WO2019087158A3 - Formulation comprising oxazolidin-2-one-pyrimidine derivative - Google Patents
Formulation comprising oxazolidin-2-one-pyrimidine derivative Download PDFInfo
- Publication number
- WO2019087158A3 WO2019087158A3 PCT/IB2018/058677 IB2018058677W WO2019087158A3 WO 2019087158 A3 WO2019087158 A3 WO 2019087158A3 IB 2018058677 W IB2018058677 W IB 2018058677W WO 2019087158 A3 WO2019087158 A3 WO 2019087158A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- oxazolidin
- formulation
- pyrimidine derivative
- compositions
- formula
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to novel topical pharmaceutical compositions comprising an oxazolidin-2-one-pyrimidine compound of formula (I), a method of manufacturing such compositions, as well as uses of such compositions. The present invention also relates to a novel crystalline form of the compound of formula (I).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201711039501 | 2017-11-06 | ||
IN201711039501 | 2017-11-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2019087158A2 WO2019087158A2 (en) | 2019-05-09 |
WO2019087158A3 true WO2019087158A3 (en) | 2019-06-20 |
Family
ID=64316605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2018/058677 WO2019087158A2 (en) | 2017-11-06 | 2018-11-05 | Formulation comprising oxazolidin-2-one-pyrimidine derivative |
Country Status (2)
Country | Link |
---|---|
TW (1) | TW201929861A (en) |
WO (1) | WO2019087158A2 (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014072956A1 (en) * | 2012-11-12 | 2014-05-15 | Novartis Ag | Oxazolidin-2-one-pyrimidine derivatives |
-
2018
- 2018-11-02 TW TW107138926A patent/TW201929861A/en unknown
- 2018-11-05 WO PCT/IB2018/058677 patent/WO2019087158A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014072956A1 (en) * | 2012-11-12 | 2014-05-15 | Novartis Ag | Oxazolidin-2-one-pyrimidine derivatives |
Non-Patent Citations (4)
Title |
---|
"butylparaben, methylparaben, propylparaben ED - Rowe Raymond C", 31 December 2006, HANDBOOK OF PHARMACEUTICAL EXCIPIENTS, PHARMACEUTICAL PRESS, LONDON, PAGE(S) 83 - 85,466, ISBN: 0-85369-618-7, XP002706362 * |
"Handbook of Pharmaceutical Excipients, 3rd edition", 2000, AMERICAN PHARMACEUTICAL ASSOCIATION, Washington, D.C., article P J WELLER: "Phenoxyethanol", pages: 370 - 371, XP055546212 * |
"Handbook of Pharmaceutical Excipients, 3rd edition", 2000, AMERICAN PHARMACEUTICAL ASSOCIATION, Washington, D.C., article P J WELLER: "Phenylethyl Alcohol", pages: 372 - 373, XP055546213 * |
KIBBE A H: "BENZYL ALCOHOL", 2000, HANDBOOK OF PHARMACEUTICAL EXCIPIENTS, ED.3, AMERICAN PHARMACEUTICAL ASSOCIATION ET AL, USA, PAGE(S) 41,191 - 220,,372,442, XP002533446 * |
Also Published As
Publication number | Publication date |
---|---|
TW201929861A (en) | 2019-08-01 |
WO2019087158A2 (en) | 2019-05-09 |
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