WO2020108547A1

WO2020108547A1 - Intravascular stent and embedded branch stent thereof

Info

Publication number: WO2020108547A1
Application number: PCT/CN2019/121440
Authority: WO
Inventors: 王永胜; 李安伟; 尹玉杨
Original assignee: 杭州唯强医疗科技有限公司
Priority date: 2018-11-28
Filing date: 2019-11-28
Publication date: 2020-06-04

Abstract

Provided is an intravascular stent (100), comprising an embedded branch stent (20), and at least one branch tube (40). The embedded branch stent (20) comprises a main body tube (21), the main body tube (21) comprises a main body coating (210), and at least one window (211) is provided in the main body coating (210). The embedded branch stent (20) further comprises at least one embedded branch tube (25) arranged in an inner cavity of the main body tube (21), and at least one embedded branch tube (25) extends toward the inner cavity of the main body tube (21) from the at least one window (211). The angle between the axis of the embedded branch tube (25) and the axis of the main body tube (21) is greater than 0 degrees. A proximal end of the branch tube (40) penetrates through the window (211) and is inserted into the embedded branch tube (25) of the embedded branch stent (20).

Description

Vascular stent and its embedded branch stent

Technical field

The present application relates to the technical field of implantable blood vessels, in particular to a blood vessel stent with an embedded branch stent, and an embedded branch stent of the blood vessel stent.

Background technique

Aortic aneurysm refers to the local or diffuse abnormal expansion of the aortic wall, which causes symptoms by compressing the surrounding organs. Aneurysm rupture is the main risk. It often occurs in the ascending aortic aortic arch, thoracic descending aorta, thoracic and abdominal aorta, and abdominal aorta. According to the structure, aortic aneurysms can be divided into true aortic aneurysms and false aortic aneurysms. Aortic aneurysms cause an increase in the medial pressure of the blood vessels, so they are progressively enlarged. If they develop for a long time, they eventually rupture, and the larger the tumor, the greater the possibility of rupture. According to statistics, if no surgical treatment is performed, 90% of thoracic aortic aneurysms die within 5 years, and 3/4 of abdominal aortic aneurysms die within 5 years.

Aortic dissection is another serious aortic disease. Aortic dissection refers to the destruction of the media of the thoracic aorta, bleeding within the blood vessel wall, and blood entering between the media and the adventitia of the blood vessel wall. Due to the impact of blood flow, once the aortic dissection is formed, the tear can be extended in the direction of blood flow, the dissection and the false cavity can be enlarged, and the true cavity can be compressed. Therefore, the possible risks of patients with aortic dissection include: (1) the threat of complete rupture of the blood vessel. Once the blood vessel is completely ruptured, the mortality rate is extremely high; (2) the dissection gradually expands and compresses the true cavity to supply blood to the distal end cut back. In most cases, the aortic dissection secondary to the thoracic aortic aneurysm, or coexist with the aortic aneurysm. The British Oxford Vascular Disease Study shows that the incidence of aortic dissection in natural population is about 6/100,000 per year, with more men than women, with an average age of 63 years. The incidence of aortic dissection in my country is much higher than that in European and American countries, and the age of onset is relatively young.

Aortic aneurysm diseases may involve branched arteries. Once the branched artery is involved, it will be difficult to resolve through interventional methods. At present, arterial cavity treatment has been carried out at home and abroad, that is, a minimally invasive method is used to implant arterial grafts into the diseased artery through the vascular channel to treat arterial disease and improve blood supply, so as to achieve the purpose of treatment. The endoluminal artery stent graft is composed of a tubular rigid wire stent and an artificial blood vessel fixed on the outside of the stent. The tubular rigid wire stent is formed of a flexible rigid wire that is folded in a Z shape to form a ring. A ring-shaped rigid wire and artificial blood vessel are sutured or bonded together to form a tubular stent graft. When in use, the tubular stent graft is compressed axially and loaded into the conveyor, which is delivered to the diseased artery through the smaller femoral artery, iliac artery, and brachial artery and then released due to the elastic force of the wire stent The effect is automatically restored to a straight tube and closely adheres to the inner wall of the aorta, isolating the artery lesion from the blood flow, thereby achieving the purpose of treatment.

In the prior art, commonly used stents related to arterial branch therapy include chimney stents, integrated multi-branch stents, and window-type stents. These stents are limited by the structure of the stent and often need to be customized temporarily, especially for some connection angles are relatively small When the branch stent is connected to the main vessel and the branch vessel, the branch stent often has a large bending angle, which causes the branch stent to be squeezed by the main stent and become blocked.

Application content

The purpose of the present application is to provide an in-line branch stent capable of preventing endoleak, and a blood vessel stent provided with the in-line branch stent.

