WO2018170792A1 - Method and system for assessing effectiveness of tui na on lumbar disc herniation - Google Patents

Method and system for assessing effectiveness of tui na on lumbar disc herniation Download PDF

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WO2018170792A1
WO2018170792A1 PCT/CN2017/077701 CN2017077701W WO2018170792A1 WO 2018170792 A1 WO2018170792 A1 WO 2018170792A1 CN 2017077701 W CN2017077701 W CN 2017077701W WO 2018170792 A1 WO2018170792 A1 WO 2018170792A1
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disc herniation
lumbar disc
massage
patients
patient
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PCT/CN2017/077701
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French (fr)
Chinese (zh)
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孙像君
李慧慧
杜文静
陈文敏
周芳
王磊
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中国科学院深圳先进技术研究院
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Priority to PCT/CN2017/077701 priority Critical patent/WO2018170792A1/en
Publication of WO2018170792A1 publication Critical patent/WO2018170792A1/en

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  • the invention relates to a method and a system for evaluating the massage effect of a patient with lumbar disc herniation.
  • Lumbar disc herniation is a common and frequently-occurring disease in orthopedics. It is the most common cause of low back pain. It causes great pain to patients, such as work ability, learning ability, quality of life, and even disability. Clinically, there are a variety of conservative methods for non-surgical indications of LDH patients.
  • Traditional Chinese medicine has unique insights and methods, such as manual massage, oral Chinese medicine prescription, topical Chinese medicine ointment, acupuncture, etc., which have been accepted by doctors and patients. good idea.
  • the massage has the functions of warming meridians, relieving muscle spasm, relaxing pain, etc.
  • the manipulation can correct the anatomy of the soft tissue or the facet joint of the displacement. Position, make the abnormal line of force return to normal, adjust the internal and external balance, relieve the symptoms of clinical pain, numbness and other symptoms to improve blood circulation, enhance muscle strength, improve the elasticity of the ligament and eliminate inflammation.
  • Indirect inhalation of the spinal cord and other methods can affect the spinal cord and The nerve roots produce friction, and it is expected to improve the microcirculation, promote the function of edema washing and loosening the adhesion, and the nerves are repaired, and the dysfunction is alleviated and disappeared.
  • Imaging evaluation methods include X-ray, computed tomography (CT) and magnetic resonance imaging (MRI).
  • CT computed tomography
  • MRI magnetic resonance imaging
  • CT can obtain data on different supine positions in the waist, find anatomical changes, use data for 3D reconstruction and measurement;
  • MRI can obtain sagittal plane, Images of coronal, cross-sectional, and cross-sections in any direction, capable of Direct 3D reconstruction showed that the method used a supine vertebral body.
  • Patients with lumbar disc herniation are manifested in spinal injury and often show abnormalities in spinal motion.
  • the above imaging radiological examination methods may not be easy to show abnormalities.
  • the score assessment method includes the pain visual analog scale scale, the dysfunction index questionnaire, and the lumbar spine function score scale. Pain visual analogue scale scale, the method is more sensitive and comparable. The specific method is: draw a 10cm horizontal line on the paper, one end of the horizontal line is 0, indicating no pain, the other end is 10, indicating severe pain. The middle part indicates different degrees of pain, allowing the patient to draw a mark on the horizontal line according to the feeling of self, indicating the degree of pain.
  • the dysfunction index questionnaire consists of 10 questions, including the intensity of pain, self-care, walking, walking, sitting, standing, disturbing sleep, sex life, social life, tourism, etc., each question 6 Options, the highest score for each question is 5 points, the first option is 0 points, and the last option is 5 points. If there are 10 questions, the scoring method is: actual score / 50 (highest possible score) ⁇ 100%, if there is a question that is not answered, the scoring method is: actual score / 45 (highest possible score) ⁇ 100%, if the higher indicates that the dysfunction is more serious.
  • the characteristic values of the extracted lumbar disc herniation patients before and after massage were statistically analyzed, and the changes of EEG signals before and after massage were analyzed to find out the channels or rhythms with significant differences;
  • the instrument for collecting electroencephalogram data of the patient with lumbar disc herniation is an EMOTIV EPOC brain electricity collecting instrument.
  • the electrode placement of the EMOTIV EPOC EEG is performed using the international 10/20 system standard, the electrode simultaneously recording 14 conductive EEG data, and the 14 channels of the 14 conductive electrodes are respectively AF3. , F7, F3, FC5, T7, P7, O1, O2, P8, T8, FC6, F4, F8, AF4, the electrode is an Ag/AGCI electrode, and the EEG sampling frequency of the EMOTIV EPOC brain electricity collecting instrument is At 128 Hz, the band of the electroencephalogram data of the patient with lumbar disc herniation includes a ⁇ wave of 1 to 3 Hz, a ⁇ wave of 4 to 7 Hz, an alpha wave of 8 to 13 Hz, and a beta wave of 14 to 30 Hz.
  • the pre-processing is a denoising process.
  • the method of denoising processing is wavelet packet transform.
  • the EEG data of the patients with lumbar disc herniation after wavelet packet transformation are arranged according to a binary Gray code, wherein the nodes corresponding to each frequency band are as follows: the ⁇ wave corresponds to the wavelet node (6) , the sum of 1) and (6, 3); the ⁇ wave corresponds to the sum of the wavelet nodes (6, 4), (6, 6), (6, 7); the ⁇ wave corresponds to the wavelet node is (6, 8), The sum of (6,12), (6,13), (6,14), (6,15); the beta wave corresponds to the wavelet nodes as (6,10), (6,11), (6,16), (6,17), (6,18)(6,19), (6,22), (6,23), (6,24), (6,25), (6,26), (6, 27), (6, 28), (6, 29), (6, 30), (6, 31).
  • the characteristic value includes approximation of 14 channels before and after massage in patients with lumbar disc herniation
  • the characteristic values of the extracted lumbar disc herniation patients before and after the massage are statistically analyzed, and the changes of the EEG signals before and after the massage are analyzed to find the channel or rhythm of the difference, including the following. step:
  • the correlation between the channel or rhythm of the significant difference before and after the massage and the VAS pain level is analyzed, including the difference in the channel or rhythm of the difference in the lumbar disc herniation before and after the massage. Then, a correlation analysis was performed with the VAS pain level.
  • the present invention also provides an evaluation system for the effect of massage of a patient with lumbar disc herniation, including:
  • a pre-processing module for pre-processing the brain electrical data before and after massage of the collected lumbar disc herniation patients
  • a feature extraction module configured to extract characteristic values of brain electrical data before and after manipulation of the pre-treated lumbar disc herniation patient
  • the analysis module is used for statistical analysis of the characteristic values of the extracted lumbar disc herniation patients before and after massage, analyzing the changes of brain electrical signals before and after massage in patients with lumbar disc herniation, and finding out the significant channel or rhythm;
  • a comparison module was used to analyze the association of a channel or rhythm with a significant difference in VAS pain levels before and after manipulation in patients with lumbar disc herniation.
  • the invention provides a method and a system for evaluating the massage effect of lumbar disc herniation patients, and preprocesses the electroencephalogram data of the patients with lumbar disc herniation before and after the extraction, and extracts the electroencephalogram data of the pre-treated lumbar disc herniation patients before and after massage.
  • the eigenvalues were used to statistically analyze the eigenvalues of the patients with lumbar disc herniation before and after massage, and to analyze the changes of EEG signals before and after massage, to find out the significant channel or rhythm, and to analyze the patients with lumbar disc herniation before and after massage.
  • the correlation between the channel or rhythm of the significant difference and the VAS pain level, the evaluation method and system for the massage effect of the lumbar disc herniation patient obtaineds the characteristic value by performing a series of data processing on the collected EEG data, and performs statistics. Analysis, to find out the difference between before and after massage in patients with lumbar disc herniation, and then to carry out preliminary rehabilitation training evaluation of the massage effect, compared with the traditional imaging evaluation massage effect, it is non-invasive, convenient to measure in any place, and can reflect Out of motion anomalies that cannot be reflected by imaging Points, compared with the traditional score sheet to evaluate the effect of massage has the advantage of objective and accurate.
  • FIG. 1 is a step of an evaluation method for the effect of massage of a patient with lumbar disc herniation according to an embodiment. Flow chart.
  • FIG. 2 is a flow chart showing the steps of statistically analyzing the characteristic values of the extracted lumbar disc herniation patients before and after manipulation, analyzing the changes of the EEG signals before and after the massage, and finding the channels or rhythms with significant differences according to an embodiment of the present invention. .
  • FIG. 3 is a schematic diagram showing the difference in approximate entropy of four rhythms of ⁇ , ⁇ , ⁇ , and ⁇ of four rhythms of 14 channels before and after massage in a lumbar disc herniation patient according to an embodiment of the present invention.
