WO2019042302A1

WO2019042302A1 - Covered stent and preparation method therefor

Info

Publication number: WO2019042302A1
Application number: PCT/CN2018/102827
Authority: WO
Inventors: 肖本好; 王逸斐
Original assignee: 先健科技(深圳)有限公司
Priority date: 2017-08-30
Filing date: 2018-08-29
Publication date: 2019-03-07
Also published as: CN109419570A

Abstract

The present invention relates to a covered stent and a preparation method therefor. The covered stent comprises a stent body and a covering membrane. The stent body has a first surface and a second surface opposite the first surface. The covering membrane comprises a first membrane and a second membrane. The first membrane is arranged on the first surface. The second membrane is arranged on the second surface and is bonded with the first membrane. The covering membrane further comprises a connector fixedly connected to the stent body. The connector is located between the first membrane and the second membrane. The connector is bonded with at least one of the first membrane and the second membrane. The covered stent can improve the connection strength between the covering membrane and the stent body.

Description

Covered stent and preparation method thereof

Technical field

The invention relates to the field of medical instruments, in particular to a stent graft and a preparation method thereof.

Background technique

The existing endoluminal graft stent is divided into a bare stent composed of a metal stent and a stent graft composed of a coating material and a metal stent according to the structural morphological type, wherein the stent graft adopts a leak-proof coating material to carry out the stent. The wrapper, when it is released at the lesion site, acts as a barrier to blood flow.

The stent graft generally covers the metal stent by heat treatment and suturing the single layer or multiple layers of the coating material. A conventional stent graft using a polyethylene terephthalate (PET) film is generally fixed to one or both sides of the metal stent by stitching. Referring to FIG. 1 to FIG. 3, when the film 240 made of expanded polytetrafluoroethylene (ePTFE) is used, the film 240 has a high elongation and is easily deformed, and is not suitable for the metal stent 210 by a stitching process. The ePTFE is melted at a high temperature (for example, 327 ° C), and the films are bonded to each other after cooling. The inner membrane 241 of ePTFE and the outer membrane 243 of ePTFE are completely or partially wrapped with the metal stent 210, and heat-treated. The portions in contact with the inner and outer films are bonded together to fix the metal bracket 210 between the inner film 241 and the outer film 243.

Referring to FIG. 4 to FIG. 6 , there is no adhesive between the ePTFE material itself and the metal bracket 210 , and there is still a certain gap 260 when the inner film 241 and the outer film 243 meet the metal wire of the metal bracket 210 , resulting in a stent graft. Under the action of an external force, the metal stent 210 is liable to loosen between the inner membrane 241 and the outer membrane 243, and a tearing force is generated on the contact surface where the inner membrane 241 and the outer membrane 243 are bonded. The lower inner membrane 241 and the outer membrane 243 are gradually separated because the ePTFE loses viscosity at normal temperature, so the separation is irreversible, and the inner membrane 241 and the outer membrane 243 may be partially detached, and even the metal stent may be detached from the coating 240. The risk of failure.

Summary of the invention

Based on this, it is necessary to provide a stent graft capable of improving the joint strength between the membrane and the stent and a preparation method thereof.

A stent graft comprising a stent body and a coating, the stent having a first surface and a second surface opposite the first surface, the coating comprising a first membrane and a second membrane, a first diaphragm is disposed on the first surface, the second diaphragm is disposed on the second surface and bonded to the first diaphragm, and the coating further includes a fixed body attached to the bracket body a connector, the connector being located between the first diaphragm and the second diaphragm, the connector being bonded to at least one of the first diaphragm and the second diaphragm.

In the above-mentioned film-covered stent, under the action of an external force, the stent body is fixed to one of the first membrane and the second membrane by the connecting member, so that it is not easy to be in the first membrane and the second membrane. Loosening occurs, which increases the connection strength between the film and the stent body, and reduces the risk of failure of the stent graft caused by the displacement of the stent body when the stent is stressed or deformed.

In one embodiment, the connector is an envelope encasing the stent body.

In one embodiment, the ratio of the sum of the thicknesses of the first diaphragm and the second diaphragm to the thickness of the envelope is 4:1 to 20:1.

In one embodiment, the stent body includes a wave ring including a crest, a trough, and a side bar, the side bar connecting the crests and troughs, the crests and the envelope of the trough surface The thickness is less than the thickness of the envelope of the side bar surface.

