WO2019210469A1

WO2019210469A1 - Ventilation system and synchronous respiratory monitoring method and device

Info

Publication number: WO2019210469A1
Application number: PCT/CN2018/085388
Authority: WO
Inventors: 刘玲; 王慧华; 杨毅; 潘瑞玲; 潘纯; 刘京雷; 谢剑峰; 周小勇; 刘松桥; 邱海波
Original assignee: 东南大学附属中大医院; 深圳迈瑞生物医疗电子股份有限公司
Priority date: 2018-05-02
Filing date: 2018-05-02
Publication date: 2019-11-07
Also published as: CN110290824A

Abstract

A ventilation system and a synchronous respiratory monitoring method and device, comprising: an airflow supply device (1) for generating a ventilating airflow; a breathing conduit (2); a patient interface (3) which is in communication with the airflow supply device (1) by means of the breathing conduit (2) so as to deliver the ventilation airflow to the airway of a patient; a ventilation detection device (4) which is provided on the breathing conduit (2) or the patient interface (3) and is used for detecting ventilation parameters; a patient detection device (5) for detecting respiratory trigger information of the patient; a data processing device (6) used for acquiring the ventilation parameters and respiratory trigger information and calculating human-machine synchronization status information accordingly; and a human-machine interaction device (7), comprising a display device so as to display the human-machine synchronization status information outputted by the data processing device (6). The human-machine synchronization status information is used to express the degree to which human and machine are out of sync. By visually displaying the human-machine synchronization status information, medical staff may determine whether ventilation settings are reasonable, evaluate the condition of a patient, and then select appropriate intervention measures so as to reduce or eliminate human-machine antagonism and make the patient comfortable.

Description

Ventilation system and respiratory synchronous monitoring method and device

Technical field

The invention relates to a medical device, in particular to a ventilation system and a respiratory synchronization monitoring method and device.

Background technique

Under normal circumstances, the breathing process of the organism includes an inhalation phase of inhaling air or oxygen and an expiratory phase of exhaled air or carbon dioxide, and an adjacent inhalation phase and exhalation phase become a breathing cycle. In medical clinics, when an organism has a respiratory disorder, a ventilator is usually provided to provide respiratory support or assistance to the organism (eg, a patient or other patient).

When the patient does not have a spontaneous breathing effort, the ventilator assumes full responsibility for ventilating the patient. In this case, the ventilator establishes an inspiratory phase and an expiratory phase for the patient according to the inspiratory trigger point and the inspiratory end point set by the patient, and delivers air or oxygen to the patient by adjusting the airflow in the airway, and causes the patient to exhale air or carbon dioxide. . There is no human-machine confrontation in this case.

When the patient has a spontaneous breathing effort, the patient has its own inspiratory phase and expiratory phase. In this case, the inhalation phase and the expiratory phase of the ventilator are required to be synchronized with the patient's own inhalation phase and expiration phase. If it is not synchronized, there will be human-machine confrontation, which will cause discomfort to the patient.

In order to avoid human-machine confrontation, some ventilators designed a detection technology that the human-machine is not synchronized, compares the detected parameters with the set thresholds, determines whether there is respiratory unsynchronization, and outputs the judgment result to prompt the doctor to intervene. After the doctor sees an alarm message that the breathing is not synchronized or abnormal activity of the patient's discomfort, the usual practice is to inject the patient with a sedative, which may alleviate the patient's discomfort, but may delay the time of weaning.

Summary of the invention

The present application provides a ventilation system and a respiratory synchronization monitoring method and apparatus to visually display the degree of human-machine synchronization, and provide a reference for the formulation of a ventilation strategy.

According to a first aspect, an embodiment provides a ventilation system comprising:

a gas flow providing device for generating a ventilating gas stream;

Breathing line

a patient interface that communicates with the airflow providing device through the breathing circuit and is attached to the patient to deliver the ventilation airflow generated by the airflow providing device to the airway of the patient;

a ventilation detecting device disposed on the breathing circuit or the patient interface for detecting ventilation parameters;

a patient detecting device for detecting respiratory trigger information of the patient;

a data processing device, configured to acquire ventilation parameters and respiratory trigger information, and calculate human-machine synchronization state information according to the ventilation parameters and respiratory trigger information;

A human-machine interaction device includes a display for displaying human-machine synchronization status information output by the data processing device.

According to a second aspect, an embodiment provides a respiratory synchronization monitoring method, including:

Obtain ventilation parameters and respiratory trigger information;

Calculating man-machine synchronization state information according to ventilation parameters and breathing trigger information;

Outputs the HMI synchronization status information to the display for display.

According to a third aspect, an embodiment provides a respiratory synchronization monitoring apparatus, including:

Obtaining a module, configured to obtain ventilation parameters and respiratory trigger information;

a calculation module, configured to calculate human-machine synchronization state information according to ventilation parameters and respiratory trigger information;

An output module for outputting human-machine synchronization status information to the display for display.

According to a fourth aspect, an embodiment provides a computer readable storage medium comprising a program executable by a processor to implement the respiratory synchronization monitoring method described above.

According to the ventilation system and the respiratory synchronization monitoring method and apparatus of the above embodiment, the human-machine synchronization state information is calculated according to the obtained ventilation parameter of the airflow providing device and the patient's respiratory trigger information, and the human-machine synchronization state information is displayed. Therefore, it is possible to visually display the degree of unsynchronization of the human-machine, so that the doctor can select an appropriate intervention according to this.

