WO2020233730A1 - Equipment for the collection of lung tissue in the endoscopic examination of the lungs - Google Patents
Equipment for the collection of lung tissue in the endoscopic examination of the lungs Download PDFInfo
- Publication number
- WO2020233730A1 WO2020233730A1 PCT/CZ2020/050031 CZ2020050031W WO2020233730A1 WO 2020233730 A1 WO2020233730 A1 WO 2020233730A1 CZ 2020050031 W CZ2020050031 W CZ 2020050031W WO 2020233730 A1 WO2020233730 A1 WO 2020233730A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- biopsy
- trap
- biopsy trap
- catheter
- blades
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/04—Endoscopic instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320725—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with radially expandable cutting or abrading elements
Definitions
- the present invention relates to a device for collecting lung tissue while minimizing the risk of bleeding or rupture of the lung during sampling of a lung parenchyma.
- bronchial biopsy where sampling from the peripheral part of the bronchial tree is performed using biopsy forceps (samples of the lung parenchyma are also obtained during the examination), as well as transbronchial lung cryobiopsy, which is a method for obtaining larger samples of the lung parenchyma using a special freezing probe (cryoprobe).
- the object of the invention is to provide a device for sampling the lung parenchyma which would substantially reduce the risks described.
- a lung parenchyma sampling device having a biopsy trap at the distal end and a biopsy trap control device at the proximal end.
- the biopsy trap is formed of at least three flexible flat blades located around a central portion formed by a catheter and provided with a rod for actuating the biopsy trap.
- the blades are firmly connected to the catheter at the distal end of the biopsy trap by means of a soft fixation element, the length of which is 1-5 mm, and serves as protection against pneu mothorax.
- the proximal end of the biopsy trap is formed by a proximal-distally movable anchor of the blade provided with a soft fixation element.
- the biopsy trap and the biopsy trap control device are connected by a catheter comprising a rod for con trolling the proximo-distal movement of the blade and a rotating catheter extension for controlling the rotation of the biopsy trap.
- the blades are made of austenitic or martensitic stainless steel of surgical grade or of a compound of nickel and titanium of surgical grade.
- the fixing elements are made of a photopolymerically cured medical resin.
- FIG.l illustrates a view of the biopsy trap in the open state
- FIG.2 illustrates a closed biopsy trap located in the working channel of the bron choscope
- FIG.3 illustrates the whole device with a closed biotic trap
- FIG.4 illustrates the whole device with an open biotic trap
- the lung parenchyma sampling device has a biopsy trap 1 at the distal end and a biopsy trap 1 control device 2 at the proximal end.
- the biopsy trap 1 is formed of four flexible flat blades 3 placed around a central part formed by a catheter 8 provided with a rod 5 for actuating the biopsy trap L
- the blades 3 are firmly connected to the catheter 8 at the distal end of the biopsy trap 1 by means of a soft fixation element 6a, the length of which is 1-5 mm and serves as protection against pneumothorax.
- the proximal end of the biopsy trap 1 is formed by a proximo-distally movable anchor 7 of the blade 3 provided with a soft fixation element 6b.
- the biopsy trap 1 and the control device 2 of the biopsy trap 1 are connected by a catheter 8 comprising a rod 5 for con trolling the proximo-distal movement of the blade 3 and a rotating attachment 9 of the catheter 8 for controlling the rotation of the biopsy trap 1.
- the blades 3 are made of austenitic steel in surgical quality.
- the fixing elements 6a, 6b are made of a resin usable in healthcare cured by photopolymerization.
- the lung parenchyma sampling device is inserted into the working channel of the bronchoscope 10, through which the biopsy trap 1 is introduced at the sampling site. By the action of the proximo-distal pressure by means of the rod 5, the blade 3 is compressed to a predefined diameter, whereby the biopsy trap 1 is opened by creating gaps between the individual blades 3.
- the open biopsy trap 1 is rotated, whereby a sample of the lung parenchyma is taken.
