WO2020003272A8 - An improved process for the preparation of venetoclax - Google Patents
An improved process for the preparation of venetoclax Download PDFInfo
- Publication number
- WO2020003272A8 WO2020003272A8 PCT/IB2019/055578 IB2019055578W WO2020003272A8 WO 2020003272 A8 WO2020003272 A8 WO 2020003272A8 IB 2019055578 W IB2019055578 W IB 2019055578W WO 2020003272 A8 WO2020003272 A8 WO 2020003272A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preparation
- improved process
- venetoclax
- compound
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
An improved process for the preparation of Venetoclax. The present invention also relates to an improved process for the preparation of a compound of formula I or its salts, (I) wherein R is C1-4 alkyl; and its use for the preparation of the compound of formula V.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201811024212 | 2018-06-29 | ||
ININ201811024212 | 2018-06-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2020003272A1 WO2020003272A1 (en) | 2020-01-02 |
WO2020003272A8 true WO2020003272A8 (en) | 2020-08-13 |
Family
ID=67539541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2019/055578 WO2020003272A1 (en) | 2018-06-29 | 2019-07-01 | An improved process for the preparation of venetoclax |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2020003272A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116496239A (en) * | 2022-12-14 | 2023-07-28 | 南京哈柏医药科技有限公司 | Synthesis method of key intermediate and bulk drug of vitamin Nadotox |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8546399B2 (en) | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
EP2970263B1 (en) | 2013-03-13 | 2018-05-09 | Abbvie Inc. | Processes for the preparation of an apoptosis-inducing agent |
WO2017156398A1 (en) | 2016-03-10 | 2017-09-14 | Assia Chemical Industries Ltd. | Solid state forms of venetoclax and processes for preparation of venetoclax |
WO2018029711A2 (en) | 2016-08-12 | 2018-02-15 | Mylan Laboratories Limited | Process for the preparation of venetoclax |
WO2018225043A1 (en) * | 2017-06-10 | 2018-12-13 | Lupin Limited | Solid state forms of an apoptosis-inducing agent and processes thereof |
-
2019
- 2019-07-01 WO PCT/IB2019/055578 patent/WO2020003272A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2020003272A1 (en) | 2020-01-02 |
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