WO2020108547A1 - Intravascular stent and embedded branch stent thereof - Google Patents

Intravascular stent and embedded branch stent thereof Download PDF

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Publication number
WO2020108547A1
WO2020108547A1 PCT/CN2019/121440 CN2019121440W WO2020108547A1 WO 2020108547 A1 WO2020108547 A1 WO 2020108547A1 CN 2019121440 W CN2019121440 W CN 2019121440W WO 2020108547 A1 WO2020108547 A1 WO 2020108547A1
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WO
WIPO (PCT)
Prior art keywords
branch
main body
tube
line branch
window
Prior art date
Application number
PCT/CN2019/121440
Other languages
French (fr)
Chinese (zh)
Inventor
王永胜
李安伟
尹玉杨
Original Assignee
杭州唯强医疗科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201821980894.5U external-priority patent/CN209827101U/en
Priority claimed from CN201811449123.8A external-priority patent/CN111227991A/en
Application filed by 杭州唯强医疗科技有限公司 filed Critical 杭州唯强医疗科技有限公司
Publication of WO2020108547A1 publication Critical patent/WO2020108547A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents

Definitions

  • the present application relates to the technical field of implantable blood vessels, in particular to a blood vessel stent with an embedded branch stent, and an embedded branch stent of the blood vessel stent.
  • Aortic aneurysm refers to the local or diffuse abnormal expansion of the aortic wall, which causes symptoms by compressing the surrounding organs. Aneurysm rupture is the main risk. It often occurs in the ascending aortic aortic arch, thoracic descending aorta, thoracic and abdominal aorta, and abdominal aorta. According to the structure, aortic aneurysms can be divided into true aortic aneurysms and false aortic aneurysms. Aortic aneurysms cause an increase in the medial pressure of the blood vessels, so they are progressively enlarged.
  • Aortic dissection is another serious aortic disease.
  • Aortic dissection refers to the destruction of the media of the thoracic aorta, bleeding within the blood vessel wall, and blood entering between the media and the adventitia of the blood vessel wall. Due to the impact of blood flow, once the aortic dissection is formed, the tear can be extended in the direction of blood flow, the dissection and the false cavity can be enlarged, and the true cavity can be compressed. Therefore, the possible risks of patients with aortic dissection include: (1) the threat of complete rupture of the blood vessel. Once the blood vessel is completely ruptured, the mortality rate is extremely high; (2) the dissection gradually expands and compresses the true cavity to supply blood to the distal end cut back.
  • aortic dissection secondary to the thoracic aortic aneurysm, or coexist with the aortic aneurysm.
  • the British Oxford Vascular Disease Study shows that the incidence of aortic dissection in natural population is about 6/100,000 per year, with more men than women, with an average age of 63 years. The incidence of aortic dissection in my country is much higher than that in European and American countries, and the age of onset is relatively young.
  • Aortic aneurysm diseases may involve branched arteries. Once the branched artery is involved, it will be difficult to resolve through interventional methods.
  • arterial cavity treatment has been carried out at home and abroad, that is, a minimally invasive method is used to implant arterial grafts into the diseased artery through the vascular channel to treat arterial disease and improve blood supply, so as to achieve the purpose of treatment.
  • the endoluminal artery stent graft is composed of a tubular rigid wire stent and an artificial blood vessel fixed on the outside of the stent.
  • the tubular rigid wire stent is formed of a flexible rigid wire that is folded in a Z shape to form a ring.
  • a ring-shaped rigid wire and artificial blood vessel are sutured or bonded together to form a tubular stent graft.
  • the tubular stent graft When in use, the tubular stent graft is compressed axially and loaded into the conveyor, which is delivered to the diseased artery through the smaller femoral artery, iliac artery, and brachial artery and then released due to the elastic force of the wire stent The effect is automatically restored to a straight tube and closely adheres to the inner wall of the aorta, isolating the artery lesion from the blood flow, thereby achieving the purpose of treatment.
  • stents related to arterial branch therapy include chimney stents, integrated multi-branch stents, and window-type stents. These stents are limited by the structure of the stent and often need to be customized temporarily, especially for some connection angles are relatively small
  • the branch stent When the branch stent is connected to the main vessel and the branch vessel, the branch stent often has a large bending angle, which causes the branch stent to be squeezed by the main stent and become blocked.
  • the purpose of the present application is to provide an in-line branch stent capable of preventing endoleak, and a blood vessel stent provided with the in-line branch stent.
  • an in-line branching bracket which includes a main body tube, and the main body tube includes a main body covering film, at least one window is opened on the main body covering film, and the in-line branching support It also includes at least one in-line branch tube disposed in the inner cavity of the main body tube, at least one in-line branch tube extending from at least one window opening toward the inner cavity of the main body tube, the in-line branch tube The angle between the axis of and the axis of the main body tube is greater than 0 degrees.
  • the present application also provides a vascular stent including an in-line branch stent and at least one branch tube.
  • the in-line branch stent includes a main body tube, and the main body tube includes a main body membrane, and the main body membrane is provided with at least one A window opening
  • the in-line branch bracket further includes at least one in-line branch tube disposed in an inner cavity of the main body tube, at least one in-line branch tube from at least one of the window opening toward the main body tube
  • the inner cavity extends, and the angle between the axis of the embedded branch tube and the axis of the main body tube is greater than 0 degrees, and the proximal end of the branch tube is inserted into the inline branch support through the window opening Inside the branch pipe.
  • the embedded branch stent of the vascular stent includes a main body tube and at least one branch tube disposed in the lumen of the main body tube, an angle between the axis of the embedded branch tube and the axis of the main body tube is greater than 0 degrees .
  • the branch tube is obliquely connected to the main body tube, which can prevent the branch tube from being released into the branch blood vessel Afterwards, the branch pipe is prevented from being blocked due to bending caused by being squeezed due to excessive bending at the connection with the main body pipe.
  • FIG. 1 is a schematic structural diagram of a vascular stent provided in the first embodiment of the present application.
  • FIG. 2 is a schematic structural diagram of the in-line branch bracket in FIG. 1.
  • FIG. 3 is a schematic perspective view of the ring-shaped wave supporting rod in FIG. 2.
  • FIG. 4 is a schematic view of the structure of the ring-shaped wave supporting rod in FIG. 1 connected to the main body film.
  • 5a-5c are structural schematic diagrams of other forms of an embedded branch tube with an embedded branch bracket of the present application.
  • FIG. 6 is an enlarged view of the proximal end portion of the in-line branch stent in FIG. 1.
  • FIG. 7a and 7b are schematic diagrams of different development structures around the window of the embedded branching bracket of the present application.
  • FIG. 8 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a second embodiment of the present application.
  • FIG. 9 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a third embodiment of the present application.
  • FIG. 10 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a fourth embodiment of the present application.
  • proximal end in the present application refers to the end close to the position of the heart
  • distal end refers to the end far from the position of the heart.
  • high and low mentioned in this application are relative to the body tube coating.
  • the end surface that exceeds the body tube coating is called high, and the one that does not exceed the body tube coating is called low. This definition is just for convenience of expression, and It cannot be understood as a limitation of this application.
  • FIG. 1 is a schematic structural diagram of a vascular stent provided in a first embodiment of the present application.
  • the present application provides a vascular stent 100 including an embedded branch stent 20 and at least one branch tube 40.
  • the in-line branching bracket 20 includes a main body tube 21 and at least one in-line branching tube 25.
  • the main body tube 21 is of an equal-diameter structure or a non-equi-diameter structure.
  • the main body tube 21 includes a tubular main body film 210, and at least one of the embedded branch tubes 25 is disposed in the inner cavity of the main body tube 21 of the embedded branch bracket 20.
  • At least one window 211 is provided on the main body film 210, and at least one embedded branch tube 25 extends from the at least one window 211 toward the inner cavity of the main body tube 21.
  • the angle between the axis of the embedded branch pipe 25 and the axis of the main body pipe 21 is greater than 0 degrees.
  • the proximal end of the branch pipe 40 is inserted into the inner cavity of the embedded branch pipe 25 of the embedded branch bracket 20 through the window 211, and the branch pipe 40 is hermetically sleeved with the embedded branch pipe 25 The near end.
  • the main body tube 21 has a non-equal-diameter structure.
  • the proximal end diameter of the main body pipe 21 is larger than the distal end diameter, and the diameter of the main body pipe 21 tapers from the proximal end to the distal end.
  • the main body coating 210 is a tubular structure, and the shape of the lateral end surface is a circle, an ellipse, or a prism that matches the blood vessel. At least one of the window openings 211 is opened on the tubular film.
  • the window openings 211 may be circular holes, elliptical holes, prismatic holes, or irregular curved surfaces.
  • the main body film 210 is made of polyester cloth, PTFE, PET or other polymer materials.
  • the embedded branch stent 20 and the branch tube 40 are both self-expanding stents.
  • the embedded branch stent 20 or the branch tube 40 When the embedded branch stent 20 or the branch tube 40 is delivered through the sheath tube, the embedded branch stent 20 or the branch The diameter of the tube 40 can be reduced to a smaller state for delivery in the sheath; when the embedded branch stent 20 or the branch tube 40 is released in the blood vessel, the embedded branch stent 20 or the branch tube 40 It can be automatically expanded to the required shape and size, so that the embedded branch stent 20 or the branch tube 40 can be supported on the inner wall of the vascular lesion, and the embedded branch stent 20 or the branch tube 40 The inner wall of the blood vessel produces radial support, which can rebuild the blood vessel.
  • the embedded branch stent 20 of the vascular stent 100 of the present application includes a main body tube 21 and at least one branch tube 40 disposed in the lumen of the main body tube 21, the axis of the embedded branch tube 25 and the axis of the main body tube 21 The angle between is greater than 0 degrees.
  • the branch tube 40 needs to be connected to the embedded branch bracket 20, insert the proximal end of the branch tube 40 into the inner cavity of the embedded branch tube 25, the embedded branch tube 25 can be sealed
  • the outer peripheral surface of the proximal end of the branch tube 40 is wrapped, so as to effectively prevent the internal leakage of the connection position of the branch tube 40 and the embedded branch bracket 20, and facilitate the insertion of the branch tube 40 on the embedded branch bracket 20.
  • the branch pipe 40 is obliquely connected to the main body pipe 21, which prevents the branch pipe 40 from After being released to the branch blood vessel, it is bent due to being squeezed due to excessive bending amplitude, thereby preventing the branch tube 40 from being blocked.
  • the angle between the axis of the inline branch pipe 25 and the axis of the main body pipe 21 is a value within a range of 5 degrees, 45 degrees, or 5 degrees to 45 degrees.
  • the embedded branch pipe 25 is obliquely connected to the main body pipe 21, that is, the axis of the embedded branch pipe 25 and the main body pipe
  • the angle between the axes of 21 is a value in the range of 5 degrees, 45 degrees, or 5 degrees to 45 degrees.
  • the axis of the proximal end of the branch pipe 40 coincides with the axis of the embedded branch pipe 25, so that the branch pipe 40 It is connected to the main body tube 21 obliquely.
  • the angle between the axis of the inline branch pipe 25 and the axis of the main body pipe 21 can be selected according to need.
  • the axial extension length of the embedded branch pipe 25 is greater than or equal to 2 mm.
  • the axial extension length of the embedded branch pipe 25 is a value in the range of 2 mm, 100 mm, or 2 mm to 100 mm.
  • the inner diameter of the embedded branch pipe 25 is greater than or equal to 2 mm.
  • the inner diameter of the embedded branch pipe is a value in the range of 2 mm, 5 mm, or 2 mm to 5 mm.
  • the embedded branch pipe 25 serves as an anchor portion for connecting between the main body pipe 21 and the branch pipe 40.
  • FIG. 2 is a schematic structural view of the in-line branch support in FIG. 1;
  • FIG. 3 is a perspective structural schematic view of the annular wave-shaped support rod in FIG. 2;
  • FIG. Schematic diagram of the structure of the corrugated support rod connected to the main body film.
  • the main body tube 21 further includes a main body support frame 212 provided on the inner or outer circumferential surface of the main body film 210. Specifically, the main body support frame 212 is sewn to the main body film 210 by a suture. Inner peripheral surface or outer peripheral surface.
  • the main body supporting framework 212 may be an elastic metal supporting framework or an elastic non-metallic supporting framework such as a polymer material.
  • the main body supporting framework 212 is a nickel alloy stent.
