WO2019244908A1

WO2019244908A1 - Composition comprising three polyglyceryl fatty acid esters

Info

Publication number: WO2019244908A1
Application number: PCT/JP2019/024178
Authority: WO
Inventors: Rui Niimi
Original assignee: L'oreal
Priority date: 2018-06-20
Filing date: 2019-06-12
Publication date: 2019-12-26
Also published as: JP2019218300A

Abstract

The present invention relates to a composition comprising: (a) at least one triglyceride oil; (b) at least one first polyglyceryl fatty acid ester having an HLB value of 3 to 7; (c) at least one second polyglyceryl fatty acid ester having an HLB value of 8 to 11; (d) at least one third polyglyceryl fatyy acid ester having an HLB value of 12 to 17; and (e) water, wherein the composition has a turbidity of 150 NTU or less, preferably 130 NTU or less and more preferably 110 NTU or less. The composition according to the present invention can reduce the amount of the polygryceryl fatty acid ester(s) therein, and therefore, the composition according to the present invnetion can be less sticky.

Description

DESCRIPTION

COMPOSITION COMPRISING THREE POLYGLYCERYL FATTY ACID ESTERS

TECHNICAL FIELD

The present invention relates to a composition, preferably a cosmetic or dermatological composition, which comprises three different types of polyglyceryl fatty acid esters.

BACKGROUND ART

Compositions including a polyglyceryl fatty acid ester have been known in the fields of cosmetics and dermatology. Polyglyceryl fatty acid esters can function as surfactants, and therefore, they may be used to prepare, typically, emulsions such as oil-in- water (O/W) or water-in-oil (W/O) emulsions. Polyglyceryl fatty acid esters are preferable in terms of environmental reasons, such as low environmental load, as compared to polyoxyethylene-based surfactants.

On the other hand, for low skin irritation and the same environmental reasons, there is a recent trend to use triglyceride oils, such as plant oils, which are more typically preferable than synthetic oils. However, it is not easy to prepare transparent emulsions including triglyceride oil(s).

Thus, there have been trials to prepare transparent emulsions including triglyceride oil and two polyglyceryl fatty acid esters. For example, J. Oleo. Sci., 63 (3) 229-237 (2014) and J. Oleo. Sci., 64 (4) 405-413 (2015) disclose methods to prepare transparent emulsions including triglyceride oil by using a combination of two different polyglyceryl fatty acid esters.

DISCLOSURE OF INVENTION

However, the above conventional methods need to use a large amount of polyglyceryl fatty acid esters, in order to prepare transparent emulsions, such that 6 times or more of polyglyceryl fatty acid esters are used as compared to the amount of triglyceride oil.

In the field of cosmetics and dermatology, the use of a large amount of polyglyceryl fatty acid ester(s) is not desirable, because this may increase sticky feeling to use caused by the polyglyceryl fatty acid ester(s).

An objective of the present invention is to provide a transparent composition which includes triglyceride oil(s) and polyglyceryl fatty acid ester(s) wherein the amount of the polygryceryl fatty acid ester(s) can be reduced.

The above objective of the present invention can be achieved by a composition comprising:

(a) at least one triglyceride oil;

(b) at least one first polyglyceryl fatty acid ester having an HLB value of 3 to 7;

(c) at least one second polyglyceryl fatty acid ester having an HLB value of 8 to 11 ;

(d) at least one third poly glyceryl fatyy acid ester having an HLB value of 12 to 17; and

(e) water,

wherein

the composition has a turbidity of 150 NTU or less, preferably 130 NTU or less, and more preferably 110 NTU or less. The (a) triglyceride oil may comprise at least one plant oil.

The amount of the (a) triglyceride oil(s) in the composition according to the present invention may range from 0.01 to 20% by weight, preferably from 0.05 to 15% by weight, and more preferably from 0.1 to 10% by weight, relative to the total weight of the composition.

The fatty acid moiety of the (b) first polyglyceiyl fatty acid ester may comprise 25 or more carbon atoms, preferably 30 or more carbon atoms, and more preferably 35 or more carbon atoms.

The (b) first polyglyceryl fatty acid ester may comprise 2 to 10 glycerol units, preferably 3 to 9 glycerol units, and more preferably 4 to 8 glycerol units.

The weight ratio of the amount of the (b) first polyglyceryl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition according to the present invention may range from 0.6 to 1.3, preferably from 0.7 to 1.2, and more preferably from 0.8 to 1.1.

The fatty acid moiety of the (c) second polyglyceiyl fatty acid ester may comprise 8 to 18 carbon atoms, preferably 9 to 16 carbon atoms, and more preferably 10 to 14 carbon atoms.

The (c) second polyglyceiyl fatty acid ester may comprise 2 to 10 glycerol units, preferably 3 to 8 glycerol units, and more preferably 4 to 6 glycerol units.

The amount of the (c) second polyglyceiyl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition according to the present invention may range from 0.5 to 1.3, preferably from 0.6 to 1.2, and more preferably from 0.7 to 1.1.

The fatty acid moiety of the (d) third polyglyceiyl fatty acid ester may comprise 12 or less carbon atoms, preferably 11 or less carbon atoms, and more preferably 10 or less carbon atoms.

The (d) third polyglyceiyl fatty acid ester may comprise 2 to 10 glycerol units, preferably 3 to 8 glycerol units, and more preferably 4 to 6 glycerol units.

The weight ratio of the amount of the (d) third polyglyceiyl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition according to the present invention may range from 0.1 to 1.1 , preferably from 0.2 to 1.0, and more preferably from 0.3 to 0.9.

The weight ratio of (the total amounts of the (b) first polyglyceiyl fatty acid ester(s), the (c) second polyglyceiyl fatty acid ester(s) and the (d) third polyglyceiyl fatty acid ester(s))/the amount of the (a) triglyceride oil(s) may be 3.0 or less, preferably 2.5 or less, and more preferably 2.0 or less.

