WO2019061819A1 - Endoscope system and light source apparatus - Google Patents

Endoscope system and light source apparatus Download PDF

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Publication number
WO2019061819A1
WO2019061819A1 PCT/CN2017/114749 CN2017114749W WO2019061819A1 WO 2019061819 A1 WO2019061819 A1 WO 2019061819A1 CN 2017114749 W CN2017114749 W CN 2017114749W WO 2019061819 A1 WO2019061819 A1 WO 2019061819A1
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WO
WIPO (PCT)
Prior art keywords
light
tissue
organ
image
light source
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PCT/CN2017/114749
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French (fr)
Chinese (zh)
Inventor
郭祖强
杨炳柯
李屹
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深圳市绎立锐光科技开发有限公司
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Publication of WO2019061819A1 publication Critical patent/WO2019061819A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/042Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by a proximal camera, e.g. a CCD camera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/044Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for absorption imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/00071Insertion part of the endoscope body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/00071Insertion part of the endoscope body
    • A61B1/0008Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00096Optical elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0655Control therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter

Definitions

  • the invention relates to the field of medical optical technology, in particular to an endoscope system and a light source device.
  • an endoscope system including an endoscope, a light source device, a processor, a display, and the like is generally used to observe the surface layer and the medium-deep tissue of the living tissue.
  • the endoscope system performs internal observation of the specimen, when observing the tissue at different depths, it is necessary to illuminate the tissue of the observation depth with light of a specific wavelength band, and the image of the observed portion can be accurately focused before the observed tissue can be clearly imaged. .
  • the light source is usually a xenon lamp, a light emitting diode (LED), and a laser disc (LD) plus a laser powder to generate white light for illumination. Since the light absorption rate of the organ or tissue to be examined is different for different wavelengths, the spectral composition of the light reflected by the tissue is largely different from the illumination light. If white light is used for illumination, the image of the reflected light generated by the charge coupled device image sensor (CCD) is used to display the image tones, which is unfavorable for the user to observe and Judge.
  • the endoscopic system adopts an image processing method to enlarge/reduce the intensity of the optical signal collected by the CCD, thereby obtaining an image suitable for observation. Although this processing method is relatively simple, its accuracy is low due to the influence of noise in the collected signal. When the optical signal intensity is amplified by image processing, the noise intensity is also amplified, and when the signal intensity is reduced, the light energy is lost in vain.
  • the imaging elements of the endoscope system generally use a color or black-and-white CCD to record the light intensity and distribution of the imaging surface. But the depth of field of this camera element There is a contradiction in the aperture that is difficult to tune. To obtain a large depth of field, it is necessary to reduce the aperture. At this time, the signal-to-noise ratio is reduced, and noise is generated.
  • the large aperture causes the depth of field to be small, and the imaging surface needs to be accurately focused while the background is blurred.
  • the present invention also necessitates a light source device for improving the utilization of a light source, which is capable of matching light sources of different primary color light components according to different light absorption rates of an organ or tissue to be examined.
  • the invention provides an endoscope system comprising:
  • An endoscope insertion portion for insertion into an organ or tissue to be examined
  • a light source device comprising a light source that emits excitation light, which is excited by the excitation light to generate a laser-converted wavelength conversion device, the excitation light and the laser-receiving light forming illumination light and being guided by the endoscope insertion portion
  • a light source device comprising a light source that emits excitation light, which is excited by the excitation light to generate a laser-converted wavelength conversion device, the excitation light and the laser-receiving light forming illumination light and being guided by the endoscope insertion portion
  • the processor includes a photographing component, wherein the photographing component is a light field camera, and the light field camera photographs an observation portion of an organ or tissue to be examined illuminated by illumination light from the light source device, and receives different optical signals in time series And converted to a video signal; and
  • a display unit configured to receive a video signal transmitted by the processor and display an image of the observed portion.
  • the endoscope system further includes a filter device for filtering the laser light generated by the wavelength conversion device, wherein the proportion of light of different colors in the illumination light is adjusted The light intensity of the light source and/or adjustment of the wavelength conversion device and/or adjustment of the filter device are achieved.
  • the light source device further includes a light source control portion that adjusts a current magnitude of the light source at different periods in the same pulse interval to adjust the light intensity of the light source.
  • the wavelength conversion device comprises a plurality of regions carrying or not carrying a wavelength converting material or carrying different wavelength converting materials, the wavelength converting device further comprising an adjusting mechanism, the adjusting mechanism adjusting The area ratio of the regions is adjusted to adjust the proportion of light of different colors in the illumination light.
  • the filter device includes a plurality of filter zones and an adjustment mechanism, the adjustment mechanism adjusting an area ratio of the filter zones to adjust a ratio of light of different colors in the illumination light.
  • the light field camera comprises a black and white charge coupled device chip for recording optical signals of different depths of field of the organ or tissue to be examined.
  • the processor includes a red image conversion unit, a green image conversion unit, and a blue image conversion unit
  • the red image conversion unit is configured to process a red signal of each frame image, and corresponding
  • the red signal is converted into a first surface layer, a first middle layer, and a first deep layer signal of the organ or tissue to be inspected
  • the green image conversion unit is configured to process the green signal of each frame image, and the corresponding green signal Converting to a second skin layer, a second middle layer, and a second deep layer signal of the organ or tissue to be examined
  • the blue image converting portion is configured to process a blue signal of each frame image, and corresponding blue
  • the signal is converted to a third surface layer, a third middle layer, and a third deep layer signal of the organ or tissue to be examined.
  • the processor further includes an image combining unit, where the image combining unit is configured to combine the first surface layer signal, the second surface layer signal, and the third surface layer signal to obtain a Determining a surface image signal of the organ or tissue to be examined; combining the first intermediate layer signal, the second intermediate layer signal, and the third intermediate layer signal to obtain a middle layer image signal of the organ or tissue to be examined; Combining the first deep layer signal, the second deep layer signal and the third deep layer signal to obtain a deep image signal of the organ or tissue to be examined.
  • the display portion includes a first display area for displaying a surface layer image of the organ or tissue to be examined, a second display area for displaying a middle layer image of the object or tissue to be examined, and And displaying a third display area of the deep image of the organ or tissue to be examined.
  • the present invention also provides a light source device including a light source that emits excitation light, and a wavelength conversion device that generates laser light by excitation of the excitation light, the excitation light and the excitation
  • the light forms illumination light, and the proportion of light of different colors in the illumination light is adjustable.
  • the endoscope system of the present invention provides a light source device capable of adjusting the proportion of illumination light and an observation portion of an organ or tissue to be examined that can illuminate the emitted light from the light source device.
  • the endoscope system of the present invention employs a light field camera as a photographing element, which can not only provide a clear image of an observation portion of an organ or tissue to be examined, but also an image capable of displaying a true color, thereby facilitating the user's internal organization of the specimen. Observe and diagnose.
  • the endoscope system of the present invention is capable of clearly imaging the different depths of tissue observed.
  • the present invention also provides a light source device capable of matching light sources of different primary color light components according to different light absorption rates of an organ or tissue to be examined, so that the imaging portion of the endoscope system can clearly image the observed tissue. .
  • FIG. 1 is a skeleton view of an endoscope system according to a first embodiment of the present invention.
  • FIG. 2 is a schematic view showing the proportion of the angle of the light segments of each color in the filter device.
  • Fig. 3 is a graph showing the absorption coefficient of an organ or tissue to be examined for illumination light of different wavelengths.
  • Fig. 4 is a schematic view showing the spectrum of absorbed light, illumination light, and reflected light of different wavelengths of the organ or tissue to be examined.
  • Fig. 5 is a schematic view showing a photographing operation of a light field camera.
  • Fig. 6 is a skeleton diagram of an endoscope system according to a first embodiment of the present invention.
  • Fig. 7 is a schematic view of a display unit.
  • Endoscope system 100 Light source device 10
  • Light source control unit 11 light source 12
  • Wavelength conversion device 13 Filter device 14 Filter 140 Red light filter unit 141 Green filter unit 142 Blue light filter section 143 Endoscope insertion 20 Astigmatism twenty one Lens group twenty two processor 30
  • Shooting component 31 Shooting controller 32
  • Image processor 33 Blu-ray image conversion unit 331 Green light image conversion unit 332 Red light image conversion unit 333 Image combination department 334 Second control unit 34
  • Storage department 35 First control department 40
  • Display department 50 First display area 51
  • Second display area 52 Third display area 53
  • the endoscope system 100 includes a light source device 10, an endoscope insertion portion 20, a processor 30, a first control portion 40, and a display portion 50.
  • the light source device 10 is configured to generate illumination light and transmit it to the endoscope insertion portion 20 to illuminate an organ or tissue to be examined
  • the photographing device 30 is configured to photograph and process the organ or tissue to be examined.
  • the captured image is used to set or adjust different modes of the light source device 10 to perform different organs or tissues.
  • the display unit 50 is configured to display image information transmitted by the processor 30.
  • the light source device 10 is disposed at a front end of the endoscope insertion portion 20, and the processor 30 is disposed at a rear end of the endoscope insertion portion 20. It can be understood that in other embodiments, the light source device 10 and the processor 30 may be disposed on the same side of the endoscope insertion portion 20.
  • the first control unit 40 and the display unit 50 are electrically connected to the processor 30.
  • the light source device 10 is for supplying illumination light that illuminates an observation portion of the organ or tissue to be examined.
  • the light source device 10 includes a light source control unit 11, a light source 12, a wavelength conversion device 13, and a filter device 14.
  • the light source control unit 11 can drive and control the light source 12.
  • the light source 12 is capable of emitting excitation light, and the wavelength conversion device 13 emits a laser beam by excitation of the excitation light, and the excitation light and the laser light source together constitute illumination light for illuminating the organ or tissue to be examined. .
  • a plurality of regions may be disposed on the wavelength conversion device 13, and the plurality of regions respectively carry or do not carry a wavelength conversion material or carry different wavelength conversion materials, so that the excitation light emitted by the light source 12 is irradiated
  • the wavelength conversion device 13 is capable of generating a laser beam of a specific spectrum.
  • the wavelength converting material is, for example, but not limited to, a phosphor, a quantum dot or a dye.
  • the laser light may be a blue, green or yellow laser or the like depending on the material properties of the wavelength converting material.
  • the organ or tissue to be examined is, for example, but not limited to, an ear, a nose, a throat, a rectum, a bladder tissue, a joint, a mucosa tissue, a blood vessel, a venous blood vessel, and an arterial blood vessel.
  • the light source control unit 11 can control the start, end, drive time, synchronization timing, and the like of the respective portions of the light source device 10.
