WO2019194512A1 - Optical coherence brain catheter for cerebrovascular surgery, and use method therefor - Google Patents

Optical coherence brain catheter for cerebrovascular surgery, and use method therefor Download PDF

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Publication number
WO2019194512A1
WO2019194512A1 PCT/KR2019/003822 KR2019003822W WO2019194512A1 WO 2019194512 A1 WO2019194512 A1 WO 2019194512A1 KR 2019003822 W KR2019003822 W KR 2019003822W WO 2019194512 A1 WO2019194512 A1 WO 2019194512A1
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Prior art keywords
catheter
optical
cerebrovascular surgery
cerebrovascular
passage
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PCT/KR2019/003822
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French (fr)
Korean (ko)
Inventor
이종하
김창현
이창영
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계명대학교 산학협력단
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Publication of WO2019194512A1 publication Critical patent/WO2019194512A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00165—Optical arrangements with light-conductive means, e.g. fibre optics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/313—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/313—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes
    • A61B1/3137—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes for examination of the interior of blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A61M25/0012—Making of catheters or other medical or surgical tubes with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M25/005—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22001—Angioplasty, e.g. PCTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M2025/0019—Cleaning catheters or the like, e.g. for reuse of the device, for avoiding replacement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M2025/0042—Microcatheters, cannula or the like having outside diameters around 1 mm or less

Definitions

  • the present invention relates to an optical coherent catheter for intravascular surgery and a method of using the same, and more particularly, to an optical coherent brain catheter for cerebrovascular surgery and a method of using the same.
  • Catheter is one of the common names of tubular instruments and means a tubular device for insertion into an organ with body cavity or lumen.
  • the catheter is used for the discharge of debris in the body cavity or various organs, the aspiration of the cleaning perfusion solution, the measurement of cardiovascular behavior or central venous pressure, the infusion of drugs or contrast agents, etc. Can be configured in the form.
  • intravascular imaging catheter used for the diagnosis of cardiovascular disease
  • intravascular ultrasound, intravascular near-infrared imaging technology, and intravascular optical interference tomography have been commercialized and used in clinical practice.
  • Intravascular optical coherence tomography which is used for intravascular optical coherence tomography, is a catheter-type device that inserts light into a blood vessel, sends light to the blood vessel, and analyzes the returning light to acquire a tomographic image of the blood vessel.
  • Early vascular optical coherence tomography was not widely used because its speed was not as fast as the level of intravascular ultrasound, but recently developed second generation vascular optical coherence tomography technique is more than 10 times faster, resulting in intravascular imaging within seconds. You can shoot. Because light is used, images are obtained by flushing a solution of saline and angiography to minimize the effects of blood.
  • ischemic cerebral infarction is due to atherosclerotic cerebrovascular stenosis and its associated thrombosis or thromboembolism due to cardiac and aortic disease.
  • cerebrovascular stenosis the causes, progression, and infarction patterns vary according to the components of atherosclerotic plaques, so it is very important to know the exact information about the treatment strategy.
  • OCT catheter C7-XR dragonfly imaging catheter, OCT catheter
  • OCT catheter is an imaging device capable of viewing cross-sectional images of coronary stenosis. He is treating stenosis in a more accurate and safe way.
  • OCT catheter is flexible but poorly accessible.
  • FIG. 1 is a diagram illustrating a state in which an OCT catheter is inserted into a coronary artery.
  • the coronary artery is relatively inflexible after the induction catheter is inserted and thus can be accessed as a flexible OCT catheter, but there are two problems in applying the conventional OCT catheter to the cerebrovascular vessel. have. First, it is not well accessible for cerebrovascular vessels that have to go through three to four severe curves.
  • 2 is a diagram showing the severe bending of the cerebrovascular. As shown in FIG. 2, there is severe curvature in the cerebrovascular system.
  • FIG. 3 is a diagram illustrating an OCT catheter for cardiac medicine
  • FIG. 4 is a diagram illustrating an OCT catheter for cardiac medicine.
  • the catheter comes out in front of the OCT lens, there is an inconvenience that the catheter must be inserted into the blood vessel as a whole for the procedure to the required site.
  • Korean Patent Publication No. 10-1397272 name of the invention: a comprehensive imaging catheter system and an image processing system.
  • an object of the present invention is to provide an optical coherent brain catheter for cerebrovascular surgery and a method of using the catheter, thereby enabling a necessary procedure even if less catheter is inserted into the blood vessel.
  • another object of the present invention is to provide an optical coherent brain catheter for cerebrovascular surgery and a method of using the catheter, which can be suitably applied to cerebrovascular vessels by shortening the distal length of the catheter. .
  • an optical coherence brain catheter for cerebrovascular surgery According to a feature of the present invention for achieving the above object, an optical coherence brain catheter for cerebrovascular surgery,
  • An optical path 200 surrounded by the surface 100 and serving as a passage through which a light source and an optical cable pass;
  • wire passage 300 as a passage separate from the optical passage 200, the wire passage 300 is surrounded by the surface 100 and acts as a passage through which the wire passes.
  • the surface 100 Preferably, the surface 100,
  • the twisted portion 120 More preferably, the twisted portion 120,
  • Metal yarn made of stainless steel may be twisted.
  • the surface 100 Preferably, the surface 100,
  • It may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
  • the optical path 200 may have a wider cross-sectional area than the wire path 300.
  • the optical path 200 may further include a separator 400 which serves to distinguish the wire path 300.
  • the endothelial integrated membrane 410 may be formed by combining with the endothelial 130 of the surface 100.
  • the separator 400 Preferably, the separator 400,
  • It may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
  • the end of the wire passage 300 may further include a washing unit for catheter cleaning.
  • a catheter including an optical path 200 and a wire path 300 is inserted into a blood vessel;
  • the surface 100 Preferably, the surface 100,
  • the twisted portion 120 More preferably, the twisted portion 120,
  • Metal yarn made of stainless steel may be twisted.
  • the surface 100 Preferably, the surface 100,
  • It may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
  • the optical path 200 may have a wider cross-sectional area than the wire path 300.
  • the optical path 200 may further include a separator 400 which serves to distinguish the wire path 300.
  • the endothelial integrated membrane 410 may be formed by combining with the endothelial 130 of the surface 100.
  • the separator 400 Preferably, the separator 400,
  • It may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
  • the end of the wire passage 300 may further include a washing unit for catheter cleaning.
  • the shaft tube of the catheter is composed of a double hole of an optical path and a wire path, so that the micro wire is in a different direction from the optical cable.
  • the surface of the catheter may be configured to include a twisted portion, thereby increasing accessibility.
  • optical coherence brain catheter for the cerebrovascular surgery proposed in the present invention proposes a method of using the same, by shortening the distal length of the catheter, it can be appropriately applied to the cerebrovascular.
  • FIG. 1 is a view showing the insertion of the OCT catheter in the coronary arteries.
  • FIG. 2 is a diagram showing the severe bending of cerebrovascular.
  • Figure 3 shows an OCT catheter for cardiology.
  • FIG. 4 is a diagram illustrating an OCT catheter for cardiac medicine.
  • FIG. 5 is a block diagram of an optical coherent brain catheter for intravascular cerebrovascular surgery according to one embodiment of the present invention.
