WO2019220419A1 - Compositions pesticides synergiques et leur procédé de préparation - Google Patents

Compositions pesticides synergiques et leur procédé de préparation Download PDF

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Publication number
WO2019220419A1
WO2019220419A1 PCT/IB2019/054131 IB2019054131W WO2019220419A1 WO 2019220419 A1 WO2019220419 A1 WO 2019220419A1 IB 2019054131 W IB2019054131 W IB 2019054131W WO 2019220419 A1 WO2019220419 A1 WO 2019220419A1
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composition
fungicide
pesticidal composition
range
amount
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PCT/IB2019/054131
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English (en)
Inventor
Jayprakash Gopalkrishnan RAO
Avinash Vitthal BAGLE
Tanaji Shivaji BHAGAT
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Indofil Industries Limited
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Publication of WO2019220419A1 publication Critical patent/WO2019220419A1/fr

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • A01N47/14—Di-thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products

Definitions

  • the present disclosure relates to synergistic pesticidal compositions and a process for its preparation.
  • Crop protection using chemicals is a widely used method in agricultural pest management. These chemicals include pesticides such as insecticides, herbicides, fungicides, rodenticides, bactericides and larvicides. These pesticides commonly affect pests by either targeting the nerves, muscles, stomach, respiration, or growth of the organism.
  • pesticides such as insecticides, herbicides, fungicides, rodenticides, bactericides and larvicides. These pesticides commonly affect pests by either targeting the nerves, muscles, stomach, respiration, or growth of the organism.
  • a number of pesticides are used in combination for enhanced pesticidal effect. These mixtures of pesticides entail exposing an individual pest to each pesticide simultaneously, thereby enhancing the suppression of the pest population.
  • An advantage of mixing pesticides together is the reduction in the number of applications required, which in turn decreases the labor costs. It also reduces the incidence of pesticide resistance.
  • several insecticide and fungicide mixtures are also known to provide better pest control. However, such combinations do not provide sufficient and prolonged resistance from fungi and insects. Also, at times, the fungi and insects develop resistance to the pesticidal combinations.
  • Another object of the present disclosure is to provide a pesticidal composition having a synergistic effect.
  • Still another object of the present disclosure is to provide a pesticidal composition having an enhanced fungicidal and insecticidal activity and combats resistance shown by fungi and insects.
  • Yet another object of the present disclosure is to provide a synergistic pesticidal composition having high performance, in particular with regards to its efficacy against pests and the longevity of this efficacy so as to reduce the dosage applied to combat pest damage or attack of plants and crops.
  • Yet another object of the present disclosure is to provide a process for preparation of pesticidal composition.
  • the present disclosure relates to synergistic pesticidal compositions and a process for its preparation.
  • a synergistic pesticidal composition comprising a dithiocarbamate fungicide, a hen /imidazole fungicide, a neonicotinoid insecticide and agrochemically acceptable excipient.
  • the pesticidal composition shows synergistic effect and enhanced pesticidal activity as compared to the individual pesticides.
  • a process for preparation of a synergistic pesticidal composition comprises mixing a benzimidazole fungicide, a neonicotinoid insecticide, at least one dispersing agent, a wetting agent, an adjuvant and an antifreeze agent to obtain a first mixture.
  • the first mixture is diluted with water to obtain premix slurry.
  • the premix slurry is passed through a bead mill to obtain a concentrate suspension having a particle size in a predetermined range.
  • the concentrate suspension is mixed with a dithiocarbamate fungicide, a pigment, a defoamer, a thickening agent, a preservative and predetermined quantity of water to obtain the pesticidal composition.
  • Embodiments, of the present disclosure will now be described herein. Embodiments are provided so as to thoroughly and fully convey the scope of the present disclosure to the person skilled in the art. Numerous details are set forth, relating to specific components, and methods, to provide a complete understanding of embodiments of the present disclosure. It will be apparent to the person skilled in the art that the details provided in the embodiments should not be construed to limit the scope of the present disclosure. In some embodiments, well-known processes, well-known apparatus structures, and well-known techniques are not described in detail.