  • the light source 12 is a laser light source, specifically a blue laser diode.
  • the light source 12 is capable of emitting blue excitation light.
  • the excitation light is a blue laser having a center wavelength of 445 nanometers (nm).
  • the blue laser light emitted by the light source 12 can be conducted to the wavelength conversion device 13 through an optical fiber.
  • the wavelength conversion device 13 has a yellow phosphor thereon, so the blue laser light emitted by the light source 12 excites the After the wavelength conversion device 13 generates a yellow laser light, the blue excitation light and the yellow laser light are mixed to generate white light for illumination, and the illumination light is guided to the object through the endoscope insertion portion 20.
  • the organ or tissue is examined to facilitate observation by the observer of the organ or tissue to be examined.
  • the filter device 14 is disposed behind the wavelength conversion device 13 for filtering the illumination light to make the illumination light color more pure.
  • the filter device 14 includes a filter 140.
  • the filter 140 has a circular plate shape and is divided into a plurality of portions in the circumferential direction, and each portion of the filter 140 is capable of transmitting light of a specific wavelength range.
  • the filter 140 includes a plurality of filter regions for passing light of a specific wavelength range.
  • the filter region can be a red filter region, a blue filter region, a green filter region, a yellow filter region, etc., which can be set as needed. Therefore, since the filter device 14 is continuously rotated, when the white light passes through the filter 140 of the filter device 14, time-series light of a specific color can be generated at a time.
  • Figure 3 shows the absorption coefficient curve of the organ or tissue to be examined for illumination light of different wavelengths. As shown in FIG. 3, the organ or tissue to be examined has different absorption rates for light of respective colors (or wavelengths).
  • the absorption coefficient of the blue light is higher in the organ or tissue to be examined, and the light intensity of the blue light reflected by the organ or tissue to be examined is lower than that of the blue light.
  • the blue light is lost during the irradiation and reflection;
  • the absorption coefficient of the red light is low in the organ or tissue to be examined, and the light intensity of the red light reflected through the organ or tissue to be examined is relatively illuminating the red light.
  • the light intensity is high, and the red light is less likely to be lost during illumination and reflection. Therefore, in order to cause the illumination light to illuminate the organ or tissue to be examined, a real image can be displayed.
  • the light absorption coefficient of the organ or tissue to be examined adjusts the proportion of light of different colors in the illumination light.
  • the absorption rate of light of different wavelengths is also different from that of normal tissues.
  • the woven, diseased tissue and normal tissue can illuminate the organ or tissue to be examined with illumination light of different spectral components according to the difference in their absorption coefficients.
  • the absorption coefficients of different wavelengths of illumination light are different for different organs or tissues, so when determining the primary color light component of the emitted light, firstly, different organs or tissues are tested for absorption (or reflection) of different wavelengths. The spectral curve, and then the proportion of light of different colors in the emitted light is adjusted according to the absorption (or reflection) of the organ or tissue.
  • the light source device 10 can adjust the intensity of the different colors of the illumination light by adjusting the intensity of the excitation light of the light source 12 for different periods in the same pulse period by the light source control unit 11.
  • the excitation light emitted by the light source 12 at different periods in the same pulse period illuminates different regions of the wavelength conversion device 13.
  • the wavelength converting material has a blue phosphor region and a green phosphor region
  • the light source 12 has an excitation light period corresponding to the yellow phosphor region and an excitation light period corresponding to the green region in the same pulse period. Therefore, when it is required to increase the proportion of blue light in the illumination light, the intensity of the excitation light in the excitation light period corresponding to the blue phosphor region may be increased, and the excitation light in the excitation light period corresponding to the green phosphor region may be increased.
  • the intensity is constant, so that the blue light generated by the excitation light after being irradiated to the blue phosphor region of the wavelength conversion device 13 is increased by the laser, and the green laser is kept unchanged, thereby increasing the proportion of blue light in the laser, thereby achieving The purpose of increasing the proportion of blue light in the illumination light is improved.
  • the blue light ratio of the illumination light can also be improved by keeping the excitation light intensity in the excitation light period of the blue light region corresponding to the light source 12 while reducing the intensity of the excitation light in the excitation light period corresponding to the green region of the light source 12; Or increasing the intensity of the excitation light in the excitation light period of the blue light region corresponding to the light source 12 while reducing the green area corresponding to the light source 12
  • the manner in which the intensity of the excitation light is excited during the excitation period increases the proportion of blue light of the illumination light.
  • adjusting the light intensity in the different periods of the laser light is achieved by adjusting the magnitude of the current of the light source 12.
  • the intensity of the laser light emitted by the light source 12 increases; when the current of the light source 12 decreases, the intensity of the laser light emitted by the light source 12 decreases.
  • the area of the plurality of regions of the wavelength conversion device 13 can be adjusted as needed.
  • the intensity of the excited light after passing through the specific region of the wavelength conversion device 13 is correspondingly increased or decreased, thereby adjusting the The proportion of light of a particular color in the illumination.
  • the wavelength conversion device 13 includes a blue phosphor region and a green phosphor region.
  • the area of the blue phosphor region can be increased while being reduced.
  • the area of the green phosphor is small such that the blue light after passing through the blue phosphor region is increased by the laser light, and the green phosphor after passing through the green phosphor region is reduced, thereby increasing the proportion of blue light in the laser.
  • the purpose of increasing the proportion of blue light in the illumination light is achieved.
  • the wavelength conversion device 13 is provided with an adjustment mechanism capable of adjusting the area ratio of different regions on the wavelength conversion device 13. Specifically, the adjusting mechanism can achieve the purpose of adjusting the area ratio of different regions by shielding a partial region.
  • the wavelength conversion device 13 includes a blue phosphor layer. It can be understood that since the spectral component of the blue laser is narrow, a wide-band blue laser can be formed when the narrow-band blue excitation light excites the blue phosphor layer, thereby facilitating the user to distinguish different organs of the sample. Or an image of the organization.
  • the light color ratio of the different colors in the illumination light can be adjusted by adjusting the area ratio of the different filter regions on the filter device 14.
  • the different filter regions on the filter device 14 can be adjusted as needed, so that the intensity of the light after being filtered by the filter device 14 after the wavelength conversion device 13 is changed, thereby adjusting
  • the different colors are affected by the proportion of the laser light, and the purpose of adjusting the proportion of light of different colors in the illumination light is achieved.
  • the filter device includes a blue filter region and a green filter region.
  • the area of the blue filter region can be increased while being reduced.
  • the area of the green filter region is small, so that the blue light filtered through the blue filter region is increased, and the green light filtered through the green filter region is reduced, thereby achieving the purpose of increasing the proportion of blue light in the illumination light. .
  • the filter device 14 is provided with an adjustment mechanism capable of adjusting the area ratio of different filter regions on the filter device 14.
  • the adjusting mechanism can achieve the purpose of adjusting the area ratio of different filter areas by shielding a part of the filter area.
  • the endoscope insertion portion 20 includes a light diffusing body 21 and a lens group 22.
  • the light diffusing body 21 and the lens group 22 are disposed on a propagation path of light emitted from the light source device 10.
  • the light diffusing body 21 is configured to illuminate the to-be-detected organ or tissue after the laser light of the plurality of colors generated by the filter device 14 is time-divisioned.
  • the lens group 22 is configured to adjust a light distribution angle of the reflected light to focus the light reflected through the to-be-detected organ or tissue, thereby enabling the reflected light to be more concentratedly transmitted to the processor 30, and correspondingly Imaging on the shooting surface.
  • the processor 30 includes an imaging element 31, an imaging control unit 32, an image processing unit 33, a second control unit 34, and a storage unit 35.
  • the imaging element 31, the imaging control unit 32, the image processing unit 33, the second control unit 34, and the storage unit 35 are electrically connected together.
  • the imaging element 31 is preferably a light field camera that captures an observation portion of an organ or tissue to be examined illuminated by illumination light from the light source device 10, and receives different timings.
  • the optical signal is converted into a video signal.
  • the imaging element may also be other imaging devices, such as a color CCD.
  • the light field camera includes a black and white CCD chip capable of recording optical signals of different depths of field (hierarchy, depth), and is also capable of converting optical signals of respective colors generated by the filtering device into electrical signals.
  • the imaging element 31 has a imaging surface (not shown) such that light reflected via the organ or tissue to be examined can be imaged on the imaging surface of the imaging element 31.
  • the imaging control unit 32 is connected to the second control unit 34 in the processor 30, and inputs a drive signal to the imaging element 31 in synchronization with the basic clock signal input from the second control unit 34.
  • the imaging element 31 outputs an imaging signal to the image processor 33 at a predetermined frame rate based on a drive signal from the imaging control unit 32.
  • the image processor 33 performs image signal processing on the photographing signal output from the photographing element 31, that is, converts the image data into a video signal such as a composite signal or a component signal to generate image data.
  • the storage unit 35 is configured to store, but is not limited to, the image data generated by the image processor 33 and the proportion data of the light source device 10 that can adjust the respective primary colors of light, and thus can be selected by the user during use.
  • the imaging control unit 32 can control the start, end, drive time, synchronization timing, and the like of the respective portions of the imaging element 31.
  • FIG. 5 shows an imaging mode in which the imaging control unit 32 controls the imaging element 31.
  • the imaging device 31 performs an accumulation operation of accumulating signal charges and a reading operation of reading accumulated signal charges during one frame period under the control of the imaging control unit 32.
  • image light of three colors of blue light, green light, and red light is sequentially captured, and signal charges are accumulated, and the captured signals are sequentially outputted as blue light, green light, and red light according to the accumulated signal charge.
  • the above operation is repeated during the period in which the organ or tissue observation mode is to be examined.
  • the image processing unit 33 is provided with a plurality of processing units in order to increase the pixels of the imaging element 31, reduce the memory of the image data, and increase the processing speed of the image data.
  • the image processing unit 33 includes a Blu-ray image conversion unit 331, a green light image conversion unit 332, and a red light map.
  • the blue light image conversion unit 331 is configured to process a blue light signal of each frame image, and convert the corresponding blue light signal into a surface layer, a middle layer, and a deep layer signal of the to-be-detected organ or tissue.
  • the green light image conversion unit 332 is configured to process the green light signal of each frame image, and convert the corresponding green light signal into a surface layer, a middle layer, and a deep layer signal of the to-be-detected organ or tissue.
  • the red light image conversion unit 333 is configured to process a red light signal of each frame image, and convert the corresponding red light signal into a surface layer, a middle layer, and a deep layer signal of the to-be-detected organ or tissue.
