WO2020052089A1

WO2020052089A1 - Interlock system for particle dose safety protection

Info

Publication number: WO2020052089A1
Application number: PCT/CN2018/117781
Authority: WO
Inventors: 曹海林; 冯汉升; 李实�; 王守元; 张静; 宋云涛; 丁开忠; 陈根; 陈永华
Original assignee: 合肥中科离子医学技术装备有限公司
Priority date: 2018-09-14
Filing date: 2018-11-28
Publication date: 2020-03-19
Also published as: CN109091767A

Abstract

An interlock system for particle dose safety protection, comprising a particle accelerator (1), an in-accelerator beam current cutting device (2), a therapeutic room front end beam current cutting device (3), a beam current dose detection device (4), several therapeutic rooms (5), a transmission system main line beam current cutting device (6), a first controller (7), and a second controller (8). The in-accelerator beam current cutting device (2) is disposed in the particle accelerator (1), and the transmission system main line beam current cutting device (6) is disposed on a beam current transmission main line. The system has the following beneficial effect: by means of detection by the beam current dose monitoring device (4) in the therapeutic room, once the dose delivered to the body of a patient is found to go beyond a safe range, interlock is triggered immediately, so as to control the beam current cutting devices (2, 3, 6) at the different positions in a particle therapy system to perform beam current cutting, in which case, the purpose of multi-point beam current cutting and redundant beam current cutting is achieved, safety and redundancy of the interlock system are ensured, and safety control is provided for particle radiotherapy.

Description

Interlocking system for particle dose safety protection

Technical field

The invention belongs to the field of particle medical safety interlocking, and relates to a particle dose safety protection interlocking technology, in particular to a particle dose safety protection interlocking system.

Background technique

In particle radiotherapy for cancer treatment, the accelerator accelerates the particles to a certain energy, and then sends the particle beam to the treatment room to irradiate the patient. In the event of an emergency, in order to prevent the particle beam irradiated into the patient from exceeding the safe dose, the beam current needs to be cut off immediately. Because the particle treatment system is very large, the distance from the accelerator to multiple treatment rooms is long, resulting in a slow beam cutoff efficiency. In addition, the particle therapy system is safe for the treatment of patients, and the amount of radiation generated when the beam is cut off is easy to cause damage to the patient's body. To solve the above defects, a solution is now provided.

Summary of the Invention

The purpose of the present invention is to solve the problem of the conventional particle radiotherapy for cancer treatment. After the accelerator accelerates the particles to a certain energy, the particle beam is delivered to the treatment room to irradiate the patient. In the event of an emergency, in order to avoid irradiation, The patient's particle beam exceeds the safe dose and needs to be cut off immediately. Because the particle treatment system is very large, the distance from the accelerator to multiple treatment rooms is relatively long, resulting in a slow beam cutoff efficiency, and the particle treatment system is safe for patient treatment. It is easy to damage the patient's body due to the large amount of radiation generated when the beam is cut off, and provides an interlocking system for particle dose safety protection.

The object of the present invention can be achieved by the following technical solutions;

An interlocking system for particle dose safety protection includes a particle accelerator, an intra-accelerator beam cut-off device, a front-end beam cut-off device of a treatment room, a beam dose detection device, several treatment rooms, and a main line beam cut-off device of a transport system A first controller and a second controller, wherein the particle accelerator is provided with a beam cut-off device, and the transport system main line beam cut-off device is provided on the beam transport main line, and a plurality of treatments are entered in the beam The front end of the room is provided with a beam cutting device at the front of the treatment room. A plurality of beam treatment units are provided inside the treatment room. The beam dose monitoring device is used to monitor in real time whether the dose entering the patient is within a safe range. .

Further, the beam cutting device in the accelerator is located in a particle accelerator to avoid generating a beam. This method has the highest safety and the smallest radiation effect, and the beam cutting device in the accelerator is used to accelerate particles. In order to prevent the high-energy particle beam from entering the acceleration area, the particle transport system is used to deliver a high-speed particle stream to the treatment room.

