WO2020093608A1 - Shielding apparatus for proton therapy system - Google Patents

Shielding apparatus for proton therapy system Download PDF

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Publication number
WO2020093608A1
WO2020093608A1 PCT/CN2019/073198 CN2019073198W WO2020093608A1 WO 2020093608 A1 WO2020093608 A1 WO 2020093608A1 CN 2019073198 W CN2019073198 W CN 2019073198W WO 2020093608 A1 WO2020093608 A1 WO 2020093608A1
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Prior art keywords
chamber
wall
room
shielding
thickness
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PCT/CN2019/073198
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French (fr)
Chinese (zh)
Inventor
汪金龙
郑志鸿
刘铮铮
李凯若
Original Assignee
新瑞阳光粒子医疗装备(无锡)有限公司
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Priority claimed from CN201811317523.3A external-priority patent/CN109200491A/en
Application filed by 新瑞阳光粒子医疗装备(无锡)有限公司 filed Critical 新瑞阳光粒子医疗装备(无锡)有限公司
Publication of WO2020093608A1 publication Critical patent/WO2020093608A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy

Definitions

  • the present disclosure relates to the technical field of radiation protection, for example, to a shield used in a proton therapy system.
  • Proton therapy is recognized worldwide as the most effective tumor treatment method with the least side effects, and having a 360-degree rotating gantry allows the proton beam to accurately bombard the patient from multiple angles according to the optimal path without moving the patient
  • the location of the tumor is less time-consuming and less harmful to healthy tissues, while enabling proton therapy technology to be applied to more types of tumor treatment.
  • the builder of the proton therapy system should minimize the radiation generated by the proton therapy system to reduce the impact on the public and the environment.
  • the proton therapy system with a rotating gantry in the related art is usually installed in a large building made of concrete; however, the radiation shield of this proton therapy system cannot be conformally designed according to the radiation dose of the therapy system, but is over
  • the shield body is as large and thick as possible to reduce radiation, so that the shield body occupies a large space and the construction cost is high.
  • the type and thickness of the shielding material determine the cost.
  • the present disclosure provides a shielding body for a proton therapy system, which can perform targeted shielding against the radiation of the proton therapy system to achieve the best protection, while saving costs and reducing space occupation.
  • a shielding body for a proton therapy system wherein the shielding body is a multi-chamber structure constructed by a shielding wall, the shielding body includes a synchrotron chamber and a rotating gantry chamber, the synchrotron chamber and the rotation
  • the rack rooms communicate with each other;
  • the rotating rack room includes an upper rotating rack room, a lower rotating rack room, and a rack slot opened between the upper rotating rack room and the lower rotating rack room.
  • the upper rotating frame chamber is located at an upper part of the lower rotating frame chamber, and the upper rotating frame chamber is arranged to communicate with the synchrotron chamber and form a cavity.
  • Example 1 is a schematic structural diagram of a proton therapy system provided in Example 1;
  • FIG. 2 is a schematic structural view of each chamber of the shielding body provided in Embodiment 2 cut away;
  • Embodiment 3 is a dose distribution diagram of the intermediate cross-section of the shielding body provided in Embodiment 2;
  • FIG. 4 is a dose distribution diagram on the middle longitudinal section of the shielding body provided in Embodiment 2;
  • FIG. 5 is a schematic structural view of each chamber of the shielding body provided in Embodiment 3 cut away;
  • FIG. 6 is a dose distribution diagram of the intermediate cross section of the shielding body provided in Embodiment 3.
  • FIG. 8 is a radiation dose distribution diagram of the proton therapy system in the case of setting different shielding walls in the fourth embodiment
  • FIG. 9 is a schematic diagram of the function of scanning the treatment head and the target body in the fourth embodiment.
  • 31 '-synchrotron room 32, 32'-rotating frame room; 321, 321 '-upper rotating frame room; 322, 322'-lower rotating frame room; 323, 323 '-frame slot; 33, 33′-treatment room; 34, 34′-maze room; 35, 35′-equipment room;
  • the proton therapy system 1 is a 360 ° rotating gantry proton therapy system, which includes an injector 11 and a synchrotron 12 connected in sequence.
  • the protons are injected into synchrotron 12 by injector 11 and accelerated by synchrotron 12 to obtain energy to form a proton beam.
  • the proton beam is guided by the magnet of the extraction device 13 to the rotating frame 14 through the three of the rotating frame 14 After a two-pole magnet is emitted from the scanning treatment head 15 to the target body 2 (ie, the lesion of the patient), the treatment is completed.
  • the proton beam will cause a large beam loss on the two-pole magnet of the synchrotron 12, the three-pole magnet of the extraction magnet and the rotating gantry 14, and the scanning treatment head 15, resulting in strong radiation energy, so In the design of radiation shields, it is necessary to focus on the radiation protection in these areas.
  • the shield body 3 is a multi-chamber structure constructed by a shield wall as a whole, including a synchrotron room 31, a rotating gantry room 32, a treatment room 33, a labyrinth room 34 and an equipment room 35.
  • the injector 11, synchrotron 12 and extraction device 13 are arranged in the synchrotron chamber 31
  • the rotating frame 14 is arranged in the rotating frame chamber 32
  • the scanning treatment head 15 and the target body 2 are located in the treatment room 33
  • the equipment room 35 is set to place electrical equipment of the proton therapy system 1.
  • the synchrotron chamber 31 and the rotating gantry chamber 32 communicate with each other, and do not have any shielding structure, forming a whole chamber. This arrangement can save space and also reduce the waste of shielding materials.
  • the rotating frame chamber 32 can be divided into an upper upper rotating frame chamber 321 and a lower lower rotating frame chamber 322, the upper rotating frame chamber 321 and the lower A rack slot 323 is provided between the rotating rack chambers 322, and the rotating rack 14 is disposed through the rack slot 323; the shape and structure of the rack slot 323 are designed according to the structure of the rotating rack 14 to avoid excessive radiation
  • the lower rotating rack chamber 322 penetrates.
  • the upper rotating frame chamber 321 and the synchrotron chamber 31 communicate with each other.
  • the partition wall can be a simple wall structure, which can be made of insulating materials such as wooden boards and plastic boards instead of concrete
  • the manufacturing that is, the separation wall only needs to isolate the treatment room 33 and the rotating gantry room 32.
  • the isolation design of the rotating gantry room 32 and the treatment room 33 can save the manufacturing cost of the shield body and avoid the waste of excessive shielding materials.
  • the labyrinth room 34 is disposed on one side of the upper rotating gantry room 321, and communicates with the treatment room 33, so that the operator can enter the treatment room 33 from the labyrinth to help the patient to perform positioning and treatment.
  • the labyrinth room 34 is provided with a labyrinth entrance and a labyrinth exit.
  • the labyrinth entrance is located outside the labyrinth and communicates with the outside world.
  • the labyrinth exit and the treatment room 33 are interconnected. .
  • the equipment room 35 is provided below the labyrinth room 34 and is located on one side of the lower rotating gantry room 322.
  • the entire proton therapy system 1 electrical equipment is placed in the equipment room 35.
  • the equipment 35 room and the lower rotating gantry room 322 are mutually connected. Connected and set to connect electrical equipment to multiple components of the proton therapy system 1.
  • the rotating gantry chamber 32 and the synchrotron chamber 31 of this embodiment communicate with each other without a shielding wall, and a separating wall (not a shielding wall) is provided between the rotating gantry chamber 32 and the treatment room 33, which reduces the construction of the shielding body 3 Cost; in this embodiment, the shielding body 3 is designed with a conformal structure and thickness, so that the shielding body 3 can achieve the protection purpose with the smallest space, and also saves the construction cost, which is beneficial to commercial promotion; the shielding body of this embodiment 3.
  • the use of concrete and iron materials as shielding materials can further reduce the thickness setting of the shielding body 3 and reduce the space occupied by the shielding body 3.
  • the shielding body 3 as described in the first embodiment, the shielding wall of the shielding body 3 is a concrete layer 4, the height and volume of each chamber are designed according to the structure size of each part of the proton therapy system 1, but this embodiment can
  • the lower limit value of the specific wall thickness dimension of the shield body 3 is provided, and the lower limit value is conformally set according to the maximum radiation amount when the proton therapy system 1 located in the shield body 3 is used.
  • the up or down direction in this embodiment is the Z-axis direction
  • the left or right direction is the Y-axis direction
  • the front or back direction is the X-axis direction for easy understanding.
  • the thickness of the upper wall and the lower wall of the synchrotron chamber 31 are set to 2m, and the thickness of the left wall of the synchrotron chamber 31 is set to 2m, where the thickness of the lower part of the left wall can be thickened to 3m for more safety Shielding effect.
  • the thickness of the lower wall of the upper rotating rack chamber 321 is also set to 2m, the thickness of the upper wall is 3m, the thickness of the right wall is set to 2m, and the right wall of the upper rotating rack chamber 321 is set to isolate the upper rotating rack chamber 321 and the labyrinth chamber 34 ; Among them, the thickness of the part of the right wall near the rear side is set to 3m.
