WO2020076627A1 - Device including ultrasound, auscultation, and ambient noise sensors - Google Patents
Device including ultrasound, auscultation, and ambient noise sensors Download PDFInfo
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- WO2020076627A1 WO2020076627A1 PCT/US2019/054677 US2019054677W WO2020076627A1 WO 2020076627 A1 WO2020076627 A1 WO 2020076627A1 US 2019054677 W US2019054677 W US 2019054677W WO 2020076627 A1 WO2020076627 A1 WO 2020076627A1
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- sensor
- auscultation
- ultrasound
- ambient noise
- housing
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- G10K11/175—Methods or devices for protecting against, or for damping, noise or other acoustic waves in general using interference effects; Masking sound
Definitions
- the present application pertains to physiological sensing devices, systems and methods, and more particularly to such devices, systems and methods for acquiring ultrasound, electrocardiography, and auscultation data.
- Ultrasound imaging is typically performed in a clinical setting, by trained ultrasound experts, utilizing ultrasound systems that are specifically designed to acquire ultrasound data.
- electrocardiography EKG
- Auscultation data is typically acquired by a physician or other clinician utilizing a stethoscope.
- the signals acquired by a stethoscope may include ambient noise that is sensed by the stethoscope, in addition to the target sounds (e.g., the auscultation signals) that are sensed by the stethoscope.
- ambient noise may vary depending on a variety of factors, such as the environment in which the stethoscope is used, and may include noises generated by other electronic equipment in the environment, noises generated by the user’s hand, or the like.
- the present disclosure provides devices and methods in which ambient noise detected by an ambient noise sensor can be canceled from auscultation sounds detected by one or more auscultation sensors.
- the devices may include an ultrasound sensor and an EKG sensor, in addition to the ambient noise sensor and the auscultation sensors. Such devices may simultaneously acquire ultrasound, electrocardiography, and auscultation signals, which in some embodiments, may be synchronized with one another.
- a device in an embodiment, includes a housing having a sensor portion at a distal end of the housing, and a handle portion between a proximal end and the distal end of the housing.
- An ultrasound sensor is positioned at least partially within the sensor portion of the housing, and a first auscultation sensor is positioned at least partially within the sensor portion of the housing.
- An ambient noise sensor is positioned at least partially within the housing between the handle portion and the proximal end of the housing.
- an ultrasound probe in another embodiment, includes an ultrasound sensor, an electrocardiogram (EKG) sensor, a first auscultation sensor, an ambient noise sensor, and a processor.
- the processor is communicatively coupled to the auscultation sensor and the ambient noise sensor. In use, the processor receives an auscultation signal sensed by the first auscultation sensor and an ambient noise signal sensed by the ambient noise sensor, and generates a noise-canceled auscultation signal in which the ambient noise signal is canceled from the auscultation signal.
- the present disclosure provides a method that includes: detecting ultrasound signals by an ultrasound sensor positioned adjacent to a sensing surface of a handheld device; detecting auscultation signals by at least one auscultation sensor positioned adjacent to the sensing surface of the handheld device; detecting ambient noise signals by an ambient noise sensor positioned between a handle portion of the handheld device and a proximal end of the handheld device, the ambient noise sensor being spaced apart from the sensor surface by at least the handle portion; and generating a noise-canceled auscultation signal by canceling the ambient noise signal from the auscultation signal.
- Figure 1 is a perspective view illustrating a device having an ultrasound sensor, an auscultation sensor, and an ambient noise sensor, in accordance with one or more embodiments of the present disclosure.
- Figure 2 is an enlarged perspective view of a sensor portion of the device shown in Figure 1 , in accordance with one or more embodiments.
- Figure 3 is a cross-sectional view taken along the cut-line 3-3 of Figure 2, illustrating further details of the sensing portion of the device, in accordance with one or more embodiments.
- Figure 4 is a cross-sectional view taken along the cut-line 4-4 of Figure 2, illustrating further details of the sensing portion of the device, in accordance with one or more embodiments.
- Figure 5 is a cross-sectional view taken along the cut-line 5-5 of Figure 1 , illustrating further details of the device, in accordance with one or more embodiments.
- Figure 6 is an enlarged cross-sectional view showing further details of an ambient noise sensor of the device, in accordance with one or more embodiments.
- ultrasound imaging has been one of the most effective methods for examining both the heart and the lungs.
- Ultrasound imaging provides anatomical information of the heart as well as qualitative and quantitative information on blood flow through valves and main arteries such as the aorta and pulmonary artery.
- One significant advantage of ultrasound imaging is that, with its high frame rate, it can provide dynamic anatomical and blood flow information which is vital for assessing the condition of the heart which is always in motion.
- ultrasound imaging provides one of the best available tools for assessing the structure and function of heart chambers, valves, and arteries/veins. Similarly, ultrasound imaging can assess fluid status in the body and is the best tool in assessing pericardial effusion (fluid around the heart).
- ultrasound imaging provides information on the anatomical structure of the lungs with the ability to show specific imaging patterns associated with various lung diseases and with an ability to assess fluid status around the lung and within individual compartments of the lung including the assessment of pericardial effusion.
- Auscultation allows for assessing the physiological condition and function of organs such as the heart and lungs by capturing audible sounds that are produced by or otherwise associated with these organs.
- the condition and function of these organs, or other organs as the case may be, can be evaluated based on clinical information indicating how different sounds are associated with various physiological phenomena and how the sounds change for each pathological condition.
- Electrocardiography is focused on the heart by capturing the electrical activity of the heart as it is related to the various phases of the cardiac cycle.
- the condition and function of the heart may be evaluated based on clinical knowledge indicating how the electrical activity of the heart changes based on various pathological conditions.
- the present disclosure provides devices and methods in which auscultation, EKG, and ultrasound signals may be acquired by a single handheld device.
- the handheld device may acquire ambient noise signals by an ambient noise sensor that is spaced apart from the auscultation, EKG, and ultrasound sensors. The ambient noise may be canceled or subtracted from the auscultation signals, thereby producing a clear auscultation signal which is more useful, for example, to a physician or user of the handheld device.
- Figure 1 is a perspective view illustrating a device 100, which is operable to acquire ultrasound, electrocardiographic, and auscultation signals, in accordance with embodiments of the present disclosure.
