WO2020055135A3 - Composition for treating wound or scar, comprising hydrogel patch - Google Patents

Composition for treating wound or scar, comprising hydrogel patch Download PDF

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Publication number
WO2020055135A3
WO2020055135A3 PCT/KR2019/011781 KR2019011781W WO2020055135A3 WO 2020055135 A3 WO2020055135 A3 WO 2020055135A3 KR 2019011781 W KR2019011781 W KR 2019011781W WO 2020055135 A3 WO2020055135 A3 WO 2020055135A3
Authority
WO
WIPO (PCT)
Prior art keywords
scar
composition
wound
hydrogel patch
induces
Prior art date
Application number
PCT/KR2019/011781
Other languages
French (fr)
Korean (ko)
Other versions
WO2020055135A2 (en
Inventor
김정범
Original Assignee
주식회사 슈파인세라퓨틱스
울산과학기술원
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 슈파인세라퓨틱스, 울산과학기술원 filed Critical 주식회사 슈파인세라퓨틱스
Publication of WO2020055135A2 publication Critical patent/WO2020055135A2/en
Publication of WO2020055135A3 publication Critical patent/WO2020055135A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention relates to a composition for treating a wound or scar, comprising a hydrogel patch. The composition or hydrogel according to one aspect induces fibroblasts and keratinocytes to move to and proliferate in a wounded area, thereby induces early closure of a wound, induces structural reconstruction of the skin layers, and thus can be usefully employed in the prevention, alleviation, or treatment of a skin wound or scar.
PCT/KR2019/011781 2018-09-11 2019-09-11 Composition for treating wound or scar, comprising hydrogel patch WO2020055135A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2018-0108521 2018-09-11
KR20180108521 2018-09-11

Publications (2)

Publication Number Publication Date
WO2020055135A2 WO2020055135A2 (en) 2020-03-19
WO2020055135A3 true WO2020055135A3 (en) 2020-05-07

Family

ID=69778040

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2019/011781 WO2020055135A2 (en) 2018-09-11 2019-09-11 Composition for treating wound or scar, comprising hydrogel patch

Country Status (2)

Country Link
KR (2) KR20200030022A (en)
WO (1) WO2020055135A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4190317A1 (en) 2020-09-01 2023-06-07 Cellartgen Inc. Extracellular matrix-supported biomimetic tissue adhesive hydrogel patch
CN112587515A (en) * 2020-12-18 2021-04-02 张青 Application of licorice flavonoids compounds in preparation of medicines for preventing and/or treating scars

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004535836A (en) * 2000-11-14 2004-12-02 エヌ．ブイ．アール． ラブズ インコーポレイテッド Crosslinked hyaluronic acid-laminin gels and their use in cell culture and medical implants
US20070010831A1 (en) * 2002-08-01 2007-01-11 Romero-Ortega Mario I Biomimetic biosynthetic nerve implant
KR20110002741A (en) * 2009-07-02 2011-01-10 아주대학교산학협력단 In situ forming hydrogel and biomedical use thereof
KR20150013433A (en) * 2012-01-31 2015-02-05 웨이크 포리스트 유니버시티 헬스 사이언시즈 Innervation of engineered structures

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004535836A (en) * 2000-11-14 2004-12-02 エヌ．ブイ．アール． ラブズ インコーポレイテッド Crosslinked hyaluronic acid-laminin gels and their use in cell culture and medical implants
US20070010831A1 (en) * 2002-08-01 2007-01-11 Romero-Ortega Mario I Biomimetic biosynthetic nerve implant
KR20110002741A (en) * 2009-07-02 2011-01-10 아주대학교산학협력단 In situ forming hydrogel and biomedical use thereof
KR20150013433A (en) * 2012-01-31 2015-02-05 웨이크 포리스트 유니버시티 헬스 사이언시즈 Innervation of engineered structures

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ARULMOLI, J. ET AL.: "Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering", ACTA BIOMATERIALIA, vol. 43, 2016, pages 122 - 138, XP055548151, DOI: 10.1016/j.actbio.2016.07.043 *

Also Published As

Publication number Publication date
KR20210075051A (en) 2021-06-22
WO2020055135A2 (en) 2020-03-19
KR20200030022A (en) 2020-03-19

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