  • the thicknesses of the entire synchrotron chamber 31, the front wall of the upper rotating frame chamber 321, and the rear wall of the upper rotating frame chamber 321 are all set to 3 m.
  • the upper wall of the lower rotating frame chamber 322 is the lower wall of the upper rotating frame chamber 321, and the thickness of the side wall, front wall and rear wall of the lower rotating frame chamber 322 is 2m, and the thickness of the lower wall is 3m.
  • the thickness of the upper wall, the lower wall, the right wall, and the rear wall of the labyrinth chamber 34 are all set to 1 m, and the thickness of the front wall of the labyrinth chamber 34 is set to 2 m.
  • a layer of shielding wall is added on the outer side of the right wall of the upper rotating frame chamber 321, the shielding wall is located above the labyrinth chamber 34, and the thickness is set to 0.5m.
  • the upper wall of the equipment room 35 is the lower wall of the labyrinth room 34.
  • the equipment room 35 and the lower rotating rack room 322 are separated by the right wall of the lower rotating rack room 322, and the front wall, rear wall, and lower wall of the equipment room 35
  • the thickness of the right wall is 0.5m.
  • the requirements of the national standard GB18871-2002 are: occupational exposure annual dose is less than 20 mSv, and public exposure annual dose is less than 1mSv.
  • the design goal of the shielding body 3 provided in this embodiment is that the annual dose of occupational exposure is less than 5mSv, which is 1/4 of the national standard, and the annual dose of public exposure is less than 0.1mSv, which is 1/10 of the national standard, as shown in Table 1:
  • the proton therapy system 1 has a proton extraction capability in the range of 70-230 megaelectron volts (MeV) and a maximum flow intensity of 2nA.
  • the proton therapy system 1 is analyzed according to the maximum flow intensity, and the equivalent dose (unit is mSv) for comparative analysis to obtain the radiation dose distribution diagrams shown in Figures 3-4.
  • Figure 3 is the dose distribution diagram of the shield 3 in the middle cross section.
  • the lower part of Figure 3 is a graphical representation of the dose distribution value.
  • Figure 3 is marked with three standard lines, from left to right are 0.1mSv, 1mSv and 5mSv, In the distribution diagram, correspondingly draw the connection diagram of the above standard lines. It can be seen that each standard line almost falls on the side wall of the shield 3, wherein the outermost curve is the dose line of 0.1mSv, The middle curve is the dose line of 1 mSv, and the innermost curve is the dose line of 5 mSv, which proves that the shielding body 3 can shield the standard of radiating to 0.1 mSv. That is, the shielding body 3 can meet not only the radiation dose limit standard for professional personnel and the public in the national standard, but also the radiation dose limit standard in this embodiment.
  • Fig. 4 is a dose distribution diagram on the middle longitudinal section of the shield 3, and the lower part of Fig. 4 is a graphical representation of the dose distribution values.
  • There are three standard lines marked on Fig. 4, from left to right are 0.1mSv, 1mSv and 5mSv, In the distribution diagram, correspondingly draw the above standard wiring diagram. It can be seen that each standard line almost falls on the side wall of the shield 3, wherein the outermost curve is the dose line of 0.1mSv, the middle The curve is a dose line of 1 mSv, and the innermost curve is a dose line of 5 mSv, which proves that the shielding body 3 can shield the standard of radiating to 0.1 mSv. That is, the shielding body 3 can meet not only the radiation dose limit standard for professional personnel and the public in the national standard, but also the radiation dose limit standard in this embodiment.
  • each wall thickness of the shielding body 3 is designed and selected according to the minimum value. In specific implementation, it can be thickened according to the level of the cost budget and actual needs. This embodiment is limited to providing a proton therapy system. 1 The lower limit of the wall thickness for which the maximum flow intensity is designed.
  • This embodiment is to provide a shield body 3 ', which has basically the same structure as the shield body 3 in the second embodiment, but differs from the shield body 3 in the second embodiment in that the shield body 3' uses a concrete layer 4 and iron
  • the composite shielding wall formed by the material layer 5 constructs the cavity structure.
  • each chamber In the case of a composite shielding wall, the height and volume of each chamber are still designed according to the structural size of each part of the proton therapy system 1. Since iron material is a good shielding material, the composite shielding wall covered with iron material The radiation resistance is stronger, the combination of concrete and iron materials can reduce the thickness of the shielding layer, so the lower limit of the wall thickness of each chamber will change, but the lower limit is still based on the radiation distribution of the proton therapy system 1 Make conformable settings.
  • the composite shielding wall is formed by coating the inner wall of the concrete layer 4 with the iron material layer 5, and according to the radiation dose distribution, not all the concrete layers 4 are covered with the iron material layer 5, only during radiation
  • the iron material layer 5 is coated in the area with a large dose.
  • the wall thickness of the shielding body 3 'mentioned below refers to the overall thickness of the shielding wall unless otherwise specified, that is, if it is only the concrete layer 4, the wall thickness is the thickness of the concrete layer 4; If it is a composite shield wall, the wall thickness is the overall thickness of the concrete layer 4 and the iron material layer 5, and there are corresponding special instructions for the thickness design of the iron material layer.
  • the thickness of the upper and lower walls of the synchrotron chamber 31 ' is set to 2m, and the thickness of the left wall of the synchrotron chamber 31' is set to 2m, wherein the lower part of the left wall is covered with a layer of iron material 5, iron material Layer 5 has a thickness of 30 cm.
  • the iron material layer 5 replaces the 1 m thick concrete layer 4 added here, but the same shielding effect can be achieved, so that the left wall of the synchrotron chamber 31 ′ is 2 m.
  • the lower wall of the synchrotron chamber 31 ' is covered with a rectangular iron material layer 5 having a length of 700 cm, a width of 600 cm and a thickness of 60 cm.
  • the thickness of the upper and lower walls of the upper rotating rack chamber 321 ' are set to 2m, and the thickness of the right wall of the upper rotating rack chamber is set to 2m, which is set to isolate the upper rotating rack chamber 321' and the labyrinth chamber 34 ';
  • the side wall of the upper wall of the rotating frame room 321 ' is covered with a layer of iron material 5 of 100 cm, which can replace the 1 m thick concrete layer 4 added here; the right wall of the upper rotating frame room 321' is close to the rear side
  • the part is covered with a 50 cm layer of iron material 5 to replace the 1 m thick concrete layer 4 originally designed here.
  • the upper wall of the lower rotating frame chamber 322 ' is the lower wall of the upper rotating frame chamber 321', the side wall thickness of the lower rotating frame chamber 322 'is 2m, and the wall thickness of the lower wall is 2m.
  • the side walls of the lower rotating frame chamber 322 ' are covered with a 50cm thick iron material layer 5, and the right side portion of the lower wall of the lower rotating frame chamber 322' is covered with a 60cm thick iron material layer 5, so set
  • the lower wall of the lower rotating frame chamber 322 ' can be effectively reduced by 1 m in thickness.
  • the thicknesses of the front wall and the rear wall of the entire synchrotron chamber 31 'and the upper rotating frame chamber 321' are set to 2m, which is one-third lower than the setting of the wall thickness of 3m in the second embodiment, because The front wall and the rear wall of the synchrotron chamber 31 'and the upper rotating frame chamber 321' are covered with a layer 5 of iron material.
  • the iron material layer 5 is set to 50 cm on the rear wall of the synchrotron chamber 31 'and 20 cm on the front wall of the synchrotron chamber 31'; but the iron material layer 5 is behind the upper rotating frame chamber 321 '
  • the thickness of the wall is increased to 100cm, and it is set to 70cm on the front wall of the upper rotating gantry chamber 321 '.
  • the main reason is that according to the standard dose line in Figure 3, on the front and rear walls of the upper rotating gantry chamber 321' The radiation dose is greater than the dose of the front wall and the rear wall of the synchrotron chamber 31 ', so the thickness of the iron material layer 5 of the upper rotating frame chamber 321' needs to be set thicker.
  • the thickness of the upper wall, the thickness of the lower wall, the thickness of the right wall and the rear wall of the labyrinth chamber 34 ' are all set to 1m, and the thickness of the front wall is set to 2m.
  • a layer of shielding wall is added to the outer wall of the right wall of the upper rotating rack chamber 321', and the shielding wall is located above the labyrinth chamber 34 'with a thickness of 0.5m.
  • the upper wall of the equipment room 35 ' is the lower wall of the labyrinth room 34'.
  • the thickness of the lower and right walls of the equipment room 35 ' is 0.5m.
  • the equipment room 35' and the lower rotating rack room 322 'pass through the lower rotating rack The right wall of chamber 322 'is isolated.
  • the iron material layer 5 is no longer provided for the equipment room 35 'and the labyrinth room 34' in this embodiment.
  • a Monte Carlo algorithm is used to simulate and analyze the radiation distribution of the shield 3 ′ to verify the shield 3 ′ of this embodiment.
