WO2019235637A2

WO2019235637A2 - Syringe having movable syringe needle and camouflage pain point needle

Info

Publication number: WO2019235637A2
Application number: PCT/JP2019/022835
Authority: WO
Inventors: 義夫大山
Original assignee: 北川正人; 菅野博人; 森下裕道
Priority date: 2018-06-08
Filing date: 2019-06-08
Publication date: 2019-12-12
Also published as: JPWO2019235637A1; WO2019235637A3

Abstract

[Problem] To provide a syringe which has a user-friendly syringe needle, allays concerns pertaining to hygiene and danger before and after use, and allays anxiety from the invasiveness of the injection needle even during use. [Solution] A syringe comprising a syringe barrel 1, a needle-equipped gasket 2, and a plunger 4 to which a gasket 3 is mounted. In the injection cylinder 1, a container body 11 and a protective body 12 are integrally formed, and the protective body 12 is separated from a connection part 13 by being cleaved before use. An injection needle 22 is housed in the container body 11, and by operating the plunger 4 at the time of use, the injection needle 22 is exposed to the outside of the container body 11 and inoculates the skin. When doing so, two protruding parts 11_C1, 11_C2 at the tip of the container body 11 are brought into contact with the skin to press the epidermis and the dermis to such a degree that the epidermis and the dermis are not damaged, whereby another pain to the pain from the injection needle 22 is caused and the pain from the injection needle 22 is camouflaged and reduced. After use, the needle-equipped gasket 2 is returned to the inside of the container body 11 and the injection needle is housed therein.

Description

Syringe with movable injection needle and camouflaged pain point needle

The present invention relates to a syringe having an injection needle, and relates to one in which the injection needle moves and is exposed and pulled back, and one having a camouflaged pain point needle different from the injection needle.

Currently, there are various administration routes for pharmaceuticals in medicine, and representative examples of widely used ones include the oral route and the injection route.

The oral route is most commonly used for daily drug administration. If there is no mistake in the selection and dispensing of the medicine and the timing of ingestion is not wrong, there will be few major mistakes, and it can be said that it is a convenient, simple and safe administration method compared to the injection route. Therefore, in the home treatment, the current situation is to entrust oral administration of pharmaceuticals to individual patients. Examples of dosage forms used include tablets, capsules, and powders.

However, when administered orally, the drug is absorbed by the digestive organs such as the stomach and small intestine, so this drug may cause gastrointestinal damage or the drug may be degraded by gastric acid in the digestive tract (especially the stomach). . In addition, there is a problem that it takes some time until the effect is exhibited after absorption, and the effect is unstable. Furthermore, there is a problem that the absorption of the drug differs depending on the state of the digestive tract.

On the other hand, it can be said that the injection route is particularly effective in the case of a medicine that is not decomposed in the digestive tract or the like or is not absorbed in the digestive tract or the like. Specifically, there are several routes of administration such as intravenous, intramuscular, subcutaneous, and intradermal. By appropriately selecting these routes, the pharmacokinetics of the drug can be controlled.

That is, by injecting a drug directly into the body using an injection needle, the effect is quickly and stably manifested. The injection route allows the drug to be administered directly to the necessary site (affected area), so the time until the start of the effect is shorter than other administration methods, and it is filtered during the absorption process. It can be said to be a more reliable method because it can be administered even if it is denatured or decomposed by detoxification during the absorption process.

Thus, the administration method by the injection route is superior to the oral route. Due to its effectiveness, self-injection is permitted even in countries where injection is limited to medical practice by doctors (such as Japan). Examples of use include insulin injection for diabetes treatment, heparin injection for infertility prevention, blood coagulation factor drug self-injection for hemophilia treatment, and the like.

JP

However, it cannot be said that injection is sufficiently spread and utilized. The following problems 1 to 5 are inherent there.
1. Dangers in handling needles (eg needle stick accidents)
2. Dangers hidden in the use of drugs (incorrect selection and introduction of drugs)
3. Hygiene management of syringes (storage accidents and reuse)
4). Danger hidden in injection (depth of injection)
5). Pain when using a syringe (good / bad injection, drug irritation)

A needleless syringe without a needle has been considered as a solution to some of the above problems, but it is expensive, the impact sound is too loud when discharging a chemical solution, and secondary infection caused by reusing an expensive injector It is not popular for reasons such as.

On the other hand, syringes with needles are the most widespread, and the basic structure has not changed over the years. It can be said that it is simple and inexpensive. On the other hand, since a hollow needle is penetrated into a living tissue, a sense of refusal to the invasion and substantial damage are still a problem. In addition, existing syringes still have a problem that they cannot cope with complete virginity and countermeasures against infectious diseases.

