WO2018191902A1 - Dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et de traitement et son procédé de fonctionnement - Google Patents

Dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et de traitement et son procédé de fonctionnement Download PDF

Info

Publication number
WO2018191902A1
WO2018191902A1 PCT/CN2017/081199 CN2017081199W WO2018191902A1 WO 2018191902 A1 WO2018191902 A1 WO 2018191902A1 CN 2017081199 W CN2017081199 W CN 2017081199W WO 2018191902 A1 WO2018191902 A1 WO 2018191902A1
Authority
WO
WIPO (PCT)
Prior art keywords
patient
anesthesia
treatment
virtual reality
anesthetic
Prior art date
Application number
PCT/CN2017/081199
Other languages
English (en)
Chinese (zh)
Inventor
陈昳丽
李新宇
付楠
余绍德
朱艳春
赵屾
谢耀钦
Original Assignee
中国科学院深圳先进技术研究院
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 中国科学院深圳先进技术研究院 filed Critical 中国科学院深圳先进技术研究院
Priority to PCT/CN2017/081199 priority Critical patent/WO2018191902A1/fr
Publication of WO2018191902A1 publication Critical patent/WO2018191902A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks

Definitions

  • the invention relates to an auxiliary diagnosis and treatment device for local anesthesia treatment and an operation method thereof
  • the present invention belongs to the technical field of medicine, and in particular, to an auxiliary medical treatment apparatus for local anesthesia treatment and an operation method thereof.
  • the anesthetic effect of anesthetic is not absolutely ideal, and still has a certain pain.
  • the main analgesia is mainly oral local anesthesia, using a syringe to puncture the oral mucosa to push the anesthetic, although the anesthetic effect depends on the medical treatment of the therapist Level, but also limited by the day. Therefore, the fear of patients undergoing pain during treatment is a core issue in comfort diagnosis and treatment. In general, pain is often accompanied by strong emotional reactions such as panic and nervousness. Psychic pleasure and fearlessness, painlessness stem from the attitude and environment of the medical staff and their psychological qualities, if the patient develops anxiety and fear during the treatment.
  • the object of the present invention is to overcome the above deficiencies of the prior art, and to provide an auxiliary medical treatment device for local anesthesia treatment and an operation method thereof, which can reduce the pain of the patient's diagnosis and treatment, and has good treatment comfort and reliability. High sexuality reduces the psychological burden of the patient and ensures the smooth progress of the treatment process.
  • the present invention is achieved by: an auxiliary medical treatment apparatus for local anesthesia treatment, including a medical treatment apparatus, and an anesthesia stabilization system for local anesthesia of a surgical site of a patient and for providing video content to enable A virtual reality device that distracts a patient's pain or/and fear, the virtual reality device being fixedly attached to the patient's head by wearing a structure.
  • the wearing structure includes a fixing belt and is disposed on the fixing belt for adjusting the wearing tightness
  • the adjusting buckle is disposed on the fixing strap.
  • the anesthesia stabilization system includes a conveyor for anesthetizing an anesthetic to anesthetize the patient, and an operator for anesthesia for connection with the patient, the conveyor and the operator Connected by a duct.
  • the anesthetic is an anesthetic gas
  • the operator is a nasal mask for wearing on the nose of the patient.
  • the present invention also provides an operation method of the auxiliary medical treatment apparatus, which adopts the above-mentioned auxiliary medical treatment apparatus, and the operation method includes the following steps:
  • a pre-operative preparation step including preparation of the anesthesia stabilization system and the virtual reality device;
  • connection wearing step including connecting the anesthesia stabilization system to a patient and wearing the virtual reality device on the patient's head;
  • an operation control step comprising: controlling the output of the anesthetic by the anesthesia stabilization system and selecting a content to be played by the virtual reality device according to a condition or/and a patient demand;
  • postoperative recovery steps including control of postoperative oxygen concentration and oxygen supply;
  • Cleaning step including closing and cleaning the auxiliary medical device.
  • the commissioning of the anesthesia stabilization system includes an inspection of the reliability of the connection with the patient.
  • the debugging preparation of the virtual reality device includes adjusting the wearing tension of the device according to the condition of the patient.
  • the anesthetic is an anesthetic gas
  • the specific operation for controlling the output of the anesthetic is: first, the patient is inhaled with pure oxygen for 1 min, and then the inhalation concentration is 30 by the anesthesia stabilization system.