- the biopsy trap 1 closes, while the lung parenchyma sample remains inside the biopsy trap due to its porosity.
- the lung parenchyma sampling device has a biopsy trap 1 at the distal end and a biopsy trap 1 control device 2 at the proximal end.
- the biopsy trap 1 is formed of six flexible flat blades 3 placed around a central part formed by a catheter 8 provided with a rod 5 for actuating the biopsy trap 1.
- the blades 3 are firmly connected to the catheter 8 at the distal end of the biopsy trap 1 by means of a soft fixation element 6a, the length of which is 1-5 mm and serves as protection against pneumothorax.
- the proximal end of the biopsy trap 1 is formed by a proximo-distally movable anchor 7 of the blade 3 provided with a soft fixation element 6b.
- the biopsy trap 1 and the control device 2 of the biopsy trap 1 are connected by a catheter 8 comprising a rod 5 for con trolling the proximo-distal movement of the blade 3 and a rotating attachment 9 of the catheter 8 for controlling the rotation of the biopsy trap 1.
- the blades 3 are made of a compound of nickel and titanium in surgical quality.
- the fixing elements 6a, 6b are made of a resin usable in healthcare cured by photopolymerization.
- the lung parenchyma sampling device is inserted into the working channel of the bronchoscope 10, through which the biopsy trap 1 is introduced at the sampling site.
- the blade 3 By the action of the proximo-distal pressure by means of the rod 5, the blade 3 is compressed to a predefined diameter, whereby the biopsy trap 1 is opened by creating gaps between the individual blades 3.
- the open biopsy trap 1 By the action of the rotational force caused by the rotation of the rotary attachment 9, the open biopsy trap 1 is rotated, whereby a sample of the lung parenchyma is taken.
- the biopsy trap 1 By releasing the proximal-distal pressure, the biopsy trap 1 closes, while the lung parenchyma sample remains inside the biopsy trap due to its porosity.
- the invention is repeatedly industrially applicable in the field of medicine, in particular diagnostics.
Abstract
The lung parenchyma sampling device is formed at the distal end by a biopsy trap (1) and at the proximal end by a control device (2) of the biopsy trap (1) which are interconnected by a catheter (8) comprising a rod (5). The biopsy trap (1) consists of at least three flexible flat blades (3) located around the central part, formed by the catheter (8) provided with the rod (5) and connected to a rotating extension (9) of the catheter (8) located on the control device (2). The blades (3) are firmly connected to the central part at the distal end of the biopsy trap (1) by a soft fixation element (6a), and the proximal end of the biopsy trap (1) is formed by a proximal-moving anchor (7) of blades (3) provided with a soft fixing element (6b).
Description
Description
Title of Invention: Equipment for the collection of lung tissue in the endoscopic examination of the lungs
Technical Field
[0001] The present invention relates to a device for collecting lung tissue while minimizing the risk of bleeding or rupture of the lung during sampling of a lung parenchyma.
Background Art
[0002] Endoscopic lung examinations are now part of common medical practice. The
reasons for the examination are various, endoscopic examination of the lungs is performed for both diagnostic and therapeutic reasons.
[0003] For diagnostic purposes, it is necessary to take samples from the airways.
[0004] Several techniques for sampling the airways and their surroundings are currently known. These include endobronchial aspiration, perbronchial puncture, brush biopsy, bronchalveolar lavage, endobronchial excision, transbronchial lung biopsy, and trans- bronchial cryobiopsy.
[0005] Two of these methods are used for lung parenchyma sampling, namely trans
bronchial biopsy, where sampling from the peripheral part of the bronchial tree is performed using biopsy forceps (samples of the lung parenchyma are also obtained during the examination), as well as transbronchial lung cryobiopsy, which is a method for obtaining larger samples of the lung parenchyma using a special freezing probe (cryoprobe).