  • the diameter of the main body supporting framework 212 may be contracted to a smaller state for transport in the sheath; when When the main body supporting framework 212 is released in the blood vessel, the main body supporting framework 212 can automatically expand to the desired shape and size, so that the main body supporting framework 212 can be supported on the inner wall of the corresponding blood vessel.
  • the main body supporting framework 212 may be laser-cut with a nickel alloy tube, or may be woven with metal wires such as nickel alloy wires.
  • the degree of density of the mesh structure of the main body supporting skeleton 212 is set as required.
  • the main body support frame 212 includes a plurality of Z-shaped or sinusoidal wave-shaped support rods 2120, and these ring-shaped support rods 2120 are arranged at intervals along the axial direction of the main body coating 210, that is, these rings
  • the wave-shaped support rods 2120 are arranged in parallel with a gap from the proximal end to the distal end of the main body tube 21.
  • Each ring-shaped wave support bar 2120 may be a high-wave wave support bar or a high-low wave support bar, etc.
  • the contour wave support bar means that the height of each wave peak on the ring-shaped wave support bar 2120 is the same, and the height of each wave valley is the same That is, the peaks and troughs are on the same plane.
  • the high and low wave support bars mean that the heights of at least two wave peaks on the ring-shaped wave support bar 2120 are different, and/or the heights of at least two wave troughs are different.
  • the annular wave-shaped support rods 2120 of the main body tube 21 are all constant-wave support rods.
  • each Z-shaped or sinusoidal waveform of each annular waveform support rod 2120 includes a peak 2121, a valley 2123, and a connecting rod 2125 connected between the peak 2121 and the valley 2123 .
  • Each annular wave-shaped support rod 2120 is woven by a super-elastic nickel-titanium wire, and the selectable wire diameter (ie diameter) of the super-elastic nickel-titanium alloy wire is 0.2 mm to 0.55 mm.
  • Each annular wave-shaped support rod 2120 is provided with a connection sleeve 2127 for connecting opposite ends of the superelastic nickel-titanium wire to form an annular wave-shaped support rod 2120, that is, superelastic Both ends of the nickel-titanium wire are accommodated in the connecting sleeve 2127, and then the two ends of the nickel-titanium wire are fixed inside the connecting sleeve 2127 by mechanical compression or welding.
  • the annular wave-shaped support rod 2120 is braided with 0.4 mm diameter nickel-titanium wire, the number of Z-shaped or sinusoidal waves is 9, and the vertical height of the annular wave-shaped support rod 2120 is 8-15 mm.
  • the main body supporting skeleton 212 may be a woven mesh structure or a cut mesh structure.
  • the number of sine waves of the annular wave-shaped support rod 2120 may be determined according to needs, and the vertical height of the annular wave-shaped support rod 2120 may be any height.
  • each ring-shaped wave support rod 2120 of the main body support frame 212 is sewn to the body film 210 by a suture 23, that is, the thread 23 can be along each ring-shaped wave support rod
  • the wave shape of 2120 is accompanied by the entire main body supporting skeleton 212.
  • the suture 23 can also be sutured to the main body covering film 210 by a plurality of unequally spaced stitching knots.
  • the selection range of the diameter of the suture 23 is 0.05mm-0.25mm.
  • the main body support frame 212 may be fixedly connected to the main body film 210 by hot pressing.
  • a transition film 251 is connected between the embedded branch pipe 25 and the window 211, and the transition film 251 is tubular or conical ring-shaped, and the shape of its lateral end surface and the shape of the window 211 Correspondingly, it can be circular, elliptical or prismatic.
  • the transition film 251 extends from the window 211 toward the inner cavity of the main body tube 21.
  • One end of the transition film 251 is hermetically connected to the edge of the window 211, and the other end of the transition film 251 is hermetically connected to the proximal end of the embedded branch tube 25.
  • the edge of the proximal end of the transition film 251 is sealingly connected to the edge of the main body film 210 at the window 211, and the edge of the distal end of the transition film 251 is sealingly connected to the inlay
  • the outer diameter of the proximal end of the transition coating 251 is greater than the outer diameter of the distal end.
  • the transition film 251 is made of polyester cloth, PTFE, PET or other polymer materials.
  • the transitional film 251 Since the transitional film 251 is connected between the embedded branch pipe 25 and the window 211, the transitional film 251 can be sealingly connected between the main body film 210 and the embedded branch pipe 25, therefore, the The transition film 251 can prevent internal leakage between the embedded branch pipe 25 and the window 211.
  • the outer diameter of the distal end of the transition coating 251 is greater than the outer diameter of the proximal end, so that the transition coating forms an inner recess, and the inner recess has a guiding effect.
  • the cross-section of the distal end of the transition film 251 is recessed inward relative to the window opening to form a guide portion, so that the connection of the branch pipe 40 and the embedded branch pipe 25 is smoother.
  • the proximal end of the transition film 251 is stitched to the main body film 210 at the edge of the window 211 by a suture, and the distal end of the transition film 251 is stitched to the inside by a stitch
  • the proximal end of the branch tube 25 is embedded.
  • the distal end of the transition membrane 251 may be an integral structure with the proximal end of the embedded branch tube 25.
  • connection between the proximal end of the transition coating 251 and the main body coating 210 may be connected by medical glue, and the distal end of the transition coating 251 and the embedded branch tube 25
  • the connection can also be via medical glue.
  • a support skeleton may be provided on the transition coating 251 to stretch the transition coating 251.
  • the support frame may be stitched to the inner peripheral surface or the outer peripheral surface of the transition coating 251 by a suture.
  • the embedded branch pipe 25 includes a tubular shaped embedded branch coating 253 and a support frame 255 provided on the embedded branch coating 253, that is, the inner or outer peripheral surfaces of the support frame 255 are bonded together There is the embedded branch film 253.
  • the support frame 255 is fixed between the inner peripheral surface or the outer peripheral surface of the embedded branch coating 253 or the multilayer coating by means of stitching or hot pressing.
  • the shape of the lateral end surface of the embedded branch coating 253 is a circle, an ellipse, or a prism matching the proximal end of the branch tube 40.
  • the proximal end of the embedded branch coating 253 is connected to the transition coating 251. remote.
  • the distal end of the embedded branch membrane 253 extends toward the inner cavity of the main body tube 21. In the extended state, the angle between the axis of the embedded branch film 253 and the axis of the main body tube 21 is greater than 0 degrees.
  • the main body film 210 is made of polyester cloth, PTFE, PET or
  • the supporting framework 255 may be an elastic metal supporting framework or an elastic non-metallic supporting framework such as a polymer material.
  • the support frame 255 is a nickel alloy stent.
  • the diameter of the support frame 255 can be contracted to a smaller state for transportation in the sheath tube; when the support frame When 255 is released, the support frame 255 can automatically expand to the desired shape and size.
  • the support frame 255 can support the embedded branch coating film 253 to keep the embedded branch coating film 253 in an open state, which is convenient for the connection of the branch tube 40.
  • the support frame 255 may be laser-cut with a nickel alloy tube, or may be woven with metal wires such as nickel alloy wires.
  • the degree of density of the mesh structure supporting the skeleton 255 is set as required.
  • the support frame 255 includes a plurality of Z-shaped or sinusoidal ring-shaped wave-shaped support rods, and these ring-shaped wave-shaped support rods are arranged at intervals along the axial direction of the embedded branch coating 253, that is, these ring-shaped support rods
  • the wave-shaped support rods are arranged in parallel gaps from the proximal end to the distal end of the embedded branch covering film 253 in sequence.
  • the inner diameter of the embedded branch tube 25 is less than or equal to the outer diameter of the proximal end of the branch tube 40.
  • FIG. 5a to FIG. 5c are schematic structural diagrams of other forms of the embedded branch tube with the embedded branch bracket of the present application.
  • the support frame 255 of the embedded branch pipe 25 can be selected from any ring-shaped support frame as shown in FIGS. 5a and 5b or the mesh frame shown in FIG. 5c.
  • the ring-shaped support frame includes a number of Z-shaped or sinusoidal wave-shaped ring-shaped support rods, which are arranged at intervals along the axial direction of the embedded branch pipe 25.
  • the mesh skeleton may be woven or cut.
  • the embedded branch tube 25 includes only the embedded branch coating 253, that is, the supporting frame 255 on the embedded branch coating 253 can be omitted, and the proximal end of the embedded branch coating 253 is connected to the transition coating The distal end of the membrane 251.
  • the embedded branch pipe 25 only includes a support frame 255, that is, the embedded branch film 253 on the support frame 255 may be omitted, the support frame 255 is a bare support, and the bare support may be a braid Or cut the bare bracket of the structure.
  • the proximal end of the bare stent is connected to the distal end of the transition membrane 251.
  • the in-line branch tube 25 includes an in-line branch film 253 directly connected to the window 211.
  • the in-line branch film 253 and the main body film 210 are adjacent to the window 211.
  • the embedded branch film 253 is used to wrap the proximal end of the branch tube 40.
  • the transition film 251 between the embedded branch tube 25 and the window 211 may be omitted, but directly connected to the main body film through the proximal end of the embedded branch film 253 directly and sealingly 210 at the edge of the window 211.
  • the embedded branch coating film 253 has a tubular structure, and the shape of the lateral end surface of the embedded branch coating film 253 is consistent with the shape of the window 211, and is specifically circular, elliptical, or prismatic.
  • the embedded branch coating film 253 may be provided with an elastic embedded branch skeleton, and the embedded branch skeleton is attached to the inner peripheral surface or the outer peripheral surface of the embedded branch coating film 253.
  • the embedded branch skeleton can make the connection of the branch pipe 40 connected in the embedded branch pipe 25 firmer, and can maintain the shape of the branch pipe 40 entering the embedded branch pipe 25.
  • the embedded branch skeleton on the embedded branch coating 253 may also be omitted.
  • a support member 214 is provided at the edge of the window opening 211, and the support member 214 is used to support the window opening 211 to keep the window opening 211 open.
  • the support member 214 is a support rod fixed to the edge of the window opening 211, the support rod extends along the edge of the window opening 211, the support rod adapts to the shape of the edge of the window opening 211, specifically,
  • the support rod may have a circular, elliptical or prismatic ring structure.
  • the support member 214 is a support ring extending along the edge of the window 211, and the support ring has elasticity.
  • the support ring can be closely attached to the outer surface of the branch pipe 40 to prevent internal leakage at the junction of the branch pipe 40 and the main body pipe 21.
  • the support 214 is made of memory alloy, preferably nickel-titanium alloy.
  • the main body film 210 is provided with a developing structure 215 around the window 211.
  • the developing structure 215 is provided on the main body film 210 continuously or along the edge of the window 211.
  • Multiple development points arranged intermittently. These developing points can be fixed on the main body cover film 210 by sewing, stamping, setting or sticking. These developing points are arranged at least once along the peripheral edges of the window 211.
  • the material of the developing structure 215 may be made of a material with good X-ray opacity, strong corrosion resistance and good biocompatibility.
  • the developing member include, but are not limited to, gold, platinum, tantalum, osmium, rhenium, tungsten, iridium, rhodium and other materials or alloys or composites of these metals.
  • the developing point is a nickel-titanium alloy metal sheet containing tantalum. The ring formed by these developing points is consistent with the shape of the window 211. Therefore, these developing points form a connected or intermittent ring-shaped developing mechanism.
  • the position of the developing structure 215 can be clearly observed by the imaging device, that is, It can be observed that the developing point near the window opening 211 is a ring-shaped developing mechanism around the edge of the window opening 211, therefore, it is more convenient and quick to insert the branch tube 40 in the embedded branch tube 25 The near end.
  • the developing structure 215 is a developing wire wound continuously or intermittently on the support member 214.
  • the developing wire may be a nickel-titanium alloy wire containing tantalum, and the diameter of the nickel-titanium alloy wire is 0.10-0.40 mm. Since the developing structure 215 is developable and ring-shaped, the position of the developing structure 215 can be clearly observed through the imaging device during the operation, that is, the developing structure 215 can be observed around the edge of the window 211 The surrounding annular developing structure is not a scattered developing point. Therefore, it is more convenient and quick to insert the branch pipe 25 into the branch pipe 40.
  • the developing structure 215 is a developing point that is continuously or intermittently fixed on the supporting member 214, and the developing point is stitched, stamped, hot-pressed, set or pasted. It is fixed on the support 214. These developing points are arranged at least once around the supporting member 214.