  • the anesthetic agent of % is for 1 min, and then the concentration of the anesthetic content is increased by a range of 5 ⁇ 3 ⁇ 4 to 10 ⁇ 3 ⁇ 4 every interval of 1 min, and the inhalation value of the inhalation is determined according to the sedation state of the patient.
  • the specific operation of the post-operative recovery step is: closing the anesthesia stabilization system, and determining the concentration of the post-operative oxygen supply and the oxygen supply according to the usage amount of the anesthetic.
  • the specific operation of the cleaning step is: closing, collecting, and performing a disinfection cleaning process, and recording the vital sign data of the patient.
  • the present invention provides an auxiliary diagnosis and treatment device for local anesthesia treatment and an operation method thereof.
  • the anesthesia is used to perform anesthesia of the surgical site, and the virtual reality device is used to make the patient Emotionally relax, so that a more comfortable diagnosis and treatment process can be achieved during surgery.
  • the operation steps of the auxiliary medical treatment device are simple and convenient for the operation of the doctor.
  • the invention has the beneficial effects that the comfort treatment is achieved by combining the anesthetic with the virtual reality, the comfort of the treatment process and the safety of the patient are greatly improved, the psychological and physiological negative effects of the patient are alleviated, and the treatment process is ensured. Stable.
  • FIG. 1 is a schematic flow chart of a diagnosis and treatment method according to an embodiment of the present invention.
  • An auxiliary medical treatment apparatus for local anesthesia treatment provided in an embodiment of the present invention includes a medical treatment apparatus, which is a device that must be used to satisfy the corresponding treatment.
  • the auxiliary medical treatment device is described by taking the treatment of the tooth as an example, but it is not used as a basis for limiting the auxiliary medical treatment device only for dental treatment.
  • the medical equipment can also be used in other treatments that require local anesthesia, such as childbirth surgery, wound suture surgery or appendectomy.
  • the medical instrument may be an oral X-ray machine, an intraoral device, an extraoral device, an orthodontic device, a prosthetic device, or the like.
  • the patient sits on the treatment chair or lies on the treatment table, and then uses the corresponding surgical instrument to perform surgical treatment on the surgical site of the patient according to the actual treatment process.
  • the auxiliary medical treatment apparatus for local anesthesia treatment provided in the embodiment of the present invention further comprises local anesthesia for the surgical site of the patient.
  • the anesthesia stabilization system and the virtual reality device for providing video content to disperse the patient's pain and the virtual reality device is fixedly attached to the patient's head by wearing the structure, is convenient to wear, has good stability, and satisfies the use requirement.
  • the anesthetic is provided by the anesthesia stabilization system to anesthetize the patient, and the virtual reality device is equipped with an emotional game and video for relieving emotions, and the patient uses the virtual reality device to distract the patient from the pain. , thereby reducing the perception of pain.
  • the patient achieves physical and psychological comfort, can reduce more pain during the diagnosis and treatment process, thereby reducing the patient's discomfort It is conducive to the smooth progress of the operation.
  • the awake analgesia technique relies on a drunkenness system to use a certain concentration of anesthetic to perform local anesthesia on the patient, such as inhalation of anesthetic gas or oral anesthetic or injection of anesthetic for anesthesia. Therefore, the anesthesia type of the anesthesia stabilization system can be selected according to the needs of the actual operation.
  • the virtual reality device integrates the latest developments of computer graphics (CG) technology, computer simulation technology, artificial intelligence, sensing technology, display technology, network parallel processing, and the like. It is a high-tech simulation system generated by computer technology.
  • CG computer graphics
  • Using computer simulation to create a three-dimensional virtual world providing users with simulations of visual, auditory, tactile and other senses, allowing users to observe things in the three-dimensional space as if they were immersive and unrestricted.
  • virtual reality technology Compared with traditional static, textual, and two-dimensional image information presentation, virtual reality technology exhibits interactivity, experience, efficiency, and comprehensiveness.
  • the patient selects content that is of interest to him, such as a game or video, and can distract the harmful stimuli by watching the video in the device or the game in the play setting, reducing the transmission of pain signals and Perceive, increase attention to pleasure, and thus reduce interference with surgery.