In order to solve the above technical problems, the present application provides an in-line branching bracket, which includes a main body tube, and the main body tube includes a main body covering film, at least one window is opened on the main body covering film, and the in-line branching support It also includes at least one in-line branch tube disposed in the inner cavity of the main body tube, at least one in-line branch tube extending from at least one window opening toward the inner cavity of the main body tube, the in-line branch tube The angle between the axis of and the axis of the main body tube is greater than 0 degrees.

The present application also provides a vascular stent including an in-line branch stent and at least one branch tube. The in-line branch stent includes a main body tube, and the main body tube includes a main body membrane, and the main body membrane is provided with at least one A window opening, the in-line branch bracket further includes at least one in-line branch tube disposed in an inner cavity of the main body tube, at least one in-line branch tube from at least one of the window opening toward the main body tube The inner cavity extends, and the angle between the axis of the embedded branch tube and the axis of the main body tube is greater than 0 degrees, and the proximal end of the branch tube is inserted into the inline branch support through the window opening Inside the branch pipe.

The embedded branch stent of the vascular stent provided by the present application includes a main body tube and at least one branch tube disposed in the lumen of the main body tube, an angle between the axis of the embedded branch tube and the axis of the main body tube is greater than 0 degrees . When the branch tube needs to be connected to the embedded branch bracket, insert the proximal end of the branch tube into the lumen of the embedded branch tube, the embedded branch tube can sealingly wrap the branch tube The outer peripheral surface of the proximal end can effectively prevent internal leakage and facilitate the insertion of the branch tube on the embedded branch bracket. In addition, since the angle between the axis of the embedded branch tube and the axis of the main body tube is greater than 0 degrees, the branch tube is obliquely connected to the main body tube, which can prevent the branch tube from being released into the branch blood vessel Afterwards, the branch pipe is prevented from being blocked due to bending caused by being squeezed due to excessive bending at the connection with the main body pipe.

BRIEF DESCRIPTION

In order to more clearly explain the technical solutions in the embodiments of the present application, the following will briefly introduce the drawings required in the embodiments. Obviously, the drawings in the following description are only some embodiments of the present application. For those of ordinary skill in the art, without paying any creative work, other obvious deformation methods can be obtained according to these drawings.

FIG. 1 is a schematic structural diagram of a vascular stent provided in the first embodiment of the present application.

FIG. 2 is a schematic structural diagram of the in-line branch bracket in FIG. 1.

FIG. 3 is a schematic perspective view of the ring-shaped wave supporting rod in FIG. 2.

FIG. 4 is a schematic view of the structure of the ring-shaped wave supporting rod in FIG. 1 connected to the main body film.

5a-5c are structural schematic diagrams of other forms of an embedded branch tube with an embedded branch bracket of the present application.

6 is an enlarged view of the proximal end portion of the in-line branch stent in FIG. 1.

7a and 7b are schematic diagrams of different development structures around the window of the embedded branching bracket of the present application.

FIG. 8 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a second embodiment of the present application.

9 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a third embodiment of the present application.

10 is a schematic structural diagram of an in-line branch stent of a blood vessel stent provided in a fourth embodiment of the present application.

detailed description

The technical solutions in the embodiments of the present application will be described clearly and completely in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, but not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by a person of ordinary skill in the art without paying any creative work fall within the protection scope of the present application.

In addition, the descriptions of the following embodiments refer to additional drawings to illustrate specific embodiments that can be implemented by the present application. Directional terms mentioned in this application, such as "upper", "lower", "front", "rear", "left", "right", "inner", "outer", "side", etc., only It refers to the directions of the attached drawings. Therefore, the direction terms are used for better and clearer explanation and understanding of the application, rather than indicating or implying that the device or element referred to must have a specific orientation, with a specific orientation The construction and operation cannot therefore be understood as a limitation of this application.

In the description of the present application, the “proximal end” in the present application refers to the end close to the position of the heart, and the “distal end” refers to the end far from the position of the heart. The high and low mentioned in this application are relative to the body tube coating. The end surface that exceeds the body tube coating is called high, and the one that does not exceed the body tube coating is called low. This definition is just for convenience of expression, and It cannot be understood as a limitation of this application.

Please refer to FIG. 1, which is a schematic structural diagram of a vascular stent provided in a first embodiment of the present application. The present application provides a vascular stent 100 including an embedded branch stent 20 and at least one branch tube 40. The in-line branching bracket 20 includes a main body tube 21 and at least one in-line branching tube 25. The main body tube 21 is of an equal-diameter structure or a non-equi-diameter structure. The main body tube 21 includes a tubular main body film 210, and at least one of the embedded branch tubes 25 is disposed in the inner cavity of the main body tube 21 of the embedded branch bracket 20. At least one window 211 is provided on the main body film 210, and at least one embedded branch tube 25 extends from the at least one window 211 toward the inner cavity of the main body tube 21. The angle between the axis of the embedded branch pipe 25 and the axis of the main body pipe 21 is greater than 0 degrees. The proximal end of the branch pipe 40 is inserted into the inner cavity of the embedded branch pipe 25 of the embedded branch bracket 20 through the window 211, and the branch pipe 40 is hermetically sleeved with the embedded branch pipe 25 The near end.

