WO2019061035A1 - 用于消毒的紫外线系统以及紫外线消毒方法 - Google Patents

用于消毒的紫外线系统以及紫外线消毒方法 Download PDF

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WO2019061035A1
WO2019061035A1 PCT/CN2017/103520 CN2017103520W WO2019061035A1 WO 2019061035 A1 WO2019061035 A1 WO 2019061035A1 CN 2017103520 W CN2017103520 W CN 2017103520W WO 2019061035 A1 WO2019061035 A1 WO 2019061035A1
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ultraviolet
light
wavelength
wavelength light
sterilization
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PCT/CN2017/103520
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English (en)
French (fr)
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何宗江
贾志强
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深圳前海小有技术有限公司
深圳市海司恩科技有限公司
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Priority to PCT/CN2017/103520 priority Critical patent/WO2019061035A1/zh
Publication of WO2019061035A1 publication Critical patent/WO2019061035A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/10—Ultraviolet radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/24—Apparatus using programmed or automatic operation

Definitions

  • the invention relates to the field of ultraviolet sterilization technology, in particular to an ultraviolet system for disinfection and a method for disinfecting ultraviolet rays.
  • UV disinfection technology is the use of ultraviolet radiation to destroy and change the DNA (deoxyribonucleic acid) structure of microorganisms, so that bacteria can die immediately or mutation can not be split, to achieve the purpose of sterilization.
  • Ultraviolet sterilization is a pure physical disinfection method. It has the advantages of simple and convenient, broad spectrum and high efficiency, no secondary pollution, easy management and automation. It is widely used in the sterilization of food, beverage, mineral water and other fields. However, in the prior art, a large number of ultraviolet lamps are used for ultraviolet sterilization. First, the ultraviolet tube has a relatively simple band, and is sterilized by 185 nm band or sterilized by 253.7 nm band.
  • Both bands have their own limitations, such as In the 253.7nm band sterilization, the biological effect is the most significant in the whole ultraviolet band, and the sterilization effect is the best, but the 253.7nm ultraviolet light only propagates along the straight line, the sterilization has a dead angle and the light resurrection phenomenon is serious; while the ultraviolet wavelength in the 185nm band is extremely short, but the photon is light. The energy level is quite high, it is easily absorbed by ozone, and ozone has a good bactericidal effect.
  • the UV lamp of ultraviolet disinfection equipment is powered by the lamp ballast. There is an insurmountable limit in technology. Therefore, the lamp tube is easy to age, the UVC output is attenuated with time, and the actin is serious. Its lamp life is short, the sterilization effect is greatly reduced, its operating cost is increased, and it cannot be instantaneously switched according to the change of the instantaneous situation.
  • the object of the present invention can be achieved by the following technical measures:
  • the present invention provides an ultraviolet system for disinfection comprising:
  • An ultraviolet irradiation device that irradiates a disinfection region with ultraviolet rays to sterilize microorganisms contained in the region, the ultraviolet irradiation device including at least two ultraviolet radiation sources;
  • a monitoring device for monitoring the dynamics of microbial activity in the area to be disinfected
  • a processing device for controlling the wavelength of ultraviolet light emitted by the ultraviolet irradiation device, the irradiation time, and the irradiation dose according to the dynamic change of the microbial activity in the region to be disinfected.
  • the ultraviolet system further comprises an environmental conditioning device for maintaining environmental conditions of the area to be disinfected Set.
  • the ultraviolet irradiation device includes a first ultraviolet radiation source for emitting first wavelength light, a second ultraviolet radiation source for emitting second wavelength light, and third ultraviolet radiation for emitting third wavelength light. source.
  • the processing device is configured to select or switch one of a plurality of selectable sterilization modes to control the switches of the different ultraviolet radiation sources respectively according to the dynamic change of the microbial activity of the area to be disinfected monitored by the monitoring device. , irradiation time and exposure dose.
  • the invention also provides an ultraviolet disinfection method comprising:
  • Sterilization step irradiating the disinfected area with ultraviolet light with a second wavelength light or a mixed light of the first wavelength light and the second wavelength light;
  • Bacteriostatic step ultraviolet irradiation of the area to be treated with the first wavelength light and/or the third wavelength light.
  • the first wavelength light is irradiated with ultraviolet rays to the disinfecting region.
