WO2020073018A3 - Test cartridges - Google Patents
Test cartridges Download PDFInfo
- Publication number
- WO2020073018A3 WO2020073018A3 PCT/US2019/054887 US2019054887W WO2020073018A3 WO 2020073018 A3 WO2020073018 A3 WO 2020073018A3 US 2019054887 W US2019054887 W US 2019054887W WO 2020073018 A3 WO2020073018 A3 WO 2020073018A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cartridges
- loaded
- imaging
- growth analysis
- differential growth
- Prior art date
Links
- 238000009635 antibiotic susceptibility testing Methods 0.000 abstract 2
- 230000034373 developmental growth involved in morphogenesis Effects 0.000 abstract 2
- 238000003384 imaging method Methods 0.000 abstract 2
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- -1 fluorescent tags Substances 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 239000006249 magnetic particle Substances 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
- C12Q1/20—Testing for antimicrobial activity of a material using multifield media
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/021—Adjust spacings in an array of wells, pipettes or holders, format transfer between arrays of different size or geometry
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/042—Caps; Plugs
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/043—Hinged closures
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/065—Valves, specific forms thereof with moving parts sliding valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
- G01N2035/0429—Sample carriers adapted for special purposes
- G01N2035/0436—Sample carriers adapted for special purposes with pre-packaged reagents, i.e. test-packs
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0439—Rotary sample carriers, i.e. carousels
- G01N2035/0446—Combinations of the above
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Fluid Mechanics (AREA)
- Robotics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17/282,623 US20230241603A1 (en) | 2018-10-04 | 2019-10-04 | Test cartridges |
CA3115289A CA3115289A1 (en) | 2018-10-04 | 2019-10-04 | Test cartridges |
AU2019354837A AU2019354837A1 (en) | 2018-10-04 | 2019-10-04 | Test cartridges |
CN201980080462.XA CN113272654A (en) | 2018-10-04 | 2019-10-04 | Test box |
JP2021518616A JP2022512605A (en) | 2018-10-04 | 2019-10-04 | Test cartridge |
EP19868804.6A EP3861357A4 (en) | 2018-10-04 | 2019-10-04 | Test cartridges |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862741253P | 2018-10-04 | 2018-10-04 | |
US62/741,253 | 2018-10-04 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2020073018A2 WO2020073018A2 (en) | 2020-04-09 |
WO2020073018A3 true WO2020073018A3 (en) | 2020-05-14 |
WO2020073018A9 WO2020073018A9 (en) | 2020-08-13 |
Family
ID=70054893
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2019/054887 WO2020073018A2 (en) | 2018-10-04 | 2019-10-04 | Test cartridges |
PCT/US2019/054885 WO2020073016A1 (en) | 2018-10-04 | 2019-10-04 | Microbial analysis without cell purification |
PCT/US2019/054888 WO2020073019A2 (en) | 2018-10-04 | 2019-10-04 | Detection and analysis of cells |
PCT/US2019/054884 WO2020073015A1 (en) | 2018-10-04 | 2019-10-04 | Analysis instrument |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2019/054885 WO2020073016A1 (en) | 2018-10-04 | 2019-10-04 | Microbial analysis without cell purification |
PCT/US2019/054888 WO2020073019A2 (en) | 2018-10-04 | 2019-10-04 | Detection and analysis of cells |
PCT/US2019/054884 WO2020073015A1 (en) | 2018-10-04 | 2019-10-04 | Analysis instrument |
Country Status (7)
Country | Link |
---|---|
US (4) | US20220033889A1 (en) |
EP (4) | EP3861357A4 (en) |
JP (4) | JP2022512597A (en) |
CN (4) | CN113287017A (en) |
AU (4) | AU2019354837A1 (en) |
CA (4) | CA3115262A1 (en) |