  • the image processor 33 further includes an image combining unit 334, configured to combine the first surface layer signal, the second surface layer signal, and the third surface layer signal to obtain A surface image signal of the organ or tissue to be examined.
  • the image combining unit 334 is further configured to combine the first middle layer signal, the second middle layer signal, and the third middle layer signal to obtain a middle layer image signal of the organ or tissue to be examined.
  • the image combining unit 334 is further configured to combine the first deep layer signal, the second deep layer signal, and the third deep layer signal to obtain a deep image signal of the organ or tissue to be examined.
  • the surface, middle and deep images of the organ or tissue to be examined are composed of three signals of blue light, green light and red light, so the blue light obtained by the image processor 33 on the imaging element 31 is The green light and the red light signal are distinguished at different depths to separate blue, green, and red light signals of respective depths, and then combine blue, green, and red light signals to obtain a surface layer of the organ or tissue to be examined. , middle and deep image signals.
  • the blue, green, and red light signals obtained by the imaging element 31 can distinguish between blue, green, and red light of different depths by a software algorithm.
  • the first control unit 40 is configured to store parameter information of different organs or tissues, and is convenient for the user to input parameters or adjust the working mode of the light source device 10. Specifically, the first control unit 40 stores therein light absorption parameters of different tissues or organs, which can input signals to the light source device 10 according to different organs that are photographed to control different components in the light output of the light source device. For example, when taking an image of the stomach and taking an image of the intestine, the user can input different signals according to the control 40 to adjust different modes of operation of the light source device 10.
  • the processor 30 can control the display unit 50 to generate the image processor 33
  • the image data is converted into a composite signal or a component signal to display a clear image.
  • the display portion 50 includes a first display area 51, a second display area 52, and a third display area 53.
  • the first display area 51 is configured to display a surface layer image of the organ or tissue to be inspected
  • the second display area 52 is used to display a middle layer image of the organ or tissue to be inspected
  • the third display area 53 A deep image for displaying the organ or tissue to be examined.
  • the endoscope system 100 further includes an endoscope operating portion (not shown), a power cable (not shown), and an optical fiber (not shown).
  • the endoscope operating portion is disposed at the Between the light source device 10 and the processor 30, the power supply cable is used to establish a communication connection between the light source device 10 and the endoscope insertion portion 20 and the processor 30, and the optical fiber is used for conducting The light emitted by the light source device 10 is sent to the organ or tissue to be examined, and the light reflected by the organ or tissue to be examined is transmitted to the processor 30.
  • the endoscope system of the present invention is provided with a light source device having an adjustable ratio of respective primary colors of blue light, green light, and red light, that is, the light source device can be different according to different ratios of light absorption rates of the organ or tissue to be examined.
  • a light source of a primary color component such that the imaging element of the endoscope system is capable of directly acquiring an optical signal.
  • the endoscope system of the present invention uses a light field camera as an imaging element, which not only can clearly image the observed part of the organ or tissue to be examined, but also can display the true color of the image, thereby facilitating the user to perform internal organization of the sample. Observation and diagnosis.

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Abstract

An endoscope system (100), comprising an endoscope insertion portion (20), a light source apparatus (10), and a processor (30). The endoscope insertion portion (20) is configured for insertion into an organ or tissue of interest. The light source apparatus (10) comprises a light source (12) for emitting exciting light and a wavelength conversion device (13) for generating excited light under excitation of the exciting light. The exciting light and excited light are directed to the organ or tissue of interest through the endoscope insertion portion (20), and the proportion of exciting light to excited light may be adjusted depending on the organ or tissue of interest. The processor (30) comprises an imaging element (31), which is a light field camera. The light field camera photographs the observation site of the organ or tissue of interest illuminated by light emitted from the light source apparatus (10), and different optical signals are received according to a time sequence. The light source apparatus (10) can be adapted to light sources of varying primary color composition to suit different light absorptivities of the organ or tissue of interest, and can produce clear images of observation sites at different depths within the organ or tissue of interest.

Description

内窥镜系统及光源装置Endoscope system and light source device 技术领域Technical field
本发明涉及医学光学技术领域,尤其是一种内窥镜系统及光源装置。The invention relates to the field of medical optical technology, in particular to an endoscope system and a light source device.
背景技术Background technique
在检体内部的诊断中,通常会使用具有内窥镜、光源装置、处理器及显示器等构成的内窥镜系统,以对生物体组织的表层及中深层组织进行观察。在内窥镜系统进行检体内部观察时,针对不同深度的组织进行观察时,需要用特定波段的光对观察深度的组织进行照明,并且对拍摄部准确调焦后才能对观察的组织清晰成像。In the diagnosis inside the specimen, an endoscope system including an endoscope, a light source device, a processor, a display, and the like is generally used to observe the surface layer and the medium-deep tissue of the living tissue. When the endoscope system performs internal observation of the specimen, when observing the tissue at different depths, it is necessary to illuminate the tissue of the observation depth with light of a specific wavelength band, and the image of the observed portion can be accurately focused before the observed tissue can be clearly imaged. .
现有的光源装置,其光源通常采用氙灯、发光二极管(Light Emitting Diode,LED)以及激光视盘(Laser disc,LD)加受激光粉的方式来产生照明的白光。由于待检器官或组织对于不同波长的光吸收率不同,经组织反射后的光的光谱成分与照射光有较大的差异。如果采用纯白的白光进行照明,反射光在经电荷藕合器件图像传感器(Charge Coupled Device,CCD)产生的图像信号用于显示时得到的图像色调会偏移,从而不利于使用者进行观察和判断。针对上述问题,内窥系统采用图像处理的方式,将CCD采集的光信号强度进行放大/缩小,从而得到适于观察的图像。虽然这种处理方式比较简单,但是由于采集信号中噪声的影响,其准确率偏低。当光信号强度被以图像处理的方式放大时,其噪声强度也会被放大,而信号强度被缩小时,则白白损失了光能。In the conventional light source device, the light source is usually a xenon lamp, a light emitting diode (LED), and a laser disc (LD) plus a laser powder to generate white light for illumination. Since the light absorption rate of the organ or tissue to be examined is different for different wavelengths, the spectral composition of the light reflected by the tissue is largely different from the illumination light. If white light is used for illumination, the image of the reflected light generated by the charge coupled device image sensor (CCD) is used to display the image tones, which is unfavorable for the user to observe and Judge. In response to the above problem, the endoscopic system adopts an image processing method to enlarge/reduce the intensity of the optical signal collected by the CCD, thereby obtaining an image suitable for observation. Although this processing method is relatively simple, its accuracy is low due to the influence of noise in the collected signal. When the optical signal intensity is amplified by image processing, the noise intensity is also amplified, and when the signal intensity is reduced, the light energy is lost in vain.
对不同深度的组织进行观察时,不仅需要能够增强成像的照明光,也需要拍摄部对观察的组织清晰成像。内窥镜系统的摄像元件一般采用彩色或者黑白CCD,可以记录成像面的光线强度和分布。但是这种摄像元件的景深和 光圈存在难以调谐的矛盾,获取大的景深需要减小光圈,此时信噪比降低会出现噪点;而大的光圈会使得景深小,拍摄时需要对成像面精准对焦,同时背景模糊。在观察不同深度的组织、血管时,精准对焦比较困难,容易造成误判或错判。When observing tissues of different depths, it is necessary to not only enhance the illumination light for imaging, but also to clearly image the observed tissue by the imaging unit. The imaging elements of the endoscope system generally use a color or black-and-white CCD to record the light intensity and distribution of the imaging surface. But the depth of field of this camera element There is a contradiction in the aperture that is difficult to tune. To obtain a large depth of field, it is necessary to reduce the aperture. At this time, the signal-to-noise ratio is reduced, and noise is generated. The large aperture causes the depth of field to be small, and the imaging surface needs to be accurately focused while the background is blurred. When observing tissues and blood vessels of different depths, precise focusing is difficult, and it is easy to cause misjudgment or misjudgment.
发明内容Summary of the invention
鉴于以上内容,有必要提供一种对待检器官或组织不同深度的观察部位清晰成像的内窥镜系统。In view of the above, it is necessary to provide an endoscope system that clearly images the observation sites of different depths of the organ or tissue to be examined.
本发明还有必要提供一种提高光源利用率的光源装置,所述光源装置能够根据待检器官或组织对光吸收率的不同配比不同基色光成分的光源。The present invention also necessitates a light source device for improving the utilization of a light source, which is capable of matching light sources of different primary color light components according to different light absorption rates of an organ or tissue to be examined.
本发明提供一种内窥镜系统,包括:The invention provides an endoscope system comprising:
内窥镜插入部,用于插入到待检器官或组织内;An endoscope insertion portion for insertion into an organ or tissue to be examined;
光源装置,其包括发出激发光的光源,通过所述激发光激发而产生受激光的波长转换装置,所述激发光和所述受激光形成照明光并通过所述内窥镜插入部导向所述待检器官或组织,所述照明光中不同颜色光的占比根据所述待检器官或组织可调节;a light source device comprising a light source that emits excitation light, which is excited by the excitation light to generate a laser-converted wavelength conversion device, the excitation light and the laser-receiving light forming illumination light and being guided by the endoscope insertion portion An organ or tissue to be examined, wherein the proportion of light of different colors in the illumination light is adjustable according to the organ or tissue to be examined;
处理器,包括拍摄元件,所述拍摄元件为光场相机,所述光场相机对来自所述光源装置的照明光照明的待检器官或组织的观察部位进行拍摄,并按时序接收不同光信号并转换为视频信号;及The processor includes a photographing component, wherein the photographing component is a light field camera, and the light field camera photographs an observation portion of an organ or tissue to be examined illuminated by illumination light from the light source device, and receives different optical signals in time series And converted to a video signal; and
显示部,所述显示部用于接收所述处理器传输的视频信号并显示所述观察部位的图像。a display unit configured to receive a video signal transmitted by the processor and display an image of the observed portion.
在一实施例中,所述内窥镜系统还包括滤光装置,所述滤光装置用于对所述波长转换装置产生的受激光进行过滤,所述照明光中不同颜色光占比通过调节所述光源的光强度及/或调节所述波长转换装置及/或调节所述滤光装置来实现。In an embodiment, the endoscope system further includes a filter device for filtering the laser light generated by the wavelength conversion device, wherein the proportion of light of different colors in the illumination light is adjusted The light intensity of the light source and/or adjustment of the wavelength conversion device and/or adjustment of the filter device are achieved.
在一实施例中,所述光源装置还包括光源控制部,所述光源控制部调节所述光源同一脉冲区间内不同时段的电流大小从而调节所述光源的光强度。 In an embodiment, the light source device further includes a light source control portion that adjusts a current magnitude of the light source at different periods in the same pulse interval to adjust the light intensity of the light source.