  • FIG. 4 is a schematic diagram showing the difference in HHT marginal spectral entropy of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 5 is a schematic diagram showing the difference in approximate entropy of ⁇ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 6 is a schematic diagram showing the difference in approximate entropy of ⁇ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 7 is a schematic diagram showing the difference in approximate entropy of the ⁇ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 8 is a schematic diagram showing the difference in approximate entropy of ⁇ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 9 is a schematic diagram showing the difference in the HHT marginal spectral entropy of ⁇ of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 10 is a schematic diagram showing the difference in HHT marginal spectral entropy of ⁇ of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 11 is a schematic diagram showing the difference in the HHT marginal spectral entropy of ⁇ in 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 12 is a schematic diagram showing the difference in the HHT marginal spectral entropy of ⁇ in 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 13 is a schematic structural diagram of an evaluation system for the effect of massage of a patient with lumbar disc herniation according to an embodiment of the present invention.
  • an evaluation method 100 for the massage effect of a patient with lumbar disc herniation includes the following steps:
  • Step S110 collecting brain electrical data before and after massage in patients with lumbar disc herniation
  • the instrument for collecting brain electrical data of the patient with lumbar disc herniation is an EMOTIV EPOC brain electricity collecting instrument.
  • the electrode placement of the EMOTIV EPOC brain electricity collecting instrument adopts the international 10/20 system standard, and the electrode simultaneously records the 14-electrode EEG data, and the 14 channels of the 14-electrode are AF3, F7, F3, and FC5, respectively.
  • T7, P7, O1, O2, P8, T8, FC6, F4, F8, AF4 the electrode is an Ag/AGCI electrode, and the EEGIV EPOC brain electricity collecting instrument has an EEG sampling frequency of 128 Hz.
  • Step S120 preprocessing the electroencephalogram data of the lumbar disc herniation patient before and after massage
  • the pre-processing is a denoising process.
  • the method of the denoising process is a wavelet packet transform.
  • a person's spontaneous EEG signal has a frequency range of about 1 to 30 Hz and is divided into four bands, namely (1 to 3 Hz) ⁇ wave, 4 to 7 Hz ⁇ wave, and 8 to 13 Hz ⁇ . Wave, 14 ⁇ 30Hz ⁇ wave, so the data is wavelet packet transform to extract 1-30HZ EEG signal.
  • the Fourier transform theory is mostly used, which can have a good effect.
  • the spontaneous EEG signal has a frequency range of about 1 to 30 Hz and has a mutation.
  • the non-stationary signal of nature, and the effect of filtering by Fourier transform theory will become very poor, because the frequency bands of signal and noise overlap each other. Therefore, the wavelet packet transform of the present invention has obvious effect on non-stationary signal processing. It has a good local time-frequency nature and can perform very detailed processing of non-stationary signals in the time-frequency domain.
  • the sampling frequency of the EEG collecting instrument used in the present invention is 128 Hz, it can be known from the Nyquist law that the maximum frequency component in the signal does not exceed 64 Hz.
  • the sub-bands after wavelet packet decomposition are not arranged according to the frequency, but are arranged according to the binary Gray code.
  • ⁇ wave (1 ⁇ 3Hz) corresponds to the sum of wavelet nodes (6,1) and (6,3)
  • ⁇ wave (4 ⁇ 7Hz) corresponds to wavelet nodes (6,4), (6,6), (6,7)
  • ⁇ wave (8 ⁇ 13Hz) corresponds to the sum of wavelet nodes (6, 8), (6, 12), (6, 13), (6, 14), (6, 15)
  • ⁇ wave (14 ⁇ 30Hz Corresponding wavelet nodes (6, 10), (6, 11), (6, 16), (6, 17), (6, 18) (6, 19), (6, 22), (6, 23) , (6, 24), (6, 25), (6, 26), (6, 27), (6, 28), (6, 29), (6, 30), (6, 31) nodes with.
  • Step S130 extracting the pre- and post-operative lumbar disc herniation patient's brain electrical data before and after massage Value
  • the characteristic values include approximate entropy and HHT marginal spectral entropy characteristic values of 14 channels before and after massage in lumbar disc herniation patients and approximate entropy and HHT of 4 rhythms ( ⁇ , ⁇ , ⁇ and ⁇ ) of 14 channels Marginal spectral entropy eigenvalues.
  • the approximate entropy is a nonlinear dynamic parameter of metric sequence complexity and statistical quantification proposed by Pincus in 1991. It is derived from KS entropy and is suitable for the complexity analysis of short-term sequences. Approximate entropy is a complex Sexual analysis method, which does not need to coarse-grain the time series, and can achieve stable values with only a short data, and has some characteristics that other complexity parameters do not have, and is well applied in some fields.
  • Approximate entropy uses a non-negative number to represent the complexity of a time series, reflecting the rate of new information in the time series. The more complex the time series corresponds to the approximate entropy, the study shows that the approximate entropy can represent the change of human physiological state. It is especially suitable for analyzing non-stationary biological signals such as EEG signals.
  • the approximate entropy of the EEG sequence represents the probability of generating a new pattern in the EEG sequence. The greater the probability of generating a new pattern, the greater the complexity of the sequence and the larger the approximate entropy value.
  • the approximate entropy is defined as:
  • the present invention applies approximate entropy to four rhythms of 14 EEG signal channels and 14 EEG signal channels.
  • HHT method is a method for smoothing the signal.
  • HHT can accurately give the law of frequency variation with time in the signal, avoiding false frequencies, etc.
  • the redundancy phenomenon has clear physical meaning for dealing with nonlinear and non-stationary signals, and can obtain the amplitude-time-frequency distribution characteristics of the signal and is adaptive.
  • the HHT marginal spectral entropy is defined as:
  • the entropy value is normalized to 0 to 1, then there is
  • N is the length of the h(k) sequence.
  • Step S140 statistically analyzing the characteristic values of the extracted lumbar disc herniation patients before and after massage, analyzing the changes of the brain electrical signals before and after the massage, and finding the channels or rhythms with significant differences;
  • Step S141 analyzing the difference in approximate entropy of four rhythms ( ⁇ , ⁇ , ⁇ , and ⁇ ) of 14 channels before and after massage in patients with lumbar disc herniation;
  • FIG. 3 is a schematic diagram showing the difference in approximate entropy of four rhythms ( ⁇ , ⁇ , ⁇ , and ⁇ ) of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention, wherein, when p ⁇ 0.05 For significant differences, * in the graph indicates a significant difference.
  • Step S142 analyzing the HHT marginal spectrum of 14 channels before and after massage in patients with lumbar disc herniation Difference in entropy;
  • FIG. 4 is a schematic diagram showing the difference of HHT marginal spectral entropy of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • Step S143 analyzing the difference in approximate entropy of four rhythms ( ⁇ , ⁇ , ⁇ , and ⁇ ) of 14 channels before and after massage in patients with lumbar disc herniation;
  • FIG. 5 is a schematic diagram showing the difference in approximate entropy of ⁇ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 6 is a schematic diagram showing the difference in approximate entropy of ⁇ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 7 is a schematic diagram showing the difference in approximate entropy of the ⁇ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 8 Before and after massage of a patient with lumbar disc herniation according to an embodiment of the present invention.
  • Step S144 Analyze the difference in the HHT marginal spectral entropy of ⁇ , ⁇ , ⁇ , and ⁇ of the four rhythms of the 14 channels before and after massage in patients with lumbar disc herniation.
  • FIG. 9 is a schematic diagram showing the difference of ⁇ HHT marginal spectral entropy of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 10 is a schematic diagram showing the difference of HHT marginal spectral entropy of ⁇ of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 11 is a schematic diagram showing the difference of the HHT marginal spectral entropy of ⁇ in 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • FIG. 12 is a schematic diagram showing the difference of the HHT marginal spectral entropy of ⁇ in 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
  • Step S150 analyzing the channel or section of the lumbar disc herniation patient with significant difference before and after massage Correlation between the law and the VAS pain level.
  • the correlation between the channel or rhythm with significant difference before and after the massage and the VAS pain level is analyzed, including the value of the channel or rhythm of the significant difference before and after the massage of the lumbar disc herniation patient, and then with the VAS pain level Correlation analysis.
  • the channel or rhythm in which the significant difference is present before and after the massage of the lumbar disc herniation patient is poor (the value before the massage - the value after the massage)
  • the correlation analysis is performed with the VAS pain level.
  • FIG. 2 is the HHT marginal spectral entropy difference and VAS of the P8 channel before and after the massage according to the embodiment of the present invention.
  • Table 3 is the correlation detection result of the ⁇ rhythm HHT marginal spectral entropy difference and VAS of the AF3 channel before and after the massage provided by the embodiment of the present invention, as can be seen from Tables 1, 2 and 3, O2 and
  • FIG. 13 is a schematic structural diagram of an evaluation system 200 for a massage effect of a lumbar disc herniation patient according to an embodiment of the present invention, including: an acquisition module 210, a preprocessing module 220, a feature extraction module 230, an analysis module 240, and a comparison module. 250. among them:
  • the acquisition module 210 is configured to collect brain electrical data before and after massage of the lumbar disc herniation patient; the pre-processing module 220 is configured to pre-process the acquired electroencephalogram data of the lumbar disc herniation patient before and after massage; and the feature extraction module 230 is used for extracting the pre-processing
  • the characteristic value of the EEG data before and after massage in the patient with lumbar disc herniation; the analysis module 240 is used for extracting the characteristic values before and after the massage of the lumbar disc herniation patient
  • Statistical analysis was performed to analyze changes in EEG signals before and after massage in patients with lumbar disc herniation, to find out the channel or rhythm of difference; and Comparison Module 150 was used to analyze the channel or rhythm of significant differences between patients with lumbar disc herniation before and after massage. Correlation of VAS pain levels.