  • the design of the structure and thickness can meet the requirements of radiation protection.
  • the maximum flow intensity of the proton therapy system is still used for analysis, and the radiation dose distribution diagram shown in FIGS. 6 to 7 is obtained.
  • Fig. 6 is the dose distribution diagram of the shield 3 'in the middle cross section.
  • the lower part of Fig. 6 is a graphical representation of the dose distribution values.
  • There are three standard lines marked on Fig. 6, from left to right are 0.1mSv, 1mSv and 5mSv .
  • Correspondingly draw the above standard wiring diagram in the distribution diagram you can see that each standard line still almost falls on the side wall of the shield 3 ', where the outermost curve is the dose of 0.1mSv Line, the middle curve is the dose line of 1mSv, and the innermost curve is the dose line of 5mSv, which proves that the shield 3 'can shield the standard of radiation to 0.1mSv, not to mention the standards of 1mSv and 5mSv. That is, the shielding body 3 'can not only meet the radiation dose limit standard for professional personnel and the public in the national standard, but also meet the radiation dose limit standard in this embodiment.
  • Fig. 7 is the dose distribution diagram of the shield 3 'in the middle longitudinal section.
  • the lower part of Fig. 7 is a graph of the dose distribution values.
  • There are three standard lines marked on Fig. 7, from left to right are 0.1mSv, 1mSv and 5mSv , Correspondingly draw the above standard wiring diagram in the distribution diagram. It can be seen that each standard line almost falls on the side wall of the shield 3 ′, where the outermost curve is the dose line of 0.1mSv
  • the middle curve is the dose line of 1mSv
  • the innermost curve is the dose line of 5mSv, which proves that the shield 3 'can shield the standard of radiating to 0.1mSv, not to mention the standards of 1mSv and 5mSv. That is, the shielding body 3 'can not only meet the radiation dose limit standard for professional personnel and the public in the national standard, but also meet the radiation dose limit standard in this embodiment.
  • the design of the composite shielding wall covered with the iron material layer 5 can reduce the wall thickness of the corresponding shielding body 3 'by at least one third, so that the wall thickness of the entire shielding body 3' is more uniform. Without reducing the shielding effect, the occupied space of the shielding body 3 'is reduced.
  • each wall thickness of the shielding body 3 'and the thickness of the iron material layer 5 are designed according to the maximum flow strength of the proton therapy system. In specific implementation, it can be based on the cost budget and actual needs. For the thickening process, this embodiment is limited to providing a lower limit value.
  • the rotating frame chamber 32 and the synchrotron chamber 31 communicate with each other, and no shielding wall is provided.
  • the purpose of this embodiment is to provide a verification method. No matter what shielding material is used to isolate the rotating gantry chamber 32 and the synchrotron chamber 31, for the target body 2, the radiation dose around the target body 2 will not Effectively reduce.
  • the simulation analysis of the radiation distribution of the shield 3 is performed according to the Monte Carlo algorithm.
  • the calculation is performed according to the maximum flow intensity of the proton therapy system 1, the effective dose (unit Gy) is used for comparative analysis, and the radiation dose near the scanning treatment head 15 and the target body 2 is focused on.
  • the radiation dose distribution diagram of the proton therapy system 1 shown in FIG. 8 shows from left to right that there is no shielding wall between the rotating gantry 32 room and synchrotron room 31, and a shielding wall with a 10 cm concrete layer 4 And the radiation dose distribution of the proton therapy system 1 in the case of a composite shielding wall composed of a 5 cm concrete layer 4 and a 2 cm iron material layer 5.
  • the scanning treatment head 15 emits a proton flow toward the target body 2, and in the direction perpendicular to the scanning treatment head 15 emission direction, three points at 15 cm, 50 cm, and 200 cm from the center of the target body 2 are selected (that is, For points A1, B1, C1), the dose value is extracted.
  • Table 2 The specific values are shown in Table 2:

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Abstract

A shielding apparatus for a proton therapy system. The shielding apparatus is a multi-compartment structure comprising a synchrotron compartment and a rotatable gantry compartment. The synchrotron compartment is in communication with the rotatable gantry compartment. The rotatable gantry compartment comprises an upper rotatable gantry compartment section, a lower rotatable gantry compartment section, and a gantry recess formed between the upper rotatable gantry compartment section and the lower rotatable gantry compartment section. The upper rotatable gantry compartment section is configured to be in communication with the synchrotron compartment.

Description

用于质子治疗系统的屏蔽体Shield for proton therapy system
本申请要求申请日为2018年11月07日、申请号为201811317523.3及申请日为2018年11月07日、申请号为201821825482.4的中国专利申请的优先权,该申请的全部内容通过引用结合在本申请中。This application requires the priority of the Chinese patent application with the application date of November 07, 2018, application number 201811317523.3 and application date of November 07, 2018, application number 201821825482.4. The entire content of the application is incorporated by reference in this document Applying.
技术领域Technical field
本公开涉及防辐射技术领域,例如涉及用于质子治疗系统的屏蔽体。The present disclosure relates to the technical field of radiation protection, for example, to a shield used in a proton therapy system.
背景技术Background technique
质子治疗被全世界公认为疗效最好、副作用最少的肿瘤治疗方法,而拥有360度旋转机架可以使质子束流在患者不移动的情况下,从多个角度按照最优路径准确轰击患者的肿瘤位置,耗时更少、对健康组织的伤害更少,同时使质子治疗技术能够运用于更多类型的肿瘤治疗。Proton therapy is recognized worldwide as the most effective tumor treatment method with the least side effects, and having a 360-degree rotating gantry allows the proton beam to accurately bombard the patient from multiple angles according to the optimal path without moving the patient The location of the tumor is less time-consuming and less harmful to healthy tissues, while enabling proton therapy technology to be applied to more types of tumor treatment.
在质子的加速旋转过程中,会产生大量有害公众健康的粒子辐射。基于辐射防护最优化原则,质子治疗系统的建造者应尽量减少质子治疗系统所产生的辐射,以减少对公众和环境的影响。During the accelerated rotation of protons, a large amount of particle radiation harmful to public health will be generated. Based on the principle of radiation protection optimization, the builder of the proton therapy system should minimize the radiation generated by the proton therapy system to reduce the impact on the public and the environment.
相关技术中的带有旋转机架的质子治疗系统通常设置于由混凝土构建的大型建筑中;但是该质子治疗系统的辐射屏蔽体都无法根据治疗系统的辐射剂量进行适形设计,而是采用过度防护,以尽可能大、尽可能厚的屏蔽体来减少辐射,使得屏蔽体占用空间大,建设成本高。屏蔽体材料种类和厚度决定造价,随着同步加速器的小型化发展,对于商用医疗质子治疗系统来说,设计一种经济适用且安全有效的屏蔽体迫在眉睫。The proton therapy system with a rotating gantry in the related art is usually installed in a large building made of concrete; however, the radiation shield of this proton therapy system cannot be conformally designed according to the radiation dose of the therapy system, but is over For protection, the shield body is as large and thick as possible to reduce radiation, so that the shield body occupies a large space and the construction cost is high. The type and thickness of the shielding material determine the cost. With the development of miniaturization of synchrotrons, it is urgent for commercial medical proton therapy systems to design an economical, safe, and effective shielding body.
发明内容Summary of the invention
本公开提供了一种用于质子治疗系统的屏蔽体,能够针对质子治疗系统的辐射进行针对性屏蔽,达到最佳防护,同时节约成本,减少空间占用。The present disclosure provides a shielding body for a proton therapy system, which can perform targeted shielding against the radiation of the proton therapy system to achieve the best protection, while saving costs and reducing space occupation.
用于质子治疗系统的屏蔽体,其中,所述屏蔽体为由屏蔽墙构建的多腔室结构,所述该屏蔽体包括同步加速器室及旋转机架室,所述同步加速器室和所述旋转机架室相互连通;所述旋转机架室包括上旋转机架室、下旋转机架室及开设于所述上旋转机架室和所述下旋转机架室之间的机架槽,所述上旋转机架 室位于所述下旋转机架室的上部,所述上旋转机架室设置为与所述同步加速器室相互连通并形成一个腔室。A shielding body for a proton therapy system, wherein the shielding body is a multi-chamber structure constructed by a shielding wall, the shielding body includes a synchrotron chamber and a rotating gantry chamber, the synchrotron chamber and the rotation The rack rooms communicate with each other; the rotating rack room includes an upper rotating rack room, a lower rotating rack room, and a rack slot opened between the upper rotating rack room and the lower rotating rack room. The upper rotating frame chamber is located at an upper part of the lower rotating frame chamber, and the upper rotating frame chamber is arranged to communicate with the synchrotron chamber and form a cavity.
