WO2020171790A1 - Spring sheathed bladed atherectomy catheter - Google Patents

Spring sheathed bladed atherectomy catheter Download PDF

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Publication number
WO2020171790A1
WO2020171790A1 PCT/TR2020/050089 TR2020050089W WO2020171790A1 WO 2020171790 A1 WO2020171790 A1 WO 2020171790A1 TR 2020050089 W TR2020050089 W TR 2020050089W WO 2020171790 A1 WO2020171790 A1 WO 2020171790A1
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WO
WIPO (PCT)
Prior art keywords
external
catheter
spring
internal
subject
Prior art date
Application number
PCT/TR2020/050089
Other languages
French (fr)
Inventor
Sonay OGUZ
Original Assignee
Canakkale Onsekiz Mart Universitesi Rektorlugu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canakkale Onsekiz Mart Universitesi Rektorlugu filed Critical Canakkale Onsekiz Mart Universitesi Rektorlugu
Publication of WO2020171790A1 publication Critical patent/WO2020171790A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320725—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with radially expandable cutting or abrading elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22065—Functions of balloons
    • A61B2017/22067—Blocking; Occlusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2212—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having a closed distal end, e.g. a loop

Definitions

  • the invention is related to a catheter developed to treat arterial stenoses by non- surgical angiographic methods, aiming at eliminating the hard lesions occurring in the artery by the method of shaving.
  • Vascular occlusions are still a serious problem today and companies are trying to produce many products to eliminate or remove the clot from the body with catheters without the need for surgery.
  • EP3323465 in the known state of the art, it has a catheter system where the first sharpened section and the second fixed diameter coil are fixed together with a wire main body by means of a fixing element and the diameter of this section may also increase in a curved part.
  • the pointed and non-pointed sections where the conical angle is relatively large and the conical angle is relatively small, have a structure that is positioned sequentially. When the catheter tip reaches the lesion, it is possible to bend in a desired position.
  • the invention offers an endovascular two-component catheter tip being flexible, repulsive, radial bending and longitudinal flexibility (e.g. to facilitate the navigation between curved veins).
  • the first component of the catheter tip contains a spring-like structure that provides the desired longitudinal flexibility and repulsiveness of the catheter tip.
  • the second component of the catheter tip provides the distal tip radial stiffness and has a round structure. In this way, it significantly eliminates the rough surface, lesion and congestion of the vessel.
  • the sharp spring structure that will shave the lesion in the catheter tip part should have a feature not to give damage to the vessel and should be able to shave the lesion. Therefore, it has been necessary to develop a catheter that is both sharp enough to shave the lesion easily and would not cause any damage to the vein as it progresses through the vein.
  • the aim of this invention is to develop a catheter that will not only damage the vascular structure but also sharp enough to shave the lesion.
  • Another aim of the present invention is to develop a catheter that will not damage the vein while progressing through the vein.
  • the sharp spring structure to shave the lesion at the tip of the catheter is surrounded by a second spring in a spiral structure that will not damage the vessel. In this way, when the cap is opened, the shaving process will be performed only in the desired area.
  • the protective external spring removes the vein wall from the blades even during shaving.
  • Figure 1 Side view of the external part (introducer) in the catheter being the subject of the invention.
  • Figure 2 Schematic view of the catheter being the subject of the invention without the external part.
  • Figure 3 Schematic view of the catheter being the subject of the invention including the external part.
  • Figure 4 Schematic view of the catheter being the subject of the invention in which the external body is withdrawn.
  • Figure 5 View of the catheter being the subject of the invention in the state where the external body is rotated in one round.
  • Figure 6 View of the catheter being the subject of the invention in the state where the external body is rotated in two rounds.
  • Figure 7 View of the catheter being the subject of the invention in the state where the external body is rotated in three rounds.
  • Figure 8 Schematic view of the external spring in the catheter being the subject of the invention.
  • Figure 9 Schematic view of the internal spring in the catheter being the subject of the invention.
  • Figure 10 Schematic view of the cap in the catheter, being the subject of the invention, when it is open in the vein.
  • Figure 11 Schematic view of the cap in the catheter, being the subject of the invention, when it is shaving the lesion.
  • Figure 12 View of the external spring in the catheter, being the subject of the invention, when the external body is withdrawn.
  • Figure 13 View of the internal spring and external spring section images when the spring tip part is opened in the catheter being the subject of the invention.
  • Figure 14 Schematic view of the internal spring and external spring tips in the catheter, being subject of the invention, when they come into contact with the lesion.