  • Figure 6 is a view showing the surface of the catheter portion in the optical coherence brain catheter for intravascular cerebrovascular surgery according to an embodiment of the present invention.
  • FIG. 7 is a cross-sectional view of the catheter according to the position in the optical coherence brain catheter for intravascular cerebrovascular surgery according to another embodiment of the present invention.
  • FIG. 8 is a diagram illustrating an endothelial integrated membrane in an optical coherent brain catheter for cerebrovascular surgery according to another embodiment of the present invention.
  • FIG. 9 is a view showing a state using an optical coherence brain catheter for intravascular cerebrovascular surgery according to an embodiment of the present invention.
  • FIG. 10 is a flow chart of a method of using an optical coherent brain catheter for cerebrovascular surgery.
  • S100 a step in which a catheter including an optical path and a wire path is inserted into a blood vessel
  • step S200 performing optical coherence tomography by passing the optical cable through the optical path of the catheter inserted in step S100
  • FIG. 5 is a block diagram of an optical coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention.
  • the optically coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention includes a light source and an optical cable surrounded by a surface 100 and a surface 100 constituting a shaft tube of the catheter. It may be configured to include a light path 200 that acts as a passage, a separate path from the light path 200, and a wire path 300 that acts as a path through which the wire is surrounded by the surface 100.
  • FIG. 6 is a view illustrating the surface 100 of a shaft tube (conduit, shaft tube) in an optical coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention.
  • Figure 6 (a) is a side view of the catheter 10
  • (b) is a view showing a cross section of the catheter.
  • the twisted portion 120 may be made of a stainless steel material according to the embodiment.
  • OTC catheter for conventional cardiovascular treatment has a problem that the accessibility is poor because there is no portion (Braided) on the surface.
  • the optically coherent brain catheter 10 for intravascular cerebrovascular surgery according to an embodiment of the present invention includes the twisted portion 120, when the catheter is inserted into the severely curved cerebrovascular vessel, the force is better received. To increase the accessibility of the catheter.
  • the outer shell 110 and the inner shell 130 of the catheter surface 100 may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
  • the present invention is not limited to the above materials.
  • the optically coherent brain catheter 10 for cerebrovascular surgery is a separator that serves to distinguish between the optical path 200 and the wire path 300. 400 may be configured to further include.
  • the optical path 200 may have a wider cross-sectional area than the wire path 300.
  • FIG. 8 is a diagram illustrating an endothelial integrated membrane in an optical coherence brain catheter for cerebrovascular surgery according to another embodiment of the present invention.
  • the separator 400 may be combined with the endothelial 130 of the catheter conduit surface 100 to form an endothelial integral membrane 410.
  • the material of the separator 400 may be made of polyethylene, polypropylene, which is harmless to the human body, but is not limited thereto.
  • the microwire and the light source can be made to come out in different directions.
  • the microwires can be made to come out to the far side, rather than short to the side at the end of the catheter.
  • the light source can be inserted into a position separate from the micro wires, and the light source does not need to be inserted until the induction wire is inserted. Accordingly, the entire catheter is not integrally inserted into the blood vessel, and the light source is inserted only at a desired portion separately from the degree of catheter insertion as needed, thereby enabling more accessible and convenient procedures.
  • FIG. 9 is a diagram illustrating the use of an optical coherent brain catheter for cerebrovascular surgery.
  • 9 (a) is a diagram illustrating a state of surgery using an existing OCT catheter.
  • the conventional catheter includes a 20 mm protruding portion in front of the OCT lens (light source), so that the catheter passes through the lesion site in the blood vessel to irradiate the lesion site. It shall be inserted further by 20 mm.
  • Figure 9 (b) is a diagram illustrating the operation using an optical coherence brain catheter for intravascular cerebrovascular surgery according to an embodiment of the present invention.
  • the micro wires and the light source (OCT lens) may be emitted in different directions, so that the light source and the catheter tip may be in the same plane. Accordingly, unlike the conventional catheter, it is possible to insert less 20mm unlike the conventional catheter for the procedure, the lesion site required to increase the accessibility.
  • the distal portion is 50 mm long.
  • the optical coherence brain catheter 10 for intravascular cerebrovascular surgery is to shorten the distal length of the catheter, to be appropriately applied to the cerebrovascular.
  • the optical coherent brain catheter 10 for cerebrovascular surgery may further include a washing unit for catheter cleaning at the end of the wire passage 300. If the catheter is made of a single hole, all of the light source, the optical cable portion should be washed to clean the catheter, but the catheter is the same as the optical coherent brain catheter 10 for intravascular cerebrovascular surgery according to an embodiment of the present invention. In the case of a double hole, the washing part is included only in the portion of the wire passage 300 through which the micro wires (induction wires) pass, whereby the catheter can be washed more conveniently.
  • the washing unit described above may clean the catheter by saline flushing into the catheter.
  • FIG. 10 is a flowchart illustrating a method of using an optical coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention.
  • a method of using an optical coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention includes a light source surrounded by a surface 100 and a surface 100 constituting a catheter conduit.
  • a method of using a catheter comprising an optical path 200 acting as a passage through which an optical cable passes, and a wire path 300 acting as a passage through which the wire is surrounded by the surface 100 as a path separate from the optical path,
  • the catheter including the passage 200 and the wire passage 300 is inserted into the blood vessel (S100), and the optical coherence tomography by passing the light source and the optical cable through the optical passage 200 of the catheter inserted in step S100 It includes the step of performing.
  • the microtube is formed so that the shaft tube of the catheter is composed of a double hole of an optical channel and a wire channel
  • the surface of the catheter may be configured to include a twisted portion, thereby increasing accessibility.
  • by shortening the distal length of the catheter it can be appropriately applied to cerebrovascular.

Abstract

According to an optical coherence brain catheter for cerebrovascular surgery and a use method therefor, which are presented in the present invention, a shaft tube of a catheter has an optical passage and a wire passage as double holes, thereby allowing a microwire to come out in a direction different from that of an optical cable, and thus a necessary procedure is enabled even if the catheter is inserted into a blood vessel not as deeply.

Description

뇌혈관내 수술을 위한 광간섭성 브레인 카테터, 및 그 이용방법Optically coherent brain catheter for cerebrovascular surgery, and its use
본 발명은 혈관내 수술을 위한 광간섭성 카테터 및 그 이용방법에 관한 것으로서, 보다 구체적으로는 뇌혈관내 수술을 위한 광간섭성 브레인 카테터 및 그 이용방법에 관한 것이다.The present invention relates to an optical coherent catheter for intravascular surgery and a method of using the same, and more particularly, to an optical coherent brain catheter for cerebrovascular surgery and a method of using the same.
카테터(catheter)는 관 모양 기구의 일반적 명칭의 하나로서, 체강 또는 내강이 있는 장기 내로 삽입하기 위한 튜브형의 장치를 의미한다. 카테터는 체강이나 각종 기관 내의 저류물의 배출, 세정용 관류액의 흡인, 심혈행동태나 중심정맥압 등의 측정, 약물이나 조영제의 체내 주입 등의 용도로 이용되고 있으며, 이러한 용도에 따라 다양한 재질, 크기, 형태로 구성될 수가 있다.Catheter is one of the common names of tubular instruments and means a tubular device for insertion into an organ with body cavity or lumen. The catheter is used for the discharge of debris in the body cavity or various organs, the aspiration of the cleaning perfusion solution, the measurement of cardiovascular behavior or central venous pressure, the infusion of drugs or contrast agents, etc. Can be configured in the form.