The present invention has been made in view of the above points, and its purpose is to eliminate the dangers of hygiene and precautions before and after use because of excellent handling of the injection needle, and to prevent the invasion by the injection needle even during use. An object of the present invention is to provide a syringe capable of wiping off.

In order to solve the above problems, the present invention provides the following.

(1) It has a hollow cylindrical container body and a protective body that closes one end side of the container body and is connected to the inside and outside of the container body, and the protective body is an injection arranged in the container body. A syringe having a needle hole for protecting the needle.

According to the present invention, the syringe has a protective body that closes one end side of the container body, is formed continuously with the inside and outside of the container body, and has a needle hole portion that protects the injection needle. The injection needle is accommodated and protected in the needle hole portion in the body. Since the injection needle is housed in the container body by the protective body and one end side is closed, the injection needle is not exposed to the open air until it is actually used, and the hygiene of storing the syringe and the injection needle Excellent management.

The protective body can be formed integrally with the container body so that it can be easily separated, or can be mounted separately from the container body (for example, a cap). The needle hole is formed in the container body so that the syringe needle is accommodated in the container body and the injection needle is not exposed outside the container body even if separated from the protective body.

(2) A syringe characterized in that a protrusion projecting from the tip surface is formed at the tip of one end of the container body.

According to the present invention, when inoculating the tip surface in contact with the skin, the protruding portion presses the skin and can give a pain different from the pain of needle stick, making it difficult to feel the original pain of injection. be able to. This protrusion functions as a so-called camouflaged pain point needle, and disguises pain such that another needle is inserted around the needle. As a result, it is possible to solve the problem of the occurrence of pain during use, such as the skill of requiring injection with less pain (skilled skill) and the poor pain that causes extra pain.

(3) The syringe, wherein the bottom surface of the needle hole is positioned above the tip surface of the container body.

According to the present invention, since the bottom surface of the needle hole portion is located above the distal end surface of the container main body, the state in which the injection needle is accommodated in the container main body can be maintained before use. There is no concern of damaging the skin and the skin before, and the danger of lurking in handling the injection needle can be avoided.

(4) The protector includes a tip portion protruding from a tip surface of the container main body, and a gasket receiving portion in which the needle hole portion is formed, and the tip portion, the gasket receiving portion, and the container main body. A connecting part for connecting the container body, the connecting part is broken by applying a force to the tip part, and the container body and the protective body can be separated. Syringe.

According to the present invention, a force is applied to the tip portion by rotating or folding around the central axis, whereby the connecting portion is broken, and the container body and the protective body (tip portion and gasket receiving portion) are separated by cleavage. Since it is possible, the injection needle can be kept sealed until it is used, contamination of the syringe and the injection needle can be avoided, and the hygiene management is excellent. In addition, by using the cleavage property of the material to be used, the cross section can be formed into a flat cross section without unevenness. Thereby, even if it strongly presses a connection part (cut surface) to skin, safety | security can be ensured, without damaging skin by a cut surface.

(5) A syringe having a syringe needle that is positioned and fixed at the gasket receiving portion and is in contact with the inner peripheral surface of the container body.

According to the present invention, since the gasket with the needle is disposed in the gasket receiving portion, the gasket with the needle supported by the gasket receiving portion is in a state of being accommodated in the container body. Even after the protective part (gasket receiving part) is removed by removing the cap or cleaving, the needle-attached gasket is still in contact with the inner peripheral surface of the container body, so that the injection needle is still housed in the container body. Therefore, there is no fear of damaging the skin and the skin before use, and the danger of lurking in the handling of the injection needle can be avoided. Furthermore, since the injection needle is housed in the container body, the patient does not see the injection needle before and after use and during use, thus reducing mental stress such as giving fear to the patient. Can do.

(6) The syringe with the needle gasket having an introduction path for guiding the chemical solution to the injection needle and having a partition wall in the introduction path as a contact surface with the chemical solution.

According to the present invention, the upstream side where the chemical liquid is filled in the introduction path and the downstream side where there is no chemical liquid by the gasket with the needle that has the introduction path and has a partition wall that becomes a contact surface with the chemical liquid in the introduction path The medicine solution can be prevented from easily flowing into the injection needle. The gasket with the needle moves immediately before the inoculation, but in order to prevent the unintentional release of the chemical solution from the injection needle before the inoculation with this movement, the chemical solution that has broken or penetrated the septum by applying a predetermined pressure Flows into the needle. In addition, when the viscosity of the chemical | medical solution to ingest is large and the pressure loss at the time of flowing out of an injection needle is large, this partition is unnecessary.

(7) The syringe, wherein the partition wall has a mechanism for cutting or breaking through the partition wall.