  • the supporting member 214 is made of an alloy mixed with a developing material, and the developing structure 215 is a developing material fused into the supporting member 214.
  • the support member 214 is surrounded by a nickel-titanium alloy wire containing tantalum, and the wire diameter of the support member 214 is 0.10-0.40 mm. Since the supporting member 214 is made of an alloy containing a developing material, the supporting member 214 can be directly used as a developing structure, and no additional developing structure needs to be provided on the supporting member 214. During the operation, the position of the support 214 can be clearly observed through the imaging equipment, and the branch tube 40 can be inserted into the window 211 conveniently and quickly, which is convenient to use.
  • the outer surface of the support member 214 may be inlaid with a nickel titanium alloy wire for at least one week, or the outer surface of the support member 214 may be pasted with a nickel nickel alloy wire for at least one week.
  • tantalum wire is wound on the support 214.
  • FIG. 8 is a schematic structural diagram of an in-line branch support provided by a second embodiment of the present application.
  • the structure of the embedded branch stent provided in the second embodiment of the present application is similar to the structure of the first embodiment, except that in the second embodiment, the proximal end and/or the distal end of the embedded branch tube 25
  • a support ring 256 is provided at the nozzle of the tube, and the support ring 256 is used to expand the embedded branch coating 253, so that the embedded branch coating 253 can be kept in an unfolded state to facilitate insertion of the branch tube 40.
  • the support ring 256 extends along the edge of the opening at the proximal end or the distal end of the embedded branch film 253, and the support ring 256 adapts to the edge shape of the cross section of the embedded branch tube 25.
  • the support The ring 256 may be circular, elliptical or prismatic.
  • the support ring 256 has elasticity. When the branch pipe 40 needs to be connected in the window 211, the support ring 256 can be closely attached to the outer surface of the branch pipe 40 to prevent the branch pipe 40 from connecting with the embedded branch pipe 25 An internal leak occurred.
  • the support ring 256 is made of memory alloy, preferably nickel titanium alloy.
  • a ring-shaped developing portion is provided at the proximal end and/or the distal end of the embedded branch tube 25, and the ring-shaped developing portion is disposed at least once around the circumference of the embedded branch tube 25.
  • the ring-shaped developing part may be provided at the edge of the opening of the proximal end and/or the distal end of the in-line branching film 253, and the ring-shaped developing part may also be a support ring provided in the inline branching tube 25 256.
  • the ring-shaped developing portion is provided on the support ring 256 and includes but is not limited to the following: a development wire, such as a nickel-titanium alloy wire containing tantalum and a nickel-titanium wire, is connected or intermittently wound on each support ring 256
  • the diameter of the alloy wire is 0.10-0.40mm; the developing wire on the support ring 256 has developability and is ring-shaped, thereby forming a ring-shaped developing portion; the support ring 256 can be clearly observed by the imaging device during the operation
  • the position of the developing wire can be inserted into the branch pipe 40 in the embedded branch pipe 25 conveniently and quickly.
  • each supporting ring 256 may also be made of an alloy doped with a developing material, for example, a nickel-titanium alloy wire containing tantalum, so that the supporting ring 256 itself forms an annular developing portion.
  • FIG. 9 is a schematic structural diagram of an in-line branch bracket provided in a third embodiment of the present application.
  • the structure of the embedded branch bracket provided in the third embodiment of the present application is similar to the structure of the first embodiment, except that in the third embodiment, the main body support frame 212 of the main body tube 21 is located on the window 211 A support portion 2122 with a small waveform is provided at the proximal end and/or the distal end, and the support portion 2122 is used to better prop up the window 211.
  • the support portion 2122 is disposed on the crest and/or trough of the annular wave-shaped support rod 2120 adjacent to the window opening 211, so that the support portion 2122 is located at the proximal end and/or far away of the window opening 211 end.
  • the support portion 2122 includes a trough 2124 adjacent to the edge of the window 211, connecting rods 2128 at opposite ends of the trough 2124, and A wave peak 2126 connected to an end of each connecting rod 2128 away from the trough 2124 and connected to the connecting rod 2125 of the corresponding annular waveform support rod 2120.
  • the support portion 2122 can better support the window 211, thereby reducing the deformation of the window 211, It is convenient to insert the branch pipe 40 in the window 211.
  • FIG. 10 is a schematic structural diagram of an embedded branch stent of a vascular stent provided in a fourth embodiment of the present application.
  • the structure of the in-line branch bracket provided by the fourth embodiment of the present application is similar to the structure of the third embodiment, except that in the fourth embodiment, the main body support frame 212 of the main body pipe 21 is located at the window 211 A supporting portion with a small waveform is also provided at the distal end, and the supporting portion is disposed on the wave valley of the annular waveform supporting rod 2120 adjacent to the window 211.
  • the support portion includes a peak 2126a adjacent to the far edge of the window 211, connecting rods 2128a located at opposite ends of the peak 2126a, and an end connected to each connecting rod 2128a away from the peak 2126a and corresponding to
  • the trough 2124a is connected to the connecting rod 2125 of the annular wave-shaped support rod 2120. Since the wave crest 2126a and the two wave troughs 2124a are both adjacent to the window opening 211, the supporting portion can better support the window opening 211 and reduce the deformation of the window opening 211.

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Abstract

Provided is an intravascular stent (100), comprising an embedded branch stent (20), and at least one branch tube (40). The embedded branch stent (20) comprises a main body tube (21), the main body tube (21) comprises a main body coating (210), and at least one window (211) is provided in the main body coating (210). The embedded branch stent (20) further comprises at least one embedded branch tube (25) arranged in an inner cavity of the main body tube (21), and at least one embedded branch tube (25) extends toward the inner cavity of the main body tube (21) from the at least one window (211). The angle between the axis of the embedded branch tube (25) and the axis of the main body tube (21) is greater than 0 degrees. A proximal end of the branch tube (40) penetrates through the window (211) and is inserted into the embedded branch tube (25) of the embedded branch stent (20).

Description

血管支架及其内嵌分支支架Vascular stent and its embedded branch stent 技术领域Technical field
本申请涉及可植入血管技术领域,尤其涉及一种具有内嵌分支支架的血管支架,以及所述血管支架的内嵌分支支架。The present application relates to the technical field of implantable blood vessels, in particular to a blood vessel stent with an embedded branch stent, and an embedded branch stent of the blood vessel stent.
背景技术Background technique
主动脉瘤是指主动脉壁局部或弥漫性的异常扩张,压迫周围器官而引起症状,瘤状破裂为其主要危险。常发生在升主动脉主动脉弓、胸部降主动脉、胸腹主动脉和腹主动脉。主动脉瘤按结构可分为真性主动脉瘤和假性主动脉瘤。主动脉瘤引起血管内侧压增高,故呈进行性膨大,若长期发展,最后终归破裂,瘤体越大,破裂的可能性越大。据统计,若不作手术治疗,90%胸主动脉瘤在5年内死亡,3/4腹主动脉瘤在5年内死亡。Aortic aneurysm refers to the local or diffuse abnormal expansion of the aortic wall, which causes symptoms by compressing the surrounding organs. Aneurysm rupture is the main risk. It often occurs in the ascending aortic aortic arch, thoracic descending aorta, thoracic and abdominal aorta, and abdominal aorta. According to the structure, aortic aneurysms can be divided into true aortic aneurysms and false aortic aneurysms. Aortic aneurysms cause an increase in the medial pressure of the blood vessels, so they are progressively enlarged. If they develop for a long time, they eventually rupture, and the larger the tumor, the greater the possibility of rupture. According to statistics, if no surgical treatment is performed, 90% of thoracic aortic aneurysms die within 5 years, and 3/4 of abdominal aortic aneurysms die within 5 years.
主动脉夹层是另一种严重的主动脉疾病,主动脉夹层是指胸主动脉中膜破坏,血管壁内出血,血液进入血管壁中膜和外膜之间。由于血流的冲击作用,当主动脉夹层一旦形成,可使撕裂沿血流方向延伸,夹层和假腔扩大,并对真腔进行压迫。因此主动脉夹层患者可能出现的危险包括:(1)濒临血管完全破裂的威胁,一旦血管完全破裂,死亡率极高;(2)夹层逐渐扩大,并对真腔进行压迫,使血管远端供血减少。在大多数情况下,主动脉夹层继发于胸主动脉瘤,或与主动脉瘤同时存在。英国牛津血管病研究显示,主动脉夹层在自然人群中的发病率约为每年6/10万,男性多于女性,平均发病年龄为63岁。我国主动脉夹层发病率远高于欧美国家,且发病年龄较为年轻化。Aortic dissection is another serious aortic disease. Aortic dissection refers to the destruction of the media of the thoracic aorta, bleeding within the blood vessel wall, and blood entering between the media and the adventitia of the blood vessel wall. Due to the impact of blood flow, once the aortic dissection is formed, the tear can be extended in the direction of blood flow, the dissection and the false cavity can be enlarged, and the true cavity can be compressed. Therefore, the possible risks of patients with aortic dissection include: (1) the threat of complete rupture of the blood vessel. Once the blood vessel is completely ruptured, the mortality rate is extremely high; (2) the dissection gradually expands and compresses the true cavity to supply blood to the distal end cut back. In most cases, the aortic dissection secondary to the thoracic aortic aneurysm, or coexist with the aortic aneurysm. The British Oxford Vascular Disease Study shows that the incidence of aortic dissection in natural population is about 6/100,000 per year, with more men than women, with an average age of 63 years. The incidence of aortic dissection in my country is much higher than that in European and American countries, and the age of onset is relatively young.
主动脉瘤疾病均有可能涉及到分支动脉,一旦涉及到分支动脉想通过介入方法解决就会举步维艰。目前国内外已开展了动脉腔内治疗术,即采用微创方法,借助血管腔道向病变动脉内置入移植物即动脉覆膜支架来治疗动脉疾病改善供血,从而达到治疗目的。所说的血管腔内动脉覆膜支架是由管形刚性丝支架和固定于支架外侧的人造血管组成,管形刚性丝支架由具有弹性的刚性丝经Z形折叠后围成环形,再将多个环形刚性丝与人造血管缝合或粘合在一起组成管形覆膜支架。使用时,将管形覆膜支架轴向压缩后装载于输送器中,由输送器通过较小的股动脉、髂动脉、肱动脉送到病变动脉处再将其释放,由于金属丝支架的弹力作用自动恢复成直管状并紧贴于主动脉内壁,将动脉病变部位与血流隔离,从而达到了治疗目的。Aortic aneurysm diseases may involve branched arteries. Once the branched artery is involved, it will be difficult to resolve through interventional methods. At present, arterial cavity treatment has been carried out at home and abroad, that is, a minimally invasive method is used to implant arterial grafts into the diseased artery through the vascular channel to treat arterial disease and improve blood supply, so as to achieve the purpose of treatment. The endoluminal artery stent graft is composed of a tubular rigid wire stent and an artificial blood vessel fixed on the outside of the stent. The tubular rigid wire stent is formed of a flexible rigid wire that is folded in a Z shape to form a ring. A ring-shaped rigid wire and artificial blood vessel are sutured or bonded together to form a tubular stent graft. When in use, the tubular stent graft is compressed axially and loaded into the conveyor, which is delivered to the diseased artery through the smaller femoral artery, iliac artery, and brachial artery and then released due to the elastic force of the wire stent The effect is automatically restored to a straight tube and closely adheres to the inner wall of the aorta, isolating the artery lesion from the blood flow, thereby achieving the purpose of treatment.
现有技术中,涉及动脉分支治疗常用的支架包括烟囱支架、一体式多分支支架,开窗型支架,这些支架受限于支架的结构,往往需要临时定制,特别是对于一些连接角度比较小的分支,分支支架在连接分支血管与主体支架时,往往会有一个较大的弯折角度,使得分支支架受到主体支架的挤压而发生堵塞。In the prior art, commonly used stents related to arterial branch therapy include chimney stents, integrated multi-branch stents, and window-type stents. These stents are limited by the structure of the stent and often need to be customized temporarily, especially for some connection angles are relatively small When the branch stent is connected to the main vessel and the branch vessel, the branch stent often has a large bending angle, which causes the branch stent to be squeezed by the main stent and become blocked.
申请内容Application content
本申请的目的在于提供一种能防止内漏的内嵌分支支架,以及设置有所述内嵌分支支架的血管支架。The purpose of the present application is to provide an in-line branch stent capable of preventing endoleak, and a blood vessel stent provided with the in-line branch stent.