Further, the transport system trunk line beam cutting device is located on the particle transport system trunk line, and the transport system trunk line beam cutting device is used to cut off the particle beam flow before high-speed particles enter all treatment rooms. It is found that the dose delivered to the patient's body exceeds the safe range, and the interlock will be triggered immediately to control the beam cutting device at different positions in the particle therapy system to perform beam cutting. In this way, multi-point beam cutting and redundant beam cutting are achieved. The purpose is to ensure the safety and redundancy of the interlocking system. The mainline beam cutoff device of the transport system is located on the mainline of the particle transport system, and the mainline beam cutoff device of the transport system is used when high-speed particles enter. The particle beam is cut off in front of all treatment rooms, and the transport system trunk line beam cutoff device is located on the particle transport system trunk line, and the transport system trunk line beam cutoff device is used to cut off particles before high-speed particles enter all treatment rooms. Beam, the beam cut-off device in the accelerator is a radio frequency system of the accelerator, the front-end beam cut-off device of the treatment room and The mainline beam cutting device of the transport system is a particle flow blocker. The front-end beam cutting device of the treatment room and the main system beam cutting device of the transport system include a solenoid valve, a cylinder, and a block. The movable end of the cylinder's piston rod and The blocking block is fixedly connected, and the solenoid valve is connected to the cylinder. By controlling the compressed air entering the cylinder, the cylinder piston rod moves up and down, and the blocking block moves up and down accordingly, so that the blocking block can be quickly inserted into the particle transport path, and the blocking beam has been reached. The beam dose monitoring device for streaming purposes is an ionization chamber.

Further, the front-end beam cutting device of the treatment room is located at the front of the particle transport system entering a single treatment room, and the front-end beam cutting device of the treatment room is used to prevent high-speed particle beams from entering the corresponding treatment room.

Further, the beam dose monitoring device is located in several treatment rooms, and the beam dose monitoring device is used to constantly monitor the particle beam passing through the beam dose monitoring device. Once it is found that the dose passing through the beam dose into the patient's body exceeds the safety Range, interlock will be triggered immediately for safety protection.

Further, the beam dose monitoring device in any one of the treatment rooms detects that the dose entering the patient's body exceeds a safe range, and will immediately send an interlock request to the first controller, and the first controller will simultaneously send to the accelerator The internal beam cut-off device and the trunk line beam cut-off device of the transport system send interlock commands to control the two to cut off the beam together.

Further, the beam current dose monitoring device in any one of the plurality of treatment rooms detects that the dose entering the patient's body exceeds a safe range, and sends an interlock request to the first controller while sending an interlock to the second controller. The lock request, the second controller will send an interlock command to the front-end beam cutting device of the treatment room, and control the front-end beam cutting device of the treatment room to cut off the beam.

Further, the beam cut-off device at the front end of the treatment room will perform beam cut-off according to the current usage of the treatment room. Only the treatment room that is performing the treatment, the beam cut-off device at the front end of the treatment room performs interlock to cut off the beam and does not perform treatment The front-end beam cut-off device of the treatment room will not execute the interlock command.

Further, the first controller and the second controller are two independent logical controllers, and the first controller and the second controller are used as interlocking redundancy with each other, and the response time should be in the microsecond level.

Further, the interlocking method of the system specifically includes the following steps:

S1. When the particle therapy system is in a treatment state, the beam dose monitoring device inside each treatment room performs real-time monitoring;

S2. When it is detected that the dose delivered to the patient's body exceeds a safe range, the beam dose monitoring device sends a safety interlock request;

S3, the two independent controllers, the first controller and the second controller, will receive the interlocking request at the same time, and send an interlocking command to the beam cutting device responsible respectively;

S4. The beam current cut-off device in the accelerator and the trunk line beam cut-off device of the transport system simultaneously receive the first controller interlock command to execute the beam cut-off action;

S5. The beam cut-off device at the front end of the treatment room will decide whether to execute the interlocking action according to the treatment conditions of different treatment rooms.

The beneficial effects of the present invention:

The invention provides a dose safety interlock system for a particle therapy system. The system detects the beam dose monitoring device in the treatment room. Once the dose delivered to the patient's body exceeds a safe range, the interlock will be triggered immediately to control the particles. The beam cutting devices at different positions in the treatment system perform beam cutting, thereby achieving the purpose of multi-point beam cutting and redundant beam cutting, ensuring the safety and redundancy of the interlocking system, and providing safety for particle radiotherapy. Protection.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to facilitate understanding by those skilled in the art, the present invention is further described below with reference to the accompanying drawings.

