WO2020092469A3 - Multifunctional neural probes with tunable stiffness and method of use - Google Patents

Multifunctional neural probes with tunable stiffness and method of use Download PDF

Info

Publication number
WO2020092469A3
WO2020092469A3 PCT/US2019/058715 US2019058715W WO2020092469A3 WO 2020092469 A3 WO2020092469 A3 WO 2020092469A3 US 2019058715 W US2019058715 W US 2019058715W WO 2020092469 A3 WO2020092469 A3 WO 2020092469A3
Authority
WO
WIPO (PCT)
Prior art keywords
probe
multifunctional
multifunctional neural
terminal
electrode
Prior art date
Application number
PCT/US2019/058715
Other languages
French (fr)
Other versions
WO2020092469A2 (en
Inventor
Ximiao WEN
Pei-Yu Chiou
Nigel Maidment
Bo Wang
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of WO2020092469A2 publication Critical patent/WO2020092469A2/en
Publication of WO2020092469A3 publication Critical patent/WO2020092469A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

A flexible multifunctional neural probe having distal and proximal ends includes a flexible body, at least one electrode positioned near the distal end of the probe, at least one terminal positioned near the proximal end of the probe, wherein the body is constructed from at least one flexible layer, the at least one flexible layer comprising at least one electrical channel fluidly connected to the at least one electrode and the at least one terminal, and a quantity of conductive material positioned in the at least one electrical channel, electrically connecting the at least one electrode to the at least one terminal. A method of fabricating a multifunctional neural probe and a method of implanting a multifunctional neural probe are also described.
PCT/US2019/058715 2018-10-30 2019-10-30 Multifunctional neural probes with tunable stiffness and method of use WO2020092469A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862752803P 2018-10-30 2018-10-30
US62/752,803 2018-10-30

Publications (2)

Publication Number Publication Date
WO2020092469A2 WO2020092469A2 (en) 2020-05-07
WO2020092469A3 true WO2020092469A3 (en) 2020-07-30

Family

ID=70461976

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2019/058715 WO2020092469A2 (en) 2018-10-30 2019-10-30 Multifunctional neural probes with tunable stiffness and method of use

Country Status (1)

Country Link
WO (1) WO2020092469A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111938626A (en) * 2020-08-10 2020-11-17 中国科学院上海微系统与信息技术研究所 Flexible implantable nerve photoelectric electrode and preparation method thereof
US20240001096A1 (en) * 2020-11-18 2024-01-04 University Of Florida Research Foundation, Incorporated Multifunction microfluidic optrode
CN113047045B (en) * 2021-03-29 2022-05-10 中国科学院深圳先进技术研究院 Flexible optical fiber and preparation method and application thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140107446A1 (en) * 2012-10-12 2014-04-17 Vanessa Tolosa Flexible microelectrode array with integrated stiffening shank, and method of fabrication
US9586040B2 (en) * 2012-05-18 2017-03-07 Lawrence Livermore National Security, Llc Vacuum-actuated percutaneous insertion/implantation tool for flexible neural probes and interfaces
WO2018103828A1 (en) * 2016-12-06 2018-06-14 Ecole Polytechnique Federale De Lausanne (Epfl) Implantable electrode and method for manufacturing
US20180193663A1 (en) * 2017-01-11 2018-07-12 International Business Machines Corporation Probe for localized neural optogenetics stimulation and neurochemistry recordings

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9586040B2 (en) * 2012-05-18 2017-03-07 Lawrence Livermore National Security, Llc Vacuum-actuated percutaneous insertion/implantation tool for flexible neural probes and interfaces
US20140107446A1 (en) * 2012-10-12 2014-04-17 Vanessa Tolosa Flexible microelectrode array with integrated stiffening shank, and method of fabrication
WO2018103828A1 (en) * 2016-12-06 2018-06-14 Ecole Polytechnique Federale De Lausanne (Epfl) Implantable electrode and method for manufacturing
US20180193663A1 (en) * 2017-01-11 2018-07-12 International Business Machines Corporation Probe for localized neural optogenetics stimulation and neurochemistry recordings

Also Published As

Publication number Publication date
WO2020092469A2 (en) 2020-05-07

Similar Documents

Publication Publication Date Title
WO2020092469A3 (en) Multifunctional neural probes with tunable stiffness and method of use
RU2017113694A (en) IRRIGATED BALLET CATHETER HAVING AN ELECTRODE ASSEMBLY WITH FLEXIBLE DIAGRAM
US3367339A (en) Implantable nerve stimulating electrode and lead
RU2015156052A (en) CATTETER WITH IRRIGATED POINT ELECTRODE WITH POROUS SUBSTRATE AND HIGH DENSITY SURFACE MICROELECTRODES
JP2010505550A5 (en)
JP2019063546A5 (en)
CA2797130A1 (en) Low profile electrode assembly
EP1728462A3 (en) Instrument for endoscope and instrument system for endoscope
CN102711673B (en) Liner having an integrated electrode
ATE507870T1 (en) TRANSSEPTAL/TRANSMYOCARDIAL VENTRICULAR PACING LEAD
WO2004067086A3 (en) Medical electrical lead employing load bearing sleeve
WO2006105066A3 (en) Medical electrical lead with co-radial multi-conductor coil
ATE494037T1 (en) NEURAL ELECTRODE
JP2015513980A5 (en)
WO2019027826A3 (en) Steerable medical device and the preparing method thereof
GB1495162A (en) Surgical electrode
JPH0226990B2 (en)
IL294498A (en) Biased electrodes for improved tissue contact and current delivery
WO2012103201A3 (en) Systems and methods for making and using electrical stimulation systems with improved rf compatibility
WO2008025078A8 (en) Flexible electrode assembly and apparatus for measuring electrophysiological signals
CN105536141B (en) A kind of embedded nerve stimulator electrode cable contact structure
MX2021012118A (en) Device for electrotherapy and/or electrophysiology, kit and assembly.
WO2020102754A3 (en) Nasal neurostimulation device with electrically conductive plastic electrode
US8774892B2 (en) Electrode configuration and measuring device for measuring the electrical activity in electrically active tissue
WO2012170854A3 (en) Systems and methods for customizing stimulation using implantable electrical stimulation systems

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19879755

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 19879755

Country of ref document: EP

Kind code of ref document: A2