심혈관 질환의 진단에 사용되는 혈관 영상 카테터의 종래 기술로는 혈관 내 초음파, 혈관 내 근적외선 영상기술, 혈관 내 광 간섭 단층촬영기가 상용화되어 임상에서 활용되고 있다.As a conventional technique of vascular imaging catheter used for the diagnosis of cardiovascular disease, intravascular ultrasound, intravascular near-infrared imaging technology, and intravascular optical interference tomography have been commercialized and used in clinical practice.
혈관 내 광간섭 단층촬영기에 사용되는 혈관 내 광 간섭 단층촬영기술은 카테터 형태의 기기로 혈관에 삽입되어 빛을 혈관으로 보내고, 돌아오는 빛을 분석하여 혈관의 단층 영상을 획득하는 기술을 말한다. 초기 혈관 내 광 간섭 단층촬영기는 속도가 혈관 내 초음파 수준으로 빠르지 않아 널리 활용되지 못하였으나 최근에 개발된 2세대 혈관 내 광 간섭 단층촬영기술은 속도가 10배 이상 형성되어, 수 초 이내에 혈관 내 영상을 촬영할 수 있다. 빛을 이용하기 때문에 혈액의 영향을 최소화하기 위해 식염수와 혈관 조영제를 혼합한 용액을 플러싱(Flushing) 하면서 영상을 얻는다.Intravascular optical coherence tomography, which is used for intravascular optical coherence tomography, is a catheter-type device that inserts light into a blood vessel, sends light to the blood vessel, and analyzes the returning light to acquire a tomographic image of the blood vessel. Early vascular optical coherence tomography was not widely used because its speed was not as fast as the level of intravascular ultrasound, but recently developed second generation vascular optical coherence tomography technique is more than 10 times faster, resulting in intravascular imaging within seconds. You can shoot. Because light is used, images are obtained by flushing a solution of saline and angiography to minimize the effects of blood.
허혈성 뇌경색의 주요 원인은 죽상동맥경화성 뇌혈관협착과 이에 동반된 혈전증이나 심장 및 대동맥질환에 의한 혈전색전증에 기인하며, 경동맥과 두개강내 혈관의 협착이 약 30~40%를 차지한다. 뇌혈관협착증에서 죽상경화판의 구성성분에 따라 원인, 진행과정, 뇌경색 발생형태가 달라지므로 이에 대한 정보를 정확하게 아는 것이 환자의 치료전략에 매우 중요하다.The main cause of ischemic cerebral infarction is due to atherosclerotic cerebrovascular stenosis and its associated thrombosis or thromboembolism due to cardiac and aortic disease. In cerebrovascular stenosis, the causes, progression, and infarction patterns vary according to the components of atherosclerotic plaques, so it is very important to know the exact information about the treatment strategy.
심장내과 영역에서는 관상동맥 협착증의 단면 영상을 잘 볼 수 있는 영상기기인 광간섭성 단층촬영을 이용한 카테터(C7-XR dragonfly imaging catheter, OCT 카테터)를 이용하여 혈관 내 수술하기 전후의 단면영상을 검사하여 좀 더 정확하고 안전한 방법으로 협착증을 치료하고 있다. OCT 카테터는 유연하지만, 접근성이 좋지는 않다.In the cardiac medicine area, cross-sectional images before and after endovascular surgery are performed using a catheter (C7-XR dragonfly imaging catheter, OCT catheter), which is an imaging device capable of viewing cross-sectional images of coronary stenosis. He is treating stenosis in a more accurate and safe way. OCT catheter is flexible but poorly accessible.
도 1은 관상동맥에 OCT카테터를 삽입하는 모습을 도시한 도면이다. 도 1에 도시된 바와 같이, 관상동맥은 유도용 카테터가 들어간 이 후에 비교적 굴곡의 정도가 심하지 않아서 유연한 OCT 카테터로도 접근이 가능하지만, 기존의 OCT 카테터를 뇌혈관에 적용하기에는 2가지의 문제점이 있다. 첫째로, 3-4회 정도의 심한 굴곡(Curve)을 지나가야 하는 뇌혈관에 적용하기는 접근성이 좋지 않다. 도 2는 뇌혈관의 심한 굴곡을 보여주기 위해 도시한 도면이다. 도 2에 도시된 바와 같이 뇌혈관에는 심한 굴곡이 있다.1 is a diagram illustrating a state in which an OCT catheter is inserted into a coronary artery. As shown in FIG. 1, the coronary artery is relatively inflexible after the induction catheter is inserted and thus can be accessed as a flexible OCT catheter, but there are two problems in applying the conventional OCT catheter to the cerebrovascular vessel. have. First, it is not well accessible for cerebrovascular vessels that have to go through three to four severe curves. 2 is a diagram showing the severe bending of the cerebrovascular. As shown in FIG. 2, there is severe curvature in the cerebrovascular system.
둘째로 OCT 카테터의 센서 앞부분으로 카테터가 2㎝ 정도 튀어나와 있어서 관상동맥용 카테터를 뇌혈관에 적용하기에는 어려움이 있다. 도 3은 심장내과용 OCT 카테터를 도시한 도면이고, 도 4는 심장내과용 OCT 카테터를 도식화한 도면이다. 도 3 및 도 4에 도시된 바와 같이, OCT 렌즈 앞쪽으로 카테터가 나와있어, 필요한 부위에의 시술을 위해서는 카테터를 전체적으로 더 혈관에 삽입해야 하는 불편함이 있다.Secondly, the catheter protrudes about 2cm in front of the sensor of the OCT catheter, making it difficult to apply the coronary catheter to the cerebrovascular vessel. FIG. 3 is a diagram illustrating an OCT catheter for cardiac medicine, and FIG. 4 is a diagram illustrating an OCT catheter for cardiac medicine. As shown in Figures 3 and 4, the catheter comes out in front of the OCT lens, there is an inconvenience that the catheter must be inserted into the blood vessel as a whole for the procedure to the required site.
광간섭성 카테터와 관련된 선행기술로서는, 대한민국 등록특허공보 제10-1397272호(발명의 명칭: 포괄적인 영상화 카테터 시스템 및 영상 처리 시스템)가 존재한다.As a related art related to an optical coherent catheter, there is a Korean Patent Publication No. 10-1397272 (name of the invention: a comprehensive imaging catheter system and an image processing system).
본 발명은 기존에 제안된 방법들의 상기와 같은 문제점들을 해결하기 위해 제안된 것으로서, 카테터의 샤프트 튜브가 광통로와 와이어통로의 이중구멍으로 구성되도록 하여, 마이크로 와이어가 광케이블과 다른 방향으로 나올 수 있도록 함으로써, 카테터를 혈관에 덜 삽입해도 필요한 시술이 가능하도록 하는 뇌혈관내 수술을 위한 광간섭성 브레인 카테터 및 그 이용방법을 제공하는 것을 그 목적으로 한다.The present invention has been proposed to solve the above problems of the conventionally proposed methods, so that the shaft tube of the catheter is composed of a double hole of the optical passage and the wire passage, so that the micro wire can come out in a different direction from the optical cable. Accordingly, an object of the present invention is to provide an optical coherent brain catheter for cerebrovascular surgery and a method of using the catheter, thereby enabling a necessary procedure even if less catheter is inserted into the blood vessel.