In this embodiment, the main body tube 21 has a non-equal-diameter structure. The proximal end diameter of the main body pipe 21 is larger than the distal end diameter, and the diameter of the main body pipe 21 tapers from the proximal end to the distal end.

Specifically, the main body coating 210 is a tubular structure, and the shape of the lateral end surface is a circle, an ellipse, or a prism that matches the blood vessel. At least one of the window openings 211 is opened on the tubular film. The window openings 211 may be circular holes, elliptical holes, prismatic holes, or irregular curved surfaces. The main body film 210 is made of polyester cloth, PTFE, PET or other polymer materials.

The embedded branch stent 20 and the branch tube 40 are both self-expanding stents. When the embedded branch stent 20 or the branch tube 40 is delivered through the sheath tube, the embedded branch stent 20 or the branch The diameter of the tube 40 can be reduced to a smaller state for delivery in the sheath; when the embedded branch stent 20 or the branch tube 40 is released in the blood vessel, the embedded branch stent 20 or the branch tube 40 It can be automatically expanded to the required shape and size, so that the embedded branch stent 20 or the branch tube 40 can be supported on the inner wall of the vascular lesion, and the embedded branch stent 20 or the branch tube 40 The inner wall of the blood vessel produces radial support, which can rebuild the blood vessel.

The embedded branch stent 20 of the vascular stent 100 of the present application includes a main body tube 21 and at least one branch tube 40 disposed in the lumen of the main body tube 21, the axis of the embedded branch tube 25 and the axis of the main body tube 21 The angle between is greater than 0 degrees. When the branch tube 40 needs to be connected to the embedded branch bracket 20, insert the proximal end of the branch tube 40 into the inner cavity of the embedded branch tube 25, the embedded branch tube 25 can be sealed The outer peripheral surface of the proximal end of the branch tube 40 is wrapped, so as to effectively prevent the internal leakage of the connection position of the branch tube 40 and the embedded branch bracket 20, and facilitate the insertion of the branch tube 40 on the embedded branch bracket 20. In addition, since the angle between the axis of the embedded branch pipe 25 and the axis of the main body pipe 21 is greater than 0 degrees, the branch pipe 40 is obliquely connected to the main body pipe 21, which prevents the branch pipe 40 from After being released to the branch blood vessel, it is bent due to being squeezed due to excessive bending amplitude, thereby preventing the branch tube 40 from being blocked.

Preferably, the angle between the axis of the inline branch pipe 25 and the axis of the main body pipe 21 is a value within a range of 5 degrees, 45 degrees, or 5 degrees to 45 degrees. Specifically, when the main body tube 21 and the embedded branch pipe 25 are in an extended state, the embedded branch pipe 25 is obliquely connected to the main body pipe 21, that is, the axis of the embedded branch pipe 25 and the main body pipe The angle between the axes of 21 is a value in the range of 5 degrees, 45 degrees, or 5 degrees to 45 degrees. When the proximal end of the branch pipe 40 is inserted into the embedded branch pipe 25, the axis of the proximal end of the branch pipe 40 coincides with the axis of the embedded branch pipe 25, so that the branch pipe 40 It is connected to the main body tube 21 obliquely.

In other embodiments, the angle between the axis of the inline branch pipe 25 and the axis of the main body pipe 21 can be selected according to need.

The axial extension length of the embedded branch pipe 25 is greater than or equal to 2 mm. Preferably, the axial extension length of the embedded branch pipe 25 is a value in the range of 2 mm, 100 mm, or 2 mm to 100 mm. The inner diameter of the embedded branch pipe 25 is greater than or equal to 2 mm. Preferably, the inner diameter of the embedded branch pipe is a value in the range of 2 mm, 5 mm, or 2 mm to 5 mm. The embedded branch pipe 25 serves as an anchor portion for connecting between the main body pipe 21 and the branch pipe 40. The longer the axial extension of the embedded branch pipe 25, the The longer the length of the sealable sleeve is, the more stable the proximal end portion of the branch tube 40 can be connected to the main body tube 21, thereby achieving a better leak-proof effect.