- the device 100 includes a housing 110, which forms an external portion of the device 100.
- the housing 110 includes a sensor portion 112 near a distal end 115 of the housing 110, and a handle portion 114 between a proximal end 113 and the distal end 115 of the housing 110.
- the handle portion 114 is proximally located with respect to the sensor portion 112.
- the handle portion 114 is a portion of the housing 110 that is gripped by a user to hold, control, and manipulate the device 100 during use.
- the handle portion 114 may include gripping features, such as one or more detents 117, and in some embodiments, the handle portion 114 may have a same general shape as portions of the housing 110 that are distal to, or proximal to, the handle portion 114.
- the handle portion 114 refers to a portion of the housing 110 that is located between the sensor portion 112 and an ambient noise sensor 138, which will be described in further detail later herein.
- the housing 110 surrounds internal electronic components and/or circuitry of the device 100, including, for example, electronics such as driving circuitry, processing circuitry, oscillators, beamforming circuitry, filtering circuitry, and the like.
- the housing 110 may be formed to surround or at least partially surround externally located portions of the device 100, such as a sensor face 120, and may a sealed housing, such that moisture, liquid or other fluids are prevented from entering the housing 110.
- the housing 110 may be formed of any suitable materials, and in some embodiments, the housing 110 is formed of a plastic material.
- the housing 110 may be formed of a single piece (e.g., a single material that is molded surrounding the internal components) or may be formed of two or more pieces (e.g., upper and lower halves) which are bonded or otherwise attached to one another.
- FIG. 2 is an enlarged perspective view of the sensor portion of the device shown in Figure 1.
- the sensor portion 112 of the device 100 includes an ultrasound sensor 132, and at least one auscultation sensor 134.
- the sensor portion 112 includes an electrocardiogram (EKG) sensor 136, which may include a plurality of EKG leads or electrodes 136a, 136b, 136c.
- EKG electrocardiogram
- the sensor face 120 may be placed in contact with a patient’s skin, and the device 100 may obtain ultrasound, auscultation, and EKG signals via the ultrasound sensor 132, the at least one auscultation sensor 134, and the EKG sensor 136, respectively.
- the device 100 includes two auscultation sensors 134 adjacent to the sensor face 120.
- the auscultation sensors 134 may be any sensor operable to detect internal body sounds of a patient, including, for example, body sounds associated with the circulatory, respiratory, and gastrointestinal systems.
- the auscultation sensors 134 may be microphones.
- the auscultation sensors 134 may be electronic or digital stethoscopes, and may include or otherwise be electrically coupled to amplification and signal processing circuitry for amplifying and processing sensed signals, as may be known in the relevant field.
- the device 100 further includes an ambient noise sensor 138 positioned at least partially within the housing between the handle portion 114 and the proximal end 113 of the housing 110.
- the ambient noise sensor 138 may be any microphone suitable to detect ambient sounds.
- the ambient noise sensor 138 senses ambient sounds, and a noise-canceled signal may be generated in which the ambient sounds are canceled from the target sounds (e.g., heart sounds of a patient) that are sensed by the auscultation sensors 134.
- the ambient sounds that are sensed by the ambient noise sensor 138 may be, for example, sounds generated by electronic equipment, sounds generated by the ultrasound sensor 132 (e.g., by an ultrasound array), sounds generated by a user of the device 100, such as by movement of the user’s hands, or any other sounds that may be present in an environment in which the device 100 is used.
- the ultrasound sensor 132 includes an ultrasound array or transducer 142 ( Figure 3) configured to transmit an ultrasound signal toward a target structure in a region of interest in the patient.
- the transducer 142 is further configured to receive echo signals returning from the target structure in response to transmission of the ultrasound signal.
- the transducer 142 may include transducer elements that are capable of transmitting an ultrasound signal and receiving subsequent echo signals.
- the transducer elements may be arranged as elements of a phased array. Suitable phased array transducers are known in the art.
- the transducer 142 of the ultrasound sensor 132 may be a one- dimensional (1 D) array or a two-dimensional (2D) array of transducer elements.
- the transducer array may include piezoelectric ceramics, such as lead zirconate titanate (PZT), or may be based on microelectromechanical systems (MEMS).
- PZT lead zirconate titanate
- MEMS microelectromechanical systems
- the ultrasound sensor 132 may include piezoelectric micromachined ultrasonic transducers (PMUT), which are microelectromechanical systems (MEMS)-based piezoelectric ultrasonic transducers, or the ultrasound sensor 132 may include capacitive
- CMUT micromachined ultrasound transducers
- the ultrasound sensor 132 may further include an ultrasound focusing lens 144, which is positioned distally with respect to the ultrasound transducer 142, and which may form a part of the sensor face 120.
- the focusing lens 144 may be any lens operable to focus a transmitted ultrasound beam from the ultrasound transducer 142 toward a patient and/or to focus a reflected ultrasound beam from the patient to the transducer 142.
- the ultrasound focusing lens 144 may have a curved surface shape in some embodiments.
- the ultrasound focusing lens 144 may have different shapes, depending on a desired application, e.g., a desired operating frequency, or the like.
- the ultrasound focusing lens 144 may be formed of any suitable material, and in some embodiments, the ultrasound focusing lens 144 is formed of a room-temperature-vulcanizing (RTV) rubber material.
- RTV room-temperature-vulcanizing
- the EKG sensor 136 may be any sensor that detects electrical activity, e.g., of a patient’s heart, as may be known in the relevant field.
- the EKG sensor 136 may include any number of electrodes 136a, 136b, 136c, which in operation are placed in contact with a patient’s skin and are used to detect electrical changes in the patient that are due to the heart muscle’s pattern of depolarizing and repolarizing during each heartbeat.
- the EKG sensor 136 may include a first electrode 136a that is positioned adjacent to a first side of the ultrasound sensor 132 (e.g., adjacent to the left side of the ultrasound focusing lens 144, as shown), and a second electrode 136b that is positioned adjacent to a second side of the ultrasound sensor 132 that is opposite to the first side (e.g., adjacent to the right side of the ultrasound focusing lens 144, as shown).
- the EKG sensor 136 may further include a third electrode 136c that is positioned adjacent to a third side of the ultrasound sensor 132 (e.g., adjacent to the lower side of the ultrasound focusing lens 144, as shown).
