WO2020005892A8 - Modular biohybrid systems and methods of use thereof - Google Patents

Modular biohybrid systems and methods of use thereof Download PDF

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Publication number
WO2020005892A8
WO2020005892A8 PCT/US2019/038913 US2019038913W WO2020005892A8 WO 2020005892 A8 WO2020005892 A8 WO 2020005892A8 US 2019038913 W US2019038913 W US 2019038913W WO 2020005892 A8 WO2020005892 A8 WO 2020005892A8
Authority
WO
WIPO (PCT)
Prior art keywords
modular
systems
methods
cell
chemical energy
Prior art date
Application number
PCT/US2019/038913
Other languages
French (fr)
Other versions
WO2020005892A1 (en
Inventor
Junling GUO
Miguel Suastegui
Neel Satish JOSHI
Original Assignee
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by President And Fellows Of Harvard College filed Critical President And Fellows Of Harvard College
Priority to US17/255,757 priority Critical patent/US20210270831A1/en
Publication of WO2020005892A1 publication Critical patent/WO2020005892A1/en
Publication of WO2020005892A8 publication Critical patent/WO2020005892A8/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Nanotechnology (AREA)
  • Catalysts (AREA)
  • Inert Electrodes (AREA)

Abstract

Modular bio hybrid systems, some of which suitable for photochemical biosynthesis, are described. These systems are characterized by functionalized photocatalytic nanoparticles that are independently prepared, then assembled and attached to the modified surface of a cell, thereby enabling the cell to absorb light energy and convert it into chemical energy, for example in the form of a redox cofactor. The generated chemical energy then serves as fuel for production pathways of metabolites useful for the manufacturing of fuels, nutraceuticals, pharmaceuticals and cosmetics.
PCT/US2019/038913 2018-06-28 2019-06-25 Modular biohybrid systems and methods of use thereof WO2020005892A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US17/255,757 US20210270831A1 (en) 2018-06-28 2019-06-25 Modular biohybrid systems and methods of use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862691397P 2018-06-28 2018-06-28
US62/691,397 2018-06-28

Publications (2)

Publication Number Publication Date
WO2020005892A1 WO2020005892A1 (en) 2020-01-02
WO2020005892A8 true WO2020005892A8 (en) 2020-10-22

Family

ID=68984687

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2019/038913 WO2020005892A1 (en) 2018-06-28 2019-06-25 Modular biohybrid systems and methods of use thereof

Country Status (2)

Country Link
US (1) US20210270831A1 (en)
WO (1) WO2020005892A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113101950B (en) * 2021-04-13 2021-11-26 西南科技大学 Preparation method of surface oxidized tin disulfide nanosheet-coated tellurium nanowire for treating radioactive wastewater
CN115403139B (en) * 2022-08-09 2024-01-26 大连理工大学 Method for removing ammonia nitrogen based on optical energy driving-anaerobic ammonia oxidation process

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625835B2 (en) * 2005-06-10 2009-12-01 Gm Global Technology Operations, Inc. Photocatalyst and use thereof
WO2009078712A2 (en) * 2007-12-17 2009-06-25 Universiteit Van Amsterdam Light-driven co2 reduction to organic compounds to serve as fuels or as industrial half products by an autotroph containing a fermentative gene cassette
CN102015995B (en) * 2008-03-03 2014-10-22 焦耳无限科技公司 Engineered CO2 fixing microorganisms producing carbon-based products of interest
WO2010051325A1 (en) * 2008-10-28 2010-05-06 Ohio University A hybrid nanostructure composed of a natural photosystem and semiconductor nanoparticles
EP2920822A1 (en) * 2012-11-14 2015-09-23 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Light harvesting antenna complexes
US10047443B2 (en) * 2014-01-28 2018-08-14 University Of Rochester Methods for producing hydrogen using nanoparticle-catalyst mixtures
CA3180060A1 (en) * 2020-05-29 2021-12-02 Zongmin ZHAO Living cells engineered with polyphenol-functionalized biologically active nanocomplexes

Also Published As

Publication number Publication date
US20210270831A1 (en) 2021-09-02
WO2020005892A1 (en) 2020-01-02

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