  • the invention provides a method and a system for evaluating the massage effect of lumbar disc herniation patients, and preprocesses the electroencephalogram data of the patients with lumbar disc herniation before and after the extraction, and extracts the electroencephalogram data of the pre-treated lumbar disc herniation patients before and after massage.
  • the eigenvalues were used to statistically analyze the eigenvalues of the patients with lumbar disc herniation before and after massage, and to analyze the changes of EEG signals before and after massage, to find out the different channels or rhythms, and to analyze the significantity of patients with lumbar disc herniation before and after massage.
  • the correlation between the channel or rhythm of the difference and the VAS pain level, the method and system for evaluating the massage effect of the lumbar disc herniation patient obtaineds characteristic values by performing a series of data processing on the collected EEG data, and performs statistical analysis. Find out the difference between before and after massage in patients with lumbar disc herniation, and then carry out preliminary rehabilitation training evaluation on the massage effect. Compared with the traditional imaging evaluation, it has non-invasive, convenient measurement in any place, and can reflect the image. The advantages of motion anomalies that cannot be reflected, Traditional score sheet to evaluate the effect of massage has advantages over objective and accurate.

Abstract

Disclosed are a method and system for assessing effectiveness of tui na on lumbar disc herniation. The method comprises: pre-processing EEG data acquired from a lumbar disc herniation patient before and after tui na treatment (S120); extracting characteristic values from the pre-processed EEG data (S130); performing statistical analysis on the extracted characteristic values and identifying channel or rhythm variances by analyzing changes in EEG signals before and after tui na (S140); and analyzing for correlation between channels or rhythms, as well as VAS pain levels, showing significant differences before and after tui na (S150). The method and system for assessing effectiveness of tui na on lumbar disc herniation can be used to obtain characteristic values by performing data processing on acquired EEG data so as to perform statistical analysis thereon and identify differences in a lumbar disc herniation patient before and after tui na, thereby enabling assessment of tui na effectiveness in preliminary rehabilitative training; the method is non-invasive and can be executed in any location, and has the advantage of being able to disclose abnormal movement characteristics that cannot be disclosed by imaging, and thus is relatively more objective and accurate.

Description

一种腰椎间盘突出症患者推拿效果的评估方法及系统Method and system for evaluating massage effect of lumbar disc herniation patients 技术领域Technical field
本发明涉及一种腰椎间盘突出症患者推拿效果的评估方法及系统。The invention relates to a method and a system for evaluating the massage effect of a patient with lumbar disc herniation.
背景技术Background technique
腰椎间盘突出症是骨科的常见病、多发病,是腰腿疼痛最常见的原因,给患者带来很大的痛苦,如工作能力、学习能力、生活质量下降,甚至失能残疾。临床上对于非手术指征的LDH患者使用的保守方法种类丰富,传统中医又有着独到见解和办法,如手法推拿、内服中药方剂、外用中药膏剂、针灸等,都已成为被医生、患者接受的好办法。Lumbar disc herniation is a common and frequently-occurring disease in orthopedics. It is the most common cause of low back pain. It causes great pain to patients, such as work ability, learning ability, quality of life, and even disability. Clinically, there are a variety of conservative methods for non-surgical indications of LDH patients. Traditional Chinese medicine has unique insights and methods, such as manual massage, oral Chinese medicine prescription, topical Chinese medicine ointment, acupuncture, etc., which have been accepted by doctors and patients. good idea.
在腰椎间盘突出症非手术疗法中,推拿是一项重要的治疗方法,推拿具有温通经络、缓解肌肉痉挛、放松止痛等作用,手法推拿能够矫正发生位移的软组织或脊柱小关节的解剖形态和位置,令失常的力线恢复正常,调整内外平衡,缓解临床出现的疼痛麻木等症状改善血液循环,增强肌力,改善韧带的弹性并消除炎症脊髓外间接推拿摩揉擦等手法能够牵动脊髓和神经根产生摩擦,期待改善微循环,促进水肿洗手及松解粘连的作用,是受压神经得到修复,功能障碍得到缓解和消失。In the non-surgical treatment of lumbar disc herniation, massage is an important treatment. The massage has the functions of warming meridians, relieving muscle spasm, relaxing pain, etc. The manipulation can correct the anatomy of the soft tissue or the facet joint of the displacement. Position, make the abnormal line of force return to normal, adjust the internal and external balance, relieve the symptoms of clinical pain, numbness and other symptoms to improve blood circulation, enhance muscle strength, improve the elasticity of the ligament and eliminate inflammation. Indirect inhalation of the spinal cord and other methods can affect the spinal cord and The nerve roots produce friction, and it is expected to improve the microcirculation, promote the function of edema washing and loosening the adhesion, and the nerves are repaired, and the dysfunction is alleviated and disappeared.
目前针对腰椎间盘突出症患者推拿效果最常用的评估方法有影像学评估法和评分表评估法:At present, the most commonly used evaluation methods for the treatment of lumbar disc herniation are imaging evaluation and scoring evaluation:
(1)影像学评估法,影像学评估方法包括X线、计算机断层扫描(CT)及磁共振扫描(MRI)等,X线是最早也是最基本的测量方法,分析腰椎的过屈过伸侧位片是临床上常用的方法,此方法简单易行,操作简单;CT可以获得腰部不同仰卧位上的数据,发现解剖上的改变,利用数据进行三维重建和测量;MRI可以获取矢状面、冠状面、横断面以及任何方向断面的图像,能够 直接三维重建显示,该方法采用的是平卧位椎体拍摄。腰椎间盘突出症患者表现在脊柱损伤,往往显示脊柱运动的异常,以上影像学放射性检查方法可能不易显示异常。(1) Imaging evaluation method, imaging evaluation methods include X-ray, computed tomography (CT) and magnetic resonance imaging (MRI). X-ray is the earliest and most basic measurement method for analyzing the hyperflexed side of the lumbar spine. The slice is a commonly used method in clinical practice. This method is simple and easy to operate. CT can obtain data on different supine positions in the waist, find anatomical changes, use data for 3D reconstruction and measurement; MRI can obtain sagittal plane, Images of coronal, cross-sectional, and cross-sections in any direction, capable of Direct 3D reconstruction showed that the method used a supine vertebral body. Patients with lumbar disc herniation are manifested in spinal injury and often show abnormalities in spinal motion. The above imaging radiological examination methods may not be easy to show abnormalities.
(2)评分表评估法包括疼痛视觉模拟评分量表、功能障碍指标问卷表、腰椎功能评分量表等方法。疼痛视觉模拟评分量表,该法比较灵敏,有可比性,具体做法是:在纸上面划一条10cm的横线,横线的一端为0,表示无痛,另一端为10,表示剧痛,中间部分表示不同程度的疼痛,让病人根据自我感觉在横线上划一记号,表示疼痛的程度。功能障碍指标问卷表是由10个问题组成,包括疼痛的强度、生活自理、提物、步行、坐位、站立、干扰睡眠、性生活、社会生活、旅游等10个方面的情况,每个问题6个选项,每个问题的最高得分为5分,选择第一个选项得分为0分,依次选择最后一个选项得分为5分,假如有10个问题都做了问答,记分方法是:实际得分/50(最高可能得分)×100%,假如有一个问题没有回答,则记分方法是:实际得分/45(最高可能得分)×100%,如越高表明功能障碍越严重。(2) The score assessment method includes the pain visual analog scale scale, the dysfunction index questionnaire, and the lumbar spine function score scale. Pain visual analogue scale scale, the method is more sensitive and comparable. The specific method is: draw a 10cm horizontal line on the paper, one end of the horizontal line is 0, indicating no pain, the other end is 10, indicating severe pain. The middle part indicates different degrees of pain, allowing the patient to draw a mark on the horizontal line according to the feeling of self, indicating the degree of pain. The dysfunction index questionnaire consists of 10 questions, including the intensity of pain, self-care, walking, walking, sitting, standing, disturbing sleep, sex life, social life, tourism, etc., each question 6 Options, the highest score for each question is 5 points, the first option is 0 points, and the last option is 5 points. If there are 10 questions, the scoring method is: actual score / 50 (highest possible score) × 100%, if there is a question that is not answered, the scoring method is: actual score / 45 (highest possible score) × 100%, if the higher indicates that the dysfunction is more serious.
但是,这些评分方法主要依据人的主观感觉进行评估,具有一定的局限性和误差性。However, these scoring methods are mainly based on the subjective feelings of people, which have certain limitations and errors.