  • the parts in the figures are numbered individually and the equivalents of these numbers are given below.
  • Liquid sending connection The catheter being subject of the invention (1) includes:
  • the catheter (1) being subject of the invention, includes an aspirator connection (8) attached to the internal body (3).
  • the catheter (1) being subject of the invention, includes a stabilizer (10) attached to the external body (2) and the internal body (3).
  • the catheter (1) being subject of the invention, includes a tip balloon (11) located on the external part (introducer part) (15).
  • the catheter (1) being subject of the invention, includes an external part (introducer part) (15). There is a balloon inflation connection (16) and a fluid transmitting connection (17) on the external part (introducer) (15). ( Figure 1)
  • the catheter (1) being subject of the invention, is used to shave lesions (14) that occur within the vessel (13).
  • At the end of the catheter (1) to enter in the vein (13) includes the spring tip part (4) composed of the external spring (5) and the internal spring (6). ( Figure 2-3)
  • the external part (introducer part) (15) in the catheter (1), being subject of the invention, allows the movement of the internal catheter (2). It has no moving element, but is a one-piece structure only with its balloon (11) that may inflate and deflate at its tip. It has a flexible structure. Its purpose is to act as a long sheet and ensure that the internal catheter that will perform the real work flows safely through the vessel.
  • the balloon (11) at the end of this element is inflated during the process, temporarily stopping the blood flow. In this way, it is tried to prevent the ruptured parts from leaking into the lower parts of the vein and creating congestion.
  • This balloon (11) can be inflated and deflated by balloon inflation connection (16).
  • angiographic image can be taken by giving contrast material with fluid transmission connection (17) during the process and the opportunity of obtaining additional images without replacing the catheter is provided in order to perform the processes exactly as desired.
  • the spring tip (4) is closed.
  • the sharp internal spring (6) is surrounded by the non-sharp external spring (5).
  • the external spring (5) surrounds the internal spring (6) preventing the internal spring (6) from damaging the vessel (13) while the catheter (1) is moving through the vessel (13).
  • the internal body (3) and the external body (2) are caused to be kept in this position through the stabilizer (10) .
  • Both the internal sharp spring (6) and the external spring (5) in the catheter (1) extend at equal distance. Otherwise, the springs overlap and cannot perform the desired cutting process.
  • the external spring (5) For the internal spring (6) to perform the shaving process, the external spring (5)) must be pushed by the lesion (14). The spring end (4) is moved forward and back in the lesion (14) region, while the external spring (5) is pushed by the lesion (14) and thus the sharp internal spring (6) reaches the lesion (14) and performs the shaving.
  • the external body (2) In the application of the catheter (1) being subject of the invention, the external body (2) is rotated in the direction of the external spring's (5) spiral structure reducing the diameter of the external spring (5). Similarly, the external body (2) is rotated in the opposite direction of the spiral structure of the external spring (5) increasing the diameter of the external spring (5). In this way, it is possible to use the spring tip (4) in different widths. ( Figure 5-6-7) After the external body (2) is rotated, the external body (2) is kept in this position through the stabilizer (10).
  • the internal body (3) is kept constant and the external body (2) is rotated in the direction of the spring tip (4) causing expansion.
  • the stabilizer (10) has been designed because the spring tends to return to its former state when it is released. It should be noted that the spring may be broken in this process. It will be known in advance how many tours the spring can take according to its alloy feature. There will definitely be no excessive rotation process. (Figure 5-6-7)
  • the aspiration of the lesion (14) parts, that are cut after shaving process is ensured through the aspirator connection (8).
  • the aspiration process in question is like in the catheters known in the technique.
  • the guide wire is inserted from the internal lumen input (9). Similar to the applications known in the technique, the catheter (1) is moved within the vessel (13).
  • the tip balloon (11) in the catheter (1) being subject of the invention, is inflated, preventing the blood flow from stopping during the process and the cut lesion (14) particles from escaping below the vessel (13).

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention is related to a catheter (1) developed to treat arterial stenoses by non-surgical angiographic methods, aiming at eliminating the hard lesions (14) occurring in the artery by the method of shaving. The catheter (1), being subject of the invention, contains a hollow cylinder-shaped external body (2), an internal body (3) in the external body (2), an external spring (5) fixed to one end of the external body (2), a cutting internal spring (6) included in the external spring (5) and fixed to one end of the internal body (3) and a rivet point (12) fixing the external spring (5) and internal spring (6) to each other from their end unconnected with the external body (2) and internal body (3).