附图概述Brief description of the drawings
图1是施例一提供的质子治疗系统的结构示意图;1 is a schematic structural diagram of a proton therapy system provided in Example 1;
图2是实施例二提供的屏蔽体每个腔室剖开的结构示意图;FIG. 2 is a schematic structural view of each chamber of the shielding body provided in Embodiment 2 cut away;
图3是实施例二提供的屏蔽体中间横截面上的剂量分布图;3 is a dose distribution diagram of the intermediate cross-section of the shielding body provided in Embodiment 2;
图4是实施例二提供的屏蔽体中间纵截面上的剂量分布图;4 is a dose distribution diagram on the middle longitudinal section of the shielding body provided in Embodiment 2;
图5是实施例三提供的屏蔽体每个腔室剖开的结构示意图;5 is a schematic structural view of each chamber of the shielding body provided in Embodiment 3 cut away;
图6是实施例三提供的屏蔽体中间横截面上的剂量分布图;6 is a dose distribution diagram of the intermediate cross section of the shielding body provided in Embodiment 3;
图7是实施例三提供的屏蔽体中间纵截面上的剂量分布图;7 is a dose distribution diagram on the middle longitudinal section of the shield provided by the third embodiment;
图8是实施例四中设置不同屏蔽墙情况下的质子治疗系统的辐射剂量分布图;8 is a radiation dose distribution diagram of the proton therapy system in the case of setting different shielding walls in the fourth embodiment;
图9是实施例四中扫描治疗头与靶体的作用示意图。9 is a schematic diagram of the function of scanning the treatment head and the target body in the fourth embodiment.
图中:In the picture:
1-质子治疗系统;1-Proton therapy system;
11-注入器;12-同步加速器;13-引出装置;14-旋转机架;15-扫描治疗头;11-injector; 12-synchrotron; 13-extraction device; 14-rotating gantry; 15-scanning treatment head;
2-靶体;2- target body;
3、3′-屏蔽体;3. 3′-shield body;
31、31′-同步加速器室;32、32′-旋转机架室;321、321′-上旋转机架室;322、322′-下旋转机架室;323、323′-机架槽;33、33′-治疗室;34、34′-迷宫室;35、35′-设备室;31, 31 '-synchrotron room; 32, 32'-rotating frame room; 321, 321 '-upper rotating frame room; 322, 322'-lower rotating frame room; 323, 323 '-frame slot; 33, 33′-treatment room; 34, 34′-maze room; 35, 35′-equipment room;
4-混凝土层;5-铁材料层。4- concrete layer; 5- iron material layer.
具体实施方式detailed description
实施例一Example one
本实施例提供一种用于质子治疗系统的屏蔽体,如图1所示,该质子治疗系统1为360°旋转机架质子治疗系统,包括了顺次连接的注入器11、同步加速器12、引出装置13、旋转机架14和扫描治疗头15。质子由注入器11注入至同步加速器12中,经过同步加速器12加速获得能量形成质子束流,质子束流由引出装置13的引出磁铁导流至旋转机架14中,经由旋转机架14的三个二极磁铁后由扫描治疗头15射出至靶体2(即患者的病灶),完成治疗。其中,质子束流在同步 加速器12的二极磁铁、引出磁铁及旋转机架14的三个二极磁铁以及扫描治疗头15上会发生较大的束流损失,产生较强的辐射能量,因此,在进行辐射屏蔽体的设计时需要重点关注这些区域的防辐射。This embodiment provides a shield for a proton therapy system. As shown in FIG. 1, the proton therapy system 1 is a 360 ° rotating gantry proton therapy system, which includes an injector 11 and a synchrotron 12 connected in sequence. The extraction device 13, the rotating gantry 14 and the scanning treatment head 15. The protons are injected into synchrotron 12 by injector 11 and accelerated by synchrotron 12 to obtain energy to form a proton beam. The proton beam is guided by the magnet of the extraction device 13 to the rotating frame 14 through the three of the rotating frame 14 After a two-pole magnet is emitted from the scanning treatment head 15 to the target body 2 (ie, the lesion of the patient), the treatment is completed. Among them, the proton beam will cause a large beam loss on the two-pole magnet of the synchrotron 12, the three-pole magnet of the extraction magnet and the rotating gantry 14, and the scanning treatment head 15, resulting in strong radiation energy, so In the design of radiation shields, it is necessary to focus on the radiation protection in these areas.
如图2所示,屏蔽体3整体为屏蔽墙构建的多腔室结构,包括同步加速器室31、旋转机架室32、治疗室33、迷宫室34和设备室35。其中,注入器11、同步加速器12和引出装置13设置于同步加速器室31内,旋转机架14设置于旋转机架室32内,扫描治疗头15和靶体2位于治疗室33内,设备室35设置为放置质子治疗系统1的电气设备。As shown in FIG. 2, the shield body 3 is a multi-chamber structure constructed by a shield wall as a whole, including a synchrotron room 31, a rotating gantry room 32, a treatment room 33, a labyrinth room 34 and an equipment room 35. Among them, the injector 11, synchrotron 12 and extraction device 13 are arranged in the synchrotron chamber 31, the rotating frame 14 is arranged in the rotating frame chamber 32, the scanning treatment head 15 and the target body 2 are located in the treatment room 33, the equipment room 35 is set to place electrical equipment of the proton therapy system 1.
同步加速器室31和旋转机架室32相互连通,且不设有任何屏蔽结构,成为一个整体的腔室,如此设置可以节省空间,也减少了屏蔽材料的浪费。另外由于旋转机架14在竖直方向占用的空间较大,旋转机架室32可分为上部的上旋转机架室321和下部的下旋转机架室322,上旋转机架室321和下旋转机架室322之间开设有机架槽323,旋转机架14贯穿所述机架槽323设置;机架槽323的形状结构根据旋转机架14的结构进行设计,避免过多的辐射由下旋转机架室322透出。上旋转机架室321与同步加速器室31相互连通。The synchrotron chamber 31 and the rotating gantry chamber 32 communicate with each other, and do not have any shielding structure, forming a whole chamber. This arrangement can save space and also reduce the waste of shielding materials. In addition, because the rotating frame 14 occupies a large space in the vertical direction, the rotating frame chamber 32 can be divided into an upper upper rotating frame chamber 321 and a lower lower rotating frame chamber 322, the upper rotating frame chamber 321 and the lower A rack slot 323 is provided between the rotating rack chambers 322, and the rotating rack 14 is disposed through the rack slot 323; the shape and structure of the rack slot 323 are designed according to the structure of the rotating rack 14 to avoid excessive radiation The lower rotating rack chamber 322 penetrates. The upper rotating frame chamber 321 and the synchrotron chamber 31 communicate with each other.
旋转机架室32和治疗室33之间设有隔离墙(在图中并未显示),该隔离墙可为简单的墙体结构,可采用木板、塑料板等隔离材料制造,而不采用混凝土制造,即隔离墙只需起到将治疗室33和旋转机架室32隔离的目的即可。旋转机架室32与治疗室33的这种隔离设计可以节省屏蔽体的制造成本,避免过多屏蔽材料的浪费。There is a partition wall (not shown in the figure) between the rotating gantry room 32 and the treatment room 33. The partition wall can be a simple wall structure, which can be made of insulating materials such as wooden boards and plastic boards instead of concrete The manufacturing, that is, the separation wall only needs to isolate the treatment room 33 and the rotating gantry room 32. The isolation design of the rotating gantry room 32 and the treatment room 33 can save the manufacturing cost of the shield body and avoid the waste of excessive shielding materials.
迷宫室34设置于上旋转机架室321的一侧,并与治疗室33相互连通,方便操作人员由迷宫进入治疗室33,帮助患者进行定位和治疗。迷宫室34设有迷宫进口和迷宫出口,迷宫进口设于迷宫室外侧,与外界连通,迷宫出口与治疗室33相互连通,操作人员由迷宫进口进入迷宫中,并由迷宫出口进入至治疗室33。The labyrinth room 34 is disposed on one side of the upper rotating gantry room 321, and communicates with the treatment room 33, so that the operator can enter the treatment room 33 from the labyrinth to help the patient to perform positioning and treatment. The labyrinth room 34 is provided with a labyrinth entrance and a labyrinth exit. The labyrinth entrance is located outside the labyrinth and communicates with the outside world. The labyrinth exit and the treatment room 33 are interconnected. .
设备室35设置于迷宫室34的下方,并位于下旋转机架室322的一侧,设备室35内放置整个质子治疗系统1的电气设备,设备35室与下旋转机架室322之间相互连通,并设置为将电气设备与质子治疗系统1的多个部件连接。The equipment room 35 is provided below the labyrinth room 34 and is located on one side of the lower rotating gantry room 322. The entire proton therapy system 1 electrical equipment is placed in the equipment room 35. The equipment 35 room and the lower rotating gantry room 322 are mutually connected. Connected and set to connect electrical equipment to multiple components of the proton therapy system 1.
