WO2020100693A1 - Heat exchanger - Google Patents

Heat exchanger Download PDF

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Publication number
WO2020100693A1
WO2020100693A1 PCT/JP2019/043552 JP2019043552W WO2020100693A1 WO 2020100693 A1 WO2020100693 A1 WO 2020100693A1 JP 2019043552 W JP2019043552 W JP 2019043552W WO 2020100693 A1 WO2020100693 A1 WO 2020100693A1
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WO
WIPO (PCT)
Prior art keywords
liquid chamber
temperature
filter
heat exchanger
port
Prior art date
Application number
PCT/JP2019/043552
Other languages
French (fr)
Japanese (ja)
Inventor
石原 和久
桑原 祐司
瑛一 小磯
Original Assignee
ニプロ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ニプロ株式会社 filed Critical ニプロ株式会社
Priority to JP2020555557A priority Critical patent/JPWO2020100693A1/en
Priority to BR112021007569-0A priority patent/BR112021007569A2/en
Publication of WO2020100693A1 publication Critical patent/WO2020100693A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3623Means for actively controlling temperature of blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits

Definitions

  • the present invention relates to a medical heat exchanger used for controlling the temperature of circulating fluid such as myocardial protection fluid and blood during surgery under cardiac arrest.
  • a means for cooling the myocardium for example, it is generally performed to cool the myocardium by lowering the temperature of circulating fluid such as blood or drug solution (for example, cardioplegic solution) and sending it to the coronary arteries of the heart.
  • circulating fluid such as blood or drug solution (for example, cardioplegic solution)
  • the temperature of the circulating fluid is controlled (cooled) by a heat exchanger connected to the coronary arteries of the heart.
  • the heat exchanger is, for example, like the medical heat exchanger (1) described in Japanese Patent No. 3742711 (Patent Document 1), the temperature of the circulating liquid by heat exchange between the circulating liquid and the heat exchange medium.
  • a bubble-trapping filter member (16) is provided in the biological circulation liquid circulation chamber (13) into which the temperature-controlled circulating liquid flows. Then, the circulating fluid that has passed through the bubble trapping filter member is fed into the body lumen (blood vessel) of the patient, whereby the myocardium is cooled by the circulating fluid.
  • the present invention has been made in view of the above circumstances, and a problem to be solved is to provide a heat exchanger having a novel structure capable of efficiently removing bubbles in a circulating liquid. is there.
  • the first aspect of the present invention is a heat exchanger including a heat exchange unit that adjusts the temperature of the circulating liquid, wherein the temperature-adjusted liquid into which the circulating liquid whose temperature has been adjusted in the heat exchange unit flows.
  • a chamber is provided, a filter for removing air in the circulating liquid is arranged in the temperature-adjusted liquid chamber, and a deaeration port is provided on the wall of the temperature-adjusted liquid chamber.
  • the filter is provided so as to be inclined toward the deaeration port.
  • the filter that allows the passage of the circulating liquid and restricts the passage of the air mixed with the circulating liquid is inclined toward the opening of the degassing port.
  • the air filtered by the filter is guided to the deaeration port by floating along the filter.
  • a second aspect of the present invention is the heat exchanger according to the first aspect, wherein the temperature-adjusted liquid chamber has a pre-degassing liquid chamber and a post-degassing liquid chamber on both sides of the filter.
  • the degassing port is provided on the wall of the pre-degassing liquid chamber.
  • the degassing port is provided in the wall portion of the pre-degassing liquid chamber, the degassing port is provided in the post-degassing liquid chamber. In comparison, it is possible to prevent air bubbles from entering the body and efficiently remove the air mixed with the circulating fluid.
  • a third aspect of the present invention is the heat exchanger according to the first or second aspect, in which the filter is insert-molded into a housing forming a wall of the temperature-adjusted liquid chamber. It is said that.
  • the filter is directly attached to the housing by insert molding, so that a separate member for fixing the filter to the housing is not required, and the number of parts is reduced. And the structure can be simplified.
  • a fourth aspect of the present invention is the heat exchanger according to any one of the first to third aspects, wherein the temperature detection port for measuring the temperature in the liquid chamber after temperature adjustment is the temperature adjustment port. It is provided on the wall of the rear liquid chamber.
  • the heat exchanger configured according to the present aspect, for example, when the temperature detection port itself projects into the liquid chamber after temperature adjustment, or a temperature sensor inserted into the temperature detection port projects into the liquid chamber after temperature adjustment. In this case, the problem that air bubbles are caught in the temperature detection port or the temperature sensor and remain will not easily occur.
  • a fifth aspect of the present invention is the heat exchanger according to any one of the first to fourth aspects, wherein at least the root portion of the degassing port is transparent.
  • the heat exchanger having the structure according to this aspect, it is possible to visually check the inside of the deaeration port from the outside, for example, after visually confirming the state where the air is accumulated in the deaeration port. It is also possible to discharge air to the outside by opening the opening / closing valve of the degassing port.
  • a sixth aspect of the present invention is the heat exchanger according to any one of the first to fifth aspects, in which the filter has a flat shape.
  • the heat exchanger having the structure according to this aspect, bubbles are efficiently guided to the degassing port without being caught in the filter. Moreover, even if the filter has a flat shape, it is possible to secure a sufficient filter area by providing the filter in a slanted manner, and secure the required flow rate of the circulating liquid while effectively removing air. be able to.
  • a seventh aspect of the present invention is the heat exchanger according to any one of the first to sixth aspects, in which the filter is made of a hydrophobic material.
  • the bubbles are easily moved along the filter, so that the bubbles are efficiently guided to the degassing port, so that the air discharge efficiency is improved.
  • An eighth aspect of the present invention is the heat exchanger according to any one of the first to sixth aspects, in which the filter is made of a hydrophilic material.
  • the circulating liquid can more easily pass through the filter.
  • a ninth aspect of the present invention is a heat exchanger including a heat exchange part for adjusting the temperature of the circulating liquid, wherein the temperature-adjusted liquid into which the circulating liquid whose temperature has been adjusted in the heat exchange part flows.
  • a chamber is provided, and a filter for removing air in the circulating liquid is disposed in the post-temperature-controlling liquid chamber, and both sides of the filter in the post-temperature-controlling liquid chamber are separated from the pre-degassing liquid chamber.
  • the filter is an after-effect liquid chamber, and the filter is an insert component member that is insert-molded into a housing that forms a wall portion of the temperature-adjusted liquid chamber.
  • the filter is directly attached to the housing by insert molding, so that a separate member for fixing the filter to the housing is not required, and the number of parts is reduced. And the structure can be simplified.
  • a tenth aspect of the present invention is the heat exchanger according to the ninth aspect, wherein the housing constitutes a wall portion of the pre-degassing liquid chamber and the post-degassing liquid.
  • a second liquid chamber wall member constituting a wall portion of the chamber, and the filter is attached to the first liquid chamber wall member of the housing.
  • the first liquid chamber wall member is provided with an opening connected to, for example, a heat exchange section, so that even if the filter is insert-molded, the mold can be formed after the molding. It is easy to remove and the housing with the filter is easily manufactured.
  • An eleventh aspect of the present invention is the heat exchanger according to any one of the first to tenth aspects, wherein the circulating liquid is communicated with the heat exchange section and introduces the circulating liquid into the heat exchange section.
  • a bottom member having an inlet port is provided, and a part of the bottom member facing the opening of the circulating liquid inlet port is provided with a flow dividing projection protruding toward the circulating liquid inlet port, Guide ridges extending in the circumferential direction of the bottom member are provided on both sides of the flow dividing projection in the circumferential direction of the bottom member.
  • the circulating liquid introduced from the circulating liquid inlet port to the inside of the bottom member is divided into both sides of the flow dividing protrusion by contacting the flow dividing protrusion, and the guide protrusions are provided.
  • the flow of the circulating liquid is divided into both sides in the circumferential direction by the flow dividing projections, the flow of the circulating liquid flows more smoothly inside the bottom member than in the case where there is no flow dividing protrusion, and thus the flow velocity of the circulating liquid decreases. For example, pressure loss is reduced. Therefore, the circulating liquid flowing from the circulating liquid inlet port to the inside of the bottom member smoothly flows to the heat exchanging portion, and the circulating liquid is efficiently supplied to the heat exchanging portion.
  • FIG. 1 The perspective view which shows the heat exchanger as the 1st Embodiment of this invention.
  • Bottom view of the heat exchanger shown in FIG. VI-VI sectional view of FIG. VII-VII sectional view of FIG. 1 is a perspective view of a bottom member constituting the heat exchanger shown in FIG.
  • An enlarged plan view of the bottom member shown in FIG. FIG. 10 is a cross-sectional view of the bottom member shown in FIG. 9, corresponding to the XX cross section of FIG. 9.
  • the figure which expands and shows the principal part of the heat exchanger shown in FIG. 1 is a perspective view of a second liquid chamber wall member that constitutes the heat exchanger shown in FIG. Enlarged sectional view of the second liquid chamber wall member shown in FIG.
  • the heat exchanger 10 is a surface heat exchanger in which the circulating liquid and the heat exchange medium are indirectly in contact with each other to exchange heat.
  • the heat exchange section 14 is housed in the housing 12. It has a different structure.
  • the vertical direction means the vertical direction in FIG. 2, which is the vertical vertical direction in principle.
  • the housing 12 is formed of a hard synthetic resin, and has a generally cylindrical housing body 16, a bottom member 18 that closes an opening on the lower side of the housing body 16, and a housing body 16. It is constituted by a lid member 20 that closes the upper opening.
  • the material for forming the housing 12 is not particularly limited, and may be metal or glass, but is preferably made of a synthetic resin such as polycarbonate or acrylic resin. It is desirable that the space is transparent or translucent so that the space can be visually confirmed. Further, the entire housing 12 does not need to be formed of the same material, and for example, the housing body 16, the bottom member 18, and the lid member 20 may be formed of different materials.
  • the housing main body 16 integrally includes a cylindrical housing tubular portion 22, and a heat exchange medium inlet port 24 and a heat exchange medium outlet port 26 that are connected to the peripheral wall portion of the housing tubular portion 22.
  • a heat exchange medium inlet port 24 and a heat exchange medium outlet port 26 are provided on the peripheral wall portion of the accommodating cylinder portion 22 as connection portions connected to an external device such as a blood reservoir.
  • Each of the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 has a substantially cylindrical shape, and extends from the lower portion of the storage tubular portion 22 toward both sides in the radial direction of the storage tubular portion 22, and Inclined toward the tip side.
  • both the inner cavity of the heat exchange medium inlet port 24 and the inner cavity of the heat exchange medium outlet port 26 are communicated with the inner cavity of the housing tubular portion 22.
  • the housing cylinder portion 22 is not limited to a cylindrical shape, and may be an elliptic cylinder shape, a polygonal cylinder shape, a deformed cylinder shape, or the like.
  • the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 are not limited to the cylindrical shape, and may be an elliptic cylinder shape, a polygonal cylinder shape, a deformed cylinder shape, or the like.
  • the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 may be provided separately from the housing body 16.
  • heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 may be provided in mutually interchanged positions. Further, the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 may be provided by being formed separately from the housing tubular portion 22 and attached to the peripheral wall portion of the housing tubular portion 22.
  • the bottom member 18 has a substantially disk shape or a bottomed cylindrical shape, and the outer peripheral portion is liquid-tightly fixed to the lower end portion of the housing body 16 over the entire circumference.
  • the protrusion projecting from the bottom member 18 toward the housing tubular portion 22 of the housing body 16 is fitted and fixed to the recess opening in the lower end surface of the housing tubular portion 22.
  • the bottom member 18 is provided with a circulating liquid inlet port 30.
  • the circulating liquid inlet port 30 has a substantially cylindrical shape and extends forward (leftward in FIG. 7) from the bottom member 18, and when the bottom member 18 is attached to the housing body 16, the circulating liquid inlet port 30 is provided.
  • the inner cavity of 30 communicates with the inner cavity of the housing cylinder portion 22 of the housing body 16.
  • the bottom member 18 is provided with a drug solution administration port 32.
  • the drug solution administration port 32 extends obliquely downward from the bottom wall portion of the bottom member 18 while inclining forward, and when the bottom member 18 is attached to the housing body 16, the inner cavity of the drug solution administration port 32. Is communicated with the inner cavity of the housing cylinder portion 22 of the housing body 16. Note that in FIG. 7, the drug solution administration port 32 is closed by a removable cap 34.
  • the bottom member 18 includes a groove portion 36 that extends radially from the opening of the circulating fluid inlet port 30.
  • the groove portion 36 is open to the upper surface of the bottom wall portion of the bottom member 18, and bottom upper portions 38 located above the bottom surface of the groove portion 36 are provided on both sides in the width direction of the groove portion 36, respectively.
  • the depth dimension from the upper end of the peripheral wall of the bottom member 18 is larger in the groove portion 36 than in the bottom upper portions 38, 38 which are out of the groove portion 36.
  • the position of the bottom surface of the groove portion 36 in the vertical direction is substantially constant in the length direction.
  • the upper surface of the bottom upper portion 38 is inclined downward as it goes away from the circulating liquid inlet port 30. Therefore, the depth of the groove 36 from the bottom upper portion 38 becomes smaller as the distance from the circulating liquid inlet port 30 increases.
  • the circulating fluid inlet port 30 is opened at one end of the groove 36, and the flow dividing projection 40 is provided at the other end of the groove 36.
  • the flow dividing projection 40 projects in the longitudinal direction of the groove 36 toward the circulating liquid inlet port 30 at a portion of the peripheral wall portion of the bottom member 18 facing the opening of the circulating liquid inlet port 30.
  • the width dimension of the flow dividing projection 40 in the circumferential direction of the bottom member 18 gradually decreases toward the tip.
  • the tip end portion has a convex curved shape toward the outside (projecting tip end side), and the base end portion has a concave curved shape toward the outside (both circumferential directions).
  • the lower end of the flow dividing projection 40 is continuous with the bottom surface of the groove portion 36 of the bottom member 18, and the upper end of the flow dividing projection 40 reaches the upper side of the bottom upper portions 38, 38.
  • Guide ridges 42 are provided on the upper portions 38, 38 of the bottom, respectively.
  • the guide ridges 42 are ridges that project upward from the upper surface of the bottom upper portion 38, respectively, and extend in predetermined directions in the circumferential direction of the bottom member 18 from both sides of the flow dividing projection 40 toward the circulating liquid inlet port 30 side. It extends in length.
  • One end of the guide ridge 42 in the circumferential direction is located apart from the flow dividing projection 40 in the circumferential direction, and the other end of the guide ridge 42 in the circumferential direction is an opening of the circulating fluid inlet port 30. It is located in the circumferential direction with respect to.
  • the guide ridges 42 are provided so as to face the inner surface of the peripheral wall of the bottom member 18 while being spaced apart from each other on the inner peripheral side. Since the upper surface of the bottom upper part 38 is inclined downward toward the diversion projection 40 side, and the upper end of the guide protrusion 42 extends substantially perpendicular to the vertical direction, The projecting height dimension gradually decreases from the flow dividing projection 40 side toward the circulating liquid inlet port 30 side. The circulating liquid flows into the bottom member 18 from the circulating liquid inlet port 30, collides with the flow dividing projection 40, then flows along the guide protrusion 42, and is guided to the circulating liquid inlet port 30 side.
  • the upper surface of the guide ridge 42 is located at substantially the same height as the upper surface of the flow dividing projection 40 in the vertical direction.
  • the lid member 20 has a bottomed cylindrical shape that is turned upside down as a whole, and in this embodiment, is divided into upper and lower wall portions and a peripheral wall portion that are fixed to each other. It is composed of two members. That is, the lid member 20 of the present embodiment includes the first liquid chamber wall member 44 fixed to the upper end portion of the housing body 16 and the second liquid chamber wall member fixed to the first liquid chamber wall member 44. And 46.
  • the lower end of the first liquid chamber wall member 44 is fixed to the upper end of the housing body 16 by means such as welding, and the first liquid chamber wall member 44 opens obliquely upward at the front (left in FIG. 11).
  • An inclined opening 48 is provided.
  • the periphery of the inclined opening portion 48 is a flat surface that is inclined rearward toward the upper side.
  • the upper wall portion of the first liquid chamber wall member 44 is provided with a substantially cylindrical degassing port 50, and the lower opening 52 of the degassing port 50 has a first liquid chamber wall member. It is formed on the inner wall surface of the upper side of 44, and the inner cavity of the degassing port 50 communicates with the internal space of the first liquid chamber wall member 44 (pre-degassing liquid chamber 80 described later).
  • the peripheral portion of the opening 52 of the degassing port 50 may include a tapered portion such as a curved surface shape or an inclined flat surface shape that gradually expands downward.
  • the guide of bubbles to the degassing port 50 described later is efficiently realized not only by the filter 78 described below, but also by the tapered shape of the opening peripheral edge portion of the degassing port 50.
  • the tapered surface may be provided up to a position continuous with the filter 78 described later, or the filter may be provided through a plane substantially orthogonal to the vertical direction.