  • the wearing structure includes a fixing strap and an adjusting buckle disposed on the fixing strap for adjusting the wearing tightness , the adjustment buckle is placed on the fixing strap.
  • the adjustment buckle can be used to adjust the tightness of the wearing of the virtual reality device according to the difference of the patient, so as to meet the use requirements in different situations.
  • the anesthesia stabilization system includes a gas conveyor for outputting an anesthetic gas and a nasal mask for the patient to wear a connection, and the gas conveyor and the nasal mask are connected through a gas pipe.
  • the anesthetic gas is selected to anesthetize the patient, and the anesthetic gas is Nitrosium Oxide, also known as laughing gas, which is a paralytic drug used for treating teeth, and can suppress central nervous system excitability. It inhibits the release of neurotransmitters and the transmission of nerve impulses. It has no irritation to the respiratory tract and has no damage to important organs such as heart, lung, liver and kidney.
  • the gas delivery device is used to deliver the anesthetic gas that needs to be used during the treatment to the patient, and the nasal mask is worn on the patient's nose, thereby facilitating the patient to absorb the delivered anesthetic gas.
  • an operation method of the auxiliary medical treatment device is further provided, and the auxiliary medical treatment device described above may be used. As shown in FIG. 1 , the operation method includes the following steps:
  • Pre-operative preparation step S1 including preparation preparation S11 of the anesthesia stabilization system and preparation preparation S12 of the virtual reality device, ensuring that the anesthesia stabilization system can be normally used, and the virtual reality device can normally play the video content, ensuring the course of the operation.
  • Peer-to-peer also needs to introduce the patient's steps and the functional function of the related equipment, so that the patient can have a corresponding understanding of the whole operation, avoiding panic and affecting the operation.
  • the connection wearing step S2 includes connecting the anesthesia stabilization system to the patient S21 and wearing the virtual reality device on the patient's head S22. That is, according to the needs of surgical treatment, the anesthesia stabilization system is connected with the patient. For example, when the anesthesia stabilization system uses gas anesthesia, the nasal mask in the anesthesia stabilization system is worn on the patient's nose, so that the patient can smoothly take the surgical treatment. The gas that needs to be used in the process. At the same time, the virtual reality device is worn on the head of the human body, ensuring that the patient can watch the content being played to distract the attention of the surgery and reduce the emotion during the surgical treatment of the patient.
  • Operation control step S3 comprising controlling the anesthesia stabilization system to output an anesthetic S31 and selecting a virtual reality device to play content according to the condition or/and the patient's needs S32.
  • the anesthesia stabilization system is controlled to anesthetize the patient. That is, depending on the situation, the type of anesthetic and the dose of anesthesia are selected. For example, when anesthesia gas is selected for anesthesia, the amount of gas used for the anesthetic gas, the concentration of the anesthetic gas, and the time required for the patient to inhale, thereby ensuring reliable anesthetic effect, and facilitating The operation is carried out.
  • Postoperative recovery step S4 Including control of postoperative oxygen concentration and oxygen supply S41. Due to surgery
  • the patient when the patient achieves anesthesia by inhaling anesthetic gas, in order to prevent hypoxemia, after the operation is completed, the patient needs to inhale a certain amount of pure oxygen for recovery, and the specific oxygen supply needs to be based on the patient's own The specific situation is controlled to ensure that the patient can recover normally. If you choose to inject anesthetic or oral anesthetics, you need the patient to wait for the anesthesia to be completely eliminated and the body to return to normal.
  • Cleaning step S5 includes closing and cleaning the auxiliary medical device S51. In order to ensure the normal operation of the next operation.
  • the commissioning S11 of the anesthesia stabilization system includes an examination of its functional reliability. That is, the type of anesthesia stabilization system is selected according to the condition of the operation, and the reliability of the function is checked. For example, when anesthesia gas is used for anesthesia, after the nasal mask of the anesthesia stabilization system is worn on the patient's nose, the airtightness of the nasal mask and the patient's wearing connection and the sealing of the delivery tube are checked to ensure that no Leaking gas, peers also need to check whether there is sufficient anesthetic gas and oxygen reserve, and check whether there is gas leakage in the air bag and the conveying pipe to ensure the sufficiency of preparation of each surgical condition and the sealing of the connection of each conveying pipe is reliable. Sex. If the injection method is used, the reliability of the injection device needs to be checked.
