WO2020159738A1 - Method for determining j point of electrocardiogram - Google Patents

Method for determining j point of electrocardiogram Download PDF

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Publication number
WO2020159738A1
WO2020159738A1 PCT/US2020/014309 US2020014309W WO2020159738A1 WO 2020159738 A1 WO2020159738 A1 WO 2020159738A1 US 2020014309 W US2020014309 W US 2020014309W WO 2020159738 A1 WO2020159738 A1 WO 2020159738A1
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WIPO (PCT)
Prior art keywords
point
ecg
peak
ekg
amplitude
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PCT/US2020/014309
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French (fr)
Inventor
Tao-wei WANG
Chih-Wen Hung
Ming-Chiuan JING
Shih-Cheng Lan
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Vitalchains Corporation
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Publication of WO2020159738A1 publication Critical patent/WO2020159738A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • A61B5/358Detecting ST segments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • A61B5/36Detecting PQ interval, PR interval or QT interval
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • A61B5/364Detecting abnormal ECG interval, e.g. extrasystoles, ectopic heartbeats

Definitions

  • the present disclosure relates to a method for determining a J point of electrocardiogram, and more particularly, to a method for determining a J point of electrocardiogram through geometric analysis.
  • MI Myocardial infarction
  • AMI acute myocardial infarction
  • STEMI ST-segment elevation MI
  • STEMI electrocardiogram
  • Another method is to directly find a peak between the S point and T wave or a position with largest curvature, but this method is easily affected by the noise signal of ECG/EKG, thereby leading incorrectness or difficulty to find the J point by algorithm and locating instability.
  • An embodiment of the present invention provides a method for automatic determining a J point of an electrocardiogram (ECG/EKG), in which the method includes providing an ECG/EKG complex, providing a reference S peak, a reference T peak and a reference baseline of the ECG/EKG complex, and performing a J point locating process of the ECG/EKG complex according to the reference S peak, the reference T peak and the reference baseline by a geometric analysis.
  • ECG/EKG electrocardiogram
  • FIG. 1 schematically illustrates a system for determining a J point of an electrocardiogram (ECG/EKG) according to an embodiment of the present invention.
  • FIG. 2 schematically illustrates a flowchart of a method for diagnosing the STEMI according to the present invention.
  • FIG. 3 schematically illustrates a flowchart of a method for determining the J point of the ECG/EKG according to an embodiment of the present invention
  • FIG. 4 schematically illustrates a normal segmented ECG/EKG complex.
  • FIG. 5 A schematically illustrates a first example of a segmented ECG/EKG complex of a first geometry analysis mode.
  • FIG. 5B schematically illustrates a second example of a segmented ECG/EKG complex of the first geometry analysis mode.
  • FIG. 5C schematically illustrates a third example of a segmented ECG/EKG complex of the first geometry analysis mode.
  • FIG. 6A schematically illustrates a first example of a segmented ECG/EKG complex of a second geometry analysis mode.
  • FIG. 6B schematically illustrates a second example of a segmented ECG/EKG complex of the second geometry analysis mode.
  • FIG. 7A schematically illustrates a first example of a segmented ECG/EKG complex of a third geometry analysis mode.
  • FIG. 7B schematically illustrates a second example of a segmented ECG/EKG complex of a third geometry analysis mode.
  • FIG. 8 schematically illustrates an example of a segmented ECG/EKG complex of a fourth geometry analysis mode.
  • FIG. 1 schematically illustrates a system for determining a J point of an
  • the system 1 includes a plurality of ECG/EKG electrodes for detecting and receiving the
  • the ECG/EKG system 12 is operatively coupled to a patient by attaching 10 ECG/EKG electrodes, such as electrodes VI, V2, V3, V4, V5, V6, RA, LA, RL and LL, to the body of the patient, so as to detect signals of 12 leads (I, II, III, aVR, aVL, a VF, VI, V2, V3, V4, V5 and V6) of the ECG/EKG.
  • the ECG/EKG electrodes detect signals and transmit the signals to the ECG/EKG system 12 for further processing thereby the J point can be determined.
  • the ECG/EKG system 12 may include a digital signal processing unit 14 for determining the J point by geometry analysis.
  • the digital signal processing unit 14 may optionally include a discrete Fourier
  • transforming unit for inhibiting or enhancing signals in frequency domain, a signal segmenting unit for segmenting the digital signal, or a pattern recognition unit for determining PQRST complex waveforms and/or P/Q/R/S/T points.
  • the ECG/EKG electrodes may collect analog ECG/EKG signals.
  • the ECG/EKG system 12 may further include an analog signal processing unit 16 and an A/D converting unit 18 for processing the analog signal into a digital signal for further geometry analysis.
  • the analog signal processing unit 16 may optionally include filter, amplifier, level shifter or rectifier, but not limited thereto.
  • the ECG/EKG system 12 may further include an input/output unit 20, and the input/output unit 20 such as display panel or printer for showing the ECG/EKG may assist doctor to make a diagnosis.
  • the ECG/EKG electrodes may collect digital signal and thus the digital ECG/EKG signal is transmitted to the digital signal processing unit 14 directly.
  • the following method for determining the J point is not limited to be applied to the digital signal processing unit 14 of the above-mentioned system 1.
  • FIG. 2 schematically illustrates a flowchart of a method for diagnosing the STEMI according to the present invention.
  • the method for diagnosing the STEMI may include steps SI 2, SI 4, SI 6, S18 and S20, which are automatically performed by the above system 1.
  • the step S12 is performed to providing an ECG/EKG for example by the ECG/EKG electrodes, but is not limited thereto.
  • the step S14 is performed to pre-process the ECG/EKG, such as filtering, smoothing or segmenting the ECG/EKG.
  • the step S16 is performed to recognize the pattern of the processed ECG/EKG and followed by performing the step SI 8 to extract the feature (e.g. to determine the J point) of the pattern.
  • the steps SI 4, S16 and SI 8 may be performed by the ECG/EKG system 12 for example, but is not limited thereto.
  • the result containing the feature e.g. the position of the J point
  • the steps shown in the method are not exhaustive and that other steps may be performed as well before, after, or between any of the illustrated steps.
  • FIG. 3 schematically illustrates a flowchart of a method for determining the J point of the ECG/EKG according to an embodiment of the present invention
  • FIG. 4 schematically illustrates a segmented ECG/EKG complex.