According to the present invention, the degree to which the chemical solution breaks or penetrates the partition wall can be controlled by the partition wall having the cut. The number of cuts, depth, shape, etc. may be set according to the properties of the chemical (viscosity, etc.). Also, the degree of penetration through fracture can be controlled by providing the partition wall with a mechanism through fracture.

(8) The syringe, wherein the container body has an inner wall portion that is located above the one end side and protrudes in the inner circumferential direction.

According to the present invention, since it has an inner wall portion that is located above the one end side of the container body and protrudes in the inner circumferential direction, the movable gasket with the needle cannot move below the inner wall portion. It serves as a stopper for the attached gasket. Thereby, by restricting the movable range of the gasket with the needle and appropriately designing the length of the injection needle, it is possible to prevent the injection needle from penetrating the skin excessively. That is, the injection needle can be penetrated to an appropriate depth for each of intradermal injection, subcutaneous injection, intramuscular injection, and the like, which can contribute to selection of a syringe according to an application site such as an injection location and depth.

(9) A syringe having a gasket at the tip which is in contact with the inner peripheral surface of the container body and having a plunger disposed on the other end side of the container body.

According to the present invention, the plunger is arranged on the other end side of the container main body, and the container main body keeps the closed state at both ends by the plunger and the protector to block contact with the outside air. Excellent in hygiene management of syringes. Further, even if the plunger is pulled back, only the gasket remains in the container body, so that it is impossible to re-inject the drug solution into the syringe, and the syringe can be prevented from being reused.

(10) The gasket and the plunger are connected by a connecting body, and the connecting body moves the gasket in accordance with the pressing operation of the plunger, and is detached from the gasket in accordance with the pulling-out operation of the plunger. A syringe characterized by that.

According to the present invention, the gasket and the plunger are connected by the connecting body, and the connecting body moves the gasket in accordance with the pressing operation of the plunger. Therefore, the plunger and the gasket are pressed through the connecting body. Move to the bottom of the container body. On the other hand, since the plunger is detached from the gasket as the plunger is pulled out, the plunger and the gasket are separated, and only the plunger is pulled out of the container body, and the gasket stays in the container body. Thereby, since it becomes impossible to refill a chemical | medical solution in a container main body again, the reuse of a syringe and an injection needle can be prevented, and it is excellent on hygiene management.

(11) The syringe, wherein the plunger has a spring body that is restored in a direction opposite to the pressing direction.
(12) A syringe having a spring body that is restored between the gasket with the needle and the inner wall portion in a direction opposite to the pressing direction of the gasket with the needle.

According to the present invention, since the plunger or the gasket with the needle pressed by the restoring action of the spring body is pulled back, the gasket with the needle is also sucked with the movement of the plunger or directly and pulled back into the container body. Will be. At this time, since the injection needle is similarly pulled back into the container body, the skin and the skin are not damaged by the used injection needle, and the danger hidden in the handling of the injection needle can be avoided.

(13) A syringe in which the container body is filled with a chemical solution.

According to the present invention, it is possible to avoid problems such as a selection mistake of a medicine to be injected and a mistake in inoculation amount by filling the container body with a necessary chemical solution (completely virgin type prefilled). Furthermore, it is preferable to clarify the indication of which medicine is filled in which amount. In addition, when the plunger is pulled out, the gasket can be removed from the gasket, making it impossible to replace the already filled chemical without permission, preventing accidents and mistakes at the medical site, and reusing the syringe and needle. It can also contribute to prevention.

(14) A syringe characterized in that a storage portion for storing an anesthetic is provided at the rear end of the plunger.

According to the present invention, since the storage portion for storing the anesthetic is provided at the rear end of the plunger, the anesthetic can be applied to or attached to the skin before inoculation, so that pain during inoculation can be alleviated.

The syringe of the present invention avoids and solves the problems inherent in conventional syringes (the danger of lurking in the handling of injection needles, the mistake of drugs introduced into the syringe, and the occurrence of pain during use), and the application site for hygiene management There is an effect that an excellent syringe can be provided.

It is an exploded view of the syringe which concerns on embodiment of this invention. It is an assembly drawing of the syringe which concerns on embodiment of this invention. It is the schematic which shows the other example of the gasket with a needle | hook. It is a figure for demonstrating the effect | action of a projection part. It is an assembly drawing of the syringe using the plunger with a spring body. It is an exploded view of another syringe which concerns on embodiment of this invention. It is an assembly drawing of another syringe which concerns on embodiment of this invention. It is an exploded view of another syringe which concerns on embodiment of this invention. It is an assembly drawing of another syringe which concerns on embodiment of this invention. It is an exploded view of another syringe which concerns on embodiment of this invention. It is an assembly drawing of another syringe which concerns on embodiment of this invention. It is a figure for demonstrating the accommodating part which accommodates an anesthetic. It is a figure for demonstrating the usage method of a syringe. It is a figure for demonstrating the usage method of a syringe. It is a figure for demonstrating the usage method of a syringe.