DRAWINGS

1 is a schematic structural view of a ventilation system according to an embodiment of the present invention;

2 is a schematic structural view of a respiratory synchronization monitoring device according to an embodiment of the present invention;

3 is a flowchart of a respiratory synchronization monitoring method according to an embodiment of the present invention;

4 is a two-dimensional trend point diagram showing human-machine synchronization state information in an embodiment of the present invention;

FIG. 5 is an analysis diagram of a degree of synchronization of a human-machine corresponding to any coordinate point according to an embodiment of the present invention; FIG.

6 is a distribution diagram of displaying synchronization information of a human-machine in an embodiment of the present invention;

FIG. 7 is another distribution diagram of displaying human-machine synchronization state information according to an embodiment of the present invention; FIG.

FIG. 8 is a trend table diagram showing information about synchronization status of a human-machine in an embodiment of the present invention; FIG.

FIG. 9 is another trend chart showing the synchronization state information of the human-machine in the embodiment of the present invention; FIG.

FIG. 10 is a diagram showing a change trend of the degree of synchronization state of each type of human-machine in the embodiment of the present invention; FIG.

FIG. 11 is a comparison diagram of changes in the degree of synchronization of various types of human-machines according to an embodiment of the present invention; FIG.

FIG. 12 is a schematic diagram of selecting a time period in a two-dimensional trend point map according to an embodiment of the present invention; FIG.

13 is a data comparison analysis table of the degree of synchronization of human-machines in any two periods of time according to an embodiment of the present invention;

14 is a comparative pie chart of the degree of synchronization of human-machines in any two periods of time according to an embodiment of the present invention;

15 is a three-dimensional distribution diagram of a degree of synchronization of a human-machine corresponding to any two periods of time in an embodiment of the present invention;

FIG. 16 is a three-dimensional comparative distribution diagram of the degree of synchronization of human-machines in any two periods of time according to an embodiment of the present invention.

detailed description

The present invention will be further described in detail below with reference to the accompanying drawings.

In the embodiment of the present invention, the human-machine synchronization state information is calculated according to the obtained ventilation parameter of the ventilation system and the respiratory trigger information of the patient, and the human-machine synchronization state information is displayed, and the human-machine synchronization state information is used to represent the human-machine The degree of out of sync.

The embodiment of the present invention provides a ventilation system. Referring to FIG. 1 , FIG. 1 is a schematic structural diagram of a ventilation system according to an embodiment. As shown in FIG. 1 , the ventilation system includes an airflow providing device 1 and a breathing pipeline 2 . a patient interface 3, a ventilation detecting device 4, a patient detecting device 5, a data processing device 6, and a human-machine interaction device 7; wherein the airflow providing device 1 is in communication with the patient interface 3 via a breathing circuit 2, and the patient interface 3 may include a mask, a nasal mask, a nasal cannula, a tracheal tube, etc., attached to the patient, capable of delivering a ventilation airflow generated by the airflow providing device 1 to the airway of the patient; the ventilation detection device 4 is disposed on the respiratory conduit 2 or the patient interface 3, For detecting a ventilation parameter, for example, detecting at least one of a pressure, a flow rate, and a volume waveform of the ventilation airflow; the patient detection device 5 is configured to detect a respiratory trigger information of the patient, wherein the respiratory trigger information includes a respiratory mechanics parameter or a respiratory electrical parameter, For example, esophageal pressure, diaphragmatic muscle, etc., these parameters may be numerical values, waveforms, icons or other forms; the data processing device 6 is used to obtain the ventilation detecting device 4 The detected ventilation parameter and the respiratory trigger information detected by the patient detecting device 5, the human-machine synchronization state information is calculated according to the ventilation parameter and the breathing trigger information, and then the human-machine synchronization state information is output to the human-machine interaction device 7; the human-machine interaction device 7 The display device is configured to display the human-machine synchronization state information output by the data processing device 6, and the human-machine synchronization state information includes a degree of inhalation trigger difference and an inhalation end difference degree, and may further include a chart, a number, a color, a character, and the like. One or more for visually characterizing the degree of human-machine out of sync. In practical applications, the human-machine interaction device 7 further includes an input device through which the user can set various parameters and select and control the display interface of the display to realize information interaction between the human and the machine.

Specifically, the data processing device 6 can obtain the time of the patient's inhalation trigger and the time of the inhalation end according to the collected respiratory trigger information, and can also obtain the inspiratory triggering time of the respiratory system and the inhalation end time according to the collected ventilation parameters. . The human-machine interaction device 7 can display the human-machine synchronization state information through at least one of text, data, a table, a trend graph, a distribution map, and an analysis graph.

Based on the same inventive concept, the embodiment of the present invention further provides a respiratory synchronization monitoring device, which can be applied to a respiratory mechanics module, a ventilator, an anesthesia machine, and a ventilation monitoring instrument with a ventilation function monitor. 2 is a schematic structural diagram of a respiratory synchronization monitoring device. As shown in FIG. 2, the respiratory synchronization monitoring device includes an acquisition module 01, a calculation module 02, and an output module 03. The acquisition module 01 is configured to acquire a ventilation parameter and a respiratory trigger. Information, the ventilation parameter includes at least one of a pressure, a flow rate, and a volume waveform of the ventilation airflow, and the respiratory trigger information includes a respiratory mechanics parameter or a respiratory electrical parameter, such as an esophageal pressure, a diaphragmatic muscle, etc., and the parameters may be values, waveforms, icons, or The calculation module 02 is configured to calculate the human-machine synchronization state information according to the ventilation parameter and the respiratory trigger information acquired by the acquisition module 01, and the output module 03 is configured to output the human-machine synchronization state information calculated by the calculation module 02 to the display for display. . The human-machine synchronization state information includes a degree of inhalation trigger difference and an inhalation end difference degree, and may also include one or more of a chart, a number, a color, a character, etc., and the human-machine synchronization state information can visually represent the person. The degree of unsynchronization of the machine so that the medical staff can choose the appropriate intervention accordingly.