또한, 본 발명은, 카테터의 표면이 꼬임 부분을 포함하여 구성되도록 함으로써, 접근성을 증가시킬 수 있도록 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터 및 그 이용방법을 제공하는 것을 다른 목적으로 한다.It is another object of the present invention to provide an optical coherent brain catheter for cerebrovascular surgery and a method of using the catheter, wherein the surface of the catheter includes a twisted portion, thereby increasing accessibility. .
뿐만 아니라, 본 발명은, 카테터의 원위부 길이를 짧게 함으로써, 뇌혈관에 적절하게 적용할 수 있도록 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터 및 그 이용방법을 제공하는 것을 또 다른 목적으로 한다.In addition, another object of the present invention is to provide an optical coherent brain catheter for cerebrovascular surgery and a method of using the catheter, which can be suitably applied to cerebrovascular vessels by shortening the distal length of the catheter. .
상기한 목적을 달성하기 위한 본 발명의 특징에 따른, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터는,According to a feature of the present invention for achieving the above object, an optical coherence brain catheter for cerebrovascular surgery,
카테터의 샤프트 튜브를 구성하는 표면(100);A surface 100 constituting the shaft tube of the catheter;
상기 표면(100)에 둘러싸여 광원과 광케이블이 지나가는 통로로서 작용하는 광통로(200); 및An optical path 200 surrounded by the surface 100 and serving as a passage through which a light source and an optical cable pass; And
상기 광통로(200)와 별개의 통로로서, 상기 표면(100)에 둘러싸여 와이어가 지나가는 통로로서 작용하는 와이어통로(300)를 포함하는 것을 그 구성상의 특징으로 한다.It is characterized in that it comprises a wire passage 300 as a passage separate from the optical passage 200, the wire passage 300 is surrounded by the surface 100 and acts as a passage through which the wire passes.
바람직하게는, 상기 표면(100)은,Preferably, the surface 100,
접근성을 확보하기 위한 꼬임 부분(120)을 포함할 수 있다.It may include a twisted portion 120 to secure accessibility.
더 바람직하게는, 상기 꼬임 부분(120)은,More preferably, the twisted portion 120,
스테인리스강 재질의 금속사가 꼬여서 이루어질 수 있다.Metal yarn made of stainless steel may be twisted.
바람직하게는, 상기 표면(100)은,Preferably, the surface 100,
카테터 도관의 바깥쪽 면을 이루는 외피(110); 및 Envelope 110 constituting the outer side of the catheter conduit; And
카테터 도관의 안쪽 면을 이루는 내피(130)를 포함할 수 있다.It may include an endothelial 130 that forms the inner side of the catheter conduit.
더 바람직하게는, 상기 외피(110) 및 내피(130)는,More preferably, the outer shell 110 and the inner shell 130,
인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어질 수 있다.It may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
바람직하게는,Preferably,
상기 광통로(200)는 상기 와이어통로(300)에 비해 그 단면적이 넓을 수 있다.The optical path 200 may have a wider cross-sectional area than the wire path 300.
바람직하게는,Preferably,
상기 광통로(200)와 상기 와이어통로(300)를 구별하는 역할을 하는 분리막(400)을 더 포함할 수 있다.The optical path 200 may further include a separator 400 which serves to distinguish the wire path 300.
더 바람직하게는, 상기 분리막(400)은,More preferably, the separator 400,
상기 표면(100)의 내피(130)와 결합하여 내피 일체형 분리막(410)을 이룰 수 있다.The endothelial integrated membrane 410 may be formed by combining with the endothelial 130 of the surface 100.
바람직하게는, 상기 분리막(400)은,Preferably, the separator 400,
인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어질 수 있다.It may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
바람직하게는,Preferably,
상기 와이어통로(300)의 끝 부분에 카테터 세척을 위한 세척부를 더 포함할 수 있다.The end of the wire passage 300 may further include a washing unit for catheter cleaning.
또한, 상기한 목적을 달성하기 위한 본 발명의 다른 특징에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터를 이용하는 방법은,In addition, a method of using an optical coherent brain catheter for cerebrovascular surgery according to another aspect of the present invention for achieving the above object,
카테터의 샤프트 튜브를 구성하는 표면(100); 상기 표면(100)에 둘러싸여 광원과 광케이블이 지나가는 통로로서 작용하는 광통로(200); 및 상기 광통로(200)와 별개의 통로로서, 상기 표면(100)에 둘러싸여 와이어가 지나가는 통로로서 작용하는 와이어통로(300)를 포함하는 카테터를 이용하는 방법으로서,A surface 100 constituting the shaft tube of the catheter; An optical path 200 surrounded by the surface 100 and serving as a passage through which a light source and an optical cable pass; And a wire passage 300 which is a separate passage from the optical passage 200 and is surrounded by the surface 100 and serves as a passage through which the wire passes.
(1) 광통로(200)와 와이어통로(300)를 포함하는 카테터가 혈관에 삽입되는 단계; 및(1) a catheter including an optical path 200 and a wire path 300 is inserted into a blood vessel; And
(2) 상기 단계 (1)에서 삽입된 카테터의 상기 광통로(200)에 광원 및 광케이블을 통과시킴으로써 광간섭성 단층촬영을 수행하는 단계를 포함하는 것을 그 구성상의 특징으로 한다.(2) performing optical coherence tomography by passing a light source and an optical cable through the optical path 200 of the catheter inserted in the step (1).
바람직하게는, 상기 표면(100)은,Preferably, the surface 100,
접근성을 확보하기 위한 꼬임 부분(120)을 포함할 수 있다.It may include a twisted portion 120 to secure accessibility.
더 바람직하게는, 상기 꼬임 부분(120)은,More preferably, the twisted portion 120,
스테인리스강 재질의 금속사가 꼬여서 이루어질 수 있다.Metal yarn made of stainless steel may be twisted.
바람직하게는, 상기 표면(100)은,Preferably, the surface 100,
카테터 도관의 바깥쪽 면을 이루는 외피(110); 및 Envelope 110 constituting the outer side of the catheter conduit; And
카테터 도관의 안쪽 면을 이루는 내피(130)를 포함할 수 있다.It may include an endothelial 130 that forms the inner side of the catheter conduit.
더 바람직하게는, 상기 외피(110) 및 내피(130)는,More preferably, the outer shell 110 and the inner shell 130,
인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어질 수 있다.It may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
바람직하게는,Preferably,
상기 광통로(200)는 상기 와이어통로(300)에 비해 그 단면적이 넓을 수 있다.The optical path 200 may have a wider cross-sectional area than the wire path 300.
바람직하게는,Preferably,
상기 광통로(200)와 상기 와이어통로(300)를 구별하는 역할을 하는 분리막(400)을 더 포함할 수 있다.The optical path 200 may further include a separator 400 which serves to distinguish the wire path 300.
더 바람직하게는, 상기 분리막(400)은,More preferably, the separator 400,
상기 표면(100)의 내피(130)와 결합하여 내피 일체형 분리막(410)을 이룰 수 있다.The endothelial integrated membrane 410 may be formed by combining with the endothelial 130 of the surface 100.
