WO2020144495A1 - Film antimicrobien à destruction rapide - Google Patents

Film antimicrobien à destruction rapide Download PDF

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Publication number
WO2020144495A1
WO2020144495A1 PCT/IB2019/050251 IB2019050251W WO2020144495A1 WO 2020144495 A1 WO2020144495 A1 WO 2020144495A1 IB 2019050251 W IB2019050251 W IB 2019050251W WO 2020144495 A1 WO2020144495 A1 WO 2020144495A1
Authority
WO
WIPO (PCT)
Prior art keywords
antimicrobial
film
polymers
peg
eva
Prior art date
Application number
PCT/IB2019/050251
Other languages
English (en)
Inventor
Milad MEHRANPOUR
Seyedarmin SEYEDESFAHANI
Seyedali MOHAMMADI
Original Assignee
Mehranpour Milad
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mehranpour Milad filed Critical Mehranpour Milad
Priority to PCT/IB2019/050251 priority Critical patent/WO2020144495A1/fr
Priority to CA3092917A priority patent/CA3092917A1/fr
Publication of WO2020144495A1 publication Critical patent/WO2020144495A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
    • C09D7/40—Additives
    • C09D7/60—Additives non-macromolecular
    • C09D7/63—Additives non-macromolecular organic
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/14—Paints containing biocides, e.g. fungicides, insecticides or pesticides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0058—Biocides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/16—Nitrogen-containing compounds
    • C08K5/17—Amines; Quaternary ammonium compounds
    • C08K5/19—Quaternary ammonium compounds