为了解决上述技术问题,本申请提供了一种内嵌分支支架,其包括主体管,所述主体管包括主体覆膜,所述主体覆膜上开设有至少一开窗,所述内嵌分支支架还包括设置于所述主体管的内腔的至少一内嵌分支管,至少一所述内嵌分支管自至少一所述开窗朝所述主体管的内腔延伸,所述内嵌分支管的轴线与主体管的轴线之间的角度大于0度。In order to solve the above technical problems, the present application provides an in-line branching bracket, which includes a main body tube, and the main body tube includes a main body covering film, at least one window is opened on the main body covering film, and the in-line branching support It also includes at least one in-line branch tube disposed in the inner cavity of the main body tube, at least one in-line branch tube extending from at least one window opening toward the inner cavity of the main body tube, the in-line branch tube The angle between the axis of and the axis of the main body tube is greater than 0 degrees.
本申请还提供一种血管支架,其包括内嵌分支支架,以及至少一分支管,所述内嵌分支支架包括主体管,所述主体管包括主体覆膜,所述主体覆膜上开设有至少一开窗,所述内嵌分支支架还包括设置于所述主体管的内腔的至少一内嵌分支管,至少一所述内嵌分支 管自至少一所述开窗朝所述主体管的内腔延伸,所述内嵌分支管的轴线与主体管的轴线之间的角度大于0度,所述分支管的近端穿过所述开窗插接于所述内嵌分支支架的内嵌分支管内。The present application also provides a vascular stent including an in-line branch stent and at least one branch tube. The in-line branch stent includes a main body tube, and the main body tube includes a main body membrane, and the main body membrane is provided with at least one A window opening, the in-line branch bracket further includes at least one in-line branch tube disposed in an inner cavity of the main body tube, at least one in-line branch tube from at least one of the window opening toward the main body tube The inner cavity extends, and the angle between the axis of the embedded branch tube and the axis of the main body tube is greater than 0 degrees, and the proximal end of the branch tube is inserted into the inline branch support through the window opening Inside the branch pipe.
本申请提供的血管支架的内嵌分支支架包括主体管及设置于所述主体管的内腔的至少一分支管,所述内嵌分支管的轴线与主体管的轴线之间的角度大于0度。当所述分支管需要连接于所述内嵌分支支架上时,将所述分支管的近端插入所述内嵌分支管的内腔,所述内嵌分支管能密封地包裹所述分支管的近端的外周面,从而能有效地防止内漏,且方便在内嵌分支支架上插入分支管。另外,由于内嵌分支管的轴线与主体管的轴线之间的角度大于0度,因此,所述分支管倾斜地连接于所述主体管上,能防止所述分支管被释放至分支血管中之后由于在与主体管的连接处由于弯曲度过大而被挤压导致的折弯,从而防止所述分支管堵塞。The embedded branch stent of the vascular stent provided by the present application includes a main body tube and at least one branch tube disposed in the lumen of the main body tube, an angle between the axis of the embedded branch tube and the axis of the main body tube is greater than 0 degrees . When the branch tube needs to be connected to the embedded branch bracket, insert the proximal end of the branch tube into the lumen of the embedded branch tube, the embedded branch tube can sealingly wrap the branch tube The outer peripheral surface of the proximal end can effectively prevent internal leakage and facilitate the insertion of the branch tube on the embedded branch bracket. In addition, since the angle between the axis of the embedded branch tube and the axis of the main body tube is greater than 0 degrees, the branch tube is obliquely connected to the main body tube, which can prevent the branch tube from being released into the branch blood vessel Afterwards, the branch pipe is prevented from being blocked due to bending caused by being squeezed due to excessive bending at the connection with the main body pipe.
附图说明BRIEF DESCRIPTION
为了更清楚地说明本申请实施例中的技术方案,下面将对实施例中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本申请的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的明显变形方式。In order to more clearly explain the technical solutions in the embodiments of the present application, the following will briefly introduce the drawings required in the embodiments. Obviously, the drawings in the following description are only some embodiments of the present application. For those of ordinary skill in the art, without paying any creative work, other obvious deformation methods can be obtained according to these drawings.
图1是本申请第一实施例提供的血管支架的结构示意图。FIG. 1 is a schematic structural diagram of a vascular stent provided in the first embodiment of the present application.
图2是图1中的内嵌分支支架的结构示意图。FIG. 2 is a schematic structural diagram of the in-line branch bracket in FIG. 1.
图3是图2中的环状波形支撑杆的立体结构示意图。FIG. 3 is a schematic perspective view of the ring-shaped wave supporting rod in FIG. 2.
图4是图1中的环状波形支撑杆连接至主体覆膜上的结构示意图。FIG. 4 is a schematic view of the structure of the ring-shaped wave supporting rod in FIG. 1 connected to the main body film.
图5a-图5c是本申请内嵌分支支架的内嵌分支管的其他形式的结构示意图。5a-5c are structural schematic diagrams of other forms of an embedded branch tube with an embedded branch bracket of the present application.
图6是图1中的内嵌分支支架近端部分的放大图。6 is an enlarged view of the proximal end portion of the in-line branch stent in FIG. 1.
图7a及图7b是本申请的内嵌分支支架的开窗的四周的显影结构不同结构示意图。7a and 7b are schematic diagrams of different development structures around the window of the embedded branching bracket of the present application.
图8是本申请第二实施例提供的血管支架的内嵌分支支架的结构示意图。FIG. 8 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a second embodiment of the present application.
图9是本申请第三实施例提供的血管支架的内嵌分支支架的结构示意图。9 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a third embodiment of the present application.
图10是本申请第四实施例提供的血管支架的内嵌分支支架的结构示意图。10 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a fourth embodiment of the present application.
具体实施方式detailed description
下面将结合本申请实施例中的附图,对本申请实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本申请一部分实施例,而不是全部的实施例。基于本申请中的实施例,本领域普通技术人员在没有付出创造性劳动前提下所获得的所有其它实施例,都属于本申请保护的范围。The technical solutions in the embodiments of the present application will be described clearly and completely in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, but not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by a person of ordinary skill in the art without paying any creative work fall within the protection scope of the present application.
此外,以下各实施例的说明是参考附加的图示,用以例示本申请可用以实施的特定实施例。本申请中所提到的方向用语,例如,“上”、“下”、“前”、“后”、“左”、“右”、“内”、“外”、“侧面”等,仅是参考附加图式的方向,因此,使用的方向用语是为了更好、更清楚地说明及理解本申请,而不是指示或暗指所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本申请的限制。In addition, the descriptions of the following embodiments refer to additional drawings to illustrate specific embodiments that can be implemented by the present application. Directional terms mentioned in this application, such as "upper", "lower", "front", "rear", "left", "right", "inner", "outer", "side", etc., only It refers to the directions of the attached drawings. Therefore, the direction terms are used for better and clearer explanation and understanding of the application, rather than indicating or implying that the device or element referred to must have a specific orientation, with a specific orientation The construction and operation cannot therefore be understood as a limitation of this application.
在本申请的描述中,本申请所述“近端”是指靠近心脏位置的一端,所述“远端”为远离心脏位置的一端。本申请中所述的高、低是相对于主体管覆膜而言,超出主体管覆膜的端面称为高,未超出主体管覆膜端面的称为低,该定义只是为了表述方便,并不能理解为对本申请的限制。In the description of the present application, the “proximal end” in the present application refers to the end close to the position of the heart, and the “distal end” refers to the end far from the position of the heart. The high and low mentioned in this application are relative to the body tube coating. The end surface that exceeds the body tube coating is called high, and the one that does not exceed the body tube coating is called low. This definition is just for convenience of expression, and It cannot be understood as a limitation of this application.
请参阅图1,图1是本申请第一实施例提供的血管支架的结构示意图。本申请提供一 种血管支架100,其包括一内嵌分支支架20,以及至少一分支管40。所述内嵌分支支架20包括一主体管21及至少一内嵌分支管25,所述主体管21为等径结构或者非等径结构。所述主体管21包括管状的主体覆膜210,至少一所述内嵌分支管25设置于所述内嵌分支支架20的主体管21的内腔。所述主体覆膜210上开设有至少一开窗211,至少一所述内嵌分支管25自至少一所述开窗211朝所述主体管21的内腔延伸。所述内嵌分支管25的轴线与主体管21的轴线之间的角度大于0度。所述分支管40的近端部穿过所述开窗211插接于所述内嵌分支支架20的内嵌分支管25的内腔,分支管40密封套接于所述内嵌分支管25的近端。Please refer to FIG. 1, which is a schematic structural diagram of a vascular stent provided in a first embodiment of the present application. The present application provides a vascular stent 100 including an embedded branch stent 20 and at least one branch tube 40. The in-line branching bracket 20 includes a main body tube 21 and at least one in-line branching tube 25. The main body tube 21 is of an equal-diameter structure or a non-equi-diameter structure. The main body tube 21 includes a tubular main body film 210, and at least one of the embedded branch tubes 25 is disposed in the inner cavity of the main body tube 21 of the embedded branch bracket 20. At least one window 211 is provided on the main body film 210, and at least one embedded branch tube 25 extends from the at least one window 211 toward the inner cavity of the main body tube 21. The angle between the axis of the embedded branch pipe 25 and the axis of the main body pipe 21 is greater than 0 degrees. The proximal end of the branch pipe 40 is inserted into the inner cavity of the embedded branch pipe 25 of the embedded branch bracket 20 through the window 211, and the branch pipe 40 is hermetically sleeved with the embedded branch pipe 25 The near end.
本实施例中,主体管21为非等径结构,所述主体管21近端直径大于远端直径,所述主体管21的直径由近端向远端逐渐变细。In this embodiment, the main body tube 21 has a non-equal-diameter structure. The proximal end diameter of the main body pipe 21 is larger than the distal end diameter, and the diameter of the main body pipe 21 tapers from the proximal end to the distal end.
具体的,所述主体覆膜210为管状结构,其横端面的形状是与血管配合的圆形、椭圆形或棱形。至少一所述开窗211开设于所述管状覆膜上,所述开窗211可以是圆形孔、椭圆形孔、棱形孔或无规则曲面形等。所述主体覆膜210采用涤纶布、PTFE、PET或者其他高分子材料制成。Specifically, the main body coating 210 is a tubular structure, and the shape of the lateral end surface is a circle, an ellipse, or a prism that matches the blood vessel. At least one of the window openings 211 is opened on the tubular film. The window openings 211 may be circular holes, elliptical holes, prismatic holes, or irregular curved surfaces. The main body film 210 is made of polyester cloth, PTFE, PET or other polymer materials.
所述内嵌分支支架20及所述分支管40均为自膨胀式的支架,当内嵌分支支架20或所述分支管40通过鞘管输送时,所述内嵌分支支架20或所述分支管40的直径可收缩至较小状态以便在鞘管中输送;当所述内嵌分支支架20或所述分支管40在血管内释放时,所述内嵌分支支架20或所述分支管40可自动膨胀至所需形状尺寸,以使所述内嵌分支支架20或所述分支管40能支撑于血管病变位置的内壁上,所述内嵌分支支架20或所述分支管40对所述血管的内壁产生径向的支撑作用,从而能重建血管。The embedded branch stent 20 and the branch tube 40 are both self-expanding stents. When the embedded branch stent 20 or the branch tube 40 is delivered through the sheath tube, the embedded branch stent 20 or the branch The diameter of the tube 40 can be reduced to a smaller state for delivery in the sheath; when the embedded branch stent 20 or the branch tube 40 is released in the blood vessel, the embedded branch stent 20 or the branch tube 40 It can be automatically expanded to the required shape and size, so that the embedded branch stent 20 or the branch tube 40 can be supported on the inner wall of the vascular lesion, and the embedded branch stent 20 or the branch tube 40 The inner wall of the blood vessel produces radial support, which can rebuild the blood vessel.
