WO2020215806A1 - Video acquisition system for narrow cavitary space based on microprobe structure - Google Patents

Video acquisition system for narrow cavitary space based on microprobe structure Download PDF

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WO2020215806A1
WO2020215806A1 PCT/CN2020/000062 CN2020000062W WO2020215806A1 WO 2020215806 A1 WO2020215806 A1 WO 2020215806A1 CN 2020000062 W CN2020000062 W CN 2020000062W WO 2020215806 A1 WO2020215806 A1 WO 2020215806A1
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microprobe
tissue
tissues
lesions
video acquisition
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PCT/CN2020/000062
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French (fr)
Chinese (zh)
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王玉峰
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天津御锦人工智能医疗科技有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/31Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes, colonoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/04Endoscopic instruments
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/04Endoscopic instruments
    • A61B2010/045Needles

Abstract

A video acquisition system for a narrow cavitary space based on a microprobe structure, comprising an intelligent computer aided diagnosis system and a microprobe (104). The intelligent computer aided diagnosis system trains a large number of pictures of different lesions using a deep learning technique, and can complete auxiliary diagnosis of different common lesions in the colonoscopy process. The microprobe (104) is provided at the tail end of a clamp channel (103) for taking samples from tissues. When the intelligent computer aided diagnosis system determines that some of the tissues taken out are pathological tissues, the microprobe (104) is retracted from the clamp channel (103) and carries the pathological tissues out of a colonoscope (102) duct from the clamp channel (103). When it is determined that the some of the tissues taken out are normal intestinal tissues or intestinal debris, the microprobe (104) discharges the tissues and is not retracted. The video acquisition system can reduce the probability of missed detection of lesions.

