WO2020099921A3 - Methods and systems for generating composite neurostimulation - Google Patents

Methods and systems for generating composite neurostimulation Download PDF

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Publication number
WO2020099921A3
WO2020099921A3 PCT/IB2019/001173 IB2019001173W WO2020099921A3 WO 2020099921 A3 WO2020099921 A3 WO 2020099921A3 IB 2019001173 W IB2019001173 W IB 2019001173W WO 2020099921 A3 WO2020099921 A3 WO 2020099921A3
Authority
WO
WIPO (PCT)
Prior art keywords
parameters
component
burst stimulation
stimulation component
composite
Prior art date
Application number
PCT/IB2019/001173
Other languages
French (fr)
Other versions
WO2020099921A2 (en
Inventor
Dirk De Ridder
Original Assignee
Dirk De Ridder
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dirk De Ridder filed Critical Dirk De Ridder
Publication of WO2020099921A2 publication Critical patent/WO2020099921A2/en
Publication of WO2020099921A3 publication Critical patent/WO2020099921A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36178—Burst or pulse train parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36182—Direction of the electrical field, e.g. with sleeve around stimulating electrode
    • A61N1/36185—Selection of the electrode configuration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

A method and system of treating a neurological disorder in a patient re provided. The method obtains a burst stimulation component that has a select effect on a neurological condition of a patient and identifies a noise structure (NS) and NS filtering parameters to apply the noise structure to the burst stimulation component. The method determines synchrony reset (SR) parameters related to applying the burst stimulation component in at least one of a coordinated or uncoordinated manner and nesting parameters defining cross frequency coupling between the burst stimulation component and an infra slow carrier component. The method builds a composite stimulation waveform structure (SWS) by i) combining the burst stimulation component and noise structure based on the NS filtering parameters and ii) based on the at least one of SR parameters and nesting parameters and applies electrical stimulation having the composite SWS to one or more neurological sites.
PCT/IB2019/001173 2018-11-12 2019-11-06 Methods and systems for generating composite neurostimulation WO2020099921A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862758776P 2018-11-12 2018-11-12
US62/758,776 2018-11-12

Publications (2)

Publication Number Publication Date
WO2020099921A2 WO2020099921A2 (en) 2020-05-22
WO2020099921A3 true WO2020099921A3 (en) 2020-06-25

Family

ID=69187813

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2019/001173 WO2020099921A2 (en) 2018-11-12 2019-11-06 Methods and systems for generating composite neurostimulation

Country Status (1)

Country Link
WO (1) WO2020099921A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220080202A1 (en) * 2020-09-11 2022-03-17 Advanced Neuromodulation Systems, Inc. Systems and methods for generating pulsed waveforms that approximate colored noise
TWI826150B (en) * 2022-01-12 2023-12-11 塞席爾商凡尼塔斯研究中心股份有限公司 PROGRAMMABLE rTMS APPARATUS, rTMS APPARATUS AND PROGRAMMABLE SYSTEM, ELECTRIC STIMULATION APPARATUS

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120059438A1 (en) * 2010-08-30 2012-03-08 Dirk De Ridder Use of a new stimulation design to treat neurological disorder
US20150343215A1 (en) * 2014-06-03 2015-12-03 Dirk De Ridder Systems and methods of treating a neurological disorder in a patient
US20160367812A1 (en) * 2015-03-24 2016-12-22 Dirk De Ridder Methods of neuromodulation
US20170001016A1 (en) * 2015-07-02 2017-01-05 Dirk De Ridder Methods of sensing cross-frequency coupling and neuromodulation
US20170333715A1 (en) * 2014-09-11 2017-11-23 Dirk De Ridder Methods of neuromodulation using infraslow stimulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5938690A (en) 1996-06-07 1999-08-17 Advanced Neuromodulation Systems, Inc. Pain management system and method
US6748276B1 (en) 2000-06-05 2004-06-08 Advanced Neuromodulation Systems, Inc. Neuromodulation therapy system
US7228179B2 (en) 2002-07-26 2007-06-05 Advanced Neuromodulation Systems, Inc. Method and apparatus for providing complex tissue stimulation patterns
US7571007B2 (en) 2004-04-12 2009-08-04 Advanced Neuromodulation Systems, Inc. Systems and methods for use in pulse generation
US7212110B1 (en) 2004-04-19 2007-05-01 Advanced Neuromodulation Systems, Inc. Implantable device and system and method for wireless communication
US8239029B2 (en) 2004-10-21 2012-08-07 Advanced Neuromodulation Systems, Inc. Stimulation of the amygdalohippocampal complex to treat neurological conditions
EP2243512A3 (en) 2005-01-31 2016-01-20 Advanced Neuromodulation Systems, Inc. Pulse generator having an efficient fractional voltage converter and method of use
WO2009158495A1 (en) 2008-06-25 2009-12-30 Advanced Neuromodulation Systems, Inc. Method of electrically stimulating tissue of a patient by shifting a locus of stimulation and system employing the same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120059438A1 (en) * 2010-08-30 2012-03-08 Dirk De Ridder Use of a new stimulation design to treat neurological disorder
US20150343215A1 (en) * 2014-06-03 2015-12-03 Dirk De Ridder Systems and methods of treating a neurological disorder in a patient
US20170333715A1 (en) * 2014-09-11 2017-11-23 Dirk De Ridder Methods of neuromodulation using infraslow stimulation
US20160367812A1 (en) * 2015-03-24 2016-12-22 Dirk De Ridder Methods of neuromodulation
US20170001016A1 (en) * 2015-07-02 2017-01-05 Dirk De Ridder Methods of sensing cross-frequency coupling and neuromodulation

Also Published As

Publication number Publication date
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