바람직하게는, 상기 분리막(400)은,Preferably, the separator 400,
인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어질 수 있다.It may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body.
바람직하게는,Preferably,
상기 와이어통로(300)의 끝 부분에 카테터 세척을 위한 세척부를 더 포함할 수 있다.The end of the wire passage 300 may further include a washing unit for catheter cleaning.
본 발명에서 제안하고 있는 뇌혈관내 수술을 위한 광간섭성 브레인 카테터 및 그 이용방법에 따르면, 카테터의 샤프트 튜브가 광통로와 와이어통로의 이중구멍으로 구성되도록 하여, 마이크로 와이어가 광케이블과 다른 방향으로 나올 수 있도록 함으로써, 카테터를 혈관에 덜 삽입해도 필요한 시술이 가능하도록 할 수 있다.According to the optical coherence brain catheter proposed for the cerebrovascular surgery proposed in the present invention and a method of using the same, the shaft tube of the catheter is composed of a double hole of an optical path and a wire path, so that the micro wire is in a different direction from the optical cable. By allowing them to come out, less catheter can be inserted into the blood vessel, thereby enabling the necessary procedures.
또한, 본 발명에서 제안하고 있는 뇌혈관내 수술을 위한 광간섭성 브레인 카테터 및 그 이용방법에 따르면, 카테터의 표면이 꼬임 부분을 포함하여 구성되도록 함으로써, 접근성을 증가시키도록 할 수 있다.In addition, according to the optical coherence brain catheter for the cerebrovascular surgery proposed in the present invention and a method of using the same, the surface of the catheter may be configured to include a twisted portion, thereby increasing accessibility.
뿐만 아니라, 본 발명에서 제안하고 있는 뇌혈관내 수술을 위한 광간섭성 브레인 카테터 및 그 이용방법에 따르면, 카테터의 원위부 길이를 짧게 함으로써, 뇌혈관에 적절하게 적용하도록 할 수 있다.In addition, according to the optical coherence brain catheter for the cerebrovascular surgery proposed in the present invention and a method of using the same, by shortening the distal length of the catheter, it can be appropriately applied to the cerebrovascular.
도 1은 관상동맥에 OCT카테터를 삽입하는 모습을 도시한 도면.1 is a view showing the insertion of the OCT catheter in the coronary arteries.
도 2는 뇌혈관의 심한 굴곡을 보여주기 위해 도시한 도면.2 is a diagram showing the severe bending of cerebrovascular.
도 3은 심장내과용 OCT 카테터를 도시한 도면.Figure 3 shows an OCT catheter for cardiology.
도 4는 심장내과용 OCT 카테터를 도식화한 도면.4 is a diagram illustrating an OCT catheter for cardiac medicine.
도 5는 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 블록도를 도시한 도면.5 is a block diagram of an optical coherent brain catheter for intravascular cerebrovascular surgery according to one embodiment of the present invention.
도 6은 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터에서 카테터부의 표면 모습을 도시한 도면.Figure 6 is a view showing the surface of the catheter portion in the optical coherence brain catheter for intravascular cerebrovascular surgery according to an embodiment of the present invention.
도 7은 본 발명의 다른 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터에서 위치에 따른 카테터의 단면을 도시한 도면.7 is a cross-sectional view of the catheter according to the position in the optical coherence brain catheter for intravascular cerebrovascular surgery according to another embodiment of the present invention.
도 8은 본 발명의 또 다른 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터에서 내피 일체형 분리막을 도시한 도면.8 is a diagram illustrating an endothelial integrated membrane in an optical coherent brain catheter for cerebrovascular surgery according to another embodiment of the present invention.
도 9는 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터를 이용하는 모습을 도시한 도면.9 is a view showing a state using an optical coherence brain catheter for intravascular cerebrovascular surgery according to an embodiment of the present invention.
도 10은 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법의 흐름도를 도시한 도면.10 is a flow chart of a method of using an optical coherent brain catheter for cerebrovascular surgery.
<부호의 설명><Description of the code>
10: 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터10: optical coherence brain catheter for cerebrovascular surgery according to an embodiment of the present invention
100: 표면100: surface
110: 외피110: sheath
120: 꼬임 부분120: twisted portion
130: 내피130: endothelial
200: 광통로200: light path
300: 와이어통로300: wire passage
400: 분리막400: separator
410: 내피 일체형 분리막410: endothelial membrane
S100: 광통로와 와이어통로를 포함하는 카테터가 혈관에 삽입되는 단계S100: a step in which a catheter including an optical path and a wire path is inserted into a blood vessel
S200: 단계 S100에서 삽입된 카테터의 광통로에 광케이블을 통과시킴으로써 광간섭성 단층촬영을 수행하는 단계S200: performing optical coherence tomography by passing the optical cable through the optical path of the catheter inserted in step S100
이하 첨부된 도면을 참조하여 본 발명이 속하는 기술분야에서 통상의 지식을 가진 자가 본 발명을 용이하게 실시할 수 있도록 바람직한 실시예를 상세히 설명한다. 다만, 본 발명의 바람직한 실시예를 상세하게 설명함에 있어, 관련된 공지 기능 또는 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우에는 그 상세한 설명을 생략한다. 또한, 유사한 기능 및 작용을 하는 부분에 대해서는 도면 전체에 걸쳐 동일한 부호를 사용한다.Hereinafter, exemplary embodiments will be described in detail with reference to the accompanying drawings so that those skilled in the art may easily implement the present invention. However, in describing the preferred embodiment of the present invention in detail, if it is determined that the detailed description of the related known function or configuration may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted. In addition, the same reference numerals are used throughout the drawings for parts having similar functions and functions.
덧붙여, 명세서 전체에서, 어떤 부분이 다른 부분과 ‘연결’되어 있다고 할 때, 이는 ‘직접적으로 연결’되어 있는 경우뿐만 아니라, 그 중간에 다른 소자를 사이에 두고 ‘간접적으로 연결’ 되어 있는 경우도 포함한다. 또한, 어떤 구성요소를 ‘포함’한다는 것은, 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라 다른 구성요소를 더 포함할 수 있다는 것을 의미한다.In addition, throughout the specification, when a part is 'connected' to another part, it is not only 'directly connected' but also 'indirectly connected' with another element in between. Include. In addition, "including" a certain component means that it may further include other components, except to exclude other components unless specifically stated otherwise.
도 5는 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 블록도를 도시한 도면이다. 도 5에 도시된 바와 같이, 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터는 카테터의 샤프트 튜브를 구성하는 표면(100), 표면(100)에 둘러싸여 광원과 광케이블이 지나가는 통로로서 작용하는 광통로(200), 광통로(200)와 별개의 통로로서, 및 표면(100)에 둘러싸여 와이어가 지나가는 통로로서 작용하는 와이어통로(300)를 포함하여 구성될 수 있다.FIG. 5 is a block diagram of an optical coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention. As shown in FIG. 5, the optically coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention includes a light source and an optical cable surrounded by a surface 100 and a surface 100 constituting a shaft tube of the catheter. It may be configured to include a light path 200 that acts as a passage, a separate path from the light path 200, and a wire path 300 that acts as a path through which the wire is surrounded by the surface 100.
