision to enter the vitreous. After making the incision, the eye is prepared to receive the surgical implant and the user may proceed to insert the surgical implant into the vitreous.
  • the various exemplary embodiments of the surgical implant device discussed herein provide numerous advantages over conventional surgical devices.
  • the present device uses a transscleral laser to effect photocautery safely and easily, without the need for a conventional dissection of the sclera or conjunctiva to expose the uveal layer for cauterization.
  • Such conventional dissection requires a separate specialized blade, and is challenging and time consuming even for skilled surgeons to perform.
  • an argon laser i.e., having a yellow, green, or blue wavelength, has been used to cauterize an exposed uvea, and not a transscleral infrared laser for penetrating the sclera without dissection.
  • a transscleral diode laser has conventionally been used only for glaucoma treatment, such as in micropulse transscleral cyclophotocoagulation treatment to relieve intraocular pressure in a glaucomatous eye.
  • micropulse transscleral cyclophotocoagulation the laser and photocoagulation result in destroying parts of the ciliary body of the eye that are responsible for production of aqueous humor, thereby reducing aqueous secretion and enhancing uveoscleral outflow, ultimately resulting in a decrease of intraocular pressure.
  • the present apparatus solves a different technical problem that otherwise requires conventional dissection of the sclera, and provides an entirely different use for a transscleral diode laser, to provide precise and configurable control over photocautery and prevention of vitreous hemorrhage in the eye.
  • Another advantage of the exemplary surgical implant device is the use and arrangement of the alignment edge, optical fiber probes, and bosses in the contact probe, e.g., alignment edge 106, 206, optical fiber probes 104, 204, and bosses 108, 208 in contact probe 102, 202, that provide for precise placement of the surgical implant device to deliver laser energy to the pars plana and minimize the amount of undesired vitreous hemorrhaging that might otherwise result.
  • the arrangement of the contact probe and the bosses also provide useful reference markers to aid the user in making a precise incision to enter the vitreous and prepare the eye to receive a surgical implant.
  • a further advantage of the exemplary surgical implant device embodiments is the combination of the contact probe with the blade, e.g., contact probe 202 and blade 218. This combination allows the user to minimize the amount of time that elapses from the completion of photocautery using the contact probe to making the incision with the blade and ultimately inserting the surgical implant.
  • substantially as used herein means considerable in extent, largely but not wholly that which is specified, or an appropriate variation therefrom as is acceptable within the field of art.
  • range format is merely for convenience and brevity and should not be construed as an inflexible limitation on the scope of the subject disclosure. Accordingly, the description of a range should be considered to have specifically disclosed all the possible subranges as well as individual numerical values within that range. For example, description of a range such as from 1 to 6 should be considered to have specifically disclosed subranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6 etc., as well as individual numbers within that range, for example, 1 , 2, 2.7, 3,

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Laser Surgery Devices (AREA)

Abstract

L'invention concerne des appareils et des procédés pour préparer un œil à recevoir un implant chirurgical. L'appareil comprend une pluralité de sondes à fibre optique et un corps. Les sondes à fibre optique sont alignées avec un axe longitudinal de l'appareil d'implant chirurgical et adaptées à transmettre une énergie laser à travers une surface extérieure d'une sclère d'un œil le long de l'axe longitudinal jusqu'à une uvéite de l'œil. Le corps comprend une extrémité distale ayant une sonde. La sonde comprend une surface profilée, un bord d'alignement et un ou plusieurs bords latéraux s'étendant à partir du bord d'alignement. Les bords latéraux comprennent un ou plusieurs éléments de bossage conçus pour entailler une surface externe d'une sclère de l'œil pour fournir des marques de référence sur la surface externe de la sclère pour une utilisation dans le positionnement d'une lame pour réaliser une incision dans la sclère.
PCT/US2020/045788 2019-08-12 2020-08-11 Appareil d'implant chirurgical WO2021030361A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962885400P 2019-08-12 2019-08-12
US62/885,400 2019-08-12

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WO2021030361A1 true WO2021030361A1 (fr) 2021-02-18

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4193974A1 (fr) * 2021-12-13 2023-06-14 Melek Mehmet Système de sonde de balayage laser transscléral ophtalmique

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6264668B1 (en) * 1998-09-16 2001-07-24 Arnold S. Prywes Ophthalmologic instrument for producing a fistula in the sclera
US20100076419A1 (en) * 2007-10-30 2010-03-25 Iridex Corporation Contact Probe for the Delivery of Laser Energy
US8277442B2 (en) * 2008-05-05 2012-10-02 Zila, Inc. Disposable tip apparatus for laser surgical device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6264668B1 (en) * 1998-09-16 2001-07-24 Arnold S. Prywes Ophthalmologic instrument for producing a fistula in the sclera
US20100076419A1 (en) * 2007-10-30 2010-03-25 Iridex Corporation Contact Probe for the Delivery of Laser Energy
US20150209179A1 (en) * 2007-10-30 2015-07-30 Iridex Corporation Contact probe for the delivery of laser energy
US8277442B2 (en) * 2008-05-05 2012-10-02 Zila, Inc. Disposable tip apparatus for laser surgical device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4193974A1 (fr) * 2021-12-13 2023-06-14 Melek Mehmet Système de sonde de balayage laser transscléral ophtalmique

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