The composition according to the present invention may be in the form of an emulsion, a preferably an O/W emulsion, and more preferably an O/W nano- or micro-emulsion.

The particle size of the (a) triglyceride oil may be 35 nm or less, preferably 30 nm or less, and more preferably 25 nm or less.

The present invention also relates to a cosmetic process for treating a keratin substance, comprising the step of applying the composition according to the present invention to the keratin substance.

BEST MODE FOR CARRYING OUT THE INVENTION After diligent research, the inventors have discovered that it is possible to provide a transparent composition which includes triglyceride oil(s) and polyglyceryl fatty acid ester(s) wherein the amount of the polygryceryl fatty acid ester(s) can be reduced, by using a combination of three different types of polyglyceryl fatty acid esters.

The composition according to the present invention may be characterized by a combination of: at least one first polyglyceryl fatty acid ester having a lower HLB value;

at least one second polyglyceryl fatty acid ester having a medium HLB value; and

at least one third polyglyceryl fatyy acid ester having a higher HLB value.

The lower HLB value of the first polyglycderyl fatty acid ester may belong to a lower HLB numerical range,

the medium HLB value of the second polyglyceryl fatty acid ester may belong to a medium HLB numerical range,

the higher HLB value of the third polyglyceryl fatty acid ester may belong to a higher HLB numerical range,

and

the lower HLB numerical range, the medium HLB numerical range and the higher HLB numerical range may not overlap each other.

Thus, one aspect of the present invention is a composition comprising:

(a) at least one triglyceride oil;

(d) at least one third polyglyceryl fatyy acid ester having an HLB value of 12 to 17; and

(e) water,

wherein

the composition has a turbidity of 150 NTU or less, preferably 130 NTU or less, and more preferably 110 NTU or less.

The composition according to the present invention is transparent such that it has a turbidity of 150 NTU or less, preferably 130 NTU or less, and more preferably 110 NTU or less.

In the composition according to the present invention the amount of the polyglyceryl fatty acid esters can be reduced or limited. Therefore, the composition according to the present invention can provide no sticky feeling or reduced sticky feeling to the touch. Therefore, the composition according to the present invention can provide an excellent feel during use, in particular on feeling of the skin after application of the composition.

The term“sticky” here means a property which provides a tacky feeling to the skin.

The composition according to the present invention may be prepared without a large amount of energy, e.g., using a homogenizer. Thus, the composition according to the present invention may be prepared by using a small amount of energy such as gently stirring the ingredients of the composition. Therefore, the composition according to the present invention is environmental friendly in view of preparation approach thereof.

Hereinafter, the composition according to the present invention will be explained in a more detailed manner. [Triglyceride Oil]

The composition according to the present invention comprises (a) at least one triglyceride oil. A single type of trigyceride oil may be used, but two or more different types of triglyceride oils may be used in combination.

Here,“oil” means a fatty compound or substance which is in the form of a liquid or a paste (non-solid) at room temperature (25°C) under atmospheric pressure (760 mmHg). As the (a) triglyceride oil(s), those generally used in cosmetics can be used alone or in combination thereof. ITiese oils may be volatile or non-volatile.

The presence of the (a) triglyceride oil may provide a moisturizing effect or emollient effect after washing the keratinous substance, in particular skin.

The (a) triglyceride oil comprises at least one triglyceride. The triglyceride may be referred to as a triacyl glycerol, and three fatty acids and one glycerol are esterified in the triglyceride.

The fatty acid may have, for example, 4 or more, 6 or more, 8 or more, or 10 or more carbon atoms, and 30 or less, 28 or less, 26 or less, or 24 or less carbon atoms. The fatty acid may have different carbon chain length of, for example, from 4 to 30 carbon atoms, more preferably from 6 to 28 carbon atoms, more preferably from 8 to 26 carbon atoms, and even more preferably from 10 to 24 carbon atoms. The carbon chain may be linear or branched.

The fatty acid may be saturated or unsaturated.

As examples of the saturated fatty acids, mention may be made of, for example, palmitic acid, heptadecanoic acid, stearic acid, nonadecanoic acid, arachidic acid, behenic acid, tetradocosanoic acid, hexadocosanoic acid, and octadocosanoic acid.

As examples of the unsaturated fatty acids, mention may be made of, for example, palmitoleic acid, oleic acid, elaidic acid, vaccenic acid, gadoleic acid, eicosenoic acid, erucic acid, nervonic acid, linoleic acid, eicosadienoic acid, docosadienoic acid, linolenic acid, pinolenic acid, eleostearic acid, mead acid, eicosatrienoic acid, stearidonic acid, arachidonic acid, eicosatetraenoic acid, adrenic acid, bosseopentaenoic acid, eicosapentaenoic acid, osbond acid, clupanodonic acid, tetracosapentaenoic acid, docosahexaenoic acid, and nisinic acid.

The (a) triglyceride oil which is suitable for the present invention is of plant origin. In other words, it is preferable that the (a) triglyceride oil comprise at least one plant oil. It is more preferable that the (a) triglyceride oil be selected from plant oils.

The plant oil may be selected from plant-extracted oils, plant-extracted butters, and mixtures thereof.