  • Pesticides when used alone or in combination, are prone to resistance from fungi and insects on prolonged and repeated exposure. Usage of individual pesticides also increases costs and dosages. Therefore, there is required a pesticidal composition that has a synergistic effect and thereby reduces need for multiple applications while providing better pesticidal activity.
  • the present disclosure provides synergistic pesticidal compositions and a process for its preparation.
  • a synergistic pesticidal composition comprising a dithiocarbamate fungicide, a benzimidazole fungicide, a neonicotinoid insecticide and agrochemically acceptable excipient.
  • the synergistic pesticidal composition comprises a dithiocarbamate fungicide in an amount in the range of 1% to 70% by weight of the total mass of the composition, a benzimidazole fungicide in an amount in the range of 1% to 60% by weight of the total mass of the composition, a neonicotinoid insecticide in an amount in the range of 1% to 60% by weight of the total mass of the composition and agrochemically acceptable excipient in an amount in the range of 0.1% to 65% by weight of the total mass of the composition.
  • the dithiocarbamate fungicide is selected from the group consisting of mancozeb, zineb, propineb, metiram, thiram, polycarbamate, ziram, dazomet, etem, milneb, mancopper, asamobam, asomate, azithiram, carbamorph, cufraneb, cuprobam, disulfiram, ferbam, metam, nabam, tecoram and urbacide.
  • the dithiocarbamate is selected from mancozeb, propineb and zineb.
  • Mancozeb is an ethylene bisdithiocarbamate (EBDC) fungicide, belonging to the group of dithiocarbamates, having a mode of action group M (Multi-site Action). It is a contact fungicide, acting on the surface of plants. Mancozeb reacts with, and inactivates, the sulfhydryl groups of amino acids and enzymes within fungal cells, resulting in disruption of lipid metabolism, respiration, and production of adenosine triphosphate. Mancozeb [CAS NO.
  • Propineb also known as Zinc l-methylethylenbisdithiocarbamate, is a fungicide used to combat fungal diseases such as powdery mildew, scab, etc. It also prevents spore germination. It possesses the following structure:
  • Zineb also known as zinc ethane- 1, 2-diylbis (dithiocarbamate), is polymeric complex. It is primarily used to control downy mildews, rusts, and redfire disease. It possesses the following structure:
  • the benzimidazole fungicide is selected from the group consisting of benomyl, carbendazim, furophanate, thiophanate, thiophanate-methyl, thiabendazole, fuberidazole, albendazole, chlorfenazole, cypendazole, debacarb, fuberidazole, mecarbinzid, rabenzazole and zoxamide.
  • the benzimidazole fungicide is selected from thiophanate-methyl and carbendazim.
  • Thiophanate-methyl is a systemic fungicide with protective and curative action. It is being absorbed by leaves and roots.
  • Thiophanate-methyl [CAS NO.23564-05-8] is a common name for Dimethyl 4, 4'-(o-phenylene) bis (3-thioallophanate) and possesses the following structure:
  • Carbendazim is also known as Methyl ///-benzimidazol-2-yl carbamate. It is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. The fungicide is used to control plant diseases in cereals and fruits, including citrus, bananas, strawberries, pineapples, and pomes. It possesses the following structure:
  • the neonicotinoid insecticide is selected from the group consisting of acetamiprid, clothianidin, dinotefuran, imidacloprid, imidaclothiz, nitenpyram, nithiazine, thiacloprid, cycloxaprid and thiomethoxam.
  • the neonicotinoid insecticide is selected from thiamethoxam and dinotefuran.
  • Thiamethoxam is a neonicotinoid compound with broad-spectrum insecticidal properties. It is a broad spectrum systemic insecticide having stomach & contact action. It is registered for use on numerous crops in many countries against sucking and chewing insects.
  • Thiamethoxam [CAS NO. 153719-23-4 ⁇ is a common name for 3-[(2-Chloro-l, 3-thiazol-5- yl) methyl ]-5-mcthyl-/V-nitro- 1 , 3, 5-oxadiazinan-4-imine and possesses the following structure:
  • Dinotefuran is an insecticide of the neonicotinoid class used for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers, sawflies, mole cricket, white grubs, lacebugs, billbugs, beetles, mealybugs, and cockroaches on leafy vegetables. Its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors. It is also known as 2-methyl-l-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine and possesses the following structure:
  • the agrochemically acceptable excipients are selected from the group consisting of dispersing agent, wetting agent, defoamer, emulsifiers, stabilizing agents, antifreeze agents, thickening agents, disintegrants, antifoaming agents, pigments, organic solvents, antioxidants, preservatives, adjuvants and filler.