在一实施例中,所述波长转换装置包括多个区域,所述区域承载或不承载波长转换材料或承载不同的波长转换材料,所述波长转换装置进一步包括调节机构,所述调节机构调节多个所述区域的面积占比以调节所述照明光中不同颜色光占比。In an embodiment, the wavelength conversion device comprises a plurality of regions carrying or not carrying a wavelength converting material or carrying different wavelength converting materials, the wavelength converting device further comprising an adjusting mechanism, the adjusting mechanism adjusting The area ratio of the regions is adjusted to adjust the proportion of light of different colors in the illumination light.
在一实施例中,所述滤光装置包括多个滤光区和调节机构,所述调节机构调节所述滤光区的面积占比以调节所述照明光中不同颜色光占比。In an embodiment, the filter device includes a plurality of filter zones and an adjustment mechanism, the adjustment mechanism adjusting an area ratio of the filter zones to adjust a ratio of light of different colors in the illumination light.
在一实施例中,所述光场相机包括黑白电荷耦合器件芯片,所述黑白电荷耦合器件芯片用于记录所述待检器官或组织不同景深的光信号。In an embodiment, the light field camera comprises a black and white charge coupled device chip for recording optical signals of different depths of field of the organ or tissue to be examined.
在一实施例中,所述处理器包括红色图像转换部、绿色图像转换部及蓝色图像转换部,所述红色图像转换部用于对每一帧图像的红色信号进行处理,并将对应的红色信号转换为所述待检器官或组织的第一表层、第一中层、第一深层信号,所述绿色图像转换部用于对每一帧图像的绿色信号进行处理,并将对应的绿色信号转换为所述待检器官或组织的第二表层、第二中层、第二深层信号,所述蓝色图像转换部用于对每一帧图像的蓝色信号进行处理,并将对应的蓝色信号转换为所述待检器官或组织的第三表层、第三中层、第三深层信号。In an embodiment, the processor includes a red image conversion unit, a green image conversion unit, and a blue image conversion unit, and the red image conversion unit is configured to process a red signal of each frame image, and corresponding The red signal is converted into a first surface layer, a first middle layer, and a first deep layer signal of the organ or tissue to be inspected, and the green image conversion unit is configured to process the green signal of each frame image, and the corresponding green signal Converting to a second skin layer, a second middle layer, and a second deep layer signal of the organ or tissue to be examined, the blue image converting portion is configured to process a blue signal of each frame image, and corresponding blue The signal is converted to a third surface layer, a third middle layer, and a third deep layer signal of the organ or tissue to be examined.
在一实施例中,所述处理器进一步包括图像组合部,所述图像组合部用于将所述第一表层信号、所述第二表层信号和所述第三表层信号进行组合,以得到所述待检器官或组织的表层图像信号;将所述第一中层信号、所述第二中层信号及所述第三中层信号进行组合,以得到所述待检器官或组织的中层图像信号;以及将所述第一深层信号、所述第二深层信号及所述第三深层信号进行组合,以得到所述待检器官或组织的深层图像信号。In an embodiment, the processor further includes an image combining unit, where the image combining unit is configured to combine the first surface layer signal, the second surface layer signal, and the third surface layer signal to obtain a Determining a surface image signal of the organ or tissue to be examined; combining the first intermediate layer signal, the second intermediate layer signal, and the third intermediate layer signal to obtain a middle layer image signal of the organ or tissue to be examined; Combining the first deep layer signal, the second deep layer signal and the third deep layer signal to obtain a deep image signal of the organ or tissue to be examined.
在一实施例中,所述显示部包括用于显示所述待检器官或组织的表层图像的第一显示区、用于显示所述待检器官或组织的中层图像的第二显示区及用于显示所述待检器官或组织的深层图像的第三显示区。In an embodiment, the display portion includes a first display area for displaying a surface layer image of the organ or tissue to be examined, a second display area for displaying a middle layer image of the object or tissue to be examined, and And displaying a third display area of the deep image of the organ or tissue to be examined.
本发明还提供一种光源装置,所述光源装置包括发出激发光的光源,及通过所述激发光激发而产生受激光的波长转换装置,所述激发光和所述受激 光形成照明光出射,所述照明光中不同颜色光的占比可调节。The present invention also provides a light source device including a light source that emits excitation light, and a wavelength conversion device that generates laser light by excitation of the excitation light, the excitation light and the excitation The light forms illumination light, and the proportion of light of different colors in the illumination light is adjustable.
相较于现有技术,本发明的内窥镜系统,通过设置可调节照明光占比的光源装置及能够对来自所述光源装置的射出光照明的待检器官或组织的观察部位进行拍摄的拍摄元件。此外,本发明的内窥镜系统采用光场相机作为拍摄元件,其不仅能够对待检器官或组织的观察部位成清晰像,并且图像能够显示真实的色彩,从而方便使用者对检体的内部组织进行观察和诊断。本发明的内窥镜系统能够对观察的不同深度组织清晰成像。本发明还提供一种光源装置,其能够根据待检器官或组织对光吸收率的不同配比不同基色光成分的光源,以使所述内窥镜系统的拍摄部能够对观察的组织清晰成像。Compared with the prior art, the endoscope system of the present invention provides a light source device capable of adjusting the proportion of illumination light and an observation portion of an organ or tissue to be examined that can illuminate the emitted light from the light source device. Shooting components. In addition, the endoscope system of the present invention employs a light field camera as a photographing element, which can not only provide a clear image of an observation portion of an organ or tissue to be examined, but also an image capable of displaying a true color, thereby facilitating the user's internal organization of the specimen. Observe and diagnose. The endoscope system of the present invention is capable of clearly imaging the different depths of tissue observed. The present invention also provides a light source device capable of matching light sources of different primary color light components according to different light absorption rates of an organ or tissue to be examined, so that the imaging portion of the endoscope system can clearly image the observed tissue. .
附图说明DRAWINGS
图1是本发明第一实施例的内窥镜系统的框架图。1 is a skeleton view of an endoscope system according to a first embodiment of the present invention.
图2是滤光装置中各颜色光段所占角度占比的示意图。2 is a schematic view showing the proportion of the angle of the light segments of each color in the filter device.
图3是待检器官或组织对不同波长的照明光的吸收系数曲线图。Fig. 3 is a graph showing the absorption coefficient of an organ or tissue to be examined for illumination light of different wavelengths.
图4是所述待检器官或组织对不同波长的吸收光、照明光和反射光的光谱示意图。图5是光场相机的拍摄动作的示意图。4 is a schematic view showing the spectrum of absorbed light, illumination light, and reflected light of different wavelengths of the organ or tissue to be examined. Fig. 5 is a schematic view showing a photographing operation of a light field camera.
图6是本发明第一实施例的内窥镜系统的框架图。Fig. 6 is a skeleton diagram of an endoscope system according to a first embodiment of the present invention.
图7是显示部的示意图。Fig. 7 is a schematic view of a display unit.
主要元件符号说明Main component symbol description
内窥镜系统 Endoscope system 100100
光源装置 Light source device 1010
光源控制部Light source control unit 1111
光源 light source 1212
波长转换装置 Wavelength conversion device 1313
滤光装置 Filter device 1414
滤光片Filter 140140
红光滤光片部Red light filter unit 141141
绿光滤光片部 Green filter unit 142142
蓝光滤光片部Blue light filter section 143143
内窥镜插入部 Endoscope insertion 2020
散光体Astigmatism 21twenty one
透镜组Lens group 22twenty two
处理器 processor 3030
拍摄元件 Shooting component 3131
拍摄控制器 Shooting controller 3232
图像处理器 Image processor 3333
蓝光图像转换部Blu-ray image conversion unit 331331
绿光图像转换部Green light image conversion unit 332332
红光图像转换部Red light image conversion unit 333333
图像组合部 Image combination department 334334
第二控制部 Second control unit 3434
存储部 Storage department 3535
第一控制部 First control department 4040
显示部 Display department 5050
第一显示区 First display area 5151
第二显示区 Second display area 5252
第三显示区 Third display area 5353
如下具体实施例将结合上述附图进一步说明本发明。The invention will be further illustrated by the following detailed description in conjunction with the accompanying drawings.
具体实施例Specific embodiment
为了简明清楚地进行说明,在恰当的地方,相同的标号在不同图式中被重复地用于标示对应的或相类似的元件。此外,为了提供对此处所描述实施例全面深入的理解,说明书中会提及许多特定的细节。然而,本领域技术人员可以理解的是此处所记载的实施例也可以不按照这些特定细节进行操作。在其他的一些情况下,为了不使正在被描述的技术特征混淆不清,一些方法、流程及元件并未被详细地描述。图式并不一定需要与实物的尺寸等同。为了更好地说明细节及技术特征,图式中特定部分的展示占比可能会被放大。说明书中的描述不应被认为是对此处所描述的实施例范围的限定。For the sake of clarity and clarity, where appropriate, the same reference numerals are used to identify corresponding or similar elements in different drawings. In addition, many specific details are mentioned in the specification in order to provide a thorough understanding of the embodiments described herein. However, it will be understood by those skilled in the art that the embodiments described herein may also be practiced without these specific details. In other instances, some methods, procedures, and components have not been described in detail in order not to obscure the technical features being described. The schema does not necessarily need to be the same as the size of the object. In order to better illustrate the details and technical features, the proportion of display in a particular part of the drawing may be magnified. The description in the specification is not to be construed as limiting the scope of the embodiments described herein.
请参阅图1,本发明第一实施例的内窥镜系统100的示意图。所述内窥镜系统100包括光源装置10、内窥镜插入部20、处理器30、第一控制部40及显示部50。所述光源装置10用于产生照明光并传输至所述内窥镜插入部20以照亮待检器官或组织,所述拍摄装置30用于对所述待检器官或组织进行拍摄并处理所述拍摄图像,所述第一控制部40用于设置或调整所述光源装置10的不同模式以对不同器官或组织进行 照明,所述显示部50用于显示所述处理器30传输的图像信息。Referring to Figure 1, a schematic diagram of an endoscope system 100 in accordance with a first embodiment of the present invention. The endoscope system 100 includes a light source device 10, an endoscope insertion portion 20, a processor 30, a first control portion 40, and a display portion 50. The light source device 10 is configured to generate illumination light and transmit it to the endoscope insertion portion 20 to illuminate an organ or tissue to be examined, and the photographing device 30 is configured to photograph and process the organ or tissue to be examined. The captured image is used to set or adjust different modes of the light source device 10 to perform different organs or tissues. For illumination, the display unit 50 is configured to display image information transmitted by the processor 30.