本实施例的旋转机架室32和同步加速器室31相互连通,不设有屏蔽墙,旋转机架室32和治疗室33之间设有隔离墙(不是屏蔽墙),降低了屏蔽体3建造成本;本实施例对屏蔽体3进行适形的结构设计和厚度设计,使得屏蔽体3能够以最小的空间达到防护目的,同时也节约了建造成本,有利于商业推广;本实施 例的屏蔽体3采用混凝土和铁材料为屏蔽材料,能够进一步减少屏蔽体3的厚度设置,减少了屏蔽体3的占用空间。The rotating gantry chamber 32 and the synchrotron chamber 31 of this embodiment communicate with each other without a shielding wall, and a separating wall (not a shielding wall) is provided between the rotating gantry chamber 32 and the treatment room 33, which reduces the construction of the shielding body 3 Cost; in this embodiment, the shielding body 3 is designed with a conformal structure and thickness, so that the shielding body 3 can achieve the protection purpose with the smallest space, and also saves the construction cost, which is beneficial to commercial promotion; the shielding body of this embodiment 3. The use of concrete and iron materials as shielding materials can further reduce the thickness setting of the shielding body 3 and reduce the space occupied by the shielding body 3.
实施例二Example 2
如实施例一所述的屏蔽体3,屏蔽体3的屏蔽墙为混凝土层4,每个腔室的高度和体积根据质子治疗系统1的每个部分的结构大小进行设计,但本实施例可以提供关于该屏蔽体3的具体壁厚尺寸的下限值,该下限值根据位于该屏蔽体3内的质子治疗系统1使用时的最大辐射量进行适形设置。The shielding body 3 as described in the first embodiment, the shielding wall of the shielding body 3 is a concrete layer 4, the height and volume of each chamber are designed according to the structure size of each part of the proton therapy system 1, but this embodiment can The lower limit value of the specific wall thickness dimension of the shield body 3 is provided, and the lower limit value is conformally set according to the maximum radiation amount when the proton therapy system 1 located in the shield body 3 is used.
如图2中的坐标系所示,本实施例中所述的上或下的方向为Z轴方向,左、或右的方向为Y轴方向,前或后的方向为X轴方向,以便理解。As shown in the coordinate system in FIG. 2, the up or down direction in this embodiment is the Z-axis direction, the left or right direction is the Y-axis direction, and the front or back direction is the X-axis direction for easy understanding. .
在一实施例中,同步加速器室31的上壁厚度和下壁厚度设置为2m,同步加速器室31的左壁厚度设置为2m,其中左壁下部的厚度可以加厚至3m,以获得更安全的屏蔽效果。In an embodiment, the thickness of the upper wall and the lower wall of the synchrotron chamber 31 are set to 2m, and the thickness of the left wall of the synchrotron chamber 31 is set to 2m, where the thickness of the lower part of the left wall can be thickened to 3m for more safety Shielding effect.
上旋转机架室321的下壁厚度也设置为2m,上壁厚度为3m,右壁厚度设置为2m,上旋转机架室321的右壁设置为隔离上旋转机架室321和迷宫室34;其中,右壁靠近后侧的部分的厚度设置为3m。The thickness of the lower wall of the upper rotating rack chamber 321 is also set to 2m, the thickness of the upper wall is 3m, the thickness of the right wall is set to 2m, and the right wall of the upper rotating rack chamber 321 is set to isolate the upper rotating rack chamber 321 and the labyrinth chamber 34 ; Among them, the thickness of the part of the right wall near the rear side is set to 3m.
在一实施例中,整个同步加速器室31、上旋转机架室321的前壁和上旋转机架室321的后壁的厚度均设为3m。In an embodiment, the thicknesses of the entire synchrotron chamber 31, the front wall of the upper rotating frame chamber 321, and the rear wall of the upper rotating frame chamber 321 are all set to 3 m.
下旋转机架室322的上壁即为上旋转机架室321的下壁,下旋转机架室322的侧壁、前壁和后壁厚度均为2m,下壁厚度为3m。The upper wall of the lower rotating frame chamber 322 is the lower wall of the upper rotating frame chamber 321, and the thickness of the side wall, front wall and rear wall of the lower rotating frame chamber 322 is 2m, and the thickness of the lower wall is 3m.
迷宫室34的上壁、下壁、右壁以及后壁厚度均设置为1m,而迷宫室34的前壁厚度设置为2m。The thickness of the upper wall, the lower wall, the right wall, and the rear wall of the labyrinth chamber 34 are all set to 1 m, and the thickness of the front wall of the labyrinth chamber 34 is set to 2 m.
为了进一步增强上旋转机架室321的防辐射能力,在上旋转机架室321右壁的外侧上加设有一层屏蔽墙,该屏蔽墙位于迷宫室34的上方,厚度设为0.5m。In order to further enhance the radiation resistance of the upper rotating frame chamber 321, a layer of shielding wall is added on the outer side of the right wall of the upper rotating frame chamber 321, the shielding wall is located above the labyrinth chamber 34, and the thickness is set to 0.5m.
设备室35的上壁即为迷宫室34的下壁,设备室35与下旋转机架室322通过下旋转机架室322的右壁进行隔离,设备室35的前壁、后壁、下壁和右壁厚度均为0.5m。The upper wall of the equipment room 35 is the lower wall of the labyrinth room 34. The equipment room 35 and the lower rotating rack room 322 are separated by the right wall of the lower rotating rack room 322, and the front wall, rear wall, and lower wall of the equipment room 35 The thickness of the right wall is 0.5m.
针对辐射剂量的标准,国标GB18871-2002的要求是:职业照射年剂量小于20毫希(mSv),公众照射年剂量小于1mSv。而本实施例所提供的屏蔽体3的设计目标是职业照射年剂量小于5mSv,为国标的1/4,公众照射年剂量小于0.1mSv,为国标的1/10,具体如表1所示:Regarding the radiation dose standard, the requirements of the national standard GB18871-2002 are: occupational exposure annual dose is less than 20 mSv, and public exposure annual dose is less than 1mSv. The design goal of the shielding body 3 provided in this embodiment is that the annual dose of occupational exposure is less than 5mSv, which is 1/4 of the national standard, and the annual dose of public exposure is less than 0.1mSv, which is 1/10 of the national standard, as shown in Table 1:
表1辐射剂量标准(单位:mSv/每年)Table 1 Radiation dose standard (unit: mSv / year)
Figure PCTCN2019073198-appb-000001
Figure PCTCN2019073198-appb-000001
针对以上屏蔽体3具体的壁厚设计,根据蒙特洛卡算法进行该屏蔽体3辐射量分布的模拟分析,验证本实施的屏蔽体3的结构和厚度的设计可以满足防辐射要求。本实施例中质子治疗系统1的引出质子能力范围为70-230兆电子伏特(MeV),最大流强2nA,在计算时按照质子治疗系统1的最大流强进行分析,选用当量剂量(单位为mSv)进行对比分析,得到如图3-图4所示的辐射剂量分布图。According to the specific wall thickness design of the above shielding body 3, a simulation analysis of the radiation amount distribution of the shielding body 3 is performed according to the Monte Carlo algorithm, and it is verified that the design of the structure and thickness of the shielding body 3 of the present embodiment can meet the requirements of radiation protection. In this embodiment, the proton therapy system 1 has a proton extraction capability in the range of 70-230 megaelectron volts (MeV) and a maximum flow intensity of 2nA. When calculating, the proton therapy system 1 is analyzed according to the maximum flow intensity, and the equivalent dose (unit is mSv) for comparative analysis to obtain the radiation dose distribution diagrams shown in Figures 3-4.
图3为该屏蔽体3中间横截面上的剂量分布图,图3的下方为剂量分布数值的图示,图3上标有三个标准线,由左至右分别为0.1mSv、1mSv和5mSv,在分布图中相应地勾画出上述标准线的连线图,可以看到,每个标准线几乎都落在了屏蔽体3的侧壁上,其中,最外侧的曲线为0.1mSv的剂量线,中间曲线为1mSv的剂量线,最内侧的曲线为5mSv的剂量线,证明了该屏蔽体3可以屏蔽辐射至0.1mSv的标准。即该屏蔽体3既能满足国标中对职业人员以及公众的辐射剂量限值标准,也能满足本实施例对辐射剂量的限值标准。Figure 3 is the dose distribution diagram of the shield 3 in the middle cross section. The lower part of Figure 3 is a graphical representation of the dose distribution value. Figure 3 is marked with three standard lines, from left to right are 0.1mSv, 1mSv and 5mSv, In the distribution diagram, correspondingly draw the connection diagram of the above standard lines. It can be seen that each standard line almost falls on the side wall of the shield 3, wherein the outermost curve is the dose line of 0.1mSv, The middle curve is the dose line of 1 mSv, and the innermost curve is the dose line of 5 mSv, which proves that the shielding body 3 can shield the standard of radiating to 0.1 mSv. That is, the shielding body 3 can meet not only the radiation dose limit standard for professional personnel and the public in the national standard, but also the radiation dose limit standard in this embodiment.