Specifically, the calculation module 02 is further configured to obtain, according to the collected respiratory trigger information, a time of the patient's inhalation trigger and a time of inhalation, and obtain a time of the inspiratory trigger of the respiratory system and a time of inhalation according to the collected ventilation parameter. . The output module 03 is configured to output the human-machine synchronization status information to the display, so that the display displays the human-machine synchronization status information through at least one of text, data, a table, a trend graph, a distribution map, and an analysis graph.

The respiratory synchronization monitoring device can be a separate module attached to various ventilation systems (eg, respiratory mechanics modules, ventilators, anesthesia machines, with ventilation function monitors), or integrated into the data processing device of the ventilation system, such as In the data processing device 6 shown in FIG.

Based on the ventilation system or the respiratory synchronization monitoring device, the embodiment of the present invention provides a respiratory synchronization monitoring method, and FIG. 3 shows a flowchart of the respiratory synchronization monitoring method. As shown in FIG. 3, the respiratory synchronization monitoring method may include The following steps:

Step S11: Acquire ventilation parameters and respiratory trigger information.

The data processing device 6 or the acquisition module 01 of the respiratory synchronization monitoring device acquires the ventilation parameter detected by the ventilation detecting device 4 and the respiratory trigger information of the patient detected by the patient detecting device 5, wherein the ventilation parameter includes the pressure, flow rate and volume of the ventilation airflow. At least one of the waveforms, the respiratory trigger information includes a respiratory mechanics parameter or a respiratory electrical parameter, such as esophageal pressure, diaphragmatic electromyography, etc., which may be a numerical value or a waveform.

Step S12: Calculate the human-machine synchronization state information.

The calculation module 02 of the data processing device 6 or the respiratory synchronization monitoring device calculates the human-machine synchronization state information according to the ventilation parameter and the respiratory trigger information, and the human-machine synchronization state information includes the inhalation trigger difference degree and the inhalation end difference degree, and may also include One or more of charts, numbers, colors, characters, etc., used to visually characterize the degree of human-machine out of sync.

The degree of difference between the inhalation trigger and the degree of end of the inhalation are used to characterize the degree of unsynchronization of the human-machine, and may be expressed by a time difference or by a ratio. Specifically, the difference of the inhalation trigger is the time difference of the inhalation trigger, and the difference of the end of the inhalation is the time difference of the inhalation end; or, the difference of the inspiratory trigger is the ratio of the time difference of the inhalation trigger to the duration of the inhalation phase of the patient, suction The difference in the end of the gas is the ratio of the time difference between the end of inspiration and the length of the patient's expiratory phase; or, the difference in the inspiratory trigger is the ratio of the time difference between the inspiratory trigger and the duration of the inspiratory phase of the ventilation system, and the difference in inspiratory end is the suction The ratio of the time difference between the end of the gas and the duration of the expiratory phase of the ventilation system; or the degree of difference in the inspiratory trigger is the ratio of the time difference between the inspiratory trigger and the average of one respiratory cycle or multiple respiratory cycles of the patient, and the degree of difference in inhalation end The ratio of the time difference between the end of inspiration and the average of one respiratory cycle or multiple respiratory cycles; or, the difference in inspiratory triggering is the time difference between the inspiratory trigger and the average of one respiratory cycle or multiple respiratory cycles of the ventilation system The ratio of values, the difference in end of inspiration is the time difference between the end of inspiration and one breath week of the ventilation system The ratio of the mean of the period or periods of breathing.

In the process of indicating the degree of difference between the inhalation trigger and the degree of inhalation end, it is necessary to calculate the time difference between the inspiratory trigger and the end of inspiration. The time difference of the inspiratory trigger refers to the inspiratory trigger time of the ventilation system and the patient inhalation trigger. The time difference between the times and the time difference between the end of inhalation refers to the time difference between the inhalation end time of the ventilation system and the end time of the patient inhalation. The acquisition of the time at which the patient inhales the trigger and the time at which the inhalation is triggered, and the timing of the inspiratory trigger of the ventilation system and the timing of the end of the inhalation may be acquired by the data processing device 6 or the calculation module 02 of the respiratory synchronization monitoring device. The breathing trigger information obtains the time at which the patient inhales the trigger and the time at which the inhalation ends, and the time of the inhalation trigger of the ventilation system and the time of the end of the inhalation are obtained according to the collected ventilation parameters.

Specifically, the data processing device 6 or the calculation module 02 of the respiratory synchronization monitoring device may first obtain a respiratory trigger information waveform that changes with time according to the collected respiratory trigger information, and then read the time of the patient's inhalation trigger according to the respiratory trigger information waveform. The time at which the inhalation ends; or, the time at which the patient inhales the trigger and the time at which the inhalation ends can be calculated directly based on the collected respiratory trigger information. Similarly, the waveform of the ventilation parameter that changes with time can be obtained according to the collected ventilation parameter, and then the time of the inhalation trigger of the ventilation system and the time of inhalation end are read according to the waveform of the ventilation parameter; or, according to the acquisition, The ventilation parameters calculate the time of the inspiratory trigger of the ventilation system and the moment of inspiration.