  • the preparation step of the virtual reality device includes performing device wearing adjustment according to the head shape of the patient, and the adjustment of the tightness can be performed by moving the adjustment buckle on the fixing belt.
  • the position is achieved to ensure the comfort and stability of wearing.
  • the peer selects the type of video playback content or interactive game according to the patient's own preference, to ensure that the use of the virtual reality device can distract the patient from the painful stimulation during the surgery, reduce the perception of pain, and achieve comfort.
  • the purpose of treatment is performed.
  • the anesthetic is an anesthetic gas, so the output anesthetic is controlled.
  • the specific operation of S31 is as follows: First, the patient is inhaled with pure oxygen for 1 min, then the anesthesia gas is supplied to the anesthesia gas stabilization system, and the concentration of the anesthetic gas is controlled, and the patient is initially inhaled to a concentration of 30%. Anesthetic gas, inhaled for 1 min, then increase the concentration of anesthetic gas in increments of 5 ⁇ 3 ⁇ 4 ⁇ 10 ⁇ 3 ⁇ 4 every interval of lmin, and ask the patient about the current anesthesia, as for the specific concentration increase. The value is based on the actual situation of the patient.
  • the inhaled value of the inhalation is determined according to the patient's sedation state. Due to the different physical conditions of different patients, the length of the inhalation of anesthetic gas is also different. According to clinical experience, the ideal inhalation can reach the ideal sedation state within 3 to 5 minutes, so that the operation can be performed. Guide the patient to the appropriate fit during the procedure.
  • per minute ventilation tidal volume X breathing times; and tidal volume refers to the amount of air inhaled or exhaled by calm breathing, which is related to age, gender, volume surface, breathing habits, body metabolism.
  • tidal volume inhalation X supply air flow rate, the longer the inhalation interval, the greater the tidal volume.
  • the adult is 8 ⁇ 10ml/kg and the child is 6 ⁇ 10ml/kg.
  • the corresponding medical device is required to observe and record the patient's own physiological characteristic index. For example, heart rate, respiration, and blood pressure oxygen saturation are measured and recorded to grasp the patient's preoperative vital characteristics data, and provide a reference for the treatment.
  • the specific operation of the postoperative recovery step is: closing the anesthesia stabilization system, and determining the concentration of the postoperative oxygen supply and the oxygen supply according to the amount of the anesthetic.
  • the anesthetic gas is stopped, and then a volume fraction of 1 oxygen is given for at least 5 minutes to prevent hypoxemia.
  • the greater the amount of anesthetic gas the longer the recovery needs, and some patients need to inhale oxygen for 15 minutes or even longer to return to normal. Therefore, according to the specific state of the postoperative patient, the time required for recovery is determined to ensure the patient's recovery health.
  • the specific operation of the cleaning step is: closing, collecting, and performing disinfection and cleaning processing, and recording vital vital signs data of the patient. That is, after the patient's postoperative recovery is completed, the oxygen supply is stopped, the virtual reality device is turned off, the vital signs are recorded, the medical records are written, the anesthetic gas is applied, the patient's feelings are interrogated, and the patient's state is known. Patient safety.
  • the auxiliary medical treatment device for local anesthesia treatment and the operation method thereof provided in the embodiments of the present invention, before performing the surgical treatment, first perform anesthesia of the surgical site by using an anesthetic gas, and are dispersed by using virtual reality equipment.
  • the patient's attention to pain, thereby reducing the perception of pain, allows the patient to relax emotionally, thereby achieving a more comfortable diagnosis and treatment process during surgery.
  • the use of virtual reality technology combined with the use of anesthetic gas, enables patients to achieve a more comfortable diagnosis and treatment process during surgery, compared with the traditional single analgesic method, the combination of virtual reality equipment and anesthesia stabilization system
  • the purpose of comfort and integrated treatment is to greatly improve the comfort of the treatment process and the safety of the patient, reduce the negative psychological and physiological effects of the patient, and ensure the stable and smooth treatment process.