Hereinafter, embodiments of the present invention will be described with reference to the drawings.

(Basic configuration of first syringe and syringe)
1A is an exploded view of the syringe according to the embodiment of the present invention, FIG. 1B is a view of the plunger 4 as viewed from above, and FIG. 2 is according to the embodiment of the present invention. It is an assembly drawing of a syringe. 1 and 2, the syringe is composed of a syringe barrel 1, a needle-attached gasket 2, and a plunger 4 to which a gasket 3 is attached.

The syringe barrel 1 is integrally formed with a hollow cylindrical container body 11 and a protective body 12 that closes the lower end side (one end side) of the container body 11. The container main body 11 has a ring-shaped upper handle 11a on the upper end side, a ring-shaped lower handle 11b on the slightly upper side, and two

protrusions

11 _C1 and 11 _C2 on the lower end (one end). And a ring-shaped inner wall portion 11 d that protrudes in the center direction from the inner wall surface of the container main body 11. Note that the number of protrusions is not limited to two. One or more may be sufficient. Further, the shape is not particularly limited, such as a cylinder, a prism, a cone or a pyramid. When pressed strongly against the epidermis, the surface should be sharp (dull) to the extent that it does not damage and feel a pressure and mild pain.

Further, the protector 12 integrally formed with the container main body 11 is formed with a knob portion 12a, a gasket receiving portion 12b, and a needle hole portion 12c formed in the gasket receiving portion 12b. Furthermore, a ring-shaped connecting portion 13 that connects the container body 11 and the protective body 12 is formed. When the protection body 12 is a cap type, the lower end (one end) of the container body 11 functions as the connection portion 13, and the connection by the connection portion 13 is released by rotating the cap, so that the container body 11 and the protection body 12 are released. And can be separated.

Further, the container body 11 and the protection body 12 can be separated by applying a force such as twisting or folding to the knob part 12a, and the connecting part 13 is broken. When the container main body 11 and the protective body 12 are integrally formed, the lower end surface 11e of the container main body 11 and the upper end surface 12d of the knob portion 12a of the protective body 12 are formed in different directions, so that the connecting portion 13 By forming a thin film, it is possible to reduce the force required for cleavage, and to reduce the cleavage plane (connecting portion 13) generated by cleavage.

Further, by using a material having cleaving properties, the separated cleaved surface (connecting portion 13) surface has no unevenness, and when the tip of the syringe 1 is pressed against the skin before taking out the injection needle, the connecting portion The risk of damaging the skin is eliminated by the 13 separate surfaces. Therefore, when the syringe 1 is pressed vertically against the skin, the broken and separated connecting portion 13 can be pressed firmly against the skin, and the cross section can be kept in contact with the skin surface. The depth of insertion can be defined to be constant. That is, the depth at which the injection needle 22 is inserted, such as subcutaneous injection or intramuscular injection, can be defined to a desired depth. On the other hand, the depth at which the injection needle 22 is inserted is not constant on the cut surface having the connecting portion 13 with severe irregularities, and ideal injection is impossible on the cut surface that damages the epidermis.

The cleaving material is composed of a known resin composition having a number average molecular weight of 1 × 10 ³ to 1 × 10 ⁶ obtained by polymerizing hydrogen, methyl, fluorine or the like. A material having high crystallinity is likely to cause broken pieces, and a material having excellent malleability and ductility such as PET has a problem that burrs and swells are likely to occur without being damaged, whereas a resin composition has an appropriate hardness. Clean breakage can be expected, and breakage can be prevented from occurring.

The needle-equipped gasket 2 has a gasket 21 and an injection needle 22. In the gasket 21, a hollow cylindrical upper ring portion 21a, a coaxial hollow cylindrical middle ring portion 21b, and a coaxial hollow cylindrical lower ring portion 21c are integrally formed.

The outer ring diameter of the upper ring portion 21a is substantially the same as the inner wall diameter of the container body 11, and prevents the chemical solution 5 filled in the container body 11 from flowing downward. The hollow portion of the upper ring portion 21 a is formed with an introduction path 21 d for guiding the drug solution 5 to the injection needle 22. This introduction path 21d has a shape in which the tip tapers as it goes downstream. The hollow portions of the middle ring portion 21b and the lower ring portion 21c are formed with an injection needle hole 21e for inserting and fixing the injection needle 22, and the injection needle 22 is inserted into the injection needle hole 21e. The introduction path 21d and the injection needle hole 21e communicate with each other and are integrally formed.