图4为该屏蔽体3中间纵截面上的剂量分布图,图4的下方为剂量分布数值的图示,图4上标有三个标准线,由左至右分别为0.1mSv、1mSv和5mSv,在分布图中相应地勾画出上述标准的连线图,可以看到,每个标准线几乎都落在了屏蔽体3的侧壁上,其中,最外侧的曲线为0.1mSv的剂量线,中间曲线为1mSv的剂量线,最内侧的曲线为5mSv的剂量线,证明了该屏蔽体3可以屏蔽辐射至0.1mSv的标准。即该屏蔽体3既能满足国标中对职业人员以及公众的辐射剂量限值标准,也能满足本实施例对辐射剂量的限值标准。Fig. 4 is a dose distribution diagram on the middle longitudinal section of the shield 3, and the lower part of Fig. 4 is a graphical representation of the dose distribution values. There are three standard lines marked on Fig. 4, from left to right are 0.1mSv, 1mSv and 5mSv, In the distribution diagram, correspondingly draw the above standard wiring diagram. It can be seen that each standard line almost falls on the side wall of the shield 3, wherein the outermost curve is the dose line of 0.1mSv, the middle The curve is a dose line of 1 mSv, and the innermost curve is a dose line of 5 mSv, which proves that the shielding body 3 can shield the standard of radiating to 0.1 mSv. That is, the shielding body 3 can meet not only the radiation dose limit standard for professional personnel and the public in the national standard, but also the radiation dose limit standard in this embodiment.
本实施例中屏蔽体3的每个壁厚均根据最小值进行设计选取的,具体实施时,可以根据造价预算的高低和实际需求进行增厚处理,本实施例仅限于提供一个按照质子治疗系统1的最大流强进行设计的壁厚下限值。In this embodiment, each wall thickness of the shielding body 3 is designed and selected according to the minimum value. In specific implementation, it can be thickened according to the level of the cost budget and actual needs. This embodiment is limited to providing a proton therapy system. 1 The lower limit of the wall thickness for which the maximum flow intensity is designed.
实施例三Example Three
本实施例在于提供一种屏蔽体3′,与实施例二中的屏蔽体3结构基本相同, 但与实施例二中的屏蔽体3不同的是,该屏蔽体3′采用混凝土层4和铁材料层5形成的复合屏蔽墙来构建腔室结构。This embodiment is to provide a shield body 3 ', which has basically the same structure as the shield body 3 in the second embodiment, but differs from the shield body 3 in the second embodiment in that the shield body 3' uses a concrete layer 4 and iron The composite shielding wall formed by the material layer 5 constructs the cavity structure.
采用复合屏蔽墙的情况下,每个腔室的高度和体积仍根据质子治疗系统1每个部分的结构大小进行设计,由于铁材料是良好的屏蔽材料,包覆有铁材料的复合屏蔽墙的防辐射能力更强,混凝土材料和铁材料的组合能够减少屏蔽层的厚度,因此每个腔室壁厚的下限值会有所改变,但该下限值仍根据质子治疗系统1的辐射分布进行适形的设置。In the case of a composite shielding wall, the height and volume of each chamber are still designed according to the structural size of each part of the proton therapy system 1. Since iron material is a good shielding material, the composite shielding wall covered with iron material The radiation resistance is stronger, the combination of concrete and iron materials can reduce the thickness of the shielding layer, so the lower limit of the wall thickness of each chamber will change, but the lower limit is still based on the radiation distribution of the proton therapy system 1 Make conformable settings.
本实施例中,复合屏蔽墙采用铁材料层5包覆在混凝土层4内壁上形成,且根据辐射剂量的分布,并不是所有的混凝土层4上均包覆有铁材料层5,只有在辐射剂量较多的区域进行铁材料层5的包覆。应当注意的是,以下所提及的屏蔽体3′的壁厚如果没有特别说明,均指屏蔽墙的整体厚度,即若只是单纯的混凝土层4,则壁厚就为混凝土层4的厚度;若是复合屏蔽墙,则壁厚就为混凝土层4和铁材料层5的整体厚度,且针对铁材料层厚度设计均有相应的特别说明。In this embodiment, the composite shielding wall is formed by coating the inner wall of the concrete layer 4 with the iron material layer 5, and according to the radiation dose distribution, not all the concrete layers 4 are covered with the iron material layer 5, only during radiation The iron material layer 5 is coated in the area with a large dose. It should be noted that the wall thickness of the shielding body 3 'mentioned below refers to the overall thickness of the shielding wall unless otherwise specified, that is, if it is only the concrete layer 4, the wall thickness is the thickness of the concrete layer 4; If it is a composite shield wall, the wall thickness is the overall thickness of the concrete layer 4 and the iron material layer 5, and there are corresponding special instructions for the thickness design of the iron material layer.
如图5所示,同步加速器室31′的上壁和下壁厚度设置为2m,同步加速器室31′的左壁厚度设置为2m,其中左壁的下部包覆有铁材料层5,铁材料层5厚度为30cm,该铁材料层5替代了原来此处增加的1m厚的混凝土层4,但可达到相同的屏蔽效果,使得同步加速器室31′的左壁均为2m。同步加速器室31′的下壁上包覆有长为700cm、宽为600cm及厚度为60cm的矩形铁材料层5。As shown in FIG. 5, the thickness of the upper and lower walls of the synchrotron chamber 31 'is set to 2m, and the thickness of the left wall of the synchrotron chamber 31' is set to 2m, wherein the lower part of the left wall is covered with a layer of iron material 5, iron material Layer 5 has a thickness of 30 cm. The iron material layer 5 replaces the 1 m thick concrete layer 4 added here, but the same shielding effect can be achieved, so that the left wall of the synchrotron chamber 31 ′ is 2 m. The lower wall of the synchrotron chamber 31 'is covered with a rectangular iron material layer 5 having a length of 700 cm, a width of 600 cm and a thickness of 60 cm.
上旋转机架室321′的上壁和下壁厚度均设置为2m,上旋转机架室右壁厚度设置为2m,设置为隔离上旋转机架室321′和迷宫室34′;其中,上旋转机架室321′的上壁的侧壁上包覆有100cm的铁材料层5,可以替代原来此处增加的1m厚的混凝土层4;上旋转机架室321′的右壁靠近后侧的部分包覆有50cm的铁材料层5,用来替代原来此处设计的1m厚的混凝土层4。The thickness of the upper and lower walls of the upper rotating rack chamber 321 'are set to 2m, and the thickness of the right wall of the upper rotating rack chamber is set to 2m, which is set to isolate the upper rotating rack chamber 321' and the labyrinth chamber 34 '; The side wall of the upper wall of the rotating frame room 321 'is covered with a layer of iron material 5 of 100 cm, which can replace the 1 m thick concrete layer 4 added here; the right wall of the upper rotating frame room 321' is close to the rear side The part is covered with a 50 cm layer of iron material 5 to replace the 1 m thick concrete layer 4 originally designed here.
下旋转机架室322′的上壁即为上旋转机架室321′的下壁,下旋转机架室322′的侧壁厚为2m,下壁壁厚为2m。其中在下旋转机架室322′的侧壁上均包覆有50cm厚的铁材料层5,在下旋转机架室322′下壁的右侧部分包覆有60cm厚的铁材料层5,如此设置可以将下旋转机架室322′的下壁有效地减少了1m的厚度。The upper wall of the lower rotating frame chamber 322 'is the lower wall of the upper rotating frame chamber 321', the side wall thickness of the lower rotating frame chamber 322 'is 2m, and the wall thickness of the lower wall is 2m. The side walls of the lower rotating frame chamber 322 'are covered with a 50cm thick iron material layer 5, and the right side portion of the lower wall of the lower rotating frame chamber 322' is covered with a 60cm thick iron material layer 5, so set The lower wall of the lower rotating frame chamber 322 'can be effectively reduced by 1 m in thickness.
整个同步加速器室31′和上旋转机架室321′的前壁和后壁的厚度均设为2m,较实施例二中壁厚为3m的设置,整个壁厚减少了三分之一,因为在同步加速器室31′和上旋转机架室321′的前壁和后壁上均包覆有铁材料层5。在一实施例 中,铁材料层5在同步加速器室31′后壁上设置为50cm,在同步加速器室31′前壁上设置为20cm;但是铁材料层5在上旋转机架室321′后壁上设置的厚度增加为100cm,在上旋转机架室321′前壁上设置为70cm,主要原因是根据图3中剂量标准线,在上旋转机架室321′的前壁和后壁上的辐射剂量较同步加速器室31′的前壁和后壁的剂量多,因此需要将上旋转机架室321′铁材料层5的厚度设置的厚些。The thicknesses of the front wall and the rear wall of the entire synchrotron chamber 31 'and the upper rotating frame chamber 321' are set to 2m, which is one-third lower than the setting of the wall thickness of 3m in the second embodiment, because The front wall and the rear wall of the synchrotron chamber 31 'and the upper rotating frame chamber 321' are covered with a layer 5 of iron material. In one embodiment, the iron material layer 5 is set to 50 cm on the rear wall of the synchrotron chamber 31 'and 20 cm on the front wall of the synchrotron chamber 31'; but the iron material layer 5 is behind the upper rotating frame chamber 321 ' The thickness of the wall is increased to 100cm, and it is set to 70cm on the front wall of the upper rotating gantry chamber 321 '. The main reason is that according to the standard dose line in Figure 3, on the front and rear walls of the upper rotating gantry chamber 321' The radiation dose is greater than the dose of the front wall and the rear wall of the synchrotron chamber 31 ', so the thickness of the iron material layer 5 of the upper rotating frame chamber 321' needs to be set thicker.
