WO2019016410A8 - Nebulizer - Google Patents

Nebulizer Download PDF

Info

Publication number
WO2019016410A8
WO2019016410A8 PCT/EP2018/069947 EP2018069947W WO2019016410A8 WO 2019016410 A8 WO2019016410 A8 WO 2019016410A8 EP 2018069947 W EP2018069947 W EP 2018069947W WO 2019016410 A8 WO2019016410 A8 WO 2019016410A8
Authority
WO
WIPO (PCT)
Prior art keywords
container
liquid
nebulizer
withdrawing
doses
Prior art date
Application number
PCT/EP2018/069947
Other languages
French (fr)
Other versions
WO2019016410A1 (en
Inventor
Heinrich Kladders
Thomas Wabnitz
Herbert Graessl
Andree Jung
Gilbert Wuttke
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to KR1020207005014A priority Critical patent/KR20200032723A/en
Priority to IL271867A priority patent/IL271867B2/en
Priority to EP21169710.7A priority patent/EP3884976A1/en
Priority to JP2020502484A priority patent/JP7155234B2/en
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Priority to EP18749744.1A priority patent/EP3655078B1/en
Priority to AU2018303702A priority patent/AU2018303702B2/en
Priority to CN201880048117.3A priority patent/CN111032133B/en
Priority to CA3070097A priority patent/CA3070097A1/en
Priority to US16/631,274 priority patent/US20200215275A1/en
Priority to CN202211184103.9A priority patent/CN115700123A/en
Publication of WO2019016410A1 publication Critical patent/WO2019016410A1/en
Publication of WO2019016410A8 publication Critical patent/WO2019016410A8/en
Priority to PH12020500151A priority patent/PH12020500151A1/en
Priority to JP2022160889A priority patent/JP7402291B2/en
Priority to US18/539,675 priority patent/US20240108822A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0073—Mechanical counters having a display or indicator on a ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081—Locking means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • B05B11/026—Membranes separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/108—Means for counting the number of dispensing strokes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
    • B05B11/1091—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring being first hold in a loaded state by locking means or the like, then released
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/16—Closures not otherwise provided for with means for venting air or gas
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06M—COUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
    • G06M1/00—Design features of general application
    • G06M1/04—Design features of general application for driving the stage of lowest order
    • G06M1/041—Design features of general application for driving the stage of lowest order for drum-type indicating means
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06M—COUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
    • G06M1/00—Design features of general application
    • G06M1/22—Design features of general application for visual indication of the result of count on counting mechanisms, e.g. by window with magnifying lens
    • G06M1/24—Drums; Dials; Pointers
    • G06M1/241—Drums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/27—General characteristics of the apparatus preventing use
    • A61M2205/273—General characteristics of the apparatus preventing use preventing reuse, e.g. of disposables

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nozzles (AREA)

Abstract

A nebulizer (1) for nebulizing a liquid (2) from a container (3) is proposed. The nebulizer comprises a fluid pump (5) for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The nebulizer comprises in addition an air pump (30) with a piston / cylinder arrangement (31, 32) for pumping air into the container to pressurize the liquid in the container to help withdrawing the liquid from the container.
PCT/EP2018/069947 2017-07-21 2018-07-23 The present invention relates to a nebulizer according to the preamble of claim 1 WO2019016410A1 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
AU2018303702A AU2018303702B2 (en) 2017-07-21 2018-07-23 Nebulizer
EP21169710.7A EP3884976A1 (en) 2017-07-21 2018-07-23 Nebulizer
JP2020502484A JP7155234B2 (en) 2017-07-21 2018-07-23 nebulizer
CA3070097A CA3070097A1 (en) 2017-07-21 2018-07-23 Nebulizer
EP18749744.1A EP3655078B1 (en) 2017-07-21 2018-07-23 Nebulizer
IL271867A IL271867B2 (en) 2017-07-21 2018-07-23 Nebulizer
CN201880048117.3A CN111032133B (en) 2017-07-21 2018-07-23 Sprayer with a spray tube
KR1020207005014A KR20200032723A (en) 2017-07-21 2018-07-23 sprayer
US16/631,274 US20200215275A1 (en) 2017-07-21 2018-07-23 Nebulizer
CN202211184103.9A CN115700123A (en) 2017-07-21 2018-07-23 Sprayer unit
PH12020500151A PH12020500151A1 (en) 2017-07-21 2020-01-21 Nebulizer
JP2022160889A JP7402291B2 (en) 2017-07-21 2022-10-05 nebulizer
US18/539,675 US20240108822A1 (en) 2017-07-21 2023-12-14 Nebulizer

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP17020317.8 2017-07-21
EP17020316.0 2017-07-21
EP17020317 2017-07-21
EP17020316 2017-07-21
EP2018069834 2018-07-20
EPPCT/EP2018/069834 2018-07-20

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US16/631,274 A-371-Of-International US20200215275A1 (en) 2017-07-21 2018-07-23 Nebulizer
US18/539,675 Continuation US20240108822A1 (en) 2017-07-21 2023-12-14 Nebulizer

Publications (2)

Publication Number Publication Date
WO2019016410A1 WO2019016410A1 (en) 2019-01-24
WO2019016410A8 true WO2019016410A8 (en) 2019-05-16