本申请的血管支架100的内嵌分支支架20包括一主体管21及设置于所述主体管21的内腔的至少一分支管40,所述内嵌分支管25的轴线与主体管21的轴线之间的角度大于0度。当所述分支管40需要连接于所述内嵌分支支架20上时,将所述分支管40的近端插入所述内嵌分支管25的内腔,所述内嵌分支管25能密封地包裹所述分支管40的近端的外周面,从而能有效地防止分支管40与内嵌分支支架20的连接位置发生内漏,且方便在内嵌分支支架20上插入分支管40。另外,由于内嵌分支管25的轴线与主体管21的轴线之间的角度大于0度,因此,所述分支管40倾斜地连接于所述主体管21上,能防止所述分支管40在释放至分支血管后由于弯曲的幅度过大而被挤压导致的折弯,从而防止所述分支管40堵塞。The embedded branch stent 20 of the vascular stent 100 of the present application includes a main body tube 21 and at least one branch tube 40 disposed in the lumen of the main body tube 21, the axis of the embedded branch tube 25 and the axis of the main body tube 21 The angle between is greater than 0 degrees. When the branch tube 40 needs to be connected to the embedded branch bracket 20, insert the proximal end of the branch tube 40 into the inner cavity of the embedded branch tube 25, the embedded branch tube 25 can be sealed The outer peripheral surface of the proximal end of the branch tube 40 is wrapped, so as to effectively prevent the internal leakage of the connection position of the branch tube 40 and the embedded branch bracket 20, and facilitate the insertion of the branch tube 40 on the embedded branch bracket 20. In addition, since the angle between the axis of the embedded branch pipe 25 and the axis of the main body pipe 21 is greater than 0 degrees, the branch pipe 40 is obliquely connected to the main body pipe 21, which prevents the branch pipe 40 from After being released to the branch blood vessel, it is bent due to being squeezed due to excessive bending amplitude, thereby preventing the branch tube 40 from being blocked.
优选地,所述内嵌分支管25的轴线与所述主体管21的轴线之间的角度为5度、45度或5度~45度的范围内的值。具体的,所述主体管21及所述内嵌分支管25在伸展状态下,所述内嵌分支管25倾斜连接于所述主体管21,即内嵌分支管25的轴线与所述主体管21的轴线之间的角度为5度、45度或5度~45度的范围内的值。当所述内嵌分支管25内插接有分支管40的近端部时,所述分支管40的近端的轴线与所述内嵌分支管25的轴线重合,从而使所述分支管40倾斜地连接于所述主体管21上。Preferably, the angle between the axis of the inline branch pipe 25 and the axis of the main body pipe 21 is a value within a range of 5 degrees, 45 degrees, or 5 degrees to 45 degrees. Specifically, when the main body tube 21 and the embedded branch pipe 25 are in an extended state, the embedded branch pipe 25 is obliquely connected to the main body pipe 21, that is, the axis of the embedded branch pipe 25 and the main body pipe The angle between the axes of 21 is a value in the range of 5 degrees, 45 degrees, or 5 degrees to 45 degrees. When the proximal end of the branch pipe 40 is inserted into the embedded branch pipe 25, the axis of the proximal end of the branch pipe 40 coincides with the axis of the embedded branch pipe 25, so that the branch pipe 40 It is connected to the main body tube 21 obliquely.
在其他实施例中,所述内嵌分支管25的轴线与所述主体管21的轴线之间的角度可以根据需要选择合适的角度值。In other embodiments, the angle between the axis of the inline branch pipe 25 and the axis of the main body pipe 21 can be selected according to need.
所述内嵌分支管25的轴向延伸长度大于或等于2mm,优选地,所述内嵌分支管25的轴向延伸长度为2mm、100mm或2mm~100mm的范围内的值。所述内嵌分支管25的内径大于或等于2mm,优选地,所述内嵌分支管的内径为2mm、5mm或2mm~5mm的范围内的值。所述内嵌分支管25作为主体管21与分支管40之间连接的锚定部,所述内嵌分支管25的轴向延伸长度越长,所述内嵌分支管25与分支管40的可密封套接的长度越长,使分支管40的近端部越能稳定地连接于主体管21上,从而达到更好的防漏效果。The axial extension length of the embedded branch pipe 25 is greater than or equal to 2 mm. Preferably, the axial extension length of the embedded branch pipe 25 is a value in the range of 2 mm, 100 mm, or 2 mm to 100 mm. The inner diameter of the embedded branch pipe 25 is greater than or equal to 2 mm. Preferably, the inner diameter of the embedded branch pipe is a value in the range of 2 mm, 5 mm, or 2 mm to 5 mm. The embedded branch pipe 25 serves as an anchor portion for connecting between the main body pipe 21 and the branch pipe 40. The longer the axial extension of the embedded branch pipe 25, the The longer the length of the sealable sleeve is, the more stable the proximal end portion of the branch tube 40 can be connected to the main body tube 21, thereby achieving a better leak-proof effect.
请一并参阅图2至图4,图2是图1中的内嵌分支支架的结构示意图;图3是图2中 的环状波形支撑杆的立体结构示意图;图4是图1中的环状波形支撑杆连接至主体覆膜上的结构示意图。所述主体管21还包括设置于在所述主体覆膜210的内周面或外周面的主体支撑骨架212,具体的,所述主体支撑骨架212通过缝线缝合在所述主体覆膜210的内周面或外周面。所述主体支撑骨架212可以是弹性的金属支撑骨架或弹性的非金属如高分子材料的支撑骨架。本实施例中,所述主体支撑骨架212为镍合金支架,当主体支撑骨架212通过鞘管输送时,所述主体支撑骨架212的直径可收缩至较小状态以便在鞘管中输送;当所述主体支撑骨架212在血管内释放时,主体支撑骨架212可自动膨胀至所需形状尺寸,以使所述主体支撑骨架212能支撑于对应的血管的内壁上。Please refer to FIG. 2 to FIG. 4 together. FIG. 2 is a schematic structural view of the in-line branch support in FIG. 1; FIG. 3 is a perspective structural schematic view of the annular wave-shaped support rod in FIG. 2; FIG. Schematic diagram of the structure of the corrugated support rod connected to the main body film. The main body tube 21 further includes a main body support frame 212 provided on the inner or outer circumferential surface of the main body film 210. Specifically, the main body support frame 212 is sewn to the main body film 210 by a suture. Inner peripheral surface or outer peripheral surface. The main body supporting framework 212 may be an elastic metal supporting framework or an elastic non-metallic supporting framework such as a polymer material. In this embodiment, the main body supporting framework 212 is a nickel alloy stent. When the main body supporting framework 212 is transported through the sheath, the diameter of the main body supporting framework 212 may be contracted to a smaller state for transport in the sheath; when When the main body supporting framework 212 is released in the blood vessel, the main body supporting framework 212 can automatically expand to the desired shape and size, so that the main body supporting framework 212 can be supported on the inner wall of the corresponding blood vessel.
主体支撑骨架212可以采用镍合金管激光切割而成,也可以采用金属丝如镍合金丝编织而成。主体支撑骨架212的网状结构的疏密程度根据需要设定。本实施例中,所述主体支撑骨架212包括若干个Z形或正弦波形的环状波形支撑杆2120,这些环状波形支撑杆2120沿所述主体覆膜210的轴向间隔排列,即这些环状波形支撑杆2120从所述主体管21近端到远端依次平行间隙排布。The main body supporting framework 212 may be laser-cut with a nickel alloy tube, or may be woven with metal wires such as nickel alloy wires. The degree of density of the mesh structure of the main body supporting skeleton 212 is set as required. In this embodiment, the main body support frame 212 includes a plurality of Z-shaped or sinusoidal wave-shaped support rods 2120, and these ring-shaped support rods 2120 are arranged at intervals along the axial direction of the main body coating 210, that is, these rings The wave-shaped support rods 2120 are arranged in parallel with a gap from the proximal end to the distal end of the main body tube 21.
每一环状波形支撑杆2120可以是等高波支撑杆或高低波支撑杆等,所述等高波支撑杆是指环状波形支撑杆2120上的各个波峰的高度相同,且各个波谷的高度也相同,即,各个波峰及各个波谷分别在同一平面上。所述高低波支撑杆是指环状波形支撑杆2120上的至少两个波峰的高度不相同,及/或至少两个波谷的高度不相同。本实施例中,所述主体管21的环状波形支撑杆2120均为等高波支撑杆。Each ring-shaped wave support bar 2120 may be a high-wave wave support bar or a high-low wave support bar, etc. The contour wave support bar means that the height of each wave peak on the ring-shaped wave support bar 2120 is the same, and the height of each wave valley is the same That is, the peaks and troughs are on the same plane. The high and low wave support bars mean that the heights of at least two wave peaks on the ring-shaped wave support bar 2120 are different, and/or the heights of at least two wave troughs are different. In this embodiment, the annular wave-shaped support rods 2120 of the main body tube 21 are all constant-wave support rods.
如图3所示,每一环状波形支撑杆2120的每一Z形或正弦波形均包括一波峰2121、一波谷2123及连接于所述波峰2121与所述波谷2123之间的一连接杆2125。每一个环状波形支撑杆2120通过一条超弹性镍钛丝编织而成,超弹性镍钛合金丝可选择的丝径(即直径)范围为0.2mm~0.55mm。每一个环状波形支撑杆2120上设置有一连接套2127,所述连接套2127用于将所述超弹性镍钛丝的相对的两端连接以形成一环状波形支撑杆2120,即,超弹性镍钛丝相对的两端均收纳于所述连接套2127内,然后再通过机械压紧或者焊接方式将镍钛丝的两个端固定在连接套2127的内部。As shown in FIG. 3, each Z-shaped or sinusoidal waveform of each annular waveform support rod 2120 includes a peak 2121, a valley 2123, and a connecting rod 2125 connected between the peak 2121 and the valley 2123 . Each annular wave-shaped support rod 2120 is woven by a super-elastic nickel-titanium wire, and the selectable wire diameter (ie diameter) of the super-elastic nickel-titanium alloy wire is 0.2 mm to 0.55 mm. Each annular wave-shaped support rod 2120 is provided with a connection sleeve 2127 for connecting opposite ends of the superelastic nickel-titanium wire to form an annular wave-shaped support rod 2120, that is, superelastic Both ends of the nickel-titanium wire are accommodated in the connecting sleeve 2127, and then the two ends of the nickel-titanium wire are fixed inside the connecting sleeve 2127 by mechanical compression or welding.
本实施例中,所述环状波形支撑杆2120采用0.4mm直径的镍钛丝编织而成,Z形或正弦波数量为9个,环状波形支撑杆2120的垂直高度为8-15mm。In this embodiment, the annular wave-shaped support rod 2120 is braided with 0.4 mm diameter nickel-titanium wire, the number of Z-shaped or sinusoidal waves is 9, and the vertical height of the annular wave-shaped support rod 2120 is 8-15 mm.
在其他实施例中,所述主体支撑骨架212可以是编织的网状结构或切割而成的网状结构。In other embodiments, the main body supporting skeleton 212 may be a woven mesh structure or a cut mesh structure.
在其他实施例中,所述环状波形支撑杆2120的正弦波数量可以根据需要进行确定,环状波形支撑杆2120的垂直高度可以是任意高度。In other embodiments, the number of sine waves of the annular wave-shaped support rod 2120 may be determined according to needs, and the vertical height of the annular wave-shaped support rod 2120 may be any height.
如图4所示,所述主体支撑骨架212的每一环状波形支撑杆2120通过缝线23缝合在主体覆膜210上,即,所述缝线23可以沿着每一环状波形支撑杆2120的波形走向而伴随整个主体支撑骨架212。所述缝线23也可以通过若干非等间距分布的缝合小结将每一环状波形支撑杆2120缝合在主体覆膜210上。所述缝线23的直径选择范围为0.05mm-0.25mm。或者主体支撑骨架212也可以通过热压的方式与主体覆膜210固定连接。As shown in FIG. 4, each ring-shaped wave support rod 2120 of the main body support frame 212 is sewn to the body film 210 by a suture 23, that is, the thread 23 can be along each ring-shaped wave support rod The wave shape of 2120 is accompanied by the entire main body supporting skeleton 212. The suture 23 can also be sutured to the main body covering film 210 by a plurality of unequally spaced stitching knots. The selection range of the diameter of the suture 23 is 0.05mm-0.25mm. Alternatively, the main body support frame 212 may be fixedly connected to the main body film 210 by hot pressing.