  • the method for determining the J point of the ECG/EKG complex is described in conjunction with FIG. 3 as well as FIG. 1 and FIG. 2.
  • the method for determining the J point may include following steps SI 02, SI 04, SI 06, S108, S110A, S110B, S110C, SHOD, and S 112.
  • the ECG/EKG is provided in the step S102(corresponding to step S12).
  • the ECG/EKG may be measured and recorded by utilizing the ECG/EKG electrodes to receive the
  • the ECG/EKG electrodes may be for example implemented in a wearable device, such as smart watch, a mobile ECG machine, smart phone, or other suitable devices.
  • the ECG/EKG may include a plurality of signals of 12 leads.
  • the ECG/EKG may be a multi-leads ECG/EKG, such as 3 -leads, 5-leads, or 12-leads.
  • step S104 a plurality of segmented ECG/EKG complexes 100 are provided by pre-process the ECG/EKG.
  • the ECG/EKG For example, the
  • ECG/EKG may be segmented into the segmented ECG/EKG complexes 100 by the digital signal processing unit 14 shown in FIG. 1, but the present invention is not limited thereto.
  • FIG. 4 shows one segmented ECG/EKG complex 100, and the shape of the segmented ECG/EKG complex 100 is for an example, but not limited thereto.
  • the segmented ECG/EKG complex 100 may be one ECG cardiac cycle of the signal of any one of 12 leads.
  • the segmented ECG/EKG complex 100 may be one ECG cardiac cycle of lead V2 or lead V3, for example, the segmented ECG/EKG complex 100 may include one PQRST complex W1 as shown in FIG. 4.
  • the segmented ECG/EKG complex 100 may be implemented to one ECG cardiac cycle of any lead.
  • an ECG/EKG complex may be provided, and the ECG/EKG complex may include a plurality of PQRST complexes Wl .
  • the term“segmented ECG/EKG complex” mentioned in the following description may refer to as the segmented ECG/EKG complex 100 including one PQRST complex Wl or the ECG/EKG complex including a plurality of PQRST complexes Wl.
  • the segmented ECG/EKG complexes 100 may be provided by performing the pre-processing step S14.
  • a segmenting method in the pre-processing step S14 may for example include finding R peaks 102 of the ECG/EKG complex to define different segmented ECG/EKG complexes and then segmenting the ECG/EKG complex into one another, so as to obtain the segmented ECG/EKG complexes 100.
  • the segmenting method of the present invention is not limited thereto.
  • the segmented ECG/EKG complex 100 in FIG. 4 is a normal segmented ECG/EKG complex, but not limited thereto.
  • the segmented ECG/EKG complex 100 may be any segmented ECG/EKG complex with any kind of shape detected from any person. Horizontal axis and vertical axis of FIG. 4 are time and voltage respectively.
  • a reference S peak 104, a reference T peak 106 and a reference baseline 108 of the segmented ECG/EKG complex 100 may be provided, for example by the ECG/EKG system 12.
  • the pattern of the segmented ECG/EKG complex 100 may be recognized by the
  • the reference S peak 104 of the QRS complex, the reference T peak 106 of the T wave and the reference baseline 108 can be found, and their corresponding amplitudes, such as an amplitude AS of the reference S peak 104, an amplitude AT of the reference T peak 106 and an amplitude of the reference baseline 108, may be obtained.
  • the amplitude (e.g. voltage relative to 0 voltage) of the reference baseline 108 may be an average, a median, a mode or another suitable statistic value of a PR segment 116 of the segmented ECG/EKG complex 100.
  • the amplitude AS of the reference S peak 104 may be a voltage difference between the reference S peak 104 and 0 voltage
  • the amplitude AT of the reference T peak 106 may be a voltage difference between the reference T peak 106 and 0 voltage
  • the amplitude of the reference baseline 108 may be a voltage difference between the reference baseline 108 and 0 voltage.
  • the reference S peak 104 may be a medical S peak.
  • the T peak 106 may be a medical T peak.
  • the reference S peak 104 may not be a medical S peak, but a peak for algorithm.
  • the reference T peak 106 may not be a medical T peak, but a peak for algorithm.
  • a J point locating process SI 14 of the segmented ECG/EKG complex 100 is performed by a geometry analysis according to the reference S peak 104, the reference T peak 106 and the reference baseline 108, for example according to the amplitude AS of the reference S peak 104, the amplitude AT of the reference T peak 106 and the amplitude of the reference baseline 108.
  • the J point locating process SI 14 may include step S108 and steps S110A, S110B, S110C, SHOD
  • the amplitude AS of the reference S peak 104 is compared with the amplitude of the reference baseline 108
  • the amplitude AT of the reference T peak 106 is compared with the amplitude of the reference baseline 108, so as to determine which geometry analysis mode the segmented ECG/EKG complex 100 measured from patient is.
  • the steps shown in the J point locating process SI 14 of the segmented ECG/EKG complex 100 may be not exhaustive and that other steps may be performed as well before, after, or between any of the illustrated steps.
  • FIG. 5 A schematically illustrates a first example of a segmented ECG/EKG complex of a first geometry analysis mode.
  • the segmented ECG/EKG complex 100a is determined as the first geometry analysis mode, and a secant line 110a passing through the reference S peak 104a and the reference T peak 106a (indicated as a dotted line shown in FIG. 5 A) is formed and obtained.
  • the step S 110A may further include determining the reference J point 112a according to the first geometry analysis mode, the segmented ECG/EKG complex 100a and the secant line 110a by geometry analysis. Specifically, in the step of determining the reference J point 112a, an amplitude of the segmented ECG/EKG complex 100a is compared with an amplitude of the secant line 110a to determine whether an amplitude of at least one part of a segment 118a of the segmented ECG/EKG complex 100a between the reference S peak 104a and the reference T peak 106a is greater than the amplitude of the secant line 110a and to obtain which example of the first geometry analysis mode the segmented ECG/EKG complex 100a is.
  • the comparison in amplitude between the segment 118a and the secant line 110a is that an amplitude of one point on the segment 118a is compared with an amplitude of another point on the secant line at the same time as the point, and when the amplitude of the point of the segment 118a is greater than the amplitude of the another point on the secant line 110a, the part of the point of the segment 118a is defined as being above the secant line 110a.
  • amplitudes of all parts of the segment 118a is greater than the amplitude of the secant line 110a, i.e.