Family

ID=63103912

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2018/069947 WO2019016410A1 (en) 2017-07-21 2018-07-23 The present invention relates to a nebulizer according to the preamble of claim 1

Country Status (11)

Country Link
US (2) US20200215275A1 (en)
EP (2) EP3655078B1 (en)
JP (2) JP7155234B2 (en)
KR (1) KR20200032723A (en)
CN (2) CN111032133B (en)
AU (1) AU2018303702B2 (en)
CA (1) CA3070097A1 (en)
CL (1) CL2020000149A1 (en)
IL (1) IL271867B2 (en)
PH (1) PH12020500151A1 (en)
WO (1) WO2019016410A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL271867B2 (en) * 2017-07-21 2023-10-01 Boehringer Ingelheim Int Nebulizer
CN109907968B (en) * 2019-04-19 2021-06-04 常州市第一人民医院 Eye fumigation nursing device based on new material is made
EP3935972B1 (en) * 2020-07-07 2023-09-06 Aptar Radolfzell GmbH Oral dispenser for liquids, especially for liquids containing nicotine or cannabis
CN113967299A (en) * 2020-07-22 2022-01-25 苏州天健云康信息科技有限公司 Atomization device and counting module for atomization device
CN112156286B (en) * 2020-10-10 2022-06-28 南阳市中心医院 Otology patient medicine delivery device for medical treatment
KR102630826B1 (en) * 2021-10-18 2024-01-29 주식회사 파인메딕스 Hemostatic spray

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3940030A (en) * 1974-08-16 1976-02-24 Hirosi Kondo Dispenser device for taking out contents
DE3302160A1 (en) * 1983-01-22 1984-07-26 Ing. Erich Pfeiffer GmbH & Co KG, 7760 Radolfzell OPERATING DOSING DEVICE
FR2650763A1 (en) * 1989-08-10 1991-02-15 Bedou Patrick Rechargeable portable spray (atomiser) for liquids
US5267674A (en) * 1991-06-26 1993-12-07 Robert Finke Gmbh & Co. Kg Container for the spray-dispensing of liquid
DE4428434A1 (en) 1994-08-11 1996-02-15 Boehringer Ingelheim Kg Sealing cap and method for filling gas-free containers
DE19940713A1 (en) 1999-02-23 2001-03-01 Boehringer Ingelheim Int Diffusion resistant cartridge for storing and dosing liquids, especially for producing drug-containing inhalable aerosols, has three-shell structure with collapsible bag, container and rigid housing
DE10154237A1 (en) * 2001-11-07 2003-05-15 Steag Microparts Gmbh Manual sputterer, to spray liquid droplets on to a surface, has a spring acting on a piston with a manual release, to spray a portion of the stored liquid with a controlled droplet size
DE10239443A1 (en) 2002-08-28 2004-03-11 Boehringer Ingelheim International Gmbh Mechanism comprising a bent leaf spring, is useful for blocking further operation of a device after a specified number of relative rotations of parts of this device
FR2854878B1 (en) * 2003-05-15 2006-03-31 Valois Sas FLUID PRODUCT DISPENSER.
US7703454B2 (en) * 2003-07-14 2010-04-27 Vortran Medical Technology Inhaler with breath actuated dose counter
WO2006016726A1 (en) * 2004-08-12 2006-02-16 Idec Corporation Counter mechanism of feeder and feeder having counter mechanism
EP2044967A1 (en) 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Atomiser
UA101364C2 (en) 2008-03-17 2013-03-25 Берингер Ингельхайм Интернациональ Гмбх Reservoir for nebulizer
WO2010094305A1 (en) 2009-02-18 2010-08-26 Boehringer Ingelheim International Gmbh Device, cartridge and method for dispensing a liquid
US10080853B2 (en) * 2011-05-23 2018-09-25 Boehringer Ingelheim International Gmbh Nebulizer
WO2012161685A1 (en) 2011-05-23 2012-11-29 Boehringer Ingelheim International Gmbh Nebulizer
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US10973997B2 (en) * 2016-01-25 2021-04-13 Boehringer Ingelheim International Gmbh Nebulizer
IL271867B2 (en) * 2017-07-21 2023-10-01 Boehringer Ingelheim Int Nebulizer

Also Published As

Publication number Publication date
JP7402291B2 (en) 2023-12-20
US20240108822A1 (en) 2024-04-04
CL2020000149A1 (en) 2020-06-12
AU2018303702A1 (en) 2020-01-16
IL271867B2 (en) 2023-10-01
WO2019016410A1 (en) 2019-01-24
JP7155234B2 (en) 2022-10-18
JP2023011582A (en) 2023-01-24
EP3884976A1 (en) 2021-09-29
CN115700123A (en) 2023-02-07
KR20200032723A (en) 2020-03-26
IL271867A (en) 2020-02-27
IL271867B1 (en) 2023-06-01
US20200215275A1 (en) 2020-07-09
CN111032133B (en) 2022-10-21
EP3655078B1 (en) 2021-06-02
CN111032133A (en) 2020-04-17
CA3070097A1 (en) 2019-01-24
PH12020500151A1 (en) 2020-09-14
AU2018303702B2 (en) 2023-09-21
EP3655078A1 (en) 2020-05-27
JP2020527081A (en) 2020-09-03

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