Among the plant-extracted oils, the following may be cited: jojoba oil, babassu oil, sunflower oil, olive oil, canola oil, coconut oil, meadowfoam seed oil; Brazil nut oil, marula oil, maize oil, argan oil, soybean oil, marrow oil, grapeseed oil, linseed oil, sesame oil, hazelnut oil, apricot oil, macadamia oil, arara oil, coriander oil, castor oil, avocado oil, shea butter oil, rapeseed oil, and copra oil. Among the plant-extracted butters, the following may be cited: shea butter, Nilotica shea butter (Butyrospermum parkii), galam butter (Butyrospermum parkii), Borneo butter or fat or tengkawang tallow (Shorea stenoptera), shorea butter, illipe butter, madhuca butter or (Bassia) Madhuca longifolia butter, mowrah butter (Madhuca latifolia), katiau butter (Madhuca mottleyana), phulwara butter (M. butyracea), mango butter (Mangifera indica), murumuru butter (Astrocaryum murumuru), kokum butter (Garcinia indica), ucuuba butter (Virola sebifera), tucuma butter, painya (kpangnan) butter (Pentadesma butyracea), coffee butter (Coffea arabica), apricot butter (Prunus armeniaca), macadamia butter (Macadamia temifolia), grapeseed butter (Vitis vinifera), avocado butter (Persea gratissima), olive butter (Olea europaea), sweet almond butter (Prunus amygdalus dulcis), cocoa butter (Theobroma cacao), and sunflower butter.

More preferably, the (a) triglyceride oil may be selected from soybean oil, coconut oil, sunflower oil, argan oil and olive oil.

The amount of the (a) triglyceride oil(s) in the composition according to the present invention may be 0.01% by weight or more, preferably 0.05% by weight or more, and more preferably 0.1% by weight or more, relative to the total weight of the composition.

On the other hand, the amount of the (a) triglyceride oil(s) in the composition according to the present invention may be 20% by weight or less, preferably 15% by weight or less, and more preferably 10% by weight or less, relative to the total weight of the composition.

The amount of the (a) triglyceride oil(s) in the composition according to the present invention may range from 0.01 to 20% by weight, preferably from 0.05 to 15% by weight, more preferably from 0.1 to 10% by weight, relative to the total weight of the composition.

[First Polyglyceiyl Fatty Acid Ester]

The composition according to the present invention comprises (b) at least one first polyglyceryl fatty acid ester having an HLB value of 3 to 7. A single type of (b) first polyglyceryl fatty acid ester may be used, but two or more different types of (b) first polyglyceiyl fatty acid ester may be used in combination.

The (b) first polyglyceryl fatty acid ester can function as a surfactant, in particular a nonionic surfactant.

The (b) first polyglyceiyl fatty acid may have an HLB value of 3.0 to 7.0, preferably 3.1 to 6.0, more preferably 3.2 to 5.0, and even more preferably 3.3 to 4.0.

The term HLB ("hydrophilic-lipophilic balance") is well known to those skilled in the art, and reflects the ratio between the hydrophilic part and the lipophilic part in the molecule.

If two or more (b) first polyglyceryl fatty acid esters are used, the HLB value is determined by the weight average of the HLB values of all the (b) first polyglyceiyl fatty acid esters.

The (b) first polyglyceryl fatty acid ester may be chosen from mono, di, tri and more esters of saturated or unsaturated fatty acid(s).

The fatty acid moiety of the (b) first polyglyceiyl fatty acid ester may comprise 25 or more carbon atoms, preferably 30 or more carbon atoms, and more preferably 35 or more carbon atoms. The faty acid moiety of the (b) first polyglyceryl fatty acid ester may comprise 90 or less carbon atoms, preferably 72 or less carbon atoms, and more preferably 54 or less carbon atoms. The fatty acid moiety of the (b) first polyglyceryl fatty acid ester may have carbon atoms of from 25 to 90, preferably from 30 to 72, and more preferably from 35 to 54 carbon atoms.

The fatty acid moiety of the (b) first polyglyceryl fatty acid ester may be a polymer of saturated or unsaturated fatty acids. If the fatty acid has a carboxylic group and a hydroxyl group, the polymer may be a polycondensate of the fatty acids which can be formed by the reaction of the carboxylic group or the hydroxyl group of one fatty acid and the hydroxyl group and the carboxylic acid of another fatty acid, respectively. Thus, the fatty acid moiety of the (b) first polyglyceryl fatty acid ester may be a polycondensate of saturated or unsaturated hydroxyacids.

In other words, the (b) first polyglyceryl fatty acid ester may be a polyglyceryl ester, preferably a polyglyceryl monoester, of a polycondensate of saturated or unsaturated hydroxylacids.

Ricinoleic acid is an example of hydroxyl acids, in particular unsaturated hydroxylacids, and has a carboxylic group and a hydroxyl group. Thus, the fatty acid moiety of the (b) first polyglyceryl fatty acid may be formed by the polycondensation of ricinoleic acids, which results in

polyricinoleate. Thus, the (b) first polyglyceryl fatty acid ester may be polyglycerol

polyricinoleate (PGPR), i.e., a polyglyceryl ester, preferably a polyglyceryl monoester, of polyricinoleate.

The (b) first polyglyceryl fatty acid ester(s) may be selected from the group consisting of PG3 polyricinoleate, PG4 polyricinoleate, PG5 polyricinoleate, PG6 polyricinoleate (HLB: 3.5), and mixtures thereof.

Alternatively, the fatty acid for the fatty acid moiety or the fatty acid moiety of the (b) first polyglyceryl fatty acid ester may include 4 to 24 carbon atoms, preferably 6 to 22 carbon atoms, and more preferably 8 to 20 carbon atoms.

The fatty acid for the fatty acid moiety of the (b) first polyglyceryl fatty acid ester may be saturated or unsaturated, and may be selected from lauric acid, myristic acid, stearic acid, isostearic acid, and oleic acid.

It is preferable that the (b) first polyglyceiyl fatty acid ester comprises 2 to 10 glycerol units, preferably 3 to 9 glycerol units, and more preferably 4 to 8 glycerol units.