Definitions

  • the technical field of this invention is related to medical, public healthcare products and health care facilities.
  • Antimicrobial coatings and films available on the market have a killing time over 24 hours. Therefore, they are not able to use in infected areas because they cannot kill bacteria and germs immediately.
  • Antimicrobial additives such as ethanol, isopropanol, chlorhexidine, propyl alcohol,
  • benzalkonium chloride peracetic acid, hydrogen peroxide, Didecyldimethylammonium chloride, Polyhexamethylene Biguanide Hydrochloride, chlorhexidine gluconate, alkyl dimethyl benzyl ammonium chloride, Sodium hypochlorite, iodine, 70% alcohol, glutaraldehyde, Sodium iodide and chloramine T, or a combination of these additives have immediate effect (under 24 hours) on bacteria. Usually these additives are used in gels and sprays and antiseptic tissues and so far these additives have not been used to produce antimicrobial films with self- antiseptics surface.
  • WO 2014/001541 is an invention related to an antimicrobial package suitable for containing materials which are susceptible to microbial growth or spoilage.
  • the invention relates to an antimicrobial package for food and drink products
  • WO 2006/000032 refers to an antimicrobial polymeric package in which an antimicrobial additive has been used.
  • This invention can be used in food packaging.
  • the polymeric materials are ethylene vinyl acetate (EVA), low-density polyethylene (PE), polyethylene glycol oil (PEG) and volatile antimicrobial oils.
  • the purpose of the invention is preventing the spread of bacteria and infectious disease by preparing a polymeric film with immediate bactericidal properties.
  • an antimicrobial agent is stored in a carrier which can regulate the antimicrobial agent release rate from an hour to several months.
  • the antimicrobial properties of the film produced in this invention are customizable.
  • This product can be used in the health-care facilities as smart coatings to prevent the transmission of microbes/ infections to every individual by direct and indirect contact. Moreover, it can be used as a smart covers in public areas and public transportation.
  • polymers such as ethylene -based polymers (high-density polyethylene (HDPE) , low density polyethylene (LDPE), linear low density polyethylene (LLDPE) ), polypropylene (PP), polyamide (PA), polystyrene (PS), Polyethylene terephthalate (PET), polyvinyl chloride (PVC), Ethylene vinyl acetate (EVA) (8%, 18%, 28%, 38%) and natural polymers such as starch, poly lactic acid (PLA), natural rubber (NR) and Acrylonitrile butadiene rubber (NBR), or a combination of one or more polymers by percentages 5% to 50% can be used for the preparation of the antimicrobial films.
  • HDPE high-density polyethylene
  • LDPE low density polyethylene
  • LLDPE linear low density polyethylene
  • PP polypropylene
  • PA polyamide
  • PS polystyrene
  • PET polyvinyl chloride
  • EVA Ethylene vinyl acetate
  • All films contain one or more carriers that hold antimicrobial agents, polymer’ s-compatible oils such as polyethylene glycol (PEG) with a molecular weight varies from 300 g / mole to 10,000,000 g / mole, Polypropylene glycol (PPG), Dioctyl phthalate (DOP), diisodecyl phthalate (DIDP), diisononyl phthalate (DINP) with a composition of 1% to 30%.
  • PEG polyethylene glycol
  • DOP Dioctyl phthalate
  • DIDP diisodecyl phthalate
  • DINP diisononyl phthalate
  • antimicrobial agents such as ethanol, isopropanol, chlorhexidine, propyl alcohol, benzalkonium chloride, peracetic acid, hydrogen peroxide, Didecyldimethylammonium chloride, Polyhexamethylene Biguanide Hydrochloride, chlorhexidine gluconate, alkyl dimethyl benzyl ammonium chloride, Sodium hypochlorite, iodine, 70% alcohol, glutaraldehyde, Sodium iodide and chloramine T, with the composition of 0.01% to 20% can be used. Based on the type of the polymer oil and antimicrobial agents, the effective film performance time range can be tuned.
  • the polymers that were used to prepare the films for this invention were LLDPE / EVA/ Oil with the volume fraction of (70%/28%/2%), respectively.
  • the combination of PEG 400 and 4000 with the volume fraction of 50%/50% were used as an antimicrobial carrier and benzalkonium chloride was used as antimicrobial agent with the volume fraction of 0.13%.
  • E.coli bacteria with the concentration of 106 x 1.5 CFU / ml was prepared. 100 m ⁇ of fluid was contacted for 24 hours before inoculation with the sample. After culturing the medium for 8 hours, according to the optical density method, each sample series was evaluated using three biological replications at 600 nm wavelength. The results of microbial tests taken at different time intervals from films prepared with different composition percentages showed that 98.9% of bacteria were killed.
  • the film produced in this invention can be used in disposable and multi-use applications in various industries and locations.
  • the user should choose the appropriate film based on the sensitivity of the desired location.
  • the user based on the type of film, the user must, at the beginning of each shift (or based on the time period written on the film) , according to different places, the consumer should covers the desired location and then depending on the determined time collects the film covers and replaced them with the new covers (according to the place the films are consumed, they can be in the different forms such as rolled-films, pre-shaped films, shrink films and etc.)
  • the film in the hospital, can be stretched over on the seating chairs in waiting rooms, beds, hospitals equipment that are frequently touched by patients, , nurses, doctors, medical specialists and health care facilities, etc. It can be used in public transportation, for example, subway and bus handles and escalator handles. In educational centers, for example, it can be wrapped up in a kindergarten on a children's playground, on children's play toys such as chute, swings and so on.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Plant Pathology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne la prévention de la propagation de bactéries et d'une maladie infectieuse par préparation d'un film polymère présentant des propriétés bactéricides immédiates. Dans la présente invention, l'agent antimicrobien est stocké dans un support qui peut réguler la vitesse de libération de l'agent antimicrobien, d'une heure à plusieurs mois. Il convient d'observer que les propriétés antimicrobiennes du film produit par la présente invention sont personnalisables. Ce produit peut être utilisé dans des établissements de santé sous forme de revêtements intelligents, afin de prévenir la transmission de microbes/d'infections à chaque individu par contact direct et indirect. De plus, il peut être utilisé en tant que bâches intelligentes dans les zones recevant du public et le transport public.
PCT/IB2019/050251 2019-01-13 2019-01-13 Film antimicrobien à destruction rapide WO2020144495A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/IB2019/050251 WO2020144495A1 (fr) 2019-01-13 2019-01-13 Film antimicrobien à destruction rapide
CA3092917A CA3092917A1 (fr) 2019-01-13 2019-01-13 Film antimicrobien a destruction rapide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2019/050251 WO2020144495A1 (fr) 2019-01-13 2019-01-13 Film antimicrobien à destruction rapide

Publications (1)

Publication Number Publication Date
WO2020144495A1 true WO2020144495A1 (fr) 2020-07-16

Family

ID=71520921

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2019/050251 WO2020144495A1 (fr) 2019-01-13 2019-01-13 Film antimicrobien à destruction rapide

Country Status (2)

Country Link
CA (1) CA3092917A1 (fr)
WO (1) WO2020144495A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1773130A1 (fr) * 2004-06-29 2007-04-18 Victoria University Of Technology Materiau d'emballage anti-microbien
JP2013523992A (ja) * 2010-04-14 2013-06-17 エーブリー デニソン コーポレイション ポリマーフィルムにおいて抗菌剤の有効性を向上させる方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1773130A1 (fr) * 2004-06-29 2007-04-18 Victoria University Of Technology Materiau d'emballage anti-microbien
JP2013523992A (ja) * 2010-04-14 2013-06-17 エーブリー デニソン コーポレイション ポリマーフィルムにおいて抗菌剤の有効性を向上させる方法

Also Published As

Publication number Publication date
CA3092917A1 (fr) 2020-07-16

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