WO2019090125A3 - Système d'administration de médicament transdermique anti-abus intelligent - Google Patents

Système d'administration de médicament transdermique anti-abus intelligent Download PDF

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Publication number
WO2019090125A3
WO2019090125A3 PCT/US2018/059026 US2018059026W WO2019090125A3 WO 2019090125 A3 WO2019090125 A3 WO 2019090125A3 US 2018059026 W US2018059026 W US 2018059026W WO 2019090125 A3 WO2019090125 A3 WO 2019090125A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug delivery
transdermal drug
abuse
smart
delivery system
Prior art date
Application number
PCT/US2018/059026
Other languages
English (en)
Other versions
WO2019090125A2 (fr
Inventor
Navdeep KAUR
Anubhav Arora
Aofie MULLIGAN
Kevin GELSTON
Original Assignee
Chrono Therapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chrono Therapeutics Inc. filed Critical Chrono Therapeutics Inc.
Publication of WO2019090125A2 publication Critical patent/WO2019090125A2/fr
Publication of WO2019090125A3 publication Critical patent/WO2019090125A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un dispositif d'administration de médicament transdermique comprend un réservoir, une membrane d'administration de médicament transdermique, et un trajet de fluide entre le réservoir et la membrane d'administration de médicament transdermique. Le réservoir comprend une formulation de gel ayant un agoniste opioïde. La membrane d'administration de médicament transdermique est conçue pour entrer en contact avec la peau d'un patient afin de délivrer l'agoniste opioïde sur la peau.
PCT/US2018/059026 2017-11-02 2018-11-02 Système d'administration de médicament transdermique anti-abus intelligent WO2019090125A2 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201762580895P 2017-11-02 2017-11-02
US201762580884P 2017-11-02 2017-11-02
US62/580,895 2017-11-02
US62/580,884 2017-11-02
US201862616340P 2018-01-11 2018-01-11
US62/616,340 2018-01-11
US201862732952P 2018-09-18 2018-09-18
US62/732,952 2018-09-18

Publications (2)

Publication Number Publication Date
WO2019090125A2 WO2019090125A2 (fr) 2019-05-09
WO2019090125A3 true WO2019090125A3 (fr) 2020-04-02

Family

ID=66331474

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2018/059026 WO2019090125A2 (fr) 2017-11-02 2018-11-02 Système d'administration de médicament transdermique anti-abus intelligent

Country Status (1)

Country Link
WO (1) WO2019090125A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 経皮薬剤送達の装置及び方法
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005081825A2 (fr) * 2004-02-23 2005-09-09 Euro-Celtique S.A. Dispositif de distribution transdermique d'opioides empechant une utilisation abusive et contenant des microspheres d'antagonistes d'opioides
WO2007041544A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Systemes d'administration transdermique de medicament, dispositifs, et methodes faisant intervenir un agoniste opioide et/ou un antagoniste opioide
US8481560B2 (en) * 2010-04-02 2013-07-09 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
US20160220798A1 (en) * 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
WO2005081825A2 (fr) * 2004-02-23 2005-09-09 Euro-Celtique S.A. Dispositif de distribution transdermique d'opioides empechant une utilisation abusive et contenant des microspheres d'antagonistes d'opioides
WO2007041544A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Systemes d'administration transdermique de medicament, dispositifs, et methodes faisant intervenir un agoniste opioide et/ou un antagoniste opioide
US8481560B2 (en) * 2010-04-02 2013-07-09 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
US20160220798A1 (en) * 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems

Also Published As

Publication number Publication date
WO2019090125A2 (fr) 2019-05-09

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