도 6은 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터에서 샤프트 튜브(도관, Shaft Tube)의 표면(100) 모습을 도시한 도면이다. 도 6의 (a)는 카테터(10)를 측면에서 바라본 모습을 도시하였으며, (b)는 카테터의 단면을 도시한 도면이다. 도 6에 도시된 바와 같이, 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터에서 표면(100)은, 카테터 도관 바깥쪽의 외피(110), 접근성을 확보하기 위한 꼬임 부분(120), 및 카테터 도관 안쪽의 내피(130)를 포함하여 구성될 수 있다.FIG. 6 is a view illustrating the surface 100 of a shaft tube (conduit, shaft tube) in an optical coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention. Figure 6 (a) is a side view of the catheter 10, and (b) is a view showing a cross section of the catheter. As shown in Figure 6, in the optically coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention, the surface 100, the outer shell 110 of the catheter conduit, twisted to secure access Portion 120 and endothelial 130 inside the catheter conduit.
꼬임 부분(120)은 실시예에 따라서 스테인리스강의 재질로 이루어질 수 있다. 기존의 심혈관 시술용 OTC카테터는 표면에 꼬인 부분(Braided)이 존재하지 않아 접근성이 떨어지는 문제가 있다. 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터(10)가 꼬임 부분(120)을 포함하도록 함으로써, 카테터를 굴곡이 심한 뇌혈관에 삽입할 경우, 힘을 더 잘 받을 수 있도록 하여 카테터의 접근성을 높일 수 있다.The twisted portion 120 may be made of a stainless steel material according to the embodiment. OTC catheter for conventional cardiovascular treatment has a problem that the accessibility is poor because there is no portion (Braided) on the surface. When the optically coherent brain catheter 10 for intravascular cerebrovascular surgery according to an embodiment of the present invention includes the twisted portion 120, when the catheter is inserted into the severely curved cerebrovascular vessel, the force is better received. To increase the accessibility of the catheter.
카테터 표면(100)의 외피(110) 및 내피(130)는 인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어질 수 있다. 다만, 상기의 소재로 한정되는 것은 아니다.The outer shell 110 and the inner shell 130 of the catheter surface 100 may be made of polyethylene, polypropylene which is a thermoplastic resin harmless to the human body. However, the present invention is not limited to the above materials.
도 7은 본 발명의 다른 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터에서 위치에 따른 카테터의 단면을 도시한 도면이다. 도 7에 도시된 바와 같이, 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터(10)는, 광통로(200)와 와이어통로(300)를 구별하는 역할을 하는 분리막(400)을 더 포함하여 구성될 수 있다. 또한, 실시예에 따라서 광통로(200)는 와이어통로(300)에 비해 그 단면적이 넓을 수 있다.7 is a view showing a cross section of the catheter according to the position in the optical coherence brain catheter for cerebrovascular surgery according to another embodiment of the present invention. As shown in FIG. 7, the optically coherent brain catheter 10 for cerebrovascular surgery according to an embodiment of the present invention is a separator that serves to distinguish between the optical path 200 and the wire path 300. 400 may be configured to further include. In addition, according to the embodiment, the optical path 200 may have a wider cross-sectional area than the wire path 300.
도 8은 본 발명의 또 다른 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터에서 내피 일체형 분리막을 도시한 도면이다. 도 8에 도시된 바와 같이 분리막(400)은 카테터 도관 표면(100)의 내피(130)와 결합하여 내피 일체형 분리막(410)을 이룰 수 있다. 또한, 분리막(400)의 재질은 인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어질 수 있으나 이에 한정되는 것은 아니다.8 is a diagram illustrating an endothelial integrated membrane in an optical coherence brain catheter for cerebrovascular surgery according to another embodiment of the present invention. As shown in FIG. 8, the separator 400 may be combined with the endothelial 130 of the catheter conduit surface 100 to form an endothelial integral membrane 410. In addition, the material of the separator 400 may be made of polyethylene, polypropylene, which is harmless to the human body, but is not limited thereto.
이중구멍으로 카테터를 구성함으로써, 마이크로 와이어와 광원을 서로 다른 방향으로 나오게 만들 수 있다. 이러한 경우, 마이크로 와이어가 카테터의 끝부분에서 옆쪽으로 짧게 나오는 것이 아니라, 멀리 떨어진 옆으로 나오게 만들 수 있다. 마이크로 와이어를 다른 방향으로 나오도록 하면, 마이크로 와이어와 별도의 위치로 광원의 삽입이 가능해지며, 유도와이어가 삽입되는 위치까지 광원의 삽입이 이루어질 필요가 없게 된다. 이에 따라, 카테터 전체가 일체로서 혈관내에 삽입 되는 것이 아닌, 필요에 따라서 카테터의 삽입 정도와 별도로 광원을 원하는 부위에 한하여 삽입함으로서 보다 접근성있고 편리한 시술이 가능하도록 한다.By constructing the catheter with a double hole, the microwire and the light source can be made to come out in different directions. In this case, the microwires can be made to come out to the far side, rather than short to the side at the end of the catheter. When the micro wires come out in different directions, the light source can be inserted into a position separate from the micro wires, and the light source does not need to be inserted until the induction wire is inserted. Accordingly, the entire catheter is not integrally inserted into the blood vessel, and the light source is inserted only at a desired portion separately from the degree of catheter insertion as needed, thereby enabling more accessible and convenient procedures.
도 9는 뇌혈관내 수술을 위한 광간섭성 브레인 카테터를 이용하는 모습을 도시한 도면이다. 도 9의 (a)는 기존의 OCT카테터를 이용하여 시술하는 모습을 도식화한 도면이다. 도 9의 (a)에 도시된 바에 따르면, 기존의 카테터는 OCT 렌즈(광원) 앞에 20㎜의 돌출된 부위를 포함하고 있어, 렌즈가 병변부위를 조사하기 위하여 카테터가 혈관내에서 병변부위를 지나 20㎜만큼 더 삽입되어야 한다.FIG. 9 is a diagram illustrating the use of an optical coherent brain catheter for cerebrovascular surgery. 9 (a) is a diagram illustrating a state of surgery using an existing OCT catheter. As shown in FIG. 9 (a), the conventional catheter includes a 20 mm protruding portion in front of the OCT lens (light source), so that the catheter passes through the lesion site in the blood vessel to irradiate the lesion site. It shall be inserted further by 20 mm.
도 9의 (b)는 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터를 이용하여 시술하는 모습을 도식화한 도면이다. 도 9의 (b)에 도시된 바에 따르면, 마이크로 와이어와 광원(OCT 렌즈)을 다른 방향으로 나오게 할 수 있는바, 광원과 카테터 끝 부분이 동일한 평면에 있도록 할 수 있다. 이에 따라, 기존의 카테터와 달리 필요한 시술, 병변부위 조사를 위하여 기존의 카테터와 달리 20㎜를 덜 삽입해도 되므로 접근성을 높일 수 있다.Figure 9 (b) is a diagram illustrating the operation using an optical coherence brain catheter for intravascular cerebrovascular surgery according to an embodiment of the present invention. As shown in (b) of FIG. 9, the micro wires and the light source (OCT lens) may be emitted in different directions, so that the light source and the catheter tip may be in the same plane. Accordingly, unlike the conventional catheter, it is possible to insert less 20mm unlike the conventional catheter for the procedure, the lesion site required to increase the accessibility.