In one embodiment, at least one of the first surface and the second surface is recessed inwardly to form a groove, and the connecting member is received in and fixed to the groove.

In one embodiment, the material of the connector is the same as the material of the first diaphragm and/or the second diaphragm.

The preparation method of the above-mentioned stent graft comprises the following steps:

Forming a connector covering the bracket body on the bracket body; and

The first diaphragm is disposed on the first surface of the bracket body, and the second diaphragm is disposed on the second surface of the bracket body, the first diaphragm and the second diaphragm The first film, the second film, and the connecting member are bonded and fixed by heat treatment.

In one embodiment, the step of forming a connector covering the stent body on the stent body is specifically: winding the connector around the stent body to form a coating covering the stent body.

In one embodiment, the step of forming a connector covering the bracket body on the bracket body is specifically: forming a coating on the surface of the bracket body to obtain the connector.

Another preparation method of the above-mentioned stent graft includes the following steps:

Providing the bracket body, at least one of the first surface and the second surface of the bracket body is recessed inward to form a groove;

The first diaphragm is disposed on the first surface of the bracket body, and the second diaphragm is disposed on the second surface of the bracket body, the first diaphragm and the second diaphragm Performing a heat treatment to bond the first film to the second film, and at least one of the first film and the second film is filled with the groove after heat treatment to be received and fixed to the concave The connector of the slot.

DRAWINGS

1 is a schematic structural view of a conventional stent graft;

2 is a partial structural schematic view of the stent graft shown in FIG. 1;

Figure 3 is a partial cross-sectional view of the stent graft of Figure 2;

Figure 4 is a partial enlarged view of Figure 3;

Figure 5 is a schematic view showing the structure of the stent graft of Figure 3 in a state of use;

Figure 6 is a schematic view showing the structure of the stent graft of Figure 3 in another state of use;

Figure 7 is a partial cross-sectional view showing a stent graft of an embodiment;

Figure 8 is a schematic structural view of a wave ring of the stent graft of Figure 7;

Figure 9 is a partial enlarged view of the wave ring of Figure 8;

Figure 10 is a partial enlarged view of the side bar of the wave ring of Figure 8;

Figure 11 is a cross-sectional view of the side bar of Figure 10;

Figure 12 is a partial enlarged view of the stent graft of Figure 7;

Figure 13 is a partial cross-sectional view showing a stent graft of another embodiment;

Figure 14 is a schematic view showing the structure of the stent body of the stent graft of Figure 13;

15 is a schematic structural view of a stent graft according to still another embodiment.

Figure 16 is a schematic view showing the structure of the coil of the stent graft of Figure 15;

Figure 17 is a cross-sectional view of the wave coil of Figure 16;

Figure 18 is a schematic view showing the structure of the coil and the connecting member of the stent graft of Figure 15;

Detailed ways

In order to facilitate the understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. Preferred embodiments of the invention are shown in the drawings. However, the invention may be embodied in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that the understanding of the present disclosure will be more fully understood.

It should be noted that when an element is referred to as being "fixed" to another element, it can be directly on the other element or the element can be present. When an element is considered to be "connected" to another element, it can be directly connected to the other element or. The terms "vertical," "horizontal," "left," "right," "upper," "lower," "far," "near," and the like, as used herein, are for illustrative purposes only.

All technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, unless otherwise defined. The terminology used in the description of the present invention is for the purpose of describing particular embodiments and is not intended to limit the invention. The term "and/or" used herein includes any and all combinations of one or more of the associated listed items.

Referring to FIGS. 7 and 8 , the stent graft 300 of one embodiment includes a stent body 310 and a coating 340 .

The bracket body 310 includes a wave ring 312. The wave ring 312 is an alloy wire braided wave ring or a cut metal wave ring. In the illustrated embodiment, the coil 312 is woven from a titanium-nickel alloy wire. The cross section of the wave ring 312 is circular.

In one of the embodiments, the bracket body 310 is substantially cylindrical, and the plurality of coils 312 are spaced apart in the axial direction of the bracket body 310. Of course, in other embodiments, the structure of the bracket body 310 is not limited thereto. For example, the bracket body 310 further includes a connecting rod (not shown) connected between the adjacent two coils 312. The two adjacent coils 312 are connected by at least one connecting rod. The spacing between the turns 312 is equal. Of course, the spacing between the turns 312 may also be unequal.