FIG. 1 is a schematic diagram of a beam cutting layout of the particle therapy system of the present invention.

Fig. 2 is an interlocking flow chart for controlling particle beam cutoff according to the present invention.

FIG. 3 is a schematic diagram of a control structure of the present invention.

In the picture: 1. Particle accelerator; 2. Beam-cutting device in the accelerator; 3. Beam-cutting device at the front of the treatment room; 4. Beam dose monitoring device; 5. Treatment room; 6. Beam-cutting device for the main line of the transport system ; 7, the first controller; 8, the second controller.

The preferred embodiment of the present invention

The technical solution of the present invention will be described clearly and completely in combination with the following embodiments. Obviously, the described embodiments are only a part of the embodiments of the present invention, but not all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

As shown in Figure 1-3, an interlock system for particle dose safety protection includes a particle accelerator 1, an intra-accelerator beam cut-off device 2, a front-end beam cut-off device 3 in a treatment room, a beam dose detection device 4, and several A treatment room 5, a main line beam cutting device 6, a first controller 7 and a second controller 8, a particle accelerator 1 is provided with a beam cutting device 2, and a main transportation line is provided with a transportation system. The mainline beam cut-off device 6 is provided with a front-end beam cut-off device 3 for the treatment room at the front end of the beam entering several treatment rooms, and a plurality of treatment rooms 5 are provided with a beam dose monitoring device 4 and a beam dose monitoring device 4 for Real-time monitoring of whether the dose entering the patient is within a safe range.

The intra-accelerator beam cut-off device 2 is located in the particle accelerator 1, and the intra-accelerator beam cut-off device 2 is used to prevent the beam from entering the acceleration region before the particles are accelerated into high-energy particle beams to avoid generating a beam, which is safe. It has the highest performance and the smallest radiation effect, and the particle transport system is used to deliver a high-speed particle stream to the treatment room 5.

The transport system trunk line beam cut-off device 6 is located on the particle transport system trunk line, and the transport system trunk line beam cut-off device 6 is used to cut off the particle beam flow before high-speed particles enter all treatment rooms. Once found to be delivered to the patient's body If the dose exceeds the safety range, the interlock will be immediately triggered to control the beam cutting device at different positions in the particle therapy system to perform beam cutting. In this way, the purpose of multi-point beam cutting and redundant beam cutting can be ensured. The safety and redundancy of the locking system. The beam cut-off device 2 in the accelerator is an RF system of the accelerator. The front-end beam cut-off device 3 in the treatment room and the trunk line beam cut-off device 6 of the transport system are a kind of particle flow blocker. The front-end beam cut-off device 3 of the treatment room and the transport system main-line beam cut-off device 6 each include a solenoid valve, a cylinder, and a block. The movable end of the cylinder's piston rod is fixedly connected to the block, and the solenoid valve is connected to the cylinder. Compressed air enters the cylinder to realize the up and down movement of the piston rod of the cylinder, and the blocking block moves up and down accordingly, so that the blocking block can be quickly inserted into the particle transport path. The beam dose monitoring device 4 which has achieved the purpose of blocking the beam is an ionization chamber.

The beam cutting device 3 at the front of the treatment room is located at the front of the particle transport system entering the single treatment room 5, and the beam cutting device 3 at the front of the treatment room is used to prevent the high-speed particle beam from entering the corresponding treatment room.

The beam dose monitoring device 4 is located in several treatment rooms 5, and the beam dose monitoring device 4 is used to constantly monitor the particle beam passing through the beam dose monitoring device 4. Once it is found that the dose passing through the beam into the patient exceeds a safe range, Interlock will be triggered immediately for safety protection.

The beam dose monitoring device 4 in any of a number of treatment rooms 5 detects that the dose entering the patient's body is outside the safe range. The beam dose monitoring device 4 should be capable of monitoring whether the absolute dose entering the patient's body exceeds the safe range. An interlock request will be sent to the first controller 7 immediately, and the first controller 7 will send an interlock command to the beam cut-off device 2 in the accelerator and the trunk line cut-off device 6 of the transport system at the same time to control the two to cut off the beam together. .