在一实施例中,所述光源装置10配置在所述内窥镜插入部20的前端,所述处理器30配置在所述内窥镜插入部20的后端。可以理解的,在其他实施例中,所述光源装置10和所述处理器30可以设置在所述内窥镜插入部20的同侧。所述第一控制部40及所述显示部50与所述处理器30电性连接。In an embodiment, the light source device 10 is disposed at a front end of the endoscope insertion portion 20, and the processor 30 is disposed at a rear end of the endoscope insertion portion 20. It can be understood that in other embodiments, the light source device 10 and the processor 30 may be disposed on the same side of the endoscope insertion portion 20. The first control unit 40 and the display unit 50 are electrically connected to the processor 30.
所述光源装置10用于供给对所述待检器官或组织的观察部位进行照明的照明光。所述光源装置10包括光源控制部11、光源12、波长转换装置13及滤光装置14。所述光源控制部11能够对所述光源12进行驱动控制。所述光源12能够发出激发光,所述波长转换装置13通过所述激发光激发而发出受激光,所述激发光和所述受激光共同组成用于照明所述待检器官或组织的照明光。The light source device 10 is for supplying illumination light that illuminates an observation portion of the organ or tissue to be examined. The light source device 10 includes a light source control unit 11, a light source 12, a wavelength conversion device 13, and a filter device 14. The light source control unit 11 can drive and control the light source 12. The light source 12 is capable of emitting excitation light, and the wavelength conversion device 13 emits a laser beam by excitation of the excitation light, and the excitation light and the laser light source together constitute illumination light for illuminating the organ or tissue to be examined. .
具体地,所述波长转换装置13上可设置多个区域,所述多个区域上分别承载或不承载波长转换材料或承载不同的波长转换材料,以使得所述光源12发出的激发光照射在所述波长转换装置13上能够产生特定光谱的受激光。所述波长转换材料例如是,但不局限于荧光粉、量子点或染料。所述受激光可为蓝色、绿色或黄色受激光等,其取决于所述波长转换材料的材料特性。Specifically, a plurality of regions may be disposed on the wavelength conversion device 13, and the plurality of regions respectively carry or do not carry a wavelength conversion material or carry different wavelength conversion materials, so that the excitation light emitted by the light source 12 is irradiated The wavelength conversion device 13 is capable of generating a laser beam of a specific spectrum. The wavelength converting material is, for example, but not limited to, a phosphor, a quantum dot or a dye. The laser light may be a blue, green or yellow laser or the like depending on the material properties of the wavelength converting material.
所述待检器官或组织例如是,但不局限于,耳朵、鼻子、喉咙、直肠、膀胱组织、关节、黏膜组织、血管、静脉血管及动脉血管等。The organ or tissue to be examined is, for example, but not limited to, an ear, a nose, a throat, a rectum, a bladder tissue, a joint, a mucosa tissue, a blood vessel, a venous blood vessel, and an arterial blood vessel.
可以理解的,所述光源控制部11能够对所述光源装置10的各部分的驱动开始、结束、驱动时间、同步定时等控制。It is to be understood that the light source control unit 11 can control the start, end, drive time, synchronization timing, and the like of the respective portions of the light source device 10.
所述光源12为激光光源,具体地,为蓝色激光二极管。所述光源12能够发出蓝色激发光。在本实施例中,所述激发光是中心波长为445纳米(nm)的蓝色激光。所述光源12发出的蓝色激光能够通过光纤传导给所述波长转换装置13。在本实施例中,所述波长转换装置13上具有黄色荧光粉,因此所述光源12发出的蓝色激光激发所述 波长转换装置13后会产生黄色受激光,从而所述蓝色激发光和所述黄色受激光混合后产生用于照明的白光,所述照明光通过所述内窥镜插入部20导向所述待检器官或组织,以便于观察者对所述待检器官或组织进行观察。The light source 12 is a laser light source, specifically a blue laser diode. The light source 12 is capable of emitting blue excitation light. In the present embodiment, the excitation light is a blue laser having a center wavelength of 445 nanometers (nm). The blue laser light emitted by the light source 12 can be conducted to the wavelength conversion device 13 through an optical fiber. In this embodiment, the wavelength conversion device 13 has a yellow phosphor thereon, so the blue laser light emitted by the light source 12 excites the After the wavelength conversion device 13 generates a yellow laser light, the blue excitation light and the yellow laser light are mixed to generate white light for illumination, and the illumination light is guided to the object through the endoscope insertion portion 20. The organ or tissue is examined to facilitate observation by the observer of the organ or tissue to be examined.
请一并参阅图1和图2,所述滤光装置14设置于所述波长转换装置13的后方,用于过滤所述照明光,以使得所述照明光的颜色更为纯正。所述滤光装置14包括滤光片140。所述滤光片140为圆板形状,沿圆周方向分割为若干部分,并且所述滤光片140的每一部分能够使特定波长范围的光透过。Referring to FIG. 1 and FIG. 2 together, the filter device 14 is disposed behind the wavelength conversion device 13 for filtering the illumination light to make the illumination light color more pure. The filter device 14 includes a filter 140. The filter 140 has a circular plate shape and is divided into a plurality of portions in the circumferential direction, and each portion of the filter 140 is capable of transmitting light of a specific wavelength range.
在本实施例中,所述滤光片140包括多个滤光区,所述滤光区用于使得特定波长范围的光通过。可以理解,所述滤光区可以为红色滤光区、蓝色滤光区、绿色滤光区、黄色滤光区等,其可根据需要进行设置。因此,由于所述滤光装置14不停转动,当所述白光经过所述滤光装置14的滤光片140后,能够时序产生特定颜色的时序光。In the present embodiment, the filter 140 includes a plurality of filter regions for passing light of a specific wavelength range. It can be understood that the filter region can be a red filter region, a blue filter region, a green filter region, a yellow filter region, etc., which can be set as needed. Therefore, since the filter device 14 is continuously rotated, when the white light passes through the filter 140 of the filter device 14, time-series light of a specific color can be generated at a time.
图示3展示了所述待检器官或组织对不同波长的照明光的吸收系数曲线。如图3所示,所述待检器官或组织对各个颜色(或是波长)的光的吸收率不同。Figure 3 shows the absorption coefficient curve of the organ or tissue to be examined for illumination light of different wavelengths. As shown in FIG. 3, the organ or tissue to be examined has different absorption rates for light of respective colors (or wavelengths).
进一步的,从图4中可以看出,所述待检器官或组织对蓝光的吸收系数较高,经由所述待检器官或组织反射的蓝光的光强度相较照射蓝光的光强度较低,可见所述蓝光在照射和反射的过程中损失多;所述待检器官或组织对红光的吸收系数较低,经由所述待检器官或组织反射的红光的光强度相对照射红光的光强度较高,可见所述红光在照射和反射的过程中的损失较少,因此为了使得所述照明光照射在所述待检器官或组织上能够显示出真实的图像,因此需要根据所述待检器官或组织的光吸收系数调整所述照明光中不同颜色光的占比。Further, it can be seen from FIG. 4 that the absorption coefficient of the blue light is higher in the organ or tissue to be examined, and the light intensity of the blue light reflected by the organ or tissue to be examined is lower than that of the blue light. It can be seen that the blue light is lost during the irradiation and reflection; the absorption coefficient of the red light is low in the organ or tissue to be examined, and the light intensity of the red light reflected through the organ or tissue to be examined is relatively illuminating the red light. The light intensity is high, and the red light is less likely to be lost during illumination and reflection. Therefore, in order to cause the illumination light to illuminate the organ or tissue to be examined, a real image can be displayed. The light absorption coefficient of the organ or tissue to be examined adjusts the proportion of light of different colors in the illumination light.
可以理解,对于待检的正常组织或病变组织,其对不同波长光的吸收率也会与正常组织有差别。为了让使用者能够明显区分不同组 织、病变组织及正常组织,可以根据其吸光系数的差异,用不同光谱成分的照明光来照明所述待检器官或组织。It can be understood that for normal tissues or diseased tissues to be examined, the absorption rate of light of different wavelengths is also different from that of normal tissues. In order to allow users to clearly distinguish between different groups The woven, diseased tissue and normal tissue can illuminate the organ or tissue to be examined with illumination light of different spectral components according to the difference in their absorption coefficients.
可以理解的,对于不同的器官或组织对不同波长的照明光的吸收系数不同,因此在确定所述出射光的基色光成分时,先要测试不同的器官或组织对不同波长的吸收(或反射)的光谱曲线,再根据所述器官或组织的吸收(或反射)情况调整所述出射光中不同颜色光的占比。It can be understood that the absorption coefficients of different wavelengths of illumination light are different for different organs or tissues, so when determining the primary color light component of the emitted light, firstly, different organs or tissues are tested for absorption (or reflection) of different wavelengths. The spectral curve, and then the proportion of light of different colors in the emitted light is adjusted according to the absorption (or reflection) of the organ or tissue.
在本实施方式中,能够通过调节所述激发光的光强度及/或调节所述波长转换装置及/或调节所述滤光装置的方式来实现调整所述照明光中不同颜色光占比的目的。下文将对上述实施方式进行进一步阐述。In this embodiment, it is possible to adjust the proportion of light of different colors in the illumination light by adjusting the light intensity of the excitation light and/or adjusting the wavelength conversion device and/or adjusting the filter device. purpose. The above embodiments will be further explained below.
在本实施方式中,所述光源装置10能够通过所述光源控制部11调节所述光源12同一脉冲周期内不同时段的激发光强度来调整所述照明光中的不同颜色光占比。In the present embodiment, the light source device 10 can adjust the intensity of the different colors of the illumination light by adjusting the intensity of the excitation light of the light source 12 for different periods in the same pulse period by the light source control unit 11.