[0006] In both of the above cases, it is a procedure in which a biopsy device is inserted into the periphery of the lungs to remove adjacent tissue. This can be done without control or with the help of ski-optical control. Both of the above techniques have common un desirable side effects, especially pneumothorax, which occurs when a biopsy device gets too close to the lung border and causes a rupture in the gutter. This risk is 1-5% for transbronchial biopsies and up to 50% for transbronchial pulmonary cryobiopsies. The second serious side effect is bleeding, which is usually not severe with a trans bronchial biopsy, but can be severe with a transbronchial pulmonary cryobiopsy due to the size of the sample taken. Bleeding occurs in up to 40% of patients undergoing lung parenchyma biopsy.
[0007] It is therefore desirable to find a solution that would eliminate the risks associated with pulmonary parenchymal sampling.
[0008] From the state of the art, solutions are known which consist of pliers which are
closed in the boot state so as to form a rounded tip. Examples are US2018353162, CN108969026, US2018280004, WO2018152626, WO 2014/186319 or
US2018177496. The disadvantage of these solutions is that the forceps must be opened and brought closer to the sampling point before the actual sampling. Because the in dividual arms of these forceps are formed to form spikes at their distal end, there is still a high risk of tissue injury and pneumothorax or bleeding.
[0009] The object of the invention is to provide a device for sampling the lung parenchyma which would substantially reduce the risks described.
Summary of Invention
[0010] This task is solved by a lung parenchyma sampling device having a biopsy trap at the distal end and a biopsy trap control device at the proximal end. The biopsy trap is formed of at least three flexible flat blades located around a central portion formed by a catheter and provided with a rod for actuating the biopsy trap. The blades are firmly connected to the catheter at the distal end of the biopsy trap by means of a soft fixation element, the length of which is 1-5 mm, and serves as protection against pneu mothorax. The proximal end of the biopsy trap is formed by a proximal-distally movable anchor of the blade provided with a soft fixation element. The biopsy trap and the biopsy trap control device are connected by a catheter comprising a rod for con trolling the proximo-distal movement of the blade and a rotating catheter extension for controlling the rotation of the biopsy trap.
[0011] In a preferred embodiment, the blades are made of austenitic or martensitic stainless steel of surgical grade or of a compound of nickel and titanium of surgical grade.
[0012] In a preferred embodiment, the fixing elements are made of a photopolymerically cured medical resin.
Brief Description of Drawings
Fig·!
[0013] [Fig.l] illustrates a view of the biopsy trap in the open state,
Fig.2
[0014] [Fig.2] illustrates a closed biopsy trap located in the working channel of the bron choscope,
Fig.3
[0015] [Fig.3] illustrates the whole device with a closed biotic trap,
Fig.4
[0016] [Fig.4] illustrates the whole device with an open biotic trap,
Examples
[0017] Example 1
[0018] The lung parenchyma sampling device has a biopsy trap 1 at the distal end and a biopsy trap 1 control device 2 at the proximal end. The biopsy trap 1 is formed of four flexible flat blades 3 placed around a central part formed by a catheter 8 provided with
a rod 5 for actuating the biopsy trap L The blades 3 are firmly connected to the catheter 8 at the distal end of the biopsy trap 1 by means of a soft fixation element 6a, the length of which is 1-5 mm and serves as protection against pneumothorax. The proximal end of the biopsy trap 1 is formed by a proximo-distally movable anchor 7 of the blade 3 provided with a soft fixation element 6b. The biopsy trap 1 and the control device 2 of the biopsy trap 1 are connected by a catheter 8 comprising a rod 5 for con trolling the proximo-distal movement of the blade 3 and a rotating attachment 9 of the catheter 8 for controlling the rotation of the biopsy trap 1. The blades 3 are made of austenitic steel in surgical quality. The fixing elements 6a, 6b are made of a resin usable in healthcare cured by photopolymerization. The lung parenchyma sampling device is inserted into the working channel of the bronchoscope 10, through which the biopsy trap 1 is introduced at the sampling site. By the action of the proximo-distal pressure by means of the rod 5, the blade 3 is compressed to a predefined diameter, whereby the biopsy trap 1 is opened by creating gaps between the individual blades 3. By the action of the rotational force caused by the rotation of the rotary attachment 9, the open biopsy trap 1 is rotated, whereby a sample of the lung parenchyma is taken. By releasing the proximal-distal pressure, the biopsy trap 1 closes, while the lung parenchyma sample remains inside the biopsy trap due to its porosity.