Please refer to FIG. 2 to FIG. 4 together. FIG. 2 is a schematic structural view of the in-line branch support in FIG. 1; FIG. 3 is a perspective structural schematic view of the annular wave-shaped support rod in FIG. 2; FIG. Schematic diagram of the structure of the corrugated support rod connected to the main body film. The main body tube 21 further includes a main body support frame 212 provided on the inner or outer circumferential surface of the main body film 210. Specifically, the main body support frame 212 is sewn to the main body film 210 by a suture. Inner peripheral surface or outer peripheral surface. The main body supporting framework 212 may be an elastic metal supporting framework or an elastic non-metallic supporting framework such as a polymer material. In this embodiment, the main body supporting framework 212 is a nickel alloy stent. When the main body supporting framework 212 is transported through the sheath, the diameter of the main body supporting framework 212 may be contracted to a smaller state for transport in the sheath; when When the main body supporting framework 212 is released in the blood vessel, the main body supporting framework 212 can automatically expand to the desired shape and size, so that the main body supporting framework 212 can be supported on the inner wall of the corresponding blood vessel.

The main body supporting framework 212 may be laser-cut with a nickel alloy tube, or may be woven with metal wires such as nickel alloy wires. The degree of density of the mesh structure of the main body supporting skeleton 212 is set as required. In this embodiment, the main body support frame 212 includes a plurality of Z-shaped or sinusoidal wave-shaped support rods 2120, and these ring-shaped support rods 2120 are arranged at intervals along the axial direction of the main body coating 210, that is, these rings The wave-shaped support rods 2120 are arranged in parallel with a gap from the proximal end to the distal end of the main body tube 21.

Each ring-shaped wave support bar 2120 may be a high-wave wave support bar or a high-low wave support bar, etc. The contour wave support bar means that the height of each wave peak on the ring-shaped wave support bar 2120 is the same, and the height of each wave valley is the same That is, the peaks and troughs are on the same plane. The high and low wave support bars mean that the heights of at least two wave peaks on the ring-shaped wave support bar 2120 are different, and/or the heights of at least two wave troughs are different. In this embodiment, the annular wave-shaped support rods 2120 of the main body tube 21 are all constant-wave support rods.

As shown in FIG. 3, each Z-shaped or sinusoidal waveform of each annular waveform support rod 2120 includes a peak 2121, a valley 2123, and a connecting rod 2125 connected between the peak 2121 and the valley 2123 . Each annular wave-shaped support rod 2120 is woven by a super-elastic nickel-titanium wire, and the selectable wire diameter (ie diameter) of the super-elastic nickel-titanium alloy wire is 0.2 mm to 0.55 mm. Each annular wave-shaped support rod 2120 is provided with a connection sleeve 2127 for connecting opposite ends of the superelastic nickel-titanium wire to form an annular wave-shaped support rod 2120, that is, superelastic Both ends of the nickel-titanium wire are accommodated in the connecting sleeve 2127, and then the two ends of the nickel-titanium wire are fixed inside the connecting sleeve 2127 by mechanical compression or welding.

In this embodiment, the annular wave-shaped support rod 2120 is braided with 0.4 mm diameter nickel-titanium wire, the number of Z-shaped or sinusoidal waves is 9, and the vertical height of the annular wave-shaped support rod 2120 is 8-15 mm.

In other embodiments, the main body supporting skeleton 212 may be a woven mesh structure or a cut mesh structure.

In other embodiments, the number of sine waves of the annular wave-shaped support rod 2120 may be determined according to needs, and the vertical height of the annular wave-shaped support rod 2120 may be any height.

As shown in FIG. 4, each ring-shaped wave support rod 2120 of the main body support frame 212 is sewn to the body film 210 by a suture 23, that is, the thread 23 can be along each ring-shaped wave support rod The wave shape of 2120 is accompanied by the entire main body supporting skeleton 212. The suture 23 can also be sutured to the main body covering film 210 by a plurality of unequally spaced stitching knots. The selection range of the diameter of the suture 23 is 0.05mm-0.25mm. Alternatively, the main body support frame 212 may be fixedly connected to the main body film 210 by hot pressing.

A transition film 251 is connected between the embedded branch pipe 25 and the window 211, and the transition film 251 is tubular or conical ring-shaped, and the shape of its lateral end surface and the shape of the window 211 Correspondingly, it can be circular, elliptical or prismatic. The transition film 251 extends from the window 211 toward the inner cavity of the main body tube 21. One end of the transition film 251 is hermetically connected to the edge of the window 211, and the other end of the transition film 251 is hermetically connected to the proximal end of the embedded branch tube 25. Specifically, the edge of the proximal end of the transition film 251 is sealingly connected to the edge of the main body film 210 at the window 211, and the edge of the distal end of the transition film 251 is sealingly connected to the inlay On the peripheral surface of the proximal end of the branch tube 25, the outer diameter of the proximal end of the transition coating 251 is greater than the outer diameter of the distal end. The transition film 251 is made of polyester cloth, PTFE, PET or other polymer materials. Since the transitional film 251 is connected between the embedded branch pipe 25 and the window 211, the transitional film 251 can be sealingly connected between the main body film 210 and the embedded branch pipe 25, therefore, the The transition film 251 can prevent internal leakage between the embedded branch pipe 25 and the window 211.