  • the segmented ECG/EKG complex 100a is determined as the first example of the first geometry analysis mode.
  • the step of determining the reference J point 112a may include obtaining a point on the segment 118a that is farthest from the secant line 110a, and the point farthest from the secant line 110a may be determined as the reference J point 112a.
  • the step of obtaining the point may include calculating minimum distances D between a plurality of points on the segment 118a and the secant line 110a, and the point determined as the reference J point 112a is the one of the points with largest one of the minimum distances D.
  • the minimum distances D between the points of the segment 118a and the secant line 110a may be obtained by calculating perpendicular distances between the points on the segment 118a and the secant line 110a; that is, the reference J point 112a may be determined according to a perpendicular distance between the segmented ECG/EKG complex 100a and the secant line 110a.
  • distances between the points on the segment 118a and the projections of the points projected on the secant line 110a may be calculated, wherein the projections of the points are projected on the secant line 110a along a direction PD perpendicular to the secant line 110a.
  • the reference J point 112a the point with the largest one of the distances from the secant line 110a is determined as the reference J point 112a, and accordingly, the reference J point 112a can be located.
  • the reference J point 112a may be a medical J point, or may not be the medical J point, but a point for algorithm.
  • FIG. 5B schematically illustrates a second example of a segmented ECG/EKG complex of the first geometry analysis mode.
  • at least one part of the segment 118b of the segmented ECG/EKG complex 100b between the reference S peak 104b and the reference T peak 106b may be less than the secant line 110b, which means points of the at least one part of the segment 118b have amplitudes less than an amplitude of a corresponding point on the secant line 110b, so the segmented ECG/EKG complex 100b is determined as a second example of the first geometry analysis mode.
  • the step of determining the reference J point 112b may include obtaining a point on the other part of the segment 118b that is farthest from the secant line 110b, and the point farthest from the secant line 110b may be determined as the reference J point 112b.
  • the step of obtaining the point may include calculating minimum distances D between a plurality of points on the other part of the segment 118b and the secant line 110b, and the point determined as the reference J point 112b is the one of the points with largest one of the minimum distances D.
  • the minimum distances D between the points of the other part of the segment 118b and the secant line 110b may be obtained by calculating perpendicular distances between the points on the other part of the segment 118b and the secant line 110b; that is, the reference J point 112b may be determined according to a perpendicular distance between the segmented ECG/EKG complex 100b and the secant line 110b.
  • distances between the points on the other part of the segment 118b and the projections of the points projected on the secant line 110b may be calculated, wherein the projections of the points are projected on the secant line 110b along a direction PD perpendicular to the secant line 110b.
  • the distances between points on the other part of the segment 118b above the secant line 110b (that is other part of the segment 118b other than the at least one part) and the projections of the points of the other part of the segment 118b projected on the secant line 110b may be calculated in the step S110A shown in FIG. 3, and the point with the largest distance from the secant line 110b is determined as the reference J point 112b, such that the reference J point 112b can be located.
  • FIG. 5C schematically illustrates a third example of a segmented ECG/EKG complex of the first geometry analysis mode.
  • the segmented ECG/EKG complex 100c is determined as a third example of the first geometry analysis mode, and the reference S peak 104c is determined as the reference J point 112c in the step S110A.
  • FIG. 6A schematically illustrates a first example of a segmented ECG/EKG complex of a second geometry analysis mode.
  • the segmented ECG/EKG complex lOOd is determined as the second geometry analysis mode, and a secant line llOd passing through the reference S peak 104d and the reference T peak 106d can be obtained (indicated as a dotted line shown in FIG. 6 A).
  • the reference J point 112d is determined according to the second geometry analysis mode, the segmented ECG/EKG complex lOOd and the secant line llOd by geometry analysis.
  • the step S110B may further include firstly determining whether a slope of the secant line llOd is greater than 0 to obtain which example the segmented ECG/EKG complex lOOd is. When the slope of the secant line llOd is greater than 0, the segmented ECG/EKG complex lOOd is determined as the first example of the second geometry analysis mode.
  • an amplitude of the segmented ECG/EKG complex lOOd is compared with an amplitude of the secant line llOd to determine whether an amplitude of at least one part of a segment 118d of the segmented ECG/EKG complex lOOd between the reference S peak 104d and the reference T peak 106d is greater than the amplitude of the secant line llOd.
  • the amplitude of at least one part of the segment 118d is greater than the amplitude of the secant line llOd, i.e.
  • the step of determining the reference J point 112d may include obtaining a point on the at least one part of the segment 118d that is farthest from the secant line llOd, and the point farthest from the secant line llOd may be determined as the reference J point 112d.
  • the step of obtaining the point may include calculating minimum distances D between a plurality of points on the at least one part of the segment 118d and the secant line llOd, and the point determined as the reference J point 112d is the one of the points with largest one of the minimum distances D.
  • the minimum distances D between the points of the at least one part of the segment 118d and the secant line llOd may be obtained by calculating perpendicular distances between the points on the at least one part of the segment 118d and the secant line llOd.
  • distances between the points on the at least one part of the segment 118d and the projections of the points projected on the secant line llOd may be calculated, wherein the projections of the points are projected on the secant line llOd along a direction PD perpendicular to the secant line llOd.
  • distances between the points on the at least one part of the segment 118d and the projections of the points projected on the secant line llOd are calculated in the step S110B, and then, the point with the largest distance from the secant line llOd is determined as the reference J point 112d. Accordingly, the reference J point 112d can be located.
  • FIG. 6B schematically illustrates a second example of a segmented ECG/EKG complex of the second geometry analysis mode.
  • the segmented ECG/EKG complex lOOe is determined as a second example of the second geometry analysis mode, and in such example, the reference S peak 104e is determined as the reference J point 112e.
  • FIG. 7A schematically illustrates a first example of a segmented ECG/EKG complex of a third geometry analysis mode. As shown in FIG. 7A and FIG.
  • the segmented ECG/EKG complex lOOf is determined as the third geometry analysis mode
  • the reference S peak 104f is determined as the reference J point 112f.
  • an amplitude of a medical S peak is greater than the amplitude of the reference baseline
  • the reference S peak 104f is the medical S peak
  • the reference T peak 106f is the medical T peak, but not limited thereto.
  • FIG. 7B schematically illustrates a second example of a segmented ECG/EKG complex of a third geometry analysis mode.
