WO2019112750A3 - Appareil et procédés de microactuationnement fluidique d'électrodes - Google Patents

Appareil et procédés de microactuationnement fluidique d'électrodes Download PDF

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Publication number
WO2019112750A3
WO2019112750A3 PCT/US2018/059881 US2018059881W WO2019112750A3 WO 2019112750 A3 WO2019112750 A3 WO 2019112750A3 US 2018059881 W US2018059881 W US 2018059881W WO 2019112750 A3 WO2019112750 A3 WO 2019112750A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrodes
methods
microactuation
fluidic
longevity
Prior art date
Application number
PCT/US2018/059881
Other languages
English (en)
Other versions
WO2019112750A2 (fr
WO2019112750A9 (fr
Inventor
Jacob T. Robinson
Caleb T. Kemere
Matteo Pasquali
Flavia VITALE
Daniel Vercosa
Original Assignee
William Marsh Rice University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William Marsh Rice University filed Critical William Marsh Rice University
Publication of WO2019112750A2 publication Critical patent/WO2019112750A2/fr
Publication of WO2019112750A9 publication Critical patent/WO2019112750A9/fr
Publication of WO2019112750A3 publication Critical patent/WO2019112750A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37205—Microstimulators, e.g. implantable through a cannula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
    • A61B5/293—Invasive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/686—Permanently implanted devices, e.g. pacemakers, other stimulators, biochips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
    • A61B2562/0215—Silver or silver chloride containing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A61B5/377—Electroencephalography [EEG] using evoked responses
    • A61B5/378—Visual stimuli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electrotherapy Devices (AREA)

Abstract

L'invention concerne un nouvel appareil, des systèmes et procédés utilisant une technologie de microactionnement fluidique qui permet l'insertion et le positionnement d'électrodes flexibles, sans nécessité de support de raidissement. Selon certains modes de réalisation, la présente invention permet une nette réduction du traumatisme subi par les tissus mous du cerveau pendant l'implantation et une amélioration de la biocompatibilité, la longévité et l'efficacité thérapeutique de l'électrode neuronale.
PCT/US2018/059881 2017-11-09 2018-11-08 Appareil et procédés de microactuationnement fluidique d'électrodes WO2019112750A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762583787P 2017-11-09 2017-11-09
US62/583,787 2017-11-09

Publications (3)

Publication Number Publication Date
WO2019112750A2 WO2019112750A2 (fr) 2019-06-13
WO2019112750A9 WO2019112750A9 (fr) 2019-08-22
WO2019112750A3 true WO2019112750A3 (fr) 2019-10-31

Family

ID=66749935

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2018/059881 WO2019112750A2 (fr) 2017-11-09 2018-11-08 Appareil et procédés de microactuationnement fluidique d'électrodes

Country Status (1)

Country Link
WO (1) WO2019112750A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112869747B (zh) * 2019-11-29 2022-11-25 清华大学 微电极及其制作和使用方法、塞类装置和微电极系统
WO2022109186A1 (fr) * 2020-11-18 2022-05-27 University Of Florida Research Foundation, Incorporated Optrode microfluidique multifonctions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040026007A1 (en) * 2002-02-14 2004-02-12 Brian Hubert Method and apparatus for direct fabrication of nanostructures
US20050107716A1 (en) * 2003-11-14 2005-05-19 Media Lab Europe Methods and apparatus for positioning and retrieving information from a plurality of brain activity sensors
WO2012139124A1 (fr) * 2011-04-07 2012-10-11 Georgia Tech Research Corporation Réseau d'électrodes à microcanaux régénératifs pour interfaçage neuronal périphérique

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040026007A1 (en) * 2002-02-14 2004-02-12 Brian Hubert Method and apparatus for direct fabrication of nanostructures
US20050107716A1 (en) * 2003-11-14 2005-05-19 Media Lab Europe Methods and apparatus for positioning and retrieving information from a plurality of brain activity sensors
WO2012139124A1 (fr) * 2011-04-07 2012-10-11 Georgia Tech Research Corporation Réseau d'électrodes à microcanaux régénératifs pour interfaçage neuronal périphérique

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
VITALE ET AL.: "Fluidic microactuation of flexible electrodes for neural recording", BIORXIV , THE REPRINT SERVER FOR BIOLOGY, NEUROSCIENCE, 26 June 2017 (2017-06-26), pages 1 - 29, XP055648113 *
VITALE ET AL.: "Fluidic microactuation of flexible electrodes for neural recording", NANO LETTERS, vol. 18, 8 December 2017 (2017-12-08) - 10 January 2018 (2018-01-10), pages 326 - 325, XP055648119 *

Also Published As

Publication number Publication date
WO2019112750A2 (fr) 2019-06-13
WO2019112750A9 (fr) 2019-08-22

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