The beam dose monitoring device 4 in any one of several treatment rooms 5 detects that the dose entering the patient's body exceeds a safe range, and sends an interlock request to the first controller 7 and an interlock to the second controller 8 The request, the second controller 8 will send an interlocking command to the front-end beam cutting device 3 of the treatment room to control the front-end beam cutting device 3 to cut off the beam.

The beam cut-off device 3 at the front of the treatment room will cut off the beam according to the current use of the treatment room. Only the treatment room that is performing the treatment. The beam cut-off device 3 at the front of the treatment room performs the interlock to cut off the beam. The front beam cut-off device 3 will not execute the interlock command.

The first controller 7 and the second controller 8 are two independent logical controllers, and the first controller 7 and the second controller 8 serve as interlocking redundancy with each other. The response time should be in the microsecond level to ensure that The dose into the patient's body meets safety requirements.

As shown in FIG. 3, the interlocking method of the system specifically includes the following steps:

S1. When the particle treatment system is in a treatment state, the beam flux monitoring device 4 in each treatment room 5 performs real-time monitoring;

S2. When it is detected that the dose delivered into the patient's body exceeds a safe range, the beam dose monitoring device 4 issues a safety interlock request;

S3, the two independent controllers, the first controller 7 and the second controller 8, will receive the interlocking request at the same time, and send an interlocking command to the beam cutting device responsible for each of them.

S4. The beam current cut-off device 2 in the accelerator and the trunk line beam cut-off device 6 of the transport system simultaneously receive the interlocking command of the first controller 7 to execute the beam cut-off action;

S5. The beam cut-off device 3 at the front end of the treatment room will decide whether to perform an interlocking action according to the treatment conditions performed in different treatment rooms.

The beneficial effects of the present invention:

When the dose safety interlock system for a particle therapy system is working, when the particle therapy system is in a treatment state, the internal beam dose monitoring device 4 in each treatment room 5 performs real-time monitoring, and when it is detected that the dose delivered to the patient's body exceeds When the safety range is reached, the beam dose monitoring device 4 issues a safety interlock request. The two independent controllers, the first controller 9 and the second controller 8, will receive the interlock request at the same time, and will be responsible for their respective beams. The cut-off device sends an interlock command. The beam cut-off device 2 in the accelerator and the trunk line cut-off device 6 of the transport system simultaneously receive the first controller 7 interlock command to execute the cut-off beam operation. The front-end beam cut-off device 3 in the treatment room will According to the different treatment rooms performing the treatment, decide whether to perform the interlocking action. The beam cutting device used for the dose safety interlocking of the particle therapy system can be a blocking device that prevents the beam from passing, according to the principle of different particle therapy systems. It can be a magnet device that causes the beam to deviate from the original path, or a power supply device that restricts particles from entering the acceleration field. The present invention aims to Ming particle beam therapy system of interlocking cut strategy and function, the specific form of the beam cutting device, without notice.

The preferred embodiments of the present invention disclosed above are only used to help explain the present invention. The preferred embodiment does not describe all the details in detail, nor does it limit the invention to the specific embodiments described. Obviously, many modifications and changes can be made according to the contents of this specification. These embodiments are selected and described in this specification in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can better understand and use the present invention. The invention is limited only by the claims and the full scope and equivalents thereof.

Industrial applicability

The specific working principle of the present invention is that the system detects the beam current dose monitoring device in the treatment room. Once it is found that the dose delivered to the patient's body exceeds a safe range, it will immediately trigger an interlock to control the beam current at different positions in the particle therapy system. The cutting device performs beam cutting, thereby achieving the purposes of multi-point beam cutting and redundant beam cutting, ensuring the safety and redundancy of the interlocking system, and providing safety guarantee for particle radiotherapy.