  • the reference S peak 104g (that is S’ shown in FIG. 7B) may be different from the medical S peak 114 (that is S shown in FIG. 7B).
  • the segmented ECG/EKG complex lOOg may have a medical S peak 114 different from the reference S peak 104g, and an amplitude of the medical S peak 114 is less than the amplitude of the reference baseline 108.
  • the reference S peak 104g is also determined as the reference J point 112g.
  • the segmented ECG/EKG complex lOOg may for example have rSr’ pattern in the second example of the third geometry analysis mode.
  • FIG. 8 schematically illustrates an example of a segmented ECG/EKG complex of a fourth geometry analysis mode.
  • the segmented ECG/EKG complex lOOh is determined as the fourth geometry analysis mode, and the reference S peak 104h is determined as the reference J point 112h.
  • the reference J point can be sought and located in the segmented ECG/EKG complex measured from the patient, thereby finding corresponding ST segment.
  • the information of reference J point may be sent or shown to the doctor, a patient, or AI data analytics.
  • the patient may be warned by the information to hospital, or the doctor may determine the symptom of the patient by the support of the information, such as determine whether voltage of the ST segment is greater than the standard of AHA (American Heart Association).
  • AHA American Heart Association
  • the reference J point may be found according to signal of one lead instead of requiring all signals of 12 leads, and the reference J point can be easily found based on the determination of four geometry analysis modes with reduced calculation power such as mobile ECG/EKG device, so as to faster locating the reference J point and reduce

Abstract

A method for determining a J point of an electrocardiogram (ECG/EKG) is disclosed and includes the following steps. First, an ECG/EKG complex is provided. Then, a reference S peak, a reference T peak and a reference baseline of the ECG/EKG complex are provided. After that, a J point locating process of the ECG/EKG complex is performed according to the reference S peak, the reference T peak and the reference baseline by a geometric analysis.

Description

METHOD FOR DETERMINING J POINT OF ELECTROCARDIOGRAM
Background of the Disclosure
1. Field of the Disclosure
The present disclosure relates to a method for determining a J point of electrocardiogram, and more particularly, to a method for determining a J point of electrocardiogram through geometric analysis.
2. Description of the Prior Art
Myocardial infarction (MI) can be classified into general MI and acute myocardial infarction (AMI). In AMI, ST-segment elevation MI (STEMI) is a life-threatening, time-sensitive emergency, and as implied by its name, STEMI is found by detecting ST-segment elevation on the results of 12-lead of an
electrocardiogram (ECG/EKG). Since prognosis condition of STEMI is significantly related to the time of revascularization in the cardiac catheterization room, STEMI should be diagnosed as soon as possible to reduce the Door-to-Balloon time of patient and improve prognosis condition of the patient. Usually, the ST segment is determined by finding the position of J point that is defined as the point marking the end of the QRS complex and the beginning of the ST segment.
However, it is difficult to determine exactly where the J point of the ECG/EKG is. For this reason, some methods are provided to assist doctor or patient to be aware that the patient has STEMI. One of these methods is to locate the J point through finding a point of ECG/EKG with smallest variation after the QRS complex in all signals of 12 leads because the J point is found at the point. However, because MI may occur at different positions of heart, ECG/EKG signals of STEMI in different leads have different waveforms, and this method requires all signals of 12 leads.
Accordingly, it is difficult and of heavy-loaded calculation to obtain accurate position of the J point through this method. Another method is to directly find a peak between the S point and T wave or a position with largest curvature, but this method is easily affected by the noise signal of ECG/EKG, thereby leading incorrectness or difficulty to find the J point by algorithm and locating instability.
Summary An embodiment of the present invention provides a method for automatic determining a J point of an electrocardiogram (ECG/EKG), in which the method includes providing an ECG/EKG complex, providing a reference S peak, a reference T peak and a reference baseline of the ECG/EKG complex, and performing a J point locating process of the ECG/EKG complex according to the reference S peak, the reference T peak and the reference baseline by a geometric analysis.
These and other objectives of the present disclosure will no doubt become obvious to those of ordinary skill in the art after reading the following detailed description of the embodiment that is illustrated in the various figures and drawings.
Brief Description of Drawings
FIG. 1 schematically illustrates a system for determining a J point of an electrocardiogram (ECG/EKG) according to an embodiment of the present invention.
FIG. 2 schematically illustrates a flowchart of a method for diagnosing the STEMI according to the present invention.
FIG. 3 schematically illustrates a flowchart of a method for determining the J point of the ECG/EKG according to an embodiment of the present invention
FIG. 4 schematically illustrates a normal segmented ECG/EKG complex.
FIG. 5 A schematically illustrates a first example of a segmented ECG/EKG complex of a first geometry analysis mode.
FIG. 5B schematically illustrates a second example of a segmented ECG/EKG complex of the first geometry analysis mode.
FIG. 5C schematically illustrates a third example of a segmented ECG/EKG complex of the first geometry analysis mode.
FIG. 6A schematically illustrates a first example of a segmented ECG/EKG complex of a second geometry analysis mode.
FIG. 6B schematically illustrates a second example of a segmented ECG/EKG complex of the second geometry analysis mode.
FIG. 7A schematically illustrates a first example of a segmented ECG/EKG complex of a third geometry analysis mode.
FIG. 7B schematically illustrates a second example of a segmented ECG/EKG complex of a third geometry analysis mode.
FIG. 8 schematically illustrates an example of a segmented ECG/EKG complex of a fourth geometry analysis mode.
Detailed Description
The present invention may be understood by reference to the following detailed description, taken in conjunction with the drawings as described below. It is noted that, for purposes of illustrative clarity and being easily understood by the readers, various drawings of this disclosure show a portion of electrocardiogram(ECG/EKG) or a portion of system, and certain patterns in various drawings may not be drawn to scale. In addition, the number and dimension of each pattern shown in drawings are only illustrative and are not intended to limit the scope of the present disclosure.
FIG. 1 schematically illustrates a system for determining a J point of an
ECG/EKG according to an embodiment of the present invention. The system 1 includes a plurality of ECG/EKG electrodes for detecting and receiving the
ECG/EKG signal and an ECG/EKG system 12 for determining the J point of
ECG/EKG. The ECG/EKG system 12 is operatively coupled to a patient by attaching 10 ECG/EKG electrodes, such as electrodes VI, V2, V3, V4, V5, V6, RA, LA, RL and LL, to the body of the patient, so as to detect signals of 12 leads (I, II, III, aVR, aVL, a VF, VI, V2, V3, V4, V5 and V6) of the ECG/EKG. In the present invention, the ECG/EKG electrodes detect signals and transmit the signals to the ECG/EKG system 12 for further processing thereby the J point can be determined.