  • a tapered surface may be provided at a position away from 78.
  • the degassing port 50 is closed by a removable cap 54.
  • a substantially cylindrical pressure detection port 56 is provided on the peripheral wall portion of the first liquid chamber wall member 44, and the inner cavity of the pressure detection port 56 is the first liquid.
  • a male screw is provided on the outer peripheral surface of the pressure detection port 56 while communicating with the internal space of the chamber wall member 44.
  • the pressure detection port 56 may be attached with a cap having a female screw corresponding to the male screw on the outer peripheral surface of the pressure detection port 56.
  • the lid member 20 it is preferable that at least the base end portion (root portion) of the degassing port 50 is made transparent so that the internal space can be visually confirmed from the outside. .
  • the entire housing 12 is transparent, but the housing body 16, the bottom member 18, and the lid member 20 may be opaque.
  • the lid member 20 may be subjected to embossing.
  • the first liquid chamber wall member 44 may be made transparent, and the second liquid chamber wall member 46 may be made opaque.
  • the second liquid chamber wall member 46 includes a circulating fluid outlet port 58 having a substantially cylindrical shape that extends forward, and the inner cavity of the circulating fluid outlet port 58 is the second. It communicates with the internal space of the liquid chamber wall member 46. Furthermore, the temperature detecting port 60 is provided in the second liquid chamber wall member 46, and the temperature detecting member 62 is provided in the temperature detecting port 60 in an inserted state. In the temperature detecting member 62, a tubular base 64 is fixed to the second liquid chamber wall member 46 at the temperature detecting port 60, and a test tube-shaped tip 66 is passed through the temperature detecting port 60 and the degassed liquid to be described later. It is inserted into the chamber 82, and the temperature of the circulating liquid in the liquid chamber 82 after deaeration can be measured.
  • the second liquid chamber wall member 46 is provided so as to close the inclined opening portion 48 of the first liquid chamber wall member 44, and the second liquid chamber wall member 46 serves as the first liquid chamber wall member 44.
  • the lid member 20 is formed by being liquid-tightly fixed.
  • the projection provided on the inclined opening portion 48 of the first liquid chamber wall member 44 is fitted and fixed to the concave portion provided on the second liquid chamber wall member 46.
  • the lower end portion of the lid member 20, which is constituted by the first liquid chamber wall member 44, is liquid-tightly fixed to the upper end portion of the housing body 16.
  • the projection provided on the lower end of the first liquid chamber wall member 44 is fitted and fixed to the recess opening on the upper end surface of the housing body 16.
  • the bottom member 18 is attached so as to cover the lower side of the housing cylindrical portion 22 in the housing body 16, and the lid member 20 is attached so as to cover the upper side of the housing cylindrical portion 22.
  • the hollow housing 12 is composed of a housing body 16, a bottom member 18, and a lid member 20.
  • the temperature detection port 60 and the pressure detection port 56 are all in communication with the internal space of the housing 12.
  • the heat exchange section 14 is housed in the internal space of the housing 12 having such a structure.
  • the heat exchange section 14 includes a plurality of heat transfer tubes 68, as shown in FIGS.
  • the heat transfer tube 68 has an elongated small-diameter cylindrical shape, and is preferably formed of a material having excellent corrosion resistance to a circulating fluid and a heat exchange medium described later and having a large thermal conductivity.
  • a material having excellent corrosion resistance to a circulating fluid and a heat exchange medium described later having a large thermal conductivity.
  • copper or aluminum It is formed of iron (stainless steel) or an alloy thereof.
  • the heat transfer tube 68 of the present embodiment extends linearly in the vertical direction, it is possible to prevent air from remaining in the lumen of the heat transfer tube 68 and to disturb the circulating fluid flowing through the lumen of the heat transfer tube 68. The flow is being reduced.
  • the heat transfer tube 68 is not limited to a linear tubular shape, and can be appropriately curved, for example, to obtain a large contact area with a heat exchange medium described later to improve the efficiency of heat exchange. ..
  • the cross-sectional shape, number, arrangement, etc. of the heat transfer tubes 68 are not limited to any one, and may be, for example, an elliptic cylinder shape, a polygonal cylinder shape, or a deformed cylinder shape.
  • fins may be provided on the outer peripheral surface of the heat transfer tube 68 to improve the efficiency of heat exchange.
  • the heat transfer tubes 68 are arranged as a tube group in which a plurality of heat transfer tubes 68 are bundled in a substantially columnar shape, and the lower end portions of the plurality of heat transfer tubes 68 are positioned relative to each other by a lower support plate 70 formed of urethane or the like.
  • the upper end portions are mutually positioned by the upper support plate 72 formed of urethane or the like.
  • Each of the lower support plate 70 and the upper support plate 72 is a substantially disc-shaped member formed of a synthetic resin or the like, and liquid-tightly closes the space between the plurality of heat transfer pipes 68 in the tube group. It projects to the outer periphery of the group and is fixed to the housing body 16.
  • the support plates 70 and 72 may be formed into a shape having an insertion hole for the heat transfer tube 68, and then the heat transfer tube 68 may be inserted into the insertion hole and adhered thereto. While being set on the inner circumference of the housing 22, the inner circumference of both axial ends of the housing cylinder 22 is filled with a potting resin to be molded, so that the heat transfer tube 68 and the housing cylinder 22 are fixedly formed. You can also
  • the lower support plate 70 is fixed to the lower end portion of the housing tubular portion 22, and the upper support plate 72 is fixed to the upper end portion of the housing tubular portion 22, so that the plurality of heat transfer tubes 68 are arranged in the housing tubular portion 22. It is supported so as to extend vertically in the inner circumference.
  • the heat transfer tube 68 has a lower opening communicating with the circulating liquid inlet port 30 and the chemical liquid administration port 32 through the internal space of the bottom member 18, and an upper opening through the internal space of the lid member 20. And the deaeration port 50.
  • the inner peripheral surface of the housing tubular portion 22 of the housing body 16 gradually contracts upward, and in the present embodiment, has a tapered shape with a gradually decreasing diameter. Thereby, the distance between the facing surfaces of the inner peripheral surface of the housing tubular portion 22 and the outer peripheral surface of the tube group including the plurality of heat transfer tubes 68 becomes smaller as it goes upward.
  • the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 are communicated with each other through the plurality of heat transfer tubes 68, and the space between the heat transfer tubes 68 has a bottom member 18 and a lid member 20.
  • the inner spaces are liquid-tightly separated by the support plates 70 and 72.
  • the pre-temperature-controlling liquid chamber 74 is configured by the internal space of the bottom member 18, the circulating liquid inlet port 30 and the chemical liquid administration port 32 are communicated with each other, and the lower ends of the inner cavities of the plurality of heat transfer tubes 68 are communicated with each other. Has been done.
  • the temperature-adjusted liquid chamber 76 is constituted by the internal space of the lid member 20, and the deaeration port 50, the pressure detection port 56, the circulating liquid outlet port 58, and the temperature detection port 60 are connected to each other, and a plurality of them are provided.
  • the lumens of the heat transfer tube 68 communicate with each other.
  • the temperature detecting member 62 inserted into the temperature detecting port 60 has a tip portion 66 protruding into the liquid chamber 76 after temperature adjustment.
  • a filter 78 is arranged in the temperature-adjusted liquid chamber 76.
  • the filter 78 is a polymer film that allows passage of the circulating liquid and restricts the passage of air.
  • the filter 78 has a flat membrane shape and is tilted up and down in the liquid chamber 76 after temperature adjustment. It is arranged in a stretched state so as to spread. More specifically, as shown in FIG. 11, the filter 78 is provided so as to close the inclined opening portion 48 of the first liquid chamber wall member 44, and the opening of the degassing port 50 from the bottom to the top. It is inclined and spreads backward (to the right in FIG. 11) so as to approach 52.
  • the filter 78 is fixedly supported by the wall portion that defines the temperature-adjusted liquid chamber 76 at the entire peripheral edge thereof, and particularly, the lower end portion is supported by the lower portion of the cylindrical peripheral wall of the temperature-adjusted liquid chamber 76. In addition to being supported, the upper end portion is supported by the wall portion of the upper bottom of the liquid chamber 76 after temperature adjustment. Note that, in FIGS. 7 and 11, the thickness of the filter 78 is illustrated thicker than it actually is for the sake of easy viewing.
  • the filter 78 of the present embodiment is set in the mold of the first liquid chamber wall member 44 in advance and insert-molded when the first liquid chamber wall member 44 is molded. It is an insert constituent member that constitutes the insert molded article.
  • the filter 78 is fixedly attached to the first liquid chamber wall member 44 in a state where the peripheral edge of the filter 78 is welded or inserted inside, and is integrally attached.
  • the outer peripheral edge of the filter 78 is directly fixed to the opening peripheral edge portion of the inclined opening portion 48 of the first liquid chamber wall member 44 constituting the housing 12 over the entire circumference.
  • the material for forming the filter 78 is not particularly limited, but is preferably formed of a hydrophobic polymer material such as polyester, polyamide, polyolefin, or fluororesin.
  • a hydrophobic polymer material such as polyester, polyamide, polyolefin, or fluororesin.
  • the filter 78 may be made of a hydrophilic polymer material, and if the filter 78 is made of a hydrophilic material, the circulating liquid can easily pass through the filter 78.
  • the filter 78 can also appropriately have both hydrophilicity and hydrophobicity depending on the required performance.
  • the temperature-adjusted liquid chamber 76 is divided into two parts on both sides of the filter 78 by disposing the filter 78 in the temperature-adjusted liquid chamber 76. That is, in the rear of the filter 78, the pre-degassing liquid chamber 80 in which the plurality of heat transfer pipes 68, the degassing port 50, and the pressure detection port 56 communicate with each other is formed, while in front of the filter 78, the circulation is performed.
  • a post-degassing liquid chamber 82 is formed in which the liquid outlet port 58 and the temperature detection port 60 communicate with each other.
  • the wall portion of the pre-degassing liquid chamber 80 and the degassing port 50 are integrally formed in the first liquid chamber wall member 44, and the wall portion of the post-degassing liquid chamber 82.
  • the circulating liquid outlet port 58 is integrally formed in the second liquid chamber wall member 46.
  • the pressure in the pre-degassing liquid chamber 80 can be measured by a pressure sensor (not shown) by the pressure detection port 56, and the temperature in the post-degassing liquid chamber 82 can be measured by the temperature detection port 60 including the temperature detection member 62. Can be measured.
  • the circulating fluid inlet port 30 and the circulating fluid outlet port 58 are connected to an extracorporeal circulation circuit (not shown), and the heat exchange medium inlet port 24 and the heat exchange medium outlet are provided. It is used with the port 26 connected to a heat exchange medium circulation circuit (not shown).
  • the extracorporeal circulation circuit aims to supply oxygen and prevent myocardial damage by circulating blood and administering cardioplegic solution to patients in cardiac arrest.
  • the extracorporeal circulation circuit of the present embodiment includes a circuit incorporating an artificial lung for temporarily replacing the functions of the heart and lungs, a heat exchanger, a blood pump, and a circuit for injecting a cardioplegic solution into the heart.
  • a crystalline cardioplegic solution, blood, a blood-added cardioplegic solution in which blood is mixed with a crystalline cardioplegic solution, and the like are preferably used.
  • the composition of the crystalline cardioplegic solution is not particularly limited, it is generally a high potassium solution and carries oxygen required for cardioplegia.
  • the heat exchanger 10 for the myocardial protection circuit is exemplified, but the heat exchanger according to the present invention is not necessarily used only for the myocardial protection circuit, and for example, a patient is placed in a hypothermic state. It can also be applied to a heat exchanger for an artificial heart-lung circuit used when performing heat treatment.
  • the heat exchange medium circulation circuit includes a pump for circulating the heat exchange medium and a temperature control device for cooling or heating the heat exchange medium.
  • the heat exchange medium may be any fluid that can flow through the heat exchange medium circulation circuit, but a liquid such as water is preferably used.
  • a priming process is performed. That is, by filling the circulating fluid inlet port 30 to the circulating fluid outlet port 58 with the circulating fluid, the circulating fluid inlet port 30, the medicinal solution administration port 32, the pre-temperature regulating liquid chamber 74, and the plurality of circulating fluid inlet ports 30 located on the circulating path of the circulating fluid are provided.
  • the heat transfer pipe 68, the temperature-adjusted liquid chamber 76, the circulating liquid outlet port 58, the degassing port 50, and the pressure detection port 56 are filled with the circulating liquid to discharge the air.
  • the air flows from the degassing port 50 to the outside until the pre-degassing liquid chamber 80 is filled with the circulating liquid. Is discharged. Further, the air mixed in the circulating fluid filling the pre-degassing liquid chamber 80 is filtered out by the filter 78, becomes air bubbles and floats up along the filter 78, so that the air above the pre-degassing liquid chamber 80 is removed. It is discharged to the outside from the deaeration port 50 provided on the wall.
  • the air in the post-degassing liquid chamber 82 is discharged from the circulating liquid outlet port 58 to an extracorporeal circulation circuit (not shown), and is provided in the extracorporeal circulation circuit.
  • the air trap is discharged to the outside of the circulation circuit. 7 and 11, the cap 54 is attached to the deaeration port 50, but the cap 54 is removed when performing the priming process, and a tube or the like (not shown) is connected to the deaeration port 50.
  • the priming process is performed in.
  • the pressure detection port 56 is liquid-tightly sealed when a pressure sensor (not shown) is inserted or when the pressure sensor is not inserted.
  • the filter 78 is inclined toward the degassing port 50, and more specifically, is provided so as to be inclined upward so as to approach the opening 52 of the degassing port 50, The bubbles floating along the filter 78 are guided to the degassing port 50, and the air is efficiently discharged from the degassing port 50 to the outside. Therefore, it is difficult for the air to remain in the pre-degassing liquid chamber 80 after the priming process, and the removal of the air in the circulating liquid can be effectively realized.
  • the circulating liquid in the pre-degassing liquid chamber 80 which may contain bubbles, comes into contact with the lower surface of the obliquely arranged filter 78, the bubbles removed from the circulating liquid by the filter 78 are buoyant. Thus, it floats along the filter 78. Therefore, it is possible to stably guide the bubbles to the degassing port 50.
  • the filter 78 since the filter 78 has a flat shape, the bubbles are efficiently guided in the direction parallel to the surface of the filter 78 and guided to the degassing port 50. Moreover, since the filter 78 is arranged obliquely, it is possible to secure a large area of the filter 78 even if the filter 78 has a flat shape, and it is possible to obtain a large flow rate of the circulating liquid passing through the filter 78. You can
  • the filter 78 is directly fixed to the first liquid chamber wall member 44 of the housing 12 by insert molding, the filter 78 is indirectly attached to the first liquid chamber wall member 44 via another member. Compared with the case, it is more difficult to form a step or unevenness in the mounting portion of the filter 78 on the inner surface of the wall of the first liquid chamber wall member 44. Therefore, it is difficult for the air to remain after the completion of the priming process, and the efficient discharge of the air is realized. In addition, steps or irregularities are unlikely to be formed in the mounting portion of the filter 78 on the inner wall surface of the second liquid chamber wall member 46, and air is prevented from remaining after the priming process is completed.
  • the flow of the circulating liquid flowing from the circulating liquid inlet port 30 to the inside of the bottom member 18 is smoothly guided to both sides in the circumferential direction without being blocked by the peripheral wall of the bottom member 18 which is substantially orthogonal to the flow. .. Therefore, entrainment of bubbles due to turbulent flow is unlikely to occur, and the inside of the bottom member 18 can be quickly filled with the circulating liquid.
  • guide ridges 42, 42 extending in the circumferential direction from the flow dividing projection 40 toward the circulating liquid inlet port 30 are provided on both sides in the circumferential direction of the bottom member 18 with respect to the flow dividing projection 40.
  • the flow of the circulating liquid divided into both sides in the circumferential direction by the flow dividing projection 40 is guided in the circumferential direction on the outer peripheral portion of the bottom member 18 by the guide projections 42, 42.
  • the flow of the circulating liquid whose direction has been changed by the flow dividing projections 40 hardly collides with the flow of the circulating liquid flowing from the circulating liquid inlet port 30 and passing through the center of the bottom member 18, and thus the flow collides. Turbulent flow due to
  • the circulating fluid inlet port 30 is open at the end surface of the groove 36, and is located below the upper surfaces of the bottom upper portions 38, 38. Therefore, the flow of the circulating liquid flowing in from the circulating liquid inlet port 30 and the flow of the circulating liquid flowing on the bottom upper portions 38, 38 guided by the guide protrusions 42, 42 are displaced from each other even in the vertical direction. They are formed and are hard to bump into each other.
  • the outer peripheral portions where the guide ridges 42, 42 are provided are the bottom upper portions 38, 38 having a shallower depth than the groove portion 36, the flow of the circulating liquid divided by the flow dividing protrusions 40 is applied to the heat transfer pipe 68. Flow near the end opening. Therefore, the circulating liquid introduced into the bottom member 18 is easily guided to the inner cavity of the heat transfer tube 68, and the circulating liquid can be efficiently introduced into the heat exchange section 14.