The (b) first polyglyceryl fatty acid ester(s) may be selected from the group consisting of PG2 stearate (HLB: 5.0), PG2 distearate (HLB: 4), PG2 isostearate (HLB: 4.7), PG2 diisostearate (HLB: 3.2), PG2 triisostearate (HLB: 3), PG2 sesquiisostearate (HLB: about 4), PG2 oleate (HLB: 5.5), PG2 sesquioleate (HLB: 5.3), PG3 distearate (HLB: 5), PG3 diisostearate (HLB: 5), PG3 dicocoate (HLB: 7), PG5 hexastearate (HLB: 4.0), PG5 trioleate (HLB: 7.0), PG10 pentaoleate (HLB: 6.4), and mixtures thereof.

The amount of the (b) first polyglyceiyl fatty acid ester(s) in the composition according to the present invention may be 0.01% by weight or more, preferably 0.05% by weight or more, and more preferably 0.1% by weight or more, relative to the total weight of the composition.

On the other hand, the amount of the (b) first polyglyceryl fatty acid ester(s) in the composition according to the present invention may be 20% by weight or less, preferably 15% by weight or less, and more preferably 10% by weight or less, relative to the total weight of the composition. The amount of the (b) first polyglyceiyl fatty acid ester(s) in the composition according to the present invention may range from 0.01 to 20% by weight, preferably from 0.05 to 15% by weight, more preferably from 0.1 to 10% by weight, relative to the total weight of the composition.

The weight ratio of the amount of the (b) first polyglyceiyl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition according to the present invention may range from 0.6 to 1.3, preferably from 0.7 to 1.2, and more preferably from 0.8 to 1.1. [Second Polyglyceiyl Fatty Acid Ester]

The composition according to the present invention comprises (c) at least one second polyglyceryl fatty acid ester having an HLB value of 8 to 11. A single type of (c) second polyglyceiyl fatty acid ester may be used, but two or more different types of (c) second polyglyceiyl fatty acid ester may be used in combination.

The (c) second polyglyceiyl fatty acid ester can function as a surfactant, in particular a nonionic surfactant. The (c) second polyglyceiyl fatty acid may have an HLB value of 8.0 to 11.0, preferably 9.0 to 11.0, more preferably 9.5 to 11.0, and even more preferably 10.0 to 11.0.

If two or more (c) second polyglyceiyl fatty acid esters are used, the HLB value is determined by the weight average of the HLB values of all the (c) second polyglyceryl fatty acid esters.

The (c) second polyglyceiyl fatty acid ester may be chosen from mono, di, tri and more esters of saturated or unsaturated fatty acid(s).

The fatty acid for the fatty acid moiety or the fatty acid moiety of the (c) second polyglyceryl fatty acid ester may include 8 to 18 carbon atoms, preferably 9 to 16 carbon atoms, and more preferably 10 to 14 carbon atoms.

The fatty acid for the fatty acid moiety of the (c) second polyglyceryl fatty acid ester may be saturated or unsaturated, and may be selected from caprylic acid, capric acid, lauric acid, myristic acid, stearic acid, isostearic acid, and oleic acid.

It is preferable that the (c) second polyglyceiyl fatty acid ester comprises 2 to 10 glycerol units, preferably 3 to 8 glycerol units, and more preferably 4 to 6 glycerol units. The (c) second polyglyceiyl fatty acid ester(s) may be selected from the group consisting of PG2 sesquicaprylate (HLB: about 8), PG2 caprate (HLB: 9.5), PG2 laurate (HLB: 8.5), PG4 oleate (HLB: 8.8), PG4 laurate (HLB: 10.3), PG4 isostearate (HLB: 8.2), PG5 laurate (HLB: 10.5), PG6 isostearate (HLB: 10.8), PG6 distearate (HLB: 8), PG10 trilaurate (HLB: 10.4), PG10 distearate (HLB: about 9), PG10 tristearate (HLB: 8), PG10 diisostearate (HLB: 10), PG10 triisostearate (HLB: 8), PG10 dioleate (HLB: about 11), PG10 tricocoate (HLB: 9), and mixtures thereof.

The amount of the (c) second polyglyceryl fatty acid ester(s) in the composition according to the present invention may be 0.01% by weight or more, preferably 0.05% by weight or more, and more preferably 0.1% by weight or more, relative to the total weight of the composition. On the other hand, the amount of the (c) second polyglyceryl fatty acid ester(s) in the composition according to the present invention may be 20% by weight or less, preferably 15% by weight or less, and more preferably 10% by weight or less, relative to the total weight of the composition.

The amount of the (c) second polyglyceryl fatty acid ester(s) in the composition according to the present invention may range from 0.01 to 20% by weight, preferably from 0.05 to 15% by weight, more preferably from 0.1 to 10% by weight, relative to the total weight of the composition.

The weight ratio of the amount of the (c) second polyglyceryl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition according to the present invention may range from 0.5 to 1.3, preferably from 0.6 to 1.2, and more preferably from 0.7 to 1.1.

[Third Polyglyceiyl Fatty Acid Ester]

The composition according to the present invention comprises (d) at least one third polyglyceiyl fatty acid ester having an HLB value of 12 to 17. A single type of (d) third polyglyceiyl fatty acid ester may be used, but two or more different types of (d) third polyglyceryl fatty acid ester may be used in combination.

The (d) third polyglyceryl fatty acid ester can function as a surfactant, in particular a nonionic surfactant.

The (d) third polyglyceiyl fatty acid may have an HLB value of 12.0 to 17.0, preferably 12.5 to 16.0, more preferably 13.0 to 15.0, and even more preferably 13.5 to 14.5.

If two or more (d) third polyglyceiyl fatty acid esters are used, the HLB value is determined by the weight average of the HLB values of all the (d) third polyglyceiyl fatty acid esters.

The (d) third polyglyceryl fatty acid ester may be chosen from mono, di, tri and more esters of saturated or unsaturated fatty acid(s).