发明内容Summary of the invention
基于此,有必要针对现有技术存在的缺陷,提供一种操作简单、科学客观的腰椎间盘突出症患者推拿效果的评估方法及系统。Based on this, it is necessary to provide a method and system for evaluating the massage effect of patients with lumbar disc herniation, which is simple and scientific and objective, in view of the defects of the prior art.
为实现上述目的,本发明采用下述技术方案:In order to achieve the above object, the present invention adopts the following technical solutions:
一种腰椎间盘突出症患者推拿效果的评估方法,包括下述步骤:A method for evaluating the effect of massage of a patient with lumbar disc herniation includes the following steps:
采集腰椎间盘突出症患者推拿前后脑电数据; Collecting EEG data before and after massage in patients with lumbar disc herniation;
对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理;Pretreatment of the acquired EEG data before and after massage in patients with lumbar disc herniation;
提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值;Extracting the characteristic values of the EEG data before and after manipulation of the pre-treated lumbar disc herniation patients;
将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,分析推拿前后脑电信号的变化,找出有显著性差异的通道或节律;及The characteristic values of the extracted lumbar disc herniation patients before and after massage were statistically analyzed, and the changes of EEG signals before and after massage were analyzed to find out the channels or rhythms with significant differences;
分析腰椎间盘突出症患者推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性。To analyze the correlation between the channel or rhythm of patients with lumbar disc herniation before and after massage and the level of VAS pain.
在一些较佳的实施例在中,在采集腰椎间盘突出症患者推拿前后脑电数据的步骤中,采集腰椎间盘突出症患者脑电数据的仪器为EMOTIV EPOC脑电采集仪。In some preferred embodiments, in the step of collecting brain electrical data before and after massage of the lumbar disc herniation patient, the instrument for collecting electroencephalogram data of the patient with lumbar disc herniation is an EMOTIV EPOC brain electricity collecting instrument.
在一些较佳的实施例在中,所述EMOTIV EPOC脑电采集仪的电极放置采用国际10/20系统标准,所述电极同时记录14导电极EEG数据,14导电极的14个通道分别为AF3,F7,F3,FC5,T7,P7,O1,O2,P8,T8,FC6,F4,F8,AF4,所述电极为Ag/AGCI电极,所述EMOTIV EPOC脑电采集仪的脑电采样频率为128Hz,所述腰椎间盘突出症患者脑电数据的波段包括1~3Hz的δ波、4~7Hz的θ波、8~13Hz的α波、14~30Hz的β波。In some preferred embodiments, the electrode placement of the EMOTIV EPOC EEG is performed using the international 10/20 system standard, the electrode simultaneously recording 14 conductive EEG data, and the 14 channels of the 14 conductive electrodes are respectively AF3. , F7, F3, FC5, T7, P7, O1, O2, P8, T8, FC6, F4, F8, AF4, the electrode is an Ag/AGCI electrode, and the EEG sampling frequency of the EMOTIV EPOC brain electricity collecting instrument is At 128 Hz, the band of the electroencephalogram data of the patient with lumbar disc herniation includes a δ wave of 1 to 3 Hz, a θ wave of 4 to 7 Hz, an alpha wave of 8 to 13 Hz, and a beta wave of 14 to 30 Hz.
在一些较佳的实施例在中,在对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理的步骤中,所述预处理为去噪处理。In some preferred embodiments, in the step of pre-treating the electroencephalogram data before and after manipulation of the acquired lumbar disc herniation patient, the pre-processing is a denoising process.
在一些较佳的实施例在中,所述去噪处理的方法为小波包变换。In some preferred embodiments, the method of denoising processing is wavelet packet transform.
在一些较佳的实施例在中,经小波包变换后的腰椎间盘突出症患者推拿前后脑电数据按照二进制格雷码排列的,其中各个频段对应的节点情况如下:δ波对应小波节点为(6,1)和(6,3)之和;θ波对应小波节点为(6,4)、(6,6)、(6,7)之和;α波对应小波节点为(6,8)、(6,12)、(6,13)、(6,14)、(6,15)之和;β波对应小波节点为(6,10)、(6,11)、(6,16)、 (6,17)、(6,18)(6,19)、(6,22)、(6,23)、(6,24)、(6,25)、(6,26)、(6,27)、(6,28)、(6,29)、(6,30)、(6,31)之和。In some preferred embodiments, the EEG data of the patients with lumbar disc herniation after wavelet packet transformation are arranged according to a binary Gray code, wherein the nodes corresponding to each frequency band are as follows: the δ wave corresponds to the wavelet node (6) , the sum of 1) and (6, 3); the θ wave corresponds to the sum of the wavelet nodes (6, 4), (6, 6), (6, 7); the α wave corresponds to the wavelet node is (6, 8), The sum of (6,12), (6,13), (6,14), (6,15); the beta wave corresponds to the wavelet nodes as (6,10), (6,11), (6,16), (6,17), (6,18)(6,19), (6,22), (6,23), (6,24), (6,25), (6,26), (6, 27), (6, 28), (6, 29), (6, 30), (6, 31).
在一些较佳的实施例在中,在提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值的步骤中,所述特征值包括腰椎间盘突出症患者推拿前后14个通道的近似熵和HHT边际谱熵特征值及14个通道的4个节律(δ、θ、α和β)的近似熵和HHT边际谱熵特征值。In some preferred embodiments, in the step of extracting characteristic values of EEG data before and after manipulation of the pre-treated lumbar disc herniation patient, the characteristic value includes approximation of 14 channels before and after massage in patients with lumbar disc herniation The entropy and HHT marginal spectral entropy eigenvalues and the approximate entropy of the four rhythms (δ, θ, α, and β) of 14 channels and the HHT marginal spectral entropy eigenvalues.
在一些较佳的实施例在中,其中,将提取的推拿前后腰椎间盘突出症患者的特征值进行统计学分析,分析推拿前后脑电信号的变化,找出差异的通道或节律,包括下述步骤:In some preferred embodiments, the characteristic values of the extracted lumbar disc herniation patients before and after the massage are statistically analyzed, and the changes of the EEG signals before and after the massage are analyzed to find the channel or rhythm of the difference, including the following. step:
分析腰椎间盘突出症患者推拿前后14个通道的4个节律(δ、θ、α和β)的近似熵的差异性;To analyze the difference in the approximate entropy of the four rhythms (δ, θ, α, and β) of 14 channels before and after massage in patients with lumbar disc herniation;
分析腰椎间盘突出症患者推拿前后14个通道的HHT边际谱熵的差异性;To analyze the difference of HHT marginal spectral entropy in 14 channels before and after massage in patients with lumbar disc herniation;
分析腰椎间盘突出症患者推拿前后14个通道的4个节律(δ、θ、α和β)的近似熵的差异性;To analyze the difference in the approximate entropy of the four rhythms (δ, θ, α, and β) of 14 channels before and after massage in patients with lumbar disc herniation;
分析腰椎间盘突出症患者推拿前后14个通道的4个节律(δ、θ、α和β)的HHT边际谱熵的差异性。The differences in HHT marginal spectral entropy of the four rhythms (δ, θ, α, and β) of 14 channels before and after massage in patients with lumbar disc herniation were analyzed.
在一些较佳的实施例在中,其中,分析推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性,包括将腰椎间盘突出症患者推拿前后出现差异的通道或节律的值做差,然后与VAS疼痛等级作相关性分析。In some preferred embodiments, wherein the correlation between the channel or rhythm of the significant difference before and after the massage and the VAS pain level is analyzed, including the difference in the channel or rhythm of the difference in the lumbar disc herniation before and after the massage. Then, a correlation analysis was performed with the VAS pain level.
另外,本发明还提供了一种腰椎间盘突出症患者推拿效果的评估系统,包括:In addition, the present invention also provides an evaluation system for the effect of massage of a patient with lumbar disc herniation, including:
采集模块,用于采集腰椎间盘突出症患者推拿前后脑电数据; An acquisition module for collecting brain electrical data before and after massage in patients with lumbar disc herniation;
预处理模块,用于对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理;a pre-processing module for pre-processing the brain electrical data before and after massage of the collected lumbar disc herniation patients;
特征提取模块,用于提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值;a feature extraction module, configured to extract characteristic values of brain electrical data before and after manipulation of the pre-treated lumbar disc herniation patient;
分析模块,用于将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,分析腰椎间盘突出症患者推拿前后脑电信号的变化,找出差异性显著的通道或节律;及The analysis module is used for statistical analysis of the characteristic values of the extracted lumbar disc herniation patients before and after massage, analyzing the changes of brain electrical signals before and after massage in patients with lumbar disc herniation, and finding out the significant channel or rhythm;
比较模块,用于分析腰椎间盘突出症患者推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性。A comparison module was used to analyze the association of a channel or rhythm with a significant difference in VAS pain levels before and after manipulation in patients with lumbar disc herniation.