  • the bottom upper portion 38 gradually inclines from the side of the flow dividing projection 40 toward the side of the circulating liquid inlet port 30 and approaches the end opening of the heat transfer tube 68. Therefore, also on the circulating liquid inlet port 30 side, the circulating liquid flowing on the bottom upper portion 38 is effectively introduced into the inner cavity of the heat transfer tube 68.
  • the temperature of the circulating fluid is adjusted by the heat exchanger 10, and the temperature-controlled circulating fluid is supplied to the extracorporeal circulation circuit. That is, the heat exchange medium introduced into the heat exchange medium inlet port 24 is discharged from the heat exchange medium outlet port 26 through the gap provided between the plurality of heat transfer tubes 68.
  • the circulating liquid that has entered the heat exchanger 10 from the circulating liquid inlet port 30 is indirectly contacted with the heat exchange medium when passing through the inner cavity of the heat transfer pipe 68, and the heat transfer pipe is provided between the circulating liquid and the heat exchange medium. Heat exchange (transfer) via 68 occurs.
  • the temperature of the circulating liquid is adjusted, and the circulating liquid whose temperature has been adjusted in the heat exchange section 14 flows into the temperature-adjusted liquid chamber 76 (pre-degassing liquid chamber 80).
  • the temperature of the circulating liquid that has passed through the heat exchanger 10 is not particularly limited, but it is desirable that it be compatible with both cooling and heating. For example, by cooling the circulating fluid used in the cardiac arrest state, the myocardium is protected under cardiac arrest, and at the time of releasing cardiac arrest, the circulating fluid heated to the living body temperature is supplied to the patient, Can restore the normal metabolic function of the heart. When both cooling and heating are possible, the circulating liquid during cooling and the circulating liquid during heating may be the same as each other or may be different from each other.
  • the heat exchange medium is introduced into the space on the inner peripheral side of the housing tubular portion 22 from the lower portion and discharged from the lower portion, so that the heat exchange medium does not easily flow to the upper portion of the housing tubular portion 22. Therefore, the inner peripheral surface of the accommodating cylinder portion 22 is formed into a taper shape having a smaller diameter toward the upper side, and the opposing surface between the inner peripheral surface of the accommodating cylinder portion 22 and the outer peripheral surface of the tube group including the plurality of heat transfer tubes 68. The distance is gradually decreasing upward. As a result, the heat exchange medium fed from the lower portion of the accommodating cylinder portion 22 is suppressed from decreasing in the flow velocity due to pressure loss, and easily flows to the upper portion of the accommodating cylinder portion 22. Therefore, the heat exchange medium flowing in from the heat exchange medium inlet port 24 is supplied to the entire heat exchange section 14, and the heat exchange efficiency between the circulating liquid and the heat exchange medium is improved.
  • the circulating liquid introduced from the circulating liquid inlet port 30 to the heat exchange section 14 flows through the lumen of the heat transfer tube 68, and the heat exchange medium flows between the outer peripheral surfaces of the plurality of heat transfer tubes 68.
  • the volume of the circulation region of the circulating liquid (the inner cavity of the heat transfer pipe 68) is made smaller than the volume of the flow region of the heat exchange medium (the gap between the plurality of heat transfer pipes 68). Therefore, the amount of the priming liquid remaining in the heat exchange unit 14 at the time of completion of the priming is reduced, and it is possible to suppress the dilution of blood by the priming liquid entering the body (blood vessel) of the patient from the extracorporeal circulation circuit.
  • the drug solution can be appropriately administered from the drug solution administration port 32 to the circulating fluid.
  • the cap 34 is attached to the drug solution administration port 32, but the cap 34 may be removed at the time of drug solution administration, or the cap may be previously removed and a tube (not shown) may be connected, and the tube may be removed.
  • the drug solution administration port 32 may be blocked by clamping.
  • the air mixed in the circulating fluid is removed by the filter 78 and collected in the degassing port 50 even in the use state after the priming of the heat exchanger 10 is completed.
  • the deaeration port 50 is shut off after the priming is completed, and leakage of the circulating fluid from the deaeration port 50 is prevented.
  • the state where the air is collected in the deaeration port 50 includes the deaeration port 50. Since the first liquid chamber wall member 44 is transparent, it can be visually confirmed from the outside. Therefore, when it is confirmed that the air has collected in the deaeration port 50, the air can be discharged to the outside by temporarily opening the deaeration port 50. Since the deaeration port 50 is blocked by clamping the tube connected to the deaeration port 50 after the completion of the priming process, when the air is exhausted while the heat exchanger 10 is in use, You can temporarily release the clamp.
  • the temperature detection port 60 is provided on the wall portion of the post-degassing liquid chamber 82 filled with the circulating liquid from which air has been removed by the filter 78, and the temperature detection member 62 is used to remove the post-degassing liquid from the temperature detection port 60. Even if the bubbles are provided so as to project into the chamber 82, the bubbles do not adhere to the temperature detecting member 62 and remain in the liquid chamber.
  • the flowing direction of the circulating liquid and the flowing direction of the heat exchanging medium in the heat exchanging section 14 are set to intersect with each other, but both the circulating liquid and the heat exchanging medium flow vertically.
  • the flowing direction of the circulating liquid may be the same as the flowing direction of the heat exchange medium, or may be the opposite direction.
  • the filter 78 is not limited to a flat shape, and may be, for example, a tapered cylindrical shape whose diameter decreases upward.
  • the upper end of the filter 78 is arranged so as to surround the opening 52 of the degassing port 50, so that bubbles moving upward along the filter 78 are guided to the degassing port 50.
  • the filter 78 may have a curved plate shape, a corrugated plate shape, a bent plate shape, or the like.
  • the method of fixing the filter 78 to the housing body 16 is not limited to insert molding. Specifically, a method of adhering the filter 78 to the housing body 16 as a separate component from the housing body 16 can be mentioned.
  • the entire housing 12 does not need to be transparent, and for example, only the lid member 20 forming the upper wall portion of the housing 12 may be transparent, or the degassing provided on the lid member 20 may be performed. Only the port 50 may be transparent. In order to confirm the presence or absence of air bubbles from the outside, it is desirable that at least the root portion of the degassing port 50 is transparent or translucent, and more preferably, the degassing port 50 and the pre-degassing liquid chamber 80. Although the first liquid chamber wall member 44 forming the wall portion is transparent or translucent, the entire housing 12 can be formed of an opaque material.
  • the heat exchanger 10 may introduce the patient's blood into the circulating fluid passage in order to reduce the physical burden on the patient.
  • the housing 12 may be provided with a service port connected to an external conduit for introducing blood into the flow path of the circulating fluid.
  • the service port is provided at a position where blood can be mixed into the circulating fluid before passing through the filter 78, considering that air is mixed due to the connection with the external pipeline.
  • the service port can be provided in the first liquid chamber wall member 44 of the bottom member 18 or the lid member 20, and for example, the pressure detection port 56 of the above-described embodiment can be used as the service port. it can.
  • the blood reservoir that stores the blood introduced into the flow path of the circulating fluid can be attached to the outer peripheral surface of the housing cylinder portion 22 by the attachment protrusions 28 a and 28 b provided on the housing 12, for example.

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Abstract

Provided is a heat exchanger that has a novel structure and is capable of effectively removing bubbles in a circulating-fluid. This heat exchanger (10) is provided with a heat exchanging unit (14) that adjusts the temperature of a circulating-fluid, the heat exchanger (10) having a temperature-adjusted fluid chamber (76) into which flows the circulating-fluid, the temperature of which has been adjusted in the heat exchanging unit (14), the temperature-adjusted fluid chamber (76) having a filter (78) disposed for removing air in the circulating-fluid and having a deaeration port (50) formed on a wall portion thereof, and the filter (78) being angled toward an opening (52) of the deaeration port (50).

Description

熱交換器Heat exchanger
 本発明は、心停止下での手術において、心筋保護液や血液などの循環液の温度を調節するために用いられる医療用の熱交換器に関するものである。 The present invention relates to a medical heat exchanger used for controlling the temperature of circulating fluid such as myocardial protection fluid and blood during surgery under cardiac arrest.
 従来から、心臓や大血管の手術などを行う際には、心臓の拍動を停止することで、手技の容易化を図る手法が採用されている。このような心停止法による手術では、心臓を停止させるためにカリウム溶液などの薬液が投与されるが、薬液による心臓の停止は、心筋に損傷を与える場合もあることから、心筋を保護するために心筋を冷却することも、従来から行われている。 ❖ Conventionally, when performing surgery on the heart or large blood vessels, a technique has been adopted that facilitates the procedure by stopping the pulsation of the heart. In such an operation using the cardiac arrest method, a drug solution such as a potassium solution is administered to stop the heart. However, since stopping the heart with the drug solution may damage the myocardium, it is necessary to protect the myocardium. Cooling the myocardium is also a traditional practice.
 ところで、心筋を冷却する手段としては、例えば、血液や薬液(例えば心筋保護液)などの循環液を低温にして心臓の冠状動脈に送り込むことで心筋を冷却することが、一般的に行われている。 By the way, as a means for cooling the myocardium, for example, it is generally performed to cool the myocardium by lowering the temperature of circulating fluid such as blood or drug solution (for example, cardioplegic solution) and sending it to the coronary arteries of the heart. There is.
 この場合には、心臓の冠状動脈などに接続される熱交換器によって、循環液の温度調節(冷却)が行われる。熱交換器は、例えば、特許第3742711号公報(特許文献1)に記載された医療用熱交換器(1)のように、循環液と熱交換媒体の間での熱交換によって循環液の温度を調節する熱交換体(3)を備えていると共に、温度調節された循環液が流入する生体循環用液体流通室(13)には、気泡捕捉用フィルター部材(16)が設けられている。そして、気泡捕捉用フィルター部材を通過した循環液が患者の体内管腔(血管)へ送り込まれることにより、心筋が循環液によって冷却されるようになっている。 In this case, the temperature of the circulating fluid is controlled (cooled) by a heat exchanger connected to the coronary arteries of the heart. The heat exchanger is, for example, like the medical heat exchanger (1) described in Japanese Patent No. 3742711 (Patent Document 1), the temperature of the circulating liquid by heat exchange between the circulating liquid and the heat exchange medium. In addition to the heat exchanger (3) for adjusting the temperature, a bubble-trapping filter member (16) is provided in the biological circulation liquid circulation chamber (13) into which the temperature-controlled circulating liquid flows. Then, the circulating fluid that has passed through the bubble trapping filter member is fed into the body lumen (blood vessel) of the patient, whereby the myocardium is cooled by the circulating fluid.
 しかしながら、特許文献1の医療用熱交換器では、生体循環用液体流通室内の空気が気泡除去口(41)から外部へ十分に排出されずに残留するおそれがあった。すなわち、気泡捕捉用フィルター部材によって生体循環用液体流通室に留められた気泡は、浮力によって上方へ移動しても、気泡除去口(41)へ導かれずに、圧力モニタリングポート(44)や温度モニタリングポート(45)、ポート(57)などに引っ掛かって残留する場合がある。また、特許文献1において、気泡捕捉用フィルター部材は、液体流通室形成部材(17)に取り付けられた状態で、液体流通室形成部材がハウジング(2)に取り付けられることで、所定の位置に設けられるようになっているが、このような他部材(液体流通室形成部材)を介したフィルターの取付構造では、他部材とハウジングの間に段差などが形成され易く、当該段差などに気泡が残り易かった。 However, in the medical heat exchanger of Patent Document 1, there is a possibility that the air in the liquid circulation chamber for biological circulation may remain outside without being sufficiently discharged from the bubble removal port (41). That is, the bubbles retained in the biological circulation liquid circulation chamber by the bubble capturing filter member are not guided to the bubble removal port (41) even if moved upward by buoyancy, and the pressure monitoring port (44) and temperature monitoring are performed. There is a case where the port (45) or the port (57) is caught and remains. Further, in Patent Document 1, the bubble capturing filter member is provided at a predetermined position by being attached to the housing (2) while being attached to the liquid circulation chamber forming member (17). However, in the mounting structure of the filter through such another member (liquid circulation chamber forming member), a step or the like is easily formed between the other member and the housing, and bubbles remain in the step or the like. It was easy.
特許第3742711号公報Japanese Patent No. 3742711
 本発明は、上述の事情を背景に為されたものであって、その解決課題は、循環液中の気泡を効率的に除去することができる、新規な構造の熱交換器を提供することにある。 The present invention has been made in view of the above circumstances, and a problem to be solved is to provide a heat exchanger having a novel structure capable of efficiently removing bubbles in a circulating liquid. is there.
 以下、このような課題を解決するために為された本発明の態様を記載する。なお、以下に記載の各態様において採用される構成要素は、可能な限り任意の組み合わせで採用可能である。 The following describes aspects of the present invention made to solve such problems. The constituent elements used in each of the following aspects can be used in any combination as much as possible.
 すなわち、本発明の第1の態様は、循環液の温度を調節する熱交換部を備えた熱交換器であって、前記熱交換部において温度調節された前記循環液が流入する調温後液室が設けられていると共に、該調温後液室には該循環液中の空気を除去するフィルタが配されて、該調温後液室の壁部には脱気ポートが設けられており、該フィルタが該脱気ポートへ向けて傾斜して設けられていることを、特徴とする。 That is, the first aspect of the present invention is a heat exchanger including a heat exchange unit that adjusts the temperature of the circulating liquid, wherein the temperature-adjusted liquid into which the circulating liquid whose temperature has been adjusted in the heat exchange unit flows. A chamber is provided, a filter for removing air in the circulating liquid is arranged in the temperature-adjusted liquid chamber, and a deaeration port is provided on the wall of the temperature-adjusted liquid chamber. The filter is provided so as to be inclined toward the deaeration port.
 本態様に従う構造とされた熱交換器によれば、循環液の通過を許容し且つ循環液に混ざった空気の通過を制限するフィルタが、脱気ポートの開口へ向けて傾斜していることから、フィルタによって濾しとられた空気が、フィルタに沿って浮上することで脱気ポートへ案内される。これにより、空気が調温後液室に残留することなく脱気ポートから外部へ排出され易くなって、循環液に混ざった空気を効率的に除去することができる。 According to the heat exchanger having the structure according to the present aspect, the filter that allows the passage of the circulating liquid and restricts the passage of the air mixed with the circulating liquid is inclined toward the opening of the degassing port. The air filtered by the filter is guided to the deaeration port by floating along the filter. As a result, the air does not remain in the liquid chamber after temperature adjustment and is easily discharged to the outside from the degassing port, and the air mixed with the circulating liquid can be efficiently removed.
 本発明の第2の態様は、第1の態様に記載された熱交換器において、前記調温後液室は前記フィルタの両側が脱気前液室と脱気後液室とされており、前記脱気ポートが該脱気前液室の壁部に設けられているものである。 A second aspect of the present invention is the heat exchanger according to the first aspect, wherein the temperature-adjusted liquid chamber has a pre-degassing liquid chamber and a post-degassing liquid chamber on both sides of the filter. The degassing port is provided on the wall of the pre-degassing liquid chamber.
 本態様に従う構造とされた熱交換器によれば、脱気ポートが脱気前液室の壁部に設けられていることにより、脱気ポートが脱気後液室に設けられている場合に比して、体内への気泡の混入を防止し、循環液に混ざった空気を効率的に除去することができる。 According to the heat exchanger having the structure according to the present aspect, since the degassing port is provided in the wall portion of the pre-degassing liquid chamber, the degassing port is provided in the post-degassing liquid chamber. In comparison, it is possible to prevent air bubbles from entering the body and efficiently remove the air mixed with the circulating fluid.
 本発明の第3の態様は、第1又は第2の態様に記載された熱交換器において、前記フィルタが、前記調温後液室の壁部を構成するハウジングにインサート成形されたインサート構成部材とされているものである。 A third aspect of the present invention is the heat exchanger according to the first or second aspect, in which the filter is insert-molded into a housing forming a wall of the temperature-adjusted liquid chamber. It is said that.
 本態様に従う構造とされた熱交換器によれば、フィルタをハウジングに対してインサート成形で直接的に取り付けることで、フィルタをハウジングに固定するための別部材が不要になって、部品点数の削減や構造の簡略化が図られる。 According to the heat exchanger having the structure according to this aspect, the filter is directly attached to the housing by insert molding, so that a separate member for fixing the filter to the housing is not required, and the number of parts is reduced. And the structure can be simplified.
 さらに、フィルタがハウジングに対して別部材を介して取り付けられている場合に比して、フィルタの取付部分に段差や凹凸などが形成され難く、調温後液室の壁部における段差や凹凸などを少なくすることができる。その結果、例えば、プライミング完了後に空気が調温後液室内に残留し難くなって、循環液に混ざった空気を効率的に除去することができる。 Further, as compared with the case where the filter is attached to the housing via another member, it is difficult to form steps or irregularities on the filter attachment portion, and steps and irregularities on the wall of the liquid chamber after temperature adjustment are not present. Can be reduced. As a result, for example, air is less likely to remain in the liquid chamber after temperature adjustment after the priming is completed, and the air mixed with the circulating liquid can be efficiently removed.