具体地,所述光源12同一脉冲周期内的不同时段发出的激发光照射所述波长转换装置13的不同区域。例如,所述波长转换材料具有蓝色荧光粉区域和绿色荧光粉区域,所述光源12同一脉冲周期内具有对应所述黄色荧光粉区域的激发光时段和对应所述绿色区域的激发光时段。因此当需要提高所述照明光中蓝光的占比时,可使得所述光源对应蓝色荧光粉区域的激发光时段内的激发光强度提高,对应绿色荧光粉区域的激发光时段内的激发光强度不变,从而使得激发光照射在波长转换装置13的蓝色荧光粉区域后产生的蓝色受激光增多,同时绿色受激光保持不变,从而提高了受激光中蓝光的占比,进而达到提高了照明光中的蓝光占比的目的。Specifically, the excitation light emitted by the light source 12 at different periods in the same pulse period illuminates different regions of the wavelength conversion device 13. For example, the wavelength converting material has a blue phosphor region and a green phosphor region, and the light source 12 has an excitation light period corresponding to the yellow phosphor region and an excitation light period corresponding to the green region in the same pulse period. Therefore, when it is required to increase the proportion of blue light in the illumination light, the intensity of the excitation light in the excitation light period corresponding to the blue phosphor region may be increased, and the excitation light in the excitation light period corresponding to the green phosphor region may be increased. The intensity is constant, so that the blue light generated by the excitation light after being irradiated to the blue phosphor region of the wavelength conversion device 13 is increased by the laser, and the green laser is kept unchanged, thereby increasing the proportion of blue light in the laser, thereby achieving The purpose of increasing the proportion of blue light in the illumination light is improved.
可以理解,也可以通过保持光源12对应蓝光区域激发光时段内激发光强度不变,同时减小光源12对应绿色区域的激发光时段内的激发光强度的方式提高照明光的蓝光占比;亦或提高光源12对应蓝光区域激发光时段内激发光强度,同时减小光源12对应绿色区域的 激发光时段内的激发光强度的方式来提高照明光的蓝光占比。It can be understood that the blue light ratio of the illumination light can also be improved by keeping the excitation light intensity in the excitation light period of the blue light region corresponding to the light source 12 while reducing the intensity of the excitation light in the excitation light period corresponding to the green region of the light source 12; Or increasing the intensity of the excitation light in the excitation light period of the blue light region corresponding to the light source 12 while reducing the green area corresponding to the light source 12 The manner in which the intensity of the excitation light is excited during the excitation period increases the proportion of blue light of the illumination light.
在本实施方式中,调节所述激光不同时段内的光强度通过调节所述光源12的电流大小的方式实现。当所述光源12的电流增大时,所述光源12发出的激光强度增大;当所述光源12的电流减小时,所述光源12发出的激光强度减小。In the present embodiment, adjusting the light intensity in the different periods of the laser light is achieved by adjusting the magnitude of the current of the light source 12. When the current of the light source 12 increases, the intensity of the laser light emitted by the light source 12 increases; when the current of the light source 12 decreases, the intensity of the laser light emitted by the light source 12 decreases.
进一步地,在本实施方式中,能够通过调节所述波长转换装置13上不同区域的面积占比的方式来调整所述照明光中不同颜色光占比。Further, in the present embodiment, it is possible to adjust the ratio of the different colors of light in the illumination light by adjusting the area ratio of the different regions on the wavelength conversion device 13.
具体地,所述波长转换装置13的多个区域的面积可以根据需要进行调节。当所述光源12照射在所述波长转换装置13的特定区域的面积增大或减小时,经过所述波长转换装置13特定区域后的受激发光强度对应增大或减小,进而调整所述照明光中特定颜色光的占比。Specifically, the area of the plurality of regions of the wavelength conversion device 13 can be adjusted as needed. When the area of the specific region of the wavelength conversion device 13 is increased or decreased by the light source 12, the intensity of the excited light after passing through the specific region of the wavelength conversion device 13 is correspondingly increased or decreased, thereby adjusting the The proportion of light of a particular color in the illumination.
例如,所述波长转换装置13上包括蓝色荧光粉区域和绿色荧光粉区域,当需要提高所述照明光中蓝光占比时,可以通过增大所述蓝色荧光粉区域的面积,同时减小所述绿色荧光粉的面积,以使得经过蓝色荧光粉区域后的蓝色受激光增多,同时经过绿色荧光粉区域后的绿色荧光粉减小,从而提高了受激光中的蓝光占比,进而达到提高了照明光中的蓝光占比的目的。For example, the wavelength conversion device 13 includes a blue phosphor region and a green phosphor region. When it is required to increase the proportion of blue light in the illumination light, the area of the blue phosphor region can be increased while being reduced. The area of the green phosphor is small such that the blue light after passing through the blue phosphor region is increased by the laser light, and the green phosphor after passing through the green phosphor region is reduced, thereby increasing the proportion of blue light in the laser. In turn, the purpose of increasing the proportion of blue light in the illumination light is achieved.
可以理解,当所述波长转换装置13上不同荧光粉面积占比发生变化时,需要对应调整所述光源12的脉冲周期以与所述波长转换装置13相适配。进一步地,在本实施方式中,所述波长转换装置13上设置调节机构,所述调节机构能够调节所述波长转换装置13上不同区域的面积占比。具体地,所述调节机构可通过遮蔽部分区域的方式以实现调节不同区域面积占比的目的。It can be understood that when the proportion of different phosphor areas on the wavelength conversion device 13 changes, it is necessary to adjust the pulse period of the light source 12 to match the wavelength conversion device 13. Further, in the present embodiment, the wavelength conversion device 13 is provided with an adjustment mechanism capable of adjusting the area ratio of different regions on the wavelength conversion device 13. Specifically, the adjusting mechanism can achieve the purpose of adjusting the area ratio of different regions by shielding a partial region.
进一步地,在本实施方式中,所述波长转换装置13上包括蓝色荧光粉层。可以理解,由于蓝色激光的光谱成分较窄,当窄波段蓝色激发光激发所述蓝色荧光粉层后能够形成宽波段蓝色激光,从而有利于使用者区分所述检体的不同器官或组织的图像。 Further, in the present embodiment, the wavelength conversion device 13 includes a blue phosphor layer. It can be understood that since the spectral component of the blue laser is narrow, a wide-band blue laser can be formed when the narrow-band blue excitation light excites the blue phosphor layer, thereby facilitating the user to distinguish different organs of the sample. Or an image of the organization.
进一步地,在本实施方式中,能够通过调整所述滤光装置14上不同滤光区的面积占比的方式来调整所述照明光中不同颜色光占比。Further, in the present embodiment, the light color ratio of the different colors in the illumination light can be adjusted by adjusting the area ratio of the different filter regions on the filter device 14.
具体地,所述滤光装置14上不同滤光区可以根据需要进行调整,从而使得通过所述波长转换装置13后的受激光经过所述滤光装置14过滤后的光强度发生变化,进而调整所述不同颜色受激光的占比,达到调整所述照明光中不同颜色光占比的目的。Specifically, the different filter regions on the filter device 14 can be adjusted as needed, so that the intensity of the light after being filtered by the filter device 14 after the wavelength conversion device 13 is changed, thereby adjusting The different colors are affected by the proportion of the laser light, and the purpose of adjusting the proportion of light of different colors in the illumination light is achieved.
例如,所述滤光装置上包括蓝色滤光区和绿色滤光区,当需要提高所述照明光中的蓝光占比时,可以通过增大所述蓝色滤光区的面积,同时减小所述绿色滤光区的面积,以使得经过所述蓝色滤光区过滤出来的蓝光增多,同时经过绿色滤光区过滤后的绿光减少,进而达到提高照明光中蓝光占比的目的。For example, the filter device includes a blue filter region and a green filter region. When it is required to increase the proportion of blue light in the illumination light, the area of the blue filter region can be increased while being reduced. The area of the green filter region is small, so that the blue light filtered through the blue filter region is increased, and the green light filtered through the green filter region is reduced, thereby achieving the purpose of increasing the proportion of blue light in the illumination light. .
进一步地,在本实施方式中,所述滤光装置14上设置调节机构,所述调节机构能够调节所述滤光装置14上不同滤光区的面积占比。具体地,所述调节机构可通过遮蔽部分所述滤光区的方式以实现调节不同滤光区面积占比的目的。Further, in the embodiment, the filter device 14 is provided with an adjustment mechanism capable of adjusting the area ratio of different filter regions on the filter device 14. Specifically, the adjusting mechanism can achieve the purpose of adjusting the area ratio of different filter areas by shielding a part of the filter area.
可以理解,当需要调整所述照明光中不同颜色光占比时可通过上述三种方式单独使用或通过上述三种方式组合实现。It can be understood that when it is required to adjust the proportion of light of different colors in the illumination light, it can be used alone by the above three methods or by a combination of the above three methods.
所述内窥镜插入部20包括散光体21和透镜组22。所述散光体21和所述透镜组22设置在所述光源装置10发射出的光线的传播路径上。所述散光体21用于将所述滤光装置14时序产生的多种颜色的受激光匀光后对所述待检器官或组织进行照明。所述透镜组22用于配置调整反射光的配光角度,从而聚焦经由所述待检器官或组织反射的光线,进而能够使反射光线更为集中地传输至所述处理器30,并于对应的拍摄面上成像。The endoscope insertion portion 20 includes a light diffusing body 21 and a lens group 22. The light diffusing body 21 and the lens group 22 are disposed on a propagation path of light emitted from the light source device 10. The light diffusing body 21 is configured to illuminate the to-be-detected organ or tissue after the laser light of the plurality of colors generated by the filter device 14 is time-divisioned. The lens group 22 is configured to adjust a light distribution angle of the reflected light to focus the light reflected through the to-be-detected organ or tissue, thereby enabling the reflected light to be more concentratedly transmitted to the processor 30, and correspondingly Imaging on the shooting surface.
所述处理器30包括拍摄元件31、拍摄控制部32、图像处理部33、第二控制部34及存储部35。所述拍摄元件31、所述拍摄控制部32、所述图像处理部33、所述第二控制部34及所述存储部35电性连接在一起。 The processor 30 includes an imaging element 31, an imaging control unit 32, an image processing unit 33, a second control unit 34, and a storage unit 35. The imaging element 31, the imaging control unit 32, the image processing unit 33, the second control unit 34, and the storage unit 35 are electrically connected together.
在本实施例中,所述拍摄元件31优选为光场相机,所述光场相机对来自所述光源装置10的照明光照明的待检器官或组织的观察部位进行拍摄,并按时序接收不同光信号并转换为视频信号。在其他实施例中,所述拍摄元件还可以为其他拍摄装置,例如彩色CCD。所述光场相机包括黑白CCD芯片,所述黑白CCD芯片能够记录不同景深(层次、深度)的光信号,并且还能够将所述滤光装置产生的各中颜色的光信号转化为电信号。所述拍摄元件31具有拍摄面(图未示),从而经由所述待检器官或组织反射的光线能够在所述拍摄元件31的拍摄面成像。In the present embodiment, the imaging element 31 is preferably a light field camera that captures an observation portion of an organ or tissue to be examined illuminated by illumination light from the light source device 10, and receives different timings. The optical signal is converted into a video signal. In other embodiments, the imaging element may also be other imaging devices, such as a color CCD. The light field camera includes a black and white CCD chip capable of recording optical signals of different depths of field (hierarchy, depth), and is also capable of converting optical signals of respective colors generated by the filtering device into electrical signals. The imaging element 31 has a imaging surface (not shown) such that light reflected via the organ or tissue to be examined can be imaged on the imaging surface of the imaging element 31.