  • the dispersing agent is selected from the group consisting of alkyl naphthalene sulfonate, bis (alkyl) naphthalene sulfonate formaldehyde condensates, naphthalenesulfonic acid formaldehyde condensates, phenol polyoxyethylene aryl sulfonate succinate , EO/PO block copolymers, polyoxyethylene octyl phenol ether sulfates, polycarboxylates, lignin sulfonates, alkaline earth metal and ammonium salts of aromatic sulfonic acids, such as lignin sulfonic acid polyoxyethylene alkyl phenol formaldehyde condensate ethyl sulfates, alkylbenzene calcium sulfonate, naphthalene sulfonate formaldehyde condensates sodium salts, polyoxyethylene alkylphenol ethyl
  • the wetting agent is selected from the group consisting of salts of aliphatic monoesters of sulphuric acid including sodium lauryl sulphate, sulfoakylamides and salts thereof , N - methyl - N - oleoyltaurate Na salt, akylarylsulfonates, akylbenzene sulfonates, akylnaphthalene sulfonates and salts thereof and salts of ligninsulfonic acid, aryl sulfonates (such as sodium dodecylbenzene sulfonate, sodium alkylnaphthalene sulfonate), fatty alcohol sulfates, alkyl sulfates, alkyl polyoxyethylene alcohol ether sulfate, polyoxyethylene alkyl phenol ether sulfate, polyoxyethylene alkyl phenol ether formaldehyde condensate sulfates, alkyl
  • the defoamer is selected from the group consisting of silicone oils, silicone-based compounds, compounds 00-20 unsaturated fatty acids and C8-10 aliphatic acids.
  • the stabilizing agent is selected from the group consisting of hexamethylenetetramine and sodium metabisulfite.
  • the antifreeze agent is selected from the group consisting of ethylene glycol, propylene glycol, glycerol, diethylene glycol, triethylene glycol and polyethylene glycol.
  • the thickening agent is a water-soluble polymer compound selected from the group consisting of xanthan gum, guar gum, or carboxymethyl cellulose, bentonite, PVOH, HMPC, Magnesium aluminium silicates and white carbon.
  • the disintegrant is selected from the group consisting of Ammonium sulfate, anhydrous sodium sulfate, calcium chloride, urea and potassium chloride.
  • the antifoaming agent is selected from the group consisting of silicone oils, silicon-based compounds, compounds of 00-20 unsaturated fatty acids and C8-10 aliphatic acids.
  • the preservative is selected from the group consisting of benzisothiazolinone (Proxel GXL) and Microcheck MZ 36.
  • the adjuvant is selected from the group consisting of fatty alcohol ethoxylate, polyether modified trisiloxane, trisiloxane ethoxylate, polyglycerol esters and fatty acid esters, sorbitan laurate, sorbitan monolaurate, polysorbate and modified polysiloxanes.
  • the filler is selected from the group consisting of clays, natural or synthetic silicates, kaolin, calcium carbonate, diatomaceous earth, bentonite, talc, clay, silica, resins, corn starch and attapulgite.
  • the organic solvents are selected from the group consisting of naphtha aromatic solvents, dimethyloctanamide, xylene and cyclohexanone.
  • the pigments are selected from the group consisting of pigment red, pigment blue, pigment orange, pigment violet, pigment green and pigment yellow.
  • composition will depend upon the type of composition and/or the manner in which the composition is to be applied by the end user.
  • the formulations can be of any form that is suitable for application onto all types of cultures or crops. These formulations, which can be prepared in any manner known by a person skilled in the art, also form part of this disclosure.