Step S13: Display man-machine synchronization state information.

The output module 03 of the human-machine interaction device 7 or the respiratory synchronization monitoring device outputs the human-machine synchronization state information to the display, so that the display displays the synchronization state of the human-machine through at least one of text, data, table, trend, distribution, and analysis. information.

The trend graph is a distribution of the degree of synchronization of the human-machine synchronization state in each predetermined time period along the time axis, and the distribution of the degree of the synchronization state of the human-machine includes the distribution position or the number of times, and the distribution position may be in the middle of the cell. In a manner, a method of changing a position with a value may also be adopted; the trend graph may include at least one of a two-dimensional trend point map, a trend table graph, and a change trend comparison graph. The distribution map is a three-dimensional map between the degree of inspiratory trigger difference, the degree of end of inspiration, and time over any period of time. The analysis chart includes a human-machine synchronization state degree analysis map at a selected time and/or a difference comparison analysis diagram of the human-machine synchronization state for at least two periods of time.

Specifically, the two-dimensional trend point map is a two-dimensional map of the degree of difference in the degree of difference in inspiration triggering with time and the degree of difference in the degree of inhalation end as a function of time. FIG. 4 is a schematic diagram showing the synchronization state information of the human-machine in a two-dimensional trend point diagram. As shown in FIG. 4, the coordinate system is established by using the time as the horizontal axis and the degree of the suction trigger difference as the vertical axis, and each point in the figure represents A breathing cycle in which the change in position of the point in the graph over time represents a change in the degree of difference in inspiratory triggering over time during the predetermined period of time; likewise, the difference in time between the horizontal axis and the end of inspiration The degree is the vertical axis to establish a coordinate system. Each point in the figure represents a breathing cycle. During the predetermined time period, the change of the position of the point in the graph with time represents the change of the degree of inspiration at the end of the predetermined time period. . In practical applications, the two two-dimensional trend point maps in Figure 4 are generally displayed in pairs to facilitate observation, comparison, and analysis by the medical staff, in which the degree of difference between the inspiratory trigger and the degree of end of inspiration are expressed as a percentage. In the two figures, the range of tolerable differences can be displayed in the form of colors, boundaries, etc. For example, in Figure 4, the tolerable difference range is displayed in a shaded area, which can tolerate the difference range such as setting 30% of soil, if two at the same time If the points in the figure fall within the area, it means that the degree of difference between the inhalation trigger and the end of the inhalation at this moment can be tolerated. It can be considered that the degree of synchronization of the human-machine at that moment is in the state of synchronization between human and machine. The person does not need to implement any intervention measures; if the point in the figure falls outside the area, the degree of synchronization of the human-machine at that moment is considered to be in a state of unsynchronized man-machine, resulting in man-machine confrontation, and the position of the point deviates from the area. Farther, the more serious the unsynchronized man-machine, at this time, the medical staff can judge whether the ventilation setting is unreasonable according to the severity of the human-machine synchronization, or Whether the patient's condition changes, and then choose appropriate interventions to reduce or eliminate human-machine confrontation and make the patient comfortable.

In Fig. 4, a coordinate point represents a breathing cycle, and any coordinate point can be selected to display a human-machine synchronization state degree analysis map of the breathing cycle corresponding to the coordinate point, which includes the respiratory trigger information waveform and ventilation of the selected coordinate point. Parameter waveform; for example, selecting the A coordinate point in Fig. 4, the degree of synchronization of the human-machine synchronization state of the A coordinate point can be analyzed, and the analysis chart is displayed; FIG. 5 shows the esophageal pressure corresponding to the selected respiratory cycle (Pes The waveform of the waveform and the flow rate of the ventilating airflow, wherein the upper graph is a waveform diagram of the esophageal pressure (Pes) corresponding to the respiratory cycle, and is used to reflect the respiratory condition of the patient, and the lower graph corresponds to the respiratory cycle. The flow rate of the ventilating airflow is used to reflect the ventilation of the ventilation system; as shown in Fig. 5, in the waveform diagram of the esophageal pressure, the positions of the broken line a and the broken line b represent the time and suction of the patient's inhalation trigger, respectively. At the end of the gas, the positions where the dotted line a and the broken line b are located are respectively compared with the inhalation triggering timing a' of the ventilation system in the lower flow velocity waveform diagram and the inhalation ending timing b' of the ventilation system. Line comparison, by analyzing the difference to feedback whether the inspiratory and exhalation between the patient and the ventilation system are synchronized and the degree of their synchronization; the analysis of Fig. 5 shows that for the A coordinate point, the inspiratory triggering moment of the ventilation system and The inspiratory end time is delayed compared to the patient's inspiratory triggering time and inspiratory end time. The inhalation trigger difference is delayed by 20%, and the inspiratory end difference is delayed by 25%. The result can be digital, Text, forms, etc. are displayed directly on the display screen so that the medical staff can intuitively understand the degree of unsynchronized man-machine; the result is within 30% of the tolerable difference range set in Figure 4, at this time Although the machine is not synchronized, the degree of unsynchronization is within the allowable range. At this time, the medical staff can not implement the intervention. Optionally, the “previous record” and “next record” menus may also be set on the display interface of FIG. 5 to facilitate viewing of the history.