- each of the first, second, and third electrodes 136a, 136b, 136c have different polarities.
- the first electrode 136a may be a positive (+) electrode
- the second electrode 136b may be a negative (-) electrode
- the third electrode 136c may be a ground electrode.
- the number and positions of the EKG sensor electrodes may vary in different embodiments. As shown in Figure 2, the electrodes 136a, 136b, 136c may be approximately equidistant from one another. The first and second electrodes 136a, 136b may be positioned near a top edge of the distal end 115 of the housing 110, while the third electrode 136c may be positioned between the lower side of the ultrasound sensor 132 and a bottom edge of the distal end 115 of the housing 110.
- first and second membranes 152, 154 are positioned adjacent to opposite sides of the ultrasound sensor 132 and may form a part of the sensor face 120.
- the membranes 152, 154 may be formed of any suitable material, and in some embodiments, the membranes 152, 154 are formed of a room-temperature-vulcanizing (RTV) rubber material. In some embodiments, the membranes 152, 154 are formed of a same material as the ultrasound focusing lens 144.
- RTV room-temperature-vulcanizing
- the sensor face 120 includes a sealant which seals the sensor face 120 of the device 100 so that it is compliant with ingress protection specifications of IPX7 of the IP Code (as published by the International Electrotechnical Commission) (e.g., it is liquid tight when submerged to a depth of at least one meter).
- the sealant may be provided, for example, between the membranes 152, 154 and the respective sides of the ultrasound sensor 132, and/or between the ultrasound sensor 132, the membranes 152, 154 and the side surfaces of the distal end 115 of the housing 110.
- the sealant is provided over the ultrasound focusing lens 144 of the ultrasound sensor 132 and the membranes 152, 154.
- the sealant may be a RTV rubber material, and in some embodiments, the sealant may be formed of a same material as the ultrasound focusing lens 144 and/or the membranes 152, 154.
- the membranes 152, 154 are positioned in front of (i.e. , distally with respect to) the auscultation sensors 134.
- the auscultation sensors 134 are spaced apart from the membranes 152, 154 by respective gaps 156, which may be air gaps.
- the auscultation sensors 134 may be positioned in respective auscultation sensor sockets 158, which may fix a position of the auscultation sensors 134 so that they are spaced apart from the respective membranes 152, 154 by a desired gap 156.
- the auscultation sensor sockets 158 are formed as an internal piece of the housing 110.
- the auscultation sensor sockets 158 may be molded into the housing 110.
- the auscultation sensor sockets 158 may be sized to accommodate the
- auscultation sensors 134 and the auscultation sensors 134 may be securely held in the auscultation sensor sockets 158. In some embodiments, the auscultation sensors 134 may be secured within the auscultation sensor sockets 158 by an adhesive material.
- the auscultation sensor sockets 158 may include distal flanges 159 which impede movement of the auscultation sensors 134 in the distal direction. That is, the distal flanges 159 may have a dimension that is smaller than a perimeter dimension of the auscultation sensors 134, so that the auscultation sensors 134 cannot fit through the distal flanges 159. Instead, the auscultation sensors 134 may be fixed in a position (e.g., in abutting contact) by the distal flanges 159 of the auscultation sensor sockets 158.
- the distal flanges 159 may have a thickness which defines the distance of the gaps 156.
- the distal flanges 159 may extend between surfaces of the auscultation sensors 134 and respective surfaces of the first and second membranes 152, 154, and the openings within the distal flanges 159 may define the distance of gaps 156.
- the gaps 156 has a distance within a range of about 0.5 mm to about 1.5 mm, inclusive. In some embodiments, the gaps 156 have a distance of about 1 mm.
- the membranes 152, 154 may operate as diaphragms which convert mechanical vibrations (e.g., from motion against the membranes 152, 154 and/or in response to receiving acoustic vibrations) into sounds which are detectable by the auscultation sensors 134.
- Figure 4 is a cross-sectional view taken along the cut-line 4-4 of Figure 2, illustrating further details of the sensing portion of the device, in accordance with one or more embodiments.
- Figure 4 illustrates further details of the first and second EKG sensor electrodes 136a, 136b.
- the first and second electrodes 136a, 136b may be positioned in respective EKG electrode sockets 168, which may hold the electrodes 136a, 136b in a desired position.
- the EKG electrode sockets 168 are formed as an internal piece of the housing 110, and may be molded into the housing 110.
- the EKG electrode sockets 168 may be sized to accommodate the electrodes 136a, 136b, and the electrodes 136a, 136b may be securely held in the EKG electrode sockets 168.
- the electrodes 136a, 136b may be secured within the EKG electrode sockets 168 by an adhesive material.
- the third electrode 136c may be held in a desired position along the sensor face 120 by a same or similar EKG electrode socket 168 that is sized to accommodate the third electrode 136c.
- the EKG electrode sockets 168 may include proximal flanges 169 which impede movement of the electrodes 136a, 136b in the proximal direction. That is, the proximal flanges 169 may have a dimension that is smaller than a perimeter dimension of the electrodes 136a, 136b, so that the electrodes 136a, 136b cannot fit through the proximal flanges 169.
- the electrodes 136a, 136b may extend through the membranes 152, 154 so that the electrodes 136a, 136b are exposed along the sensor face 120.
- the first electrode 136a may extend through the first membrane 152
- the second electrode 136b may extend through the second membrane 154.
- the third electrode 136c may be exposed along the sensor face 120.
- the membranes 152, 154 may have openings through which the electrodes 136a, 136b may extend, and the membranes 152, 154 may contact side surfaces of the electrodes 136a, 136b so that the electrodes 136a, 136b are substantially sealed along the sensor face 120.
- a sealant which may be a RTV rubber material, may be provided between the membranes 152, 154 and the electrodes 136a, 136b and the sealant may be formed of a same material as the ultrasound focusing lens 144 and/or the membranes 152, 154.
- EKG leads or wires 172 are attached to the electrodes 136a,
- 136b, 136c may electrically couple the electrodes 136a, 136b, 136c to processing circuitry.
- Figure 5 is a cross-sectional view taken along the cut-line 5-5 of Figure 1 , illustrating further details of the device 100, in accordance with one or more embodiments.