In another embodiment, the outer diameter of the distal end of the transition coating 251 is greater than the outer diameter of the proximal end, so that the transition coating forms an inner recess, and the inner recess has a guiding effect. Or the cross-section of the distal end of the transition film 251 is recessed inward relative to the window opening to form a guide portion, so that the connection of the branch pipe 40 and the embedded branch pipe 25 is smoother.

In this embodiment, the proximal end of the transition film 251 is stitched to the main body film 210 at the edge of the window 211 by a suture, and the distal end of the transition film 251 is stitched to the inside by a stitch The proximal end of the branch tube 25 is embedded. The distal end of the transition membrane 251 may be an integral structure with the proximal end of the embedded branch tube 25.

In other embodiments, the connection between the proximal end of the transition coating 251 and the main body coating 210 may be connected by medical glue, and the distal end of the transition coating 251 and the embedded branch tube 25 The connection can also be via medical glue.

In other embodiments, a support skeleton may be provided on the transition coating 251 to stretch the transition coating 251. The support frame may be stitched to the inner peripheral surface or the outer peripheral surface of the transition coating 251 by a suture.

The embedded branch pipe 25 includes a tubular shaped embedded branch coating 253 and a support frame 255 provided on the embedded branch coating 253, that is, the inner or outer peripheral surfaces of the support frame 255 are bonded together There is the embedded branch film 253. Specifically, the support frame 255 is fixed between the inner peripheral surface or the outer peripheral surface of the embedded branch coating 253 or the multilayer coating by means of stitching or hot pressing. The shape of the lateral end surface of the embedded branch coating 253 is a circle, an ellipse, or a prism matching the proximal end of the branch tube 40. The proximal end of the embedded branch coating 253 is connected to the transition coating 251. remote. The distal end of the embedded branch membrane 253 extends toward the inner cavity of the main body tube 21. In the extended state, the angle between the axis of the embedded branch film 253 and the axis of the main body tube 21 is greater than 0 degrees. The main body film 210 is made of polyester cloth, PTFE, PET or other polymer materials.

The supporting framework 255 may be an elastic metal supporting framework or an elastic non-metallic supporting framework such as a polymer material. In this embodiment, the support frame 255 is a nickel alloy stent. When the support frame 255 is transported through the sheath tube, the diameter of the support frame 255 can be contracted to a smaller state for transportation in the sheath tube; when the support frame When 255 is released, the support frame 255 can automatically expand to the desired shape and size. The support frame 255 can support the embedded branch coating film 253 to keep the embedded branch coating film 253 in an open state, which is convenient for the connection of the branch tube 40.

The support frame 255 may be laser-cut with a nickel alloy tube, or may be woven with metal wires such as nickel alloy wires. The degree of density of the mesh structure supporting the skeleton 255 is set as required. In this embodiment, the support frame 255 includes a plurality of Z-shaped or sinusoidal ring-shaped wave-shaped support rods, and these ring-shaped wave-shaped support rods are arranged at intervals along the axial direction of the embedded branch coating 253, that is, these ring-shaped support rods The wave-shaped support rods are arranged in parallel gaps from the proximal end to the distal end of the embedded branch covering film 253 in sequence.

The inner diameter of the embedded branch tube 25 is less than or equal to the outer diameter of the proximal end of the branch tube 40. When the proximal end of the branch tube 40 is inserted into the embedded branch tube 25 through the window 211 and released, The support frame 255 squeezes the outer wall of the branch pipe 40 to make the connection of the branch pipe 40 and the embedded branch pipe 25 firmer, and to maintain the shape of the branch pipe 40 entering the embedded branch pipe 25 The embedded branch covering film 253 is wrapped around the outer peripheral surface of the proximal end of the branch tube 40, so as to further prevent internal leakage.

Please refer to FIG. 5a to FIG. 5c together. FIG. 5a to FIG. 5c are schematic structural diagrams of other forms of the embedded branch tube with the embedded branch bracket of the present application. The support frame 255 of the embedded branch pipe 25 can be selected from any ring-shaped support frame as shown in FIGS. 5a and 5b or the mesh frame shown in FIG. 5c. The ring-shaped support frame includes a number of Z-shaped or sinusoidal wave-shaped ring-shaped support rods, which are arranged at intervals along the axial direction of the embedded branch pipe 25. The mesh skeleton may be woven or cut.