 本発明の第4の態様は、第1~第3の何れか1つの態様に記載された熱交換器において、前記調温後液室内の温度を測定するための温度検出ポートが、前記調温後液室の壁部に設けられているものである。 A fourth aspect of the present invention is the heat exchanger according to any one of the first to third aspects, wherein the temperature detection port for measuring the temperature in the liquid chamber after temperature adjustment is the temperature adjustment port. It is provided on the wall of the rear liquid chamber.
 本態様に従う構造とされた熱交換器によれば、例えば、温度検出ポート自体が調温後液室に突出している場合や、温度検出ポートに差し入れられる温度センサなどが調温後液室に突出する場合に、気泡が温度検出ポートや温度センサなどに引っ掛かって残留する問題が生じ難い。 According to the heat exchanger configured according to the present aspect, for example, when the temperature detection port itself projects into the liquid chamber after temperature adjustment, or a temperature sensor inserted into the temperature detection port projects into the liquid chamber after temperature adjustment. In this case, the problem that air bubbles are caught in the temperature detection port or the temperature sensor and remain will not easily occur.
 本発明の第5の態様は、第1~第4の何れか1つの態様に記載された熱交換器において、前記脱気ポートの少なくとも根元部分が透明とされているものである。 A fifth aspect of the present invention is the heat exchanger according to any one of the first to fourth aspects, wherein at least the root portion of the degassing port is transparent.
 本態様に従う構造とされた熱交換器によれば、脱気ポート内の様子を外部から視認することが可能であり、例えば、脱気ポートに空気が溜まっている状態を目視で確認した上で、脱気ポートの開閉弁を開くなどして空気を外部に排出することも可能になる。 According to the heat exchanger having the structure according to this aspect, it is possible to visually check the inside of the deaeration port from the outside, for example, after visually confirming the state where the air is accumulated in the deaeration port. It is also possible to discharge air to the outside by opening the opening / closing valve of the degassing port.
 本発明の第6の態様は、第1~第5の何れか1つの態様に記載された熱交換器において、前記フィルタが平坦な形状とされているものである。 A sixth aspect of the present invention is the heat exchanger according to any one of the first to fifth aspects, in which the filter has a flat shape.
 本態様に従う構造とされた熱交換器によれば、フィルタに気泡が引っ掛かることなく脱気ポートまで効率的に案内される。しかも、平坦な形状のフィルタであっても、傾斜して設けられることで十分なフィルタ面積を確保することが可能であり、空気を有効に除去しながら必要とされる循環液の流量を確保することができる。 According to the heat exchanger having the structure according to this aspect, bubbles are efficiently guided to the degassing port without being caught in the filter. Moreover, even if the filter has a flat shape, it is possible to secure a sufficient filter area by providing the filter in a slanted manner, and secure the required flow rate of the circulating liquid while effectively removing air. be able to.
 本発明の第7の態様は、第1~第6の何れか1つの態様に記載された熱交換器において、前記フィルタが疎水性材料で形成されているものである。 A seventh aspect of the present invention is the heat exchanger according to any one of the first to sixth aspects, in which the filter is made of a hydrophobic material.
 本態様に従う構造とされた熱交換器によれば、気泡がフィルタに沿って移動し易くなることで脱気ポートへ効率的に案内されることから、空気の排出効率の向上が図られる。 According to the heat exchanger having the structure according to this aspect, the bubbles are easily moved along the filter, so that the bubbles are efficiently guided to the degassing port, so that the air discharge efficiency is improved.
 本発明の第8の態様は、第1~第6の何れか1つの態様に記載された熱交換器において、前記フィルタが親水性材料で形成されているものである。 An eighth aspect of the present invention is the heat exchanger according to any one of the first to sixth aspects, in which the filter is made of a hydrophilic material.
 本態様に従う構造とされた熱交換器によれば、循環液がより容易にフィルタを通過することができる。 According to the heat exchanger configured according to this aspect, the circulating liquid can more easily pass through the filter.
 また、本発明の第9の態様は、循環液の温度を調節する熱交換部を備えた熱交換器であって、前記熱交換部において温度調節された前記循環液が流入する調温後液室が設けられていると共に、該調温後液室には該循環液中の空気を除去するフィルタが配されて、該調温後液室における該フィルタの両側が脱気前液室と脱気後液室とされていると共に、該フィルタが該調温後液室の壁部を構成するハウジングにインサート成形されたインサート構成部材とされていることを、特徴とする。 Further, a ninth aspect of the present invention is a heat exchanger including a heat exchange part for adjusting the temperature of the circulating liquid, wherein the temperature-adjusted liquid into which the circulating liquid whose temperature has been adjusted in the heat exchange part flows. A chamber is provided, and a filter for removing air in the circulating liquid is disposed in the post-temperature-controlling liquid chamber, and both sides of the filter in the post-temperature-controlling liquid chamber are separated from the pre-degassing liquid chamber. The filter is an after-effect liquid chamber, and the filter is an insert component member that is insert-molded into a housing that forms a wall portion of the temperature-adjusted liquid chamber.
 本態様に従う構造とされた熱交換器によれば、フィルタをハウジングに対してインサート成形で直接的に取り付けることで、フィルタをハウジングに固定するための別部材が不要になって、部品点数の削減や構造の簡略化が図られる。 According to the heat exchanger having the structure according to the present aspect, the filter is directly attached to the housing by insert molding, so that a separate member for fixing the filter to the housing is not required, and the number of parts is reduced. And the structure can be simplified.
 さらに、フィルタをハウジングに対して別部材を介して取り付ける場合に比して、フィルタの取付部分に段差や凹凸などが形成され難く、調温後液室の壁部における段差や凹凸などを少なくすることができる。その結果、例えば、プライミング完了後に空気が調温後液室内に残留し難くなって、循環液に混ざった空気を効率的に除去することができる。 Further, as compared with the case where the filter is attached to the housing through another member, it is difficult to form steps or irregularities on the mounting portion of the filter, and the steps and irregularities on the wall of the liquid chamber after temperature adjustment are reduced. be able to. As a result, for example, air is less likely to remain in the liquid chamber after temperature adjustment after the priming is completed, and the air mixed with the circulating liquid can be efficiently removed.
 本発明の第10の態様は、第9の態様に記載された熱交換器において、前記ハウジングが前記脱気前液室の壁部を構成する第1の液室壁部材と前記脱気後液室の壁部を構成する第2の液室壁部材とを備えており、前記フィルタが該ハウジングの該第1の液室壁部材に取り付けられているものである。 A tenth aspect of the present invention is the heat exchanger according to the ninth aspect, wherein the housing constitutes a wall portion of the pre-degassing liquid chamber and the post-degassing liquid. A second liquid chamber wall member constituting a wall portion of the chamber, and the filter is attached to the first liquid chamber wall member of the housing.
 本態様に従う構造とされた熱交換器によれば、第1の液室壁部材は、例えば、熱交換部などに接続される開口を設けることで、フィルタをインサート成形しても成形後に金型から取外し易く、フィルタを備えたハウジングの製造が容易になる。 According to the heat exchanger having the structure according to the present aspect, the first liquid chamber wall member is provided with an opening connected to, for example, a heat exchange section, so that even if the filter is insert-molded, the mold can be formed after the molding. It is easy to remove and the housing with the filter is easily manufactured.
 本発明の第11の態様は、第1~第10の何れか1つの態様に記載された熱交換器において、前記熱交換部に連通されて前記循環液を該熱交換部へ導入する循環液入口ポートを備えた底部材が設けられており、該底部材における該循環液入口ポートの開口と対向する部分には、該循環液入口ポートに向けて突出する分流突起が設けられていると共に、該分流突起に対する該底部材の周方向の両側には、該底部材の周方向に延びるガイド突条が設けられているものである。 An eleventh aspect of the present invention is the heat exchanger according to any one of the first to tenth aspects, wherein the circulating liquid is communicated with the heat exchange section and introduces the circulating liquid into the heat exchange section. A bottom member having an inlet port is provided, and a part of the bottom member facing the opening of the circulating liquid inlet port is provided with a flow dividing projection protruding toward the circulating liquid inlet port, Guide ridges extending in the circumferential direction of the bottom member are provided on both sides of the flow dividing projection in the circumferential direction of the bottom member.
 本態様に従う構造とされた熱交換器によれば、循環液入口ポートから底部材の内側へ導入された循環液は、分流突起に接触することで、分流突起の両側に分かれて、ガイド突条に沿って底部材の周方向へ流れる。分流突起によって循環液の流れが周方向の両側に分けられることにより、分流突起がない場合に比して、循環液が底部材の内側をスムーズに流れて、循環液の流速の低下、換言すれば圧力損失が低減される。それ故、循環液入口ポートから底部材の内側へ流れ込んだ循環液が熱交換部へスムーズに流れて、熱交換部への循環液の効率的な供給が実現される。 According to the heat exchanger having the structure according to the present aspect, the circulating liquid introduced from the circulating liquid inlet port to the inside of the bottom member is divided into both sides of the flow dividing protrusion by contacting the flow dividing protrusion, and the guide protrusions are provided. Along the circumferential direction of the bottom member. Since the flow of the circulating liquid is divided into both sides in the circumferential direction by the flow dividing projections, the flow of the circulating liquid flows more smoothly inside the bottom member than in the case where there is no flow dividing protrusion, and thus the flow velocity of the circulating liquid decreases. For example, pressure loss is reduced. Therefore, the circulating liquid flowing from the circulating liquid inlet port to the inside of the bottom member smoothly flows to the heat exchanging portion, and the circulating liquid is efficiently supplied to the heat exchanging portion.
 本発明によれば、空気が調温後液室内に留まり難く、空気を効率的に除去することが可能となる。 According to the present invention, it is difficult for air to stay in the liquid chamber after temperature adjustment, and it is possible to efficiently remove air.
本発明の第1の実施形態としての熱交換器を示す斜視図The perspective view which shows the heat exchanger as the 1st Embodiment of this invention. 図1に示す熱交換器の正面図Front view of the heat exchanger shown in FIG. 図2に示す熱交換器の右側面図Right side view of the heat exchanger shown in FIG. 図2に示す熱交換器の平面図Plan view of the heat exchanger shown in FIG. 図2に示す熱交換器の底面図Bottom view of the heat exchanger shown in FIG. 図3のVI-VI断面図VI-VI sectional view of FIG. 図6のVII-VII断面図VII-VII sectional view of FIG. 図1に示す熱交換器を構成する底部材の斜視図1 is a perspective view of a bottom member constituting the heat exchanger shown in FIG. 図8に示す底部材の拡大平面図An enlarged plan view of the bottom member shown in FIG. 図9に示す底部材の断面図であって、図9のX-X断面に相当する図FIG. 10 is a cross-sectional view of the bottom member shown in FIG. 9, corresponding to the XX cross section of FIG. 9. 図7に示す熱交換器の要部を拡大して示す図The figure which expands and shows the principal part of the heat exchanger shown in FIG. 図1に示す熱交換器を構成する第2の液室壁部材の斜視図1 is a perspective view of a second liquid chamber wall member that constitutes the heat exchanger shown in FIG. 図11に示す第2の液室壁部材の拡大断面図Enlarged sectional view of the second liquid chamber wall member shown in FIG.
 以下、本発明の実施形態について、図面を参照しつつ説明する。 Hereinafter, embodiments of the present invention will be described with reference to the drawings.
 図1~5には、本発明の第1の実施形態としての熱交換器10が示されている。熱交換器10は、循環液と熱交換媒体が間接的に接して熱の授受を行う表面熱交換器であって、図6,7に示すように、ハウジング12に熱交換部14が収容された構造を有している。以下の説明において、上下方向とは、原則として、鉛直上下方向である図2中の上下方向を言う。 1 to 5 show a heat exchanger 10 as a first embodiment of the present invention. The heat exchanger 10 is a surface heat exchanger in which the circulating liquid and the heat exchange medium are indirectly in contact with each other to exchange heat. As shown in FIGS. 6 and 7, the heat exchange section 14 is housed in the housing 12. It has a different structure. In the following description, the vertical direction means the vertical direction in FIG. 2, which is the vertical vertical direction in principle.
 より詳細には、ハウジング12は、硬質の合成樹脂で形成されており、全体として筒状とされたハウジング本体16と、ハウジング本体16の下側の開口を塞ぐ底部材18と、ハウジング本体16の上側の開口を塞ぐ蓋部材20とによって構成されている。なお、ハウジング12の形成材料は、特に限定されるものではなく、金属やガラスなどであってもよいが、好適には、ポリカーボネートやアクリル樹脂などの合成樹脂で形成されており、ハウジング12の内部空間を目視で確認可能となるように透明乃至は半透明であることが望ましい。また、ハウジング12の全体が同じ材料で形成されている必要はなく、例えば、ハウジング本体16と底部材18と蓋部材20が異なる材料で形成されていてもよい。 More specifically, the housing 12 is formed of a hard synthetic resin, and has a generally cylindrical housing body 16, a bottom member 18 that closes an opening on the lower side of the housing body 16, and a housing body 16. It is constituted by a lid member 20 that closes the upper opening. The material for forming the housing 12 is not particularly limited, and may be metal or glass, but is preferably made of a synthetic resin such as polycarbonate or acrylic resin. It is desirable that the space is transparent or translucent so that the space can be visually confirmed. Further, the entire housing 12 does not need to be formed of the same material, and for example, the housing body 16, the bottom member 18, and the lid member 20 may be formed of different materials.
 ハウジング本体16は、円筒状とされた収容筒部22と、収容筒部22の周壁部につながる熱交換媒体入口ポート24および熱交換媒体出口ポート26とを、一体で備えている。収容筒部22の周壁部には、貯血槽などの外部装置に接続される接続部として、外周面に突出する取付突部28a,28bが設けられている。熱交換媒体入口ポート24と熱交換媒体出口ポート26は、何れも略円筒形状とされており、収容筒部22の下部から収容筒部22の径方向の両側へ向けて延び出していると共に、先端側に向けて下傾している。さらに、熱交換媒体入口ポート24の内腔と熱交換媒体出口ポート26の内腔は、何れも収容筒部22の内腔に連通されている。なお、収容筒部22は、円筒状に限定されるものではなく、楕円筒状や多角筒状、異形筒状などであってもよい。また、熱交換媒体入口ポート24と熱交換媒体出口ポート26は、円筒状に限定されるものではなく、楕円筒状や多角筒状、異形筒状などであってもよい。また、熱交換媒体入口ポート24と熱交換媒体出口ポート26は、ハウジング本体16と別体で設けられていてもよい。さらに、熱交換媒体入口ポート24と熱交換媒体出口ポート26は、相互に入れ替えた位置に設けられ得る。また、熱交換媒体入口ポート24及び熱交換媒体出口ポート26は、収容筒部22とは別体で形成されて収容筒部22の周壁部に取り付けられることで設けられていても良い。 The housing main body 16 integrally includes a cylindrical housing tubular portion 22, and a heat exchange medium inlet port 24 and a heat exchange medium outlet port 26 that are connected to the peripheral wall portion of the housing tubular portion 22. On the peripheral wall portion of the accommodating cylinder portion 22, mounting projections 28a and 28b protruding on the outer peripheral surface are provided as connection portions connected to an external device such as a blood reservoir. Each of the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 has a substantially cylindrical shape, and extends from the lower portion of the storage tubular portion 22 toward both sides in the radial direction of the storage tubular portion 22, and Inclined toward the tip side. Further, both the inner cavity of the heat exchange medium inlet port 24 and the inner cavity of the heat exchange medium outlet port 26 are communicated with the inner cavity of the housing tubular portion 22. The housing cylinder portion 22 is not limited to a cylindrical shape, and may be an elliptic cylinder shape, a polygonal cylinder shape, a deformed cylinder shape, or the like. Further, the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 are not limited to the cylindrical shape, and may be an elliptic cylinder shape, a polygonal cylinder shape, a deformed cylinder shape, or the like. Further, the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 may be provided separately from the housing body 16. Further, the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 may be provided in mutually interchanged positions. Further, the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 may be provided by being formed separately from the housing tubular portion 22 and attached to the peripheral wall portion of the housing tubular portion 22.
 底部材18は、図5~10に示すように、略円板形状乃至は有底円筒形状とされており、外周部分がハウジング本体16の下端部に全周に亘って液密に固着されている。本実施形態では、底部材18からハウジング本体16の収容筒部22に向けて突出する突起が、収容筒部22の下端面に開口する凹部に嵌め合わされて固着されている。 As shown in FIGS. 5 to 10, the bottom member 18 has a substantially disk shape or a bottomed cylindrical shape, and the outer peripheral portion is liquid-tightly fixed to the lower end portion of the housing body 16 over the entire circumference. There is. In the present embodiment, the protrusion projecting from the bottom member 18 toward the housing tubular portion 22 of the housing body 16 is fitted and fixed to the recess opening in the lower end surface of the housing tubular portion 22.