  • the first wavelength light is ultraviolet light having a wavelength range of 200 nm to 250 nm
  • the second wavelength light is ultraviolet light having a wavelength range of 255 nm to 270 nm
  • the third wavelength light is ultraviolet light having a wavelength range of 275 nm to 285 nm
  • the irradiation dose of the first wavelength of light is 20mJ / cm 2 ⁇ 60mJ / cm 2
  • the irradiation dose of the second wavelength of light is 60mJ / cm 2 ⁇ 160mJ / cm 2
  • the antimicrobial step the irradiation dose of the first wavelength of light 50 mJ/cm 2 to 100 mJ/cm 2
  • the irradiation dose of the third wavelength light is 30 mJ/cm 2 to 80 mJ/cm 2 .
  • the irradiation dose of the first wavelength light is from 30 mJ/cm 2 to 80 mJ/cm 2 .
  • the environmental conditions of the area to be disinfected are kept stable during the pre-sterilization step, the sterilization step or the bacteriostatic step.
  • the microbiological detection step is further included before the pre-sterilization step:
  • the microbial activity dynamics of the area to be disinfected are monitored in real time during the pre-sterilization step, the sterilization step or the bacteriostatic step.
  • the dynamic result of the microbial activity is to initiate a bacterial sterilization mode of operation when only bacteria are present in the area to be sterilized;
  • the dynamic result of the microbial activity is a virus sterilization operation mode when the virus is present in the region to be sterilized and the fungus spores and/or spores are not present;
  • the dynamic result of the microbial activity is a spore/spore sterilization mode of operation when the fungus spores and/or spores are present in the area to be sterilized.
  • the ultraviolet system of the present invention has at least two sources of ultraviolet radiation, which cooperate with each other to ensure complete destruction of the microbial DNA and reduce the possibility of photorepair and dark repair, thereby improving the sterilization effect.
  • FIG. 1 is a block diagram showing the structure of an ultraviolet system according to an embodiment of the present invention.
  • Fig. 2 is a timing chart of the ultraviolet disinfection method of the embodiment of the present invention.
  • an embodiment of the present invention provides an ultraviolet system 100 for disinfection.
  • the ultraviolet system 100 includes: an ultraviolet irradiation device 10 , a monitoring device 20 , a processing device 30 , and an environment adjusting device 40 .
  • the irradiation device 10 irradiates the disinfection area with ultraviolet rays to sterilize the microorganisms contained in the area, the ultraviolet irradiation device 10 includes at least two ultraviolet radiation sources, and the monitoring device 20 is configured to monitor the dynamics of the microorganism activity in the area to be disinfected; 30 is used for controlling the ultraviolet light wavelength, the irradiation time and the irradiation dose emitted by the ultraviolet irradiation device 10 according to the dynamic change of the microbial activity in the area to be disinfected; the environmental adjustment device 40 is for maintaining the environmental condition of the area to be disinfected.
  • the ultraviolet irradiation device 10 includes a first ultraviolet radiation source for emitting light of a first wavelength and is used for a second ultraviolet radiation source that emits light of a second wavelength; in a second preferred embodiment, the ultraviolet irradiation device 10 includes a second ultraviolet radiation source for emitting light of the second wavelength and a third ultraviolet light for emitting the third wavelength light a source of ultraviolet radiation; in a third preferred embodiment, the ultraviolet irradiation device 10 includes a first ultraviolet radiation source for emitting light of a first wavelength, a second ultraviolet radiation source for emitting light of a second wavelength, and for exiting a third ultraviolet radiation source of the third wavelength light; wherein the first wavelength light is ultraviolet light having a wavelength range of 200 nm to 250 nm, the second wavelength light is ultraviolet light having a wavelength range of 255 nm to 270 nm, and the third wavelength light is a wavelength range of 275
  • the processing device 30 is configured to select or switch one of a plurality of selectable sterilization modes to control different ultraviolet radiation sources, respectively, based on dynamic changes in microbial activity of the region to be disinfected monitored by the monitoring device 20. Switch, irradiation time and dose.
  • the ultraviolet system 100 for disinfection of the embodiment of the present invention is configured with three sterilization operation modes, a bacterial sterilization operation mode, a virus sterilization operation mode, and a spore/spore sterilization operation mode. In the above three different sterilization operation modes, the opening sequence and the irradiation dose of at least two ultraviolet radiation sources in the ultraviolet irradiation device 10 are different.