In the illustrated embodiment, the coil 312 is a Z-shaped coil. The wave circle 312 includes a peak 3121, a trough 3123, and a side bar 3125. The side bars 3125 connect adjacent peaks 3123 and troughs 3125.

The bracket body 310 has a first surface and a second surface opposite the first surface. In the illustrated embodiment, the first surface refers to the outer surface of the stent body 310 and the second surface refers to the inner surface of the stent body 310.

The film 340 includes a first diaphragm 341, a second diaphragm 343, and a connector 345. The material of the film 340 is expanded polytetrafluoroethylene. Preferably, the materials of the first diaphragm 341, the second diaphragm 343 and the connecting member 345 are the same material, which facilitates the hot melt bonding of the coating 340. Of course, in other embodiments, the materials of the first diaphragm 341, the second diaphragm 343, and the connecting member 345 can be fused and bonded to each other with a similar melting point. It can be understood that the connecting member 345 can also be an envelope formed by an adhesive coated on the bracket body 310 to increase the bonding strength of the bracket body 310 and the coating film 340. For example, the material of the connector 345 is polyperfluoroethylene propylene (FEP).

The first diaphragm 341 is disposed on the first surface of the bracket body 310, and the second diaphragm 343 is disposed on the second surface of the bracket body 310, thereby clamping the bracket body 310 and the connecting member 345 to the first diaphragm 341 and the second Between the diaphragms 343. In the illustrated embodiment, the first diaphragm 341 and the second diaphragm 343 have the same thickness.

Referring also to FIG. 9 , the connector 345 is a wrap that wraps the coil 312 . In the illustrated embodiment, the connector 345 forms an envelope around the wire of the coil 312. The wire of the connecting member 345 spirally wound around the coil 312 forms an envelope to be fixed to the coil 312. In the illustrated embodiment, the spirally wound strips 3451 are flush, non-overlapping, and free of gaps, thereby ensuring that the formed envelope is smooth and free of protrusions. Thus, the connector 345 can be bonded to the first diaphragm 341 and the second diaphragm 343 by heat fusion, and the connector 345 is thermally fused to form a coating covering the coil 312. It should be noted that the number of the connecting members 345 is not limited, and the envelope 345 may be wound by one connecting member 345 to form a coating film, or the plurality of connecting members 345 may be wound around the wave ring 312 to form a coating film. It will be appreciated that in other embodiments, the wire may be inserted into the expanded polytetrafluoroethylene hose to re-wrap the coil.

The thickness of the envelope formed by the connecting member 345 wound with the wave ring 312 affects the bonding strength between the bracket body 310 and the first diaphragm 341 and the second diaphragm 343. The larger the coating thickness, the larger the envelope and the first diaphragm 341 and the The bonding strength of the two sheets 343 is better. Preferably, the ratio of the sum of the thicknesses of the first diaphragm 341 and the second diaphragm 343 to the thickness of the envelope is 4:1 to 20:1.

It should be particularly noted that a thicker envelope will affect the compressive strength of the stent body 310. Therefore, it is preferable that the thickness of the envelope on the surface of the peak 3121 and the trough 3123 is smaller than the thickness of the envelope on the surface of the side bar 3125, thereby ensuring the bonding strength of the envelope to the first diaphragm 341 and the second diaphragm 343 while reducing The effect of the envelope on the compressive strength of the stent body 310. The ratio of the sum of the thicknesses of the first diaphragm 341 and the second diaphragm 343 to the thickness of the envelope of the peaks 3121 and the valleys 3123 is greater than 8:1, and the sum of the thicknesses of the first diaphragm 341 and the second diaphragm 343 is the sidebar The thickness ratio of the envelope of the 3125 surface is 2:1 to 6:1. In one of the embodiments, the ratio of the thickness of the envelope at the crests and troughs to the thickness of the envelope at the side bars is 1:1.5 to 1:3. It can be understood that, in an embodiment, the envelope may be provided only at the side bars of the coil, and there is no envelope at the crests and troughs of the coils. It will also be appreciated that envelopes of different thicknesses may be disposed in the axial direction of the surface of the wire of the coil 312, depending on the particular requirements for the performance of the stent graft 300. It will also be appreciated that different envelope thicknesses may also be provided in the circumferential direction of the wire of the coil 312. For example, the thickness of the envelope at both sides of the wire of the coil 312 is greater than the thickness at the first surface and the second surface. It should be noted that the two sides refer to a surface perpendicular to the first surface and the second surface. Preferably, the ratio of the thickness of the envelope at the two sides of the wire of the coil 312 to the distance between the first surface and the second surface of the wire is from 2:1 to 4:1 to further increase the wire. The strength of the connection to the film.