Description

SPRING SHEATHED BLADED ATHERECTOMY CATHETER
Technical Field
The invention is related to a catheter developed to treat arterial stenoses by non- surgical angiographic methods, aiming at eliminating the hard lesions occurring in the artery by the method of shaving.
Prior Art
Vascular occlusions are still a serious problem today and companies are trying to produce many products to eliminate or remove the clot from the body with catheters without the need for surgery. There are many atherectomy catheters available on the market to treat such arterial occlusions with non-surgical angiographic methods.
In the catheter systems existing in the technique, the main goal in existing devices is to try to open the vessel by using a cap that is rotated very quickly with the help of a motor. Of course, the greatest fear in this system is the perforation and disintegration of the vein. A technique used in mines is frightening when used in a vein. Due to this concern and high cost, these products could not be widespread. Companies, who thought that the motor and head would be more successful with faster rotation, made users even more concerned. These problems have increased the need to develop a safe shaving method suitable for the vessel.
In the United States document No. US2008161726 in the known state of the art, it has a catheter system where the first small diameter coil has sharpened sharp edges, while the large diameter external coil is relatively safer and the large diameter external coil functions as a sheath. The guide wire, however, passes through the spiral shaped coil and the rotations of the first coil part and the second coil part are in contact with each other. In the United States document No. US6679853 in the known state of the art, it has a catheter system composed of a first coil including a pointed, spiral shaped, radiopaque wire interior of which has a hard structure and a second coil in a protective form with similar thickness. The internal part of the second coil is fastened by solder and so on and the far end of the second coil can be fixed to the first high radiopaque end. This allows to bring the catheter to the desired position.
In the European Patent document No. EP3323465 in the known state of the art, it has a catheter system where the first sharpened section and the second fixed diameter coil are fixed together with a wire main body by means of a fixing element and the diameter of this section may also increase in a curved part. For example, the pointed and non-pointed sections, where the conical angle is relatively large and the conical angle is relatively small, have a structure that is positioned sequentially. When the catheter tip reaches the lesion, it is possible to bend in a desired position.
In the United States document No. US2011196315 in the known state of the art, it is mentioned that the invention offers an endovascular two-component catheter tip being flexible, repulsive, radial bending and longitudinal flexibility (e.g. to facilitate the navigation between curved veins). The first component of the catheter tip contains a spring-like structure that provides the desired longitudinal flexibility and repulsiveness of the catheter tip. The second component of the catheter tip provides the distal tip radial stiffness and has a round structure. In this way, it significantly eliminates the rough surface, lesion and congestion of the vessel.
However, the sharp spring structure that will shave the lesion in the catheter tip part should have a feature not to give damage to the vessel and should be able to shave the lesion. Therefore, it has been necessary to develop a catheter that is both sharp enough to shave the lesion easily and would not cause any damage to the vein as it progresses through the vein.
Aims and Brief Description of the Invention The aim of this invention is to develop a catheter that will not only damage the vascular structure but also sharp enough to shave the lesion.
Another aim of the present invention is to develop a catheter that will not damage the vein while progressing through the vein. The sharp spring structure to shave the lesion at the tip of the catheter is surrounded by a second spring in a spiral structure that will not damage the vessel. In this way, when the cap is opened, the shaving process will be performed only in the desired area. The protective external spring, however, removes the vein wall from the blades even during shaving. Detailed Description of the Invention
The catheter, developed to achieve the objectives of this invention, is shown in the figures.
These figures are;
Figure 1: Side view of the external part (introducer) in the catheter being the subject of the invention.
Figure 2: Schematic view of the catheter being the subject of the invention without the external part.
Figure 3: Schematic view of the catheter being the subject of the invention including the external part. Figure 4: Schematic view of the catheter being the subject of the invention in which the external body is withdrawn.
Figure 5: View of the catheter being the subject of the invention in the state where the external body is rotated in one round. Figure 6: View of the catheter being the subject of the invention in the state where the external body is rotated in two rounds.
Figure 7: View of the catheter being the subject of the invention in the state where the external body is rotated in three rounds. Figure 8: Schematic view of the external spring in the catheter being the subject of the invention.
Figure 9: Schematic view of the internal spring in the catheter being the subject of the invention.
Figure 10: Schematic view of the cap in the catheter, being the subject of the invention, when it is open in the vein.
Figure 11: Schematic view of the cap in the catheter, being the subject of the invention, when it is shaving the lesion.
Figure 12: View of the external spring in the catheter, being the subject of the invention, when the external body is withdrawn. Figure 13: View of the internal spring and external spring section images when the spring tip part is opened in the catheter being the subject of the invention.
Figure 14: Schematic view of the internal spring and external spring tips in the catheter, being subject of the invention, when they come into contact with the lesion. The parts in the figures are numbered individually and the equivalents of these numbers are given below.
1. Catheter
2. External body
3. Internal body 4. Spring end
5. External spring
6. Internal spring
7. Sharp tip
8. Aspirator connection