Abstract

La présente invention concerne un dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et le traitement et son procédé de fonctionnement, applicable au domaine technique de la médecine. Le dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et le traitement comprend un instrument de diagnostic et de traitement, et comprend en outre un système de tranquillisation d'anesthésie utilisé pour l'anesthésie locale d'un site chirurgical d'un patient et un dispositif de réalité virtuelle utilisé pour fournir un contenu vidéo afin d'être capable d'alléger la douleur ou/et la crainte du patient ; le dispositif de réalité virtuelle est relié à demeure à la tête du patient à l'aide d'une structure à porter. Le procédé de fonctionnement utilise le dispositif de diagnostic et de traitement auxiliaire, et comprend une étape de préparation préopératoire (S1), une étape de fixation et de port (S2), une étape de fonctionnement et de commande (S3), une étape de récupération postopératoire (S4), et une étape de nettoyage (S5). Le dispositif de diagnostic et de traitement auxiliaire pour anesthésie locale et traitement et son procédé de fonctionnement peuvent soulager la douleur du patient durant le diagnostic et le traitement, présentent un bon confort de traitement et une haute fiabilité, réduisent la charge psychologique sur le patient, et garantissent que le procédé de traitement est exécuté facilement.
PCT/CN2017/081199 2017-04-20 2017-04-20 Dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et de traitement et son procédé de fonctionnement WO2018191902A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/081199 WO2018191902A1 (fr) 2017-04-20 2017-04-20 Dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et de traitement et son procédé de fonctionnement

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/081199 WO2018191902A1 (fr) 2017-04-20 2017-04-20 Dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et de traitement et son procédé de fonctionnement

Publications (1)

Publication Number Publication Date
WO2018191902A1 true WO2018191902A1 (fr) 2018-10-25

Family

ID=63855513

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2017/081199 WO2018191902A1 (fr) 2017-04-20 2017-04-20 Dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et de traitement et son procédé de fonctionnement

Country Status (1)

Country Link
WO (1) WO2018191902A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1485105A (zh) * 2002-09-27 2004-03-31 深圳市金科威实业有限公司 智能镇痛机
US20050216243A1 (en) * 2004-03-02 2005-09-29 Simon Graham Computer-simulated virtual reality environments for evaluation of neurobehavioral performance
CN101309731A (zh) * 2005-10-17 2008-11-19 转换注意力治疗技术有限公司 转移注意力治疗的设备、方法及交互式装置
CN103079622A (zh) * 2011-05-31 2013-05-01 石北直之 麻醉药吸入辅助装置及其附属装置
CN106110459A (zh) * 2016-07-27 2016-11-16 田鸣 一种麻醉用鼻罩
CN205698207U (zh) * 2016-03-01 2016-11-23 天津医科大学总医院 眼科手术护罩