Referring to FIG. 10 and FIG. 11 simultaneously, in the illustrated embodiment, the connecting member 345 is spirally wound around the wire of the wave ring 312 to form a coating, and a gap formed by the spiral winding is formed with a gap, and the connecting member 345 wraps the wave ring. The formed envelope covers the surface of the coil portion. Of course, when the gap is small, the envelope formed by the fusion of the connecting member 345 can completely cover the surface of the coil 312. Of course, the gap can also be large under certain conditions, and the connecting member 345 can also form a discontinuous envelope on the surface of the wire.

Referring to FIG. 12, after the first diaphragm 341, the second diaphragm 343 and the connecting member 345 are thermally fusion-bonded by the laminating process, the connecting member 345 is hot-melted and coated on the surface of the bracket body 310 to form a coating. 345 fills the gap between the first diaphragm 341 and the second diaphragm 343, so that the bracket body 310 is fully fixed in the coating 340, and the connection strength between the bracket body 310 and the coating 340 is greatly improved, and the stent graft 300 is ensured. Stability and safety.

The stent body 300 is bonded and fixed to the first diaphragm 341 and the second diaphragm 343 by the connecting member 345 under the action of an external force, so that the first diaphragm 341 and the second diaphragm 343 are not easily adhered. Loosening occurs between them, reducing the risk of failure of the stent graft 300 due to displacement of the stent body 310 when the stent graft 300 is stressed or deformed.

Referring to FIG. 13 and FIG. 14 , the structure of the stent graft 400 of another embodiment is substantially the same as that of the stent graft 300 . The difference is that the stent body 410 of the stent graft 400 is a cut metal stent, and the connecting member 445 is An envelope formed by a coating applied to the surface of the stent body 410.

In the illustrated embodiment, the stent graft 400 is a stainless steel ball expanded membrane stent, and the coil 412 of the stent body 410 is a cut metal coil prepared by metal laser engraving. The cross section of the wave ring 412 is rectangular. Preferably, the four corners of the rectangle are rounded.

In one of the embodiments, the connector 445 is a coating formed by spraying, and the coating adheres to the surface of the coil 412 to form a coating. The material of the connecting member 445 is preferably expanded polytetrafluoroethylene.

In one embodiment, the thickness of the first film 441 and the second film 445 is 4:1 to 20:1.

In one of the embodiments, the thickness of the envelope of the surface of the peak 4121 and the valley 4123 is less than the thickness of the envelope of the surface of the sidebar 3125. Preferably, the ratio of the sum of the thicknesses of the first diaphragm 341 and the second diaphragm 443 to the thickness of the envelope of the peaks 4121 and the valleys 4123 is greater than 8:1, and the thicknesses of the first diaphragm 441 and the second diaphragm 443 are The thickness ratio of the envelope on the surface of the side bar 4125 is 2:1 to 6:1.

In the above-mentioned stent graft 400, a coating is prepared on the surface of the stent body 410 to obtain a connecting member 445, and the first diaphragm 441, the second diaphragm 443 and the connecting member 445 are thermally fusion-bonded by a laminating process, and the connecting member is connected. The 445 hot-melt coating forms a coating on the surface of the bracket body 410, and the connecting member 445 fills the gap between the first diaphragm 441 and the second diaphragm 443, so that the bracket body 410 is sufficiently fixed in the coating 440. The bracket body 410 The connection strength with the film 440 is greatly improved, and the stability and safety of the film stent 400 are ensured.

The stent graft 400 is bonded and fixed to the first diaphragm 441 and the second diaphragm 443 by the connecting member 445 under the action of an external force, so that the first diaphragm 441 and the second diaphragm 443 are not easily attached. Loosening occurs between them, reducing the risk of failure of the stent graft 400 due to displacement of the stent body 410 when the stent graft 400 is stressed or deformed.

Referring to FIGS. 15 and 16 , the structure of the stent graft 500 of another embodiment is substantially the same as that of the stent graft 400 , except that the surface of the coil 512 of the stent graft 500 is formed with a groove 521.

In the illustrated embodiment, the recess 5121 is recessed inwardly from the first surface of the coil 512. Of course, in other embodiments, the recess 5121 may also be recessed inward from the second surface of the coil 512, or The first surface and the second surface of the wave ring 512 are each formed with a groove.