[0019] Example 2
[0020] The lung parenchyma sampling device has a biopsy trap 1 at the distal end and a biopsy trap 1 control device 2 at the proximal end. The biopsy trap 1 is formed of six flexible flat blades 3 placed around a central part formed by a catheter 8 provided with a rod 5 for actuating the biopsy trap 1. The blades 3 are firmly connected to the catheter 8 at the distal end of the biopsy trap 1 by means of a soft fixation element 6a, the length of which is 1-5 mm and serves as protection against pneumothorax. The proximal end of the biopsy trap 1 is formed by a proximo-distally movable anchor 7 of the blade 3 provided with a soft fixation element 6b. The biopsy trap 1 and the control device 2 of the biopsy trap 1 are connected by a catheter 8 comprising a rod 5 for con trolling the proximo-distal movement of the blade 3 and a rotating attachment 9 of the catheter 8 for controlling the rotation of the biopsy trap 1. The blades 3 are made of a compound of nickel and titanium in surgical quality. The fixing elements 6a, 6b are made of a resin usable in healthcare cured by photopolymerization. The lung parenchyma sampling device is inserted into the working channel of the bronchoscope 10, through which the biopsy trap 1 is introduced at the sampling site. By the action of the proximo-distal pressure by means of the rod 5, the blade 3 is compressed to a predefined diameter, whereby the biopsy trap 1 is opened by creating gaps between the individual blades 3. By the action of the rotational force caused by the rotation of the rotary attachment 9, the open biopsy trap 1 is rotated, whereby a sample of the lung
parenchyma is taken. By releasing the proximal-distal pressure, the biopsy trap 1 closes, while the lung parenchyma sample remains inside the biopsy trap due to its porosity.
Industrial Applicability
[0021] The invention is repeatedly industrially applicable in the field of medicine, in particular diagnostics.
Claims
[Claim 1] A lung parenchyma sampling device formed at the distal end by a
biopsy trap 1 and at the proximal end by a control device 2 of a biopsy trap 1 interconnected by a catheter 8 comprising a rod 5, characterized in that the biopsy trap 1 is formed by at least three flexible flat blades 3 located around a central part formed by a catheter 8 provided with a rod 5 and connected to a rotating extension 9 of the catheter 8 located on the control device 2, the blades 3 being firmly connected to the central part 4 at the distal end of the biopsy trap 1 by a soft fixation element 6a and the proximal end of the biopsy trap 1 being formed a proximo- distally movable anchor 7 of the blade 3 provided with a soft fixing element 6b.
[Claim 2] The according to claim 1, characterized in that the blades 3 are made of austenitic or martensitic stainless steel in surgical grade or of a compound of nickel and titanium in surgical grade.