In other embodiments, the embedded branch tube 25 includes only the embedded branch coating 253, that is, the supporting frame 255 on the embedded branch coating 253 can be omitted, and the proximal end of the embedded branch coating 253 is connected to the transition coating The distal end of the membrane 251.

In other embodiments, the embedded branch pipe 25 only includes a support frame 255, that is, the embedded branch film 253 on the support frame 255 may be omitted, the support frame 255 is a bare support, and the bare support may be a braid Or cut the bare bracket of the structure. The proximal end of the bare stent is connected to the distal end of the transition membrane 251.

In other embodiments, the in-line branch tube 25 includes an in-line branch film 253 directly connected to the window 211. The in-line branch film 253 and the main body film 210 are adjacent to the window 211. For sealing connection, the embedded branch film 253 is used to wrap the proximal end of the branch tube 40. Specifically, the transition film 251 between the embedded branch tube 25 and the window 211 may be omitted, but directly connected to the main body film through the proximal end of the embedded branch film 253 directly and sealingly 210 at the edge of the window 211. The embedded branch coating film 253 has a tubular structure, and the shape of the lateral end surface of the embedded branch coating film 253 is consistent with the shape of the window 211, and is specifically circular, elliptical, or prismatic. The embedded branch coating film 253 may be provided with an elastic embedded branch skeleton, and the embedded branch skeleton is attached to the inner peripheral surface or the outer peripheral surface of the embedded branch coating film 253. The embedded branch skeleton can make the connection of the branch pipe 40 connected in the embedded branch pipe 25 firmer, and can maintain the shape of the branch pipe 40 entering the embedded branch pipe 25. In other embodiments, the embedded branch skeleton on the embedded branch coating 253 may also be omitted.

As shown in FIG. 6, a support member 214 is provided at the edge of the window opening 211, and the support member 214 is used to support the window opening 211 to keep the window opening 211 open. The support member 214 is a support rod fixed to the edge of the window opening 211, the support rod extends along the edge of the window opening 211, the support rod adapts to the shape of the edge of the window opening 211, specifically, The support rod may have a circular, elliptical or prismatic ring structure.

Preferably, the support member 214 is a support ring extending along the edge of the window 211, and the support ring has elasticity. When the branch pipe 40 is connected in the window opening 211, the support ring can be closely attached to the outer surface of the branch pipe 40 to prevent internal leakage at the junction of the branch pipe 40 and the main body pipe 21. The support 214 is made of memory alloy, preferably nickel-titanium alloy.

In this embodiment, the main body film 210 is provided with a developing structure 215 around the window 211. The developing structure 215 is provided on the main body film 210 continuously or along the edge of the window 211. Multiple development points arranged intermittently. These developing points can be fixed on the main body cover film 210 by sewing, stamping, setting or sticking. These developing points are arranged at least once along the peripheral edges of the window 211. The material of the developing structure 215 may be made of a material with good X-ray opacity, strong corrosion resistance and good biocompatibility. Materials of the developing member include, but are not limited to, gold, platinum, tantalum, osmium, rhenium, tungsten, iridium, rhodium and other materials or alloys or composites of these metals. In this embodiment, the developing point is a nickel-titanium alloy metal sheet containing tantalum. The ring formed by these developing points is consistent with the shape of the window 211. Therefore, these developing points form a connected or intermittent ring-shaped developing mechanism. During the operation, the position of the developing structure 215 can be clearly observed by the imaging device, that is, It can be observed that the developing point near the window opening 211 is a ring-shaped developing mechanism around the edge of the window opening 211, therefore, it is more convenient and quick to insert the branch tube 40 in the embedded branch tube 25 The near end.

As shown in FIG. 7a, in other embodiments, the developing structure 215 is a developing wire wound continuously or intermittently on the support member 214. The developing wire may be a nickel-titanium alloy wire containing tantalum, and the diameter of the nickel-titanium alloy wire is 0.10-0.40 mm. Since the developing structure 215 is developable and ring-shaped, the position of the developing structure 215 can be clearly observed through the imaging device during the operation, that is, the developing structure 215 can be observed around the edge of the window 211 The surrounding annular developing structure is not a scattered developing point. Therefore, it is more convenient and quick to insert the branch pipe 25 into the branch pipe 40.

As shown in FIG. 7b, in other embodiments, the developing structure 215 is a developing point that is continuously or intermittently fixed on the supporting member 214, and the developing point is stitched, stamped, hot-pressed, set or pasted. It is fixed on the support 214. These developing points are arranged at least once around the supporting member 214.