  • the synergistic pesticidal composition comprises a dithiocarbamate fungicide in an amount in the range of 1% to 70% by weight of the total mass of the composition, a benzimidazole fungicide in an amount in the range of 1% to 60% by weight of the total mass of the composition, a neonicotinoid insecticide in an amount in the range of 1% to 60% by weight of the total mass of the composition and agrochemically acceptable excipient selected from the group consisting of dispersing agent, wetting agent, defoamer, emulsifiers, stabilizing agents, antifreeze agents, thickening agents, disintegrants, antifoaming agents, pigments, organic solvents, antioxidants, preservatives, adjuvants and filler, in total, in an amount in the range of 0.1% to 65% by weight of the total mass of the composition.
  • the synergistic pesticidal composition comprises a dithiocarbamate fungicide in an amount in the range of 1% to 70% by weight of the total mass of the composition, a benzimidazole fungicide in an amount in the range of 1% to 60% by weight of the total mass of the composition, a neonicotinoid insecticide in an amount in the range of 1% to 60% by weight of the total mass of the composition and agrochemically acceptable excipient comprising at least one dispersing agent in an amount in the range of 1% to 15% by weight of the total mass of the composition, a wetting agent in an amount in the range of 0.1% to 5% by weight of the total mass of the composition, an adjuvant in an amount in the range of 0.1% to 10% by weight of the total mass of the composition, an antifreeze agent in an amount in the range of 0.1% to 10% by weight of the total mass of the composition, a defoamer in an amount in the range of 0.1 % to 2%
  • the synergistic pesticidal composition comprises Mancozeb in an amount in the range of 1% to 70% by weight of the total mass of the composition, Thiophanate-methyl in an amount in the range of 1% to 60% by weight of the total mass of the composition, Thiamethoxam in an amount in the range of 1% to 60% by weight of the total mass of the composition and agrochemically acceptable excipient in an amount in the range of 0.1% to 65% by weight of the total mass of the composition.
  • a lower dose of the synergistic pesticidal composition may offer adequate protection, whereas, certain climatic conditions, resistance offered by the pests, nature of the target phytopathogenic fungi or insect may necessitate higher doses of the synergistic pesticidal composition.
  • the synergistic pesticidal composition can be formulated in a dosage form selected from the group consisting of water dispersible granule, granules, dusts, oil-in-water emulsion, water-in-oil emulsion, oil dispersion, ZC formulation, wettable powder, suspension concentrate, flowable suspension, oil-based suspension and tank-mix.
  • a dosage form selected from the group consisting of water dispersible granule, granules, dusts, oil-in-water emulsion, water-in-oil emulsion, oil dispersion, ZC formulation, wettable powder, suspension concentrate, flowable suspension, oil-based suspension and tank-mix.
  • a process for preparing a synergistic pesticidal composition comprises mixing predetermined amounts of dithiocarbamate fungicide, benzimidazole fungicide, neonicotinoid insecticide and agrochemically acceptable excipient to obtain a pesticidal composition.
  • the process comprises mixing a benzimidazole fungicide, a neonicotinoid insecticide, at least one dispersing agent, a wetting agent, an adjuvant and an antifreeze agent to obtain a first mixture.
  • the first mixture is diluted with water to obtain premix slurry.
  • the premix slurry is passed through a bead mill to obtain a concentrate suspension of a particle size in a predetermined range.
  • the concentrate suspension is mixed with a dithiocarbamate fungicide, a pigment, a defoamer, a thickening agent, a preservative and predetermined quantity of water to obtain the pesticidal composition.
  • the pesticidal composition is formulated as a suspension formulation.
  • a process for preparation of the synergistic pesticidal composition comprises mixing predetermined quantities of benzimidazole fungicide, neonicotinoid insecticide, a wetting agent and a dispersing agent to obtain a first mixture.
  • the first mixture is milled to obtain a first homogenized mixture.
  • Predetermined quantities of a dispersing agent, an adjuvant, a pigment and a defoamer are mixed with water to obtain a second homogenized mixture.
  • the first homogenized mixture and the second homogenized mixture are mixed to obtain a third homogenized mixture.
  • a dithiocarbamate fungicide, a thickening agent and a preservative are added to the third homogenized mixture to obtain a pesticidal composition.
  • the pesticidal composition is formulated as a stable suspension.
  • a method of controlling and eliminating pests and fungal disease from plants comprising applying to pests, or locus of a pest, or plant or any plant propagation material, susceptible to attack by pests and fungi, an effective amount of the synergistic pesticidal composition.