The outer diameter of the lower ring 21c is substantially the same as the inner wall diameter of the container body 11 and, together with the upper ring portion 21a, prevents the chemical solution 5 filled in the container body 11 from flowing out downward. Yes. Further, the outer peripheral diameter of the middle ring portion 21b is smaller than that of the upper ring portion 21a and the lower ring portion 21c and smaller than the inner wall diameter of the container body 11, thereby reducing the sliding friction caused by the movement of the needle-attached gasket 2. Yes.

The gasket 3 includes a hollow cylindrical upper ring portion 31a, a coaxial hollow cylindrical middle ring portion 31b, and a coaxial hollow cylindrical lower ring portion 31c that are integrally formed. The upper ring portion 31 a has an outer diameter that is substantially the same as the inner wall diameter of the container body 11, and the medicine liquid 5 filled in the container body 11 flows upward or downwards when the syringe is turned upside down. Is prevented. Further, the outer diameter of the lower ring 31c is substantially the same as the inner wall diameter of the container body 11, and together with the upper ring portion 31a, the drug solution 5 filled in the container body 11 is flowed upward or injected. The chemical solution 5 is prevented from flowing downward when it is turned upside down. The outer ring diameter of the middle ring portion 31b is smaller than that of the upper ring portion 31a and the lower ring portion 31c, and smaller than the inner wall diameter of the container body 11, thereby reducing the sliding friction caused by the movement of the gasket 3.

The upper ring portion 31a and the middle ring portion 31b of the gasket 3 are integrally formed with communicating

hollow portions

31d and 31e, the hollow portion 31d having a small diameter and the hollow portion 31e having a large diameter region. That is, the connecting body 41c inserted into the hollow portion can be moved with play in the large diameter region, and the gasket 3 can be moved downward as the plunger 4 is pressed.

On the other hand, since the connecting body 41c is detached from the gasket 3 as the plunger 4 is pulled out, the plunger 4 and the gasket 3 are separated. The detachment of the plunger 4 and the gasket 3 can be facilitated by an air hole 43 provided in the plunger 4, and the action of the air hole 43 requires a large force for the pull-out operation of the plunger 4, so that the connection body 41 c is connected. Is released. Such a basic operation is the same in the syringe shown in FIG.

The plunger 4 includes a disc-shaped handle portion 41a and a cylindrical or columnar plunger main body portion 41b which are integrally formed, and a connecting body 41c having a T-shaped cross section at the lower end of the plunger main body portion 41b. Is connected. The connecting body 41c is inserted into the upper ring portion 31a and the middle ring portion 31b of the gasket 3.

Here, the gasket 3 and the plunger 4 are weakly fitted or not fitted, and the plunger 4 is easily separated from the gasket 3 so that the gasket 3 left in the container body 11 is movable. I can't do it. This prevents the chemical solution from being refilled between the gasket 2 with a needle and the gasket 3. Alternatively, the connection body 41c that connects the gasket 3 and the plunger 4 is easily separated from the gasket 3 so that the gasket 3 left in the container body 11 cannot be moved.

As described above, the syringe including the syringe barrel 1, the needled gasket 2, and the plunger 4 to which the gasket 3 is attached is used after being assembled and manufactured as follows.
(1) The gasket 2 with a needle is inserted into the container body 11 of the syringe barrel 1 from the upper end of the opening and is brought into contact with the gasket receiving portion 12b. At this time, the injection needle 22 is accommodated in the needle hole portion 12c.
(2) The plunger 4 to which the gasket 3 is attached is attached in a state where the specified amount of the chemical solution 5 is filled in the container body 11 of the syringe barrel 1.
(3) At the time of use, by applying a force to the knob portion 12a, the connecting portion 13 is damaged and the container body 11 and the protective body 12 are separated. Thereby, the injection needle 22 comes into contact with the outside air for the first time.
(4) By performing an operation of depressing the plunger 4 so as to reduce the relative distance between the handle portion 41a and the upper handle portion 11a, the needle-attached gasket 2 is caused by the load pressure of the chemical solution 5 accompanying the movement of the gasket 3. The needle 22 is pushed out, and the injection needle 22 is exposed from the syringe barrel 1 and inoculated into the patient. Note that the movable range of the needle-attached gasket 2 is restricted using the inner wall portion 11d as a stopper.
(5) After inoculation, it is confirmed that the injection needle 22 has been pulled out from the patient, and the plunger 4 is pulled out, so that the needle-attached gasket 2 is applied by the load pressure in the container body 11 as the gasket 3 moves. Is pushed up, and the injection needle 22 enters the syringe barrel 1.
(6) When the operation of further pulling out the plunger 4 is performed, the plunger 4 and the gasket 3 are separated by the action of the connecting body connecting the plunger 4 and the gasket 3, and the plunger 4 is outside the container body 11. Although it can be pulled out, the gasket 3 remains in the container body 11.