  • the monitoring device 20 can monitor the dynamics of the microbial activity of the entire area to be disinfected before the ultraviolet radiation source is turned on, and the processing device 30 initiates the bacterial sterilization operation mode when the microbial activity dynamic result is that only bacteria are present in the area to be disinfected;
  • the treatment device 30 initiates a virus sterilization mode of operation when the microbial activity dynamic result is that there is a virus in the area to be disinfected and no fungal spores and/or spores are present; the treatment device 30 has a fungus in the microbe activity dynamic result in the area to be disinfected In the case of spores and/or spores, the spore/spore sterilization mode of operation is initiated.
  • the monitoring device 20 can also continuously monitor the dynamics of the microbial activity of the entire area to be disinfected during the entire ultraviolet disinfection process. Once the dynamic result of the microbial activity changes, the current sterilization mode is immediately stopped, and the switching is compatible with the dynamic result of the microbial activity. The sterilization mode is equipped.
  • the biological activity dynamics monitored by the monitoring device 20 may include the presence of microorganisms, the number (concentration) of microorganisms, the type of microorganisms, etc., for example, the presence or absence of bacteria, the presence or absence of a virus, the presence or absence of fungal spores, whether
  • the monitoring device 20 may include one or more of a biosensor or a chemical sensor or a mechanical sensor or a monitoring device (eg, a camera, a camera, etc.), in the presence of a spore-forming fungus, a total number of microorganisms, a number of microorganisms of each type, and the like.
  • a biosensor has one or more molecular probes built therein, and one or more molecular probes are configured to cooperate with at least one target, which may be an enzyme, an antibody, an antigen, a microorganism, a cell, a tissue, or a nucleic acid.
  • target which may be an enzyme, an antibody, an antigen, a microorganism, a cell, a tissue, or a nucleic acid.
  • a biologically active substance for capturing data of one or more chemical quantities emitted by biological activity, for example, a chemical sensor for detecting a gas produced by one or more metabolic processes of a microorganism; a mechanical sensor for obtaining a disinfection to be disinfected
  • mechanical sensors can include piezoelectric sensing , Various films, cantilever, micro-electromechanical sensor, or MEMS, nanotechnological mechanical sensor; Further, since the ultraviolet light fluoresces microorganisms may be observed directly from the monitoring device.
  • the environment adjusting device 40 can adjust the environmental conditions such as temperature, humidity, and airflow of the disinfection area, and maintain the environmental conditions of the area to be disinfected stably, which is beneficial to better achieve bacteriostasis.
  • the ultraviolet system 100 described above also includes a power supply unit that supplies power to various components and devices to provide power.
  • the power supply unit can be a battery or a power supply obtained by converting the utility power through an adapter.
  • an embodiment of the present invention further provides a method for applying ultraviolet disinfection of the ultraviolet system 100 for disinfection described above, comprising:
  • Pre-sterilization step ultraviolet irradiation of the disinfecting area with the first wavelength light.
  • Sterilization step using a second wavelength light or a mixed light of the first wavelength light and the second wavelength light to perform a purple treatment on the disinfected area External exposure;
  • Bacteriostatic step ultraviolet irradiation of the area to be treated with the first wavelength light and/or the third wavelength light.
  • the first wavelength light is ultraviolet light having a wavelength range of 200 nm to 250 nm
  • the second wavelength light is ultraviolet light having a wavelength range of 255 nm to 270 nm
  • the third wavelength light is ultraviolet light having a wavelength range of 275 nm to 285 nm
  • the irradiation dose of the first wavelength light is 30 mJ/cm 2 to 80 mJ/cm 2
  • the sterilization step the irradiation dose of the first wavelength light is 20 mJ/cm 2 to 60 mJ/cm 2
  • the irradiation dose of the second wavelength light is 60 mJ.
  • the irradiation dose of the first wavelength light is 50 mJ/cm 2 to 100 mJ/cm 2
  • the irradiation dose of the third wavelength light is 30 mJ/cm 2 to 80 mJ/cm 2 .
  • the second wavelength light may be used alone, or the first wavelength light and the second wavelength light may be used simultaneously; in the inhibition step, the first wavelength light may be used alone, and the third wavelength light may be used alone. It is also possible to use both the first wavelength light and the third wavelength light.