In the illustrated embodiment, the recess 5121 is a blind slot. Of course, in other embodiments, the recess 5121 can also be a through slot, and the recess 5121 extends through the first surface and the second surface.

Referring to FIG. 15 , FIG. 17 and FIG. 18 , when the surface of the wave ring 512 is sprayed to form the envelope enclosing the wave ring 512 as the connecting member 545 , the material of the coating fills the groove 5121 , so that the connecting member 545 can be added. The adhesive force between the wave ring 512, the portion received in the groove 5121 becomes an anchor point connecting the connecting member 545 and the wave ring 512, and the connecting member 545 and the first diaphragm 541 and the second diaphragm 543 are thermally melt-bonded. In time, the connection between the bracket body and the first diaphragm 541 and the second diaphragm 543 is more stable.

It can be understood that the connecting member 545 is not limited to the envelope of the coated wave ring 512 formed by spraying. In other embodiments, the connecting member 545 may also be spirally wound around the envelope of the wave ring 512. After the hot pressing process, the connecting member 545, the first diaphragm 541 and the second diaphragm 543 are hot-melted to fill the recess 5121. Of course, it can be understood that the coating applied to the wave ring 512 can also be omitted. After the hot pressing treatment of the coating film, the first film piece 541 and the second film piece 543 are melted and filled into the groove 5121 to be received in the concave shape. The protrusion of the groove serves as a connecting member, and the connecting member is received and fixed to the groove at this time, and becomes an anchor point connecting the film and the coil 512. When the external force is applied, the bracket body 510 is adhered and fixed to the first diaphragm 541 and the second diaphragm 543 through the connecting member 545, so that loosening between the first diaphragm 541 and the second diaphragm 543 is not easy, and the reduction is reduced. The displacement of the stent body 510 when the stent graft 500 is stressed or deformed poses a risk of failure of the stent graft 500.

The method for preparing the above-mentioned stent graft comprises the following steps:

Step S710, providing a stent body.

The bracket body has a first surface and a second surface opposite the first surface. The bracket body includes a wave ring.

In one of the embodiments, at least one of the first surface and the second surface of the stent body is recessed inwardly to form a groove.

Step S720, forming a connector for wrapping the bracket body on the bracket body.

In one of the embodiments, the connector is wrapped around the stent body to form a wrap that surrounds the stent body. Preferably, the connector is spirally wound around the coil. Further preferably, the strips formed by the connectors wound by the coils are flush, non-overlapping, and free of gaps to ensure smooth formation of the envelope without protrusions. Of course, in other embodiments, a gap is formed between the stripes formed by the connectors spirally wound around the coil.

Further, the thickness of the connector of the peak and trough surface is less than the thickness of the connector of the side bar surface. It will be appreciated that in one embodiment it is also possible to wrap the connector only at the side bars of the coil, not at the crests and troughs of the wave ring.

In one of the embodiments, a coating is formed on the surface of the stent body to obtain a connector. Preferably, the coating is obtained by spraying, spin coating or knife coating to form a coating. In one of the embodiments, the thickness of the coating of the crest and trough surface is less than the thickness of the coating of the side bar surface. It will be appreciated that in one embodiment, it is also possible to apply the coating only at the side bars of the coils, without coating at the crests and troughs of the coils. It will also be appreciated that different coating thicknesses may also be provided in the circumferential direction of the coil. For example, the thickness at both sides of the wire of the coil is greater than the thickness of the coating at the first and second surfaces. Preferably, the thickness of the coating at both sides of the coiled wire is a ratio of the distance between the first surface of the wire and the second surface of from 2:1 to 4:1.

In one of the embodiments, the connector is a hose that is sleeved over the coil of the stent.

In one of the embodiments, the material of the connector is expanded polytetrafluoroethylene. In other embodiments, the material of the connector may also be an adhesive such as polyperfluoroethylene propylene (FEP).

Step S730, the first diaphragm is disposed on the first surface of the bracket body, the second diaphragm is disposed on the second surface of the bracket body, and the first diaphragm and the second diaphragm are heat treated to make the first diaphragm and the first diaphragm The two membranes are adhesively fixed.

The material of the first diaphragm and the second diaphragm is expanded polytetrafluoroethylene, and the materials of the first diaphragm, the second diaphragm and the connecting member are the same. Of course, in other embodiments, at least one of the first diaphragm and the second diaphragm may be the same material as the connector. It can be understood that when the material of the connecting member is an adhesive, the material of the connecting member may be different from the materials of the first diaphragm and the second diaphragm.