Description

一种基于微探针结构的腔道窄小空间视频采集系统Video acquisition system based on micro-probe structure in narrow space of cavity 技术领域Technical field
本发明涉及基于微探针的病变检测技术领域,特别地,涉及一种基于微探针结构的腔道窄小空间视频采集系统。The present invention relates to the technical field of lesion detection based on microprobes, in particular to a video acquisition system based on a microprobe structure in a narrow space of a cavity.
背景技术Background technique
结肠息肉是消化系统的常见疾病,很多患者因为腹痛、便血等症状,做肠镜检查,内镜下诊断为结肠息肉。结肠癌是我国常见消化系肿瘤之一,随着人们生活水平的不断提高,结肠癌发病率在不断增加。电子肠镜是目前结肠息肉最主要的检查方法,同时也是结肠息肉内镜下治疗的主要手段。镜下息肉的数目、直径、生长方式、部位和息肉病理相关,检查时着重观察有利于结肠息肉的诊断和治疗。Colon polyps are a common disease of the digestive system. Many patients undergo colonoscopy due to symptoms such as abdominal pain and blood in the stool, and are diagnosed as colon polyps under endoscopy. Colon cancer is one of the common digestive system tumors in my country. With the continuous improvement of people's living standards, the incidence of colon cancer is increasing. Electronic enteroscopy is currently the most important inspection method for colon polyps, and it is also the main method of endoscopic treatment of colon polyps. The number, diameter, growth pattern, location of polyps under the microscope are related to the pathology of polyps, and the focus on observation during the examination is beneficial to the diagnosis and treatment of colon polyps.
在结肠镜检查过程中,有关息肉、肿瘤等病变的主要病理分析方法是使用手术钳去除后去除肠道然后送活检,进一步分析肿物的病理性质,从而可以判断患者的患病严重程度以及风险。在检查过程中存在腔道窄小以及难以展开的皱襞等不易于观察的部位,目前的结肠镜检查手术中存在漏诊情况,其中有一部分原因正是由于难以针对这些部位观察和取样分析。In the process of colonoscopy, the main pathological analysis method for polyps, tumors and other lesions is to use surgical forceps to remove the intestine and then send a biopsy to further analyze the pathological nature of the tumor, so as to determine the severity and risk of the patient . During the inspection, there are parts that are not easy to observe, such as narrow cavities and difficult to unfold folds. The current colonoscopy surgery has missed diagnosis. Part of the reason is that it is difficult to observe and sample and analyze these parts.
发明内容Summary of the invention
针对上述现有技术中存在的技术问题,本发明的目的是提供一种基于微探针结构的腔道窄小空间视频采集系统。In view of the above-mentioned technical problems in the prior art, the purpose of the present invention is to provide a micro-probe structure-based video acquisition system in a narrow space with a cavity.
为实现本发明的目的,本发明提供了一种基于微探针结构的腔道窄小空间视频采集系统,包括:In order to achieve the objective of the present invention, the present invention provides a micro-probe structure-based video acquisition system in a narrow space of a cavity, including:
智能计算机辅助诊断(CAD)系统和微探针,Intelligent Computer Aided Diagnosis (CAD) system and micro probes,
所述CAD系统使用深度学习技术训练大量各类病变的图片,通过所述CAD系统能够在进行结肠镜手术过程中完成各类常见病变的辅助诊断;The CAD system uses deep learning technology to train a large number of pictures of various lesions, and the CAD system can complete the auxiliary diagnosis of various common lesions during the colonoscopy operation;
所述微探针设置在钳道末端,微探针用于从组织中取样;The microprobe is arranged at the end of the clamp channel, and the microprobe is used to sample from the tissue;
所述CAD系统用于,通过图像识别技术,识别取出部分组织是否有发生病变的可能,当CAD系统判定取出的部分组织为病变组织时,探针收回钳道,从钳道中将病变组织携带出结肠镜管道;当CAD系统判定取出的部分组织为正常肠道组织或者肠道内杂物时,探针将其排出,不进行收回。The CAD system is used to identify whether the removed part of the tissue is likely to have lesions through image recognition technology. When the CAD system determines that the removed part of the tissue is a diseased tissue, the probe retracts the clamp channel and carries the diseased tissue out of the clamp channel Colonoscopy pipeline; when the CAD system determines that the removed part of the tissue is normal intestinal tissue or intestinal debris, the probe will expel it and not retract it.
与现有技术相比,本发明的有益效果为,本发明提出了一种基于微探针结构的腔道窄小空间视频采集系统,能够在结肠镜手术过程中使用微探针从腔道窄小空间取出部分组织,从而可以进一步判断分析视野内相应组织是否存在病变,从而更加快捷方便地判断出患者的患病情况,降低病变的漏检概率。对于可能患病的组织能够通过结肠镜钳道使用微探针取出做进一步检查分析,对于正常组织则排在肠腔中不做进一步检查。Compared with the prior art, the beneficial effect of the present invention is that the present invention proposes a micro-probe structure-based video acquisition system for narrow cavity space, which can use the micro-probe to remove the narrow space from the cavity during colonoscopy. Part of the tissue is taken out in a small space, so that it can be further judged whether there is a disease in the corresponding tissue in the analysis field, so as to determine the patient's disease more quickly and conveniently, and reduce the probability of missed detection of the disease. The tissues that may be diseased can be removed by the colonoscopy forceps using micro-probes for further examination and analysis, and normal tissues are placed in the intestinal lumen without further examination.
附图说明Description of the drawings
图1为本申请基于微探针结构的腔道窄小空间视频采集系统结构示意图。其中:101表示人体肠道,102表示手术过程中的结肠镜,103表示结肠镜中的钳道,104表示微探针。FIG. 1 is a schematic diagram of the structure of a video acquisition system in a narrow space of a cavity based on a microprobe structure of the present application. Among them: 101 represents the human intestine, 102 represents the colonoscope during surgery, 103 represents the clamp channel in the colonoscope, and 104 represents the microprobe.
图2为本申请系统操作流程示意图。Figure 2 is a schematic diagram of the operation flow of the application system.
具体实施方式Detailed ways
以下结合附图和具体实施例对本发明作进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。The present invention will be further described in detail below in conjunction with the drawings and specific embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, but not to limit the present invention.
应当说明的是,本申请中所述的“连接”和用于表达“连接”的词语,如“相连接”、“相连”等,既包括某一部件与另一部件直接连接,也包括某一部件通过其他部件与另一部件相连接。It should be noted that the "connected" and the words used to express "connected" in this application, such as "connected", "connected", etc., include not only the direct connection of a component with another component, but also One component is connected to another component through other components.
需要注意的是,这里所使用的术语仅是为了描述具体实施方式,而非意图限制根据本申请的示例性实施方式。如在这里所使用的,除非上下文另外明确指出,否则单数形式也意图包括复数形式,此外,还应当理解的是,当在本说明书中使用属于“包含”和/或“包括”时,其指明存在特征、步骤、操作、部件或者模块、组件和/或它们的组合。It should be noted that the terms used here are only for describing specific embodiments, and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly dictates otherwise, the singular form is also intended to include the plural form. In addition, it should also be understood that when “including” and/or “including” are used in this specification, it indicates There are features, steps, operations, components or modules, components and/or combinations thereof.