  • the first wavelength light and the third wavelength light are alternately operated, as shown in FIG. 2, in a preferred embodiment, One ultraviolet radiation source is UVLED1, the second ultraviolet radiation source is UVLED2, and the third ultraviolet radiation source is UVLED3.
  • the photoremediation enzyme of the microorganism is destroyed; in the sterilization step, the DNA of the microorganism is destroyed; in the inhibition step, the dark repair is suppressed.
  • the microbial DNA is completely destroyed and the repair possibility is reduced, the sterilization effect is improved, and a 5 log sterilization effect can be achieved.
  • the microbial activity dynamics of the disinfection zone can be detected prior to the pre-sterilization step, and the sterilization process can be initiated according to the test results in accordance with the corresponding sterilization mode. It is also possible to monitor the microbial activity dynamics of the area to be disinfected in real time during the pre-sterilization step, the sterilization step or the bacteriostatic step, and switch the sterilization mode at any time according to the change of the monitoring result.
  • the dynamic result of the microbial activity is to initiate a bacterial sterilization operation mode when only bacteria are present in the region to be sterilized; the dynamic result of the microbial activity is that there is a virus in the region to be sterilized and no fungal spores and/or spores are present.
  • a virus sterilization operation mode is initiated; when the microbial activity dynamic result is a fungus having a fungal spore and/or spore state in the region to be sterilized, the spore/spore sterilization operation mode is initiated.
  • the ultraviolet disinfection method of the embodiment of the present invention in the bacterial sterilization operation mode, in the pre-sterilization step, the irradiation dose of the first wavelength light is 30 mJ/cm 2 to 50 mJ/cm 2 ; in the sterilization step, the first wavelength The irradiation dose of light is 20 mJ/cm 2 to 30 mJ/cm 2 , and the irradiation dose of the second wavelength light is 60 mJ/cm 2 to 80 mJ/cm 2 ; in the bacteriostatic step, the irradiation dose of the first wavelength light is 50 mJ/cm.
  • the irradiation dose of the first wavelength light is 40 mJ/cm 2 to 60 mJ/cm 2 ; in the sterilization step, the irradiation dose of the first wavelength light is 20 mJ/cm 2 ⁇ 50 mJ/cm 2 , the irradiation dose of the second wavelength light is 60 mJ/cm 2 to 100 mJ/cm 2 ; in the bacteriostatic step, the irradiation dose of the first wavelength light is 60 mJ/cm 2 to 80 mJ/cm 2 , the third wavelength The irradiation dose of light is 40 mJ/cm 2 to 60 mJ/cm 2 .
  • the irradiation dose of the first wavelength light is 60 mJ/cm 2 to 80 mJ/cm 2 ; in the sterilization step, the irradiation dose of the first wavelength light is 40 mJ/cm 2 ⁇ 60mJ / cm 2, the irradiation dose of the second wavelength of light is 100mJ / cm 2 ⁇ 160mJ / cm 2; in the antimicrobial step, the first wavelength light irradiation dose of 80mJ / cm 2 ⁇ 100mJ / cm 2, the third The irradiation dose of the wavelength light is 60 mJ/cm 2 to 80 mJ/cm 2 .