迷宫室34′的上壁厚度、下壁厚度、右壁以及后壁厚度均设置为1m,而前壁厚度设置为2m。The thickness of the upper wall, the thickness of the lower wall, the thickness of the right wall and the rear wall of the labyrinth chamber 34 'are all set to 1m, and the thickness of the front wall is set to 2m.
为了进一步增强上旋转机架室321′的防辐射能力,在上旋转机架室321′的右壁的外壁上加设有一层屏蔽墙,该屏蔽墙位于迷宫室34′的上方,厚度设为0.5m。In order to further enhance the radiation resistance of the upper rotating rack chamber 321 ', a layer of shielding wall is added to the outer wall of the right wall of the upper rotating rack chamber 321', and the shielding wall is located above the labyrinth chamber 34 'with a thickness of 0.5m.
设备室35′的上壁即为迷宫室34′的下壁,设备室35′的下壁和右壁厚度均为0.5m,设备室35′与下旋转机架室322′通过下旋转机架室322′的右壁进行隔离。The upper wall of the equipment room 35 'is the lower wall of the labyrinth room 34'. The thickness of the lower and right walls of the equipment room 35 'is 0.5m. The equipment room 35' and the lower rotating rack room 322 'pass through the lower rotating rack The right wall of chamber 322 'is isolated.
由于辐射在迷宫室34′和设备室35′内剂量较少,本实施例中针对设备室35′和迷宫室34′不再设置铁材料层5。Since the radiation dose in the labyrinth room 34 'and the equipment room 35' is small, the iron material layer 5 is no longer provided for the equipment room 35 'and the labyrinth room 34' in this embodiment.
根据实施例二所述,针对本实施例中屏蔽体3′具体的壁厚设计,利用蒙特洛卡算法进行该屏蔽体3′辐射量分布的模拟分析,验证本实施例的屏蔽体3′的结构和厚度的设计可以满足防辐射要求,计算时仍按照质子治疗系统的最大流强进行分析,得到如图6-图7所示的辐射剂量分布图。According to the second embodiment, for the specific wall thickness design of the shield 3 ′ in this embodiment, a Monte Carlo algorithm is used to simulate and analyze the radiation distribution of the shield 3 ′ to verify the shield 3 ′ of this embodiment. The design of the structure and thickness can meet the requirements of radiation protection. During the calculation, the maximum flow intensity of the proton therapy system is still used for analysis, and the radiation dose distribution diagram shown in FIGS. 6 to 7 is obtained.
图6为该屏蔽体3′中间横截面上的剂量分布图,图6的下方为剂量分布数值的图示,图6上标有三个标准线,由左至右分别为0.1mSv、1mSv和5mSv,在分布图中相应地勾画出上述标准的连线图,可以看到,每个标准线仍然几乎都落在了屏蔽体3′的侧壁上,其中,最外侧的曲线为0.1mSv的剂量线,中间曲线为1mSv的剂量线,最内侧的曲线为5mSv的剂量线,证明了该屏蔽体3′可以屏蔽辐射至0.1mSv的标准,更不用说1mSv和5mSv的标准了。即该屏蔽体3′既能满足国标中对职业人员以及公众的辐射剂量限值标准,也能满足本实施例对辐射剂量的限值标准。Fig. 6 is the dose distribution diagram of the shield 3 'in the middle cross section. The lower part of Fig. 6 is a graphical representation of the dose distribution values. There are three standard lines marked on Fig. 6, from left to right are 0.1mSv, 1mSv and 5mSv , Correspondingly draw the above standard wiring diagram in the distribution diagram, you can see that each standard line still almost falls on the side wall of the shield 3 ', where the outermost curve is the dose of 0.1mSv Line, the middle curve is the dose line of 1mSv, and the innermost curve is the dose line of 5mSv, which proves that the shield 3 'can shield the standard of radiation to 0.1mSv, not to mention the standards of 1mSv and 5mSv. That is, the shielding body 3 'can not only meet the radiation dose limit standard for professional personnel and the public in the national standard, but also meet the radiation dose limit standard in this embodiment.
图7为该屏蔽体3′中间纵截面上的剂量分布图,图7的下方为剂量分布数值的图示,图7上标有三个标准线,由左至右分别为0.1mSv、1mSv和5mSv,在分布图中相应地勾画出上述标准的连线图,可以看到,每个标准线几乎都落在了屏 蔽体3′的侧壁上,其中,最外侧的曲线为0.1mSv的剂量线,中间曲线为1mSv的剂量线,最内侧的曲线为5mSv的剂量线,证明了该屏蔽体3′可以屏蔽辐射至0.1mSv的标准,更不用说1mSv和5mSv的标准了。即该屏蔽体3′既能满足国标中对职业人员以及公众的辐射剂量限值标准,也能满足本实施例对辐射剂量的限值标准。Fig. 7 is the dose distribution diagram of the shield 3 'in the middle longitudinal section. The lower part of Fig. 7 is a graph of the dose distribution values. There are three standard lines marked on Fig. 7, from left to right are 0.1mSv, 1mSv and 5mSv , Correspondingly draw the above standard wiring diagram in the distribution diagram. It can be seen that each standard line almost falls on the side wall of the shield 3 ′, where the outermost curve is the dose line of 0.1mSv The middle curve is the dose line of 1mSv, and the innermost curve is the dose line of 5mSv, which proves that the shield 3 'can shield the standard of radiating to 0.1mSv, not to mention the standards of 1mSv and 5mSv. That is, the shielding body 3 'can not only meet the radiation dose limit standard for professional personnel and the public in the national standard, but also meet the radiation dose limit standard in this embodiment.
由此可见,采用包覆有铁材料层5的复合屏蔽墙进行设计,可以将相应的屏蔽体3′的壁厚减少至少三分之一,使得整个屏蔽体3′的壁厚更加均匀,在不降低屏蔽效果的前提下,减少了屏蔽体3′的占用空间。It can be seen that the design of the composite shielding wall covered with the iron material layer 5 can reduce the wall thickness of the corresponding shielding body 3 'by at least one third, so that the wall thickness of the entire shielding body 3' is more uniform. Without reducing the shielding effect, the occupied space of the shielding body 3 'is reduced.
本实施例中屏蔽体3′的每个壁厚、以及铁材料层5的厚度是按照质子治疗系统的最大流强进行设计的最小值,具体实施时,可以根据造价预算的高低和实际需求进行增厚处理,本实施例仅限于提供一个下限值。In this embodiment, each wall thickness of the shielding body 3 'and the thickness of the iron material layer 5 are designed according to the maximum flow strength of the proton therapy system. In specific implementation, it can be based on the cost budget and actual needs. For the thickening process, this embodiment is limited to providing a lower limit value.
实施例四Example 4
实施例一中提到,旋转机架室32和同步加速器室31之间相互连通,并未设置屏蔽墙。本实施例的目的在于提供一种验证方法,该验证方法无论采用何种屏蔽材料隔离旋转机架室32和同步加速器室31,对于靶体2来说,靶体2周围的辐射剂量均不会有效地减少。As mentioned in the first embodiment, the rotating frame chamber 32 and the synchrotron chamber 31 communicate with each other, and no shielding wall is provided. The purpose of this embodiment is to provide a verification method. No matter what shielding material is used to isolate the rotating gantry chamber 32 and the synchrotron chamber 31, for the target body 2, the radiation dose around the target body 2 will not Effectively reduce.
根据蒙特洛卡算法进行该屏蔽体3辐射量分布的模拟分析。在一实施例中,计算时按照质子治疗系统1的最大流强进行分析,选用有效剂量(单位为Gy)进行对比分析,并重点关注扫描治疗头15和靶体2附近的辐射剂量。The simulation analysis of the radiation distribution of the shield 3 is performed according to the Monte Carlo algorithm. In one embodiment, the calculation is performed according to the maximum flow intensity of the proton therapy system 1, the effective dose (unit Gy) is used for comparative analysis, and the radiation dose near the scanning treatment head 15 and the target body 2 is focused on.