需要说明的是,本申请的说明书和权利要求书及上述附图中的术语“第一”、“第二”等是用于区别类似的对象,而不必用于描述特定的顺序或先后次序。应该理解这样使用的数据在适当情况下可以互换,以便这里描述的本申请的实施方式例如能够以除了在这里图示或描述的那些以外的顺序实施。此外,术语“包括”和“具有”以及他们的任何变形,意图在于覆盖不排他的包含,例如,包含了一系列步骤或单元的过程、方法、系统、产品或设备不必限于清楚地列出的那些步骤或单元,而是可包括没有清楚地列出的或对于这些过程、方法、产品或设备固有的其它步骤或单元。It should be noted that the terms "first" and "second" in the description and claims of the application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific sequence or sequence. It should be understood that the data used in this way can be interchanged under appropriate circumstances, so that the embodiments of the present application described herein can be implemented in a sequence other than those illustrated or described herein, for example. In addition, the terms "including" and "having" and any variations of them are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to the clearly listed Those steps or units may include other steps or units that are not clearly listed or are inherent to these processes, methods, products, or equipment.
为了便于描述,在这里可以使用空间相对术语,如“在......之上”、“在......上方”、“在......上表面”、“上面的”等,用来描述如在图中所示的一个部件或者模块或特征与其他部件或者模块或特征的空间位置关系。应当理解的是,空间相对术语旨在包含除了部件或者模块在图中所描述的方位之外的在使用或操作中的不同方位。例如,如果附图中的部件或者模块被倒置,则描述为“在其他部件或者模块或构造上方”或“在其他部件或者模块或构造之上”的部件或者模块之后将被定位为“在其他部件或者模块或构造下方”或“在其他部件或者模块或构造之下”。因而,示例性术语“在......上方”可以包括“在......上方”和“在......下方”两种方位。该部件或者模块也可以其他不同方式定位(旋转90度或处于其他方位),并且对这里所使用的空间相对描述作出相应解释。For ease of description, spatial relative terms can be used here, such as "above", "above", "above the surface", "above "的", etc., are used to describe the spatial position relationship between a component or module or feature and other components or modules or features as shown in the figure. It should be understood that the spatially relative terms are intended to encompass different orientations in use or operation other than the orientations of components or modules described in the figures. For example, if a component or module in the drawing is inverted, then a component or module described as "above other components or modules or structures" or "above other components or modules or structures" will then be positioned as "above other components or modules or structures". A component or module or structure" or "below another component or module or structure". Thus, the exemplary term "above" can include both orientations "above" and "below". The component or module can also be positioned in other different ways (rotated by 90 degrees or in other orientations), and the relative description of the space used here shall be explained accordingly.
需要说明的是,在不冲突的情况下,本申请中的实施例及实施例中的特征可以相互组合。It should be noted that the embodiments in this application and the features in the embodiments can be combined with each other if there is no conflict.
为了针对肠镜视频进行实时息肉、肿瘤等常见易引起癌症的肠道病变检测分析处理,本发明提出了一种基于微探针结构的腔道窄小空间视频采集系统,用于常见肠道病变的分析取样,有效辅助医生进行结肠镜手术检查,提高检查效率。In order to perform real-time detection and analysis of intestinal lesions such as polyps, tumors and other common cancer-prone intestinal lesions based on enteroscopy videos, the present invention proposes a micro-probe structure-based video acquisition system for narrow spaces in the lumen, which is used for common intestinal lesions. The analysis and sampling can effectively assist doctors in performing colonoscopy and improve the efficiency of inspection.
如图1和图2所示,本发明提供了一种基于微探针结构的腔道窄小空间视频采集系统,包括:As shown in Figure 1 and Figure 2, the present invention provides a micro-probe structure-based video acquisition system in a narrow space with a cavity, including:
智能计算机辅助诊断(CAD)系统和微探针,Intelligent Computer Aided Diagnosis (CAD) system and micro probes,
所述CAD系统使用深度学习技术训练大量各类病变的图片,通过所述CAD系统能够在进行结肠镜手术过程中完成各类常见病变的辅助诊断;The CAD system uses deep learning technology to train a large number of pictures of various lesions, and the CAD system can complete the auxiliary diagnosis of various common lesions during the colonoscopy operation;
所述微探针设置在钳道末端,微探针用于从组织中取样;The microprobe is arranged at the end of the clamp channel, and the microprobe is used to sample from the tissue;
所述CAD系统用于,通过图像识别技术,识别取出部分组织是否有发生病变的可能,当CAD系统判定取出的部分组织为病变组织时,探针收回钳道,从钳道中将病变组织携带出结肠镜管道;当CAD系统判定取出的部分组织为正常肠道组织或者肠道内杂物时,探针将其排出,不进行收回。The CAD system is used to identify whether the removed part of the tissue is likely to have lesions through image recognition technology. When the CAD system determines that the removed part of the tissue is a diseased tissue, the probe retracts the clamp channel and carries the diseased tissue out of the clamp channel Colonoscopy pipeline; when the CAD system determines that the removed part of the tissue is normal intestinal tissue or intestinal debris, the probe will expel it and not retract it.
本系统的操作步骤如下:The operation steps of this system are as follows:
步骤201,在检查过程中遇到腔道窄小以及难以展开的皱襞等不易于观察的部位时采取下一步操作;Step 201: Take the next step when encountering parts that are not easy to observe, such as narrow cavities and hard-to-open folds, during the inspection;
步骤202,使用微探针取样,将微探针从钳道中伸出并且在窄小部位进行取样; Step 202, use the microprobe to sample, extend the microprobe from the clamp channel and sample at a narrow part;
步骤203,使用智能辅助诊断CAD系统,利用图像识别技术,识别取出部分组织是否有发生病变的可能;Step 203: Use an intelligent assisted diagnosis CAD system and use image recognition technology to identify whether the removed part of the tissue is likely to cause disease;
步骤204,当CAD系统判定取出的部分组织为病变组织时,探针收回钳道,从钳道中将病变组织携带出结肠镜管道,将使用微探针携带取出的肠道组织送活检进行进一步病理分析;Step 204: When the CAD system determines that the removed part of the tissue is a diseased tissue, the probe retracts the clamp channel, carries the diseased tissue out of the colonoscopy tube from the clamp channel, and sends the intestinal tissue removed using the microprobe to the biopsy for further pathology analysis;
步骤205,当CAD系统判定取出的部分组织为正常肠道组织或者肠道内杂物时,探针将其排出,不进行收回。In step 205, when the CAD system determines that the part of the tissue taken out is normal intestinal tissue or intestinal debris, the probe will expel it without taking it back.
以上所述仅是本发明的优选实施方式,应当指出的是,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以做出若干改进和润饰,这些改进和润饰也应视为本发明的保护范围。The above are only the preferred embodiments of the present invention. It should be pointed out that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and modifications can be made. These improvements and Retouching should also be regarded as the protection scope of the present invention.