 さらに、底部材18には、循環液入口ポート30が設けられている。循環液入口ポート30は、略円筒形状とされて、底部材18から前方(図7中の左方)へ延び出しており、底部材18のハウジング本体16への装着状態において、循環液入口ポート30の内腔がハウジング本体16における収容筒部22の内腔に連通されている。 Further, the bottom member 18 is provided with a circulating liquid inlet port 30. The circulating liquid inlet port 30 has a substantially cylindrical shape and extends forward (leftward in FIG. 7) from the bottom member 18, and when the bottom member 18 is attached to the housing body 16, the circulating liquid inlet port 30 is provided. The inner cavity of 30 communicates with the inner cavity of the housing cylinder portion 22 of the housing body 16.
 更にまた、底部材18には、薬液投与ポート32が設けられている。この薬液投与ポート32は、底部材18の底壁部から前方へ傾斜しながら斜め下方へ向けて延び出しており、底部材18のハウジング本体16への装着状態において、薬液投与ポート32の内腔がハウジング本体16における収容筒部22の内腔に連通されている。なお、図7では、薬液投与ポート32が着脱可能なキャップ34によって塞がれている。 Furthermore, the bottom member 18 is provided with a drug solution administration port 32. The drug solution administration port 32 extends obliquely downward from the bottom wall portion of the bottom member 18 while inclining forward, and when the bottom member 18 is attached to the housing body 16, the inner cavity of the drug solution administration port 32. Is communicated with the inner cavity of the housing cylinder portion 22 of the housing body 16. Note that in FIG. 7, the drug solution administration port 32 is closed by a removable cap 34.
 底部材18は、図8~10に示すように、循環液入口ポート30の開口部分から径方向に延びる溝部36を備えている。溝部36は、底部材18の底壁部の上面に開口しており、溝部36の幅方向両側には、溝部36の底面よりも上側に位置する底上部38がそれぞれ設けられている。要するに、底部材18は、周壁の上端からの深さ寸法が、溝部36において、溝部36を外れた底上部38,38よりも大きくなっている。溝部36は、上下方向における底面の位置が長さ方向で略一定とされている。底上部38の上面は、循環液入口ポート30から離れるにしたがって下傾している。それ故、溝部36の底上部38からの深さ寸法は、循環液入口ポート30から離れるにしたがって小さくなっている。 As shown in FIGS. 8 to 10, the bottom member 18 includes a groove portion 36 that extends radially from the opening of the circulating fluid inlet port 30. The groove portion 36 is open to the upper surface of the bottom wall portion of the bottom member 18, and bottom upper portions 38 located above the bottom surface of the groove portion 36 are provided on both sides in the width direction of the groove portion 36, respectively. In short, the depth dimension from the upper end of the peripheral wall of the bottom member 18 is larger in the groove portion 36 than in the bottom upper portions 38, 38 which are out of the groove portion 36. The position of the bottom surface of the groove portion 36 in the vertical direction is substantially constant in the length direction. The upper surface of the bottom upper portion 38 is inclined downward as it goes away from the circulating liquid inlet port 30. Therefore, the depth of the groove 36 from the bottom upper portion 38 becomes smaller as the distance from the circulating liquid inlet port 30 increases.
 溝部36の一方の端部に循環液入口ポート30が開口していると共に、溝部36の他方の端部に分流突起40が設けられている。分流突起40は、底部材18の周壁部における循環液入口ポート30の開口との対向部分において、循環液入口ポート30に向けて溝部36の長さ方向で突出している。分流突起40は、先端に向けて底部材18の周方向での幅寸法が次第に小さくなっている。特に、先端部分が外側(突出先端側)へ向けて凸の湾曲形状とされていると共に、基端部分が外側(周方向両側)へ向けて凹の湾曲形状とされている。分流突起40の下端が底部材18の溝部36の底面に連続していると共に、分流突起40の上端が底上部38,38よりも上側まで達している。 The circulating fluid inlet port 30 is opened at one end of the groove 36, and the flow dividing projection 40 is provided at the other end of the groove 36. The flow dividing projection 40 projects in the longitudinal direction of the groove 36 toward the circulating liquid inlet port 30 at a portion of the peripheral wall portion of the bottom member 18 facing the opening of the circulating liquid inlet port 30. The width dimension of the flow dividing projection 40 in the circumferential direction of the bottom member 18 gradually decreases toward the tip. In particular, the tip end portion has a convex curved shape toward the outside (projecting tip end side), and the base end portion has a concave curved shape toward the outside (both circumferential directions). The lower end of the flow dividing projection 40 is continuous with the bottom surface of the groove portion 36 of the bottom member 18, and the upper end of the flow dividing projection 40 reaches the upper side of the bottom upper portions 38, 38.
 底上部38,38には、それぞれガイド突条42が設けられている。ガイド突条42は、底上部38の上面からそれぞれ上側へ向けて突出する突条であって、分流突起40の両側から循環液入口ポート30側へ向けて、底部材18の周方向に所定の長さで延びている。ガイド突条42の周方向一方の端部は、分流突起40に対して周方向に離れて位置していると共に、ガイド突条42の周方向他方の端部は、循環液入口ポート30の開口に対して周方向に離れて位置している。ガイド突条42は、底部材18の周壁内面に対して内周側に離れて対向するように設けられている。底上部38の上面が分流突起40側に向けて下傾していると共に、ガイド突条42の上端が上下方向と略直交して延びていることから、ガイド突条42の底上部38からの突出高さ寸法が、分流突起40側から循環液入口ポート30側に向けて次第に小さくなっている。循環液は、循環液入口ポート30から底部材18内へ流れ込んで、分流突起40に衝突した後、ガイド突条42に沿って流れ、循環液入口ポート30側へ導かれる。このように構成することで、循環液の流れが妨げられず、底部材18内を循環液で効率的に満たすことができる。なお、ガイド突条42の上面は、上下方向において、分流突起40の上面と略同じ高さに位置している。 Guide ridges 42 are provided on the upper portions 38, 38 of the bottom, respectively. The guide ridges 42 are ridges that project upward from the upper surface of the bottom upper portion 38, respectively, and extend in predetermined directions in the circumferential direction of the bottom member 18 from both sides of the flow dividing projection 40 toward the circulating liquid inlet port 30 side. It extends in length. One end of the guide ridge 42 in the circumferential direction is located apart from the flow dividing projection 40 in the circumferential direction, and the other end of the guide ridge 42 in the circumferential direction is an opening of the circulating fluid inlet port 30. It is located in the circumferential direction with respect to. The guide ridges 42 are provided so as to face the inner surface of the peripheral wall of the bottom member 18 while being spaced apart from each other on the inner peripheral side. Since the upper surface of the bottom upper part 38 is inclined downward toward the diversion projection 40 side, and the upper end of the guide protrusion 42 extends substantially perpendicular to the vertical direction, The projecting height dimension gradually decreases from the flow dividing projection 40 side toward the circulating liquid inlet port 30 side. The circulating liquid flows into the bottom member 18 from the circulating liquid inlet port 30, collides with the flow dividing projection 40, then flows along the guide protrusion 42, and is guided to the circulating liquid inlet port 30 side. With this configuration, the flow of the circulating liquid is not obstructed, and the bottom member 18 can be efficiently filled with the circulating liquid. The upper surface of the guide ridge 42 is located at substantially the same height as the upper surface of the flow dividing projection 40 in the vertical direction.
 蓋部材20は、図7,11に示すように、全体として上下逆向きの有底円筒形状とされていると共に、本実施形態では、上底壁部および周壁部において相互に固着された分割された2部材によって構成されている。すなわち、本実施形態の蓋部材20は、ハウジング本体16の上端部に固着される第1の液室壁部材44と、第1の液室壁部材44に固着される第2の液室壁部材46とによって構成されている。 As shown in FIGS. 7 and 11, the lid member 20 has a bottomed cylindrical shape that is turned upside down as a whole, and in this embodiment, is divided into upper and lower wall portions and a peripheral wall portion that are fixed to each other. It is composed of two members. That is, the lid member 20 of the present embodiment includes the first liquid chamber wall member 44 fixed to the upper end portion of the housing body 16 and the second liquid chamber wall member fixed to the first liquid chamber wall member 44. And 46.
 第1の液室壁部材44は、下端部がハウジング本体16の上端部に対して溶着などの手段で固着されていると共に、前方(図11中の左方)において斜め上方に向けて開口する傾斜開口部48を備えている。この傾斜開口部48の周囲は、上方に向けて後方へ傾斜する平面状とされている。 The lower end of the first liquid chamber wall member 44 is fixed to the upper end of the housing body 16 by means such as welding, and the first liquid chamber wall member 44 opens obliquely upward at the front (left in FIG. 11). An inclined opening 48 is provided. The periphery of the inclined opening portion 48 is a flat surface that is inclined rearward toward the upper side.
 さらに、第1の液室壁部材44の上側の壁部には、略円筒形状の脱気ポート50が設けられており、脱気ポート50の下側の開口52が第1の液室壁部材44の上側の壁内面に形成されて、脱気ポート50の内腔が第1の液室壁部材44の内部空間(後述する脱気前液室80)に連通されている。脱気ポート50の開口52の周縁部分は、下側に向かって次第に拡開する湾曲面形状乃至傾斜平面形状等のテーパ形状とされる部分を含んでいても良い。これにより、後述する気泡の脱気ポート50への案内が、後述するフィルタ78だけでなく、脱気ポート50の開口周縁部分のテーパ形状によっても効率的に実現される。なお、脱気ポート50の開口52にテーパ面が設けられる場合には、テーパ面が後述するフィルタ78から連続する位置まで設けられていても良いし、上下方向と略直交する平面を介してフィルタ78から離れた位置にテーパ面が設けられていても良い。図7,11では、脱気ポート50が着脱可能なキャップ54によって塞がれている。 Further, the upper wall portion of the first liquid chamber wall member 44 is provided with a substantially cylindrical degassing port 50, and the lower opening 52 of the degassing port 50 has a first liquid chamber wall member. It is formed on the inner wall surface of the upper side of 44, and the inner cavity of the degassing port 50 communicates with the internal space of the first liquid chamber wall member 44 (pre-degassing liquid chamber 80 described later). The peripheral portion of the opening 52 of the degassing port 50 may include a tapered portion such as a curved surface shape or an inclined flat surface shape that gradually expands downward. Thereby, the guide of bubbles to the degassing port 50 described later is efficiently realized not only by the filter 78 described below, but also by the tapered shape of the opening peripheral edge portion of the degassing port 50. When the opening 52 of the degassing port 50 is provided with a tapered surface, the tapered surface may be provided up to a position continuous with the filter 78 described later, or the filter may be provided through a plane substantially orthogonal to the vertical direction. A tapered surface may be provided at a position away from 78. In FIGS. 7 and 11, the degassing port 50 is closed by a removable cap 54.
 更にまた、図6に示すように、第1の液室壁部材44の周壁部には、略円筒形状の圧力検出ポート56が設けられており、圧力検出ポート56の内腔が第1の液室壁部材44の内部空間に連通されていると共に、圧力検出ポート56の外周面には雄ネジが設けられている。圧力検出ポート56は、圧力検出ポート56の外周面の雄ネジに対応する雌ネジを有するキャップが取り付けられていてもよい。 Furthermore, as shown in FIG. 6, a substantially cylindrical pressure detection port 56 is provided on the peripheral wall portion of the first liquid chamber wall member 44, and the inner cavity of the pressure detection port 56 is the first liquid. A male screw is provided on the outer peripheral surface of the pressure detection port 56 while communicating with the internal space of the chamber wall member 44. The pressure detection port 56 may be attached with a cap having a female screw corresponding to the male screw on the outer peripheral surface of the pressure detection port 56.
 また、蓋部材20は、内部空間を外部から目視で確認することが可能とされるために、好適には少なくとも脱気ポート50の基端部(根元部分)が透明にされていることが好ましい。本実施形態では、ハウジング12の全体が透明とされているが、ハウジング本体16と底部材18と蓋部材20とが不透明とされていてもよい。また、蓋部材20には、シボ加工が施され得る。また、第1の液室壁部材44を透明とし、第2の液室壁部材46を不透明にする等、各々の部材によって透明性を異ならせて構成してもよい。 Further, in the lid member 20, it is preferable that at least the base end portion (root portion) of the degassing port 50 is made transparent so that the internal space can be visually confirmed from the outside. . In the present embodiment, the entire housing 12 is transparent, but the housing body 16, the bottom member 18, and the lid member 20 may be opaque. In addition, the lid member 20 may be subjected to embossing. Further, the first liquid chamber wall member 44 may be made transparent, and the second liquid chamber wall member 46 may be made opaque.
 第2の液室壁部材46は、図12,13にも示すように、前方へ延び出す略円筒形状の循環液出口ポート58を備えており、循環液出口ポート58の内腔が第2の液室壁部材46の内部空間に連通されている。更にまた、第2の液室壁部材46には、温度検出ポート60が設けられており、温度検出ポート60に温度検出部材62が挿通状態で設けられている。温度検出部材62は、筒状の基部64が温度検出ポート60において第2の液室壁部材46に固定されていると共に、試験管状の先端部66が温度検出ポート60を通じて後述する脱気後液室82へ差し入れられており、脱気後液室82内の循環液の温度を測定可能とされている。 As shown in FIGS. 12 and 13, the second liquid chamber wall member 46 includes a circulating fluid outlet port 58 having a substantially cylindrical shape that extends forward, and the inner cavity of the circulating fluid outlet port 58 is the second. It communicates with the internal space of the liquid chamber wall member 46. Furthermore, the temperature detecting port 60 is provided in the second liquid chamber wall member 46, and the temperature detecting member 62 is provided in the temperature detecting port 60 in an inserted state. In the temperature detecting member 62, a tubular base 64 is fixed to the second liquid chamber wall member 46 at the temperature detecting port 60, and a test tube-shaped tip 66 is passed through the temperature detecting port 60 and the degassed liquid to be described later. It is inserted into the chamber 82, and the temperature of the circulating liquid in the liquid chamber 82 after deaeration can be measured.
 この第2の液室壁部材46が第1の液室壁部材44の傾斜開口部48を塞ぐように設けられており、第2の液室壁部材46が第1の液室壁部材44に対して液密に固着されることによって、蓋部材20が形成されている。本実施形態では、第1の液室壁部材44における傾斜開口部48に設けられた突起が、第2の液室壁部材46に設けられた凹部に嵌め合わされて固着されている。 The second liquid chamber wall member 46 is provided so as to close the inclined opening portion 48 of the first liquid chamber wall member 44, and the second liquid chamber wall member 46 serves as the first liquid chamber wall member 44. The lid member 20 is formed by being liquid-tightly fixed. In the present embodiment, the projection provided on the inclined opening portion 48 of the first liquid chamber wall member 44 is fitted and fixed to the concave portion provided on the second liquid chamber wall member 46.
 そして、蓋部材20は、第1の液室壁部材44で構成された下端部が、ハウジング本体16の上端部に対して液密に固着されている。本実施形態では、第1の液室壁部材44の下端部に設けられた突起が、ハウジング本体16の上端面に開口する凹部に嵌め合わされて固着されている。 The lower end portion of the lid member 20, which is constituted by the first liquid chamber wall member 44, is liquid-tightly fixed to the upper end portion of the housing body 16. In the present embodiment, the projection provided on the lower end of the first liquid chamber wall member 44 is fitted and fixed to the recess opening on the upper end surface of the housing body 16.
 このように、底部材18がハウジング本体16における収容筒部22の下側を覆うように取り付けられると共に、蓋部材20が収容筒部22の上側を覆うように取り付けられることにより、図6,7に示すように、中空構造のハウジング12がハウジング本体16と底部材18と蓋部材20とによって構成されている。なお、底部材18の循環液入口ポート30と薬液投与ポート32、ハウジング本体16の熱交換媒体入口ポート24と熱交換媒体出口ポート26、更に蓋部材20の循環液出口ポート58と脱気ポート50と温度検出ポート60と圧力検出ポート56とが、何れもハウジング12の内部空間に連通されている。 Thus, the bottom member 18 is attached so as to cover the lower side of the housing cylindrical portion 22 in the housing body 16, and the lid member 20 is attached so as to cover the upper side of the housing cylindrical portion 22. As shown in FIG. 1, the hollow housing 12 is composed of a housing body 16, a bottom member 18, and a lid member 20. The circulating liquid inlet port 30 and the chemical liquid injection port 32 of the bottom member 18, the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 of the housing body 16, and the circulating liquid outlet port 58 and the degassing port 50 of the lid member 20. The temperature detection port 60 and the pressure detection port 56 are all in communication with the internal space of the housing 12.