  • the synergistic pesticidal composition is used against pests and fungi selected from the group consisting of Leaf spot ( Cercospora arachidicola ), Stem rot ( Sclerotium rolfsii), Aphids ( Aphis craccivora) and Thrips ( Scirtothrips dorsalis). Other fungi or insects or other infections and/or infestations caused by them can also be controlled with the synergistic pesticidal composition of the present disclosure.
  • the pesticidal composition surprisingly and unexpectedly allows a very high and perennial anti-fungal and anti-insecticidal efficacy against a broad spectrum of fungi and insects, particularly those responsible for diseases and/or damage of crops.
  • the pesticidal composition is used for foliar application, ground application or application to plants and/or propagation materials thereof.
  • the application is made to the soil before emergence of the plants, either pre-planting or post planting.
  • the applications are made by treatment of the propagation material, particularly seeds, with the synergistic pesticidal composition before planting.
  • the application is made as a foliar spray at different timings during crop development with one or more applications early or late post-emergence.
  • the synergistic fungicidal composition of the present disclosure is sold as a pre-mix composition or a kit of parts such that the individual actives can be mixed before spraying.
  • the constituents of the synergistic fungicidal composition can be tank-mixed and sprayed at the locus of the infection or alternatively be mixed with surfactants and then sprayed.
  • kits containing a pesticidal composition comprising a dithiocarbamate fungicide, a benzimidazole fungicide, a neonicotinoid insecticide and agrochemically acceptable excipient.
  • a pesticidal kit comprising a first sachet containing a first homogenized mixture comprising a benzimidazole fungicide, a neonicotinoid insecticide, a first dispersing agent, a second dispersing agent, a wetting agent, an adjuvant and an antifreeze agent, a second sachet containing a second homogenized mixture comprising a dithiocarbamate fungicide, a defoamer, a thickening agent, a preservative and a pigment and an instruction pamphlet, wherein the contents of the first sachet and the second sachet are to be combined, at the time of application, in accordance with the instructions provided in the instruction pamphlet.
  • the pesticidal composition of the present disclosure has enhanced pesticidal activity and combats resistance shown by the pests, fungi and insects.
  • the pesticidal activity of the pesticidal composition of the present disclosure is greater than the sum of the fungicidal activities of the individual components when used alone. Also, the difference in the modes of action of each of the active components translates into better management of fungi and insects. Hence, the pesticidal composition of the present disclosure can be applied in lower dosages. This in turn lowers the probability of development of resistance by the fungi and insects.
  • Example 1 Mancozeb 125g/l + TPM 125 g/l+Thiamethoxam 250g/l FS
  • Example 2 Mancozeb 125g/l + TPM 125 g/1 +Thiamethoxam 250g/l FS 220g of Thiamethoxam and l lOg of Thiophanate methyl with 20g of kraft lignin base lignosulphonate, lOg of sodium salt of naphthalene sulfonate condensate, 30g of graft co polymer, lOg of SLS, 30g of adjuvant and 80g of propylene glycol were mixed to obtain a mixture. The mixture was diluted with water to obtain a premix slurry in the form of a suspension. The premix slurry was passed through a bead mill to obtain a concentrate suspension of fine particle size in the range of 2 pm to 10 pm
  • Example 3 Mancozeb 125g/l + TPM 125 g/l+Thiamethoxam 250g/l FS
  • Example 4 Mancozeb 125g/l + TPM 125 g/l+Thiamethoxam 250g/l FS
  • Example 5 Mancozeb 125g/l + TPM 125 g/l+Thiamethoxam 250g/l FS
  • Example 6 Mancozeb lOQg/1 + TPM 110 g/l+Thiamethoxam 200g/l FS
  • Example 7 Mancozeb 140g/l + TPM 125 g/1 + Thiamethoxam 175g/l FS
  • Example 8 Zineb 15% + Carbendazim 10% + Thiamethoxam 25% - WP
  • Example 11 Mancozeb 50 % + Thiophanate-methyl 16 % + Thiamethoxam 6.25% WG
  • Example 12 Mancozeb 50 % + Carbendazim 16 % + Thiamethoxam 6.25% WG
  • Pesticidal formulations incorporated with different adjuvants were tested to determine the efficacy.