Claims (1)

  1. 一种基于微探针结构的腔道窄小空间视频采集系统,其特征在于,包括:智能计算机辅助诊断(CAD)系统和微探针,A video acquisition system based on a micro-probe structure in a narrow space of a cavity is characterized in that it includes an intelligent computer-aided diagnosis (CAD) system and a micro-probe,
    所述CAD系统使用深度学习技术训练大量各类病变的图片,通过所述CAD系统能够在进行结肠镜手术过程中完成各类常见病变的辅助诊断;The CAD system uses deep learning technology to train a large number of pictures of various lesions, and the CAD system can complete the auxiliary diagnosis of various common lesions during the colonoscopy operation;
    所述微探针设置在钳道末端,微探针用于从组织中取样;The microprobe is arranged at the end of the clamp channel, and the microprobe is used to sample from the tissue;
    所述CAD系统用于,通过图像识别技术,识别取出部分组织是否有发生病变的可能,当CAD系统判定取出的部分组织为病变组织时,探针收回钳道,从钳道中将病变组织携带出结肠镜管道;当CAD系统判定取出的部分组织为正常肠道组织或者肠道内杂物时,探针将其排出,不进行收回。The CAD system is used to identify whether the removed part of the tissue is likely to have lesions through image recognition technology. When the CAD system determines that the removed part of the tissue is a diseased tissue, the probe retracts the clamp channel and carries the diseased tissue out of the clamp channel Colonoscopy pipeline; when the CAD system determines that the removed part of the tissue is normal intestinal tissue or intestinal debris, the probe will expel it and not retract it.
PCT/CN2020/000062 2019-04-25 2020-04-09 Video acquisition system for narrow cavitary space based on microprobe structure WO2020215806A1 (en)

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