- Figure 6 is an enlarged cross-sectional view of a region 6 of Figure 5, showing further details of an ambient noise sensor of the device 100 in accordance with one or more embodiments.
- the device 100 may include an internal board 180, and various circuitry and components may be attached to the board 180.
- the internal board 180 may be any structure suitable to hold or carry the various circuitry and components included within the housing 110.
- the internal board 180 is a printed circuit board (PCB) and may include wires, conductive traces, conductive vias, or the like for electrically coupling one or more circuits or components of the device 100 to each other.
- the internal board 180 may be coupled to the housing 110 by any suitable technique.
- one or more threaded receptacles 181 are attached to or otherwise formed as part of the housing 110, and the internal board 180 may be coupled to the housing 110 by one or more threaded fasteners 182, such as screws, which are threaded into the threaded
- the ambient noise sensor 138 may be positioned in an ambient noise sensor socket 178, which may fix a position of the ambient noise sensor 138.
- the ambient noise sensor socket 178 may be substantially similar to the auscultation sensor sockets 158 shown in Figure 3, except that the ambient noise sensor socket 178 may be oriented in a direction (e.g., vertical direction as shown) that is transverse to the direction in which the auscultation sensor sockets are oriented (e.g., horizontal direction).
- An ambient noise sensor membrane 174 is positioned over the ambient noise sensor 138 and may form an external portion of the device 100. That is, the ambient noise sensor membrane 174 may be exposed to the external environment.
- the ambient noise sensor membrane 174 may be formed of any suitable material, and in some embodiments, the ambient noise sensor membrane 174 is formed of a room-temperature-vulcanizing (RTV) rubber material. In some embodiments, the ambient noise sensor membrane 174 may be formed of a same material as the first and second membranes 152, 154 and/or the ultrasound focusing lens 144. The ambient noise sensor membrane 174 may have any shape, and in some embodiments, the ambient noise sensor membrane 174 has a substantially circular shape in top plan view. In some embodiments, the ambient noise sensor membrane 174 may have a diameter of about 10mm, and may have a thickness of about 2mm.
- RTV room-temperature-vulcanizing
- the ambient noise sensor 138 may be positioned in the ambient noise sensor socket 178, which may fix a position of the ambient noise sensor 138 so that it is spaced apart from the ambient noise sensor membrane 174 by a desired gap 176, which may be an air gap.
- the ambient noise sensor socket 178 is formed as an internal piece of the housing 110, for example, the ambient noise sensor socket 178 may be molded into the housing 110.
- the ambient noise sensor 138 may be secured within the ambient noise sensor socket 178 by an adhesive material, such as glue or any other adhesive.
- One or more slots or grooves 175 may be included in the housing 110 and positioned adjacent to the ambient noise sensor socket 178.
- the grooves 175 are configured to accommodate excess adhesive materials which may be used to attach the ambient noise sensor 138 to the ambient noise sensor socket 178.
- the ambient noise sensor socket 178 may include a flange 179 which impedes movement of the ambient noise sensor 138 and fixes a position of the ambient noise sensor 138 with respect to the ambient noise sensor socket 178.
- the flange 179 may be substantially similar to the distal flanges 159 of the auscultation sensor sockets 158, and may have a thickness which defines the distance of the gap 176.
- the gap 176 between the ambient noise sensor 138 and the ambient noise sensor membrane 174 has a distance within a range of about 0.5 mm to about 1.5 mm, inclusive.
- the gap 176 has a distance of about 1 mm.
- the gap 176 has a distance that is substantially the same as a distance of the gaps 156 between the auscultation sensors 134 and the membranes 152, 154.
- the ambient noise sensor socket 178 and/or the ambient noise sensor membrane 174 may be omitted.
- the ambient noise sensor 138 may be mounted at any suitable position within the housing 110, including rigidly mounted on the inside of the housing 110. Alternatively or additionally, the ambient noise sensor 138 may be mounted without the ambient noise sensor membrane 174. In some embodiments, the ambient noise sensor 138 may be mounted directly on the internal board 180, which may be a PCB as previously described herein.
- the device 100 may include a variety of different electrical components, circuitry, and the like.
- the device 100 may include processing circuitry 185 which may communicatively coupled (e.g., by one or more wires, by a wireless communication path, or the like) to the auscultation sensors 134 and to the ambient noise sensor 138.
- the processing circuitry 185 may be implemented at least in part as software that is loadable or executable by one or more hardware structures, such as a microcontroller, microprocessor, or the like.
- the processing circuitry 185 is configured to receive an
- the processing circuitry 185 may generate the noise- canceled auscultation signal by any suitable techniques. In some
- the processing circuitry 185 may generate a cancelation waveform that is a negative of the ambient noise signal sensed by the ambient noise sensor 138, and may mix the cancelation waveform with the auscultation signal sensed by the auscultation sensors 134 in order to produce the noise- canceled auscultation signal.
- the processing circuitry 185 may further include or otherwise be coupled to audio processing circuitry for processing the signals received from the auscultation sensors 134 and the ambient noise sensor 138, including, for example, filters, amplifiers, preconditioning and digitization circuitry, and the like.
- the device 100 may further include EKG signal processing circuitry, ultrasound processing and/or driving circuitry or any other circuitry that may be utilized during operation of the device 100 and which may facilitate operations of the device 100 as described herein.
- processing and/or driving circuitry may be positioned on the internal board 180 and may be coupled to the processing circuitry 185. In some embodiments, such
- processing and/or driving circuitry may be included at least partially in the processing circuitry 185.
- the device 100 may further include one or more computer- readable memories, which may be any computer-readable storage medium, including, for example, read-only memory (ROM), random access memory (RAM), flash memory, hard disk drive, optical storage device, magnetic storage device, electrically erasable programmable read-only memory (EEPROM), organic storage media, or the like.
- the computer-readable memory may be coupled to the processing circuitry 185, and in some embodiments the memory may store the various signals acquired by the device 100. The signals may be stored in the memory in a synchronized manner, or with associated information for synchronizing the signals.
- a user may place the sensor face 120 of the device 100 in a desired location on a patient’s body.
- the device 100 receives signals from the auscultation sensors 134, the EKG sensor 136, and the ultrasound sensor 132 at the sensor face 120.