In practical applications, the cursor can also be selected from the waveform diagram shown in FIG. 4 for any period of time. For example, in FIG. 4, two vertical lines c and d respectively represent the selected start time and end time, and then display this. The period of time (2017/10/2017:12:00～2017/10/2017:20:00) corresponds to the degree of synchronization of the human-machine. Optionally, at the position where the cursor arrives, the inhalation trigger difference degree value and the inhalation end difference degree value corresponding to the position coordinate point may be displayed, as shown in FIG. 4, 28% and 10%.

Figure 4 shows the human-machine synchronization state information in the form of a two-dimensional trend point map. In actual application, it can also be displayed in the form of a distribution map, which is the degree of inhalation trigger difference and end of inspiration during any period of time. A three-dimensional map of the degree of difference and time. 6 is a distribution diagram showing the synchronization state information of the human-machine, which is described by using 30 minutes as a predetermined time period. As shown in FIG. 6, the distribution map has a degree of difference in the end of the inhalation as the horizontal axis and the inhalation trigger. The degree of difference is the coordinate system established by the vertical axis, and the degree of synchronization of the human-machine state is represented by the position of the point in the coordinate system. The map is divided into four regions according to the quadrant of the coordinate system, representing four different types of human-machine synchronization state levels, specifically: the first quadrant (upper right corner region) represents the inspiratory trigger and the inspiratory end delay, and the second The quadrant (upper left corner area) represents the inspiratory trigger delay and the inspiration ends too early, the third quadrant (lower left corner area) represents the inspiratory trigger and the inspiratory end is too early, and the fourth quadrant (lower right corner area) represents the inspiratory trigger Early and inhalation is delayed. At the same time, the distribution map is provided with a preset area indicating the synchronization state of the human-machine, as shown in the shaded area in FIG. 6, which can be set to the fifth type of synchronization state of the human-machine, which is called the human-machine synchronization state; 4 is the same, although the points falling within the area are also unsynchronized, but the degree of unsynchronization is within the allowable range, at this time, the medical staff may not implement the intervention. For example, for point A in Figure 6, it is located in the upper right corner area, and both the inspiratory trigger and the inspiratory end are delayed, but if it is within the set shaded area, the degree of unsynchronized man-machine is allowed, then it can be considered It is a state of synchronization between humans and machines, and no medical personnel are required to implement any interventions.

Fig. 6 is to establish a coordinate system with the degree of difference in the end of inspiration as the horizontal axis and the degree of difference in the inspiratory trigger as the vertical axis. In actual application, the degree of difference in the inspiratory trigger can be established as the horizontal axis and the difference in the end of inspiration is the vertical axis. The coordinate system is not limited here.

Optionally, a setting menu that can tolerate a range of differences can be set on the display interface of FIG. 4 or FIG. 6 , and the setting menu is used to set an allowable range of the degree of unsynchronized man-machine, that is, used to set FIG. 4 and The size of the shaded area in Fig. 6; for example, the "tolerable difference degree range" menu shown in Fig. 6, the specific percentage value can be set by the medical staff as needed, for example, set to 30%.

In practical applications, the figures shown in Figures 4-6 can be displayed separately on the display screen, or can be displayed in any combination. The display screen can also be displayed in text, data and/or characters in the preset display area. The total number of breathing cycles, the most recent measurement of the degree of unsynchronized man-machines, and the number of human-machine asynchronous events, so that medical personnel can more intuitively understand the degree of human-machine synchronization.

In the three-dimensional map shown in FIG. 6, when the distribution of points is dense, the number of points of each area may be represented by a color, thereby indicating the degree of synchronization of the human-machine state by the color area in the coordinate system. FIG. 7 shows another distribution diagram showing the synchronization state information of the human-machine. As shown in FIG. 7, the four quadrants and the preset regions indicating the synchronization state of the human-machine can be distinguished by different colors, and the figure is provided with A comparison table of the number of colors and the number of dots, different colors correspond to the number of different points; the area of the dotted circle in the figure is the distribution of points represented by colors, and the positions of the colors are compared and the number of points and colors are compared. The comparison table can be used to know the synchronization status information of the human-machine, thereby obtaining the degree of synchronization of the human-machine.

The man-machine synchronization state information can also be displayed in the form of a trend table diagram. By establishing a table in which the degree of human-machine synchronization state and time are corresponding, the degree of synchronization of the man-machine is qualitatively represented by a point or a number in each cell of the table. , or quantify the degree of human-machine synchronization status by the position of the point in the cell.

Specifically, FIG. 8 shows a trend table showing the synchronization status information of the human-machine. As shown in FIG. 8, the synchronization state information of the human-machine is reflected by the degree of synchronization of the human-machine, and the degree of synchronization of the human-machine includes the inhalation trigger. 5 types of premature end of inhalation, premature inspiration triggering, inhalation end delay, man-machine synchronization state, inhalation trigger delay and inhalation end prematurely, and inspiratory trigger and inspiratory end delay. Corresponding to the five types in Figure 6; the time resolution selects a single breathing cycle, here a single breathing cycle of 8s is taken as an example. In the table shown in FIG. 8, the row in which the man-machine synchronization state is located, the cell corresponding to each time, the horizontal direction indicates the degree of difference in inhalation end, the vertical direction indicates the degree of inspiration trigger difference, and the lower left corner indicates the coordinate value (-30, -30), the upper right corner indicates the coordinate value (30, 30). These two coordinate values define the allowable range of the degree of human-computer unsynchronization within 30%. The position of the drawn point in the cell can quantitatively indicate the degree of difference. Size; other lines except the human-machine synchronization state, the cells corresponding to each time, the horizontal direction indicates the degree of difference in inhalation end, the vertical direction indicates the degree of inspiration trigger difference, the lower left corner indicates the coordinate value (0, 0), and the upper right corner indicates The absolute value (100, 100), the position of the point in the cell, quantitatively indicates the degree of difference. Among them, the numerical unit of each cell is a percentage.

