WO2020023045A1 - Dispositif et procédés sans suture de fermeture d'une ouverture de tissu - Google Patents

Dispositif et procédés sans suture de fermeture d'une ouverture de tissu Download PDF

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Publication number
WO2020023045A1
WO2020023045A1 PCT/US2018/043974 US2018043974W WO2020023045A1 WO 2020023045 A1 WO2020023045 A1 WO 2020023045A1 US 2018043974 W US2018043974 W US 2018043974W WO 2020023045 A1 WO2020023045 A1 WO 2020023045A1
Authority
WO
WIPO (PCT)
Prior art keywords
base
receiving
tie strip
tissue
key
Prior art date
Application number
PCT/US2018/043974
Other languages
English (en)
Inventor
Brett D. CHRISTIANSEN
Christopher B. CHRISTIANSEN
James B. CHRISTIANSEN
Clancy B. CHRISTIANSEN
Candice S. CHRISTIANSEN
Bryce B. CHRISTIANSEN
Susan G. CHRISTIANSEN
Phillip Dietz
Original Assignee
Christiansen Brett D
Christiansen Christopher B
Christiansen James B
Christiansen Clancy B
Christiansen Candice S
Christiansen Bryce B
Christiansen Susan G
Phillip Dietz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christiansen Brett D, Christiansen Christopher B, Christiansen James B, Christiansen Clancy B, Christiansen Candice S, Christiansen Bryce B, Christiansen Susan G, Phillip Dietz filed Critical Christiansen Brett D
Priority to PCT/US2018/043974 priority Critical patent/WO2020023045A1/fr
Publication of WO2020023045A1 publication Critical patent/WO2020023045A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/08Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/085Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound with adhesive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00367Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
    • A61B2017/00407Ratchet means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/08Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B2017/081Tissue approximator

Definitions

  • a sutureless device and method for closing a tissue opening that minimizes the labor, skill, and cost typically required to properly close tissue lacerations.
  • Tissue wounds may be accidental or, a surgical incision and intentional.
  • animals also suffer from tissue wounds that require the skill of a veterinarian to close.
  • tissue wound closure The basic concept of tissue wound closure is to bring the two wound edges mechanically together in close alignment, both vertically and horizontally. When the wound edges are properly aligned, the wound heals more quickly, scarring is lessened and infections are decreased.
  • tissue wound closure is basic, the skills to properly close a tissue wound, using the current most common method of closure with sutures or tissue adhesive is done by a health care profession. It may take years to develop this skill. Access to health care providers is limited and often delayed requiring loss of time to get the repair done. In addition, the cost to get a wound repaired in the Emergency Department ranges anywhere from $500 up to $2,000.
  • the time period between the initial injury and the closure of the wound is also important. To lower the risk of infections it is essential that the wound be closed quickly. The longer the wound is left open, the more bacteria there is that enters the wound and begins to grow.
  • Several studies have shown that a tissue wound is best closed within six hours or less. Many doctors refer to this six-hour period as the“golden period.” Ideally a tissue wound should be closed within three hours. However, many times the patient is not near a medical facility or a doctor is not available for hours or even days. In addition, waiting times in Emergency Departments alone can be over 6 hours.
  • Previous wound closing methods included invasive and traumatizing methods such as sutures and staples. These methods required passing materials through the intact skin around the wound edges. These methods cause additional pain to the patient and increase the risk of infection. These methods, even if used by a skilled physician, may still cause pain and scarring caused by the sutures and staples themselves. It also requires expensive equipment and supplies that the general population do not have direct access to. To limit the pain, many doctors administer a local anesthetic. However, there are a number of adverse events that can occur from using these local anesthetics. These reasons are why such materials cannot be used by the general public and require a license and training.
  • Cyanoacrylates that can be purchased at the store are not suitable or approved for wound closures. They do not have an elasticity component built into the glue and are brittle causing the glue to separate before it is appropriately healed and the wound opens up, causing increased scaring.
  • sutureless devices included strips of fabric or surgical tape.