- device 100 receives ambient noise signals from the ambient noise sensor 138, and generates a noise-canceled auscultation signal based on the auscultation signals received from the auscultation sensors 134 and the ambient noise signals received from the ambient noise sensor 138.
- the signals acquired from one or more of the auscultation sensors 134, the EKG sensor 136, the ultrasound sensor 132, and the ambient noise sensor 138 may be simultaneously acquired and synchronized with one another.
- the auscultation sensors 134, the EKG sensor 136, the ultrasound sensor 132, and the ambient noise sensor 138 may be simultaneously acquired and synchronized with one another.
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Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
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KR1020217013825A KR20210106982A (en) | 2018-10-08 | 2019-10-04 | DEVICE INCLUDING ULTRASOUND, AUSCULTATION, AND AMBIENT NOISE SENSORS |
CN201980076255.7A CN113056234A (en) | 2018-10-08 | 2019-10-04 | Device comprising an ultrasound sensor, an auscultation sensor and an ambient noise sensor |
JP2021543992A JP2022508629A (en) | 2018-10-08 | 2019-10-04 | Devices including ultrasonic sensors, auscultation sensors, and ambient noise sensors |
AU2019356470A AU2019356470A1 (en) | 2018-10-08 | 2019-10-04 | Device including ultrasound, auscultation, and ambient noise sensors |
EP19871815.7A EP3863521A4 (en) | 2018-10-08 | 2019-10-04 | Device including ultrasound, auscultation, and ambient noise sensors |
CA3115470A CA3115470A1 (en) | 2018-10-08 | 2019-10-04 | Device including ultrasound, auscultation, and ambient noise sensors |
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US201862742714P | 2018-10-08 | 2018-10-08 | |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021257891A1 (en) * | 2020-06-19 | 2021-12-23 | EchoNous, Inc. | Device and methods for motion artifact suppression in auscultation and ultrasound data |
JP2023539116A (en) * | 2020-08-19 | 2023-09-13 | オトネクサス メディカル テクノロジーズ, インコーポレイテッド | wearable auscultation device |
USD957649S1 (en) * | 2020-12-03 | 2022-07-12 | GE Precision Healthcare LLC | Sensor with battery |
AU2023201955B1 (en) * | 2023-03-30 | 2023-12-14 | Corsonys Pty. Ltd. | Device, method and system for detecting sound or audio waves |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005037096A1 (en) * | 2003-09-23 | 2005-04-28 | Meditron Asa | Medical diagnostic apparatus and method for measuring blood pressure |
US20050165310A1 (en) * | 2002-03-27 | 2005-07-28 | Herve Bindefeld | Apparatus for screening and diagnosing by dual stethoscopic and doppler detection |
US9078571B2 (en) * | 2005-11-15 | 2015-07-14 | Active Signal Technologies, Inc. | High sensitivity noise immune stethoscope |
US20160045183A1 (en) * | 2013-04-05 | 2016-02-18 | Samsung Electronics Co., Ltd. | Electronic stethoscope apparatus, automatic diagnostic apparatus and method |
US20160100817A1 (en) * | 2014-10-14 | 2016-04-14 | Arsil Nayyar Hussain | Systems, devices, and methods for capturing and outputting data regarding a bodily characteristic |
Family Cites Families (127)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3954098A (en) | 1975-01-31 | 1976-05-04 | Dick Donald E | Synchronized multiple image tomographic cardiography |
US4100916A (en) | 1976-04-27 | 1978-07-18 | King Donald L | Three-dimensional ultrasonic imaging of animal soft tissue |
US4154230A (en) | 1977-01-17 | 1979-05-15 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | EKG and ultrasonoscope display |
JPS6220175Y2 (en) * | 1979-11-07 | 1987-05-22 | ||
US4304240A (en) | 1980-03-07 | 1981-12-08 | The Kendall Company | Esophageal probe with dual sound detection |
FR2518751A1 (en) | 1981-12-22 | 1983-06-24 | Euratom | SYSTEM FOR MONITORING A PLURALITY OF CONTAINERS USING ULTRASONIC SEALS |
CA1199371A (en) | 1982-12-03 | 1986-01-14 | Orest Z. Roy | Ultrasonic enhancement of cardiac contractility synchronised with ecg event or defibrillation pulse |
US4572202A (en) | 1983-11-14 | 1986-02-25 | Elscint Inc. | Method and apparatus for high-speed ultrasonic imaging |
US4515164A (en) | 1984-03-23 | 1985-05-07 | Intech Systems Corp. | Differential doppler for blood flow measurement |
US5159931A (en) | 1988-11-25 | 1992-11-03 | Riccardo Pini | Apparatus for obtaining a three-dimensional reconstruction of anatomic structures through the acquisition of echographic images |
DE3914619A1 (en) | 1989-05-03 | 1990-11-08 | Kontron Elektronik | DEVICE FOR TRANSOESOPHAGEAL ECHOCARDIOGRAPHY |
US5178149A (en) | 1989-11-06 | 1993-01-12 | Michael Imburgia | Transesophageal probe having simultaneous pacing and echocardiographic capability, and method of diagnosing heart disease using same |
US5360005A (en) | 1992-01-10 | 1994-11-01 | Wilk Peter J | Medical diagnosis device for sensing cardiac activity and blood flow |
US5539831A (en) * | 1993-08-16 | 1996-07-23 | The University Of Mississippi | Active noise control stethoscope |
US5398691A (en) | 1993-09-03 | 1995-03-21 | University Of Washington | Method and apparatus for three-dimensional translumenal ultrasonic imaging |
JP3410843B2 (en) | 1994-12-27 | 2003-05-26 | 株式会社東芝 | Ultrasound diagnostic equipment |
US8241217B2 (en) | 1995-06-29 | 2012-08-14 | Teratech Corporation | Portable ultrasound imaging data |