또한, 기존의 심혈관 시술용 OCT카테터의 경우, 원위부가 50㎜로 긴 것이 통상적이다. 굴곡이 심하고, 깊이가 심혈관과는 다른 뇌혈관 시술을 위해서는 원위부의 길이가 50㎜로 길 필요가 없으며, 길이는 20㎜에서 30㎜ 정도로 짧은 것이 적절하다. 이에 따라, 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터(10)는, 카테터의 원위부 길이를 짧게 하여, 뇌혈관에 적절하게 적용하도록 한다.In addition, in the conventional OCT catheter for cardiovascular treatment, it is common that the distal portion is 50 mm long. For cerebrovascular procedures that are severely curved and deeper than cardiovascular vessels, the distal portion does not need to be 50 mm long, and preferably 20 mm to 30 mm short. Accordingly, the optical coherence brain catheter 10 for intravascular cerebrovascular surgery according to an embodiment of the present invention is to shorten the distal length of the catheter, to be appropriately applied to the cerebrovascular.
본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터(10)는, 와이어통로(300)의 끝부분에 카테터 세척을 위한 세척부를 더 포함할 수 있다. 카테터가 단일 구멍으로 이루어진 경우, 카테터의 세척을 위하여 광원, 광케이블 부분까지 전부 세척을 해야 하지만, 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터(10)와 같이 카테터를 이중구멍으로 구성한 경우, 마이크로 와이어(유도 와이어)가 통과하는 와이어통로(300) 부분에만 세척부를 포함시킴으로써, 보다 편리한 카테터의 세척이 가능하다.The optical coherent brain catheter 10 for cerebrovascular surgery according to an embodiment of the present invention may further include a washing unit for catheter cleaning at the end of the wire passage 300. If the catheter is made of a single hole, all of the light source, the optical cable portion should be washed to clean the catheter, but the catheter is the same as the optical coherent brain catheter 10 for intravascular cerebrovascular surgery according to an embodiment of the present invention. In the case of a double hole, the washing part is included only in the portion of the wire passage 300 through which the micro wires (induction wires) pass, whereby the catheter can be washed more conveniently.
앞서 기술한 세척부는, 카테터 내부로 식염수를 흘림(Saline Flushing)으로써, 카테터를 세척할 수 있다.The washing unit described above may clean the catheter by saline flushing into the catheter.
도 10은 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법의 흐름도를 도시한 도면이다. 도 10에 도시된 바와 같이, 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법은, 카테터 도관을 구성하는 표면(100), 표면(100)에 둘러싸여 광원과 광케이블이 지나가는 통로로서 작용하는 광통로(200), 및 광통로와 별개의 통로로서, 표면(100)에 둘러싸여 와이어가 지나가는 통로로서 작용하는 와이어통로(300)를 포함하는 카테터를 이용하는 방법으로서, 광통로(200)와 와이어통로(300)를 포함하는 카테터가, 혈관에 삽입되는 단계(S100), 및 단계 S100에서 삽입된 카테터의 광통로(200)에 광원 및 광케이블을 통과시킴으로써 광간섭성 단층촬영을 수행하는 단계를 포함한다.10 is a flowchart illustrating a method of using an optical coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention. As shown in FIG. 10, a method of using an optical coherent brain catheter for cerebrovascular surgery according to an embodiment of the present invention includes a light source surrounded by a surface 100 and a surface 100 constituting a catheter conduit. A method of using a catheter comprising an optical path 200 acting as a passage through which an optical cable passes, and a wire path 300 acting as a passage through which the wire is surrounded by the surface 100 as a path separate from the optical path, The catheter including the passage 200 and the wire passage 300 is inserted into the blood vessel (S100), and the optical coherence tomography by passing the light source and the optical cable through the optical passage 200 of the catheter inserted in step S100 It includes the step of performing.
각각의 단계들과 관련된 상세한 내용들은, 앞서 본 발명의 일실시예에 따른 뇌혈관내 수술을 위한 광간섭성 브레인 카테터(10)와 관련하여 충분히 설명되었으므로, 상세한 설명은 생략하기로 한다.Details related to each step have been described above in connection with the optical coherent brain catheter 10 for the intravascular cerebrovascular surgery according to an embodiment of the present invention, a detailed description thereof will be omitted.
상술한 바와 같이, 본 발명에서 제안하고 있는 뇌혈관내 수술을 위한 광간섭성 브레인 카테터 및 그 이용방법에 따르면, 카테터의 샤프트 튜브가 광통로와 와이어통로의 이중구멍으로 구성되도록 하여, 마이크로 와이어가 광케이블과 다른 방향으로 나올 수 있도록 함으로써, 카테터를 혈관에 덜 삽입해도 필요한 시술이 가능하도록 할 수 있다. 또한, 본 발명에 따르면, 카테터의 표면이 꼬임 부분을 포함하여 구성되도록 함으로써, 접근성을 증가시키도록 할 수 있다. 뿐만 아니라, 본 발명에 따르면, 카테터의 원위부 길이를 짧게 함으로써, 뇌혈관에 적절하게 적용하도록 할 수 있다.As described above, according to the optical coherence brain catheter for the intravascular cerebrovascular surgery proposed by the present invention and a method of using the same, the microtube is formed so that the shaft tube of the catheter is composed of a double hole of an optical channel and a wire channel By allowing it to come out in a different direction from the optical cable, less catheter can be inserted into the blood vessel to allow the necessary procedures. In addition, according to the present invention, the surface of the catheter may be configured to include a twisted portion, thereby increasing accessibility. In addition, according to the present invention, by shortening the distal length of the catheter, it can be appropriately applied to cerebrovascular.
이상 설명한 본 발명은 본 발명이 속한 기술분야에서 통상의 지식을 가진 자에 의하여 다양한 변형이나 응용이 가능하며, 본 발명에 따른 기술적 사상의 범위는 아래의 특허청구범위에 의하여 정해져야 할 것이다.The present invention described above may be variously modified or applied by those skilled in the art, and the scope of the technical idea according to the present invention should be defined by the following claims.

Claims (20)

  1. 카테터의 샤프트 튜브를 구성하는 표면(100);A surface 100 constituting the shaft tube of the catheter;
    상기 표면(100)에 둘러싸여 광원과 광케이블이 지나가는 통로로서 작용하는 광통로(200); 및An optical path 200 surrounded by the surface 100 and serving as a passage through which a light source and an optical cable pass; And
    상기 광통로(200)와 별개의 통로로서, 상기 표면(100)에 둘러싸여 와이어가 지나가는 통로로서 작용하는 와이어통로(300)를 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.An optical coherent brain catheter for cerebrovascular surgery, characterized in that it comprises a wire passage 300 which is a separate passage from the light passage 200 and is surrounded by the surface 100 and serves as a passage through which the wire passes. .
  2. 제1항에 있어서, 상기 표면(100)은,The method of claim 1, wherein the surface 100,
    접근성을 확보하기 위한 꼬임 부분(120)을 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.An optically coherent brain catheter for cerebrovascular surgery, comprising a twisted portion 120 to ensure accessibility.