Alternatively, in the trend table shown in FIG. 8, the point in each cell may be in the center of the cell, thereby qualitatively showing the degree of synchronization of the human-machine.

Optionally, when qualitatively displaying the degree of synchronization of the human-machine, the points in the cell may be represented by numbers, for example, a place with a point is represented by 1, and a place without a point is represented by 0. FIG. 9 is a diagram showing another trend table for displaying the synchronization state information of the human-machine. As shown in FIG. 9, the degree of synchronization state of the human-machine is the same as that of FIG. 8, and the temporal resolution is selected to be not a single breathing cycle, generally greater than one. The duration of the period, for example, 1h; the number in the cell indicates the number of occurrences of the degree of synchronization of each type of human-machine corresponding to the unit time, thereby qualitatively indicating the degree of synchronization of the human-machine.

According to the trend table shown in FIG. 9, the trend of the degree of synchronization state of various types of human-machines can be displayed in the form of a line graph, and FIG. 10 shows the trend of the degree of synchronization of various types of human-machines, as shown in FIG. As shown, the trend graph can more intuitively reflect the trend of the degree of synchronization of various types of human-machines over time in the trend duration.

Further, it is possible to compare the trend of the degree of synchronization of various types of human-machine synchronization states within the trend duration, and FIG. 11 shows a comparison trend of the trend of the degree of synchronization of various types of human-machines, as shown in FIG. In the same coordinate system, the graph shows the degree of synchronization of each type of man-machine synchronization with time, so that the medical staff can conduct comparative analysis and intuitively understand the trend of the degree of synchronization of human-machines, so as to judge whether the ventilation setting is reasonable. The patient's condition is evaluated, wherein the fold line 1 represents the inspiratory trigger and the end of the inhalation is too early, the fold line 2 represents the inspiratory trigger too early and the inspiratory end delay, the fold line 3 represents the human-machine synchronization state, and the fold line 4 represents the inspiratory trigger. Delay and inhalation end too early, and line 5 represents the inspiratory trigger and inspiration end delay. In practical applications, different lines can be distinguished by different colors.

Preferably, for the two-dimensional trend point map shown in FIG. 4, at least two periods of time can be selected by the cursor, and a difference comparison analysis diagram of the synchronization state of the human-machine synchronization state of the at least two periods of time is displayed on the display, and the difference comparison analysis graph can be a data comparison analysis table including a degree of synchronization of the human-machine synchronization state of the at least two periods of time, a comparison pie chart of the degree of synchronization of the human-machine synchronization state of the at least two periods of time, a three-dimensional distribution map corresponding to the at least two periods of time, and the at least two At least one of the three-dimensional profiles of the segment time in the same coordinate system, but is not limited to these representations.

Specifically, taking two time periods as an example, FIG. 12 shows a schematic diagram of selecting a time period in a two-dimensional trend point map. As shown in FIG. 12, vertical lines a1 and b1 are time-segment cursors, respectively indicating time. The start time and end time of the segment 1, the vertical lines a2 and b2 are the cursors of the time segment 2, respectively indicating the start time and the end time of the time segment 2, and the cursor passing through the time segment 1 and the time segment 2 can be from the second Any two periods of time are selected from the dimension trend map to compare and analyze the degree of synchronization between the two machines. Optionally, the position where the cursor stops can display the difference between the inhalation trigger difference and the end of the inhalation end corresponding to the position. For example, the cursor b1 in FIG. 12 stops at 2017/10/20 17:10:00. At the coordinate point of the corresponding degree of inhalation trigger difference, the degree of inspiratory trigger difference of the time is displayed as -10%, and the inspiratory end of the time is displayed at the coordinate point of the corresponding inhalation end difference degree. The difference is 38%. Further, as shown in FIG. 12, the operation menu of the cursor of the time period 1 and the operation menu of the cursor of the time period 2 can also be displayed on the display interface, and the operations of switching and controlling the two cursors can be realized through the operation menu.

In FIG. 12, the time segment 1 is selected from 2017/10/20 17:00:00 to 2017/10/20 17:10:00 by the cursor of time period 1 and the cursor of time period 2, and time period 2 is 2017. /10/20 17:20:00 to 2017/10/20 17:30:00, the comparative analysis of the degree of synchronization between man and machine during these two periods can be compared with data comparison analysis table, comparison pie chart, three-dimensional distribution Graphs, three-dimensional contrast maps, etc. show comparative analysis results. In this way, when the medical staff judges the ventilating system or the patient through appropriate interventions through the human-machine synchronization state information of the time period 1 to determine the ventilating setting is unreasonable, the human-machine synchronization of the time period 2 is synchronized. The comparison of the status information with the human-machine synchronization status information of time period 1 can help determine whether the interventions implemented by the medical staff are correct and effective, thereby providing reference information for the formulation of the ventilation strategy, effectively helping the medical personnel to set the ventilation parameters and evaluating the patient. The condition further improves the effectiveness of ventilation therapy and patient comfort.