所述拍摄控制部32与所述处理器30内的第二控制部34连接,与从所述第二控制部34输入的基础时钟信号同步,向所述拍摄元件31输入驱动信号。所述拍摄元件31根据来自所述拍摄控制部32的驱动信号,以规定的帧频将拍摄信号输出至所述图像处理器33。所述图像处理器33对从所述拍摄元件31输出的拍摄信号执行图像信号处理,也即将图像数据变换为合成信号或是分量信号等视频信号,以生成图像数据。所述存储部35用于存储但不局限于由所述图像处理器33生成的图像数据及所述光源装置10的可调节各基色光的占比数据,因此使用时可供使用者选择。The imaging control unit 32 is connected to the second control unit 34 in the processor 30, and inputs a drive signal to the imaging element 31 in synchronization with the basic clock signal input from the second control unit 34. The imaging element 31 outputs an imaging signal to the image processor 33 at a predetermined frame rate based on a drive signal from the imaging control unit 32. The image processor 33 performs image signal processing on the photographing signal output from the photographing element 31, that is, converts the image data into a video signal such as a composite signal or a component signal to generate image data. The storage unit 35 is configured to store, but is not limited to, the image data generated by the image processor 33 and the proportion data of the light source device 10 that can adjust the respective primary colors of light, and thus can be selected by the user during use.
可以理解的,所述拍摄控制部32能够对所述拍摄元件31的各部分的驱动开始、结束、驱动时间、同步定时等控制。It is to be understood that the imaging control unit 32 can control the start, end, drive time, synchronization timing, and the like of the respective portions of the imaging element 31.
图5展示了所述拍摄控制部32控制所述拍摄元件31的拍摄模式。如图5所示,通过所述拍摄控制部32的控制,所述拍摄元件31在一帧的期间,进行蓄积信号电荷的蓄积动作,及读取蓄积信号电荷的读取动作。对于每一帧,依次拍摄蓝光、绿光、红光三种颜色的影像光,蓄积信号电荷,根据蓄积的信号电荷,依次输出拍摄信号蓝光、绿光、红光。上述动作在所述待检器官或组织观察模式的期间内反复进行。FIG. 5 shows an imaging mode in which the imaging control unit 32 controls the imaging element 31. As shown in FIG. 5, the imaging device 31 performs an accumulation operation of accumulating signal charges and a reading operation of reading accumulated signal charges during one frame period under the control of the imaging control unit 32. For each frame, image light of three colors of blue light, green light, and red light is sequentially captured, and signal charges are accumulated, and the captured signals are sequentially outputted as blue light, green light, and red light according to the accumulated signal charge. The above operation is repeated during the period in which the organ or tissue observation mode is to be examined.
可以理解的,为了提高所述拍摄元件31的像素,减小图像数据的内存及提高图像数据的处理速度,所述图像处理部33设有多个处理部。如图6所示,所述图像处理部33包括蓝光图像转换部331、绿光图像转换部332及红光图 像转换部333。所述蓝光图像转换部331用于对每一帧图像的蓝光信号进行处理,并将对应的蓝光信号转换为所述待检器官或组织的表层、中层、深层的信号。所述绿光图像转换部332用于对每一帧图像的绿光信号进行处理,并将对应的绿光信号转换为所述待检器官或组织的表层、中层、深层的信号。所述红光图像转换部333用于对每一帧图像的红光信号进行处理,并将对应的红光信号转换为所述待检器官或组织的表层、中层、深层的信号。It is to be understood that the image processing unit 33 is provided with a plurality of processing units in order to increase the pixels of the imaging element 31, reduce the memory of the image data, and increase the processing speed of the image data. As shown in FIG. 6, the image processing unit 33 includes a Blu-ray image conversion unit 331, a green light image conversion unit 332, and a red light map. Image conversion unit 333. The blue light image conversion unit 331 is configured to process a blue light signal of each frame image, and convert the corresponding blue light signal into a surface layer, a middle layer, and a deep layer signal of the to-be-detected organ or tissue. The green light image conversion unit 332 is configured to process the green light signal of each frame image, and convert the corresponding green light signal into a surface layer, a middle layer, and a deep layer signal of the to-be-detected organ or tissue. The red light image conversion unit 333 is configured to process a red light signal of each frame image, and convert the corresponding red light signal into a surface layer, a middle layer, and a deep layer signal of the to-be-detected organ or tissue.
进一步的,所述图像处理器33还包括图像组合部334,所述图像组合部334用于将所述第一表层信号、所述第二表层信号和所述第三表层信号进行组合,以得到所述待检器官或组织的表层图像信号。所述图像组合部334还用于将所述第一中层信号、所述第二中层信号及所述第三中层信号进行组合,以得到所述待检器官或组织的中层图像信号。所述图像组合部334还进一步用于将所述第一深层信号、所述第二深层信号及所述第三深层信号进行组合,以得到所述待检器官或组织的深层图像信号。Further, the image processor 33 further includes an image combining unit 334, configured to combine the first surface layer signal, the second surface layer signal, and the third surface layer signal to obtain A surface image signal of the organ or tissue to be examined. The image combining unit 334 is further configured to combine the first middle layer signal, the second middle layer signal, and the third middle layer signal to obtain a middle layer image signal of the organ or tissue to be examined. The image combining unit 334 is further configured to combine the first deep layer signal, the second deep layer signal, and the third deep layer signal to obtain a deep image signal of the organ or tissue to be examined.
可以理解的,所述待检器官或组织的表、中、深层图像均是由蓝光、绿光、红光三种信号组成的,因此所述图像处理器33对所述拍摄元件31获得的蓝光、绿光、红光信号进行不同深度的区分,以分离出各个深度的蓝光、绿光、红光信号,再组合蓝光、绿光、红光信号,从而得到所述待检器官或组织的表层、中层及深层的图像信号。It can be understood that the surface, middle and deep images of the organ or tissue to be examined are composed of three signals of blue light, green light and red light, so the blue light obtained by the image processor 33 on the imaging element 31 is The green light and the red light signal are distinguished at different depths to separate blue, green, and red light signals of respective depths, and then combine blue, green, and red light signals to obtain a surface layer of the organ or tissue to be examined. , middle and deep image signals.
可以理解的,所述拍摄元件31获得的蓝光、绿光、红光信号能够通过软件上的算法对不同深度的蓝光、绿光、红光进行区分。It can be understood that the blue, green, and red light signals obtained by the imaging element 31 can distinguish between blue, green, and red light of different depths by a software algorithm.
所述第一控制部40用于存储不同器官或组织的参数信息,并便于使用者输入参数或调整所述光源装置10的工作模式。具体地,所述第一控制部40内存储有不同组织或器官的吸光参数,其可根据拍摄的不同器官对所述光源装置10输入信号以控制所述光源装置输出光中的不同组分。例如,当拍摄胃部的图像和拍摄肠道的图像时,所述用户可以根据所述控制40输入不同的信号以调整所述光源装置10的不同工作模式。The first control unit 40 is configured to store parameter information of different organs or tissues, and is convenient for the user to input parameters or adjust the working mode of the light source device 10. Specifically, the first control unit 40 stores therein light absorption parameters of different tissues or organs, which can input signals to the light source device 10 according to different organs that are photographed to control different components in the light output of the light source device. For example, when taking an image of the stomach and taking an image of the intestine, the user can input different signals according to the control 40 to adjust different modes of operation of the light source device 10.
所述处理器30能够控制所述显示部50将所述图像处理器33生成 的图像数据变换为合成信号或是分量信号等视频信号,以显示清晰的图像。如图7所示,所述显示部50包括第一显示区51、第二显示区52及第三显示区53。所述第一显示区51用于显示所述待检器官或组织的表层图像,所述第二显示区52用于显示所述待检器官或组织的中层图像,以及所述第三显示区53用于显示所述待检器官或组织的深层图像。The processor 30 can control the display unit 50 to generate the image processor 33 The image data is converted into a composite signal or a component signal to display a clear image. As shown in FIG. 7, the display portion 50 includes a first display area 51, a second display area 52, and a third display area 53. The first display area 51 is configured to display a surface layer image of the organ or tissue to be inspected, the second display area 52 is used to display a middle layer image of the organ or tissue to be inspected, and the third display area 53 A deep image for displaying the organ or tissue to be examined.
可以理解的,所述内窥镜系统100还包括内窥镜操作部(图未示)、通电电缆(图未示)及光纤((图未示)。所述内窥镜操作部设置在所述光源装置10和所述处理器30之间,所述通电电缆用于将所述光源装置10、所述内窥镜插入部20与所述处理器30建立通信连接,所述光纤用于传导所述光源装置10发出的光线至所述待检器官或组织,再将所述待检器官或组织反射的光线传导至所述处理器30。It can be understood that the endoscope system 100 further includes an endoscope operating portion (not shown), a power cable (not shown), and an optical fiber (not shown). The endoscope operating portion is disposed at the Between the light source device 10 and the processor 30, the power supply cable is used to establish a communication connection between the light source device 10 and the endoscope insertion portion 20 and the processor 30, and the optical fiber is used for conducting The light emitted by the light source device 10 is sent to the organ or tissue to be examined, and the light reflected by the organ or tissue to be examined is transmitted to the processor 30.
本发明的内窥镜系统,通过设有蓝光、绿光、红光各基色占比可调的光源装置,也即所述光源装置能够根据待检器官或组织对光吸收率的不同配比不同基色光成分的光源,从而所述内窥镜系统的拍摄元件能够直接采集光信号。此外,本发明的内窥镜系统采用光场相机作为拍摄元件,不仅能够对待检器官或组织的观察部位成清晰像,并且图像能够显示真实的色彩,从而方便使用者对检体的内部组织进行观察和诊断。The endoscope system of the present invention is provided with a light source device having an adjustable ratio of respective primary colors of blue light, green light, and red light, that is, the light source device can be different according to different ratios of light absorption rates of the organ or tissue to be examined. A light source of a primary color component such that the imaging element of the endoscope system is capable of directly acquiring an optical signal. In addition, the endoscope system of the present invention uses a light field camera as an imaging element, which not only can clearly image the observed part of the organ or tissue to be examined, but also can display the true color of the image, thereby facilitating the user to perform internal organization of the sample. Observation and diagnosis.
