WO2020231371A1

WO2020231371A1 - Vein valve washing catheter

Info

Publication number: WO2020231371A1
Application number: PCT/TR2020/050405
Authority: WO
Inventors: Sonay OGUZ
Original assignee: Canakkale Onsekiz Mart Universitesi Rektorlugu
Priority date: 2019-05-16
Filing date: 2020-05-08
Publication date: 2020-11-19
Also published as: TR201907422A2

Abstract

The invention relates to a vein valve washing catheter that is developed to clean the clots remaining between the venous blood vessel valves and the blood vessel wall. By means of the catheter of the invention, it is aimed to eliminate the diseases and vascular dysfunctions that may occur due to clots between the valves in the vein and the vessel wall.

Description

VEIN VALVE WASHING CATHETER

Technical Field

The invention relates to a vein valve washing catheter that is developed to clean the clots remaining between the venous blood vessel valves and the blood vessel wall.

Prior Art

Although the clots occurring in the vein today are tried to be cleaned by both medication and the use of a catheter, the clot substantially remains in the blind area between the valve and the wall and this clot causes vascular dysfunction.

Clot formation in the veins is defined as deep vein thrombosis (DVT). Various treatment methods are available in the art to treat this disease based on the principle of breaking down and aspirating (withdrawing by suction) the clot by a catheter together with the blood thinning agent and clot dissolving agents.

Today, “pharmacomechanical - mechanical thrombectomy / aspiration” methods are the methods used in the treatment of deep vein thrombosis (DVT). As an example, many “pharmacomechanical - mechanical thrombectomy / aspiration” systems such as invamed- mantis, mantis xp, dovi. aspirex, angiovac, angiojet are available in the art.

The Turkish patent document numbered TR201705510 in the known state of the art discloses a bronchial dilator balloon catheter having at least two catheter balloons that can be inflated separately or together to provide dilatation and at least a bilateral resection and hemoptysis control, of which, at least one has a distal structure of the bronchial tree and at least one has the form and diameter suitable for the proximal structure of the bronchial tree; at least three catheter ports, wherein at least one of them provides flush injection application, at least the other one provides an aspiration application and imaging, and at least the other one enables the catheter balloons to inflate; a washing apparatus that allows the imaging optics that are closed after bleeding to be cleaned and to recapture images and a catheter shaft that serves as the main body of the catheter and forms the passage channel of the aspiration and imaging devices with the relevant catheter port.

The U.S. patent document numbered US5489278 discloses a catheter that removes blockages and clot formation within the vessel by applying positive or negative pressure to the fluid in the vessel lumen.

The U.S. patent document numbered US2017049470 discloses a catheter system that comprises a flexible, bending resistant tube, a vacuum source attached to the proximal end of the catheter lumen and the aspiration lumen.

The U.S. patent document numbered US5125893 discloses a washing catheter having a vacuuming feature and also comprising a lumen through which the washing liquid passes. The proximal end of the lumen contains a tube connected by a fitting suitable for the source of the washing liquid.

When the methods available in the art were examined, it was observed that it was necessary to develop a catheter that could be used to clean the clots between the valves in the vein and the vessel wall.

Object of the Invention

The object of the present invention is to realize a catheter that can be used to clean the clots between the valves in the vein and the vessel wall.

Another object of the present invention is to realize a catheter developed to eliminate the diseases and vascular dysfunctions that may occur due to clots between the valves in the vein and the vessel wall.

Detailed Description of the Invention The vein valve washing catheter developed to fulfill the objects of the invention is shown in the figures attached.

Figure 1: is the side view of the catheter subject to the invention in the closed state of the collapsible tip.

Figure 2: is the side view of the catheter subject to the invention in the open state of the collapsible tip.

Figure 3: is the front sectional view of the collapsible tip of the catheter subject to the invention when it is closed, half open and open.

Figure 4: is the rear sectional view of the collapsible tip of the catheter subject to the invention when it is closed, half open and open.

Figure 5: is the side view of the collapsible tip of the catheter subject to the invention when it is closed, half open and open.

Figure 6: is the side view of the outer catheter body of the catheter subject to the invention.

Figure 7: is the side view of the inner catheter body of the catheter subject to the invention.

Figure 8: is the view of the collapsible tip in the catheter subject to the invention when it is in the outer catheter body.

Figure 9: is the side view of the collapsible tip when it is open, when the catheter subject to the invention is used in antegrade form.

Figure 10: is the side view of the collapsible tip when it is closed, when the catheter subject to the invention is used in antegrade form.

Figure 11: is the view of the catheter which is the subject of the invention when it is inserted in the vein while the collapsible tip is closed. Figure 12: is the view of the collapsible tip of the catheter subject to the invention when it is opened in the vein.

Figure 13: is the view of the catheter subject to the invention when the washing liquid is started to be sprayed, while it is in the vein.