所述内嵌分支管25与所述开窗211之间连接有过渡覆膜251,所述过渡覆膜251为管状形或圆锥形环状,其横端面的形状与所述开窗211的形状对应,即可以是圆形、椭圆形或棱形等。所述过渡覆膜251自所述开窗211朝向所述主体管21的内腔延伸。所述过渡覆膜251的一端密封连接于所述开窗211的边缘,所述过渡覆膜251的另一端密封连接于所述内嵌分支管25的近端。具体的,所述过渡覆膜251的近端的边缘密封连接于所述主体覆膜210于所述开窗211的边缘,所述过渡覆膜251的远端的边缘密封连接于所述内嵌分支管25的近端的周面,所述过渡覆膜251的近端的外径大于远端的外径。所述过渡 覆膜251采用涤纶布、PTFE、PET或者其他高分子材料制成。由于所述内嵌分支管25和开窗211之间连接有过渡覆膜251,所述过渡覆膜251能密封连接于所述主体覆膜210与内嵌分支管25之间,因此,所述过渡覆膜251能防止内嵌分支管25与开窗211之间发生内漏。A transition film 251 is connected between the embedded branch pipe 25 and the window 211, and the transition film 251 is tubular or conical ring-shaped, and the shape of its lateral end surface and the shape of the window 211 Correspondingly, it can be circular, elliptical or prismatic. The transition film 251 extends from the window 211 toward the inner cavity of the main body tube 21. One end of the transition film 251 is hermetically connected to the edge of the window 211, and the other end of the transition film 251 is hermetically connected to the proximal end of the embedded branch tube 25. Specifically, the edge of the proximal end of the transition film 251 is sealingly connected to the edge of the main body film 210 at the window 211, and the edge of the distal end of the transition film 251 is sealingly connected to the inlay On the peripheral surface of the proximal end of the branch tube 25, the outer diameter of the proximal end of the transition coating 251 is greater than the outer diameter of the distal end. The transition film 251 is made of polyester cloth, PTFE, PET or other polymer materials. Since the transitional film 251 is connected between the embedded branch pipe 25 and the window 211, the transitional film 251 can be sealingly connected between the main body film 210 and the embedded branch pipe 25, therefore, the The transition film 251 can prevent internal leakage between the embedded branch pipe 25 and the window 211.
在另一种实施方式中,所述过渡覆膜251的远端的外径大于近端的外径,从而使所述过渡覆膜形成内凹部,所述内凹部具有导引作用。或者所述过渡覆膜251的远端的截面相对于开窗向内凹以形成导引部,使分支管40与内嵌分支管25的连接更为顺畅。In another embodiment, the outer diameter of the distal end of the transition coating 251 is greater than the outer diameter of the proximal end, so that the transition coating forms an inner recess, and the inner recess has a guiding effect. Or the cross-section of the distal end of the transition film 251 is recessed inward relative to the window opening to form a guide portion, so that the connection of the branch pipe 40 and the embedded branch pipe 25 is smoother.
本实施例中,所述过渡覆膜251的近端通过缝线缝合于所述开窗211的边缘的主体覆膜210上,所述过渡覆膜251的远端通过缝线缝合于所述内嵌分支管25的近端。所述过渡覆膜251远端可与内嵌分支管25的近端为一体结构。In this embodiment, the proximal end of the transition film 251 is stitched to the main body film 210 at the edge of the window 211 by a suture, and the distal end of the transition film 251 is stitched to the inside by a stitch The proximal end of the branch tube 25 is embedded. The distal end of the transition membrane 251 may be an integral structure with the proximal end of the embedded branch tube 25.
在其他实施例中,所述过渡覆膜251的近端与所述主体覆膜210之间的连接可以通过医用胶水连接,所述过渡覆膜251的远端与内嵌分支管25之间的连接也可以通过医用胶水连接。In other embodiments, the connection between the proximal end of the transition coating 251 and the main body coating 210 may be connected by medical glue, and the distal end of the transition coating 251 and the embedded branch tube 25 The connection can also be via medical glue.
在其他实施例中,所述过渡覆膜251上还可以设置支撑骨架,以撑开所述过渡覆膜251。所述支撑骨架可以通过缝线缝合于所述过渡覆膜251的内周面或外周面。In other embodiments, a support skeleton may be provided on the transition coating 251 to stretch the transition coating 251. The support frame may be stitched to the inner peripheral surface or the outer peripheral surface of the transition coating 251 by a suture.
所述内嵌分支管25包括管状形的内嵌分支覆膜253及设置于所述内嵌分支覆膜253上的支撑骨架255,即所述支撑骨架255的内周面或外周面上贴合有所述内嵌分支覆膜253。具体的,所述支撑骨架255通过缝线缝合或者热压的方式固定在所述内嵌分支覆膜253的内周面或外周面或者多层覆膜之间。内嵌分支覆膜253的横端面的形状是与分支管40的近端配合的圆形、椭圆形或棱形,所述内嵌分支覆膜253的近端连接于所述过渡覆膜251的远端。所述内嵌分支覆膜253的远端朝所述主体管21的内腔延伸。伸展状态下,所述内嵌分支覆膜253的轴线与所述主体管21的轴线之间的角度大于0度。所述主体覆膜210采用涤纶布、PTFE、PET或者其他高分子材料制成。The embedded branch pipe 25 includes a tubular shaped embedded branch coating 253 and a support frame 255 provided on the embedded branch coating 253, that is, the inner or outer peripheral surfaces of the support frame 255 are bonded together There is the embedded branch film 253. Specifically, the support frame 255 is fixed between the inner peripheral surface or the outer peripheral surface of the embedded branch coating 253 or the multilayer coating by means of stitching or hot pressing. The shape of the lateral end surface of the embedded branch coating 253 is a circle, an ellipse, or a prism matching the proximal end of the branch tube 40. The proximal end of the embedded branch coating 253 is connected to the transition coating 251. remote. The distal end of the embedded branch membrane 253 extends toward the inner cavity of the main body tube 21. In the extended state, the angle between the axis of the embedded branch film 253 and the axis of the main body tube 21 is greater than 0 degrees. The main body film 210 is made of polyester cloth, PTFE, PET or other polymer materials.
所述支撑骨架255可以是弹性的金属支撑骨架或弹性的非金属如高分子材料的支撑骨架。本实施例中,所述支撑骨架255为镍合金支架,当支撑骨架255通过鞘管输送时,所述支撑骨架255的直径可收缩至较小状态以便在鞘管中输送;当所述支撑骨架255释放时,支撑骨架255可自动膨胀至所需形状尺寸。所述支撑骨架255能支撑所述内嵌分支覆膜253,使所述内嵌分支覆膜253保持张开状态,方便所述分支管40的连接。The supporting framework 255 may be an elastic metal supporting framework or an elastic non-metallic supporting framework such as a polymer material. In this embodiment, the support frame 255 is a nickel alloy stent. When the support frame 255 is transported through the sheath tube, the diameter of the support frame 255 can be contracted to a smaller state for transportation in the sheath tube; when the support frame When 255 is released, the support frame 255 can automatically expand to the desired shape and size. The support frame 255 can support the embedded branch coating film 253 to keep the embedded branch coating film 253 in an open state, which is convenient for the connection of the branch tube 40.
支撑骨架255可以采用镍合金管激光切割而成,也可以采用金属丝如镍合金丝编织而成。支撑骨架255的网状结构的疏密程度根据需要设定。本实施例中,所述支撑骨架255包括若干个Z形或正弦波形的环状波形支撑杆,这些环状波形支撑杆沿所述内嵌分支覆膜253的轴向间隔排列,即这些环状波形支撑杆从所述内嵌分支覆膜253近端到远端依次平行间隙排布。The support frame 255 may be laser-cut with a nickel alloy tube, or may be woven with metal wires such as nickel alloy wires. The degree of density of the mesh structure supporting the skeleton 255 is set as required. In this embodiment, the support frame 255 includes a plurality of Z-shaped or sinusoidal ring-shaped wave-shaped support rods, and these ring-shaped wave-shaped support rods are arranged at intervals along the axial direction of the embedded branch coating 253, that is, these ring-shaped support rods The wave-shaped support rods are arranged in parallel gaps from the proximal end to the distal end of the embedded branch covering film 253 in sequence.
所述内嵌分支管25的内径小于或等于所述分支管40的近端的外径,当分支管40的近端部穿过所述开窗211插入所述内嵌分支管25内释放后,所述支撑骨架255挤压所述分支管40的外壁,使分支管40与所述内嵌分支管25的连接更牢固,且能维持进入所述内嵌分支管25内的分支管40的形状;所述内嵌分支覆膜253包裹于所述分支管40的近端的外周面,从而能进一步防止内漏。The inner diameter of the embedded branch tube 25 is less than or equal to the outer diameter of the proximal end of the branch tube 40. When the proximal end of the branch tube 40 is inserted into the embedded branch tube 25 through the window 211 and released, The support frame 255 squeezes the outer wall of the branch pipe 40 to make the connection of the branch pipe 40 and the embedded branch pipe 25 firmer, and to maintain the shape of the branch pipe 40 entering the embedded branch pipe 25 The embedded branch covering film 253 is wrapped around the outer peripheral surface of the proximal end of the branch tube 40, so as to further prevent internal leakage.
请一并参阅图5a至图5c,图5a-图5c是本申请内嵌分支支架的内嵌分支管的其他形式的结构示意图。所述内嵌分支管25的支撑骨架255可选自如图5a及图5b所示的任一环形支撑架或图5c所示的网状骨架。所述环形支撑架包括若干个Z形或正弦波形的环状波形支撑杆,这些环状波形支撑杆沿所述内嵌分支管25的轴向间隔排列。所述网状骨架可以是编织或者切割制成。Please refer to FIG. 5a to FIG. 5c together. FIG. 5a to FIG. 5c are schematic structural diagrams of other forms of the embedded branch tube with the embedded branch bracket of the present application. The support frame 255 of the embedded branch pipe 25 can be selected from any ring-shaped support frame as shown in FIGS. 5a and 5b or the mesh frame shown in FIG. 5c. The ring-shaped support frame includes a number of Z-shaped or sinusoidal wave-shaped ring-shaped support rods, which are arranged at intervals along the axial direction of the embedded branch pipe 25. The mesh skeleton may be woven or cut.
在其他实施例中,内嵌分支管25仅包括内嵌分支覆膜253,即内嵌分支覆膜253上 的支撑骨架255可以省略,所述内嵌分支覆膜253的近端连接于过渡覆膜251的远端。In other embodiments, the embedded branch tube 25 includes only the embedded branch coating 253, that is, the supporting frame 255 on the embedded branch coating 253 can be omitted, and the proximal end of the embedded branch coating 253 is connected to the transition coating The distal end of the membrane 251.
在其他实施例中,内嵌分支管25仅包括支撑骨架255,即所述支撑骨架255上的内嵌分支覆膜253可以省略,所述支撑骨架255为裸支架,所述裸支架可为编织或者切割结构的裸支架。所述裸支架的近端连接于所述过渡覆膜251的远端。In other embodiments, the embedded branch pipe 25 only includes a support frame 255, that is, the embedded branch film 253 on the support frame 255 may be omitted, the support frame 255 is a bare support, and the bare support may be a braid Or cut the bare bracket of the structure. The proximal end of the bare stent is connected to the distal end of the transition membrane 251.
在其他实施例中,所述内嵌分支管25包括直接连接于所述开窗211的内嵌分支覆膜253,所述内嵌分支覆膜253与主体覆膜210上邻近开窗211的部分密封连接,所述内嵌分支覆膜253用于包裹分支管40的近端。具体的,所述内嵌分支管25与所述开窗211之间的过渡覆膜251可以省略,而是通过所述内嵌分支覆膜253的近端直接密封地连接于所述主体覆膜210于所述开窗211的边缘。所述内嵌分支覆膜253为管状结构,所述内嵌分支覆膜253的横端面的形状是与开窗211的形状一致,具体为圆形、椭圆形或棱形等。所述内嵌分支覆膜253上可以设置有弹性的内嵌分支骨架,所述内嵌分支骨架贴合于所述内嵌分支覆膜253的内周面或外周面。所述内嵌分支骨架能使连接于内嵌分支管25内的分支管40的连接更牢固,并能维持进入所述内嵌分支管25内的分支管40的形状。在其他实施例中,所述内嵌分支覆膜253上的内嵌分支骨架也可以省略。In other embodiments, the in-line branch tube 25 includes an in-line branch film 253 directly connected to the window 211. The in-line branch film 253 and the main body film 210 are adjacent to the window 211. For sealing connection, the embedded branch film 253 is used to wrap the proximal end of the branch tube 40. Specifically, the transition film 251 between the embedded branch tube 25 and the window 211 may be omitted, but directly connected to the main body film through the proximal end of the embedded branch film 253 directly and sealingly 210 at the edge of the window 211. The embedded branch coating film 253 has a tubular structure, and the shape of the lateral end surface of the embedded branch coating film 253 is consistent with the shape of the window 211, and is specifically circular, elliptical, or prismatic. The embedded branch coating film 253 may be provided with an elastic embedded branch skeleton, and the embedded branch skeleton is attached to the inner peripheral surface or the outer peripheral surface of the embedded branch coating film 253. The embedded branch skeleton can make the connection of the branch pipe 40 connected in the embedded branch pipe 25 firmer, and can maintain the shape of the branch pipe 40 entering the embedded branch pipe 25. In other embodiments, the embedded branch skeleton on the embedded branch coating 253 may also be omitted.