9. Internal lumen input
10. Stabilizer
11. Tip balloon
12. Rivet point
13. Vessel
14. Lesion
15. External part (Introducer Part)
16. Balloon inflation connection
17. Liquid sending connection The catheter being subject of the invention (1) includes:
An external body (2) in the form of an empty cylinder
An internal body (3) included within the external body (2),
An external spring (5) fixed to one end of the external body (2),
A cutter internal spring (6) included within the external spring (5) and fixed to one end of the internal body (3),
An rivet point (12), where the external spring (5) and the internal spring (6) are fixed each other to the external body (2) and the internal body (3) from their unconnected ends.
The catheter (1), being subject of the invention, includes an aspirator connection (8) attached to the internal body (3). The catheter (1), being subject of the invention, includes an internal lumen input (9) attached to the tip of the internal body (3).
The catheter (1), being subject of the invention, includes a stabilizer (10) attached to the external body (2) and the internal body (3).
The catheter (1), being subject of the invention, includes a tip balloon (11) located on the external part (introducer part) (15).
The catheter (1), being subject of the invention, includes an external part (introducer part) (15). There is a balloon inflation connection (16) and a fluid transmitting connection (17) on the external part (introducer) (15). (Figure 1)
The catheter (1), being subject of the invention, is used to shave lesions (14) that occur within the vessel (13). At the end of the catheter (1) to enter in the vein (13) includes the spring tip part (4) composed of the external spring (5) and the internal spring (6). (Figure 2-3)
The external part (introducer part) (15) in the catheter (1), being subject of the invention, allows the movement of the internal catheter (2). It has no moving element, but is a one-piece structure only with its balloon (11) that may inflate and deflate at its tip. It has a flexible structure. Its purpose is to act as a long sheet and ensure that the internal catheter that will perform the real work flows safely through the vessel. The balloon (11) at the end of this element is inflated during the process, temporarily stopping the blood flow. In this way, it is tried to prevent the ruptured parts from leaking into the lower parts of the vein and creating congestion. This balloon (11) can be inflated and deflated by balloon inflation connection (16). In addition, angiographic image can be taken by giving contrast material with fluid transmission connection (17) during the process and the opportunity of obtaining additional images without replacing the catheter is provided in order to perform the processes exactly as desired. As the catheter (1) travels through the vein (13), the spring tip (4) is closed. In this case, the sharp internal spring (6) is surrounded by the non-sharp external spring (5). The external spring (5) surrounds the internal spring (6) preventing the internal spring (6) from damaging the vessel (13) while the catheter (1) is moving through the vessel (13). (Figure 2-3)
When the lesion (14) is approached, i.e. when shaving begins, the internal body (3) is kept constant and the external body (2) is pulled in the opposite direction of the catheter's (1) progress within the vessel (13). (Figure 4) As a result, the internal body (3) and the internal spring (6) connected to the internal body (3) remain constant. The external body (2) and the external spring (5), however, move in the opposite direction with the pull motion. Since the external spring (5) and the internal spring (6) are fixed to each other from the rivet point (12), one end of the external spring (5) will remain fixed at the rivet point (12) and the other end will move in the opposite direction, the external spring (5) will be opened and extended. As a result of the opening of the spring spirals by extending the external spring (5), the internal spring (6) can reach the lesion (14) area from these spaces. (Figure 10-11)
After the external body (2) is withdrawn, the internal body (3) and the external body (2) are caused to be kept in this position through the stabilizer (10) . Both the internal sharp spring (6) and the external spring (5) in the catheter (1) extend at equal distance. Otherwise, the springs overlap and cannot perform the desired cutting process.
For the internal spring (6) to perform the shaving process, the external spring (5)) must be pushed by the lesion (14). The spring end (4) is moved forward and back in the lesion (14) region, while the external spring (5) is pushed by the lesion (14) and thus the sharp internal spring (6) reaches the lesion (14) and performs the shaving. (Figure 11) In the application of the catheter (1) being subject of the invention, the external body (2) is rotated in the direction of the external spring's (5) spiral structure reducing the diameter of the external spring (5). Similarly, the external body (2) is rotated in the opposite direction of the spiral structure of the external spring (5) increasing the diameter of the external spring (5). In this way, it is possible to use the spring tip (4) in different widths. (Figure 5-6-7) After the external body (2) is rotated, the external body (2) is kept in this position through the stabilizer (10).
The internal body (3) is kept constant and the external body (2) is rotated in the direction of the spring tip (4) causing expansion. The stabilizer (10) has been designed because the spring tends to return to its former state when it is released. It should be noted that the spring may be broken in this process. It will be known in advance how many tours the spring can take according to its alloy feature. There will definitely be no excessive rotation process. (Figure 5-6-7)
In the catheter (1), being subject of the innovation, the aspiration of the lesion (14) parts, that are cut after shaving process, is ensured through the aspirator connection (8). The aspiration process in question is like in the catheters known in the technique.
In the catheter (1), being subject of the catheter, the guide wire is inserted from the internal lumen input (9). Similar to the applications known in the technique, the catheter (1) is moved within the vessel (13).
The tip balloon (11) in the catheter (1), being subject of the invention, is inflated, preventing the blood flow from stopping during the process and the cut lesion (14) particles from escaping below the vessel (13).