Figure 14: is the view of the catheter subject to the invention when it is rotated around itself while being pulled back after starting the washing process.

The parts in the figures have each been numbered and their equivalents are given below.

1. Outer catheter body

2. Inner catheter body

3. Collapsible tip

4. End slot

5. Movable part

6. Liquid inlet part

7. Guide wire through holes

The invention is a vein valve washing catheter, comprising; an outer catheter body (1) in the form of a hollow tube,

an inner catheter body (2) positioned so as to be inserted into the outer catheter body

(1),

a collapsible tip (3) located at the tip of the inner catheter body (2),

an end slot (4) located on the outer catheter body (1) which is positioned to include the collapsible tip (3),

a movable part (5) located on the outer catheter body (1) that enables the end slot (4) to move back and forth on the collapsible tip (3),

a liquid inlet part (6) located at the head of the inner catheter body (2),

guide wire through holes (7) provided on the end slot (4) The outer catheter body (1) has a flexible, non-folding structure that allows access within the vein, and allows the passage of the inner catheter body (2) through it. The movement of the end slot (4) on the outer catheter body (1) is provided with the movable part (5). (Figure 6)

The guide wire, which passes through the guide wire through holes (7), allows the catheter to be delivered to the desired area without being snagged by the vein valves. The liquid sent over the liquid inlet part (6) is sprayed by fringing out like a fan, by means of the multi -point holes on the collapsible tip (3). In this way, pressure is distributed and damage to the vein is prevented. (Figure 13)

When the catheter of the invention is inserted into the vein, firstly, the collapsible tip (3) is inserted in the vein with the help of a guide wire, such that it is closed. The valves that do not allow the reverse passage in the vein are surpassed in this way and the catheter is placed in the vein in the appropriate position. (Figure 11)

Then, the collapsible tip (3) in the catheter is opened and positioned to be between the valves and the vessel wall. Washing liquid with the desired quality is sent to the catheter via the liquid inlet part (6) of the catheter. The transferred liquid is sprayed from the collapsible end (3) part through the vein valve to the vessel wall joining area. With the created pressure effect, the valve closes in the same way as in normal circulation and flows from the middle of the vein to the sprayed liquid and towards the clots that have broken away. At this point, particles are captured according to the pharmaco -mechanical method that is used. (Aspiration, cava filter etc.) (Figure 12)

While the catheter is being pulled back after starting the washing process, all the clots are tried to be removed by being rotated around itself. With the pressure effect of the liquid supplied, in the region located at the end of the valves, the valves close and they create a backward flow in the vein, all of the clots are tried to be removed with this current power. If desired, the process can be made more effective by adding strong clot dissolving agents to the washing liquid. However, these agents should be used with caution as they have a potential to increase bleeding. (Figure 14) All these procedures are carried out in accordance with the basic angiography rules. In the angiography unit, images can be taken by giving contrast, and if necessary, complete cleaning can be achieved by repeating the procedure sequentially. The vein access zone may vary according to the pharmaco-mechanical method accompanied.

The catheter of the invention is for cleaning the pieces of clot between the valve and the vessel wall after another pharmaco-mechanical or mechanical main clot removal procedure. While performing this process, the clot pieces that are attached to the wall lumen can be removed.

Moreover, the catheter of the invention can be designed in systems that are directed as antegrade (from lower part to top, i.e. from the legs to the trunk) and retrograde (from top to bottom, i.e. from the trunk to the legs). In this design, only the direction of the collapsible tip (3) to be used will be changed (Figure 9, Figure 10).

By means of the catheter according to the invention, the area between the vessel wall and the valve can be reached easily and the clot can be cleaned completely. High success in treatment is achieved by complete elimination of the clot. The catheter of the invention can be used in any of the pharmaco-mechanical treatment methods used in the treatment of deep vein thrombosis (DVT) to completely remove the clot. Pharmaco-mechanical methods can be in retrograde (from above; from the upper part of the trunk down to the leg) and antegrade (from the lower leg to the upper part) form. Therefore, the catheter according to the invention can be designed to be suitable for such approaches.

Claims

1. A vein valve washing catheter comprising,

- an outer catheter body (1) in the form of a hollow tube,

- an inner catheter body (2) positioned so as to be inserted into the outer catheter body (1), characterized by comprising;

- a collapsible tip (3) located at the tip of the inner catheter body (2),

- an end slot (4) located on the outer catheter body (1) which is positioned to include the collapsible tip (3).

2. A catheter according to Claim 1, characterized by comprising a movable part (5) located on the outer catheter body (1) that enables the end slot (4) to move back and forth on the collapsible tip (3).

3. A catheter according to Claim 2, characterized by comprising a liquid inlet part (6) located at the head of the inner catheter body (2).

4. A catheter according to Claim 3, characterized by comprising guide wire through- holes (7) provided on the end slot (4).