  • Example 1 was treated as the comparative formulation. Groundnut seed was selected for Germination study in the laboratory. For the laboratory study, dose of 5 pesticidal formulation (10ml /kg) was coated on groundnut seed and kept for 10 days on wet germination paper.
  • Adjuvant A Fatty alcohol ethoxylate
  • Adjuvant B Polyether Modified oxane
  • the formulation having Adjuvant A demonstrated faster root growth and better root length, no fungus growth compared to other examples and this formulation also showed greater efficacy when tested in field.
  • the synergistic pesticidal compositions of the present disclosure were tested at given concentrations with two way possible tank mix combinations, i.e., Mancozeb 75%WP + Thiamethoxam 25% WG (Tank mix), Mancozeb 75%WP + Thiophanate Methyl 70% WP (Tank mix) & Thiamethoxam 25% WG + Thiophanate Methyl 70% WP (Tank mix) along with solo individual fungicides i.e., Mancozeb 75% WP, Thiophanate Methyl 70% WP and Thiamethoxam 25% WG and Untreated Control against Leaf spot, Stem rot, aphids & thrips of Groundnut.
  • the appearance of the visible symptom of the diseases was recorded with observations after 10, 20, 30 & 40 days after seed treatment for recording the observations at ten plants from each plot were graded on (0-9) disease scoring scale for Leaf spot, Stem rot and number of pest count was recorded for Aphids, Thrips and growth (centimeters) and yield parameters (q/ha) of Groundnut.
  • PDI Percent disease index
  • the PDI values were transformed by angular transformation and analyzed statistically.
  • the disease control DC (%) was calculated by the following formula.
  • the three insecticide ready combinations were sprayed at doses X (100 ml/ 10 kg of seed) and 2X (200 ml/ 10 kg of seed) to check the phytotoxic effects like leaf injury on tips/surface, vein clearing, wilting, necrosis, hyponasty and epinasty on the Groundnut crop.
  • the observations on these phytotoxicity parameters were observed on before spray and at 1, 3, 5, 7, 10 and 15 days after application. But there was no any phytotoxicity observed on Groundnut crop after seed treatment in any treatment. Even there was no any adverse effect noticed on Groundnut crop in the field applied with this fungicides + Insecticide combinations at highest dose of @200 ml/ lOkg seeds.
  • test fungicide + Fungicides + Insecticide showed synergistic effect for controlling the diseases and insects. Also to prolong the effectiveness of fungicides liable to encounter resistance problems and to limit crop losses, the test fungicides can be used effectively and safely for the management of diseases as compared to solo Mancozeb 75 % wettable powder, Thiophanate Methyl 70% wettable powder and Thiamethoxam 25% water dispersible granules and their two way possible tank mix combinations.
  • the present disclosure described herein above has several technical advantages including, but not limited to, the realization of a synergistic pesticidal composition exhibiting enhanced efficacy for protecting plants, crops and seeds against fungal diseases and insect damages.
  • first, second, third, etc. should not be construed to limit the scope of the present disclosure as the aforementioned terms may be only used to distinguish one element, component, region, layer or section from another component, region, layer or section. Terms such as first, second, third etc., when used herein do not imply a specific sequence or order unless clearly suggested by the present disclosure.

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
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  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention concerne des compositions pesticides synergiques comprenant un fongicide dithiocarbamate, un fongicide de benzimidazole, un insecticide néonicotinoïde et au moins un excipient agrochimiquement acceptable. La présente invention concerne également un procédé de préparation d'une composition pesticide synergique. La composition pesticide synergique de la présente invention présente une efficacité améliorée pour protéger des plantes, des cultures et des graines contre des maladies fongiques et des dommages causés par des insectes.
PCT/IB2019/054131 2018-05-18 2019-05-20 Compositions pesticides synergiques et leur procédé de préparation WO2019220419A1 (fr)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007005470A2 (fr) * 2005-06-29 2007-01-11 Syngenta Participations Ag Compositions liquides destinees au traitement de matieres de propagation des vegetaux

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007005470A2 (fr) * 2005-06-29 2007-01-11 Syngenta Participations Ag Compositions liquides destinees au traitement de matieres de propagation des vegetaux

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