Claims

1. The intervention is catheter (1) including:
- An external body (2) in the form of an empty cylinder,
- An internal body (3) included within the external body (2),
- An external spring (5) fixed to one end of the external body (2), and it is characterized by comprising:
- A cutter internal spring (6) included within the external spring (5) and fixed to one end of the internal body (3),
- An rivet point (12), where the external spring (5) and the internal spring (6) are fixed each other to the external body (2) and the internal body (3) from their unconnected ends.
2. The invention is a catheter (1) according to claim 1, characterized by comprising an aspirator connection (8) connected to the internal body (3).
3. The invention is a catheter (1) according to claim 1, characterized by comprising an internal lumen input (9) attached to the end of the internal body (3).
4. The invention is a catheter (1) according to claim 1, characterized by comprising a stabilizer (10) connected to the external body (2) and internal body (3).
5. The invention is a catheter (1) according to claim 1 characterized by comprising an external part (introducer section) (15) in the form of a hollow pipe passing over the external body.
6. The invention is a catheter (1) according to claim 1, characterized with its by comprising a tip balloon (11) located on the external part (introducer section) (15).
PCT/TR2020/050089 2019-02-22 2020-02-10 Spring sheathed bladed atherectomy catheter WO2020171790A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2019/02674A TR201902674A2 (en) 2019-02-22 2019-02-22 SPRING CLAMPED BLADE ATERECTOMY CATHETER
TR2019/02674 2019-02-22

Publications (1)

Publication Number Publication Date
WO2020171790A1 true WO2020171790A1 (en) 2020-08-27

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ID=67955162

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2020/050089 WO2020171790A1 (en) 2019-02-22 2020-02-10 Spring sheathed bladed atherectomy catheter

Country Status (2)

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WO (1) WO2020171790A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366464A (en) * 1993-07-22 1994-11-22 Belknap John C Atherectomy catheter device
US20040002728A1 (en) * 2002-07-01 2004-01-01 Speck Marc L. Coil reinforced multilayered inner tubular member for a balloon catheter
US20110196315A1 (en) * 2010-02-09 2011-08-11 Medinol Ltd. Catheter tip assembled with a spring
WO2016001932A1 (en) * 2014-07-03 2016-01-07 Taryag Medical Ltd. Improved atherectomy device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366464A (en) * 1993-07-22 1994-11-22 Belknap John C Atherectomy catheter device
US20040002728A1 (en) * 2002-07-01 2004-01-01 Speck Marc L. Coil reinforced multilayered inner tubular member for a balloon catheter
US20110196315A1 (en) * 2010-02-09 2011-08-11 Medinol Ltd. Catheter tip assembled with a spring
WO2016001932A1 (en) * 2014-07-03 2016-01-07 Taryag Medical Ltd. Improved atherectomy device

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