FIG. 3 is a schematic view showing another example of the gasket 2 'with a needle, (A) is a cross-sectional view, and (B) is a cross-sectional view along AA. For convenience of explanation, the illustration of the injection needle 22 is omitted. Also, the needle-attached gasket 2 'may be used in the second, third, and fourth syringes.

The gasket 2 'with a needle is integrally formed with a hollow cylindrical upper ring portion 21a, a coaxial hollow cylindrical middle ring portion 21b, and a coaxial hollow cylindrical lower ring portion 21c. The outer diameter of each ring part is the same as that of the gasket 2 with a needle. The introduction path 21d is formed in the middle of the upper ring portion 21a and the middle ring portion 21b, and the injection needle hole 21e is formed in the middle of the middle ring portion 21b and the lower ring portion 21c.

In the upper ring portion 21a, a U-shaped chemical stopper 23 is inserted in contact with the outer peripheral wall 23b, and the introduction path 21d is vertically divided by the upper surface disk 23a. The upper surface disk 23a is formed with a symmetric cut line 23c at the center of the circle, and controls the outflow of the chemical solution from the upstream to the downstream in the introduction path 21d. The upper surface disk 23a uses soft rubber as a raw material, and has a role of preventing the medicinal solution 5 from passing through the injection needle 22 until a certain amount of internal pressure is applied to the soft rubber film having a cut. This prevents a small amount of the drug solution 5 from being released before the needle tip of the injection needle 22 pierces the skin if the viscosity of the drug solution 5 to be included is low when the gasket 3 moves forward.

As shown in FIG. 4, human skin is composed of the epidermis, dermis, and subcutaneous tissue from the outside, and muscles and veins are located in the subcutaneous tissue and further back. The reason why pain is felt when the needle is inserted into the skin is said to be that the needle hits the pain points distributed on the skin surface, and it is said that 100 to 200 pain points are distributed per 1 cm ² . Therefore, by using a fine needle that avoids the pain point as much as possible, there is a syringe that uses such a fine needle to reduce the pain at the time of inoculation, but no matter how thin the pain point is If you touch it, you will feel pain, and if a “pain substance” such as potassium ion, serotonin, or acetylcholine comes out from the needle-pierced cell, it will reach the end of the sensory nerve and feel pain. Therefore, the use of local anesthesia is considered as a reliable means to relieve pain. For example, the pain of the injection needle can be alleviated by applying a patch containing a local anesthetic containing lidocaine or applying a cream or the like.

On the other hand, it is said that human beings cannot feel multiple pains at the same time, and if there is another pain during injection, it is said that the pain of injection can be cheated. Classic examples include pinching the thigh, pinching the inoculation site, or raising the nail on the inoculation site, and getting used to other pains can alleviate the pain during inoculation. . It is said that nerves that convey pain are thin nerves, and those that are sensitive to touch and pressure are transmitted by thick nerves. A thick nerve has a phenomenon of suppressing the function of a thin nerve. It is well known that rubbing or holding down makes pain much easier, and even if you get injured and hurt, if you apply gauze and wrap a bandage, you will actually experience pain easily. is there.

FIG. 4 is a diagram for explaining the operation of the protrusion. By pressing the two

protrusions

11 _C1 and 11 _C2 against the skin and pressing them so as not to attack the epidermis and dermis (FIG. 4B), the pain due to the

protrusions

11 _C1 and 11 _C2 is given to the skin. Yes. During inoculation with the injection needle 22, another pain is given by the

protrusions

11 _C1 and 11 _C2, thereby accustoming to another pain. Note that the number of protrusions is not limited to two, and can be increased depending on the degree of pain. Moreover, it is also possible to use the projection body having such a projection portion by attaching it to the flat lower end of the syringe.

In addition, by increasing the number of protrusions to form intermittent or continuous ring-shaped protrusions and pressing them to the extent that they do not attack the epidermis and dermis by contacting the skin, An ischemic state can be achieved. Thereby, the pain of an injection needle is hardly felt by the stimulation pressure to skin, and the pain at the time of inoculation can be reduced.

FIG. 5 is an assembly diagram of a syringe using the plunger 4 with the spring body, and the spring body 6 is arranged on the outer peripheral surface of the plunger main body 41b. FIG. 5A is a view showing a state before use, and the spring body 6 is extended. FIG. 5B is a diagram showing a state in use. In a state where the plunger 4 is pushed down to expose the injection needle 22 from the syringe barrel 1, the spring body 6 is contracted. FIG. 5C is a diagram showing a state after use, and the spring body 6 is restored and is about to extend. The spring body 6 is an elastic member that generates a restoring force that is opposite to the pressing direction, and is formed of a metal such as aluminum or stainless steel or a resin. The syringe 3 having such a spring body 6 automatically moves the gasket 3 by the restoring force without performing the operation of pulling up the plunger 4, and the needle-attached gasket 2 is sucked by the accompanying load pressure in the container body 11. The injection needle 22 enters the syringe barrel 1 as it is pushed up.