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1485105A (zh) * 2002-09-27 2004-03-31 深圳市金科威实业有限公司 智能镇痛机
US20050216243A1 (en) * 2004-03-02 2005-09-29 Simon Graham Computer-simulated virtual reality environments for evaluation of neurobehavioral performance
CN101309731A (zh) * 2005-10-17 2008-11-19 转换注意力治疗技术有限公司 转移注意力治疗的设备、方法及交互式装置
CN103079622A (zh) * 2011-05-31 2013-05-01 石北直之 麻醉药吸入辅助装置及其附属装置
CN205698207U (zh) * 2016-03-01 2016-11-23 天津医科大学总医院 眼科手术护罩
CN106110459A (zh) * 2016-07-27 2016-11-16 田鸣 一种麻醉用鼻罩

Similar Documents

Publication Publication Date Title
Muzi et al. Induction of anesthesia and tracheal intubation with sevoflurane in adults
Brill How to avoid interface problems in acute noninvasive ventilation
Papa et al. Recent advances in interfaces for non-invasive ventilation: from bench studies to practical issues.
JP5323124B2 (ja) 意識下鎮静のための薬物送達システム
US6637434B2 (en) Nasal gas delivery system and method for use thereof
Florella et al. AUDIOVISUAL IATROSEDATION WITH VIDEO EYEGLASSES DISTRACTION METHOD IN PEDIATRIC DENTISTRY: CASE HISTORY.
Leelataweewud et al. The physiological effects of supplemental oxygen versus nitrous oxide/oxygen during conscious sedation of pediatric dental patients
Zhang et al. Improved sedation for dental extraction by using video eyewear in conjunction with nitrous oxide: a randomized, controlled, cross-over clinical trial
Riquelme et al. Face protective patches do not reduce facial pressure ulcers in a simulated model of noninvasive ventilation
Rolfe et al. Oxygen therapy in adult patients. Part 2: promoting safe and effective practice in patients' care and management
WO2018191902A1 (fr) Dispositif de diagnostic et de traitement auxiliaire pour l'anesthésie locale et de traitement et son procédé de fonctionnement
Khinda et al. Nitrous Oxide Inhalation Sedation Rapid Analgesia in Dentistry: An Overview of Technique, Objectives, Indications, Advantages, Monitoring, and Safety Profile
CN108721753A (zh) 用于局部麻醉治疗的辅助诊疗设备及其操作方法
Sanuki et al. Nitrous oxide inhalation sedation through a nasal high-flow system: The possibility of a new technique in dental sedation
Jiang Anesthesia for Outpatient Oral and Maxillofacial Surgery
Hallén Isocapnic hyperventilation in anaesthesia practice. Clinical and experimental studies
Riquelme M et al. Uso de parches protectores faciales no reduce la presión facial en un modelo simulado de ventilación mecánica no invasiva
Pertab Principles of non-invasive ventilation: a critical review of practice issues
Caironi et al. Monitoring Patients During Noninvasive Ventilation: The Clinical Point of View
CN208927315U (zh) 麻醉房
Goel Evolution of Anaesthesia
Li Anesthesia for Pediatric Oral and Maxillofacial Surgery
Anand et al. Using inhalation sedation in practice
Vaithialingam et al. Sevoflurane Induction With Snorkel Technique in an Adult With Mask and Needle Phobia
Assessment AN UNDERSTANDING OF NITROUS OXIDE–OXYGEN INHALATIONAL SEDATION IN DENTAL PRACTICE

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17906652

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 17906652

Country of ref document: EP

Kind code of ref document: A1

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 1205A DATED 25/08/2020)

122 Ep: pct application non-entry in european phase

Ref document number: 17906652

Country of ref document: EP

Kind code of ref document: A1