[Claim 3] The according to claim 1 or 2, characterized in that the fixing elements
6a, 6b are made of a resin usable in healthcare cured by photopoly merization.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20809163.7A EP3965661A4 (en) | 2019-05-20 | 2020-05-20 | Equipment for the collection of lung tissue in the endoscopic examination of the lungs |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CZPV2019-310 | 2019-05-20 | ||
CZ2019-310A CZ2019310A3 (en) | 2019-05-20 | 2019-05-20 | Equipment for collecting lung tissue in an endoscopic lung examination |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2020233730A1 true WO2020233730A1 (en) | 2020-11-26 |
Family
ID=73458382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CZ2020/050031 WO2020233730A1 (en) | 2019-05-20 | 2020-05-20 | Equipment for the collection of lung tissue in the endoscopic examination of the lungs |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3965661A4 (en) |
CZ (1) | CZ2019310A3 (en) |
WO (1) | WO2020233730A1 (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5282484A (en) * | 1989-08-18 | 1994-02-01 | Endovascular Instruments, Inc. | Method for performing a partial atherectomy |
WO1999004704A2 (en) * | 1997-07-24 | 1999-02-04 | Mcguckin James F Jr | Breast surgery method and apparatus |
US6152932A (en) * | 1996-03-25 | 2000-11-28 | Safe Conduct Ab | Device for extraction of tissue |
US8668654B1 (en) * | 2013-03-13 | 2014-03-11 | Sanovas, Inc. | Cytological brushing system |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090124927A1 (en) * | 2007-11-13 | 2009-05-14 | Chest Innovations, Inc. | Endoscopic system for lung biopsy and biopsy method of insufflating gas to collapse a lung |
JP5809621B2 (en) * | 2009-05-18 | 2015-11-11 | ヌームアールエックス・インコーポレーテッド | Implants for treating a patient's lungs |
EP2683309B1 (en) * | 2011-03-09 | 2021-04-21 | Neuravi Limited | A clot retrieval device for removing occlusive clot from a blood vessel |
-
2019
- 2019-05-20 CZ CZ2019-310A patent/CZ2019310A3/en not_active IP Right Cessation
-
2020
- 2020-05-20 EP EP20809163.7A patent/EP3965661A4/en not_active Withdrawn
- 2020-05-20 WO PCT/CZ2020/050031 patent/WO2020233730A1/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5282484A (en) * | 1989-08-18 | 1994-02-01 | Endovascular Instruments, Inc. | Method for performing a partial atherectomy |
US6152932A (en) * | 1996-03-25 | 2000-11-28 | Safe Conduct Ab | Device for extraction of tissue |
WO1999004704A2 (en) * | 1997-07-24 | 1999-02-04 | Mcguckin James F Jr | Breast surgery method and apparatus |
US8668654B1 (en) * | 2013-03-13 | 2014-03-11 | Sanovas, Inc. | Cytological brushing system |
Non-Patent Citations (1)
Title |
---|
See also references of EP3965661A4 * |
Also Published As
Publication number | Publication date |
---|---|
CZ308587B6 (en) | 2020-12-16 |
CZ2019310A3 (en) | 2020-12-16 |
EP3965661A1 (en) | 2022-03-16 |
EP3965661A4 (en) | 2023-01-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10792022B2 (en) | Tissue sampling devices, systems and methods | |
EP2303153B1 (en) | Biopsy device | |
CN110141181B (en) | Apparatus, system, and method for obtaining tissue samples using biopsy tools | |
US8226575B2 (en) | Biopsy needle assemblies | |
JP6017414B2 (en) | Endoscopic ultrasound guided biopsy needle | |
JP2012517290A (en) | Apparatus and method for accessing a body part | |
US20180116645A1 (en) | Stylet and Needle Combinations Used to Collect Tissue Samples During Endoscopic Procedures | |
US20160000415A1 (en) | Multiple-tissue fna sampling | |
US20220346761A1 (en) | Biopsy device | |
WO2020233730A1 (en) | Equipment for the collection of lung tissue in the endoscopic examination of the lungs | |
JP6471904B2 (en) | Tissue and / or cell sampling device | |
CZ34135U1 (en) | Equipment for collecting lung tissue in an endoscopic examination of the lungs | |
US20160095584A1 (en) | Endoscopic needle with rotary jaw for lateral acquisition | |
CN108697412A (en) | System and method for improved tissue sampling | |
EP3174469B1 (en) | Scooper core needle | |
US20230132190A1 (en) | Flexible scope with improved suction | |
US20230125835A1 (en) | Scope with controllable energy tip | |
JP2018530409A (en) | Biological tissue sampling device | |
IES85915Y1 (en) | Endoscopic ultrasound-guided biopsy needle | |
IE20110141U1 (en) | Endoscopic ultrasound-guided biopsy needle |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 20809163 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
ENP | Entry into the national phase |
Ref document number: 2020809163 Country of ref document: EP Effective date: 20211209 |