Claims

An interlocking system for particle dose safety protection is characterized in that it includes a particle accelerator (1), an intra-accelerator beam cutting device (2), a front-end beam cutting device (3) in a treatment room, and a beam dose detection device ( 4), several treatment rooms (5), a main line beam cutting device (6) of the transport system, a first controller (7) and a second controller (8), and a beam is arranged in the particle accelerator (1). Stream cutting device (2), and the transport system trunk line beam cutting device (6) is provided on the beam transport main line, and front ends of several treatment rooms are provided with beam cutting devices (3) A plurality of treatment rooms (5) are each provided with a beam dose monitoring device (4), and the beam dose monitoring device (4) is used to monitor in real time whether a dose entered into a patient is within a safe range.
The interlocking system for particle dose safety protection according to claim 1, characterized in that the intra-accelerator beam cut-off device (2) is located in the particle accelerator (1), and the intra-accelerator beam cut-off The device (2) is used to prevent the beam from entering the acceleration area before the particles are accelerated into a high-energy particle beam, and the particle transport system is used to transport a high-speed particle stream to the treatment room (5).
The interlocking system for particle dose safety protection according to claim 1, characterized in that the trunk line beam cut-off device (6) of the transport system is located on the trunk line of the particle transport system, and the transport The system main line beam cut-off device (6) is used to cut off the particle beam before high-speed particles enter all treatment rooms. The intra-accelerator beam cut-off device (2) is an accelerator's radio frequency system, and the front end of the treatment room is cut off by beams. The device (3) and the main line beam cut-off device (6) of the transport system are a kind of particle flow blocker. The front-end beam cut-off device (3) of the treatment room and the main line beam cut-off device (6) of the transport system both include electromagnetic The valve, the cylinder and the blocking block, the movable end of the piston rod of the cylinder is fixedly connected to the blocking block, the solenoid valve is connected to the cylinder, and the beam dose monitoring device (4) is an ionization chamber.
The interlocking system for particle dose safety protection according to claim 1, characterized in that the front-end beam cutting device (3) of the treatment room is located at the front end of the particle transport system entering a single treatment room (5), and The front-end beam cutting device (3) of the treatment room is used to prevent the high-speed particle beam from entering the corresponding treatment room.
The interlocking system for particle dose safety protection according to claim 1, wherein the beam dose monitoring device (4) is located in a plurality of treatment rooms (5), and the beam dose monitoring The device (4) is used to constantly monitor the particle beam passing through the beam dose monitoring device (4). Once it is found that the dose passing into the patient's body exceeds a safe range, an interlock will be triggered immediately for safety protection.
The interlocking system for particle dose safety protection according to claim 1, characterized in that the beam current dose monitoring device (4) in any one of the plurality of treatment rooms (5) detects entry into the patient's body If the dose exceeds the safe range, an interlock request will be immediately sent to the first controller (7), and the first controller (7) will simultaneously send the beam cut-off device (2) in the accelerator and the trunk line beam cut-off device of the transport system ( 6) Send an interlock command to control both to cut off the beam.
The interlocking system for particle dose safety protection according to claim 6, characterized in that the beam dose monitoring device (4) in any one of a plurality of the treatment rooms (5) detects entering the patient's body The dose exceeds the safe range. While sending the interlock request to the first controller (7), the interlock request is sent to the second controller (8), and the second controller (8) will cut off the beam to the front of the treatment room. The device (3) sends an interlock command to control the beam cutting device (3) at the front end of the treatment room to cut off the beam.
The interlocking system for particle dose safety protection according to claim 7, characterized in that the front-end beam cut-off device (3) of the treatment room will perform beam cut-off according to the current use situation of the treatment room. The treatment room (5) performing the treatment, the front-end beam cutting device (3) of the treatment room performs interlocking to cut off the beam, and the front-end beam cutting device (3) of the treatment room not performing the treatment will not execute the interlocking command.
The interlocking system for particle dose safety protection according to claim 1, wherein the first controller (7) and the second controller (8) are two independent logic controllers, and The first controller (7) and the second controller (8) act as interlocking redundancy with each other, and the response time should be in the microsecond level.
The interlocking system for particle dose safety protection according to claim 1, wherein the interlocking method of the system specifically comprises the following steps:

S1. When the particle treatment system is in a treatment state, the internal beam dose monitoring device (4) in each treatment room (5) performs real-time monitoring;

S2. When it is detected that the dose delivered to the patient's body exceeds a safe range, the beam dose monitoring device (4) issues a safety interlock request;

S3. The two independent controllers, the first controller (7) and the second controller (8), will receive the interlocking request at the same time, and send an interlocking command to the beam cutting device responsible for each of them.

S4. The beam current cut-off device (2) in the accelerator and the trunk line beam cut-off device (6) of the transport system simultaneously receive the interlock command from the first controller (7) to execute the beam cut-off action;

S5. The beam cut-off device (3) at the front end of the treatment room will decide whether to perform the interlocking action according to the treatment conditions performed by different treatment rooms.