In other embodiments, the supporting member 214 is made of an alloy mixed with a developing material, and the developing structure 215 is a developing material fused into the supporting member 214. The support member 214 is surrounded by a nickel-titanium alloy wire containing tantalum, and the wire diameter of the support member 214 is 0.10-0.40 mm. Since the supporting member 214 is made of an alloy containing a developing material, the supporting member 214 can be directly used as a developing structure, and no additional developing structure needs to be provided on the supporting member 214. During the operation, the position of the support 214 can be clearly observed through the imaging equipment, and the branch tube 40 can be inserted into the window 211 conveniently and quickly, which is convenient to use.

In other embodiments, the outer surface of the support member 214 may be inlaid with a nickel titanium alloy wire for at least one week, or the outer surface of the support member 214 may be pasted with a nickel nickel alloy wire for at least one week. Preferably, tantalum wire is wound on the support 214.

Please refer to FIG. 8, which is a schematic structural diagram of an in-line branch support provided by a second embodiment of the present application. The structure of the embedded branch stent provided in the second embodiment of the present application is similar to the structure of the first embodiment, except that in the second embodiment, the proximal end and/or the distal end of the embedded branch tube 25 A support ring 256 is provided at the nozzle of the tube, and the support ring 256 is used to expand the embedded branch coating 253, so that the embedded branch coating 253 can be kept in an unfolded state to facilitate insertion of the branch tube 40. The support ring 256 extends along the edge of the opening at the proximal end or the distal end of the embedded branch film 253, and the support ring 256 adapts to the edge shape of the cross section of the embedded branch tube 25. Specifically, the support The ring 256 may be circular, elliptical or prismatic. The support ring 256 has elasticity. When the branch pipe 40 needs to be connected in the window 211, the support ring 256 can be closely attached to the outer surface of the branch pipe 40 to prevent the branch pipe 40 from connecting with the embedded branch pipe 25 An internal leak occurred. The support ring 256 is made of memory alloy, preferably nickel titanium alloy.

A ring-shaped developing portion is provided at the proximal end and/or the distal end of the embedded branch tube 25, and the ring-shaped developing portion is disposed at least once around the circumference of the embedded branch tube 25. The ring-shaped developing part may be provided at the edge of the opening of the proximal end and/or the distal end of the in-line branching film 253, and the ring-shaped developing part may also be a support ring provided in the inline branching tube 25 256. The ring-shaped developing portion is provided on the support ring 256 and includes but is not limited to the following: a development wire, such as a nickel-titanium alloy wire containing tantalum and a nickel-titanium wire, is connected or intermittently wound on each support ring 256 The diameter of the alloy wire is 0.10-0.40mm; the developing wire on the support ring 256 has developability and is ring-shaped, thereby forming a ring-shaped developing portion; the support ring 256 can be clearly observed by the imaging device during the operation The position of the developing wire can be inserted into the branch pipe 40 in the embedded branch pipe 25 conveniently and quickly. Secondly, there are continuous or intermittently fixed development points on each support ring 256. These development points surround a ring-shaped development section, and these development points are fixed to the support ring 256 by sewing, stamping, hot pressing, setting or pasting. on. In addition, each supporting ring 256 may also be made of an alloy doped with a developing material, for example, a nickel-titanium alloy wire containing tantalum, so that the supporting ring 256 itself forms an annular developing portion.

Please refer to FIG. 9, which is a schematic structural diagram of an in-line branch bracket provided in a third embodiment of the present application. The structure of the embedded branch bracket provided in the third embodiment of the present application is similar to the structure of the first embodiment, except that in the third embodiment, the main body support frame 212 of the main body tube 21 is located on the window 211 A support portion 2122 with a small waveform is provided at the proximal end and/or the distal end, and the support portion 2122 is used to better prop up the window 211.

Specifically, the support portion 2122 is disposed on the crest and/or trough of the annular wave-shaped support rod 2120 adjacent to the window opening 211, so that the support portion 2122 is located at the proximal end and/or far away of the window opening 211 end. When the support portion 2122 is disposed on the crest of the annular wave-shaped support rod 2120, the support portion 2122 includes a trough 2124 adjacent to the edge of the window 211, connecting rods 2128 at opposite ends of the trough 2124, and A wave peak 2126 connected to an end of each connecting rod 2128 away from the trough 2124 and connected to the connecting rod 2125 of the corresponding annular waveform support rod 2120. Since the wave trough 2124 and the two wave crests 2126 are both near the proximal end of the window 211, the support portion 2122 can better support the window 211, thereby reducing the deformation of the window 211, It is convenient to insert the branch pipe 40 in the window 211.