In the second, third, and fourth syringes, the basic operation using the spring body 6 is the same as that shown in FIG. 5 regardless of the arrangement of the spring body 6.

(Second syringe)
FIG. 6 is an exploded view of another syringe according to the embodiment of the present invention, and FIG. 7 is an assembly view of another syringe according to the embodiment of the present invention. The syringe shown in FIG. 5 is similar to the syringe 1, the gasket 2 with the needle, and the plunger 4 to which the gasket 3 is attached. In addition, although the shape of the gasket receiving part 12b of the protection body 12 of the injection cylinder 1 is different, it is because of convenience when the spring body 6 is disposed on the outer peripheral surface of the plunger receiving part 12b.

According to this syringe, since the spring body 6 is arranged at the lower part of the needle-attached gasket 2, a restoring force is generated in the spring body 6 as the needle-attached gasket 2 is pushed down at the time of inoculation, and the plunger 4 is Without performing the operation of pulling up, the gasket 2 is pushed up by the restoring force of the spring body 6 after inoculation, and the injection needle 22 enters the syringe barrel 1.

(Third syringe)
FIG. 8 is an exploded view of another syringe according to the embodiment of the present invention, and FIG. 9 is an assembly view of another syringe according to the embodiment of the present invention. The basic configuration of the needle-attached gasket 2 is the same as that of the syringe of FIG.

5 Unlike the syringe of FIG. 5, the container body 11 of the syringe barrel 1 does not have a ring-shaped upper and lower handle. The plunger 7 to which the gasket 3 is attached includes an outer wall portion 71a, a plunger main body portion 71b that is linked with the outer wall portion 71a and spaced apart by a predetermined gap, and a lower end of the plunger main body portion 71b. A connecting body 71c having a T-shaped cross section is connected. The spring body 6 is disposed in a gap formed between the plunger main body 71b and the outer wall 71a. The upper end of the spring body 6 is on the upper surface of the outer wall 71a, and the lower end of the spring body 6 is on the opening of the container main body 11. Located on the end face.

According to this syringe, the gasket 3 is automatically moved by the restoring force of the spring body 6 without performing the operation of pulling up the plunger 7, and the gasket 2 with a needle is pushed up by the accompanying load pressure in the container body 11. Then, the injection needle 22 enters the syringe barrel 1.

(Fourth syringe)
FIG. 10 is an exploded view of another syringe according to the embodiment of the present invention, and FIG. 11 is an assembly view of another syringe according to the embodiment of the present invention. The syringe with needle 2 is the same as the syringe of FIG. 5, the configuration of the syringe barrel 1 is the same as the syringe of FIGS. 6 and 7, and the configuration of the plunger 7 is the same as the syringe of FIGS. Is the same.

(Anesthetic storage part)
FIG. 12 is a view for explaining the

storage portions

42 and 72 for storing the anesthetic 8, and is an upper portion of the handle portion 41 a located at the rear end of the plunger 4 or an outer wall portion located at the rear end of the plunger 7. Box-shaped

storage portions

42 and 72 are provided on the upper portion of 71a. The anesthetic 8 is sealed in a sealed container. When the anesthetic 8 is used, the container is taken out from the

storage portions

42 and 72 and applied to the skin for surface anesthesia. The anesthetic 8 may be a patch type or a cream type, and is taken out from the

storage portions

42 and 72 and applied or applied. Even if the

storage portions

42 and 72 are not provided separately, the rear end surfaces of the

plungers

4 and 7 are adhered to the storage portions 42 72 may function.

(How to use a syringe)
A method of using the syringe will be described with reference to FIGS.
(A) FIGS. 13A and 14A show a state before use.
(B) FIGS. 13A and 14A show a state where the protective body 12 is removed.
From (A) to (B), a storage portion 42 for storing the anesthetic 8 is provided at the tip of the handle portion of the plunger 4, and a hole is made in the storage portion 42 immediately before use of the syringe. Apply anesthetic 8 to the affected area. FIG. 15 (A) shows such a state. By giving anesthesia to the free nerve endings present in the epidermis and dermis, surface anesthesia is applied and needle pain can be reduced.

(C) FIGS. 13C and 14C show a state in which the plunger 4 is pushed in and the injection needle 22 is exposed.
From (B) to (C), the surface of the container body 11 is brought into contact with the skin after the surface anesthesia, so that the

protrusions

11 _C1 and 11 _C2 located at the tip are shallowly cut into the skin and the protrusion is stuck. Makes the brain feel. In addition, in the step of gradually piercing the needle in (C), the injection needle 22 is inserted into the skin while the illusion that the protrusion is stuck and hurts.