In this step, the first film and the second film are heat-treated to thermally bond the first film and the second film, and the first film and the second film are thermally bonded to the connecting member. In the case where a groove is formed on the surface of the stent body, the connector wound around the stent body is thermally melted to fill the groove.

The preparation method of the above-mentioned stent graft is simple in operation, and the prepared stent graft can improve the joint strength between the membrane and the stent.

It can be understood that the groove of the surface of the bracket body can be omitted, and forming the envelope directly on the body of the bracket can also improve the connection strength between the film and the bracket. Step S720 can be omitted. The first diaphragm is directly disposed on the first surface of the bracket body having the groove on the surface, and the second diaphragm is disposed on the second surface of the bracket body to heat treat the first diaphragm and the second diaphragm. The first film and the second film are bonded and fixed, and at least one of the first film and the second film covering the surface of the groove is filled and fixed in the groove. Connector. Of course, in order to better fill the groove, the surface of at least one of the first diaphragm and the second diaphragm may be disposed on the corresponding protrusion of the groove. After the heat fusion, the protrusion is received and fixed to the groove to form a connection. Pieces. It should be noted that the groove may be a through groove, penetrate the first surface and the second surface of the wave ring, and the first film and the second film are hot-melted and filled into the groove to obtain the first film and the second film simultaneously Membrane-attached connector.

The technical features of the above-described embodiments may be arbitrarily combined. For the sake of brevity of description, all possible combinations of the technical features in the above embodiments are not described. However, as long as there is no contradiction between the combinations of these technical features, All should be considered as the scope of this manual.

The above-described embodiments are merely illustrative of several embodiments of the present invention, and the description thereof is more specific and detailed, but is not to be construed as limiting the scope of the invention. It should be noted that a number of variations and modifications may be made by those skilled in the art without departing from the spirit and scope of the invention. Therefore, the scope of the invention should be determined by the appended claims.

Claims

A stent graft comprising a stent body and a coating, the stent body having a first surface and a second surface opposite to the first surface, the coating comprising a first membrane and a second membrane The first film is disposed on the first surface, and the second film is disposed on the second surface and bonded to the first film, wherein the film further comprises a connector body fixed to the bracket body, the connecting member is located between the first diaphragm and the second diaphragm, and the connecting member is at least at least one of the first diaphragm and the second diaphragm One bond.
The stent graft of claim 1 wherein said connector is an envelope encasing said stent body.
The stent graft according to claim 2, wherein a ratio of a thickness of the first membrane and the second membrane to a thickness of the envelope is 4:1 to 20:1.
The stent graft according to claim 2, wherein the stent body comprises a wave ring, the wave circle comprises a wave crest, a trough and a side bar, the side bar connecting the crest and the trough, the crest and The thickness of the envelope of the trough surface is less than the thickness of the envelope of the side rod surface.
The stent graft according to claim 1, wherein at least one of the first surface and the second surface is recessed inwardly to form a groove, and the connecting member is received in and fixed to the groove. .
The stent graft of claim 1 wherein the material of the connector is the same as the material of the first membrane and/or the second membrane.
The method for preparing a stent graft according to claim 1, comprising the steps of:

Forming a connector covering the bracket body on the bracket body; and

The first diaphragm is disposed on the first surface of the bracket body, and the second diaphragm is disposed on the second surface of the bracket body, the first diaphragm and the second diaphragm The first film, the second film, and the connecting member are bonded and fixed by heat treatment.
The method for manufacturing a stent graft according to claim 8, wherein the step of forming a connector covering the stent body on the stent body is specifically: winding the connector around the stent The body forms an envelope encasing the stent body.
The method for preparing a stent graft according to claim 8, wherein the step of forming a connector covering the stent body on the stent body is specifically: forming a coating on the surface of the stent body The connector.
The method for preparing a stent graft according to claim 1, comprising the steps of:

Providing the bracket body, at least one of the first surface and the second surface of the bracket body is recessed inward to form a groove;

The first diaphragm is disposed on the first surface of the bracket body, and the second diaphragm is disposed on the second surface of the bracket body, the first diaphragm and the second diaphragm Performing a heat treatment to bond the first film to the second film, and at least one of the first film and the second film is filled with the groove after heat treatment to be received and fixed to the concave The connector of the slot.