本发明采用上述技术方案的有益效果在于:The beneficial effects of the above technical solution of the present invention are as follows:
本发明提供的腰椎间盘突出症患者推拿效果的评估方法及系统,对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理,提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值,将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,并分析推拿前后脑电信号的变化,找出差异性显著的通道或节律,分析腰椎间盘突出症患者推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性,本发明提供的腰椎间盘突出症患者推拿效果的评估方法及系统通过对采集的脑电数据进行一系列数据处理得到特征值,进行统计学分析,找出腰椎间盘突出症患者推拿前后的差异性,进而对推拿效果进行初步的康复训练评估,与传统的影像学评估推拿效果相比,它具有无创,方便在任何场所测量,以及可以反映出影像学不能反映的运动异常特征的优点,与传统的评分表评估推拿效果相比具有客观准确的优点。The invention provides a method and a system for evaluating the massage effect of lumbar disc herniation patients, and preprocesses the electroencephalogram data of the patients with lumbar disc herniation before and after the extraction, and extracts the electroencephalogram data of the pre-treated lumbar disc herniation patients before and after massage. The eigenvalues were used to statistically analyze the eigenvalues of the patients with lumbar disc herniation before and after massage, and to analyze the changes of EEG signals before and after massage, to find out the significant channel or rhythm, and to analyze the patients with lumbar disc herniation before and after massage. The correlation between the channel or rhythm of the significant difference and the VAS pain level, the evaluation method and system for the massage effect of the lumbar disc herniation patient provided by the present invention obtains the characteristic value by performing a series of data processing on the collected EEG data, and performs statistics. Analysis, to find out the difference between before and after massage in patients with lumbar disc herniation, and then to carry out preliminary rehabilitation training evaluation of the massage effect, compared with the traditional imaging evaluation massage effect, it is non-invasive, convenient to measure in any place, and can reflect Out of motion anomalies that cannot be reflected by imaging Points, compared with the traditional score sheet to evaluate the effect of massage has the advantage of objective and accurate.
附图说明DRAWINGS
图1为一实施方式提供的腰椎间盘突出症患者推拿效果的评估方法的步 骤流程图。1 is a step of an evaluation method for the effect of massage of a patient with lumbar disc herniation according to an embodiment. Flow chart.
图2为本发明一实施例提供的将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,分析推拿前后脑电信号的变化,找出差异性显著的通道或节律的步骤流程图。FIG. 2 is a flow chart showing the steps of statistically analyzing the characteristic values of the extracted lumbar disc herniation patients before and after manipulation, analyzing the changes of the EEG signals before and after the massage, and finding the channels or rhythms with significant differences according to an embodiment of the present invention. .
图3为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的4个节律的δ、θ、α和β四个节律的近似熵的差异性示意图。FIG. 3 is a schematic diagram showing the difference in approximate entropy of four rhythms of δ, θ, α, and β of four rhythms of 14 channels before and after massage in a lumbar disc herniation patient according to an embodiment of the present invention.
图4为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的HHT边际谱熵的差异性示意图。4 is a schematic diagram showing the difference in HHT marginal spectral entropy of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图5为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的δ节律的近似熵的差异性示意图。FIG. 5 is a schematic diagram showing the difference in approximate entropy of δ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图6为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的θ节律的近似熵的差异性示意图。FIG. 6 is a schematic diagram showing the difference in approximate entropy of θ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图7为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的α节律的近似熵的差异性示意图。FIG. 7 is a schematic diagram showing the difference in approximate entropy of the α rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图8为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的β节律的近似熵的差异性示意图。FIG. 8 is a schematic diagram showing the difference in approximate entropy of β rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图9为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的δ的HHT边际谱熵的差异性示意图。FIG. 9 is a schematic diagram showing the difference in the HHT marginal spectral entropy of δ of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图10为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的θ的HHT边际谱熵的差异性示意图。FIG. 10 is a schematic diagram showing the difference in HHT marginal spectral entropy of θ of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图11为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的α的HHT边际谱熵的差异性示意图。 FIG. 11 is a schematic diagram showing the difference in the HHT marginal spectral entropy of α in 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图12为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的β的HHT边际谱熵的差异性示意图。FIG. 12 is a schematic diagram showing the difference in the HHT marginal spectral entropy of β in 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
图13为本发明一实施例提供的腰椎间盘突出症患者推拿效果的评估系统的结构示意图。FIG. 13 is a schematic structural diagram of an evaluation system for the effect of massage of a patient with lumbar disc herniation according to an embodiment of the present invention.
具体实施方式detailed description
为了便于理解本发明,下面将参照相关附图对本发明进行更全面的描述。附图中给出了本发明的较佳的实施例。但是,本发明可以以许多不同的形式来实现,并不限于本文所描述的实施例。相反地,提供这些实施例的目的是使对本发明的公开内容的理解更加透彻全面。In order to facilitate the understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. Preferred embodiments of the invention are shown in the drawings. However, the invention may be embodied in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that the understanding of the present disclosure will be more fully understood.
除非另有定义,本文所使用的所有的技术和科学术语与属于本发明的技术领域的技术人员通常理解的含义相同。本文中在本发明的说明书中所使用的术语只是为了描述具体的实施例的目的,不是旨在于限制本发明。All technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, unless otherwise defined. The terminology used in the description of the present invention is for the purpose of describing particular embodiments and is not intended to limit the invention.
如图1所示,一实施方式的腰椎间盘突出症患者推拿效果的评估方法100,包括下述步骤:As shown in FIG. 1, an evaluation method 100 for the massage effect of a patient with lumbar disc herniation according to an embodiment includes the following steps:
步骤S110,采集腰椎间盘突出症患者推拿前后脑电数据;Step S110, collecting brain electrical data before and after massage in patients with lumbar disc herniation;
优选地,在采集腰椎间盘突出症患者推拿前后脑电数据的步骤中,采集腰椎间盘突出症患者脑电数据的仪器为EMOTIV EPOC脑电采集仪。Preferably, in the step of collecting brain electrical data before and after massage of the lumbar disc herniation patient, the instrument for collecting brain electrical data of the patient with lumbar disc herniation is an EMOTIV EPOC brain electricity collecting instrument.
具体地,所述EMOTIV EPOC脑电采集仪的电极放置采用国际10/20系统标准,所述电极同时记录14导电极EEG数据,14导电极的14个通道分别为AF3,F7,F3,FC5,T7,P7,O1,O2,P8,T8,FC6,F4,F8,AF4,所述电极为Ag/AGCI电极,所述EMOTIV EPOC脑电采集仪的脑电采样频率为128Hz。 Specifically, the electrode placement of the EMOTIV EPOC brain electricity collecting instrument adopts the international 10/20 system standard, and the electrode simultaneously records the 14-electrode EEG data, and the 14 channels of the 14-electrode are AF3, F7, F3, and FC5, respectively. T7, P7, O1, O2, P8, T8, FC6, F4, F8, AF4, the electrode is an Ag/AGCI electrode, and the EEGIV EPOC brain electricity collecting instrument has an EEG sampling frequency of 128 Hz.
步骤S120,对所述腰椎间盘突出症患者推拿前后脑电数据进行预处理;Step S120, preprocessing the electroencephalogram data of the lumbar disc herniation patient before and after massage;
优选地,在对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理的步骤中,所述预处理为去噪处理。Preferably, in the step of pre-treating the electroencephalogram data before and after the massage of the collected lumbar disc herniation patient, the pre-processing is a denoising process.
进一步地,所述去噪处理的方法为小波包变换。Further, the method of the denoising process is a wavelet packet transform.
可以理解,人的自发脑电信号,其波动的频率范围大概在1~30Hz之间,分成四个波段,即(1~3Hz)的δ波、4~7Hz的θ波、8~13Hz的α波、14~30Hz的β波,所以将数据进行小波包变换提取出1-30HZ的脑电信号。It can be understood that a person's spontaneous EEG signal has a frequency range of about 1 to 30 Hz and is divided into four bands, namely (1 to 3 Hz) δ wave, 4 to 7 Hz θ wave, and 8 to 13 Hz α. Wave, 14 ~ 30Hz β wave, so the data is wavelet packet transform to extract 1-30HZ EEG signal.
可以理解,对于传统信号去噪方法,大都采取傅里叶变换理论,就能够具有很好的效果,但是,人的自发脑电信号,其波动的频率范围大概在1~30Hz之间,具有突变性质的非平稳信号,而此时采取傅里叶变换理论进行滤波其效果将会变得很差,因为信号与噪声的频带相互重叠,因此本发明采用小波包变换对非平稳信号处理效果比较明显,其具有很好的局部时频性质,可以将非平稳信号在时频域中进行很细致的处理。It can be understood that for the traditional signal denoising method, the Fourier transform theory is mostly used, which can have a good effect. However, the spontaneous EEG signal has a frequency range of about 1 to 30 Hz and has a mutation. The non-stationary signal of nature, and the effect of filtering by Fourier transform theory will become very poor, because the frequency bands of signal and noise overlap each other. Therefore, the wavelet packet transform of the present invention has obvious effect on non-stationary signal processing. It has a good local time-frequency nature and can perform very detailed processing of non-stationary signals in the time-frequency domain.