  • the wound is manually closed and the surgical tape is placed perpendicular to the tissue wound, preventing the wound from reopening.
  • surgical tape can only be applied to small, clean, shallow tissue wounds. These are not adjustable short of removing the entire bandage and replacing it. Removing the bandages may causes the wound to reopen again.
  • sutureless device that can be used easily by untrained users or by the individual themselves. That will allow the user to properly align the skin, and that can flex with the movement of the body.
  • the sutureless device should allow the user to use the device on jagged tissue wounds or contoured or rounded body parts.
  • the design and materials of this device will allow it to be manufactured in high volumes that allows it to be affordable and available to the general public. It will also not require the user to have special equipment, local anesthetic, or training in order to effectively use the product.
  • a principal object of the invention is to provide a sutureless device for easily closing an open tissue wound.
  • the invention easily closes an open tissue laceration, and to produce a device in such a way that it is easily accessible to all, including healthcare providers, veterinarians, and especially the general public.
  • the invention decreases the pain, infection and scarring associated with wound repair.
  • the invention significantly decreases the cost and inconvenience required to repair wounds that are found to be appropriate for closure by the device.
  • the object of the invention is to provide a device that allows the user to delicately close the tissue wound by properly aligning the two skin edges of the tissue wound both horizontally and vertically.
  • the device has flexible and expandable connections between each individual device to allow for irregular wounds or complex skin contour as well as the ability to flex with the movement of the body and adjust to the contour of the body.
  • Still another object of the invention is to provide a device that can be easily adjusted or readjusted for uneven or jagged tissue wounds.
  • the device will enable the individual to fine-tune the exact alignment of the wound for the best possible result in wound closure and decrease in scarring.
  • Another object the device is to allow it to be used as a single unit for a small laceration or as a group of attached units to close a larger or irregularly shaped laceration.
  • the present invention comprises two anchors that attach to opposing sides of an open tissue laceration.
  • the two anchors are connected together by means of a tie strip. As the two edges of the tissue wound are drawn together, the two anchors are brought together.
  • the tie strip ratcheting system prevents the anchors from separating and thus prevents the tissue wound from reopening.
  • a rack and pinion system is utilized.
  • the rack is located on the tie strip, and the pinion is located on a key.
  • a raised boss is located on one of the anchors that corresponds to an orifice on the bottom of the key.
  • the device may utilize a lever to control the distance between the two anchors.
  • the rack and pinion system converts the rotational motion of the key to the linear motion of the tie strip.
  • the movement of the tie strip causes the two anchors to come together and therefore closes the open wound.
  • the tie strip ratchet system prevents the anchor and the wound from reopening.
  • There is a release latch that can be lifted allowing the ratchet to be temporarily released such that you can adjust for potential over tightening, enabling you get the best possible wound closure.
  • a lever may be used to control the movement.
  • an optional lock may be utilized to prevent the movement of the tie strip.