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  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

一种用于消毒的紫外线系统（100）以及紫外线消毒方法，该紫外线系统（100）包括：紫外线照射装置（10）、监测装置（20）、处理装置（30）和环境调节装置（40）。该紫外线系统（100）具有至少两个紫外辐射源，二者相互配合，保证微生物DNA被完全破坏且降低光修复和暗修复的可能性，提高灭菌效果。

Description

用于消毒的紫外线系统以及紫外线消毒方法 技术领域
本发明涉及紫外灭菌技术领域，具体涉及一种用于消毒的紫外线系统以及紫外线消毒方法。
背景技术
紫外线消毒杀菌技术，就是利用紫外线的照射，破坏及改变微生物的DNA(脱氧核糖核酸)结构，使细菌当即死亡或发生突变不能分裂，达到杀菌的目的。紫外线杀菌属于纯物理消毒方法，具有简单便捷、广谱高效，无二次污染、便于管理和实现自动化等优点，因而被广泛用于食品、饮料、矿泉水等领域杀菌消毒。但是现有技术中大量用于紫外线杀菌消毒的为紫外灯管，首先，紫外灯管波段比较单一，有用185nm波段杀菌或用253.7nm波段杀菌，这两种波段杀菌都有自己的局限性，比如253.7nm波段杀菌，其在整个紫外波段中生物效应最为显著，杀菌效果最好，但是253.7nm紫外线只沿直线传播，杀菌有死角且光复活现象严重；而185nm波段的紫外线波长极短，但是光量子能级相当高，很容易被臭氧吸收，而臭氧也有很好的杀菌作用。其次，紫外线杀菌设备的紫外灯管其动力来源于灯管镇流器，技术上存在着不可逾越的极限，因此其灯管容易老化，UVC输出随时间的推移而衰减，光化作用严重，使其灯管寿命短，杀菌效果大打折扣，使其运行成本增加，并且不能根据瞬间情况的变化瞬时开关。
鉴于此，克服以上现有技术中的缺陷，提供一种新的用于消毒的紫外线系统成为本领域亟待解决的技术问题。
发明内容
本发明的目的在于针对现有技术的上述缺陷，提供一种用于消毒的紫外线系统。
本发明的目的可通过以下的技术措施来实现：
本发明提供了一种用于消毒的紫外线系统，包括：
对待消毒区域进行紫外线照射以对区域中含有的微生物进行灭菌的紫外线照射装置，所述紫外线照射装置包括至少两个紫外辐射源；
用于监测所述待消毒区域的微生物活性动态的监测装置；以及
用于根据待消毒区域的微生物活性动态变化对所述紫外线照射装置所出射紫外光波长、照射时间及照射剂量进行控制的处理装置。
优选地，该紫外线系统还包括用于将待消毒区域的环境条件保持稳定的环境调节装 置。
优选地，所述紫外线照射装置包括用于出射第一波长光的第一紫外辐射源、用于出射第二波长光的第二紫外辐射源、和用于出射第三波长光的第三紫外辐射源。
优选地，所述处理装置被配置为用于根据监测装置所监测待消毒区域的微生物活性动态变化从多个可选择的灭菌操作模式中选择或切换其中一个以分别控制不同紫外辐射源的开关、照射时间和照射剂量。
本发明还提供了一种紫外线消毒方法，包括：
杀菌步骤：用第二波长光或第一波长光和第二波长光的混合光对待消毒区域进行紫外线照射；和
抑菌步骤：用第一波长光和/或第三波长光对待消毒区域进行紫外线照射。
优选地，在杀菌步骤之前还包括预杀菌步骤：用第一波长光对待消毒区域进行紫外线照射。
优选地，第一波长光为波长范围200nm～250nm的紫外光，第二波长光为波长范围255nm～270nm的紫外光，第三波长光为波长范围275nm～285nm的紫外光；在杀菌步骤中，第一波长光的照射剂量为20mJ/cm2～60mJ/cm2，第二波长光的照射剂量为60mJ/cm2～160mJ/cm2；在抑菌步骤中，第一波长光的照射剂量为50mJ/cm2～100mJ/cm2，第三波长光的照射剂量为30mJ/cm2～80mJ/cm2。
优选地，在预杀菌步骤中，第一波长光的照射剂量为30mJ/cm2～80mJ/cm2。
优选地，在预杀菌步骤、杀菌步骤或抑菌步骤中，将待消毒区域的环境条件保持稳定。
优选地，在所述预杀菌步骤之前还包括微生物检测步骤：
对待消毒区域的微生物活性动态进行检测。