如图6所示,所述开窗211的边缘设置有一支撑件214,所述支撑件214用于撑开所述开窗211,以使开窗211保持开口状态。所述支撑件214是固定于所述开窗211边缘的支撑杆,所述支撑杆沿所述开窗211的边缘延伸,所述支撑杆适应所述开窗211的边缘形状,具体的,所述支撑杆可以为圆形、椭圆形或棱形的环状结构。As shown in FIG. 6, a support member 214 is provided at the edge of the window opening 211, and the support member 214 is used to support the window opening 211 to keep the window opening 211 open. The support member 214 is a support rod fixed to the edge of the window opening 211, the support rod extends along the edge of the window opening 211, the support rod adapts to the shape of the edge of the window opening 211, specifically, The support rod may have a circular, elliptical or prismatic ring structure.
优选地,所述支撑件214是沿所述开窗211的边缘延伸的支撑环,所述支撑环具有弹性。当开窗211内连接分支管40时,所述支撑环能紧贴于所述分支管40的外表面上,以防止分支管40与所述主体管21相接处发生内漏。所述支撑件214由记忆合金所制,优选镍钛合金。Preferably, the support member 214 is a support ring extending along the edge of the window 211, and the support ring has elasticity. When the branch pipe 40 is connected in the window opening 211, the support ring can be closely attached to the outer surface of the branch pipe 40 to prevent internal leakage at the junction of the branch pipe 40 and the main body pipe 21. The support 214 is made of memory alloy, preferably nickel-titanium alloy.
本实施例中,所述主体覆膜210于所述开窗211的四周设置有显影结构215,所述显影结构215为设置于所述主体覆膜210上沿所述开窗211的边缘连续或间断排列的多个显影点。这些显影点可通过缝合、冲压、镶设或贴设的方式固定在主体覆膜210上。这些显影点沿所述开窗211的四周边缘至少设置一圈。显影结构215的材料可以采用不透X射线性能好、耐腐蚀性强、生物相容性好的材料制成。显影件材料包括但不限于金、铂、钽、锇、铼、钨、铱、铑等材料或这些金属的合金或复合物。本实施例中,所述显影点是含钽的镍钛合金金属片。这些显影点围成的环形与开窗211的形状一致,因此,这些显影点围成连接或间断的环状显影机构,在手术过程中通过影像设备能清楚地观察出显影结构215的位置,即,能观察到所述开窗211附近的显影点是围绕所述开窗211的边缘的一圈的环状显影机构,因此,更方便快捷的在所述内嵌分支管25内插入分支管40的近端。In this embodiment, the main body film 210 is provided with a developing structure 215 around the window 211. The developing structure 215 is provided on the main body film 210 continuously or along the edge of the window 211. Multiple development points arranged intermittently. These developing points can be fixed on the main body cover film 210 by sewing, stamping, setting or sticking. These developing points are arranged at least once along the peripheral edges of the window 211. The material of the developing structure 215 may be made of a material with good X-ray opacity, strong corrosion resistance and good biocompatibility. Materials of the developing member include, but are not limited to, gold, platinum, tantalum, osmium, rhenium, tungsten, iridium, rhodium and other materials or alloys or composites of these metals. In this embodiment, the developing point is a nickel-titanium alloy metal sheet containing tantalum. The ring formed by these developing points is consistent with the shape of the window 211. Therefore, these developing points form a connected or intermittent ring-shaped developing mechanism. During the operation, the position of the developing structure 215 can be clearly observed by the imaging device, that is, It can be observed that the developing point near the window opening 211 is a ring-shaped developing mechanism around the edge of the window opening 211, therefore, it is more convenient and quick to insert the branch tube 40 in the embedded branch tube 25 The near end.
如图7a所示,在其他实施例中,显影结构215为连续或间断缠绕于所述支撑件214上的显影丝。所述显影丝可以采用含钽的镍钛合金金属丝,所述镍钛合金金属丝的直径为0.10-0.40mm。由于显影结构215具有显影性且为环状,在手术过程中通过影像设备能清楚地观察出显影结构215的位置,即,能观察至所述显影结构215是围绕所述开窗211的边缘一围的环状显影结构,而不是零散的显影点,因此,更方便快捷的在所述内嵌分支管25插入分支管40。As shown in FIG. 7a, in other embodiments, the developing structure 215 is a developing wire wound continuously or intermittently on the support member 214. The developing wire may be a nickel-titanium alloy wire containing tantalum, and the diameter of the nickel-titanium alloy wire is 0.10-0.40 mm. Since the developing structure 215 is developable and ring-shaped, the position of the developing structure 215 can be clearly observed through the imaging device during the operation, that is, the developing structure 215 can be observed around the edge of the window 211 The surrounding annular developing structure is not a scattered developing point. Therefore, it is more convenient and quick to insert the branch pipe 25 into the branch pipe 40.
如图7b所示,在其他实施例中,所述显影结构215为连续或者间断固定在支撑件214上的显影点,所述显影点通过缝合、冲压、热压、镶设或贴设的方式固定在支撑件214上。这些显影点围绕所述支撑件214设置至少一圈。As shown in FIG. 7b, in other embodiments, the developing structure 215 is a developing point that is continuously or intermittently fixed on the supporting member 214, and the developing point is stitched, stamped, hot-pressed, set or pasted. It is fixed on the support 214. These developing points are arranged at least once around the supporting member 214.
在其他实施例中,所述支撑件214为掺有显影材料的合金所制成,显影结构215是融合在所述支撑件214内的显影材料。所述支撑件214由含钽的镍钛合金丝围成,所述支撑件214的丝径为0.10-0.40mm。由于所述支撑件214上由含有显影材料的合金所制,因此, 所述支撑件214可以直接当作显影结构,无需在所述支撑件214上另外设置显影结构。在手术过程中通过影像设备能清楚地观察出支撑件214的位置,能方便快捷地在所述开窗211内插入分支管40,使用方便。In other embodiments, the supporting member 214 is made of an alloy mixed with a developing material, and the developing structure 215 is a developing material fused into the supporting member 214. The support member 214 is surrounded by a nickel-titanium alloy wire containing tantalum, and the wire diameter of the support member 214 is 0.10-0.40 mm. Since the supporting member 214 is made of an alloy containing a developing material, the supporting member 214 can be directly used as a developing structure, and no additional developing structure needs to be provided on the supporting member 214. During the operation, the position of the support 214 can be clearly observed through the imaging equipment, and the branch tube 40 can be inserted into the window 211 conveniently and quickly, which is convenient to use.
在其他实施例中,所述支撑件214的外表面上可以镶设有至少一周的镍钛合金金属丝,或在支撑件214的外表面上粘贴至少一周镍钛合金金属丝。优选地,所述支撑件214上缠绕钽丝。In other embodiments, the outer surface of the support member 214 may be inlaid with a nickel titanium alloy wire for at least one week, or the outer surface of the support member 214 may be pasted with a nickel nickel alloy wire for at least one week. Preferably, tantalum wire is wound on the support 214.
请参阅图8,图8是本申请第二实施例提供的内嵌分支支架的结构示意图。本申请第二实施例提供的内嵌分支支架的结构与第一实施例的结构相似,不同之处在于:在第二实施例中,所述内嵌分支管25的近端和/或远端的管口处设置有支撑环256,支撑环256用于撑开所述内嵌分支覆膜253,使所述内嵌分支覆膜253保持展开状态,方便分支管40的插入。支撑环256是沿所述内嵌分支覆膜253的近端或远端的开口处的边缘延伸,支撑环256适应所述内嵌分支管25的横截面的边缘形状,具体的,所述支撑环256可以为圆形、椭圆形或棱形。所述支撑环256具有弹性,当开窗211内需连接分支管40时,支撑环256能紧贴于所述分支管40的外表面,以防止分支管40与所述内嵌分支管25相接处发生内漏。所述支撑环256由记忆合金所制,优选镍钛合金。Please refer to FIG. 8, which is a schematic structural diagram of an in-line branch support provided by a second embodiment of the present application. The structure of the embedded branch stent provided in the second embodiment of the present application is similar to the structure of the first embodiment, except that in the second embodiment, the proximal end and/or the distal end of the embedded branch tube 25 A support ring 256 is provided at the nozzle of the tube, and the support ring 256 is used to expand the embedded branch coating 253, so that the embedded branch coating 253 can be kept in an unfolded state to facilitate insertion of the branch tube 40. The support ring 256 extends along the edge of the opening at the proximal end or the distal end of the embedded branch film 253, and the support ring 256 adapts to the edge shape of the cross section of the embedded branch tube 25. Specifically, the support The ring 256 may be circular, elliptical or prismatic. The support ring 256 has elasticity. When the branch pipe 40 needs to be connected in the window 211, the support ring 256 can be closely attached to the outer surface of the branch pipe 40 to prevent the branch pipe 40 from connecting with the embedded branch pipe 25 An internal leak occurred. The support ring 256 is made of memory alloy, preferably nickel titanium alloy.
所述内嵌分支管25的近端和/或远端的设置有环状显影部,所述环状显影部是围绕所述内嵌分支管25的周向设置至少一圈。所述环状显影部可以设置于所述内嵌分支覆膜253的近端和/或远端的开口处的边缘,所述环状显影部也可以是设置于内嵌分支管25的支撑环256。所述环状显影部设置于支撑环256上包括但不限于如下几种:在每一支撑环256上连接或间断地缠绕有显影丝,例如含钽的镍钛合金金属丝,所述镍钛合金金属丝的直径为0.10-0.40mm;由于支撑环256上的显影丝具有显影性且为环状,从而形成环状显影部;在手术过程中通过影像设备能清楚地观察出支撑环256上显影丝的位置,以方便快捷的在所述内嵌分支管25插入分支管40。其次,在每一支撑环256上连续或者间断固定有显影点,这些显影点围成环状显影部,这些显影点通过缝合、冲压、热压、镶设或贴设的方式固定在支撑环256上。另外,每一支撑环256也可以由掺有显影材料的合金所制成,例如由含钽的镍钛合金金属丝,从而使支撑环256本身就形成环状显影部。A ring-shaped developing portion is provided at the proximal end and/or the distal end of the embedded branch tube 25, and the ring-shaped developing portion is disposed at least once around the circumference of the embedded branch tube 25. The ring-shaped developing part may be provided at the edge of the opening of the proximal end and/or the distal end of the in-line branching film 253, and the ring-shaped developing part may also be a support ring provided in the inline branching tube 25 256. The ring-shaped developing portion is provided on the support ring 256 and includes but is not limited to the following: a development wire, such as a nickel-titanium alloy wire containing tantalum and a nickel-titanium wire, is connected or intermittently wound on each support ring 256 The diameter of the alloy wire is 0.10-0.40mm; the developing wire on the support ring 256 has developability and is ring-shaped, thereby forming a ring-shaped developing portion; the support ring 256 can be clearly observed by the imaging device during the operation The position of the developing wire can be inserted into the branch pipe 40 in the embedded branch pipe 25 conveniently and quickly. Secondly, there are continuous or intermittently fixed development points on each support ring 256. These development points surround a ring-shaped development section, and these development points are fixed to the support ring 256 by sewing, stamping, hot pressing, setting or pasting. on. In addition, each supporting ring 256 may also be made of an alloy doped with a developing material, for example, a nickel-titanium alloy wire containing tantalum, so that the supporting ring 256 itself forms an annular developing portion.