(D) FIG. 13 (D) and FIG. 14 (D) show a state in which the drug solution 5 is injected into the subcutaneous tissue.
FIG. 15 (B) shows this state, and the chemical solution 5 is applied to the subcutaneous tissue (about 2.3 mm below the skin surface) located below the epidermis (about 0.2 to 0.3 mm) and the dermis (about 2 mm). Inject.

(E) FIGS. 13 (E) and 14 (E) show a state in which all of the chemical liquid 5 has been injected.
The gasket 3 and the gasket with needle 2 are in contact with each other.

(F) FIGS. 13 (F) and 14 (F) show a state in which the plunger 4 is removed from the syringe barrel 1.
From (E) to (F), the needle-attached gasket 2 having the injection needle 22 is pulled back by the restoring force of the spring 6 and stored in the main body container 11.
If the plunger 4 is pulled strongly upward, the plunger 4 and the needle-attached gasket 3 are disconnected, and the needle-attached gasket 3 is left in the syringe barrel 1.
In the state (F), the syringe cannot be reused by re-injecting the drug solution between the gasket 4 and the needle-attached gasket 3.

The syringe according to the present invention is useful as anyone that can be safely and easily used by anyone.

DESCRIPTION OF SYMBOLS 1 Injection cylinder 2,2 'Needle gasket 3 Gasket (31a: Upper ring part 31b: Middle ring part 31c:

Lower ring part

31d, 31e: Hollow part)
4 Plunger (41a: handle portion 41b: plunger main body portion 41c: coupling body)
5 Chemical solution 6 Spring body 7 Plunger (71a: outer wall portion 71b: plunger main body portion 71c: connecting body)
8 Anesthetic agent 11 Container body (11a: upper handle part 11b: lower handle part 11 _C1 , 11 _C2 : protrusion 11d: inner wall part)
12 Protective body (12a: Knob part 12b: Gasket receiving part 12c: Needle hole part)
13 connection part 21 gasket (21a: upper ring part 21b: middle ring part 21c: lower ring part)
21d Introduction path 21e Injection needle hole 22 Injection needle 23 Chemical stopper (23a: Upper surface disk 23b: Outer wall)
42,72

Storage part

43,73 Air hole

Claims

A hollow cylindrical container body;
Closing one end side of the container body, and a protective body connected to the inside and outside of the container body;
Have
The syringe according to claim 1, wherein the protective body is formed with a needle hole portion that protects an injection needle disposed in the container body.
The syringe according to claim 1, wherein a protrusion projecting from the tip surface is formed at the tip of one end of the container body.
The syringe according to claim 1 or 2, wherein a bottom surface of the needle hole portion is located above a tip surface of the container body.
The protective body has a tip portion protruding from the tip surface of the container body, and a gasket receiving portion in which the needle hole portion is formed,
A syringe formed with a connecting portion for connecting the tip portion and the gasket receiving portion and the container body,
The syringe according to any one of claims 1 to 3, wherein when the force is applied to the distal end portion, the connecting portion is broken and the container body and the protective body are separable.
The syringe according to claim 4, wherein a gasket with a needle that has an injection needle that is positioned and fixed and is in contact with an inner peripheral surface of the container main body is disposed in the gasket receiving portion.
The gasket with a needle has an introduction path for guiding a chemical to the injection needle,
6. The syringe according to claim 5, further comprising a partition wall which becomes a contact surface with the drug solution in the introduction path.
The syringe according to claim 6, wherein the partition wall has a mechanism for cutting or breaking through the partition wall.
The syringe according to any one of claims 1 to 7, wherein the container body has an inner wall portion that is located above the one end side and protrudes in an inner circumferential direction.
The syringe according to any one of claims 1 to 8, further comprising a plunger disposed on the other end side of the container body, the gasket having a gasket abutting on the inner peripheral surface of the container body at the tip.
The gasket and the plunger are connected by a connecting body,
While the connecting body moves the gasket in accordance with the pressing operation of the plunger,
The syringe according to claim 9, wherein the syringe is detached from the gasket as the plunger is pulled out.
The syringe according to claim 9 or 10, wherein the plunger has a spring body that is restored in a direction opposite to the pressing direction.
The syringe according to any one of claims 6 to 8, further comprising a spring body that is restored between the gasket with the needle and the inner wall portion in a direction opposite to the pressing direction of the gasket with the needle.
The syringe according to any one of claims 1 to 12, wherein the container body is filled with a chemical solution.
The syringe according to any one of claims 9 to 13, wherein a storage portion for storing an anesthetic is provided at a rear end of the plunger.