US5749833A (en) | 1995-08-15 | 1998-05-12 | Hakki; A-Hamid | Combined echo-electrocardiographic probe |
US5812678A (en) * | 1996-02-26 | 1998-09-22 | Scalise; Stanley J. | Auscultation augmentation device |
AU2414497A (en) | 1996-04-25 | 1997-11-12 | Per Samuel Bjorgaas | Method and instrument for examination of heart/arteries |
US6962566B2 (en) | 2001-04-19 | 2005-11-08 | Sonosite, Inc. | Medical diagnostic ultrasound instrument with ECG module, authorization mechanism and methods of use |
JPH10127626A (en) | 1996-10-31 | 1998-05-19 | Hewlett Packard Co <Hp> | Ekg data display device |
US5960089A (en) | 1996-11-08 | 1999-09-28 | Nicolet Vascular, Inc. | Ultrasound bell attachment for stethoscope |
US6110120A (en) | 1997-04-11 | 2000-08-29 | Acuson Corporation | Gated ultrasound imaging apparatus and method |
US6547730B1 (en) | 1998-12-31 | 2003-04-15 | U-Systems, Inc. | Ultrasound information processing system |
US6514201B1 (en) | 1999-01-29 | 2003-02-04 | Acuson Corporation | Voice-enhanced diagnostic medical ultrasound system and review station |
US6139500A (en) | 1999-02-24 | 2000-10-31 | Agilent Technologies Inc. | Methods and apparatus for 3D cardiac ultrasound imaging |
US6213944B1 (en) | 1999-03-05 | 2001-04-10 | Atl Ultrasound, Inc. | Ultrasonic diagnostic imaging system with a digital video recorder with visual controls |
JP4377495B2 (en) | 1999-10-29 | 2009-12-02 | 株式会社東芝 | Ultrasonic diagnostic equipment |
US6454716B1 (en) | 2000-05-23 | 2002-09-24 | P.M.G. Medica Ltd. | System and method for detection of fetal heartbeat |
NZ523691A (en) | 2000-06-23 | 2004-05-28 | Meditron As | Two-way mechano-electrical transducer |
US7914453B2 (en) | 2000-12-28 | 2011-03-29 | Ardent Sound, Inc. | Visual imaging system for ultrasonic probe |
US7450746B2 (en) | 2002-06-07 | 2008-11-11 | Verathon Inc. | System and method for cardiac imaging |
US7211045B2 (en) | 2002-07-22 | 2007-05-01 | Ep Medsystems, Inc. | Method and system for using ultrasound in cardiac diagnosis and therapy |
US7927275B2 (en) | 2002-08-26 | 2011-04-19 | The Cleveland Clinic Foundation | System and method of aquiring blood-vessel data |
US6673017B1 (en) | 2002-08-28 | 2004-01-06 | Acuson Corporation | Temporal resolution method and systems for ultrasound imaging |
TW592668B (en) | 2003-05-08 | 2004-06-21 | De-Yang Tian | Measuring device |
US8591417B2 (en) | 2003-05-20 | 2013-11-26 | Panasonic Corporation | Ultrasonic diagnostic apparatus |
US7303530B2 (en) * | 2003-05-22 | 2007-12-04 | Siemens Medical Solutions Usa, Inc. | Transducer arrays with an integrated sensor and methods of use |
ITPI20030057A1 (en) | 2003-08-08 | 2005-02-09 | Rossi Danilo De | WEARABLE DEVICE FOR SIGNAL MONITORING |
US7618371B2 (en) | 2003-08-20 | 2009-11-17 | Hansen Medical, Inc. | System and method for 3-D imaging |
US7247139B2 (en) | 2003-09-09 | 2007-07-24 | Ge Medical Systems Global Technology Company, Llc | Method and apparatus for natural voice control of an ultrasound machine |
US7300406B2 (en) | 2003-09-30 | 2007-11-27 | Carter Vandette B | Medical examination apparatus |
WO2005039418A1 (en) | 2003-10-23 | 2005-05-06 | Koninklijke Philips Electronics, N.V. | Ultrasound imaging method and apparatus |
JP2005270375A (en) * | 2004-03-25 | 2005-10-06 | Ge Medical Systems Global Technology Co Llc | Ultrasonic probe and attachment |
US20060004290A1 (en) | 2004-06-30 | 2006-01-05 | Smith Lowell S | Ultrasound transducer with additional sensors |
EP1843699A1 (en) | 2005-02-04 | 2007-10-17 | Hervé Bindefeld | Portable medical screening apparatus with triple stethoscopic, doppler and blood stream detection |
US7792314B2 (en) | 2005-04-20 | 2010-09-07 | Mitsubishi Electric Research Laboratories, Inc. | System and method for acquiring acoustic signals using doppler techniques |
US9161721B2 (en) | 2005-09-21 | 2015-10-20 | Chang-Ming Yang | Electronic device and method of using the same |
US7981038B2 (en) | 2005-10-11 | 2011-07-19 | Carnegie Mellon University | Sensor guided catheter navigation system |
US7733224B2 (en) | 2006-06-30 | 2010-06-08 | Bao Tran | Mesh network personal emergency response appliance |
US8092396B2 (en) | 2005-10-20 | 2012-01-10 | Merat Bagha | Electronic auscultation device |
WO2007051261A1 (en) * | 2005-11-07 | 2007-05-10 | Signostics Pty Ltd | Ultrasound measurement system and method |
ES2298001B1 (en) | 2005-11-12 | 2009-03-16 | Eva Torrent Lopez | SLIP WITH LUMBAR PROTECTION. |
US7697982B2 (en) | 2006-04-27 | 2010-04-13 | General Electric Company | Synchronization to a heartbeat |
US7539532B2 (en) | 2006-05-12 | 2009-05-26 | Bao Tran | Cuffless blood pressure monitoring appliance |
NZ574606A (en) | 2006-07-07 | 2010-09-30 | Signostics Pty Ltd | Improved medical interface with a slow continuous data rate and faster intermittent data rate |
NZ574865A (en) | 2006-07-17 | 2011-03-31 | Signostics Pty Ltd | Improved medical diagnostic device |
JP2008142112A (en) * | 2006-12-06 | 2008-06-26 | Konica Minolta Medical & Graphic Inc | Biological sound sensor |
US8057390B2 (en) | 2007-01-26 | 2011-11-15 | The Regents Of The University Of Michigan | High-resolution mapping of bio-electric fields |
JP4953367B2 (en) * | 2007-02-23 | 2012-06-13 | 学校法人産業医科大学 | Stethoscope accessories and stethoscope system |
GB0706285D0 (en) | 2007-03-30 | 2007-05-09 | You Care Ltd | Precordial device |