可以理解,由于本发明采用的脑电采集仪器采样频率为128Hz,由奈奎斯特定律可知,信号中的最大频率分量不会超过64Hz,本发明对脑电信号进行6层小波包分解,那么得到的频率分辨率为64/26=1Hz,然而小波包分解后的各个子频带并不是按照频率的大小排列的,而是按照二进制格雷码排列的,其中各个频段对应的节点情况如下:δ波(1~3Hz)对应小波节点(6,1)和(6,3)之和;θ波(4~7Hz)对应小波节点(6,4)、(6,6)、(6,7)之和;α波(8~13Hz)对应小波节点(6,8)、(6,12)、(6,13)、(6,14)、(6,15)之和;β波(14~30Hz)对应小波节点(6,10)、(6,11)、(6,16)、(6,17)、(6,18)(6,19)、(6,22)、(6,23)、(6,24)、(6,25)、(6,26)、(6,27)、(6,28)、(6,29)、(6,30)、(6,31)节点之和。It can be understood that, since the sampling frequency of the EEG collecting instrument used in the present invention is 128 Hz, it can be known from the Nyquist law that the maximum frequency component in the signal does not exceed 64 Hz. The present invention performs 6-layer wavelet packet decomposition on the EEG signal, and then obtains The frequency resolution is 64/2 6 =1 Hz. However, the sub-bands after wavelet packet decomposition are not arranged according to the frequency, but are arranged according to the binary Gray code. The corresponding nodes of each frequency band are as follows: δ wave (1~3Hz) corresponds to the sum of wavelet nodes (6,1) and (6,3); θ wave (4~7Hz) corresponds to wavelet nodes (6,4), (6,6), (6,7) And; α wave (8 ~ 13Hz) corresponds to the sum of wavelet nodes (6, 8), (6, 12), (6, 13), (6, 14), (6, 15); β wave (14 ~ 30Hz Corresponding wavelet nodes (6, 10), (6, 11), (6, 16), (6, 17), (6, 18) (6, 19), (6, 22), (6, 23) , (6, 24), (6, 25), (6, 26), (6, 27), (6, 28), (6, 29), (6, 30), (6, 31) nodes with.
步骤S130,提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特 征值;Step S130, extracting the pre- and post-operative lumbar disc herniation patient's brain electrical data before and after massage Value
优选地,所述特征值包括腰椎间盘突出症患者推拿前后14个通道的近似熵和HHT边际谱熵特征值及14个通道的4个节律(δ、θ、α和β)的近似熵和HHT边际谱熵特征值。Preferably, the characteristic values include approximate entropy and HHT marginal spectral entropy characteristic values of 14 channels before and after massage in lumbar disc herniation patients and approximate entropy and HHT of 4 rhythms (δ, θ, α and β) of 14 channels Marginal spectral entropy eigenvalues.
可以理解,近似熵是Pincus于1991年提出的一种度量序列复杂性和统计量化的非线性动力学参数,它源于KS熵,适用于短时序列的复杂性分析,近似熵是一种复杂性分析方法,它无需对时间序列粗粒化,且只需很短的数据即可达到稳定的值,具有一些其他复杂性参数所不具备的特点,在一些领域得到很好的应用。It can be understood that the approximate entropy is a nonlinear dynamic parameter of metric sequence complexity and statistical quantification proposed by Pincus in 1991. It is derived from KS entropy and is suitable for the complexity analysis of short-term sequences. Approximate entropy is a complex Sexual analysis method, which does not need to coarse-grain the time series, and can achieve stable values with only a short data, and has some characteristics that other complexity parameters do not have, and is well applied in some fields.
近似熵利用一个非负数来表示一个时间序列的复杂性,反映时间序列中新信息发生率,越复杂的时间序列对应的近似熵越大,研究表明近似熵能够表征人的生理状态的变化情况,特别适用于分析脑电信号等非平稳的生物信号。EEG序列的近似熵表现了EEG序列中产生新模式的概率大小,产生新模式概率越大,序列的复杂性越大,近似熵值越大。近似熵的定义为:Approximate entropy uses a non-negative number to represent the complexity of a time series, reflecting the rate of new information in the time series. The more complex the time series corresponds to the approximate entropy, the study shows that the approximate entropy can represent the change of human physiological state. It is especially suitable for analyzing non-stationary biological signals such as EEG signals. The approximate entropy of the EEG sequence represents the probability of generating a new pattern in the EEG sequence. The greater the probability of generating a new pattern, the greater the complexity of the sequence and the larger the approximate entropy value. The approximate entropy is defined as:
ApEn(m,r,N)=φm(r)-φm+1(r)ApEn(m,r,N)=φ m (r)-φ m+1 (r)
本发明将近似熵应用于14个脑电信号通道和14个脑电信号通道的四个节律,在本发明中,当参数m=2,r=0.1,N=1024的时候,近似熵结果有效。The present invention applies approximate entropy to four rhythms of 14 EEG signal channels and 14 EEG signal channels. In the present invention, when the parameters m=2, r=0.1, N=1024, the approximate entropy result is effective. .
希尔伯特黄变换(Hilbert-Huang Transform,简称HHT)方法,HHT方法是一种对信号进行平稳化处理的方法,HHT能够精确的给出信号中频率随时间变化的规律,避免虚假频率等冗余现象,对于处理非线性、非平稳信号有着清晰的物理意义,能够得到信号的振幅-时间-频率分布特征,且具有自适应性。Hilbert-Huang Transform (HHT) method, HHT method is a method for smoothing the signal. HHT can accurately give the law of frequency variation with time in the signal, avoiding false frequencies, etc. The redundancy phenomenon has clear physical meaning for dealing with nonlinear and non-stationary signals, and can obtain the amplitude-time-frequency distribution characteristics of the signal and is adaptive.
HHT边际谱熵定义为: The HHT marginal spectral entropy is defined as:
Figure PCTCN2017077701-appb-000001
Figure PCTCN2017077701-appb-000001
其中,pk=h(k)/∑h(k),表示第k个频率对应幅值出现的概率。Where p k =h(k)/∑h(k) represents the probability that the kth frequency corresponds to the amplitude.
熵值归一化为0~1,则有The entropy value is normalized to 0 to 1, then there is
Figure PCTCN2017077701-appb-000002
Figure PCTCN2017077701-appb-000002
公式中N是h(k)序列的长度。In the formula, N is the length of the h(k) sequence.
本发明将HHT边际谱熵应用于14个脑电通道和14个脑电通道的四个节律,其中根据实验硬件和信号的特点选择信号的长度N=1024。The present invention applies HHT marginal spectral entropy to four rhythms of 14 EEG channels and 14 EEG channels, wherein the length of the signal is selected to be N=1024 according to the characteristics of the experimental hardware and signals.
步骤S140,将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,分析推拿前后脑电信号的变化,找出差异性显著的通道或节律;Step S140, statistically analyzing the characteristic values of the extracted lumbar disc herniation patients before and after massage, analyzing the changes of the brain electrical signals before and after the massage, and finding the channels or rhythms with significant differences;
请参阅图2,将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,分析推拿前后脑电信号的变化,找出差异的通道或节律,包括下述步骤:Referring to FIG. 2, statistical analysis is performed on the characteristic values of the extracted lumbar disc herniation patients before and after massage, and the changes of the EEG signals before and after the massage are analyzed to find the channel or rhythm of the difference, including the following steps:
步骤S141:分析腰椎间盘突出症患者推拿前后14个通道的4个节律(δ、θ、α和β)的近似熵的差异性;Step S141: analyzing the difference in approximate entropy of four rhythms (δ, θ, α, and β) of 14 channels before and after massage in patients with lumbar disc herniation;
请参阅图3,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的4个节律(δ、θ、α和β)的近似熵的差异性示意图,其中,当p<0.05为显著性差异,图中*表示显著性差异。Please refer to FIG. 3 , which is a schematic diagram showing the difference in approximate entropy of four rhythms (δ, θ, α, and β) of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention, wherein, when p<0.05 For significant differences, * in the graph indicates a significant difference.
图3中可以看出,通道F3、FC5、T7、P7、O2、P8、T8、FC6有显著性差异(假设检验中的p值分别为:p=0.032、p=0.026、p=0.036、p=0.02、p=0.032、p=0.007、p=0.02、p=0.021)。As can be seen in Figure 3, the channels F3, FC5, T7, P7, O2, P8, T8, and FC6 are significantly different (the p values in the hypothesis test are: p=0.032, p=0.026, p=0.036, p = 0.02, p = 0.032, p = 0.007, p = 0.02, p = 0.021).
步骤S142:分析腰椎间盘突出症患者推拿前后14个通道的HHT边际谱 熵的差异性;Step S142: analyzing the HHT marginal spectrum of 14 channels before and after massage in patients with lumbar disc herniation Difference in entropy;
请参阅图4,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的HHT边际谱熵的差异性示意图。Please refer to FIG. 4 , which is a schematic diagram showing the difference of HHT marginal spectral entropy of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
从图4中可以看出,通道F7、FC5、P7、O2、P8、FC6有显著性差异(假设检验中的p值分别为:p=0.017、p=0.048、p=0.001、p=0.008、p=0.014、p=0.001)。It can be seen from Fig. 4 that the channels F7, FC5, P7, O2, P8, and FC6 are significantly different (the p values in the hypothesis test are: p=0.017, p=0.048, p=0.001, p=0.008, p = 0.014, p = 0.001).