  • Fig. 1 shows an elevated side plan view of the tissue closing device of the invention
  • Fig. 2 shows an array of the tissue closing device, illustrating how each tissue closing device is connected to the other tissue closing devices; in addition shows a key releasably connected to one of the tissue closing devices in the array;
  • Fig. 3 shows a side view of the tissue closing device that shows the device attached to a user’s skin and a tie strip bridging over an open tissue wound;
  • Fig. 4 shows a side view of the tissue closing device that shows the device attached to a user’s skin and a tie strip bridging over the tissue wound with the tissue wound closed and the wound’s edges properly aligned; in addition, shows a badged covering the device and the tissue wound;
  • Fig. 5 shows a bottom view of an array of the tissue closing device; showing the locations of the adhesive pads and an adhesive cover;
  • Fig. 6 shows a top view of an array of tissue closing devices, illustrating how the location of each tissue closing device may vary based upon the type and location of the tissue wound;
  • Fig. 7 shows a side view of the tissue closing device with an open wound showing how the tissue closing device bridges over an open wound, also illustrating how a key is position onto receiving base;
  • Fig. 8. shows a cross section view of the tissue closing device, showing how the teeth located on a tie strap interacts with a latch and a pawl;
  • Fig. 9. shows a top view of the device with the key placed on the receiving anchor
  • Fig. 10 shows an elevated side view of an array of tissue closing devices and the key; illustrating variable number of tissue closing devices that may be combined in the array;
  • Fig. 11 shows an elevated side view of an array of the receiving anchors, illustrating the connection between each device is flexible and the array may be adjustable for jagged wounds or adjust to the contour of the body;
  • Fig. 12 shows the a bottom view of the key
  • Fig. 13 shows an array of the tissue closing devices, illustrating how a user may utilize a cutting device such as scissors to separate the tissue closing devices;
  • Fig. 14 shows an elevated side view of an array of the devices, illustrating the connection between each device is flexible and the array may be adjustable for arced tissue wounds or adjust to the contour of the body;
  • Fig. 15 illustrates an elevated side view of the device that includes a lock that prevents movement of the tie strip
  • Fig. 16 shows a top view of the device with the lock that prevents movement of the tie strip
  • Fig. 17 shows a side view of the device with the lock in a closed position, therefore would prevent movement of the tie strip
  • Fig. 18 shows a side view of the device with the lock in an open position, therefore allowing movement of the tie strip
  • Fig. 19 shows a side view of the device with a lever; the lever being integrally formed with the receiving base;
  • Fig. 20 shows an elevated side view of the device with a lever that is integrally formed with receiving base
  • Fig. 21 shows an elevated side view of the device with a removable lever
  • Fig. 22 shows an elevated side view of the device that is formed in a shape arc to match the contours of the body, such as a finger.
  • Tissue closing device 32 Cross member Anchor base 34 Side
  • a tissue closing device 2 comprising of an anchor base 4, a receiving base 6, and a tie strap 8 for closing a tissue wound 100.
  • a key 50 comprising of a handle 52 and pinion 54.
  • Fig. 17, 18, 19 and 20 comprising the use of a lever 70.
  • the anchor base 4 and the receiving base 6 attach to a patient’s skin 102.
  • the anchor base 4 is attached near the edge of a tissue wound 100.
  • the receiving base 6 is attached on the opposite side near the edge of the tissue wound 100.
  • the anchor base 4 and the receiving base 6 is preferably composed of a semi-rigid material such as nylon or plastic; however, flexible materials, metals or any semi-rigid materials are suitable for use in the present invention.
  • the width and length of the anchor base 4 and the receiving base 6 vary based upon the size of the tissue wound 100. Larger tissue wounds 100 will require a larger sized anchor base 4 and receiving base 6.
  • tissue closing device 2 may be curve or arc to confirm with the shape of the body, such as a finger or chin.
  • the specific shape of the anchor base 4 and the receiving base 6 may also vary.
  • the adhesive 28 is for attaching the anchor base 4 and the receiving base 6 to the patient’s skin 102.
  • the adhesive 28 is generally any hydrophilic adhesive or medical adhesive agent such as a hydrocolloid, a hydrogel, or an acrylic polymer.
  • many different types of adhesives 28 may work and are well known in the profession. As one skilled in the art will recognize, if the size of the anchor base 4 and the receiving base 6 increases, the surface area of the adhesive 28 increases, thus increasing the strength of the connection between the skin 102 and the anchor base 4 or receiving base 6.
  • a pad 26 may be placed between the adhesive 28 and the bottom of the anchor base 4 or the receiving base 6.
  • the pad 26 may be installed in a recess 25 located on the base of the anchor base 4 and the receiving base 6.
  • the shape and depth of the recess 25 is similar to the pad 26.
  • the pad 26 will typically be flexible and more elastic than the anchor base 4 and the receiving base 6. The flexibility of the pad 26 will help maintain adhesion, minimize blister, and reduce irritation as well as adapts to irregularities of the surface of the skin 102.