The fatty acid for the fatty acid moiety or the fatty acid moiety of the (d) third polyglyceiyl fatty acid ester may comprise 4 or more carbon atoms, preferably 6 or more carbon atoms, and more preferably 8 or more carbon atoms. The fatty acid for the fatty acid moiety or the fatty acid moiety of the (d) third polyglyceryl fatty acid ester may comprise 12 or less carbon atoms, preferably 11 or less carbon atoms, and more preferably 10 or less carbon atoms. The fatty acid for the fatty acid moiety or the fatty acid moiety of the (d) third polyglyceryl fatty acid ester may have carbon atoms of from 4 to 12, preferably from 6 to 11, and more preferably from 8 to 10 carbon atoms.

The fatty acid for the fatty acid moiety of the (d) third polyglyceryl fatty acid ester may be saturated or unsaturated, and may be selected from caprylic acid, capric acid, lauric acid, myristic acid, stearic acid, isostearic acid, and oleic acid.

It is preferable that the (d) third polyglyceiyl fatty acid ester comprises 2 to 10 glycerol units, preferably 3 to 8 glycerol units, and more preferably 4 to 6 glycerol units.

The (d) third polyglyceiyl fatty acid ester(s) may be selected from the group consisting of PG3 cocoate (HLB: 12), PG3 caprate (HLB: about 14), PG4 caprylate (HLB: 14), PG4 caprate (about 15), PG5 myristate (HLB: 15.4), PG5 stearate (HLB: 15), PG5 oleate (HLB: 12.2), PG6 caprylate (HLB: 14.6), PG6 caprate (HLB: 13.1), PG6 laurate (HLB: 14.1), PG10 laurate (HLB: 15.2), PG10 myristate (HLB: 14.9), PG10 dimyristate (HLB: 12.3), PG10 stearate (HLB: 14.1), PG10 isostearate (HLB: 13.7), PG10 oleate (HLB: 13.0), PG10 sesquistearate (HLB: 12), PG10 cocoate (HLB: 16), PG10 dicocoate (HLB: 12), and mixtures thereof.

The amount of the (d) third polyglyceryl fatty acid ester(s) in the composition according to the present invention may be 0.01% by weight or more, preferably 0.05% by weight or more, and more preferably 0.1% by weight or more, relative to the total weight of the composition.

On the other hand, the amount of the (d) third polyglyceiyl fatty acid ester(s) in the composition according to the present invention may be 20% by weight or less, preferably 15% by weight or less, and more preferably 10% by weight or less, relative to the total weight of the composition.

The amount of the (d) third polyglyceryl fatty acid ester(s) in the composition according to the present invention may range from 0.01 to 20% by weight, preferably from 0.05 to 15% by weight, and more preferably from 0.1 to 10% by weight, relative to the total weight of the composition.

The weight ratio of the amount of the (d) third polyglyceryl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition according to the present invention may range from 0.1 to 1.1, preferably from 0.2 to 1.0, and more preferably from 0.3 to 0.9.

[Amount of Polyglyceiyl F atty Acid Ester(s)]

According to the present invention, the weight ratio of (the total amounts of the (b) first polyglyceiyl fatty acid ester(s), the (c) second polyglyceryl fatty acid ester(s) and the (d) third polyglyceryl fatty acid ester(s))/the amount of the (a) triglyceride oil(s) may be 3.0 or less, preferably 2.5 or less, and more preferably 2.0 or less.

In conventional art, the weight ratio of the amount(s) of glyceryl fatty acid ester(s)/the triglyceride oil(s) is much higher than 3.0, such as 6.0.

Therefore, the composition according to the present invention can reduce or limit the total amounts of the polyglyceiyl fatty acid esters.

As the present invention can reduce the total amounts of the poly glyceryl fatty acid esters, the composition according to the present invention can provide no sticky feeling or a reduced sticky feeling to the touch.

It may be preferable that the weight ratio of (the total amounts of the (b) first polyglyceryl fatty acid ester(s), the (c) second polyglyceryl fatty acid ester(s), and the (d) third polyglyceryl fatty acid ester(s))/the amount of the (a) triglyceride oil(s) be more than 1.5, preferably more than 1.6, and more preferably more than 1.7.

[Water]

The composition according to the present invention comprises (e) water.

The amount of the (e) water in the composition according to the present invention may be 60% by weight or more, preferably 70% by weight or more, and more preferably 80% by weight or more, relative to the total weight of the composition. It may be even more preferable that the amount of water in the composition according to the present invention be 90% by weight or more, relative to the total weight of the composition.

On the other hand, the amount of the (e) water in the composition according to the present invention may be 99% by weight or less, preferably 98% by weight or less, and more preferably 97% by weight or less, relative to the total weight of the composition. It may be even more preferable that the amount of water in the composition according to the present invention be 96% by weight or less, relative to the total weight of the composition.

The amount of (e) water in the composition according to the present invention may range from 60% to 99% by weight, preferably from 70% to 98% by weight, more preferably from 80% to 97% by weight, relative to the total weight of the composition. It may be even more preferable that the amount of water in the composition according to the present invention be from 90% to 96% by weight, relative to the total weight of the composition.

[Polyol]

The composition according to the present invention may further comprise at least one polyol. A single type of polyol may be used, but two or more different types of polyol may be used in combination.

The term“polyol” here means an alcohol having two or more hydroxy groups, and does not encompass a saccharide or a derivative thereof. The derivative of a saccharide includes a sugar alcohol which is obtained by reducing one or more carbonyl groups of a saccharide, as well as a saccharide or a sugar alcohol in which the hydrogen atom or atoms in one or more hydroxy groups thereof has or have been replaced with at least one substituent such as an alkyl group, a

hydroxyalkyl group, an alkoxy group, an acyl group or a carbonyl group.

The polyol may be a C₂-C _l2 polyol, preferably a C₂-C9 polyol, comprising at least 2 hydroxy groups, and preferably 2 to 5 hydroxy groups.