In this embodiment, the ECG/EKG system 12 may include a digital signal processing unit 14 for determining the J point by geometry analysis. For example, the digital signal processing unit 14 may optionally include a discrete Fourier
transforming unit for inhibiting or enhancing signals in frequency domain, a signal segmenting unit for segmenting the digital signal, or a pattern recognition unit for determining PQRST complex waveforms and/or P/Q/R/S/T points. In some
embodiments, the ECG/EKG electrodes may collect analog ECG/EKG signals. In such situation, the ECG/EKG system 12 may further include an analog signal processing unit 16 and an A/D converting unit 18 for processing the analog signal into a digital signal for further geometry analysis. In some embodiments, the analog signal processing unit 16 may optionally include filter, amplifier, level shifter or rectifier, but not limited thereto. In some embodiments, the ECG/EKG system 12 may further include an input/output unit 20, and the input/output unit 20 such as display panel or printer for showing the ECG/EKG may assist doctor to make a diagnosis.
In some embodiments, the ECG/EKG electrodes may collect digital signal and thus the digital ECG/EKG signal is transmitted to the digital signal processing unit 14 directly. The following method for determining the J point is not limited to be applied to the digital signal processing unit 14 of the above-mentioned system 1.
FIG. 2 schematically illustrates a flowchart of a method for diagnosing the STEMI according to the present invention. In one embodiment, the method for diagnosing the STEMI may include steps SI 2, SI 4, SI 6, S18 and S20, which are automatically performed by the above system 1. First, the step S12 is performed to providing an ECG/EKG for example by the ECG/EKG electrodes, but is not limited thereto. Then, the step S14 is performed to pre-process the ECG/EKG, such as filtering, smoothing or segmenting the ECG/EKG. Later, the step S16 is performed to recognize the pattern of the processed ECG/EKG and followed by performing the step SI 8 to extract the feature (e.g. to determine the J point) of the pattern. In one embodiment, the steps SI 4, S16 and SI 8 may be performed by the ECG/EKG system 12 for example, but is not limited thereto. Subsequently, in the step S20, the result containing the feature (e.g. the position of the J point) can be provided to the doctor, the patient, or AI data analytics for assisting the doctor or the patient to have further clinical decision support. It should be understood that the steps shown in the method are not exhaustive and that other steps may be performed as well before, after, or between any of the illustrated steps.
The method used for determining the J point of the ECG/EKG is exemplified and detailed in the following description. FIG. 3 schematically illustrates a flowchart of a method for determining the J point of the ECG/EKG according to an embodiment of the present invention, and FIG. 4 schematically illustrates a segmented ECG/EKG complex. The method for determining the J point of the ECG/EKG complex is described in conjunction with FIG. 3 as well as FIG. 1 and FIG. 2. As shown in FIG. 3, the method for determining the J point may include following steps SI 02, SI 04, SI 06, S108, S110A, S110B, S110C, SHOD, and S 112. First, in the step S102(corresponding to step S12), the ECG/EKG is provided. For example, the ECG/EKG may be measured and recorded by utilizing the ECG/EKG electrodes to receive the
ECG/EKG signal from a patient for such as about 60 seconds. The ECG/EKG electrodes may be for example implemented in a wearable device, such as smart watch, a mobile ECG machine, smart phone, or other suitable devices. In one embodiment, the ECG/EKG may include a plurality of signals of 12 leads. In some embodiments, the ECG/EKG may be a multi-leads ECG/EKG, such as 3 -leads, 5-leads, or 12-leads.
In step S104(corresponding to step SI 4), a plurality of segmented ECG/EKG complexes 100 are provided by pre-process the ECG/EKG. For example, the
ECG/EKG may be segmented into the segmented ECG/EKG complexes 100 by the digital signal processing unit 14 shown in FIG. 1, but the present invention is not limited thereto. For clarity, FIG. 4 shows one segmented ECG/EKG complex 100, and the shape of the segmented ECG/EKG complex 100 is for an example, but not limited thereto. It is noted that the segmented ECG/EKG complex 100 may be one ECG cardiac cycle of the signal of any one of 12 leads. In one embodiment, the segmented ECG/EKG complex 100 may be one ECG cardiac cycle of lead V2 or lead V3, for example, the segmented ECG/EKG complex 100 may include one PQRST complex W1 as shown in FIG. 4. In one embodiment, the segmented ECG/EKG complex 100 may be implemented to one ECG cardiac cycle of any lead. In some embodiments, in step SI 04, an ECG/EKG complex may be provided, and the ECG/EKG complex may include a plurality of PQRST complexes Wl . The term“segmented ECG/EKG complex” mentioned in the following description may refer to as the segmented ECG/EKG complex 100 including one PQRST complex Wl or the ECG/EKG complex including a plurality of PQRST complexes Wl.
In one embodiment, the segmented ECG/EKG complexes 100 may be provided by performing the pre-processing step S14. In such situation, a segmenting method in the pre-processing step S14 may for example include finding R peaks 102 of the ECG/EKG complex to define different segmented ECG/EKG complexes and then segmenting the ECG/EKG complex into one another, so as to obtain the segmented ECG/EKG complexes 100. The segmenting method of the present invention is not limited thereto. The segmented ECG/EKG complex 100 in FIG. 4 is a normal segmented ECG/EKG complex, but not limited thereto. The segmented ECG/EKG complex 100 may be any segmented ECG/EKG complex with any kind of shape detected from any person. Horizontal axis and vertical axis of FIG. 4 are time and voltage respectively.