优选地，在预杀菌步骤、杀菌步骤或抑菌步骤中，对待消毒区域的微生物活性动态进行实时监测。
优选地，所述微生物活性动态结果为待灭菌区域仅存在细菌时，启动细菌灭菌操作模式；
所述微生物活性动态结果为待灭菌区域存在病毒且不存在真菌孢子和/或芽孢状态的菌类时，启动病毒灭菌操作模式；
所述微生物活性动态结果为待灭菌区域存在真菌孢子和/或芽孢状态的菌类时，启动孢子/芽孢灭菌操作模式。
本发明的紫外线系统具有至少两个紫外辐射源，二者相互配合，保证微生物DNA被完全破坏且降低光修复和暗修复的可能性，提高灭菌效果。
附图说明
图1是本发明实施例的紫外线系统的结构框图。
图2是本发明实施例的紫外线消毒方法的时序图。
具体实施方式
为了使本发明的目的、技术方案及优点更加清楚明白，下面结合附图和具体实施例对本发明作进一步详细说明。应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。
为了使本揭示内容的叙述更加详尽与完备，下文针对本发明的实施方式与具体实施例提出了说明性的描述；但这并非实施或运用本发明具体实施例的唯一形式。实施方式中涵盖了多个具体实施例的特征以及用以建构与操作这些具体实施例的方法步骤与其顺序。然而，亦可利用其它具体实施例来达成相同或均等的功能与步骤顺序。
请参阅图1所示，本发明实施例提供了一种用于消毒的紫外线系统100，该紫外线系统100包括：紫外线照射装置10、监测装置20、处理装置30和环境调节装置40，其中，紫外线照射装置10对待消毒区域进行紫外线照射以对区域中含有的微生物进行灭菌，紫外线照射装置10包括至少两个紫外辐射源；监测装置20用于监测所述待消毒区域的微生物活性动态；处理装置30用于根据待消毒区域的微生物活性动态变化对紫外线照射装置10所出射紫外光波长、照射时间及照射剂量进行控制；环境调节装置40用于将待消毒区域的环境条件保持稳定。
具体地，对于紫外线照射装置10中的至少两个紫外辐射源的配置方式，在第一个优选实施方式中，紫外线照射装置10包括用于出射第一波长光的第一紫外辐射源和用于出射第二波长光的第二紫外辐射源；在第二个优选实施方式中，紫外线照射装置10包括用于出射第二波长光的第二紫外辐射源和用于出射第三波长光的第三紫外辐射源；在第三个优选实施方式中，紫外线照射装置10包括用于出射第一波长光的第一紫外辐射源、用于出射第二波长光的第二紫外辐射源、和用于出射第三波长光的第三紫外辐射源；其中，第一波长光为波长范围200nm～250nm的紫外光，第二波长光为波长范围255nm～270nm的紫外光，第三波长光为波长范围275nm～285nm的紫外光。
具体地，处理装置30被配置为用于根据监测装置20所监测待消毒区域的微生物活性动态变化从多个可选择的灭菌操作模式中选择或切换其中一个以分别控制不同紫外辐射源 的开关、照射时间和照射剂量。例如，本发明实施例的用于消毒的紫外线系统100配置有三种灭菌操作模式，分别为细菌灭菌操作模式、病毒灭菌操作模式以及孢子/芽孢灭菌操作模式。在上述三种不同的灭菌操作模式中，紫外线照射装置10中的至少两个紫外线辐射源的开启顺序、照射剂量不同。
具体地，监测装置20可以在紫外线辐射源开启之前先对整个待消毒区域的微生物活性动态进行监测，处理装置30在微生物活性动态结果为待消毒区域仅存在细菌时，启动细菌灭菌操作模式；处理装置30在微生物活性动态结果为待消毒区域存在病毒且不存在真菌孢子和/或芽孢状态的菌类时，启动病毒灭菌操作模式；处理装置30在微生物活性动态结果为待消毒区域存在真菌孢子和/或芽孢状态的菌类时，启动孢子/芽孢灭菌操作模式。监测装置20也可以在整个紫外线消毒的过程中持续对整个待消毒区域的微生物活性动态进行监测，一旦微生物活性动态结果发生变化，立即停止当前灭菌模式的运行，切换与微生物活性动态结果相适配的灭菌模式。在一个优选实施方式中，监测装置20所监测的生物活性动态可以包括微生物的存在、微生物的数量(浓度)、微生物的类型等，例如，是否存在细菌、是否存在病毒、是否存在真菌孢子、是否存在芽孢状态的菌类、微生物的总数量、各类型微生物的数量等，监测装置20可以包括生物传感器或化学传感器或机械传感器或监视设备(例如相机、摄像机等)中的一种或多种，例如，生物传感器内置有一个或多个分子探针，一个或多个分子探针被构造为与至少一个靶标相配合，分子探针可以是酶、抗体、抗原、微生物、细胞、组织或核酸等生物活性物质；化学传感器用于捕捉由生物活性发射的一个或多个化学量的数据，例如，化学传感器用于检测一种或多种微生物代谢过程中产生的气体；机械传感器用于获得待消毒区域的其他数据，机械传感器可以包括压电传感器、各种膜、悬臂、微机电传感器或者MEMS、纳米机械传感器；另外，由于微生物在紫外光中发出荧光，从监视设备中可以直接观察到。