The polyol may be a natural or synthetic polyol. The polyol may have a linear, branched or cyclic molecular structure.

The polyol may be selected from glycerins and derivatives thereof, and glycols and derivatives thereof. The polyol may be selected from the group consisting of glycerin, diglycerin, polyglycerin, ethyleneglycol, diethyleneglycol, propyleneglycol, dipropyleneglycol, butyleneglycol, pentyleneglycol, hexyleneglycol, 1, 3-propanediol, l,5-pentanediol, polyethyleneglycol (5 to 50 ethyleneoxide groups), and sugars such as sorbitol.

The amount of the polyol(s) in the composition according to the present invention may be 0.01% by weight or more, preferably 0.05% by weight or more, and more preferably 0.1% by weight or more, relative to the total weight of the composition.

On the other hand, the amount of the polyol(s) in the composition according to the present invention may be 15% by weight or less, preferably 10% by weight or less, and more preferably 5% by weight or less, relative to the total weight of the composition.

Thus, the polyol(s) may be present in the composition according to the present invention in an amount ranging from 0.01% to 15% by weight, and preferably from 0.05% to 10% by weight, such as from 0.1% to 5% by weight, relative to the total weight of the composition.

[Other Ingredients] The composition according to the present invention may contain one or more monoalcohols which are in the form of a liquid at room temperature (25°C), such as for example linear or branched monoalcohols comprising from 1 to 6 carbon atoms, such as ethanol, propanol, butanol, isopropanol, isobutanol, pentanol, and hexanol. The amount of the monoalcohol(s) in the composition according to the present invention may be

0.01 % by weight or more, preferably 0.1 % by weight or more, and more preferably 1 % by weight or more, relative to the total weight of the composition.

On the other hand, the amount of the monoalcohol(s) in the composition according to the present invention may be 15% by weight or less, preferably 10% by weight or less, and more preferably 5% by weight or less, relative to the total weight of the composition.

Thus, the amount of the monoalcohol(s) in the composition according to the present invention may range from 0.01% to 15% by weight, preferably from 0.1% to 10% by weight, and more preferably from 1 % to 5% by weight, relative to the total weight of the composition.

The composition according to the present invention may also include various adjuvants conventionally used in cosmetic and dermatological compositions, such as anionic, non-ionic, cationic, and amphoteric or zwitterionic polymers, anionic, non-ionic, cationic, and amphoteric surfactants, antioxidants, coloring agents, chelating agents, sequestering agents, fragrances, dispersing agents, conditioning agents, film-forming agents, preservatives, co-preservatives, and mixtures thereof, except for the ingredients as explained above.

The composition according to the present invention may contain polyoxyethylene-based nonionic surfactant or synthetic oil. However, it is preferable that the amount of the

polyoxyethylene-based nonionic surfactant or synthetic oil be limited such that it is less than 1% by weight, more preferably less than 0.1% by weight, and even more preferably less than 0.01% by weight, relative to the total weight of the composition. It is most preferable that the composition according to the present invention comprises no polyoxyethylene-based nonionic surfactant or synthetic oil.

(Preparation)

The composition according to the present invention can be prepared by mixing the essential ingredient(s) as explained above, and optional ingredient(s), if necessary, as explained above.

The method and means to mix the above essential and optional ingredients are not limited. Any conventional method and means can be used to mix the above essential and optional ingredients to prepare the composition according to the present invention.

The composition according to the present invention may be prepared without a large amount of energy, e.g., using a homogenizer. Thus, the composition according to the present invention may be prepared by using a small amount of energy such as gently stirring the ingredients of the composition. Therefore, the composition according to the present invention is environmental friendly in view of preparation approach thereof. [Form]

The form of the composition according to the present invention is not particularly limited, and may take various forms such as an emulsion (O/W or W/O form), an aqueous gel, an aqueous solution, or the like.

It is preferable that the composition according to the present invention be in the form of an emulsion. It is more preferable that the composition according to the present invention be in the form of an O/W emulsion which comprises oil phases dispersed in a continuous aqueous phase. The dispersed oil phases can be oil droplets in the aqueous phase.

The O/W architecture or structure, which consists of oil phases dispersed in an aqueous phase, has an external aqueous phase, and therefore if the composition according to the present invention has the O/W architecture or structure, it can provide a pleasant feeling during use because of the feeling of immediate freshness that the aqueous phase can provide.

It is preferable that the composition according to the present invention be in the form of a nano- or micro-emulsion.

The "micro-emulsion" may be defined in two ways, namely, in a broad sense and in a narrow sense. That is to say, there is the one case ("micro-emulsion in the narrow sense") in which the micro-emulsion refers to a thermodynamically stable isotropic single liquid phase containing a ternary system having three ingredients of an oily component, an aqueous component and a surfactant, and there is the other case ("micro-emulsion in the broad sense") in which among thermodynamically unstable typical emulsion systems the micro-emulsion additionally includes those such emulsions presenting transparent or translucent appearances due to their smaller particle sizes (Satoshi Tomomasa, et al., Oil Chemistry, Yol. 37, No. 11 (1988), pp. 48-53). The "micro-emulsion" as used herein refers to a "micro-emulsion in the narrow sense", i.e., a thermodynamically stable isotropic single liquid phase.

The micro-emulsion refers to either one state of an O/W (oil-in- water) type microemulsion in which oil is solubilized by micelles, a W/O (water-in-oil) type microemulsion in which water is solubilized by reverse micelles, or a bicontinuous microemulsion in which the number of associations of surfactant molecules are rendered infinite so that both the aqueous phase and oil phase have a continuous structure.

The micro-emulsion may have a dispersed phase with a particle size of 100 nm or less, preferably 50 nm or less, and more preferably 20 nm or less, measured by laser granulometry.