  • an adhesive cover 27 protects the adhesive 28.
  • the adhesive cover 27 helps keep the adhesive 28 free of bacteria or viruses.
  • the adhesive cover 27 is a protective layer that may be peeled away immediately prior to use.
  • the adhesive cover 27 is coated paper but may be made of plastic or any other suitable material.
  • the adhesive cover 27 must be easily removable by the user. In application, many users will use protective gloves to assist them in obtaining a stronger grip on the adhesive cover 27.
  • a tab 29 is located on the edge of the adhesive cover 27. The tab 29 is generally made of the same material as the adhesive cover 27.
  • the tie strap 8 connects the receiving base 6 and the anchor base 4 by bridging over the tissue wound 100.
  • the tie strap 8 comprises a starting end 20, a tip 24, a rack 18, and a plurality of teeth 16.
  • the tie strap 8 is comprised of the same material as the anchor base 4 and the receiving base 6.
  • the starting end 20 is attached to the anchor base 4.
  • additional anchor buttresses 22 may be added.
  • the tie strap 8, anchor buttress 22, and the anchor base 4 are integrally formed from the same material. Located at the opposite end of the longitudinal axis of the tie strip 8 is the tip 24.
  • the tip 24 has a spearhead shape to allow the user to easily insert the tie strap 8 into a receiving body 10.
  • the tie strap 8 length, width and thickness vary based upon the size of the tissue wound 100 and the actual need. However, the size of the tie strap 8 must be able to withstand a tension force to prevent the tissue wound 100 from reopening.
  • the teeth 16 are axially spaced along the longitudinal axis of the tie strap 8 for engaging with a pawl 15, which is described below.
  • Located on the side of the tie strap 8 is the rack 18.
  • the rack 18 is essentially an axially spaced gear bar that engages with the pinion 54 or lever 70 as illustrated in Fig. 15 or any other mechanical device which will incrementally close the distance between receiving base 6 and anchor base 4. located on the key 50.
  • the location of the rack 18 and the teeth 16 may be located on any side of the tie strap 8.
  • Fig. 8 is an illustration of the receiving body 10 that is located on the receiving base 6.
  • the receiving body 10 includes a slide port 30, a cross member 32, two slides 34, and a latch 14.
  • the slide port 30 is an opening for reception of the tie strap 8.
  • the size of the slide port 30 is slightly larger than the size of the tie strap 8, such that the tie strap 8 will easily glide into the slide port 30 but small enough to prevent the tie strap 8 from freely moving.
  • the receiving body 10 is integrally formed on the receiving base 6.
  • a latch 14 is pivotally connected to the receiving body 10. However, the connection only allows the latch 14 to move when a force is applied to it.
  • the latch 14 includes the pawl 15 that extends from the latch 14 into the slide port 30. As the tie strap 8 is passed through the slide port 30, the slope of the teeth 16 push the pawl 15 away from the tie strap 8, allowing the tie strap 8 to slide further into the receiving body 10. When tension is applied to the tie strap 8 to withdraw it from the receiving body 10, the latch 14 acts to position the pawl 15 so that the pawl 15 firmly grips one of the teeth 16. Thus the pawl 15 only allows the tie strap 8 to move in one direction. If the user wishes to withdraw the strap 8 from the receiving body 10, the user must intentionally lift the latch 14 so that the pawl 15 is raised above the teeth 16.
  • a lock 60 is located on the latch 14.
  • the lock 60 prevents the movement of the tie strap 8 in any direction.
  • the lock 60 extends down from the latch 14 parallel to the sides 34.
  • Located at the end of the lock 60 is a lock hook 62.
  • Located on the sides 34 is a catch 64.
  • the lock hook 62 engages with the catch 64 as shown in Fig. 17.
  • the key 50 is releasably connected to the anchor base 4.
  • the key 50 comprises the handle 52 and the pinion 54.
  • the handle 52 is of a size that allows the user to easily grip it and apply a rotational force to the key 50.
  • the handle 52 may have several different shapes and sizes.