US8226562B2 (en) | 2007-08-10 | 2012-07-24 | Ultrasonix Medical Corporation | Hand-held ultrasound system having sterile enclosure |
US9561015B2 (en) | 2007-08-24 | 2017-02-07 | General Electric Company | Method and apparatus for voice recording with ultrasound imaging |
JP5156750B2 (en) | 2007-09-07 | 2013-03-06 | パナソニック株式会社 | Ultrasonic diagnostic equipment |
US8764660B2 (en) * | 2007-10-16 | 2014-07-01 | General Electric Company | Methods and apparatus for combined audible and ultrasound inspection of objects, including patients |
DE102008025674B4 (en) | 2008-05-29 | 2021-01-21 | Tom Tec Imaging Systems Gmbh | Method, device and computer program product for recording medical images of a moving object |
US9089278B2 (en) | 2008-07-10 | 2015-07-28 | Koninklijke Philips N.V. | Ultrasonic assessment of cardiac synchronicity and viability |
EP2347715A4 (en) | 2008-10-02 | 2012-10-10 | Kwang Tae Kim | Cerebrovascular analysis system |
AU2009302220B2 (en) | 2008-10-09 | 2014-03-27 | The Regents Of The University Of California | Methods, system and apparatus for the detection, diagnosis and treatment of biological rhythm disorders |
US20100286527A1 (en) | 2009-05-08 | 2010-11-11 | Penrith Corporation | Ultrasound system with multi-head wireless probe |
JP5416274B2 (en) | 2009-05-27 | 2014-02-12 | カーディアック ペースメイカーズ, インコーポレイテッド | Adaptive event memory in an implantable device |
US20100331708A1 (en) | 2009-06-29 | 2010-12-30 | Edwards Lifesciences Corporation | Monitoring cardiovascular conditions using signal transit times |
US9220440B2 (en) | 2009-09-21 | 2015-12-29 | Nellcor Puritan Bennett Ireland | Determining a characteristic respiration rate |
US20130053657A1 (en) | 2009-09-28 | 2013-02-28 | Illuminare Holdings Ltd. | Intravaginal monitoring device and network |
EP2488106B1 (en) * | 2009-10-15 | 2020-07-08 | Masimo Corporation | Acoustic respiratory monitoring sensor having multiple sensing elements |
US9414786B1 (en) | 2009-11-03 | 2016-08-16 | Vivaquant Llc | ECG sensing with noise filtering |
JP2011212043A (en) | 2010-03-31 | 2011-10-27 | Fujifilm Corp | Medical image playback device and method, as well as program |
US10238362B2 (en) | 2010-04-26 | 2019-03-26 | Gary And Mary West Health Institute | Integrated wearable device for detection of fetal heart rate and material uterine contractions with wireless communication capability |
CN103108592A (en) * | 2010-06-11 | 2013-05-15 | 卫理公会医院研究所 | Integrated, hand-held apparatus and associated method for acquiring diagnostic and prognostic information from a patient at the bedside or at some other patient location |
WO2012015093A1 (en) | 2010-07-30 | 2012-02-02 | 엘지전자 주식회사 | Method and electronic device for remote diagnosis |
CA2807240A1 (en) | 2010-08-04 | 2012-02-09 | Idexx Laboratories, Inc. | Detection of degradation products of canine nt-probnp |
CN103079472A (en) | 2010-08-31 | 2013-05-01 | 株式会社日立医疗器械 | Ultrasound diagnostic device and heart function test interval detection and display method |
US9717412B2 (en) | 2010-11-05 | 2017-08-01 | Gary And Mary West Health Institute | Wireless fetal monitoring system |
US9259160B2 (en) | 2010-12-01 | 2016-02-16 | Nellcor Puritan Bennett Ireland | Systems and methods for determining when to measure a physiological parameter |
USD675738S1 (en) | 2011-04-02 | 2013-02-05 | Inovise Medical, Inc. | Heart-sound and ECG sensor and adapter combination |
EP2706920A4 (en) | 2011-05-13 | 2014-11-05 | Parace Llc | Medical examination apparatus |
WO2013040546A1 (en) | 2011-09-16 | 2013-03-21 | University Of Pittsburgh - Of The Commonwealth | Noncontact electrophysiological measurement and imaging of the heart |
JP5972569B2 (en) | 2011-12-26 | 2016-08-17 | 東芝メディカルシステムズ株式会社 | Ultrasonic diagnostic apparatus, ultrasonic image treatment apparatus, medical image diagnostic apparatus, and ultrasonic image processing program |
KR101484958B1 (en) | 2012-03-28 | 2015-01-21 | 삼성메디슨 주식회사 | Ultrasound system and method for obtaining ultrasound image |
US9462994B2 (en) * | 2012-05-11 | 2016-10-11 | 3M Innovative Properties Company | Bioacoustic sensor with active noise correction |
US8777856B2 (en) | 2012-06-26 | 2014-07-15 | General Electric Company | Diagnostic system and method for obtaining an ultrasound image frame |
US9913967B2 (en) | 2012-07-06 | 2018-03-13 | Michael Zhadkevich | Occluding catheter and dynamic method for prevention of stroke |
US9301032B1 (en) * | 2012-07-26 | 2016-03-29 | Heartbuds, Llc | Stethoscope chestpiece usable with a portable electronic device and related methods |
US9366754B2 (en) | 2012-08-17 | 2016-06-14 | General Electric Company | Ultrasound imaging system and method |
JP6096459B2 (en) | 2012-10-04 | 2017-03-15 | 東芝メディカルシステムズ株式会社 | Ultrasonic diagnostic equipment |
US9492138B2 (en) | 2012-10-15 | 2016-11-15 | Rijuven Corp | Mobile front-end system for comprehensive cardiac diagnosis |
RU2539990C2 (en) | 2012-11-15 | 2015-01-27 | Федеральное бюджетное учреждение науки Центральный научно-исследовательский институт эпидемиологии Роспотребнадзора | Method of complex evaluation of indications for administration of cardiometabolic therapy in case of infectious diseases |
US9675322B2 (en) * | 2013-04-26 | 2017-06-13 | University Of South Carolina | Enhanced ultrasound device and methods of using same |
KR101435581B1 (en) | 2013-05-22 | 2014-08-28 | 이병훈 | Compound medical device |