  3. 제2항에 있어서, 상기 꼬임 부분(120)은,The method of claim 2, wherein the twisted portion 120,
    스테인리스강 재질의 금속사가 꼬여서 이루어지는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.An optically coherent brain catheter for cerebrovascular surgery, characterized in that the metal yarn made of stainless steel twisted.
  4. 제1항에 있어서, 상기 표면(100)은,The method of claim 1, wherein the surface 100,
    카테터 도관의 바깥쪽 면을 이루는 외피(110); 및Envelope 110 constituting the outer side of the catheter conduit; And
    카테터 도관의 안쪽 면을 이루는 내피(130)를 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.An optically coherent brain catheter for cerebrovascular surgery, characterized in that it comprises an endothelial (130) forming an inner surface of the catheter conduit.
  5. 제4항에 있어서, 상기 외피(110) 및 내피(130)는,The method according to claim 4, wherein the outer shell 110 and the inner shell 130,
    인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어지는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.An optical coherent brain catheter for cerebrovascular surgery, characterized in that the thermoplastic resin is made of polyethylene, polypropylene, harmless to the human body.
  6. 제1항에 있어서,The method of claim 1,
    상기 광통로(200)는 상기 와이어통로(300)에 비해 그 단면적이 넓은 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.The optical path 200 is characterized in that the cross-sectional area is wider than the wire path 300, optical coherence brain catheter for cerebrovascular surgery.
  7. 제1항에 있어서,The method of claim 1,
    상기 광통로(200)와 상기 와이어통로(300)를 구별하는 역할을 하는 분리막(400)을 더 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.The optical coherence brain catheter for cerebrovascular surgery, characterized in that it further comprises a separator 400 which serves to distinguish between the optical path 200 and the wire path (300).
  8. 제7항에 있어서, 상기 분리막(400)은,The method of claim 7, wherein the separation membrane 400,
    상기 표면(100)의 내피(130)와 결합하여 내피 일체형 분리막(410)을 이루는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.Combined with the endothelial 130 of the surface 100 to form an endothelial integrated membrane 410, optical coherent brain catheter for cerebrovascular surgery.
  9. 제7항에 있어서, 상기 분리막(400)은,The method of claim 7, wherein the separation membrane 400,
    인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어지는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.An optical coherent brain catheter for cerebrovascular surgery, characterized in that the thermoplastic resin is made of polyethylene, polypropylene, harmless to the human body.
  10. 제1항에 있어서,The method of claim 1,
    상기 와이어통로(300)의 끝 부분에 카테터 세척을 위한 세척부를 더 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터.An optical coherence brain catheter for cerebrovascular surgery, characterized in that it further comprises a washing unit for catheter cleaning at the end of the wire passage (300).
  11. 카테터의 샤프트 튜브를 구성하는 표면(100); 상기 표면(100)에 둘러싸여 광원과 광케이블이 지나가는 통로로서 작용하는 광통로(200); 및 상기 광통로(200)와 별개의 통로로서, 상기 표면(100)에 둘러싸여 와이어가 지나가는 통로로서 작용하는 와이어통로(300)를 포함하는 카테터를 이용하는 방법으로서,A surface 100 constituting the shaft tube of the catheter; An optical path 200 surrounded by the surface 100 and serving as a passage through which a light source and an optical cable pass; And a wire passage 300 which is a separate passage from the optical passage 200 and is surrounded by the surface 100 and serves as a passage through which the wire passes.
    (1) 광통로(200)와 와이어통로(300)를 포함하는 카테터가 혈관에 삽입되는 단계; 및(1) a catheter including an optical path 200 and a wire path 300 is inserted into a blood vessel; And
    (2) 상기 단계 (1)에서 삽입된 카테터의 상기 광통로(200)에 광원 및 광케이블을 통과시킴으로써 광간섭성 단층촬영을 수행하는 단계를 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.(2) performing optical coherence tomography by passing a light source and an optical cable through the optical path 200 of the catheter inserted in the step (1), the optical for cerebrovascular surgery Method of Using Coherent Brain Catheter.
  12. 제11항에 있어서, 상기 표면(100)은,The method of claim 11, wherein the surface 100,
    접근성을 확보하기 위한 꼬임 부분(120)을 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.Method for using an optical coherence brain catheter for intravascular cerebrovascular surgery, characterized in that it comprises a twisted portion (120) to ensure accessibility.
  13. 제12항에 있어서, 상기 꼬임 부분(120)은,The method of claim 12, wherein the twisted portion 120,
    스테인리스강 재질의 금속사가 꼬여서 이루어지는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.A method of using an optical coherent brain catheter for cerebrovascular surgery, characterized in that the metal yarn made of stainless steel twisted.
  14. 제11항에 있어서, 상기 표면(100)은,The method of claim 11, wherein the surface 100,
    카테터 도관의 바깥쪽 면을 이루는 외피(110); 및Envelope 110 constituting the outer side of the catheter conduit; And
    카테터 도관의 안쪽 면을 이루는 내피(130)를 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.A method of using an optical coherent brain catheter for cerebrovascular surgery, comprising an endothelial (130) forming an inner surface of the catheter conduit.
  15. 제14항에 있어서, 상기 외피(110) 및 내피(130)는,The method according to claim 14, wherein the outer shell 110 and the inner shell 130,
    인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어지는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.A method of using an optical coherent brain catheter for cerebrovascular surgery, characterized in that the thermoplastic resin is made of polyethylene, polypropylene, harmless to the human body.
  16. 제11항에 있어서,The method of claim 11,
    상기 광통로(200)는 상기 와이어통로(300)에 비해 그 단면적이 넓은 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.The optical path 200 is characterized in that its cross-sectional area is wider than the wire path 300, the method of using an optical coherence brain catheter for cerebrovascular surgery.
  17. 제11항에 있어서,The method of claim 11,
    상기 광통로(200)와 상기 와이어통로(300)를 구별하는 역할을 하는 분리막(400)을 더 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.Method for using an optical coherent brain catheter for cerebrovascular surgery, characterized in that it further comprises a separation membrane (400) which serves to distinguish between the optical path 200 and the wire path (300).
  18. 제17항에 있어서, 상기 분리막(400)은,The method of claim 17, wherein the separator 400,
    상기 표면(100)의 내피(130)와 결합하여 내피 일체형 분리막(410)을 이루는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.Method of using an optical coherent brain catheter for cerebrovascular surgery, characterized in that to form an endothelial integral membrane 410 in combination with the endothelial 130 of the surface (100).
  19. 제17항에 있어서, 상기 분리막(400)은,The method of claim 17, wherein the separator 400,
    인체에 무해한 열가소성 수지인 폴리에틸렌, 폴리프로필렌으로 이루어지는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.A method of using an optical coherent brain catheter for cerebrovascular surgery, characterized in that the thermoplastic resin is made of polyethylene, polypropylene, harmless to the human body.
  20. 제11항에 있어서,The method of claim 11,
    상기 와이어통로(300)의 끝 부분에 카테터 세척을 위한 세척부를 더 포함하는 것을 특징으로 하는, 뇌혈관내 수술을 위한 광간섭성 브레인 카테터의 이용방법.Method for using an optical coherent brain catheter for cerebrovascular surgery, characterized in that it further comprises a washing unit for catheter cleaning at the end of the wire passage (300).
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