步骤S143:分析腰椎间盘突出症患者推拿前后14个通道的4个节律(δ、θ、α和β)的近似熵的差异性;Step S143: analyzing the difference in approximate entropy of four rhythms (δ, θ, α, and β) of 14 channels before and after massage in patients with lumbar disc herniation;
请参阅图5,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的δ节律的近似熵的差异性示意图。Please refer to FIG. 5 , which is a schematic diagram showing the difference in approximate entropy of δ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
从图5中可以看出,在δ节律中,通道F3、P7、O2、P8、FC6、F4有显著性差异(假设检验中的p值分别为p=0.037、p=0.038、p=0.005、p=0.012、p=0.009、p=0.029)。It can be seen from Fig. 5 that in the δ rhythm, the channels F3, P7, O2, P8, FC6, and F4 are significantly different (the p values in the hypothesis test are p=0.037, p=0.038, p=0.005, respectively). p = 0.012, p = 0.909, p = 0.029).
请参阅图6,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的θ节律的近似熵的差异性示意图。Please refer to FIG. 6 , which is a schematic diagram showing the difference in approximate entropy of θ rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
从图6中可以看出,在θ节律中,通道O2有显著性差异,(假设检验中的P值:p=0.002)。As can be seen from Fig. 6, in the θ rhythm, there is a significant difference in the channel O2 (assuming a P value in the test: p = 0.002).
请参阅图7,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的α节律的近似熵的差异性示意图。Please refer to FIG. 7 , which is a schematic diagram showing the difference in approximate entropy of the α rhythm of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
从图7中可以看出,在α节律中,通道AF3、F3、FC5、P7、O1、P8、T8、FC6有显著性差异(假设检验中的P值分别为:p=0.009、p=0.002、p=0.001、p=0.011、p=0.006、p=0.033、p=0.011、p=0.014)。It can be seen from Fig. 7 that in the α rhythm, the channels AF3, F3, FC5, P7, O1, P8, T8, and FC6 are significantly different (the P values in the hypothesis test are: p=0.009, p=0.002, respectively). , p = 0.001, p = 0.011, p = 0.006, p = 0.033, p = 0.011, p = 0.014).
请参阅图8,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14 个通道的β节律的近似熵的差异性示意图。Please refer to FIG. 8 , before and after massage of a patient with lumbar disc herniation according to an embodiment of the present invention. A schematic representation of the difference in the approximate entropy of the beta rhythm of a channel.
从图8中可以看出,在β节律中,没有发现显著性差异的通道。As can be seen from Fig. 8, in the beta rhythm, no significant difference was found in the channel.
步骤S144:分析腰椎间盘突出症患者推拿前后14个通道的4个节律的δ、θ、α和β的HHT边际谱熵的差异性。Step S144: Analyze the difference in the HHT marginal spectral entropy of δ, θ, α, and β of the four rhythms of the 14 channels before and after massage in patients with lumbar disc herniation.
请参阅图9,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的δ的HHT边际谱熵的差异性示意图。Please refer to FIG. 9 , which is a schematic diagram showing the difference of δ HHT marginal spectral entropy of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
从图9中可以看出,在δ节律中,在通道AF3中有显著性差异,(假设检验中的p值为:p=0.024)。As can be seen from Fig. 9, in the δ rhythm, there is a significant difference in the channel AF3 (the p value in the hypothesis test is: p = 0.024).
请参阅图10,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的θ的HHT边际谱熵的差异性示意图。Please refer to FIG. 10 , which is a schematic diagram showing the difference of HHT marginal spectral entropy of θ of 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
从图10中可以看出,在θ节律中,通道AF4中有显著性差异,(假设检验中的P值为:p=0.01)。As can be seen from Fig. 10, in the θ rhythm, there is a significant difference in the channel AF4 (the P value in the hypothesis test is: p = 0.01).
请参阅图11,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的α的HHT边际谱熵的差异性示意图。Please refer to FIG. 11 , which is a schematic diagram showing the difference of the HHT marginal spectral entropy of α in 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
从图11中可以看出,在α节律中,通道FC5中有显著性差异(p=0.049)。As can be seen from Figure 11, there is a significant difference in channel FC5 in the alpha rhythm (p = 0.049).
请参阅图12,为本发明一实施例提供的腰椎间盘突出症患者推拿前后14个通道的β的HHT边际谱熵的差异性示意图。Please refer to FIG. 12 , which is a schematic diagram showing the difference of the HHT marginal spectral entropy of β in 14 channels before and after massage in patients with lumbar disc herniation according to an embodiment of the present invention.
请参阅图12,在β节律中,通道F3,P7,O1,P8,FC6,F8有显著性差异,(假设检验中的p值分别为:p=0.047,p=0.003,p=0.042,p=0.008,p=0.007,p=0.01)。Referring to Figure 12, in the β rhythm, there are significant differences in the channels F3, P7, O1, P8, FC6, and F8. (The p values in the hypothesis test are: p=0.047, p=0.003, p=0.042, p =0.008, p=0.007, p=0.01).
步骤S150:分析腰椎间盘突出症患者推拿前后有显著性差异的通道或节 律与VAS疼痛等级的相关性。Step S150: analyzing the channel or section of the lumbar disc herniation patient with significant difference before and after massage Correlation between the law and the VAS pain level.
优选地,分析推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性,包括将腰椎间盘突出症患者推拿前后出现显著性差异的通道或节律的值做差,然后与VAS疼痛等级作相关性分析。Preferably, the correlation between the channel or rhythm with significant difference before and after the massage and the VAS pain level is analyzed, including the value of the channel or rhythm of the significant difference before and after the massage of the lumbar disc herniation patient, and then with the VAS pain level Correlation analysis.
具体地,将上述步骤S140中将腰椎间盘突出症患者推拿前后出现显著性差异的通道或节律做差(推拿前的值-推拿后的值),然后与VAS疼痛等级作相关性分析。Specifically, in the above step S140, the channel or rhythm in which the significant difference is present before and after the massage of the lumbar disc herniation patient is poor (the value before the massage - the value after the massage), and then the correlation analysis is performed with the VAS pain level.
请参阅表1是本发明实施例提供的推拿前后O2通道HHT边际谱熵差值与VAS的相关性检测结果、表2是本发明实施例提供的推拿前后P8通道HHT边际谱熵差值与VAS的相关性检测结果、表3是本发明实施例提供的推拿前后AF3通道的δ节律HHT边际谱熵差值与VAS的相关性检测果,从表1、2及3中可以看出,O2和P8通道的HHT边际谱熵以及AF3通道的δ节律的HHT边际谱熵与VAS疼痛等级具有显著相关性(相关性系数分别为:r=-0.444,r=-0.397,r=0.420假设检验中的P值分别为:p=0.023、p=0.045、p=0.033)Please refer to Table 1 for the correlation detection result of the HHT marginal spectral entropy difference and VAS before and after the massage provided by the embodiment of the present invention, and FIG. 2 is the HHT marginal spectral entropy difference and VAS of the P8 channel before and after the massage according to the embodiment of the present invention. The correlation detection result, Table 3 is the correlation detection result of the δ rhythm HHT marginal spectral entropy difference and VAS of the AF3 channel before and after the massage provided by the embodiment of the present invention, as can be seen from Tables 1, 2 and 3, O2 and The HHT marginal spectral entropy of the P8 channel and the HHT marginal spectral entropy of the δ rhythm of the AF3 channel are significantly correlated with the VAS pain level (correlation coefficients are: r=-0.444, r=-0.397, r=0.420 hypothesis test) The P values are: p=0.023, p=0.045, p=0.033)
Figure PCTCN2017077701-appb-000003
Figure PCTCN2017077701-appb-000003
Figure PCTCN2017077701-appb-000004
Figure PCTCN2017077701-appb-000004
请参阅图13,为本发明一实施例提供的腰椎间盘突出症患者推拿效果的评估系统200的结构示意图,包括:采集模块210、预处理模块220、特征提取模块230、分析模块240及比较模块250。其中:FIG. 13 is a schematic structural diagram of an evaluation system 200 for a massage effect of a lumbar disc herniation patient according to an embodiment of the present invention, including: an acquisition module 210, a preprocessing module 220, a feature extraction module 230, an analysis module 240, and a comparison module. 250. among them:
采集模块210、用于采集腰椎间盘突出症患者推拿前后脑电数据;预处理模块220用于对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理;特征提取模块230用于提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值;分析模块240用于将提取的腰椎间盘突出症患者推拿前后的特征值 进行统计学分析,分析腰椎间盘突出症患者推拿前后脑电信号的变化,找出差异的通道或节律;及比较模块150用于分析腰椎间盘突出症患者推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性。The acquisition module 210 is configured to collect brain electrical data before and after massage of the lumbar disc herniation patient; the pre-processing module 220 is configured to pre-process the acquired electroencephalogram data of the lumbar disc herniation patient before and after massage; and the feature extraction module 230 is used for extracting the pre-processing The characteristic value of the EEG data before and after massage in the patient with lumbar disc herniation; the analysis module 240 is used for extracting the characteristic values before and after the massage of the lumbar disc herniation patient Statistical analysis was performed to analyze changes in EEG signals before and after massage in patients with lumbar disc herniation, to find out the channel or rhythm of difference; and Comparison Module 150 was used to analyze the channel or rhythm of significant differences between patients with lumbar disc herniation before and after massage. Correlation of VAS pain levels.