In step S106(corresponding to step SI 6), a reference S peak 104, a reference T peak 106 and a reference baseline 108 of the segmented ECG/EKG complex 100 may be provided, for example by the ECG/EKG system 12. In this embodiment, the pattern of the segmented ECG/EKG complex 100 may be recognized by the
ECG/EKG system 12, such that a P wave, a QRS complex and a T wave may be identified. Accordingly, the reference S peak 104 of the QRS complex, the reference T peak 106 of the T wave and the reference baseline 108 can be found, and their corresponding amplitudes, such as an amplitude AS of the reference S peak 104, an amplitude AT of the reference T peak 106 and an amplitude of the reference baseline 108, may be obtained. For example, the amplitude (e.g. voltage relative to 0 voltage) of the reference baseline 108 may be an average, a median, a mode or another suitable statistic value of a PR segment 116 of the segmented ECG/EKG complex 100. For example, the amplitude AS of the reference S peak 104 may be a voltage difference between the reference S peak 104 and 0 voltage, the amplitude AT of the reference T peak 106 may be a voltage difference between the reference T peak 106 and 0 voltage, and the amplitude of the reference baseline 108 may be a voltage difference between the reference baseline 108 and 0 voltage. In one embodiment, the reference S peak 104 may be a medical S peak. The T peak 106 may be a medical T peak. In some embodiments, the reference S peak 104 may not be a medical S peak, but a peak for algorithm. The reference T peak 106 may not be a medical T peak, but a peak for algorithm.
After step SI 06, a J point locating process SI 14 of the segmented ECG/EKG complex 100 is performed by a geometry analysis according to the reference S peak 104, the reference T peak 106 and the reference baseline 108, for example according to the amplitude AS of the reference S peak 104, the amplitude AT of the reference T peak 106 and the amplitude of the reference baseline 108. Specifically, the J point locating process SI 14 may include step S108 and steps S110A, S110B, S110C, SHOD In the step SI 08, the amplitude AS of the reference S peak 104 is compared with the amplitude of the reference baseline 108, and the amplitude AT of the reference T peak 106 is compared with the amplitude of the reference baseline 108, so as to determine which geometry analysis mode the segmented ECG/EKG complex 100 measured from patient is. It should be understood that the steps shown in the J point locating process SI 14 of the segmented ECG/EKG complex 100 may be not exhaustive and that other steps may be performed as well before, after, or between any of the illustrated steps.
FIG. 5 A schematically illustrates a first example of a segmented ECG/EKG complex of a first geometry analysis mode. As shown in FIG. 5A and FIG. 3, in step SI 10A, when the amplitude of the reference S peak 104a is less than the amplitude of the reference baseline 108, and the amplitude of the reference T peak 106a is greater than the amplitude of the reference baseline 108, the segmented ECG/EKG complex 100a is determined as the first geometry analysis mode, and a secant line 110a passing through the reference S peak 104a and the reference T peak 106a (indicated as a dotted line shown in FIG. 5 A) is formed and obtained. After that, the step S 110A may further include determining the reference J point 112a according to the first geometry analysis mode, the segmented ECG/EKG complex 100a and the secant line 110a by geometry analysis. Specifically, in the step of determining the reference J point 112a, an amplitude of the segmented ECG/EKG complex 100a is compared with an amplitude of the secant line 110a to determine whether an amplitude of at least one part of a segment 118a of the segmented ECG/EKG complex 100a between the reference S peak 104a and the reference T peak 106a is greater than the amplitude of the secant line 110a and to obtain which example of the first geometry analysis mode the segmented ECG/EKG complex 100a is. The comparison in amplitude between the segment 118a and the secant line 110a is that an amplitude of one point on the segment 118a is compared with an amplitude of another point on the secant line at the same time as the point, and when the amplitude of the point of the segment 118a is greater than the amplitude of the another point on the secant line 110a, the part of the point of the segment 118a is defined as being above the secant line 110a. In the example of FIG. 5 A, when amplitudes of all parts of the segment 118a is greater than the amplitude of the secant line 110a, i.e. all parts of the segment 118a are disposed above the secant line 110a, the segmented ECG/EKG complex 100a is determined as the first example of the first geometry analysis mode. Then, the step of determining the reference J point 112a may include obtaining a point on the segment 118a that is farthest from the secant line 110a, and the point farthest from the secant line 110a may be determined as the reference J point 112a. The step of obtaining the point may include calculating minimum distances D between a plurality of points on the segment 118a and the secant line 110a, and the point determined as the reference J point 112a is the one of the points with largest one of the minimum distances D. For example, the minimum distances D between the points of the segment 118a and the secant line 110a may be obtained by calculating perpendicular distances between the points on the segment 118a and the secant line 110a; that is, the reference J point 112a may be determined according to a perpendicular distance between the segmented ECG/EKG complex 100a and the secant line 110a. In detailed, distances between the points on the segment 118a and the projections of the points projected on the secant line 110a may be calculated, wherein the projections of the points are projected on the secant line 110a along a direction PD perpendicular to the secant line 110a. Thereafter, the point with the largest one of the distances from the secant line 110a is determined as the reference J point 112a, and accordingly, the reference J point 112a can be located. In the disclosure, the reference J point 112a may be a medical J point, or may not be the medical J point, but a point for algorithm.
FIG. 5B schematically illustrates a second example of a segmented ECG/EKG complex of the first geometry analysis mode. In some embodiments, as shown in FIG. 5B, at least one part of the segment 118b of the segmented ECG/EKG complex 100b between the reference S peak 104b and the reference T peak 106b may be less than the secant line 110b, which means points of the at least one part of the segment 118b have amplitudes less than an amplitude of a corresponding point on the secant line 110b, so the segmented ECG/EKG complex 100b is determined as a second example of the first geometry analysis mode. In such situation, the at least one part of the segment 118b below the secant line 110b is determined to be ignored, which for example means the minimum distances D between the at least one part and the secant line 110b are not calculated and the amplitudes of the at least one part are not compared with the secant line 110b. Thus, in the second example of FIG. 5B, the step of determining the reference J point 112b may include obtaining a point on the other part of the segment 118b that is farthest from the secant line 110b, and the point farthest from the secant line 110b may be determined as the reference J point 112b. The step of obtaining the point may include calculating minimum distances D between a plurality of points on the other part of the segment 118b and the secant line 110b, and the point determined as the reference J point 112b is the one of the points with largest one of the minimum distances D. For example, the minimum distances D between the points of the other part of the segment 118b and the secant line 110b may be obtained by calculating perpendicular distances between the points on the other part of the segment 118b and the secant line 110b; that is, the reference J point 112b may be determined according to a perpendicular distance between the segmented ECG/EKG complex 100b and the secant line 110b. In detailed, distances between the points on the other part of the segment 118b and the projections of the points projected on the secant line 110b may be calculated, wherein the projections of the points are projected on the secant line 110b along a direction PD perpendicular to the secant line 110b. Thus, the distances between points on the other part of the segment 118b above the secant line 110b (that is other part of the segment 118b other than the at least one part) and the projections of the points of the other part of the segment 118b projected on the secant line 110b (that are perpendicular distances between the segment 118b and the secant line 110b) may be calculated in the step S110A shown in FIG. 3, and the point with the largest distance from the secant line 110b is determined as the reference J point 112b, such that the reference J point 112b can be located.