  • Located at the base of the key 50 is the pinion 54.
  • the pinion 54 generally has a gear-like shape and corresponds with the rack 18 located on the tie strap 8.
  • a shaft 58 is positioned between the pinion 54 and the handle 52 to raise the handle 52 above the receiving base 6.
  • the key 50 is made of any semi-rigid or rigid materials such as nylon, plastic or metal. However, other suitable materials may also be utilized such as metals.
  • an orifice 56 Located at the base of the key 50 and in the center of the pinion 54 is an orifice 56.
  • Located on the receiving base 6 is a boss 12.
  • the boss 12 has a circular shape.
  • the orifice 56 has a size and shape slightly larger than the boss 12, such that the user may place the orifice 56 over the boss 12, creating a tight fit, yet allow the user to freely turn the key 50.
  • One skilled in the art will acknowledge that there are several embodiments for releasably connecting the key 50 to the receiving base 6.
  • One such embodiment is the receiving base 6 have a recessed well in order to receive the key 50.
  • Fig. 19 and 20 which utilizes a lever 70.
  • the lever 70 releasably connects to and engages receiving body 10.
  • Located at the base of the lever 70 is a lever clasp 74.
  • the lever clasp 74 extends towards the tie strip 8 and the teeth 16.
  • the lever 70 acts as a ratchet, advancing the tie strap 8 forward with precise control.
  • the lever 70 pivots at the pivot point 72 and causes the lever clasp 74 to move.
  • the lever clasp 74 engages with one of the teeth 16 and pushes the tie strap 8 and the anchor base 4 towards the receiving base 6.
  • Fig.19 and 20 shows the lever 70 integrally formed with the receiving base 6.
  • Fig 21 shows an alternative way for the lever 70 attaching to the receiving base 6 by utilizing a Lever mortise 76.
  • One who is skilled in the art would recognize that there are several methods of creating pivot point 72 and creating a method for advancing tie strap 8.
  • a coupler 36 may connect several tissue closing devices 2 together in an array 9.
  • the coupler 36 may connect to either or both the anchor base 4 and the receiving base 6. While Fig. 3, 4, and 10 show four couplers 36 connecting each tissue closing device 2, different multiples of couplers 36 may be utilized.
  • the coupler 36 may be made from any flexible or semi-flexible material such as nylon. The flexibility, compressability or expandability of the coupler 36 allows the user to adjust the location of each tissue closing device 2. As illustrated in Fig. 6., the coupler 36 is easily severed. However, in some embodiments, the coupler 36 is rigid and resilient. In practice, an array 9 of tissue closing devices 2 are supplied to the user.
  • Fig. 4 shows a pair of scissors 38 or other cutting devices needed to separate the tissue closing device 2. If the tissue wound 100 is extremely jagged or located on a curved or rounded portion of the body, the user may separate all the tissue closing devices 2.
  • the longitudinal axis of each tissue closing device 2 is perpendicular to the longitudinal axis of the tissue wound 100 at a particular point on the tissue wound.
  • a thin film bandage 104 is position over the entire device 2 and wound 100.
  • the bandage 104 is a transparent film, but could be opaque and of various different materials.
  • the bandage 104 is to protect the wound 100 from bacteria and debris.
  • the bandage 104 prevents the device 2 from being snagged on outside objects.
  • the bandage 104 keeps the adhesive 28 more securely fastened to the skin 102. This may in turn be covered by a bulkier protective covering of various materials.
  • the method to operate the tissue wound device 2 the user removes the adhesive cover 27 from the back of the anchor base 4 and the receiving base 6.
  • the adhesive 28 connects the anchor base 4 and the receiving base 6 to the skin 102.
  • the anchor base 4 is placed next to the edge of the tissue wound 100.
  • the receiving base 6 is placed on the opposing side of the tissue wound 100.
  • the tip 24 is inserted into the slide port 30 located on the receiving base 6. However, the tip 24 may be inserted during the manufacturing process.