上述实施例为本发明较佳的实施例,但本发明的实施例并不受上述实施例的限制,以上实施例仅是用于解释权利要求书。然本发明的保护范围并不局限于说明书。任何熟悉本技术领域的技术人员在本发明披露的技术范围内,可轻易想到的变化或者替换,都包含在本发明的保护范围之内。 The above embodiments are preferred embodiments of the present invention, but the embodiments of the present invention are not limited by the above embodiments, and the above embodiments are merely for explaining the claims. However, the scope of protection of the present invention is not limited to the description. Any changes or substitutions that are easily conceivable within the scope of the present invention are intended to be included within the scope of the present invention.

Claims (10)

  1. 一种内窥镜系统,包括:An endoscope system comprising:
    内窥镜插入部,用于插入到待检器官或组织内;An endoscope insertion portion for insertion into an organ or tissue to be examined;
    光源装置,其包括发出激发光的光源和通过所述激发光激发而产生受激光的波长转换装置,所述激发光和所述受激光形成照明光并通过所述内窥镜插入部导向所述待检器官或组织,所述照明光中不同颜色光的占比根据所述待检器官或组织可调节;a light source device including a light source that emits excitation light and a wavelength conversion device that generates laser light by excitation of the excitation light, the excitation light and the laser light receiving illumination light and being guided by the endoscope insertion portion An organ or tissue to be examined, wherein the proportion of light of different colors in the illumination light is adjustable according to the organ or tissue to be examined;
    处理器,包括拍摄元件,所述拍摄元件为光场相机,所述光场相机对来自所述光源装置的照明光照明的待检器官或组织的观察部位进行拍摄,并按时序接收不同光信号并转换为视频信号;及The processor includes a photographing component, wherein the photographing component is a light field camera, and the light field camera photographs an observation portion of an organ or tissue to be examined illuminated by illumination light from the light source device, and receives different optical signals in time series And converted to a video signal; and
    显示部,所述显示部用于接收所述处理器传输的视频信号并显示所述观察部位的图像。a display unit configured to receive a video signal transmitted by the processor and display an image of the observed portion.
  2. 如权利要求1所述的内窥镜系统,其特征在于,所述内窥镜系统还包括滤光装置,所述滤光装置用于对所述波长转换装置产生的受激光进行过滤,所述照明光中不同颜色光占比通过调节所述光源的光强度及/或调节所述波长转换装置及/或调节所述滤光装置来实现。The endoscope system according to claim 1, wherein the endoscope system further comprises a filter device for filtering a laser generated by the wavelength conversion device, The proportion of different colors of light in the illumination light is achieved by adjusting the light intensity of the light source and/or adjusting the wavelength conversion device and/or adjusting the filter device.
  3. 如权利要求1所述的内窥镜系统,其特征在于,所述光源装置还包括光源控制部,所述光源控制部调节所述光源同一脉冲区间内不同时段的电流大小从而调节所述光源的光强度。The endoscope system according to claim 1, wherein said light source device further comprises a light source control portion that adjusts a current amount of said light source at different periods in the same pulse interval to adjust said light source brightness.
  4. 如权利要求1所述的内窥镜系统,其特征在于,所述波长转换装置包括多个区域,所述区域承载或不承载波长转换材料或承载不同的波长转换材料,所述波长转换装置进一步包括调节机构,所述调节机构调节多个所述区域的面积占比以调节所述照明光中不同颜色光占比。The endoscope system according to claim 1, wherein said wavelength conversion device comprises a plurality of regions carrying or not carrying a wavelength converting material or carrying a different wavelength converting material, said wavelength converting device further An adjustment mechanism is included that adjusts an area ratio of the plurality of regions to adjust a different color ratio of light in the illumination light.
  5. 如权利要求2所述的内窥镜系统,其特征在于,所述滤光装置包括多个滤光区和调节机构,所述调节机构调节所述滤光区的面积占比以调节所述照明光中不同颜色光占比。The endoscope system according to claim 2, wherein said filter means comprises a plurality of filter zones and an adjustment mechanism, said adjustment mechanism adjusting an area ratio of said filter zones to adjust said illumination The proportion of light in different colors in the light.
  6. 如权利要求1所述的内窥镜系统,其特征在于,所述光场相机包括黑白 电荷耦合器件芯片,所述黑白电荷耦合器件芯片用于记录所述待检器官或组织不同景深的光信号。The endoscope system of claim 1 wherein said light field camera comprises black and white A charge coupled device chip for recording optical signals of different depths of field of the organ or tissue to be examined.
  7. 如权利要求1所述的内窥镜系统,其特征在于,所述处理器包括红色图像转换部、绿色图像转换部及蓝色图像转换部,所述红色图像转换部用于对每一帧图像的红色信号进行处理,并将对应的红色信号转换为所述待检器官或组织的第一表层、第一中层、第一深层信号,所述绿色图像转换部用于对每一帧图像的绿色信号进行处理,并将对应的绿色信号转换为所述待检器官或组织的第二表层、第二中层、第二深层信号,所述蓝色图像转换部用于对每一帧图像的蓝色信号进行处理,并将对应的蓝色信号转换为所述待检器官或组织的第三表层、第三中层、第三深层信号。The endoscope system according to claim 1, wherein said processor comprises a red image converting portion, a green image converting portion, and a blue image converting portion, said red image converting portion for each frame image The red signal is processed, and the corresponding red signal is converted into a first surface layer, a first middle layer, and a first deep layer signal of the organ or tissue to be examined, and the green image conversion portion is used for green of each frame image The signal is processed, and the corresponding green signal is converted into a second surface layer, a second middle layer, and a second deep layer signal of the organ or tissue to be examined, and the blue image conversion portion is used for blue of each frame image The signal is processed and the corresponding blue signal is converted to a third, third, and third deep layer signal of the organ or tissue to be examined.
  8. 如权利要求7所述的内窥镜系统,其特征在于,所述处理器进一步包括图像组合部,所述图像组合部用于将所述第一表层信号、所述第二表层信号和所述第三表层信号进行组合,以得到所述待检器官或组织的表层图像信号;将所述第一中层信号、所述第二中层信号及所述第三中层信号进行组合,以得到所述待检器官或组织的中层图像信号;以及将所述第一深层信号、所述第二深层信号及所述第三深层信号进行组合,以得到所述待检器官或组织的深层图像信号。The endoscope system according to claim 7, wherein said processor further comprises an image combining section for said first surface layer signal, said second surface layer signal, and said The third surface layer signals are combined to obtain a surface layer image signal of the organ or tissue to be inspected; the first middle layer signal, the second middle layer signal, and the third middle layer signal are combined to obtain the to-be-processed Detecting an intermediate image signal of an organ or tissue; and combining the first deep layer signal, the second deep layer signal, and the third deep layer signal to obtain a deep image signal of the organ or tissue to be examined.
  9. 如权利要求8所述的内窥镜系统,其特征在于,所述显示部包括用于显示所述待检器官或组织的表层图像的第一显示区、用于显示所述待检器官或组织的中层图像的第二显示区及用于显示所述待检器官或组织的深层图像的第三显示区。The endoscope system according to claim 8, wherein the display portion includes a first display area for displaying a superficial image of the organ or tissue to be examined, and for displaying the organ or tissue to be examined a second display area of the middle layer image and a third display area for displaying a deep image of the organ or tissue to be examined.
  10. 一种光源装置,其特征在于,所述光源装置包括发出激发光的光源,及通过所述激发光激发而产生受激光的波长转换装置,所述激发光和所述受激光形成照明光出射,所述照明光中不同颜色光的占比可调节。 A light source device, characterized in that the light source device includes a light source that emits excitation light, and a wavelength conversion device that generates laser light by excitation of the excitation light, and the excitation light and the laser light to form illumination light are emitted, The proportion of light of different colors in the illumination light can be adjusted.
PCT/CN2017/114749 2017-09-27 2017-12-06 Endoscope system and light source apparatus WO2019061819A1 (en)

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Publication number Priority date Publication date Assignee Title
WO2020221234A1 (en) * 2019-04-28 2020-11-05 北京航空航天大学 Tunable light source and endoscope system
CN110220857A (en) * 2019-06-26 2019-09-10 重庆金山医疗器械有限公司 Colored light mixing method and system, material concentration detection method and imaging of tissue method
CN112906682A (en) * 2021-02-07 2021-06-04 杭州海康慧影科技有限公司 Method and device for controlling brightness of light source and computer storage medium

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090203966A1 (en) * 2008-02-13 2009-08-13 Fujifilm Corporation Endoscope light source device
CN101610708A (en) * 2006-12-29 2009-12-23 通用检查技术公司 Illumination for endoscope
CN101617933A (en) * 2008-07-04 2010-01-06 奥林巴斯医疗株式会社 Light source device and endoscope apparatus using the same
CN102204809A (en) * 2010-03-29 2011-10-05 富士胶片株式会社 Endoscope apparatus
CN103070658A (en) * 2011-09-15 2013-05-01 富士胶片株式会社 Endoscope system and light source device
CN103793911A (en) * 2014-01-24 2014-05-14 北京科技大学 Scene depth obtaining method based on integration image technology
CN105025774A (en) * 2013-03-06 2015-11-04 奥林巴斯株式会社 Subject observation system and method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9341343B2 (en) * 2010-08-24 2016-05-17 Osram Gmbh Phosphor device and lighting apparatus comprising the same
WO2012098806A1 (en) * 2011-01-20 2012-07-26 株式会社山野光学 Lighting diaphragm
JP5451802B2 (en) * 2011-04-01 2014-03-26 富士フイルム株式会社 Electronic endoscope system and calibration method for electronic endoscope system
CN103781395B (en) * 2011-09-05 2016-04-13 富士胶片株式会社 Endoscopic system, for the treatment facility of described endoscopic system and image generating method

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101610708A (en) * 2006-12-29 2009-12-23 通用检查技术公司 Illumination for endoscope
US20090203966A1 (en) * 2008-02-13 2009-08-13 Fujifilm Corporation Endoscope light source device
CN101617933A (en) * 2008-07-04 2010-01-06 奥林巴斯医疗株式会社 Light source device and endoscope apparatus using the same
CN102204809A (en) * 2010-03-29 2011-10-05 富士胶片株式会社 Endoscope apparatus
CN103070658A (en) * 2011-09-15 2013-05-01 富士胶片株式会社 Endoscope system and light source device
CN105025774A (en) * 2013-03-06 2015-11-04 奥林巴斯株式会社 Subject observation system and method
CN103793911A (en) * 2014-01-24 2014-05-14 北京科技大学 Scene depth obtaining method based on integration image technology

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