FIG. 5C schematically illustrates a third example of a segmented ECG/EKG complex of the first geometry analysis mode. In some embodiments, as shown in FIG. 5C, when the whole segment 118c of the segmented ECG/EKG complex 100c between the reference S peak 104c and the reference T peak 106c is disposed under the secant line 110c, i.e. the amplitudes of all parts of the whole segment 118c are less than the amplitudes of parts of the secant line 110c corresponding to the segment 118c, the segmented ECG/EKG complex 100c is determined as a third example of the first geometry analysis mode, and the reference S peak 104c is determined as the reference J point 112c in the step S110A.
FIG. 6A schematically illustrates a first example of a segmented ECG/EKG complex of a second geometry analysis mode. As shown in FIG. 6A and FIG. 3, in the step SI 10B, when the amplitude of the reference S peak 104d is less than the amplitude of the reference baseline 108, and the amplitude of the reference T peak 106d is less than the amplitude of the reference baseline 108, the segmented ECG/EKG complex lOOd is determined as the second geometry analysis mode, and a secant line llOd passing through the reference S peak 104d and the reference T peak 106d can be obtained (indicated as a dotted line shown in FIG. 6 A). After that, the reference J point 112d is determined according to the second geometry analysis mode, the segmented ECG/EKG complex lOOd and the secant line llOd by geometry analysis. Specifically, the step S110B may further include firstly determining whether a slope of the secant line llOd is greater than 0 to obtain which example the segmented ECG/EKG complex lOOd is. When the slope of the secant line llOd is greater than 0, the segmented ECG/EKG complex lOOd is determined as the first example of the second geometry analysis mode. After the slope of the secant line llOd is determined, an amplitude of the segmented ECG/EKG complex lOOd is compared with an amplitude of the secant line llOd to determine whether an amplitude of at least one part of a segment 118d of the segmented ECG/EKG complex lOOd between the reference S peak 104d and the reference T peak 106d is greater than the amplitude of the secant line llOd. When the amplitude of at least one part of the segment 118d is greater than the amplitude of the secant line llOd, i.e. the at least one part of the segment 118d is disposed above the secant line llOd, the step of determining the reference J point 112d may include obtaining a point on the at least one part of the segment 118d that is farthest from the secant line llOd, and the point farthest from the secant line llOd may be determined as the reference J point 112d. The step of obtaining the point may include calculating minimum distances D between a plurality of points on the at least one part of the segment 118d and the secant line llOd, and the point determined as the reference J point 112d is the one of the points with largest one of the minimum distances D. For example, the minimum distances D between the points of the at least one part of the segment 118d and the secant line llOd may be obtained by calculating perpendicular distances between the points on the at least one part of the segment 118d and the secant line llOd. In detailed, distances between the points on the at least one part of the segment 118d and the projections of the points projected on the secant line llOd may be calculated, wherein the projections of the points are projected on the secant line llOd along a direction PD perpendicular to the secant line llOd. Thus, distances between the points on the at least one part of the segment 118d and the projections of the points projected on the secant line llOd (that are perpendicular distances between the segment 118d and the secant line l lOd) are calculated in the step S110B, and then, the point with the largest distance from the secant line llOd is determined as the reference J point 112d. Accordingly, the reference J point 112d can be located.
FIG. 6B schematically illustrates a second example of a segmented ECG/EKG complex of the second geometry analysis mode. In some embodiments, as shown in FIG. 6B, in the step S110B, when the slope of the segment 118e of the segmented ECG/EKG complex lOOe between the reference S peak 104e and the reference T peak 106e or the slope of the secant line llOe passing through the reference S peak 104e and the reference T peak 106e is negative or when the segment 118e coincides with the secant line llOe, the segmented ECG/EKG complex lOOe is determined as a second example of the second geometry analysis mode, and in such example, the reference S peak 104e is determined as the reference J point 112e.
As shown in FIG. 3, in the step 1 IOC and 110D, when the amplitude of the reference S peak is greater than the amplitude of the reference baseline, the reference S peak is determined as the reference J point. In detailed, please refer to FIG. 7A which schematically illustrates a first example of a segmented ECG/EKG complex of a third geometry analysis mode. As shown in FIG. 7A and FIG. 3, in the step SI IOC, when the amplitude of the reference S peak 104f is greater than the amplitude of the reference baseline 108 and the amplitude of the reference T peak 106f is greater than the amplitude of the reference baseline 108, the segmented ECG/EKG complex lOOf is determined as the third geometry analysis mode, and the reference S peak 104f is determined as the reference J point 112f. In the first example of the third geometry analysis mode shown in FIG. 7A, an amplitude of a medical S peak is greater than the amplitude of the reference baseline, the reference S peak 104f is the medical S peak, and the reference T peak 106f is the medical T peak, but not limited thereto.
FIG. 7B schematically illustrates a second example of a segmented ECG/EKG complex of a third geometry analysis mode. In some embodiments, the reference S peak 104g (that is S’ shown in FIG. 7B) may be different from the medical S peak 114 (that is S shown in FIG. 7B). As shown in FIG. 7B, the segmented ECG/EKG complex lOOg may have a medical S peak 114 different from the reference S peak 104g, and an amplitude of the medical S peak 114 is less than the amplitude of the reference baseline 108. In the step SI IOC, when the amplitude of the reference S peak 104g is greater than the amplitude of the reference baseline 108, the amplitude of the reference T peak 106g is greater than the amplitude of the reference baseline 108, and the reference S peak 104g is different from the medical S peak 114, the reference S peak 104g is also determined as the reference J point 112g. The segmented ECG/EKG complex lOOg may for example have rSr’ pattern in the second example of the third geometry analysis mode.