WO (4) | WO2020073018A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20200056220A1 (en) * | 2018-08-17 | 2020-02-20 | Genefluidics, Inc. | Generation of data for use with antimicrobials |
EP4045678A1 (en) * | 2019-10-29 | 2022-08-24 | Quantum-Si Incorporated | Systems and methods for sample preparation |
CN112881267A (en) * | 2019-11-29 | 2021-06-01 | 希森美康株式会社 | Cell analysis method, device, system, and program, and method, device, and program for generating artificial intelligence algorithm for training |
US20210162398A1 (en) * | 2019-12-03 | 2021-06-03 | RPI Consulting, LLC | Medical testing device |
EP4153972A1 (en) * | 2020-05-20 | 2023-03-29 | YSI, Inc. | Swept frequency fluorometer |
KR102551052B1 (en) * | 2020-12-28 | 2023-07-04 | 주식회사 어큐노스 | Apparatus and method for distinguishing antibiotics susceptibility |
WO2024059305A1 (en) * | 2022-09-15 | 2024-03-21 | General Electric Company | Method and apparatus for using lyophilized reagent beads for antimicrobial susceptibility testing |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060046246A1 (en) * | 2003-04-24 | 2006-03-02 | Qiandong Zeng | Genus, group, species and/or strain specific 16S rDNA sequences |
US20110028563A1 (en) * | 2007-10-23 | 2011-02-03 | Wild Child | Anti-microbial composition |
US20120045826A1 (en) * | 2008-09-24 | 2012-02-23 | Greg Yantz | Kits and devices for detecting analytes |
WO2012035302A1 (en) * | 2010-09-16 | 2012-03-22 | The University Court Of The University Of Edinburgh | Binding and non-binding polymers |
US20150152467A1 (en) * | 2013-12-04 | 2015-06-04 | Pocared Diagnostics Ltd. | Filter Arrangement with Slider Valve and Method for Using the Same |
US20180088141A1 (en) * | 2016-04-22 | 2018-03-29 | SeLux Diagnostics, Inc. | Performing antimicrobial susceptibility testing and related systems and methods |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7070925B1 (en) * | 1996-07-16 | 2006-07-04 | Gen-Probe Incorporated | Method for determining the presence of an RNA analyte in a sample using a modified oligonucleotide probe |
DE19916610A1 (en) * | 1998-05-22 | 1999-11-25 | Creatogen Biosciences Gmbh | Detecting antibiotic resistance in microorganisms by in situ characterization of probes |
US6251624B1 (en) * | 1999-03-12 | 2001-06-26 | Akzo Nobel N.V. | Apparatus and method for detecting, quantifying and characterizing microorganisms |
EP1432786B1 (en) * | 2001-09-06 | 2009-07-22 | Genomic Profiling Systems, Inc. | Rapid detection of replicating cells |
DE60327775D1 (en) * | 2002-06-24 | 2009-07-09 | Exiqon As | METHODS AND SYSTEMS FOR THE DETECTION AND ISOLATION OF NUCLEIC ACID SEQUENCES |
WO2005008219A2 (en) * | 2003-07-18 | 2005-01-27 | Bio-Rad Laboratories, Inc. | System and method for multi-analyte detection |
US20050152955A1 (en) * | 2003-12-16 | 2005-07-14 | Akhave Jay R. | Electrostatically self-assembled antimicrobial coating for medical applications |
US20180243741A1 (en) * | 2004-05-02 | 2018-08-30 | Fluidigm Corporation | Thermal reaction device and method for using the same |
EP1852512B1 (en) * | 2006-05-02 | 2011-11-02 | Universite Pierre Et Marie Curie | Microorganisms detection and enumeration method |
DE102008024567A1 (en) * | 2008-05-21 | 2009-12-03 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin | Method for measuring concentration of measuring substance in biological sample using molecular fluorescence resonance energy transfer-biosensors, involves irradiating sample with excitation light of spectral region |
US20100081131A1 (en) * | 2008-10-01 | 2010-04-01 | Ach Robert A | Identification of microbes using oligonucleotide based in situ hybridization |
US20110269130A1 (en) * | 2008-10-24 | 2011-11-03 | Song Shi | Antibiotice Susceptibility Profiling Methods |
US20120045748A1 (en) * | 2010-06-30 | 2012-02-23 | Willson Richard C | Particulate labels |