The“nano-emulsion” here means an emulsion characterized by a dispersed phase with a size of less than 350 nm, the dispersed phase being stabilized by a crown of the (b) to (d) nonionic surfactants that may optionally form a liquid crystal phase of lamellar type, at the dispersed phase/continuous phase interface. In the absence of specific opacifiers, the transparency of the nano-emulsions arises from the small size of the dispersed phase, this small size being obtained by virtue of the use of mechanical energy.

Nanoemulsions can be distinguished from microemulsions by their structure. Specifically, micro-emulsions are thermodynamically stable dispersions formed from, for example, micells which are formed by the ingredients (b) to (d) and swollen with the ingredient (a). Furthermore, microemulsions do not require substantial mechanical energy in order to be prepared.

The nano-emulsion may have a dispersed phase with a particle size of 300 nm or less, preferably 200 nm or less, and more preferably 100 nm or less, measured by laser granulometry.

The composition according to the present invention may be in the form of an O/W nano- or micro-emulsion, a W/O nano- or micro-emulsion or a bicontinuous emulsion. It is preferable that the composition according to the present invention be in the form of an O/W nano- or micro-emulsion. It is more preferable that the composition according to the present invention be in the form of an O/W nano- or micro-emulsion. It is even more preferable that the particle size of the (a) triglyceride oil be 35 nm or less, preferably 30 nm or less, and more preferably 25 nm or less. The particle size can be measured by a dynamic light scattering method. The particle size measurement can be performed by, for example, the Particle Size Analyzer ELSZ-2000 series, marketed by Otsuka Electronics Co., Ltd.

The particle size can be a volume-average particle diameter or a number-average particle diameter, preferably a volume-average particle diameter.

The composition according to the present invention is transparent.

The transparency may be measured by measuring the turbidity (for example, turbidity can be measured with a 2100Q (marketed by Hach Company) having a round cell (25 mm in diameter and 60 mm height) and a tungsten filament lamp which can emit visible light (between 400 and 800 nm, preferably from 400 to 500 nm). The measurement can be performed on the undiluted composition. The blank may be determined with distilled water.

The composition according to the present invention has a turbidity of 150 NTU or less, preferably 130 NTU or less and more preferably 110 NTU or less.

[Process and Use]

It is preferable that the composition according to the present invention be a cosmetic or

dermatological composition, preferably a cosmetic composition, and more preferably a cosmetic composition for a keratin substance such as skin.

The composition according to the present invention can be used for a non-therapeutic process, such as a cosmetic process, for treating a keratin substance such as skin, hair, mucous membranes, nails, eyelashes, eyebrows and/or scalp, by being applied to the keratin substance.

Thus, the present invention also relates to a cosmetic process for treating a keratin substance, comprising the step of applying the composition according to the present invention to the keratin substance.

The present invention may also relate to a use of the composition according to the present invention as a cosmetic product or in a cosmetic product such as care products, washing products, make-up products, make-up-removing products, for body and/or facial skin and/or mucous membranes and/or the scalp and/or the hair and/or the nails and/or the eyelashes and/or the eyebrows.

In other words, the composition according to the present invention can be used, as it is, as a cosmetic product. Alternatively, the composition according to the present invention can be used as an element of a cosmetic product. For example the composition according to the present invention can be added to or combined with any other elements to form a cosmetic product.

The care product may be a lotion, a cream, a hair tonic, a hair conditioner, a sun screening agent, and the like. The washing product may be a shampoo, a face wash, a hand wash and the like. The make-up product may be a foundation, a mascara, a lipstick, a lip gloss, a blusher, an eye shadow, a nail varnish, and the like. The make-up-removing product may be a make-up cleansing agent and the like.

Another aspect of the present invention relates to a use of:

(c) at least one second polyglyceryl fatty acid ester having an HLB value of 8 to 11; and

(d) at least one third polyglyceryl fatyy acid ester having an HLB value of 12 to 17 for the manufacture of a composition with a turbidity of 150 NTU or less, preferably 130 NTU or less, and more preferably 110 NTU or less comprising

(a) at least one triglyceride oil, and

(e) water.

Another aspect of the present invention also relates to a process for preparing a composition with a turbidity of 150 NTU or less, preferably 130 NTU or less, and more preferably 110 NTU or less comprising a step of mixing:

(a) at least one triglyceride oil;

(b) at least one first poly glyceryl fatty acid ester having an HLB value of 3 to 7;

(c) at least one second polyglyceryl fatty acid ester having an HLB value of 8 to 11 ; and

(d) at least one third polyglyceryl fatyy acid ester having an HLB value of 12 to 17

(e) water.

It is preferable that the mixing step be performed by a so-called low energy process without a special mechanical stirrer, such as a homogenizer, using a large amount of energy. The low energy process can be performed by simply gentling the ingredients (a) to (e).

It is preferable that the composition be in the form of an emulsion, more preferably an O/W emulsion, and even more preferably an O/W nano- or micro-emulsion.

The present invention also relates to a use of:

(d) at least one third polyglyceryl fatyy acid ester having an HLB value of 12 to 17 in an O/W emulsion comprising

(a) at least one triglyceride oil, and

(e) water,

in order to make oil droplets of the (a) triglyceride oil have a particle size of 35 nm or less, preferably 30 nm or less, and more preferably 25 nm or less.

The present invention also relates to a process for making oil droplets of (a) triglyceride oil in an O/W emulsion comprising the (a) triglyceride and (e) water have a particle size of 35 nm or less, preferably 30 nm or less, and more preferably 25 nm or less, comprising a step of adding to the emulsion or using in the emulsion:

(d) at least one third polyglyceryl fatyy acid ester having an HLB value of 12 to 17. The above explanations regarding the ingredients (a) to (e), as well as the optional ingredients, for the composition according to the present invention can apply to those for the uses and processes according to the present invention. The explanations regarding the preparation and forms of the composition according to the present invention can also apply to those of the composition recited in the above uses and processes.