具体地，环境调节装置40可以对待消毒区域的温度、湿度以及气流等环境条件进行调节，保持待消毒区域的环境条件稳定，有利于更好地实现抑菌。
上述紫外线系统100还包括电源装置，电源装置给各个部件和装置供电，提供电力。电源装置可以是电池，也可以市电经过适配器转换获得的供电。
相应地，本发明实施例还提供了一种应用上述的用于消毒的紫外线系统100进行紫外线消毒的方法，包括：
预杀菌步骤：用第一波长光对待消毒区域进行紫外线照射。
杀菌步骤：用第二波长光或第一波长光和第二波长光的混合光对待消毒区域进行紫 外线照射；和
抑菌步骤：用第一波长光和/或第三波长光对待消毒区域进行紫外线照射。
其中，第一波长光为波长范围200nm～250nm的紫外光，第二波长光为波长范围255nm～270nm的紫外光，第三波长光为波长范围275nm～285nm的紫外光；在预杀菌步骤中，第一波长光的照射剂量为30mJ/cm2～80mJ/cm2；在杀菌步骤中，第一波长光的照射剂量为20mJ/cm2～60mJ/cm2，第二波长光的照射剂量为60mJ/cm2～160mJ/cm2；在抑菌步骤中，第一波长光的照射剂量为50mJ/cm2～100mJ/cm2，第三波长光的照射剂量为30mJ/cm2～80mJ/cm2。
其中，在杀菌步骤中，可以单独使用第二波长光，也可以同时使用第一波长光和第二波长光；在抑菌步骤中，可以单独使用第一波长光，可以单独使用第三波长光，也可以同时使用第一波长光和第三波长光。在抑菌步骤中，同时使用第一波长光和第三波长光时，进一步地，第一波长光和第三波长光二者交替运行，请参见图2所示，在一个优选实施方式中，第一紫外辐射源为UVLED1，第二紫外辐射源为UVLED2，第三紫外辐射源为UVLED3。
在预杀菌步骤中，微生物的光修复酶被破坏；在杀菌步骤中，微生物的DNA被破坏；在抑菌步骤中，抑制暗修复。通过第一波长光、第二波长光和第二波长光的配合，保证微生物DNA被完全破坏且降低修复可能性，提高了灭菌效果，能够实现5log的灭菌效果。[0033]其中，在预杀菌步骤、杀菌步骤或抑菌步骤中，将待消毒区域的环境条件保持稳定。尤其是在抑菌步骤中，进行降低温度或者禁止气体交换，减少细菌繁殖以及拒绝引入新的细菌，有利于更好实现抑菌的功能。
另外，可以在预杀菌步骤之前对待消毒区域的微生物活性动态进行检测，再根据检测结果按照对应的灭菌操作模式启动灭菌程序。也可以在预杀菌步骤、杀菌步骤或抑菌步骤中，对待消毒区域的微生物活性动态进行实时监测，根据监测结果的变化随时切换灭菌模式。具体地，所述微生物活性动态结果为待灭菌区域仅存在细菌时，启动细菌灭菌操作模式；所述微生物活性动态结果为待灭菌区域存在病毒且不存在真菌孢子和/或芽孢状态的菌类时，启动病毒灭菌操作模式；所述微生物活性动态结果为待灭菌区域存在真菌孢子和/或芽孢状态的菌类时，启动孢子/芽孢灭菌操作模式。
本发明实施例的紫外线消毒的方法，在细菌灭菌操作模式下，在预杀菌步骤中，第一波长光的照射剂量为30mJ/cm2～50mJ/cm2；在杀菌步骤中，第一波长光的照射剂量为20mJ/cm2～30mJ/cm2，第二波长光的照射剂量为60mJ/cm2～80mJ/cm2；在抑菌步骤中，第 一波长光的照射剂量为50mJ/cm2～60mJ/cm2，第三波长光的照射剂量为30mJ/cm2～50mJ/cm2。在病毒灭菌操作模式下，在预杀菌步骤中，第一波长光的照射剂量为40mJ/cm2～60mJ/cm2；在杀菌步骤中，第一波长光的照射剂量为20mJ/cm2～50mJ/cm2，第二波长光的照射剂量为60mJ/cm2～100mJ/cm2；在抑菌步骤中，第一波长光的照射剂量为60mJ/cm2～80mJ/cm2，第三波长光的照射剂量为40mJ/cm2～60mJ/cm2。在孢子/芽孢灭菌操作模式下，在预杀菌步骤中，第一波长光的照射剂量为60mJ/cm2～80mJ/cm2；在杀菌步骤中，第一波长光的照射剂量40mJ/cm2～60mJ/cm2，第二波长光的照射剂量为100mJ/cm2～160mJ/cm2；在抑菌步骤中，第一波长光的照射剂量为80mJ/cm2～100mJ/cm2，第三波长光的照射剂量为60mJ/cm2～80mJ/cm2。