 かくの如き構造とされたハウジング12の内部空間には、熱交換部14が収容されている。熱交換部14は、図6,7,11に示すように、複数の伝熱管68を備えている。伝熱管68は、細長い小径の円筒形状とされており、後述する循環液および熱交換媒体に対する耐食性に優れているとともに熱伝導率が大きい材料で形成されることが望ましく、例えば、銅やアルミニウム、鉄(ステンレス鋼)或いはそれらの合金などによって形成されている。また、本実施形態の伝熱管68は、上下方向に直線的に延びていることで、伝熱管68の内腔への空気の残留の防止や、伝熱管68の内腔を流れる循環液の乱流の低減などが図られている。尤も、伝熱管68は、直線的な筒状に限定されず、例えば、適宜に湾曲することで、後述する熱交換媒体との接触面積を大きく得て、熱交換の効率向上を図ることもできる。さらに、伝熱管68の断面形状や数、配置などは、何れも限定されるものではなく、例えば、楕円筒状や多角筒状、異形筒状などであってもよい。更にまた、例えば、伝熱管68の外周面にフィンを設けて熱交換の効率向上を図ることもできる。 The heat exchange section 14 is housed in the internal space of the housing 12 having such a structure. The heat exchange section 14 includes a plurality of heat transfer tubes 68, as shown in FIGS. The heat transfer tube 68 has an elongated small-diameter cylindrical shape, and is preferably formed of a material having excellent corrosion resistance to a circulating fluid and a heat exchange medium described later and having a large thermal conductivity. For example, copper or aluminum, It is formed of iron (stainless steel) or an alloy thereof. Further, since the heat transfer tube 68 of the present embodiment extends linearly in the vertical direction, it is possible to prevent air from remaining in the lumen of the heat transfer tube 68 and to disturb the circulating fluid flowing through the lumen of the heat transfer tube 68. The flow is being reduced. However, the heat transfer tube 68 is not limited to a linear tubular shape, and can be appropriately curved, for example, to obtain a large contact area with a heat exchange medium described later to improve the efficiency of heat exchange. .. Furthermore, the cross-sectional shape, number, arrangement, etc. of the heat transfer tubes 68 are not limited to any one, and may be, for example, an elliptic cylinder shape, a polygonal cylinder shape, or a deformed cylinder shape. Furthermore, for example, fins may be provided on the outer peripheral surface of the heat transfer tube 68 to improve the efficiency of heat exchange.
 さらに、伝熱管68は、複数が略円柱状に束ねられた状態の管群として配されており、それら複数の伝熱管68の下端部分がウレタン等で形成される下支持板70によって相互に位置決めされていると共に、上端部分がウレタン等で形成される上支持板72によって相互に位置決めされている。下支持板70と上支持板72は、何れも合成樹脂などで形成された略円板形状の部材であって、管群における複数の伝熱管68の間を液密に塞いでいると共に、管群の外周へ突出してハウジング本体16に固着されている。なお、支持板70,72は、伝熱管68の挿通孔を備える形状で成形した後で、伝熱管68を挿通孔に差し入れて接着などしてもよいが、例えば、伝熱管68を収容筒部22の内周へセットした状態で、収容筒部22の軸方向両端部の内周にポッティング樹脂を充填して成形することで、伝熱管68および収容筒部22に固着された状態で形成することもできる。 Further, the heat transfer tubes 68 are arranged as a tube group in which a plurality of heat transfer tubes 68 are bundled in a substantially columnar shape, and the lower end portions of the plurality of heat transfer tubes 68 are positioned relative to each other by a lower support plate 70 formed of urethane or the like. In addition, the upper end portions are mutually positioned by the upper support plate 72 formed of urethane or the like. Each of the lower support plate 70 and the upper support plate 72 is a substantially disc-shaped member formed of a synthetic resin or the like, and liquid-tightly closes the space between the plurality of heat transfer pipes 68 in the tube group. It projects to the outer periphery of the group and is fixed to the housing body 16. Note that the support plates 70 and 72 may be formed into a shape having an insertion hole for the heat transfer tube 68, and then the heat transfer tube 68 may be inserted into the insertion hole and adhered thereto. While being set on the inner circumference of the housing 22, the inner circumference of both axial ends of the housing cylinder 22 is filled with a potting resin to be molded, so that the heat transfer tube 68 and the housing cylinder 22 are fixedly formed. You can also
 そして、下支持板70が収容筒部22の下端部に固定されると共に、上支持板72が収容筒部22の上端部に固定されることにより、複数の伝熱管68が収容筒部22の内周において上下に延びるように支持されている。これにより、伝熱管68は、下開口が底部材18の内部空間を通じて循環液入口ポート30および薬液投与ポート32に連通されていると共に、上開口が蓋部材20の内部空間を通じて循環液出口ポート58および脱気ポート50に連通されている。 Then, the lower support plate 70 is fixed to the lower end portion of the housing tubular portion 22, and the upper support plate 72 is fixed to the upper end portion of the housing tubular portion 22, so that the plurality of heat transfer tubes 68 are arranged in the housing tubular portion 22. It is supported so as to extend vertically in the inner circumference. As a result, the heat transfer tube 68 has a lower opening communicating with the circulating liquid inlet port 30 and the chemical liquid administration port 32 through the internal space of the bottom member 18, and an upper opening through the internal space of the lid member 20. And the deaeration port 50.
 ハウジング本体16における収容筒部22の内周面は、上方に向けて次第に収縮しており、本実施形態では、次第に小径となるテーパ形状とされている。これにより、収容筒部22の内周面と複数の伝熱管68からなる管群の外周面との対向面間距離が、上方へ行くに従って小さくなっている。 The inner peripheral surface of the housing tubular portion 22 of the housing body 16 gradually contracts upward, and in the present embodiment, has a tapered shape with a gradually decreasing diameter. Thereby, the distance between the facing surfaces of the inner peripheral surface of the housing tubular portion 22 and the outer peripheral surface of the tube group including the plurality of heat transfer tubes 68 becomes smaller as it goes upward.
 さらに、熱交換媒体入口ポート24と熱交換媒体出口ポート26が、複数の伝熱管68の間を通じて相互に連通されていると共に、それら伝熱管68の間の空間は、底部材18および蓋部材20の内部空間(後述する調温前液室74および調温後液室76)に対して支持板70,72で液密に隔てられている。 Further, the heat exchange medium inlet port 24 and the heat exchange medium outlet port 26 are communicated with each other through the plurality of heat transfer tubes 68, and the space between the heat transfer tubes 68 has a bottom member 18 and a lid member 20. The inner spaces (the pre-temperature-control liquid chamber 74 and the post-temperature-control liquid chamber 76) are liquid-tightly separated by the support plates 70 and 72.
 このように熱交換部14がハウジング12に収容されることで、熱交換部14の下側には、壁部が底部材18と下支持板70で構成された調温前液室74が形成されていると共に、熱交換部14の上側には、壁部が蓋部材20と上支持板72で構成された調温後液室76が形成されている。 Since the heat exchange section 14 is housed in the housing 12 in this manner, a pre-temperature-control liquid chamber 74 having a wall portion composed of the bottom member 18 and the lower support plate 70 is formed below the heat exchange section 14. In addition, on the upper side of the heat exchange section 14, a temperature-adjusted liquid chamber 76 having a wall portion constituted by the lid member 20 and the upper support plate 72 is formed.
 調温前液室74は、底部材18の内部空間によって構成されており、循環液入口ポート30と薬液投与ポート32が連通されていると共に、複数の伝熱管68の各内腔の下端が連通されている。 The pre-temperature-controlling liquid chamber 74 is configured by the internal space of the bottom member 18, the circulating liquid inlet port 30 and the chemical liquid administration port 32 are communicated with each other, and the lower ends of the inner cavities of the plurality of heat transfer tubes 68 are communicated with each other. Has been done.
 調温後液室76は、蓋部材20の内部空間によって構成されており、脱気ポート50と圧力検出ポート56と循環液出口ポート58と温度検出ポート60とが連通されていると共に、複数の伝熱管68の各内腔が連通されている。なお、温度検出ポート60に差し通された温度検出部材62は、先端部66が調温後液室76内へ突出している。 The temperature-adjusted liquid chamber 76 is constituted by the internal space of the lid member 20, and the deaeration port 50, the pressure detection port 56, the circulating liquid outlet port 58, and the temperature detection port 60 are connected to each other, and a plurality of them are provided. The lumens of the heat transfer tube 68 communicate with each other. The temperature detecting member 62 inserted into the temperature detecting port 60 has a tip portion 66 protruding into the liquid chamber 76 after temperature adjustment.
 ここにおいて、調温後液室76には、フィルタ78が配設されている。フィルタ78は、循環液の通過を許容するとともに空気の通過を制限する高分子膜であって、本実施形態では、平坦なメンブラン状とされて、調温後液室76において傾斜して上下に広がるように展張状態で配置されている。より具体的には、フィルタ78は、図11に示すように、第1の液室壁部材44の傾斜開口部48を塞いで設けられており、下方から上方へ向けて脱気ポート50の開口52へ近づくように後方(図11中、右方)へ傾斜して広がっている。これにより、フィルタ78は、全周縁が調温後液室76を画成する壁部で固定的に支持されており、特に下端部が調温後液室76の筒状周壁の下側部分によって支持されていると共に、上端部が調温後液室76の上底の壁部分によって支持されている。なお、図7,11では、見易さのために、フィルタ78の厚さを実際よりも厚く図示している。 Here, a filter 78 is arranged in the temperature-adjusted liquid chamber 76. The filter 78 is a polymer film that allows passage of the circulating liquid and restricts the passage of air. In the present embodiment, the filter 78 has a flat membrane shape and is tilted up and down in the liquid chamber 76 after temperature adjustment. It is arranged in a stretched state so as to spread. More specifically, as shown in FIG. 11, the filter 78 is provided so as to close the inclined opening portion 48 of the first liquid chamber wall member 44, and the opening of the degassing port 50 from the bottom to the top. It is inclined and spreads backward (to the right in FIG. 11) so as to approach 52. As a result, the filter 78 is fixedly supported by the wall portion that defines the temperature-adjusted liquid chamber 76 at the entire peripheral edge thereof, and particularly, the lower end portion is supported by the lower portion of the cylindrical peripheral wall of the temperature-adjusted liquid chamber 76. In addition to being supported, the upper end portion is supported by the wall portion of the upper bottom of the liquid chamber 76 after temperature adjustment. Note that, in FIGS. 7 and 11, the thickness of the filter 78 is illustrated thicker than it actually is for the sake of easy viewing.
 本実施形態のフィルタ78は、第1の液室壁部材44の成形時に、第1の液室壁部材44の金型に予めセットされてインサート成形されており、第1の液室壁部材44のインサート成形品を構成するインサート構成部材とされている。そして、フィルタ78は、第1の液室壁部材44に対して、フィルタ78の周縁が溶着されたり内部に差し入れられた状態で固着されて、一体的に取り付けられている。これにより、フィルタ78は、ハウジング12を構成する第1の液室壁部材44における傾斜開口部48の開口周縁部に対して、外周縁が全周に亘って直接固着されている。その結果、フィルタ78と第1の液室壁部材44の間に段差や凹凸などが形成され難くなっている。さらに、第1の液室壁部材44に対して固着される第2の液室壁部材46に対するフィルタ78の配設部分にも段差や凹凸が形成され難い。要するに、調温後液室76の壁内面においてフィルタ78を支持するための段差や凹凸が不要とされており、後述するプライミング処理の完了後に、調温後液室76に空気が残留し難くなっている。 The filter 78 of the present embodiment is set in the mold of the first liquid chamber wall member 44 in advance and insert-molded when the first liquid chamber wall member 44 is molded. It is an insert constituent member that constitutes the insert molded article. The filter 78 is fixedly attached to the first liquid chamber wall member 44 in a state where the peripheral edge of the filter 78 is welded or inserted inside, and is integrally attached. As a result, the outer peripheral edge of the filter 78 is directly fixed to the opening peripheral edge portion of the inclined opening portion 48 of the first liquid chamber wall member 44 constituting the housing 12 over the entire circumference. As a result, it is difficult for a step or unevenness to be formed between the filter 78 and the first liquid chamber wall member 44. Further, it is difficult for a step or unevenness to be formed also in the portion where the filter 78 is provided with respect to the second liquid chamber wall member 46 that is fixed to the first liquid chamber wall member 44. In short, steps or irregularities for supporting the filter 78 are not required on the inner surface of the wall of the temperature-adjusted liquid chamber 76, and air is unlikely to remain in the temperature-adjusted liquid chamber 76 after completion of the priming process described later. ing.
 なお、フィルタ78の形成材料は、特に限定されないが、例えば、ポリエステルやポリアミド、ポリオレフィン、フッ素樹脂などの疎水性高分子材料で形成されることが望ましい。フィルタ78を疎水性の材料で形成することにより、気泡がフィルタ78に沿って移動し易くなって脱気ポート50へ効率的に案内されることから、空気の排出効率の向上が図られる。尤も、フィルタ78は親水性高分子材料で形成されていてもよく、フィルタ78が親水性材料で形成されていれば、循環液がより容易にフィルタ78を通過することができる。また、疎水性高分子材料で形成された薄膜の表面に親水化処理を施したり、親水性高分子材料で形成された薄膜の表面に疎水化処理を施すことによって、フィルタ78を得ることも可能である。フィルタ78は、要求される性能に応じて、親水性と疎水性を適宜に併せ持つようにもできる。 The material for forming the filter 78 is not particularly limited, but is preferably formed of a hydrophobic polymer material such as polyester, polyamide, polyolefin, or fluororesin. By forming the filter 78 with a hydrophobic material, bubbles easily move along the filter 78 and are efficiently guided to the degassing port 50, so that the air discharge efficiency is improved. However, the filter 78 may be made of a hydrophilic polymer material, and if the filter 78 is made of a hydrophilic material, the circulating liquid can easily pass through the filter 78. It is also possible to obtain the filter 78 by subjecting the surface of a thin film formed of a hydrophobic polymer material to a hydrophilic treatment or by subjecting the surface of a thin film formed of a hydrophilic polymer material to a hydrophobic treatment. Is. The filter 78 can also appropriately have both hydrophilicity and hydrophobicity depending on the required performance.
 そして、フィルタ78が調温後液室76に配されることにより、調温後液室76は、フィルタ78の両側に二分されている。すなわち、フィルタ78の後方には、複数の伝熱管68と脱気ポート50と圧力検出ポート56とが連通された脱気前液室80が形成されている一方、フィルタ78の前方には、循環液出口ポート58と温度検出ポート60が連通された脱気後液室82が形成されている。本実施形態では、蓋部材20において、脱気前液室80の壁部と脱気ポート50が第1の液室壁部材44において一体形成されていると共に、脱気後液室82の壁部と循環液出口ポート58が第2の液室壁部材46において一体形成されている。なお、圧力検出ポート56によって脱気前液室80内の圧力を図示しない圧力センサで測定することができると共に、温度検出部材62を備える温度検出ポート60によって脱気後液室82内の温度を測定することができる。 The temperature-adjusted liquid chamber 76 is divided into two parts on both sides of the filter 78 by disposing the filter 78 in the temperature-adjusted liquid chamber 76. That is, in the rear of the filter 78, the pre-degassing liquid chamber 80 in which the plurality of heat transfer pipes 68, the degassing port 50, and the pressure detection port 56 communicate with each other is formed, while in front of the filter 78, the circulation is performed. A post-degassing liquid chamber 82 is formed in which the liquid outlet port 58 and the temperature detection port 60 communicate with each other. In the present embodiment, in the lid member 20, the wall portion of the pre-degassing liquid chamber 80 and the degassing port 50 are integrally formed in the first liquid chamber wall member 44, and the wall portion of the post-degassing liquid chamber 82. The circulating liquid outlet port 58 is integrally formed in the second liquid chamber wall member 46. The pressure in the pre-degassing liquid chamber 80 can be measured by a pressure sensor (not shown) by the pressure detection port 56, and the temperature in the post-degassing liquid chamber 82 can be measured by the temperature detection port 60 including the temperature detection member 62. Can be measured.
 このような構造を有する本実施形態の熱交換器10は、循環液入口ポート30と循環液出口ポート58が図示しない体外循環回路に接続されると共に、熱交換媒体入口ポート24と熱交換媒体出口ポート26が図示しない熱交換媒体循環回路に接続された状態で、使用される。 In the heat exchanger 10 of the present embodiment having such a structure, the circulating fluid inlet port 30 and the circulating fluid outlet port 58 are connected to an extracorporeal circulation circuit (not shown), and the heat exchange medium inlet port 24 and the heat exchange medium outlet are provided. It is used with the port 26 connected to a heat exchange medium circulation circuit (not shown).