JP5639321B1 (en) | 2013-06-26 | 2014-12-10 | オリンパスメディカルシステムズ株式会社 | Ultrasonic observation system and method of operating the ultrasonic observation system |
KR101643620B1 (en) | 2013-08-29 | 2016-07-29 | 삼성전자주식회사 | Ultrasound diagnostic apparatus and operating method thereof |
US9364155B2 (en) | 2013-09-25 | 2016-06-14 | Bardy Diagnostics, Inc. | Self-contained personal air flow sensing monitor |
US10186171B2 (en) | 2013-09-26 | 2019-01-22 | University Of South Carolina | Adding sounds to simulated ultrasound examinations |
US20150294085A1 (en) | 2014-04-14 | 2015-10-15 | Elwha LLC, a limited company of the State of Delaware | Devices, systems, and methods for automated enhanced care rooms |
US9504616B2 (en) | 2014-09-11 | 2016-11-29 | General Electric Company | Infant patient transfer device with heart rate sensor |
US9451896B2 (en) | 2014-09-23 | 2016-09-27 | Inovise Medical, Inc. | Hand-manipulable, ECG and acoustic, cardiography device |
WO2016078992A1 (en) | 2014-11-18 | 2016-05-26 | Koninklijke Philips N.V. | Apparatus for visualizing tissue property |
KR102373132B1 (en) | 2014-12-26 | 2022-03-11 | 삼성메디슨 주식회사 | An ultrasonic probe apparatus and an ultrasonic imaging apparatus using the same |
US20160296200A1 (en) | 2015-01-15 | 2016-10-13 | Jose Luis Hinojosa | MD (The Master Diagnostician) |
US20160287207A1 (en) * | 2015-04-02 | 2016-10-06 | Yan Xue | Smart medical examination and communication apparatus |
US9349098B1 (en) | 2015-05-14 | 2016-05-24 | James Albert Ionson | Cognitive medical and industrial inspection system and method |
US10058247B2 (en) | 2015-05-20 | 2018-08-28 | Comprehensive Telemedicine | Multipurpose diagnostic examination apparatus and system |
WO2016207092A1 (en) | 2015-06-26 | 2016-12-29 | Koninklijke Philips N.V. | System and method for generating an ultrasonic image |
KR101616473B1 (en) | 2015-07-16 | 2016-04-28 | 이병훈 | Smartphone with telemedical device |
US20170086778A1 (en) | 2015-09-29 | 2017-03-30 | International Business Machines Corporation | Capture and analysis of body sounds |
CA3041237A1 (en) | 2015-10-22 | 2017-04-27 | Tyto Care Ltd. | System, method and computer program product for physiological monitoring |
RU2637601C2 (en) | 2015-12-04 | 2017-12-05 | Юрий Иванович Аверьянов | Acoustical method for measurement of arterial pressure and other physical parameters of blood and cardiovascular system |
WO2017104998A1 (en) | 2015-12-15 | 2017-06-22 | Samsung Electronics Co., Ltd. | Ultrasound apparatus, controlling method thereof and telemedicine system |
US10561320B2 (en) | 2015-12-21 | 2020-02-18 | Zoll Medical Corporation | Time synchronization in a medical device system or network |
US10667787B2 (en) | 2016-03-01 | 2020-06-02 | EchoNous, Inc. | Ultrasound system with docking station and dockable ultrasound probe |
CA3016903A1 (en) | 2016-03-09 | 2017-09-14 | EchoNous, Inc. | Ultrasound image recognition systems and methods utilizing an artificial intelligence network |
US10499844B2 (en) | 2016-07-01 | 2019-12-10 | Bloom Technologies NV | Systems and methods for health monitoring |
EP4296720A3 (en) | 2016-08-17 | 2024-02-28 | California Institute of Technology | Enhanced stethoscope devices |
US10231691B2 (en) | 2016-09-09 | 2019-03-19 | Mustafa Behnan Sahin | Audible ultrasound physical examination device |
CN107126231B (en) * | 2017-06-20 | 2020-06-09 | 云南大学 | Internal deep layer major-middle artery local pulse wave velocity detection probe |
US10507009B2 (en) * | 2017-10-05 | 2019-12-17 | EchoNous, Inc. | System and method for fusing ultrasound with additional signals |
-
2019
- 2019-10-04 EP EP19871815.7A patent/EP3863521A4/en active Pending
- 2019-10-04 US US16/593,173 patent/US11647977B2/en active Active
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- 2019-10-04 JP JP2021543992A patent/JP2022508629A/en active Pending
- 2019-10-04 CA CA3115470A patent/CA3115470A1/en active Pending
- 2019-10-04 WO PCT/US2019/054677 patent/WO2020076627A1/en active Application Filing
- 2019-10-04 CN CN201980076255.7A patent/CN113056234A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050165310A1 (en) * | 2002-03-27 | 2005-07-28 | Herve Bindefeld | Apparatus for screening and diagnosing by dual stethoscopic and doppler detection |
WO2005037096A1 (en) * | 2003-09-23 | 2005-04-28 | Meditron Asa | Medical diagnostic apparatus and method for measuring blood pressure |
US9078571B2 (en) * | 2005-11-15 | 2015-07-14 | Active Signal Technologies, Inc. | High sensitivity noise immune stethoscope |
US20160045183A1 (en) * | 2013-04-05 | 2016-02-18 | Samsung Electronics Co., Ltd. | Electronic stethoscope apparatus, automatic diagnostic apparatus and method |
US20160100817A1 (en) * | 2014-10-14 | 2016-04-14 | Arsil Nayyar Hussain | Systems, devices, and methods for capturing and outputting data regarding a bodily characteristic |
Non-Patent Citations (1)
Title |
---|
See also references of EP3863521A4 * |
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CN113056234A (en) | 2021-06-29 |
US20200107800A1 (en) | 2020-04-09 |
EP3863521A1 (en) | 2021-08-18 |
CA3115470A1 (en) | 2020-04-16 |
US11647977B2 (en) | 2023-05-16 |
AU2019356470A1 (en) | 2021-05-13 |
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EP3863521A4 (en) | 2022-05-18 |
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