US9714943B2 (en) * | 2010-12-30 | 2017-07-25 | University Of South Florida | Methods and materials for capture antibody targeted fluorescent in-situ hybridization (CAT-FISH) |
AU2013225823A1 (en) * | 2012-02-29 | 2014-09-18 | President And Fellows Of Harvard College | Rapid antibiotic susceptibility testing |
US9052314B2 (en) * | 2013-03-14 | 2015-06-09 | Silver Lake Research Corporation | Biomarkers for detecting the presence of bacteria |
CA2900215A1 (en) * | 2013-03-15 | 2014-09-18 | Illumina, Inc. | System and method for generating or analyzing a biological sample |
EP2886660A1 (en) * | 2013-12-20 | 2015-06-24 | Rigas Tehniska universitate | A fluorescent in situ hybridization method for identification of a microorganism |
US10023895B2 (en) * | 2015-03-30 | 2018-07-17 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing |
EP3314007B1 (en) * | 2015-06-25 | 2024-01-24 | Native Microbials, Inc. | Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon |
EP3301454B1 (en) * | 2016-10-03 | 2019-08-28 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing |
JP7246316B2 (en) * | 2016-12-06 | 2023-03-27 | マイクロウブデックス、インコーポレイテッド | RNASE for improved microbial detection and antimicrobial susceptibility testing |
-
2019
- 2019-10-04 JP JP2021518514A patent/JP2022512597A/en active Pending
- 2019-10-04 JP JP2021518616A patent/JP2022512605A/en active Pending
- 2019-10-04 WO PCT/US2019/054887 patent/WO2020073018A2/en unknown
- 2019-10-04 CN CN201980080506.9A patent/CN113287017A/en active Pending
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- 2019-10-04 US US17/282,630 patent/US20220033889A1/en active Pending
- 2019-10-04 CN CN201980080462.XA patent/CN113272654A/en active Pending
- 2019-10-04 AU AU2019355198A patent/AU2019355198A1/en active Pending
- 2019-10-04 EP EP19870007.2A patent/EP3860629A4/en active Pending
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- 2019-10-04 JP JP2021518515A patent/JP2022512598A/en active Pending
- 2019-10-04 EP EP19868337.7A patent/EP3860452A4/en active Pending
- 2019-10-04 CA CA3115289A patent/CA3115289A1/en active Pending
- 2019-10-04 WO PCT/US2019/054885 patent/WO2020073016A1/en unknown
- 2019-10-04 WO PCT/US2019/054888 patent/WO2020073019A2/en unknown
- 2019-10-04 CA CA3115279A patent/CA3115279A1/en active Pending
- 2019-10-04 AU AU2019353145A patent/AU2019353145A1/en active Pending
- 2019-10-04 WO PCT/US2019/054884 patent/WO2020073015A1/en unknown
- 2019-10-04 US US17/282,633 patent/US20230235411A1/en active Pending
- 2019-10-04 CN CN201980080492.0A patent/CN113260712A/en active Pending
- 2019-10-04 AU AU2019356023A patent/AU2019356023A1/en active Pending
- 2019-10-04 EP EP19868682.6A patent/EP3861345A4/en active Pending
- 2019-10-04 CA CA3115287A patent/CA3115287A1/en active Pending
- 2019-10-04 US US17/282,623 patent/US20230241603A1/en active Pending
- 2019-10-04 CN CN201980080457.9A patent/CN113260371A/en active Pending
- 2019-10-04 US US17/282,627 patent/US20210349082A1/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060046246A1 (en) * | 2003-04-24 | 2006-03-02 | Qiandong Zeng | Genus, group, species and/or strain specific 16S rDNA sequences |
US20110028563A1 (en) * | 2007-10-23 | 2011-02-03 | Wild Child | Anti-microbial composition |
US20120045826A1 (en) * | 2008-09-24 | 2012-02-23 | Greg Yantz | Kits and devices for detecting analytes |
WO2012035302A1 (en) * | 2010-09-16 | 2012-03-22 | The University Court Of The University Of Edinburgh | Binding and non-binding polymers |
US20150152467A1 (en) * | 2013-12-04 | 2015-06-04 | Pocared Diagnostics Ltd. | Filter Arrangement with Slider Valve and Method for Using the Same |
US20180088141A1 (en) * | 2016-04-22 | 2018-03-29 | SeLux Diagnostics, Inc. | Performing antimicrobial susceptibility testing and related systems and methods |
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