 体外循環回路は、心停止状態の患者に対して血液の循環と心筋保護液の投与を行うことで、酸素の供給と心筋の損傷防止とを図るものである。本実施形態の体外循環回路は、心臓および肺の機能を一時的に代替するための人工肺、熱交換器、送血用ポンプを組み込んだ回路と心筋保護液を心臓に注入する回路から成る。なお、循環液は、例えば、晶質性心筋保護液や血液、晶質性心筋保護液に血液を混合した血液添加心筋保護液などが好適に用いられる。晶質性心筋保護液の組成は、特に限定されないが、一般的に高カリウム溶液であって、心筋保護に必要とされる酸素を運搬する。また、本実施形態では、心筋保護回路用の熱交換器10を例示するが、本発明に係る熱交換器は、必ずしも心筋保護回路にのみ用いられるものではなく、例えば、患者を低体温状態とする際に用いられる人工心肺回路用の熱交換器にも適用され得る。 The extracorporeal circulation circuit aims to supply oxygen and prevent myocardial damage by circulating blood and administering cardioplegic solution to patients in cardiac arrest. The extracorporeal circulation circuit of the present embodiment includes a circuit incorporating an artificial lung for temporarily replacing the functions of the heart and lungs, a heat exchanger, a blood pump, and a circuit for injecting a cardioplegic solution into the heart. As the circulating fluid, for example, a crystalline cardioplegic solution, blood, a blood-added cardioplegic solution in which blood is mixed with a crystalline cardioplegic solution, and the like are preferably used. Although the composition of the crystalline cardioplegic solution is not particularly limited, it is generally a high potassium solution and carries oxygen required for cardioplegia. Further, in the present embodiment, the heat exchanger 10 for the myocardial protection circuit is exemplified, but the heat exchanger according to the present invention is not necessarily used only for the myocardial protection circuit, and for example, a patient is placed in a hypothermic state. It can also be applied to a heat exchanger for an artificial heart-lung circuit used when performing heat treatment.
 熱交換媒体循環回路は、熱交換媒体を循環させるためのポンプを備えていると共に、熱交換媒体を冷却又は加温するための調温装置を備えている。なお、熱交換媒体は、熱交換媒体循環回路を流動可能な流体であればよいが、好適には水などの液体が採用される。 The heat exchange medium circulation circuit includes a pump for circulating the heat exchange medium and a temperature control device for cooling or heating the heat exchange medium. The heat exchange medium may be any fluid that can flow through the heat exchange medium circulation circuit, but a liquid such as water is preferably used.
 熱交換器10を使用する際には、先ず、プライミング処理を行う。すなわち、循環液入口ポート30から循環液出口ポート58までを循環液で満たすことにより、循環液の循環経路上に位置する循環液入口ポート30、薬液投与ポート32、調温前液室74、複数の伝熱管68、調温後液室76、循環液出口ポート58、脱気ポート50、圧力検出ポート56を循環液で満たして空気を排出する。 When using the heat exchanger 10, firstly, a priming process is performed. That is, by filling the circulating fluid inlet port 30 to the circulating fluid outlet port 58 with the circulating fluid, the circulating fluid inlet port 30, the medicinal solution administration port 32, the pre-temperature regulating liquid chamber 74, and the plurality of circulating fluid inlet ports 30 located on the circulating path of the circulating fluid are provided. The heat transfer pipe 68, the temperature-adjusted liquid chamber 76, the circulating liquid outlet port 58, the degassing port 50, and the pressure detection port 56 are filled with the circulating liquid to discharge the air.
 具体的には、脱気ポート50を開放した状態で循環液入口ポート30から循環液を導入することにより、脱気前液室80が循環液で満たされるまで空気が脱気ポート50から外部へ排出される。さらに、脱気前液室80を満たす循環液内に混じった空気は、フィルタ78によって濾しとられて、気泡となってフィルタ78に沿って浮上することで、脱気前液室80の上側の壁部に設けられた脱気ポート50から外部へ排出される。また、フィルタ78を通じて脱気後液室82に循環液が入ることにより、脱気後液室82内の空気が循環液出口ポート58から図示しない体外循環回路へ排出されて、体外循環回路に設けられたエアトラップによって空気が循環回路外へ排出される。なお、図7,11では、脱気ポート50にキャップ54が取り付けられているが、キャップ54は、プライミング処理を行う際に取り外されて、脱気ポート50に図示しないチューブなどが接続された状態でプライミング処理が行われる。さらに、圧力検出ポート56は、図示しない圧力センサの挿通状態で、或いは圧力センサが挿通されていない状態で、液密に封止される。 Specifically, by introducing the circulating liquid from the circulating liquid inlet port 30 with the degassing port 50 opened, the air flows from the degassing port 50 to the outside until the pre-degassing liquid chamber 80 is filled with the circulating liquid. Is discharged. Further, the air mixed in the circulating fluid filling the pre-degassing liquid chamber 80 is filtered out by the filter 78, becomes air bubbles and floats up along the filter 78, so that the air above the pre-degassing liquid chamber 80 is removed. It is discharged to the outside from the deaeration port 50 provided on the wall. Further, when the circulating liquid enters the post-degassing liquid chamber 82 through the filter 78, the air in the post-degassing liquid chamber 82 is discharged from the circulating liquid outlet port 58 to an extracorporeal circulation circuit (not shown), and is provided in the extracorporeal circulation circuit. The air trap is discharged to the outside of the circulation circuit. 7 and 11, the cap 54 is attached to the deaeration port 50, but the cap 54 is removed when performing the priming process, and a tube or the like (not shown) is connected to the deaeration port 50. The priming process is performed in. Further, the pressure detection port 56 is liquid-tightly sealed when a pressure sensor (not shown) is inserted or when the pressure sensor is not inserted.
 ここにおいて、フィルタ78は、脱気ポート50へ向けて傾斜しており、より具体的には、上方に向けて脱気ポート50の開口52へ近づく向きに傾斜して設けられていることから、フィルタ78に沿って浮上した気泡が脱気ポート50へ導かれて、空気が脱気ポート50から外部へ効率的に排出される。それ故、プライミング処理後に空気が脱気前液室80内に留まり難く、循環液内の空気の除去を効果的に実現することができる。 Here, since the filter 78 is inclined toward the degassing port 50, and more specifically, is provided so as to be inclined upward so as to approach the opening 52 of the degassing port 50, The bubbles floating along the filter 78 are guided to the degassing port 50, and the air is efficiently discharged from the degassing port 50 to the outside. Therefore, it is difficult for the air to remain in the pre-degassing liquid chamber 80 after the priming process, and the removal of the air in the circulating liquid can be effectively realized.
 特に、気泡を含み得る脱気前液室80内の循環液が斜めに配されたフィルタ78の下面に接するようにされていることから、フィルタ78によって循環液から濾しとられた気泡は、浮力によりフィルタ78に沿って浮上する。それ故、気泡を安定して脱気ポート50へ導くことが可能となる。 In particular, since the circulating liquid in the pre-degassing liquid chamber 80, which may contain bubbles, comes into contact with the lower surface of the obliquely arranged filter 78, the bubbles removed from the circulating liquid by the filter 78 are buoyant. Thus, it floats along the filter 78. Therefore, it is possible to stably guide the bubbles to the degassing port 50.
 さらに、フィルタ78が平坦な形状とされていることにより、気泡がフィルタ78の面に対して平行となる方向へ効率的に案内されて、脱気ポート50へ導かれる。しかも、フィルタ78が斜めに配されていることによって、平坦な形状であってもフィルタ78の面積を大きく確保することも可能とされており、フィルタ78を通過する循環液の流量を大きく得ることができる。 Further, since the filter 78 has a flat shape, the bubbles are efficiently guided in the direction parallel to the surface of the filter 78 and guided to the degassing port 50. Moreover, since the filter 78 is arranged obliquely, it is possible to secure a large area of the filter 78 even if the filter 78 has a flat shape, and it is possible to obtain a large flow rate of the circulating liquid passing through the filter 78. You can
 また、フィルタ78がハウジング12の第1の液室壁部材44にインサート成形で直接固着されていることから、フィルタ78が別部材を介して第1の液室壁部材44に間接的に取り付けられる場合に比して、第1の液室壁部材44の壁内面におけるフィルタ78の取付部分に段差や凹凸などが形成され難くなっている。それ故、プライミング処理の完了後に空気が残留し難く、空気の効率的な排出が実現される。加えて、第2の液室壁部材46の壁内面におけるフィルタ78の取付部分にも段差や凹凸などが形成され難く、プライミング処理の完了後に空気の残留が防止される。 Further, since the filter 78 is directly fixed to the first liquid chamber wall member 44 of the housing 12 by insert molding, the filter 78 is indirectly attached to the first liquid chamber wall member 44 via another member. Compared with the case, it is more difficult to form a step or unevenness in the mounting portion of the filter 78 on the inner surface of the wall of the first liquid chamber wall member 44. Therefore, it is difficult for the air to remain after the completion of the priming process, and the efficient discharge of the air is realized. In addition, steps or irregularities are unlikely to be formed in the mounting portion of the filter 78 on the inner wall surface of the second liquid chamber wall member 46, and air is prevented from remaining after the priming process is completed.
 循環液を循環液入口ポート30から導入するに際して、循環液入口ポート30から底部材18の内周へ流入した循環液は、底部材18の周壁に設けられた分流突起40に向かって溝部36を流れる。そして、循環液の流れは、分流突起40に当たることで周方向両側へ分けられる。本実施形態では、分流突起40が循環液入口ポート30側である先端側に向けて幅狭となっていることから、循環液の流れが分流突起40によって周方向両側へ効率的に分けられる。これにより、循環液入口ポート30から底部材18の内側へ流れ込んだ循環液の流れが、流れと略直交する底部材18の周壁によって堰き止められることなく、周方向の両側へスムーズに案内される。それ故、乱流による気泡の巻き込みなどが生じ難く、底部材18の内側を循環液で速やかに満たすことができる。 When the circulating liquid is introduced from the circulating liquid inlet port 30, the circulating liquid flowing from the circulating liquid inlet port 30 into the inner periphery of the bottom member 18 is guided to the groove portion 36 toward the flow dividing projection 40 provided on the peripheral wall of the bottom member 18. Flowing. Then, the flow of the circulating liquid hits the flow dividing projection 40 to be divided into both sides in the circumferential direction. In the present embodiment, since the flow dividing projection 40 is narrowed toward the tip side which is the circulating liquid inlet port 30 side, the flow of the circulating liquid is efficiently divided into both sides in the circumferential direction by the flow dividing projection 40. Accordingly, the flow of the circulating liquid flowing from the circulating liquid inlet port 30 to the inside of the bottom member 18 is smoothly guided to both sides in the circumferential direction without being blocked by the peripheral wall of the bottom member 18 which is substantially orthogonal to the flow. .. Therefore, entrainment of bubbles due to turbulent flow is unlikely to occur, and the inside of the bottom member 18 can be quickly filled with the circulating liquid.
 さらに、分流突起40に対する底部材18の周方向両側には、分流突起40から循環液入口ポート30に向けて周方向に延びるガイド突条42,42が設けられている。これにより、分流突起40によって周方向の両側に分けられた循環液の流れが、ガイド突条42,42によって底部材18の外周部分を周方向に案内される。その結果、分流突起40によって方向を変えられた循環液の流れが、循環液入口ポート30から流れ込んで底部材18の中央を通る径方向に流れる循環液の流れと衝突し難く、流れのぶつかり合いによる乱流が生じ難い。 Further, guide ridges 42, 42 extending in the circumferential direction from the flow dividing projection 40 toward the circulating liquid inlet port 30 are provided on both sides in the circumferential direction of the bottom member 18 with respect to the flow dividing projection 40. As a result, the flow of the circulating liquid divided into both sides in the circumferential direction by the flow dividing projection 40 is guided in the circumferential direction on the outer peripheral portion of the bottom member 18 by the guide projections 42, 42. As a result, the flow of the circulating liquid whose direction has been changed by the flow dividing projections 40 hardly collides with the flow of the circulating liquid flowing from the circulating liquid inlet port 30 and passing through the center of the bottom member 18, and thus the flow collides. Turbulent flow due to
 循環液入口ポート30は、溝部36の端面に開口しており、底上部38,38の上面よりも下側に位置している。それ故、循環液入口ポート30から流入する循環液の流れと、ガイド突条42,42に案内されて底上部38,38上を流れる循環液の流れは、上下方向においても互いにずれた位置に形成されており、互いにぶつかり合い難くなっている。 The circulating fluid inlet port 30 is open at the end surface of the groove 36, and is located below the upper surfaces of the bottom upper portions 38, 38. Therefore, the flow of the circulating liquid flowing in from the circulating liquid inlet port 30 and the flow of the circulating liquid flowing on the bottom upper portions 38, 38 guided by the guide protrusions 42, 42 are displaced from each other even in the vertical direction. They are formed and are hard to bump into each other.
 ガイド突条42,42が設けられた外周部分は、溝部36よりも深さが浅い底上部38,38とされていることから、分流突起40によって分けられた循環液の流れが、伝熱管68の端部開口に近い位置を流動する。それ故、底部材18の内側へ導入された循環液が伝熱管68の内腔へ導かれ易く、循環液の熱交換部14への導入も効率的に実現され得る。しかも、底上部38は、分流突起40側から循環液入口ポート30側に向けて次第に上傾して伝熱管68の端部開口に接近している。それ故、循環液入口ポート30側においても、底上部38上を流れる循環液が、伝熱管68の内腔へ有効に導入される。 Since the outer peripheral portions where the guide ridges 42, 42 are provided are the bottom upper portions 38, 38 having a shallower depth than the groove portion 36, the flow of the circulating liquid divided by the flow dividing protrusions 40 is applied to the heat transfer pipe 68. Flow near the end opening. Therefore, the circulating liquid introduced into the bottom member 18 is easily guided to the inner cavity of the heat transfer tube 68, and the circulating liquid can be efficiently introduced into the heat exchange section 14. Moreover, the bottom upper portion 38 gradually inclines from the side of the flow dividing projection 40 toward the side of the circulating liquid inlet port 30 and approaches the end opening of the heat transfer tube 68. Therefore, also on the circulating liquid inlet port 30 side, the circulating liquid flowing on the bottom upper portion 38 is effectively introduced into the inner cavity of the heat transfer tube 68.
 ところで、プライミング処理が完了した後、熱交換器10によって循環液の温度調節が行われて、温度調節された循環液が体外循環回路へ供給される。すなわち、熱交換媒体入口ポート24へ送入された熱交換媒体は、複数の伝熱管68の間に設けられた隙間を通じて熱交換媒体出口ポート26から排出される。そして、循環液入口ポート30から熱交換器10に入った循環液は、伝熱管68の内腔を通る際に熱交換媒体と間接的に接して、循環液と熱交換媒体の間で伝熱管68を介した熱の交換(授受)が生じる。これにより、循環液の温度が調節されて、熱交換部14において調温された循環液が、調温後液室76(脱気前液室80)へ流入するようになっている。なお、熱交換器10を通過した循環液の温度は、特に限定されないが、冷却と加温の両方に対応可能とされていることが望ましい。例えば、心停止状態で使用される循環液を冷却することにより、心停止下において心筋が保護されると共に、心停止の解除に際して生体温度まで加温した循環液を患者に供給することで、患者の心臓の代謝機能を正常な状態に戻すことができる。冷却と加温の両方に対応可能とする場合には、冷却時の循環液と加温時の循環液は、互いに同じであってもよいし、互いに異なっていてもよい。 By the way, after the priming process is completed, the temperature of the circulating fluid is adjusted by the heat exchanger 10, and the temperature-controlled circulating fluid is supplied to the extracorporeal circulation circuit. That is, the heat exchange medium introduced into the heat exchange medium inlet port 24 is discharged from the heat exchange medium outlet port 26 through the gap provided between the plurality of heat transfer tubes 68. The circulating liquid that has entered the heat exchanger 10 from the circulating liquid inlet port 30 is indirectly contacted with the heat exchange medium when passing through the inner cavity of the heat transfer pipe 68, and the heat transfer pipe is provided between the circulating liquid and the heat exchange medium. Heat exchange (transfer) via 68 occurs. As a result, the temperature of the circulating liquid is adjusted, and the circulating liquid whose temperature has been adjusted in the heat exchange section 14 flows into the temperature-adjusted liquid chamber 76 (pre-degassing liquid chamber 80). The temperature of the circulating liquid that has passed through the heat exchanger 10 is not particularly limited, but it is desirable that it be compatible with both cooling and heating. For example, by cooling the circulating fluid used in the cardiac arrest state, the myocardium is protected under cardiac arrest, and at the time of releasing cardiac arrest, the circulating fluid heated to the living body temperature is supplied to the patient, Can restore the normal metabolic function of the heart. When both cooling and heating are possible, the circulating liquid during cooling and the circulating liquid during heating may be the same as each other or may be different from each other.
 熱交換媒体は、収容筒部22の内周側の空間に対して、下部から導入されて、下部から排出されることから、収容筒部22の上部には流れにくい。そこで、収容筒部22の内周面が上方に向けて小径となるテーパ形状とされており、収容筒部22の内周面と複数の伝熱管68からなる管群の外周面との対向面間距離が上方に向けて次第に小さくされている。これにより、収容筒部22の下部から送入された熱交換媒体が、圧力損失による流速の低下を抑えられて、収容筒部22の上部まで流動し易くなる。それ故、熱交換媒体入口ポート24から流れ込む熱交換媒体が、熱交換部14の全体に供給されて、循環液と熱交換媒体との間での熱交換効率の向上が図られる。 The heat exchange medium is introduced into the space on the inner peripheral side of the housing tubular portion 22 from the lower portion and discharged from the lower portion, so that the heat exchange medium does not easily flow to the upper portion of the housing tubular portion 22. Therefore, the inner peripheral surface of the accommodating cylinder portion 22 is formed into a taper shape having a smaller diameter toward the upper side, and the opposing surface between the inner peripheral surface of the accommodating cylinder portion 22 and the outer peripheral surface of the tube group including the plurality of heat transfer tubes 68. The distance is gradually decreasing upward. As a result, the heat exchange medium fed from the lower portion of the accommodating cylinder portion 22 is suppressed from decreasing in the flow velocity due to pressure loss, and easily flows to the upper portion of the accommodating cylinder portion 22. Therefore, the heat exchange medium flowing in from the heat exchange medium inlet port 24 is supplied to the entire heat exchange section 14, and the heat exchange efficiency between the circulating liquid and the heat exchange medium is improved.