EXAMPLES The present invention will be described in more detail by way of examples which however should not be construed as limiting the scope of the present invention.

[Examples 1-9 and Comparative Examples 1-3] The following compositions according to Examples 1 -9 and Comparative Examples 1 -3 , shown in Table 1 , were prepared by mixing the components shown in Table 1 as follows:

(1) gently mixing the ingredients of Phase A at about 70°C to form a uniform mixture of Phase A ingredients;

(2) cooling the mixture of Phase A ingredients to about 30°C or less; and

(3) adding the mixture of Phase A ingredients to the Phase B under gentle mixing.

The compositions according to Examples 1-9 and Comparative Examples 1-3 were in the form of an O/W emulsion. The numerical values for the amounts of the components shown in Table 1 are all based on“% by weight” as active raw materials.

[Evaluations]

(Turbidity)

The turbidity of the O/W emulsions according to Examples 1-9 and Comparative Examples 1-3 was measured at room temperature by using a trubidimeter (2100Q portable, Hach Company).

The results are shown in Table 1 as“NTU”. The smaller the NTU value is, the more transparent the composition is.

The results are shown in Table 1.

(Particle Size)

The particle size (nm) of the oil droplets in the O/W emulsions according to Examples 1-9 and Comparative Examples 1-3 was measured by the Particle Size Analyzer ELSZ-2000ZS (Otsuka Electronics Co., Ltd.).

The results are shown in Table 1.

Examples 1-9 show that the use of a combination of the three different types of polyglyceryl fatty acid esters can provide transparent nano-emulsions including a variety of triglyceride oils.

Comparative Example 1 shows that a transparent nano-emulsion including a triglyceride oil cannot be provided when no first polyglyceryl fatty acid is used.

Comparative Example 2 shows that a transparent nano-emulsion including a triglyceride oil cannot be provided when no second polyglyceryl fatty acid is used.

Comparative Example 3 shows that a transparent nano-emulsion including a triglyceride oil cannot be provided when no third polyglyceryl fatty acid is used.

Claims

1. A composition comprising:

(a) at least one triglyceride oil;

(e) water,

wherein

the composition has a turbidity of 150 NTU or less, preferably 130 NTU or less and more preferably 110 NTU or less.

2. The composition according to Claim 1, wherein the (a) triglyceride oil comprises at least one plant oil.

3. The composition according to Claim 1 or 2, wherein the amount of the (a) triglyceride oil(s) in the composition ranges from 0.01 to 20% by weight, preferably from 0.05 to 15% by weight, and more preferably from 0.1 to 10% by weight, relative to the total weight of the composition.

4. The composition according to any one of Claims 1 to 3, wherein the fatty acid moiety of the

(b) first polyglyceryl fatty acid ester comprises 25 or more carbon atoms, preferably 30 or more carbon atoms, and more preferably 35 or more carbon atoms.

5. The composition according to any one of Claims 1 to 4, wherein the (b) first polyglyceryl fatty acid ester comprises 2 to 10 glycerol units, preferably 3 to 9 glycerol units, and more preferably 4 to 8 glycerol units. 6. The composition according to any one of Claims 1 to 5, wherein the weight ratio of the amount of the (b) first polyglyceiyl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition ranges from 0.

6 to 1.3, preferably from 0.7 to 1.2, and more preferably from 0.8 to 1.1.

7. The composition according to any one of Claims 1 to 6, wherein the fatty acid moiety of the

(c) second polyglyceiyl fatty acid ester comprises 8 to 18 carbon atoms, preferably 9 to 16 carbon atoms, and more preferably 10 to 14 carbon atoms.

8. The composition according to any one of Claims 1 to 7, wherein the (c) second polyglyceryl fatty acid ester comprises 2 to 10 glycerol units, preferably 3 to 8 glycerol units, and more preferably 4 to 6 glycerol units.

9. The composition according to any one of Claims 1 to 8, wherein the weight ratio of the amount of the (c) second polyglyceiyl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition ranges from 0.5 to 1.3, preferably from 0.6 to 1.2, and more preferably from 0.7 to 1.1.

10. The composition according to any one of Claims 1 to 9, wherein the fatty acid moiety of the

(d) third polyglyceryl fatty acid ester comprises 12 or less carbon atoms, preferably 11 or less carbon atoms, and more preferably 10 or less carbon atoms.

11. The composition according to any one of Claims 1 to 10, wherein the (d) third polyglyceiyl fatty acid ester comprises 2 to 10 glycerol units, preferably 3 to 8 glycerol units, and more preferably 4 to 6 glycerol units.

12. The composition according to any one of Claims 1 to 11 , wherein the weight ratio of the amount of the (d) third polyglyceryl fatty acid ester(s)/the amount of the (a) triglyceride oil(s) in the composition ranges from 0.1 to 1.1 , preferably from 0.2 to 1.0, and more preferably from 0.3 to 0.9.

13. The composition according to any one of Claims 1 to 12, wherein the weight ratio of

(the total amounts of the (b) first polyglyceryl fatty acid ester(s), the (c) second polyglyceryl fatty acid ester(s) and the (d) third polyglyceryl fatty acid ester(s))/the amount of the (a) triglyceride oil(s)

is 3.0 or less, preferably 2.5 or less, and more preferably 2.0 or less.

14. The composition according to any one of Claims 1 to 13, wherein the composition is in the form of an emulsion, preferably an O/W emulsion, and more preferably an O/W nano- or micro-emulsion.

15. The composition according to Claim 14, wherein the particle size of the (a) triglyceride oil is 35 nm or less, preferably 30 nm or less, and more preferably 25 nm or less.

16. A cosmetic process for treating a keratin substance, comprising the step of applying the composition according to any one of Claims 1 to 15 to the keratin substance.