FIG. 13 shows a data comparison analysis table of the degree of human-machine synchronization state of any two periods, as shown in FIG. 13, with time period 1 as 2017/10/20 17:00:30 to 2017/10/20 17: 10:32 and time period 2 are 2017/10/20 17:20:30 to 2017/10/20 17:30:32, for example, the number of breathing cycles in these two periods is 60, the duration is 10min; In time period 1, by analyzing and counting the number of invalid triggers, double triggers, automatic triggers and premature switchings occurring in 60 breathing cycles, the number of unsynchronized times is 12 times, accounting for 20%, corresponding to the man-machine. The number of synchronization is 48, accounting for 80%, and the probability of human-machine asynchronous synchronization (AI) is 20%. In time period 2, the number of unsynchronized human-machines is 6 times, accounting for 10%, corresponding to the man-machine. The number of synchronizations is 54 times, accounting for 90%, and the probability of human-machine asynchronous synchronization (AI) is also 10%. Through comparative analysis, it can be seen that there is a respiratory abnormality in time period 1, and after the medical staff implements the intervention measures, the probability of human-machine asynchronousness is significantly reduced in time period 2, and the system is basically in the state of human-machine synchronization, indicating the intervention of medical personnel. The measures are correct and effective.

The comparative analysis chart of the two time periods can also be displayed in the form of a comparative pie chart, and FIG. 14 shows a comparative pie chart of the degree of synchronization of the human-machine state at any two time periods, as shown in FIG. In the figure, the types of human-machine synchronization state are represented by different colors, and the area occupied by each color in the entire pie chart represents the proportion of the type of human-machine synchronization state represented by the color in the total number of respiratory cycles. Optionally, the contrasting pie chart interface can also directly display the probability of human-machine out-of-synchronization by numbers, characters and/or characters, for example, “AI: 20%” and “AI: 10%” shown in FIG. 14 So that the medical staff can more intuitively understand the degree of synchronization of the human-machine.

The comparison analysis diagram of the two time periods may also be displayed in the form of a three-dimensional distribution diagram shown in FIG. 6. FIG. 15 shows a three-dimensional distribution diagram of the degree of synchronization of the human-machine corresponding to any two periods of time, as shown in FIG. With time period 1 as 2017/10/20 17:00:30~2017/10/20 17:10:32 and time period 2 is 2017/10/20 17:20:30 to 2017/10/20 17: In the case of 30:32, in time period 1, some points are outside the shaded area, indicating that the degree of unsynchronized man-machines corresponding to these points is beyond the allowable range of human-computer unsynchronization. At this time, medical personnel are required to select appropriate interventions. Interventions; after the intervention of medical personnel, at time 2, each point is basically within the shaded area, indicating that the time period is in a state of synchronization between humans and machines, further indicating that the intervention of the medical staff for time period 1 is correct and effective. , thereby improving the comfort level of the patient.

Further, the three-dimensional distribution map corresponding to the two periods shown in FIG. 15 may represent a three-dimensional contrast distribution map in the same coordinate system, and FIG. 16 shows a three-dimensional contrast distribution of the degree of human-machine synchronization state in any two periods. Figure, wherein the dotted circle E represents the distribution point of the time period 1, and the dotted circle F represents the distribution point of the time period 2, where the distribution points are circled with E and F only for the convenience of distinction and description, and are not intended to limit the present invention, In practical applications, different colors can be used to distinguish the points corresponding to the two time segments.

The various trend graphs, maps and analysis graphs described above can be displayed separately on the display screen, or can be displayed on the monitor screen in any combination, which provides tools and kanban for analysis and comparison. The monitoring and analysis of the synchronization of human-machines enables medical personnel to visually observe the synchronization of human-machines, thereby assisting medical personnel in setting ventilation parameters, assessing the patient's condition, etc., and implementing appropriate interventions to improve patient comfort. .

The ventilation system and the respiratory synchronization monitoring method and device provided by the embodiments of the present invention calculate the human-machine synchronization state information according to the obtained ventilation parameter and the patient's respiratory trigger information, and display the human-machine synchronization state information, thereby being intuitive The ground shows the degree of unsynchronized man-machines so that doctors can choose the appropriate intervention accordingly. The human-machine synchronization state information may include a degree of inhalation trigger difference and a degree of inhalation end difference, and may further include one or more of a chart, a number, a color, a character, and the like for characterizing the degree of unsynchronization of the human-machine; Visually displaying the synchronization information of the human-machine through at least one of text, data, table, trend, distribution, and analysis, providing the medical staff with tools and kanban for analysis and comparison, enabling medical personnel to visually observe And to understand the severity of the unsynchronized man-machine, and then help the medical staff to determine whether the ventilation setting is reasonable, to assess the patient's condition, etc., thereby providing a reference for the formulation and adjustment of the ventilation strategy, and assisting the medical staff to select appropriate interventions to achieve Reduce or eliminate the purpose of human-computer out of sync, improve the effectiveness of ventilation therapy and patient comfort, and help reduce mechanical ventilation time.