以上所述仅为本发明的较佳实施例而已，并不用以限制本发明，凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等，均应包含在本发明的保护范围之内。

Claims (12)

  1. 一种用于消毒的紫外线系统，其特征在于，该紫外线系统包括：
    对待消毒区域进行紫外线照射以对区域中含有的微生物进行灭菌的紫外线照射装置，所述紫外线照射装置包括至少两个紫外辐射源；
    用于监测所述待消毒区域的微生物活性动态的监测装置；以及
    用于根据待消毒区域的微生物活性动态变化对所述紫外线照射装置所出射紫外光波长、照射时间及照射剂量进行控制的处理装置。
  2. 根据权利要求1所述的用于消毒的紫外线系统，其特征在于，该紫外线系统还包括用于将待消毒区域的环境条件保持稳定的环境调节装置。
  3. 根据权利要求1所述的用于消毒的紫外线系统，其特征在于，所述紫外线照射装置包括用于出射第一波长光的第一紫外辐射源、用于出射第二波长光的第二紫外辐射源、和用于出射第三波长光的第三紫外辐射源。
  4. 根据权利要求1所述的用于消毒的紫外线系统，其特征在于，所述处理装置被配置为用于根据监测装置所监测待消毒区域的微生物活性动态变化从多个可选择的灭菌操作模式中选择或切换其中一个以分别控制不同紫外辐射源的开关、照射时间和照射剂量。
  5. 一种紫外线消毒方法，其特征在于，该方法包括：
    杀菌步骤：用第二波长光或第一波长光和第二波长光的混合光对待消毒区域进行紫外线照射；和
    抑菌步骤：用第一波长光和/或第三波长光对待消毒区域进行紫外线照射。
  6. 根据权利要求5所述的紫外线消毒方法，其特征在于，在杀菌步骤之前还包括预杀菌步骤：用第一波长光对待消毒区域进行紫外线照射。
  7. 根据权利要求5或6所述的紫外线消毒方法，其特征在于，第一波长光为波长范围200nm～250nm的紫外光，第二波长光为波长范围255nm～270nm的紫外光，第三波长光为波长范围275nm～285nm的紫外光；在杀菌步骤中，第一波长光的照射剂量为20mJ/cm2～60mJ/cm2，第二波长光的照射剂量为60mJ/cm2～160mJ/cm2；在抑菌步骤中，第一波长光的照射剂量为50mJ/cm2～100mJ/cm2，第三波长光的照射剂量为30mJ/cm2～80mJ/cm2。
  8. 根据权利要求7所述的紫外线消毒方法，其特征在于，在预杀菌步骤中，第一波长光的照射剂量为30mJ/cm2～80mJ/cm2。
  9. 根据权利要求5或6所述的紫外线消毒方法，其特征在于，在预杀菌步骤、杀菌步骤或抑菌步骤中，将待消毒区域的环境条件保持稳定。
  10. 根据权利要求5或6所述的紫外线消毒方法，其特征在于，在所述预杀菌步骤之前还包 括微生物检测步骤：
    对待消毒区域的微生物活性动态进行检测。
  11. 根据权利要求5或6所述的紫外线消毒方法，其特征在于，在预杀菌步骤、杀菌步骤或抑菌步骤中，对待消毒区域的微生物活性动态进行实时监测。
  12. 根据权利要求10或11所述的紫外线消毒方法，其特征在于，所述微生物活性动态结果为待灭菌区域仅存在细菌时，启动细菌灭菌操作模式；
    所述微生物活性动态结果为待灭菌区域存在病毒且不存在真菌孢子和/或芽孢状态的菌类时，启动病毒灭菌操作模式；
    所述微生物活性动态结果为待灭菌区域存在真菌孢子和/或芽孢状态的菌类时，启动孢子/芽孢灭菌操作模式。
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