  • the key 50 is then inserted onto the boss 12 located on the receiving base 6. As the user turns the key 50, rotational motion of the pinion 54 is converted into a linear motion of the tie strip 8 and the anchor base 4 in such a way that the distance between the anchor base 4 and the receiving base 6 decreases.
  • the skin 102 is pulled together and closes the tissue wound 100.
  • the teeth 16 and the pawl 15 maintain the distance between the anchor base 4 and the receiving base 6. This system allows the user to carefully make incremental movements of the skin 102. Once the wound is appropriately closed, the lock 60 may be utilized to prevent any movement.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne un dispositif et des procédés sans suture pour fermer une ouverture de tissu qui réduit au minimum la main-d'oeuvre, le coût et l'habileté typiquement requis. L'appareil comprend deux ancres qui se fixent de chaque côté d'une plaie à tissu ouvert. Les deux ancres sont reliées l'une à l'autre par une bande de liaison ; la bande de liaison comporte une pluralité de dents et une crémaillère. Au fur et à mesure que les bords de la plaie et les éléments d'ancrage sont rassemblés, le système à cliquet sur la bande de liaison empêche les ancrages et le tissu enroulés de se refermer. Pour commander la distance entre les deux ancres, un système de crémaillère et de pignon et une clé ou un système de levier sont utilisés. La crémaillère est située sur la bande de liaison et le pignon est situé sur la clé.
PCT/US2018/043974 2018-07-26 2018-07-26 Dispositif et procédés sans suture de fermeture d'une ouverture de tissu WO2020023045A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2018/043974 WO2020023045A1 (fr) 2018-07-26 2018-07-26 Dispositif et procédés sans suture de fermeture d'une ouverture de tissu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2018/043974 WO2020023045A1 (fr) 2018-07-26 2018-07-26 Dispositif et procédés sans suture de fermeture d'une ouverture de tissu

Publications (1)

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WO2020023045A1 true WO2020023045A1 (fr) 2020-01-30

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3926193A (en) * 1971-12-17 1975-12-16 Harrith M Hasson Surgical closure having ease of assembly
US5879291A (en) * 1997-10-08 1999-03-09 Ethicon Endo-Surgery, Inc. Device used with a surgical retractor to elevate body parts
RU2371117C1 (ru) * 2008-03-11 2009-10-27 Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Аграрный Университет Имени Н.И. Вавилова" Устройство для сближения краев раны
US20150223814A1 (en) * 2014-02-10 2015-08-13 Alan E. Nash System for closing a wound
US20160235407A1 (en) * 2011-05-03 2016-08-18 Dermaclip Us, Llc Devices for Securely Closing Tissue Openings with Minimized Scarring
RU171432U1 (ru) * 2016-12-28 2017-05-31 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный аграрный университет имени Н.И. Вавилова" Устройство для сближения краёв раны
US20180214148A1 (en) * 2017-01-27 2018-08-02 Brett D Christiansen Sutureless device and methods for closing a tissue opening

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3926193A (en) * 1971-12-17 1975-12-16 Harrith M Hasson Surgical closure having ease of assembly
US5879291A (en) * 1997-10-08 1999-03-09 Ethicon Endo-Surgery, Inc. Device used with a surgical retractor to elevate body parts
RU2371117C1 (ru) * 2008-03-11 2009-10-27 Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Аграрный Университет Имени Н.И. Вавилова" Устройство для сближения краев раны
US20160235407A1 (en) * 2011-05-03 2016-08-18 Dermaclip Us, Llc Devices for Securely Closing Tissue Openings with Minimized Scarring
US20150223814A1 (en) * 2014-02-10 2015-08-13 Alan E. Nash System for closing a wound
RU171432U1 (ru) * 2016-12-28 2017-05-31 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный аграрный университет имени Н.И. Вавилова" Устройство для сближения краёв раны
US20180214148A1 (en) * 2017-01-27 2018-08-02 Brett D Christiansen Sutureless device and methods for closing a tissue opening

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