WO2020022975A3 - New pharmaceutical compositions in the treatment of copd - Google Patents

New pharmaceutical compositions in the treatment of copd Download PDF

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Publication number
WO2020022975A3
WO2020022975A3 PCT/TR2018/000134 TR2018000134W WO2020022975A3 WO 2020022975 A3 WO2020022975 A3 WO 2020022975A3 TR 2018000134 W TR2018000134 W TR 2018000134W WO 2020022975 A3 WO2020022975 A3 WO 2020022975A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
pharmaceutical compositions
copd
new pharmaceutical
new
Prior art date
Application number
PCT/TR2018/000134
Other languages
French (fr)
Other versions
WO2020022975A2 (en
Inventor
Mahmut Bi̇lgi̇ç
Original Assignee
Neutec Ar-Ge Sanayi Ve Ticaret Anonim Sirketi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neutec Ar-Ge Sanayi Ve Ticaret Anonim Sirketi filed Critical Neutec Ar-Ge Sanayi Ve Ticaret Anonim Sirketi
Publication of WO2020022975A2 publication Critical patent/WO2020022975A2/en
Publication of WO2020022975A3 publication Critical patent/WO2020022975A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to pharmaceutical compositions comprising N-Acetycysteine and mannitol for use in the treatment of COPD attacks.
PCT/TR2018/000134 2017-12-29 2018-12-28 New pharmaceutical compositions in the treatment of copd WO2020022975A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2017/022950 2017-12-29
TR2017/22950A TR201722950A2 (en) 2017-12-29 2017-12-29 New pharmaceutical compositions in the treatment of COPD.

Publications (2)

Publication Number Publication Date
WO2020022975A2 WO2020022975A2 (en) 2020-01-30
WO2020022975A3 true WO2020022975A3 (en) 2020-02-27

Family

ID=67901361

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2018/000134 WO2020022975A2 (en) 2017-12-29 2018-12-28 New pharmaceutical compositions in the treatment of copd

Country Status (2)

Country Link
TR (1) TR201722950A2 (en)
WO (1) WO2020022975A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116098886B (en) * 2023-01-12 2024-04-26 澳门科技大学 Pharmaceutical composition and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006030221A1 (en) * 2004-09-15 2006-03-23 Cipla Limited Pharmaceutical composition comprising a betaminetic agent and a mucolytic agent
US20070065373A1 (en) * 2003-09-15 2007-03-22 Vectura Ltd. Mucoactive agents for treating a pulmonary disease
WO2011069197A1 (en) * 2009-12-08 2011-06-16 The University Of Sydney Inhalable formulations

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065373A1 (en) * 2003-09-15 2007-03-22 Vectura Ltd. Mucoactive agents for treating a pulmonary disease
WO2006030221A1 (en) * 2004-09-15 2006-03-23 Cipla Limited Pharmaceutical composition comprising a betaminetic agent and a mucolytic agent
WO2011069197A1 (en) * 2009-12-08 2011-06-16 The University Of Sydney Inhalable formulations

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ODZIOMEK, M. ET AL.: "Conception, preparation and properties of functional carrier particles for pulmonary drug delivery", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 433, no. 1-2, 5 January 2012 (2012-01-05), pages 51 - 59, XP028493598 *
SNIJDERS, D. ET AL.: "Inhaled mucoactive drugs for treating non-cystic fibrosis bronchiectasis in children", INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, vol. 26, no. 2, pages 529 - 534, XP055687438 *
WEINBROUM, A. A. ET AL.: "Concomitant administration of mannitol and N-acetylcysteine for the prevention of lung reperfusion injury", JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, vol. 60, no. 6, 2006, pages 1290 - 1296, XP055687440 *

Also Published As

Publication number Publication date
WO2020022975A2 (en) 2020-01-30
TR201722950A2 (en) 2019-07-22

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