As shown in FIG. 10, FIG. 10 is a schematic structural diagram of an embedded branch stent of a vascular stent provided in a fourth embodiment of the present application. The structure of the in-line branch bracket provided by the fourth embodiment of the present application is similar to the structure of the third embodiment, except that in the fourth embodiment, the main body support frame 212 of the main body pipe 21 is located at the window 211 A supporting portion with a small waveform is also provided at the distal end, and the supporting portion is disposed on the wave valley of the annular waveform supporting rod 2120 adjacent to the window 211. Specifically, the support portion includes a peak 2126a adjacent to the far edge of the window 211, connecting rods 2128a located at opposite ends of the peak 2126a, and an end connected to each connecting rod 2128a away from the peak 2126a and corresponding to The trough 2124a is connected to the connecting rod 2125 of the annular wave-shaped support rod 2120. Since the wave crest 2126a and the two wave troughs 2124a are both adjacent to the window opening 211, the supporting portion can better support the window opening 211 and reduce the deformation of the window opening 211.

The above are the implementation manners of the embodiments of the present application. It should be noted that for those of ordinary skill in the art, without departing from the principle of the embodiments of the present application, several improvements and retouches can be made. It is regarded as the scope of protection of this application.

Claims

An in-line branch support includes a main body tube, and the main body tube includes a main body covering film, wherein the main body covering film is provided with at least one window, and the in-line branch support further includes a At least one embedded branch tube of the inner cavity of the main body tube, at least one of the embedded branch tubes extending from the at least one window to the inner cavity of the main body tube, the axis of the embedded branch tube and the main body tube The angle between the axes is greater than 0 degrees.
The in-line branch bracket according to claim 1, wherein the angle between the axis of the in-line branch tube and the axis of the main body tube is a value within a range of 5 degrees, 45 degrees, or 5 degrees to 45 degrees .
The in-line branch stent according to any one of claims 1 or 2, wherein the in-line branch tube includes an in-line branch film connected to the window, the in-line branch film and the The portion of the main body film adjacent to the window opening is hermetically connected.
The in-line branch stent according to claim 3, wherein the in-line branch film is tubular, and the proximal end of the in-line branch film is sealingly connected to the edge of the window.
The in-line branch stent according to claim 3, wherein an elastic in-line branch skeleton is provided on an inner peripheral surface or an outer peripheral surface of the in-line branch film.
The in-line branch stent according to claim 3, wherein a transition coating is connected between the in-line branch tube and the window, and a distal end of the transition coating is sealingly connected to the window , The proximal end of the transition membrane is connected to the embedded branch tube.
The in-line branched stent according to claim 6, wherein the transitional membrane has a conical ring shape, and the outer diameter of the proximal end of the transitional membrane is greater than the outer diameter of the distal end.
The in-line branch stent according to claim 6, wherein the cross-section of the distal end of the transition membrane is recessed inward with respect to the window to form a guide portion.
The in-line branched stent according to claim 6, wherein an elastic support skeleton is provided on the inner peripheral surface or outer peripheral surface of the transition coating.
The in-line branch stent according to claim 6, wherein the in-line branch pipe includes a support frame connected to the transitional membrane.
The in-line branch stent according to claim 10, wherein the in-line branch tube further comprises an in-line branch film adhered to an inner peripheral surface or a peripheral surface of the support frame.
The in-line branching bracket according to claim 1, wherein a support member is provided at an edge of the window opening, and the support member is used to prop up the window opening to keep the window opening state.
The in-line branch support according to claim 12, wherein the support member is a support ring extending along the edge of the window, and the support ring has a circular, elliptical or shuttle-shaped structure.
The in-line branch support according to claim 13, wherein the support ring is made of an alloy wire containing a developing material; or the support ring is continuously or intermittently wound with a developing wire; or the support ring The developing point is provided on the upper connection or intermittently.
The in-line branch support according to claim 1, wherein a plurality of developing points are provided on the edge of the window.
The in-line branch stent according to claim 1, wherein a support ring is provided at a nozzle of a proximal end and/or a distal end of the in-line branch tube.
The in-line branching bracket according to claim 16, wherein the support ring is made of an alloy wire of a developing material; the support ring is continuously or intermittently wound with a developing wire; or the support ring is connected Or the development point is set intermittently.
The in-line branch stent according to claim 1, wherein a ring-shaped developing portion is provided at the proximal end and/or the distal end of the in-line branch tube.
The in-line branched stent according to claim 1, wherein the main body tube further includes a main body support frame attached to the inner or outer circumferential surface of the main body film, and the main body support frame is used for window opening The proximal end and/or the distal end of is provided with a supporting portion, and the supporting portion is used to prop up the window opening.
A blood vessel stent, characterized in that it includes the embedded branch stent according to any one of claims 1 to 19, and at least one branch tube, and a proximal end of the branch tube is inserted into the branch through the window The embedded branch tube of the embedded branch bracket.