FIG. 8 schematically illustrates an example of a segmented ECG/EKG complex of a fourth geometry analysis mode. As shown in FIG. 8 and FIG. 3, in the step SHOD, when the amplitude of the reference S peak 104h is greater than the amplitude of the reference baseline 108, and the amplitude of the reference T peak 106h is less than the amplitude of the reference baseline 108, the segmented ECG/EKG complex lOOh is determined as the fourth geometry analysis mode, and the reference S peak 104h is determined as the reference J point 112h.
Refer to FIG. 3, through the J point locating process SI 14 mentioned above, the reference J point can be sought and located in the segmented ECG/EKG complex measured from the patient, thereby finding corresponding ST segment. Following the J point locating process SI 14, in the step SI 12, the information of reference J point may be sent or shown to the doctor, a patient, or AI data analytics. For example, the patient may be warned by the information to hospital, or the doctor may determine the symptom of the patient by the support of the information, such as determine whether voltage of the ST segment is greater than the standard of AHA (American Heart Association). Thus, the doctor or patient can be aware of whether the patient has STEMI as early as possible, or the doctor may be assisted to clinically diagnose the STEMI faster.
As the method for determining the J point mentioned above, the reference J point may be found according to signal of one lead instead of requiring all signals of 12 leads, and the reference J point can be easily found based on the determination of four geometry analysis modes with reduced calculation power such as mobile ECG/EKG device, so as to faster locating the reference J point and reduce
Door-to-Balloon time of patient at first place. Those skilled in the art will readily observe that numerous modifications and alterations of the device and method may be made while retaining the teachings of the disclosure. Accordingly, the above disclosure should be construed as limited only by the metes and bounds of the appended claims.

Claims

Claims What is claimed is:
1. A method for determining a J point of an electrocardiogram (ECG/EKG),
comprising:
providing an ECG/EKG complex;
providing a reference S peak, a reference T peak and a reference baseline of the ECG/EKG complex; and
performing a J point locating process of the ECG/EKG complex according to the reference S peak, the reference T peak and the reference baseline by a geometric analysis.
2. The method for determining the J point of the ECG/EKG according to claim 1, wherein the ECG/EKG complex is a segmented ECG/EKG complex.
3. The method for determining the J point of the ECG/EKG according to claim 2, wherein performing the J point locating process comprises determining a geometry analysis mode of the segmented ECG/EKG complex according to an amplitude of the reference S peak, an amplitude of the reference T peak and an amplitude of the reference baseline.
4. The method for determining the J point of the ECG/EKG according to claim 3, wherein performing the J point locating process further comprises determining a reference J point according to the geometry analysis mode, the segmented
ECG/EKG complex, and a secant line passing through the reference S peak and the reference T peak.
5. The method for determining the J point of the ECG/EKG according to claim 4, wherein determining the reference J point comprises comparing an amplitude of the segmented ECG/EKG complex with an amplitude of the secant line passing through the reference S peak and the reference T peak.
6. The method for determining the J point of the ECG/EKG according to claim 4, wherein the reference J point is determined according to a perpendicular distance between the segmented ECG/EKG complex and the secant line.
7. The method for determining the J point of the ECG/EKG according to claim 4, wherein determining the reference J point comprises determining whether a slope of the secant line is greater than 0.
8. The method for determining the J point of the ECG/EKG according to claim 4, wherein performing the J point locating process further comprises comparing the amplitude of the reference S peak with the amplitude of the reference baseline and comparing the amplitude of the reference T peak with the reference baseline.
9. The method for determining the J point of the ECG/EKG according to claim 8, wherein when the amplitude of the reference S peak is less than the amplitude of the reference baseline, and the amplitude of the reference T peak is greater than the amplitude of the reference baseline, performing the J point locating process further comprises comparing an amplitude of a segment of the segmented ECG/EKG complex between the reference S peak and the reference T peak with an amplitude of the secant line passing through the reference S peak and the reference T peak.
10. The method for determining the J point of the ECG/EKG according to claim 9, wherein when at least one part of the segment is disposed above the secant line, performing the J point locating process further comprises obtaining a point on the at least one part of the segment and farthest from the secant line, and the point is determined as the reference J point.
11. The method for determining the J point of the ECG/EKG according to claim 10, wherein obtaining the point comprising calculating minimum distances between a plurality of points on the at least one part of the segment and the secant line.
12. The method for determining the J point of the ECG/EKG according to claim 9, wherein when all the segment is disposed under the secant line, the reference S peak is determined as the reference J point.
13. The method for determining the J point of the ECG/EKG according to claim 8, wherein when the amplitude of the reference S peak is less than the amplitude of the reference baseline, and the amplitude of the reference T peak is less than the amplitude of the reference baseline, performing the J point locating process further comprises determining whether a slope of the secant line is greater than 0.
14. The method for determining the J point of the ECG/EKG according to claim 13, wherein when the slope of the secant line is greater than 0, and at least one part of a segment of the segmented ECG/EKG complex between the reference S peak and the reference T peak is disposed above the secant line, performing the J point locating process further comprises obtaining a point on the at least one part of the segment and farthest from the secant line, and the point is determined as the reference J point.
15. The method for determining the J point of the ECG/EKG according to claim 14, wherein obtaining the point comprising calculating minimum distances between a plurality of points on the at least one part of the segment and the secant line.
16. The method for determining the J point of the ECG/EKG according to claim 13, wherein when the slope of the secant line is negative, the reference S peak is determined as the reference J point.
17. The method for determining the J point of the ECG/EKG according to claim 8, wherein when the amplitude of the reference S peak is greater than the amplitude of the reference baseline, the reference S peak is determined as the reference J point.
18. The method for determining the J point of the ECG/EKG according to claim 17, wherein the amplitude of the reference T peak is greater than the amplitude of the reference baseline, an amplitude of a medical S peak is greater than the amplitude of the reference baseline, and the reference S peak is the medical S peak.
19. The method for determining the J point of the ECG/EKG according to claim 17, wherein the segmented ECG/EKG complex has a medical S peak different from the reference S peak, an amplitude of the medical S peak is less than the amplitude of the reference baseline, an amplitude of the medical S peak is less than the amplitude of the reference baseline, and the amplitude of the reference T peak is greater than the amplitude of the reference baseline.
20. The method for determining the J point of the ECG/EKG according to claim 8, wherein when the amplitude of the reference S peak is greater than the amplitude of the reference baseline, and the amplitude of the reference T peak is less than the amplitude of the reference baseline, the reference S peak is determined as the reference J point.
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