Those skilled in the art can understand that all or part of the functions of the various methods in the above embodiments may be implemented by hardware or by a computer program. When all or part of the functions in the above embodiments are implemented by a computer program, the program may be stored in a computer readable storage medium, and the storage medium may include: a read only memory, a random access memory, a magnetic disk, an optical disk, a hard disk, etc. The computer executes the program to implement the above functions. For example, the program is stored in the memory of the device, and when the program in the memory is executed by the processor, all or part of the above functions can be realized. In addition, when all or part of the functions in the above embodiment are implemented by a computer program, the program may also be stored in a storage medium such as a server, another computer, a magnetic disk, an optical disk, a flash disk or a mobile hard disk, and may be saved by downloading or copying. The system is updated in the memory of the local device, or the system of the local device is updated. When the program in the memory is executed by the processor, all or part of the functions in the above embodiments may be implemented.

The invention has been described above with reference to specific examples, which are merely intended to aid the understanding of the invention and are not intended to limit the invention. For the person skilled in the art to which the invention pertains, several simple derivations, variations or substitutions can be made in accordance with the inventive concept.

Claims

A ventilation system, comprising:

a gas flow providing device for generating a ventilating gas stream;

Breathing line

a patient interface that communicates with the airflow providing device through the breathing circuit and is attached to the patient to deliver the ventilation airflow generated by the airflow providing device to the airway of the patient;

a ventilation detecting device disposed on the breathing circuit or the patient interface for detecting ventilation parameters;

a patient detecting device for detecting respiratory trigger information of the patient;

a data processing device, configured to acquire ventilation parameters and respiratory trigger information, and calculate human-machine synchronization state information according to the ventilation parameters and respiratory trigger information;

A human-machine interaction device includes a display for displaying human-machine synchronization status information output by the data processing device.
The system according to claim 1, wherein said human-machine synchronization state information comprises a degree of inhalation trigger difference and a degree of inhalation end difference.
The system according to claim 2, wherein said data processing means obtains a time at which the patient inhales the trigger and a time at which the inhalation ends based on the collected breath trigger information; and the data processing device obtains the ventilation based on the collected ventilation parameter The moment of inhalation triggering of the system and the moment of inspiration.
The system of claim 2, wherein the human-machine interaction device displays man-machine synchronization status information via at least one of text, data, a table, a trend graph, a profile, and an analysis graph.
The system according to claim 4, wherein said trend graph is a distribution of degrees of synchronization of human-machines in respective predetermined time periods along a time axis;

The distribution map is a three-dimensional distribution map between the degree of difference in inhalation triggering, the degree of difference in inhalation end, and time in any period of time;

The analysis chart includes a human-machine synchronization state degree analysis map in a selected time period and/or a difference comparison analysis diagram of the human-machine synchronization state of at least two periods of time.
The system of any of claims 1-5, wherein the ventilation parameter comprises at least one of a pressure, a flow rate, and a volume waveform, the respiratory trigger information comprising a respiratory mechanics parameter or a respiratory electrical parameter.
A respiratory synchronization monitoring method, comprising:

Obtain ventilation parameters and respiratory trigger information;

Calculating man-machine synchronization state information according to ventilation parameters and breathing trigger information;

Outputs the HMI synchronization status information to the display for display.
The method according to claim 7, wherein said human-machine synchronization state information comprises a degree of inhalation trigger difference and a degree of inhalation end difference.
The method of claim 8, wherein after the obtaining the ventilation parameter and the respiratory trigger information, the method further comprises:

Obtaining a moment of the patient's inhalation trigger and a moment of inhalation end according to the collected respiratory trigger information;

The time of the inspiratory trigger of the ventilation system and the time of inhalation end are obtained based on the collected ventilation parameters.
The method of claim 8, wherein the outputting the human-machine synchronization status information to the display for display comprises: displaying the human-machine by at least one of text, data, a table, a trend graph, a profile, and an analysis graph Synchronization status information.
The method according to claim 10, wherein said trend graph is a distribution of degrees of synchronization of human-machines in respective predetermined time periods along a time axis;

The distribution map is a three-dimensional distribution map between the degree of difference in inhalation triggering, the degree of difference in inhalation end, and time in any period of time;

The analysis chart includes a human-machine synchronization state degree analysis map of the selected time and/or a difference comparison analysis diagram of the human-machine synchronization state of at least two periods of time.
A respiratory synchronization monitoring device, comprising:

Obtaining a module, configured to obtain ventilation parameters and respiratory trigger information;

a calculation module, configured to calculate human-machine synchronization state information according to ventilation parameters and respiratory trigger information;

An output module for outputting human-machine synchronization status information to the display for display.
The apparatus according to claim 12, wherein said human-machine synchronization state information includes a degree of inhalation trigger difference and a degree of inhalation end difference.
The device according to claim 13, wherein the calculation module is further configured to obtain a time of the patient's inhalation trigger and a time of inhalation end according to the collected respiratory trigger information, and obtain the ventilation system according to the collected ventilation parameter. The moment of inhalation trigger and the moment of inspiration.
The device according to claim 12, wherein the output module is specifically configured to output human-machine synchronization status information to the display, and cause the display to pass at least one of text, data, a table, a trend graph, a profile, and an analysis graph. Display man-machine synchronization status information.
The apparatus according to claim 15, wherein said trend graph is a distribution of degrees of synchronization of human-machines in respective predetermined time periods along a time axis;

The distribution map is a three-dimensional distribution map between the degree of difference in inhalation triggering, the degree of difference in inhalation end, and time in any period of time;

The analysis chart includes a human-machine synchronization state degree analysis map of the selected time and/or a difference comparison analysis diagram of the human-machine synchronization state of at least two periods of time.
A computer readable storage medium, comprising a program executable by a processor to implement the method of any one of claims 7-11.