请参阅图9,图9是本申请第三实施例提供的内嵌分支支架的结构示意图。本申请第三实施例提供的内嵌分支支架的结构与第一实施例的结构相似,不同之处在于:在第三实施例中,所述主体管21的主体支撑骨架212于开窗211的近端和/或远端处设置有小波形的支撑部2122,所述支撑部2122用于更好的撑开所述开窗211。Please refer to FIG. 9, which is a schematic structural diagram of an in-line branch bracket provided in a third embodiment of the present application. The structure of the embedded branch bracket provided in the third embodiment of the present application is similar to the structure of the first embodiment, except that in the third embodiment, the main body support frame 212 of the main body tube 21 is located on the window 211 A support portion 2122 with a small waveform is provided at the proximal end and/or the distal end, and the support portion 2122 is used to better prop up the window 211.
具体的,所述支撑部2122设置于邻近所述开窗211的环状波形支撑杆2120的波峰和/或波谷上,使所述支撑部2122位于所述开窗211的近端和/或远端。当所述支撑部2122设置于环状波形支撑杆2120的波峰上时,所述支撑部2122包括邻近所述开窗211边缘的波谷2124、位于所述波谷2124相对的两端的连接杆2128,以及连接于每一连接杆2128远离所述波谷2124的一端与对应的环状波形支撑杆2120的连接杆2125连接的波峰2126。由于所述波谷2124及两个波峰2126均邻近所述开窗211的近端,因此,所述支撑部2122能更好地撑开所述开窗211,从而减少所述开窗211的变形,方便在所述开窗211内插入分支管40。Specifically, the support portion 2122 is disposed on the crest and/or trough of the annular wave-shaped support rod 2120 adjacent to the window opening 211, so that the support portion 2122 is located at the proximal end and/or far away of the window opening 211 end. When the support portion 2122 is disposed on the crest of the annular wave-shaped support rod 2120, the support portion 2122 includes a trough 2124 adjacent to the edge of the window 211, connecting rods 2128 at opposite ends of the trough 2124, and A wave peak 2126 connected to an end of each connecting rod 2128 away from the trough 2124 and connected to the connecting rod 2125 of the corresponding annular waveform support rod 2120. Since the wave trough 2124 and the two wave crests 2126 are both near the proximal end of the window 211, the support portion 2122 can better support the window 211, thereby reducing the deformation of the window 211, It is convenient to insert the branch pipe 40 in the window 211.
如图10所示,图10是本申请第四实施例提供的血管支架的内嵌分支支架的结构示意图。本申请第四实施例提供的内嵌分支支架的结构与第三实施例的结构相似,不同之处在于:在第四实施例中,所述主体管21的主体支撑骨架212于开窗211的远端处也设置有小波形的支撑部,所述支撑部设置于邻近所述开窗211的环状波形支撑杆2120的波谷上。具体的,所述支撑部包括邻近所述开窗211远缘的波峰2126a、位于所述波峰2126a相对的两端的连接杆2128a,以及连接于每一连接杆2128a远离所述波峰2126a的一端与对应 的环状波形支撑杆2120的连接杆2125连接的波谷2124a。由于所述波峰2126a及两个波谷2124a均邻近所述开窗211,因此,所述支撑部能更好地撑开所述开窗211,减少所述开窗211的变形。As shown in FIG. 10, FIG. 10 is a schematic structural diagram of an embedded branch stent of a vascular stent provided in a fourth embodiment of the present application. The structure of the in-line branch bracket provided by the fourth embodiment of the present application is similar to the structure of the third embodiment, except that in the fourth embodiment, the main body support frame 212 of the main body pipe 21 is located at the window 211 A supporting portion with a small waveform is also provided at the distal end, and the supporting portion is disposed on the wave valley of the annular waveform supporting rod 2120 adjacent to the window 211. Specifically, the support portion includes a peak 2126a adjacent to the far edge of the window 211, connecting rods 2128a located at opposite ends of the peak 2126a, and an end connected to each connecting rod 2128a away from the peak 2126a and corresponding to The trough 2124a is connected to the connecting rod 2125 of the annular wave-shaped support rod 2120. Since the wave crest 2126a and the two wave troughs 2124a are both adjacent to the window opening 211, the supporting portion can better support the window opening 211 and reduce the deformation of the window opening 211.
以上是本申请实施例的实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本申请实施例原理的前提下,还可以做出若干改进和润饰,这些改进和润饰也视为本申请的保护范围。The above are the implementation manners of the embodiments of the present application. It should be noted that for those of ordinary skill in the art, without departing from the principle of the embodiments of the present application, several improvements and retouches can be made. It is regarded as the scope of protection of this application.

Claims (20)

  1. 一种内嵌分支支架,其包括主体管,所述主体管包括主体覆膜,其特征在于,所述主体覆膜上开设有至少一开窗,所述内嵌分支支架还包括设置于所述主体管的内腔的至少一内嵌分支管,至少一所述内嵌分支管自至少一所述开窗朝所述主体管的内腔延伸,所述内嵌分支管的轴线与主体管的轴线之间的角度大于0度。An in-line branch support includes a main body tube, and the main body tube includes a main body covering film, wherein the main body covering film is provided with at least one window, and the in-line branch support further includes a At least one embedded branch tube of the inner cavity of the main body tube, at least one of the embedded branch tubes extending from the at least one window to the inner cavity of the main body tube, the axis of the embedded branch tube and the main body tube The angle between the axes is greater than 0 degrees.
  2. 根据权利要求1所述的内嵌分支支架,其特征在于,所述内嵌分支管的轴线与主体管的轴线之间的角度为5度、45度或5度~45度的范围内的值。The in-line branch bracket according to claim 1, wherein the angle between the axis of the in-line branch tube and the axis of the main body tube is a value within a range of 5 degrees, 45 degrees, or 5 degrees to 45 degrees .
  3. 根据权利要求1或2任一所述的内嵌分支支架,其特征在于,所述内嵌分支管包括连接于所述开窗的内嵌分支覆膜,所述内嵌分支覆膜与所述主体覆膜上邻近所述开窗的部分密封连接。The in-line branch stent according to any one of claims 1 or 2, wherein the in-line branch tube includes an in-line branch film connected to the window, the in-line branch film and the The portion of the main body film adjacent to the window opening is hermetically connected.
  4. 根据权利要求3所述的内嵌分支支架,其特征在于,所述内嵌分支覆膜为管状形,所述内嵌分支覆膜的近端密封连接于所述开窗的边缘。The in-line branch stent according to claim 3, wherein the in-line branch film is tubular, and the proximal end of the in-line branch film is sealingly connected to the edge of the window.
  5. 根据权利要求3所述的内嵌分支支架,其特征在于,所述内嵌分支覆膜的内周面或外周面上设置有弹性的内嵌分支骨架。The in-line branch stent according to claim 3, wherein an elastic in-line branch skeleton is provided on an inner peripheral surface or an outer peripheral surface of the in-line branch film.
  6. 根据权利要求3所述的内嵌分支支架,其特征在于,所述内嵌分支管与所述开窗之间连接有过渡覆膜,所述过渡覆膜的远端密封连接于所述开窗的边缘,所述过渡覆膜的近端连接于所述内嵌分支管。The in-line branch stent according to claim 3, wherein a transition coating is connected between the in-line branch tube and the window, and a distal end of the transition coating is sealingly connected to the window , The proximal end of the transition membrane is connected to the embedded branch tube.
  7. 根据权利要求6所述的内嵌分支支架,其特征在于,所述过渡覆膜呈圆锥形环状,所述过渡覆膜的近端的外径大于远端的外径。The in-line branched stent according to claim 6, wherein the transitional membrane has a conical ring shape, and the outer diameter of the proximal end of the transitional membrane is greater than the outer diameter of the distal end.
  8. 根据权利要求6所述的内嵌分支支架,其特征在于,所述过渡覆膜的远端的截面相对于开窗向内凹以形成导引部。The in-line branch stent according to claim 6, wherein the cross-section of the distal end of the transition membrane is recessed inward with respect to the window to form a guide portion.
  9. 根据权利要求6所述的内嵌分支支架,其特征在于,所述过渡覆膜的内周面或外周面上设置有弹性的支撑骨架。The in-line branched stent according to claim 6, wherein an elastic support skeleton is provided on the inner peripheral surface or outer peripheral surface of the transition coating.
  10. 根据权利要求6所述的内嵌分支支架,其特征在于,所述内嵌分支管包括连接于所述过渡覆膜的支撑骨架。The in-line branch stent according to claim 6, wherein the in-line branch pipe includes a support frame connected to the transitional membrane.
  11. 根据权利要求10所述的内嵌分支支架,其特征在于,所述内嵌分支管还包括贴合于所述支撑骨架的内周面或处周面上的内嵌分支覆膜。The in-line branch stent according to claim 10, wherein the in-line branch tube further comprises an in-line branch film adhered to an inner peripheral surface or a peripheral surface of the support frame.
  12. 根据权利要求1所述的内嵌分支支架,其特征在于,所述开窗的边缘设置有支撑件,所述支撑件用于撑开所述开窗,以使开窗保持开口状态。The in-line branching bracket according to claim 1, wherein a support member is provided at an edge of the window opening, and the support member is used to prop up the window opening to keep the window opening state.
  13. 根据权利要求12所述的内嵌分支支架,其特征在于,所述支撑件是沿所述开窗的边缘延伸的支撑环,所述支撑环为圆形、椭圆形或梭形结构。The in-line branch support according to claim 12, wherein the support member is a support ring extending along the edge of the window, and the support ring has a circular, elliptical or shuttle-shaped structure.
  14. 根据权利要求13所述的内嵌分支支架,其特征在于,所述支撑环由含有显影材料的合金丝所制;或者所述支撑环上连续或间断地缠绕有显影丝;或者所述支撑环上连接或间断地设置有显影点。The in-line branch support according to claim 13, wherein the support ring is made of an alloy wire containing a developing material; or the support ring is continuously or intermittently wound with a developing wire; or the support ring The developing point is provided on the upper connection or intermittently.
  15. 根据权利要求1所述的内嵌分支支架,其特征在于,所述开窗的边缘设置有若干显影点。The in-line branch support according to claim 1, wherein a plurality of developing points are provided on the edge of the window.
  16. 根据权利要求1所述的内嵌分支支架,其特征在于,所述内嵌分支管的近端和/或远端的管口处设置有支撑环。The in-line branch stent according to claim 1, wherein a support ring is provided at a nozzle of a proximal end and/or a distal end of the in-line branch tube.
  17. 根据权利要求16所述的内嵌分支支架,其特征在于,所述支撑环由显影材料的合金丝所制;所述支撑环上连续或间断地缠绕有显影丝;或者所述支撑环上连接或间断地设置有显影点。The in-line branching bracket according to claim 16, wherein the support ring is made of an alloy wire of a developing material; the support ring is continuously or intermittently wound with a developing wire; or the support ring is connected Or the development point is set intermittently.
  18. 根据权利要求1所述的内嵌分支支架,其特征在于,所述内嵌分支管的近端和/或远端设置有环状显影部。The in-line branch stent according to claim 1, wherein a ring-shaped developing portion is provided at the proximal end and/or the distal end of the in-line branch tube.
  19. 根据权利要求1所述的内嵌分支支架,其特征在于,所述主体管还包括贴合于所 述主体覆膜的内周面或外周面的主体支撑骨架,所述主体支撑骨架于开窗的近端和/或远端设置有支撑部,所述支撑部用于撑开所述开窗。The in-line branched stent according to claim 1, wherein the main body tube further includes a main body support frame attached to the inner or outer circumferential surface of the main body film, and the main body support frame is used for window opening The proximal end and/or the distal end of is provided with a supporting portion, and the supporting portion is used to prop up the window opening.
  20. 一种血管支架,其特征在于,包括如权利要求1至19任一所述的内嵌分支支架,以及至少一分支管,所述分支管的近端穿过所述开窗插接于所述内嵌分支支架的内嵌分支管内。A blood vessel stent, characterized in that it includes the embedded branch stent according to any one of claims 1 to 19, and at least one branch tube, and a proximal end of the branch tube is inserted into the branch through the window The embedded branch tube of the embedded branch bracket.
PCT/CN2019/121440 2018-11-28 2019-11-28 Intravascular stent and embedded branch stent thereof WO2020108547A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201811449123.8 2018-11-28
CN201821980894.5U CN209827101U (en) 2018-11-28 2018-11-28 Blood vessel stent and embedded branch stent thereof
CN201821980894.5 2018-11-28
CN201811449123.8A CN111227991A (en) 2018-11-28 2018-11-28 Blood vessel stent and embedded branch stent thereof

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