如图8所示的质子治疗系统1的辐射剂量分布图,由左至右分别显示了旋转机架32室和同步加速器室31之间不设有屏蔽墙、设有10cm混凝土层4的屏蔽墙、以及设有由5cm混凝土层4和2cm铁材料层5组成的复合屏蔽墙的情况下,质子治疗系统1的辐射剂量分布。如图9所示,扫描治疗头15向靶体2进行质子流的发射,在垂直于扫描治疗头15发射的方向上,选取距离靶体2中心15cm、50cm、200cm处的三个点(即为点A1、B1、C1)进行剂量值的提取。具体数值如表2所示:The radiation dose distribution diagram of the proton therapy system 1 shown in FIG. 8 shows from left to right that there is no shielding wall between the rotating gantry 32 room and synchrotron room 31, and a shielding wall with a 10 cm concrete layer 4 And the radiation dose distribution of the proton therapy system 1 in the case of a composite shielding wall composed of a 5 cm concrete layer 4 and a 2 cm iron material layer 5. As shown in FIG. 9, the scanning treatment head 15 emits a proton flow toward the target body 2, and in the direction perpendicular to the scanning treatment head 15 emission direction, three points at 15 cm, 50 cm, and 200 cm from the center of the target body 2 are selected (that is, For points A1, B1, C1), the dose value is extracted. The specific values are shown in Table 2:
表2不同情况下靶体附近的辐射剂量分布(单位:Gy)Table 2 Radiation dose distribution near the target under different conditions (unit: Gy)
Figure PCTCN2019073198-appb-000002
Figure PCTCN2019073198-appb-000002
由表格数据可得,不设有屏蔽墙,设有10cm混凝土层的屏蔽墙、以及设有由5cm混凝土层和2cm铁材料层5组成的复合屏蔽墙的三种情况下,靶体2周围的辐射剂量变化不大,因此无论采用哪种屏蔽材料均不能有效减少靶体2周围的辐射剂量,为实施例一种同步加速器室31和旋转机架室32设置为一体式腔体结构提供了支持,该结构设计可以优化屏蔽体的结构,使屏蔽体小型化成为现实。It can be obtained from the table data that there are no shielding walls, a shielding wall with a 10cm concrete layer, and a composite shielding wall composed of a 5cm concrete layer and a 2cm iron material layer 5 around the target 2 The radiation dose does not change much, so no matter what kind of shielding material is used, the radiation dose around the target body 2 cannot be effectively reduced, which provides support for the embodiment of a synchrotron chamber 31 and a rotating gantry chamber 32 arranged in an integrated cavity structure The structure design can optimize the structure of the shield body and make the miniaturization of the shield body a reality.

Claims (10)

  1. 用于质子治疗系统的屏蔽体,其中,所述屏蔽体(3)为由屏蔽墙构建的多腔室结构,所述该屏蔽体(3)包括同步加速器室(31)及旋转机架室(32),所述同步加速器室(31)和所述旋转机架室(32)相互连通;A shield body for a proton therapy system, wherein the shield body (3) is a multi-chamber structure constructed by a shield wall, and the shield body (3) includes a synchrotron chamber (31) and a rotating gantry chamber ( 32), the synchrotron chamber (31) and the rotating frame chamber (32) communicate with each other;
    其中,所述旋转机架室(32)包括上旋转机架室(321)、下旋转机架室(322)及开设于所述上旋转机架室(321)和所述下旋转机架室(322)之间的机架槽(323),所述上旋转机架室(321)位于所述下旋转机架室(322)的上部,所述上旋转机架室(321)设置为与所述同步加速器室(31)相互连通并形成一个腔室。Wherein, the rotating rack chamber (32) includes an upper rotating rack chamber (321), a lower rotating rack chamber (322), and the upper rotating rack chamber (321) and the lower rotating rack chamber (322) between the frame slots (323), the upper rotating frame chamber (321) is located on the upper part of the lower rotating frame chamber (322), and the upper rotating frame chamber (321) is arranged to The synchrotron chambers (31) communicate with each other and form a chamber.
  2. 根据权利要求1所述的屏蔽体,还包括治疗室(33),所述上旋转机架室(321)与所述治疗室(33)之间设有隔离墙。The shield body according to claim 1, further comprising a treatment room (33), and a partition wall is provided between the upper rotating gantry room (321) and the treatment room (33).
  3. 根据权利要求2所述的屏蔽体,还包括迷宫室(34),所述迷宫室(34)设置于所述上旋转机架室(321)的一侧,并与所述治疗室(33)相互连通;The shield body according to claim 2, further comprising a labyrinth chamber (34), the labyrinth chamber (34) is disposed on one side of the upper rotating gantry chamber (321), and is connected to the treatment chamber (33) Interconnected
    所述迷宫室(34)设有迷宫进口和迷宫出口,所述迷宫进口与外界连通,所述迷宫出口与所述治疗室(33)相互连通。The labyrinth chamber (34) is provided with a labyrinth entrance and a labyrinth exit, the labyrinth entrance is communicated with the outside world, and the labyrinth exit is communicated with the treatment room (33).
  4. 根据权利要求3所述的屏蔽体,还包括设备室(35),所述设备室(34)与所述下旋转机架室(322)相互连通。The shield body according to claim 3, further comprising an equipment room (35), the equipment room (34) and the lower rotating rack room (322) are in communication with each other.
  5. 根据权利要求4所述的屏蔽体,其中,所述屏蔽墙为混凝土层(4)结构。The shield body according to claim 4, wherein the shield wall is a concrete layer (4) structure.
  6. 根据权利要求5所述的屏蔽体,其中,所述混凝土层(4)的厚度范围为0.5m-3.5m。The shielding body according to claim 5, wherein the thickness of the concrete layer (4) ranges from 0.5m to 3.5m.
  7. 根据权利要求4所述的屏蔽体,其中,所述屏蔽墙为复合屏蔽墙结构,所述复合屏蔽墙包括混凝土层(4)和包覆于混凝土层(4)上的铁材料层(5)。The shielding body according to claim 4, wherein the shielding wall is a composite shielding wall structure, the composite shielding wall includes a concrete layer (4) and an iron material layer (5) coated on the concrete layer (4) .
  8. 根据权利要求7所述的屏蔽体,其中,所述混凝土层(4)的厚度范围为0.5m-3m。The shielding body according to claim 7, wherein the thickness of the concrete layer (4) ranges from 0.5m to 3m.
  9. 根据权利要求8所述的屏蔽体,其中,所述铁材料层(5)的厚度范围为15cm-120cm。The shield according to claim 8, wherein the thickness of the iron material layer (5) ranges from 15 cm to 120 cm.
  10. 根据权利要求9所述的屏蔽体,其中,所述旋转机架室(32)的所述铁材料层(5)的厚度值大于所述同步加速器室(31)的所述铁材料层(5)的厚度值。The shield body according to claim 9, wherein the thickness value of the iron material layer (5) of the rotating gantry chamber (32) is greater than the iron material layer (5) of the synchrotron chamber (31) ) Thickness value.
PCT/CN2019/073198 2018-11-07 2019-01-25 Shielding apparatus for proton therapy system WO2020093608A1 (en)

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CN201821825482.4 2018-11-07
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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005120640A1 (en) * 2004-06-09 2005-12-22 Rhön-Klinikum AG Irradiation apparatus
US20080203323A1 (en) * 2005-07-22 2008-08-28 Gesellschaft Fuer Schwerionenforschung Mbh Irradiation Device
CN102049103A (en) * 2009-10-29 2011-05-11 住友重机械工业株式会社 Accelerated particle irradiation equipment and structure of storage chamber
CN102049104A (en) * 2009-10-29 2011-05-11 住友重机械工业株式会社 Accelerated particle irradiation equipment
CN103957996A (en) * 2012-01-16 2014-07-30 住友重机械工业株式会社 Charged particle beam illumination system
CN104221093A (en) * 2012-03-29 2014-12-17 三菱电机株式会社 Rotating gantry and particle beam therapy device
CN106975161A (en) * 2010-03-09 2017-07-25 住友重机械工业株式会社 Accelerated particle irradiation apparatus
CN107952178A (en) * 2017-12-13 2018-04-24 合肥中科离子医学技术装备有限公司 A kind of Proton therapy system using removable shield door compact layout
CN109200491A (en) * 2018-11-07 2019-01-15 新瑞阳光粒子医疗装备(无锡)有限公司 Shield for Proton therapy system

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005120640A1 (en) * 2004-06-09 2005-12-22 Rhön-Klinikum AG Irradiation apparatus
US20080203323A1 (en) * 2005-07-22 2008-08-28 Gesellschaft Fuer Schwerionenforschung Mbh Irradiation Device
CN102049103A (en) * 2009-10-29 2011-05-11 住友重机械工业株式会社 Accelerated particle irradiation equipment and structure of storage chamber
CN102049104A (en) * 2009-10-29 2011-05-11 住友重机械工业株式会社 Accelerated particle irradiation equipment
CN106975161A (en) * 2010-03-09 2017-07-25 住友重机械工业株式会社 Accelerated particle irradiation apparatus
CN103957996A (en) * 2012-01-16 2014-07-30 住友重机械工业株式会社 Charged particle beam illumination system
CN104221093A (en) * 2012-03-29 2014-12-17 三菱电机株式会社 Rotating gantry and particle beam therapy device
CN107952178A (en) * 2017-12-13 2018-04-24 合肥中科离子医学技术装备有限公司 A kind of Proton therapy system using removable shield door compact layout
CN109200491A (en) * 2018-11-07 2019-01-15 新瑞阳光粒子医疗装备(无锡)有限公司 Shield for Proton therapy system

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