 本実施形態では、循環液入口ポート30から熱交換部14へ導入された循環液が伝熱管68の内腔を通じて流動すると共に、熱交換媒体が複数の伝熱管68の外周面間を流動するようにされている。これにより、熱交換部14において、循環液の流動領域(伝熱管68の内腔)の容積が、熱交換媒体の流動領域(複数の伝熱管68の隙間)の容積よりも小さくされている。それ故、プライミング完了時に熱交換部14に残るプライミング液の量が少なくなって、体外循環回路から患者の体内(血管)へ入る当該プライミング液による血液の希釈を抑えることができる。 In the present embodiment, the circulating liquid introduced from the circulating liquid inlet port 30 to the heat exchange section 14 flows through the lumen of the heat transfer tube 68, and the heat exchange medium flows between the outer peripheral surfaces of the plurality of heat transfer tubes 68. Has been As a result, in the heat exchange section 14, the volume of the circulation region of the circulating liquid (the inner cavity of the heat transfer pipe 68) is made smaller than the volume of the flow region of the heat exchange medium (the gap between the plurality of heat transfer pipes 68). Therefore, the amount of the priming liquid remaining in the heat exchange unit 14 at the time of completion of the priming is reduced, and it is possible to suppress the dilution of blood by the priming liquid entering the body (blood vessel) of the patient from the extracorporeal circulation circuit.
 さらに、薬液投与ポート32に図示しないシリンジやチューブを接続して、薬液投与ポート32から循環液に薬液を適宜に投与することもできる。なお、図7では、薬液投与ポート32にキャップ34が取り付けられているが、薬液投与時にキャップ34を取り外してもよいし、予めキャップを取り外して図示しないチューブを接続しておいて、当該チューブをクランプすることで薬液投与ポート32を遮断状態としてもよい。 Further, by connecting a syringe or a tube (not shown) to the drug solution administration port 32, the drug solution can be appropriately administered from the drug solution administration port 32 to the circulating fluid. In FIG. 7, the cap 34 is attached to the drug solution administration port 32, but the cap 34 may be removed at the time of drug solution administration, or the cap may be previously removed and a tube (not shown) may be connected, and the tube may be removed. The drug solution administration port 32 may be blocked by clamping.
 このような熱交換器10のプライミング完了後の使用状態においても、循環液中に混じった空気は、フィルタ78によって取り除かれて、脱気ポート50へ集められる。脱気ポート50は、プライミング完了後に遮断されており、循環液の脱気ポート50からの漏れが防止されるが、脱気ポート50に空気が集まっている状態は、脱気ポート50を含む第1の液室壁部材44が透明であることから、外部から目視で確認可能とされている。それ故、脱気ポート50に空気が集まったことを確認した場合には、脱気ポート50を一時的に開放することで空気を外部に排出することができる。なお、プライミング処理の完了後に脱気ポート50に接続されたチューブをクランプすることによって脱気ポート50が遮断されることから、熱交換器10の使用状態で空気を排出する際には、チューブのクランプを一時的に解除すればよい。 The air mixed in the circulating fluid is removed by the filter 78 and collected in the degassing port 50 even in the use state after the priming of the heat exchanger 10 is completed. The deaeration port 50 is shut off after the priming is completed, and leakage of the circulating fluid from the deaeration port 50 is prevented. However, the state where the air is collected in the deaeration port 50 includes the deaeration port 50. Since the first liquid chamber wall member 44 is transparent, it can be visually confirmed from the outside. Therefore, when it is confirmed that the air has collected in the deaeration port 50, the air can be discharged to the outside by temporarily opening the deaeration port 50. Since the deaeration port 50 is blocked by clamping the tube connected to the deaeration port 50 after the completion of the priming process, when the air is exhausted while the heat exchanger 10 is in use, You can temporarily release the clamp.
 なお、温度検出ポート60は、フィルタ78によって空気を除去された循環液で満たされる脱気後液室82の壁部に設けられており、温度検出部材62が温度検出ポート60から脱気後液室82内へ突出するように設けられても、気泡が温度検出部材62に付着して液室内に残留することはない。 The temperature detection port 60 is provided on the wall portion of the post-degassing liquid chamber 82 filled with the circulating liquid from which air has been removed by the filter 78, and the temperature detection member 62 is used to remove the post-degassing liquid from the temperature detection port 60. Even if the bubbles are provided so as to project into the chamber 82, the bubbles do not adhere to the temperature detecting member 62 and remain in the liquid chamber.
 以上、本発明の実施形態について詳述してきたが、本発明はその具体的な記載によって限定されない。例えば、前記実施形態では、熱交換部14における循環液の流動方向と熱交換媒体の流動方向が交差方向とされていたが、循環液と熱交換媒体の両方が上下方向に流動するようにしてもよく、その場合には、循環液の流動方向と熱交換媒体の流動方向は、相互に同じ方向であってもよいし、逆方向であってもよい。 Although the embodiments of the present invention have been described in detail above, the present invention is not limited by the specific description thereof. For example, in the above-described embodiment, the flowing direction of the circulating liquid and the flowing direction of the heat exchanging medium in the heat exchanging section 14 are set to intersect with each other, but both the circulating liquid and the heat exchanging medium flow vertically. In that case, the flowing direction of the circulating liquid may be the same as the flowing direction of the heat exchange medium, or may be the opposite direction.
 また、フィルタ78は、平坦な形状に限定されるものではなく、例えば上方に向けて小径となるテーパ状の筒形などであってもよい。この場合、フィルタ78は、上端が脱気ポート50の開口52の周囲を囲んで配置されることにより、フィルタ78に沿って上方へ移動する気泡が脱気ポート50へ案内される。さらに、フィルタ78は、湾曲板状や波板状、折れ板状などであってもよい。また、フィルタ78をハウジング本体16に固定する方法は、インサート成形に限定されない。具体的には、フィルタ78をハウジング本体16とは別部品として、ハウジング本体16に接着する方法が挙げられる。 Further, the filter 78 is not limited to a flat shape, and may be, for example, a tapered cylindrical shape whose diameter decreases upward. In this case, the upper end of the filter 78 is arranged so as to surround the opening 52 of the degassing port 50, so that bubbles moving upward along the filter 78 are guided to the degassing port 50. Further, the filter 78 may have a curved plate shape, a corrugated plate shape, a bent plate shape, or the like. Further, the method of fixing the filter 78 to the housing body 16 is not limited to insert molding. Specifically, a method of adhering the filter 78 to the housing body 16 as a separate component from the housing body 16 can be mentioned.
 また、ハウジング12は、全体が透明である必要はなく、例えば、ハウジング12の上側の壁部を構成する蓋部材20だけが透明とされていてもよいし、蓋部材20に設けられた脱気ポート50だけが透明とされていてもよい。なお、気泡の有無を外部から確認するために、少なくとも脱気ポート50の根元部分が透明乃至は半透明であることが望ましく、より好適には、脱気ポート50と脱気前液室80の壁部とを構成する第1の液室壁部材44が透明乃至は半透明とされるが、ハウジング12の全体を不透明な材料で形成することも可能である。 Further, the entire housing 12 does not need to be transparent, and for example, only the lid member 20 forming the upper wall portion of the housing 12 may be transparent, or the degassing provided on the lid member 20 may be performed. Only the port 50 may be transparent. In order to confirm the presence or absence of air bubbles from the outside, it is desirable that at least the root portion of the degassing port 50 is transparent or translucent, and more preferably, the degassing port 50 and the pre-degassing liquid chamber 80. Although the first liquid chamber wall member 44 forming the wall portion is transparent or translucent, the entire housing 12 can be formed of an opaque material.
 熱交換器10は、患者への身体的な負担を低減する目的で、患者の血液を循環液の流路に導入する場合がある。この場合には、血液を循環液の流路に導入するための外部管路に接続されるサービスポートが、ハウジング12に設けられ得る。サービスポートは、外部管路との接続によって空気が混入することを考慮して、フィルタ78を通過する前の循環液に血液を混入可能な位置に設けられる。具体的には、サービスポートは、底部材18や蓋部材20の第1の液室壁部材44に設けることが可能であり、例えば、前記実施形態の圧力検出ポート56をサービスポートとして用いることもできる。なお、循環液の流路に導入される血液を貯留する貯血槽は、例えば、ハウジング12に設けられた取付突部28a,28bによって収容筒部22の外周面に取り付けられ得る。 The heat exchanger 10 may introduce the patient's blood into the circulating fluid passage in order to reduce the physical burden on the patient. In this case, the housing 12 may be provided with a service port connected to an external conduit for introducing blood into the flow path of the circulating fluid. The service port is provided at a position where blood can be mixed into the circulating fluid before passing through the filter 78, considering that air is mixed due to the connection with the external pipeline. Specifically, the service port can be provided in the first liquid chamber wall member 44 of the bottom member 18 or the lid member 20, and for example, the pressure detection port 56 of the above-described embodiment can be used as the service port. it can. The blood reservoir that stores the blood introduced into the flow path of the circulating fluid can be attached to the outer peripheral surface of the housing cylinder portion 22 by the attachment protrusions 28 a and 28 b provided on the housing 12, for example.
10:熱交換器、12:ハウジング、14:熱交換部、18:底部材、40:分流突起、42:ガイド突条、44:第1の液室壁部材、46:第2の液室壁部材、50:脱気ポート、52:開口、60:温度検出ポート、76:調温後液室、78:フィルタ、80:脱気前液室、82:脱気後液室 DESCRIPTION OF SYMBOLS 10: Heat exchanger, 12: Housing, 14: Heat exchange part, 18: Bottom member, 40: Flow protrusion, 42: Guide ridge, 44: 1st liquid chamber wall member, 46: 2nd liquid chamber wall Member, 50: Degassing port, 52: Opening, 60: Temperature detection port, 76: Liquid chamber after temperature adjustment, 78: Filter, 80: Liquid chamber before degassing, 82: Liquid chamber after degassing

Claims (11)

  1.  循環液の温度を調節する熱交換部を備えた熱交換器であって、
     前記熱交換部において温度調節された前記循環液が流入する調温後液室が設けられていると共に、該調温後液室には該循環液中の空気を除去するフィルタが配されて、該調温後液室の壁部には脱気ポートが設けられており、該フィルタが該脱気ポートへ向けて傾斜して設けられていることを特徴とする熱交換器。
    A heat exchanger having a heat exchange section for adjusting the temperature of the circulating fluid,
    A temperature-adjusted liquid chamber into which the temperature-controlled circulating liquid flows in is provided in the heat exchange section, and a filter for removing air in the circulating liquid is arranged in the temperature-controlled liquid chamber, A heat exchanger characterized in that a deaeration port is provided on a wall portion of the temperature-adjusted liquid chamber, and the filter is provided so as to be inclined toward the deaeration port.
  2.  前記調温後液室は前記フィルタの両側が脱気前液室と脱気後液室とされており、前記脱気ポートが該脱気前液室の壁部に設けられている請求項1に記載の熱交換器。 The pre-degassing liquid chamber and the post-degassing liquid chamber are provided on both sides of the filter in the post-temperature regulating liquid chamber, and the degassing port is provided in a wall portion of the pre-degassing liquid chamber. The heat exchanger described in.
  3.  前記フィルタが、前記調温後液室の壁部を構成するハウジングにインサート成形されたインサート構成部材とされている請求項1又は2に記載の熱交換器。 The heat exchanger according to claim 1 or 2, wherein the filter is an insert component member that is insert-molded in a housing that forms a wall portion of the temperature-adjusted liquid chamber.
  4.  前記調温後液室内の温度を測定するための温度検出ポートが、前記調温後液室の壁部に設けられている請求項1~3の何れか1項に記載の熱交換器。 The heat exchanger according to any one of claims 1 to 3, wherein a temperature detection port for measuring the temperature in the temperature-adjusted liquid chamber is provided on the wall of the temperature-controlled liquid chamber.
  5.  前記脱気ポートの少なくとも根元部分が透明とされている請求項1~4の何れか1項に記載の熱交換器。 The heat exchanger according to any one of claims 1 to 4, wherein at least a root portion of the degassing port is transparent.
  6.  前記フィルタが平坦な形状とされている請求項1~5の何れか1項に記載の熱交換器。 The heat exchanger according to any one of claims 1 to 5, wherein the filter has a flat shape.
  7.  前記フィルタが疎水性材料で形成されている請求項1~6の何れか1項に記載の熱交換器。 The heat exchanger according to any one of claims 1 to 6, wherein the filter is made of a hydrophobic material.
  8.  前記フィルタが親水性材料で形成されている請求項1~6の何れか1項に記載の熱交換器。 The heat exchanger according to any one of claims 1 to 6, wherein the filter is made of a hydrophilic material.
  9.  循環液の温度を調節する熱交換部を備えた熱交換器であって、
     前記熱交換部において温度調節された前記循環液が流入する調温後液室が設けられていると共に、該調温後液室には該循環液中の空気を除去するフィルタが配されて、該調温後液室における該フィルタの両側が脱気前液室と脱気後液室とされていると共に、該フィルタが該調温後液室の壁部を構成するハウジングにインサート成形されたインサート構成部材とされていることを特徴とする熱交換器。
    A heat exchanger having a heat exchange section for adjusting the temperature of the circulating fluid,
    A temperature-adjusted liquid chamber into which the temperature-controlled circulating liquid flows in is provided in the heat exchange section, and a filter for removing air in the circulating liquid is arranged in the temperature-controlled liquid chamber, Both sides of the filter in the temperature controlled liquid chamber are a pre-degassed liquid chamber and a post-degassed liquid chamber, and the filter is insert-molded in a housing forming a wall portion of the temperature controlled liquid chamber. A heat exchanger characterized by being an insert component.
  10.  前記ハウジングが前記脱気前液室の壁部を構成する第1の液室壁部材と前記脱気後液室の壁部を構成する第2の液室壁部材とを備えており、前記フィルタが該ハウジングの該第1の液室壁部材に取り付けられている請求項9に記載の熱交換器。 The housing includes a first liquid chamber wall member that forms a wall portion of the pre-degassing liquid chamber, and a second liquid chamber wall member that forms a wall portion of the post-degassing liquid chamber, and the filter The heat exchanger according to claim 9, wherein is attached to the first liquid chamber wall member of the housing.
  11.  前記熱交換部に連通されて前記循環液を該熱交換部へ導入する循環液入口ポートを備えた底部材が設けられており、
     該底部材における該循環液入口ポートの開口と対向する部分には、該循環液入口ポートに向けて突出する分流突起が設けられていると共に、
     該分流突起に対する該底部材の周方向の両側には、該底部材の周方向に延びるガイド突条が設けられている請求項1~10の何れか1項に記載の熱交換器。
    A bottom member is provided which is in communication with the heat exchange section and which has a circulating fluid inlet port for introducing the circulating fluid into the heat exchange section,
    At a portion of the bottom member facing the opening of the circulating liquid inlet port, a flow dividing projection protruding toward the circulating liquid inlet port is provided, and
    11. The heat exchanger according to claim 1, wherein guide ridges extending in the circumferential direction of the bottom member are provided on both sides of the bottom member in the circumferential direction with respect to the flow dividing projections.
PCT/JP2019/043552 2018-11-12 2019-11-06 Heat exchanger WO2020100693A1 (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000025843A1 (en) * 1998-11-02 2000-05-11 Lifestream International, Inc. Cardioplegia heat exchanger
JP2010200884A (en) * 2009-03-02 2010-09-16 Jms Co Ltd Artificial lung device
WO2011099610A1 (en) * 2010-02-15 2011-08-18 ニプロ株式会社 Heat exchanger and heat exchanger-integrated artificial lung
WO2012132110A1 (en) * 2011-03-31 2012-10-04 テルモ株式会社 Artificial lung and extracorporeal circulation device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000025843A1 (en) * 1998-11-02 2000-05-11 Lifestream International, Inc. Cardioplegia heat exchanger
JP2010200884A (en) * 2009-03-02 2010-09-16 Jms Co Ltd Artificial lung device
WO2011099610A1 (en) * 2010-02-15 2011-08-18 ニプロ株式会社 Heat exchanger and heat exchanger-integrated artificial lung
WO2012132110A1 (en) * 2011-03-31 2012-10-04 テルモ株式会社 Artificial lung and extracorporeal circulation device

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