上述腰椎间盘突出症患者推拿效果的评估系统200详细技术方案在本发明提供的腰椎间盘突出症患者推拿效果的评估方法100中已有详细描述,这里不再赘述。The detailed technical solution of the evaluation system 200 for the massage effect of the lumbar disc herniation patient has been described in detail in the method 100 for evaluating the massage effect of the lumbar disc herniation patient provided by the present invention, and will not be described herein.
本发明提供的腰椎间盘突出症患者推拿效果的评估方法及系统,对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理,提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值,将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,并分析推拿前后脑电信号的变化,找出差异的通道或节律,分析腰椎间盘突出症患者推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性,本发明提供的腰椎间盘突出症患者推拿效果的评估方法及系统通过对采集的脑电数据进行一系列数据处理得到特征值,进行统计学分析,找出腰椎间盘突出症患者推拿前后的差异性,进而对推拿效果进行初步的康复训练评估,与传统的影像学评估推拿效果相比,它具有无创,方便在任何场所测量,以及可以反映出影像学不能反映的运动异常特征的优点,与传统的评分表评估推拿效果相比具有客观准确的优点。The invention provides a method and a system for evaluating the massage effect of lumbar disc herniation patients, and preprocesses the electroencephalogram data of the patients with lumbar disc herniation before and after the extraction, and extracts the electroencephalogram data of the pre-treated lumbar disc herniation patients before and after massage. The eigenvalues were used to statistically analyze the eigenvalues of the patients with lumbar disc herniation before and after massage, and to analyze the changes of EEG signals before and after massage, to find out the different channels or rhythms, and to analyze the significantity of patients with lumbar disc herniation before and after massage. The correlation between the channel or rhythm of the difference and the VAS pain level, the method and system for evaluating the massage effect of the lumbar disc herniation patient provided by the present invention obtains characteristic values by performing a series of data processing on the collected EEG data, and performs statistical analysis. Find out the difference between before and after massage in patients with lumbar disc herniation, and then carry out preliminary rehabilitation training evaluation on the massage effect. Compared with the traditional imaging evaluation, it has non-invasive, convenient measurement in any place, and can reflect the image. The advantages of motion anomalies that cannot be reflected, Traditional score sheet to evaluate the effect of massage has advantages over objective and accurate.
以上所述实施例的各技术特征可以进行任意的组合,为使描述简洁,未对上述实施例中的各个技术特征所有可能的组合都进行描述,然而,只要这些技术特征的组合不存在矛盾,都应当认为是本说明书记载的范围。The technical features of the above-described embodiments may be arbitrarily combined. For the sake of brevity of description, all possible combinations of the technical features in the above embodiments are not described. However, as long as there is no contradiction between the combinations of these technical features, All should be considered as the scope of this manual.
以上所述实施例仅表达了本发明的几种实施方式,其描述较为具体和详细,但并不能因此而理解为对发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本发明构思的前提下,还可以做出若干变形和改进,这些都属于本发明的保护范围。因此,本发明专利的保护范围应以所附权利要求为准。 The above-described embodiments are merely illustrative of several embodiments of the present invention, and the description thereof is more specific and detailed, but is not to be construed as limiting the scope of the invention. It should be noted that a number of variations and modifications may be made by those skilled in the art without departing from the spirit and scope of the invention. Therefore, the scope of the invention should be determined by the appended claims.

Claims (10)

  1. 一种腰椎间盘突出症患者推拿效果的评估方法,其特征在于,包括下述步骤:A method for evaluating the effect of massage of a patient with lumbar disc herniation, comprising the steps of:
    采集腰椎间盘突出症患者推拿前后脑电数据;Collecting EEG data before and after massage in patients with lumbar disc herniation;
    对所述腰椎间盘突出症患者推拿前后脑电数据进行预处理;Pre-processing the electroencephalogram data of the patients with lumbar disc herniation before and after massage;
    提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值;Extracting the characteristic values of the EEG data before and after manipulation of the pre-treated lumbar disc herniation patients;
    将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,分析推拿前后脑电信号的变化,找出差异性显著的通道或节律;及The characteristic values of the extracted lumbar disc herniation patients before and after massage were statistically analyzed, and the changes of EEG signals before and after massage were analyzed to find out the significant channel or rhythm;
    分析腰椎间盘突出症患者推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性。To analyze the correlation between the channel or rhythm of patients with lumbar disc herniation before and after massage and the level of VAS pain.
  2. 根据权利要求1所述的腰椎间盘突出症患者推拿效果的评估方法,其特征在于,在采集腰椎间盘突出症患者推拿前后脑电数据的步骤中,采集腰椎间盘突出症患者脑电数据的仪器为EMOTIV EPOC脑电采集仪。The method for evaluating the effect of massage of a patient with lumbar disc herniation according to claim 1, wherein in the step of collecting brain electrical data before and after massage of the patient with lumbar disc herniation, the instrument for collecting brain electrical data of the patient with lumbar disc herniation is EMOTIV EPOC EEG Collector.
  3. 根据权利要求1所述的腰椎间盘突出症患者推拿效果的评估方法,其特征在于,所述EMOTIV EPOC脑电采集仪的电极放置采用国际10/20系统标准,所述电极同时记录14导电极EEG数据,14导电极的14个通道分别为AF3,F7,F3,FC5,T7,P7,O1,O2,P8,T8,FC6,F4,F8,AF4,所述电极为Ag/AGCI电极,所述EMOTIV EPOC脑电采集仪的脑电采样频率为128Hz,所述腰椎间盘突出症患者脑电数据的波段包括1~3Hz的δ波、4~7Hz的θ波、8~13Hz的α波、14~30Hz的β波。The method for evaluating the massage effect of a patient with lumbar disc herniation according to claim 1, wherein the electrode placement of the EMOTIV EPOC brain electricity collecting instrument adopts the international 10/20 system standard, and the electrode simultaneously records 14 conductive electrode EEG. Data, the 14 channels of the 14-lead electrode are AF3, F7, F3, FC5, T7, P7, O1, O2, P8, T8, FC6, F4, F8, AF4, and the electrodes are Ag/AGCI electrodes, The EEG sampling frequency of the EMOTIV EPOC EEG is 128 Hz. The band of EEG data of patients with lumbar disc herniation includes δ wave of 1~3Hz, θ wave of 4~7Hz, α wave of 8~13Hz, 14~ 30 Hz beta wave.
  4. 根据权利要求3所述的腰椎间盘突出症患者推拿效果的评估方法,其特征在于,在对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理的步骤 中,所述预处理为去噪处理。The method for evaluating the effect of massage of a patient with lumbar disc herniation according to claim 3, wherein the step of pretreating the electroencephalogram data before and after the manipulation of the collected lumbar disc herniation patient The preprocessing is a denoising process.
  5. 根据权利要求4所述的腰椎间盘突出症患者推拿效果的评估方法,其特征在于,所述去噪处理的方法为小波包变换。The method for evaluating the effect of massage of a patient with lumbar disc herniation according to claim 4, wherein the method of denoising processing is wavelet packet transform.
  6. 根据权利要求5所述的腰椎间盘突出症患者推拿效果的评估方法,其特征在于,经小波包变换后的腰椎间盘突出症患者推拿前后脑电数据按照二进制格雷码排列的,其中各个频段对应的节点情况如下:δ波对应小波节点为(6,1)和(6,3)之和;θ波对应小波节点为(6,4)、(6,6)、(6,7)之和;α波对应小波节点为(6,8)、(6,12)、(6,13)、(6,14)、(6,15)之和;β波对应小波节点为(6,10)、(6,11)、(6,16)、(6,17)、(6,18)(6,19)、(6,22)、(6,23)、(6,24)、(6,25)、(6,26)、(6,27)、(6,28)、(6,29)、(6,30)、(6,31)之和。The method for evaluating the massage effect of a patient with lumbar disc herniation according to claim 5, wherein the brain electrical data before and after massage of the lumbar disc herniation after wavelet packet transformation is arranged according to a binary Gray code, wherein each frequency band corresponds to The node conditions are as follows: the delta wave corresponds to the sum of the (6, 1) and (6, 3) wavelet nodes; the θ wave corresponds to the sum of the (6, 4), (6, 6), (6, 7) wavelet nodes; The α wave corresponds to the sum of the wavelet nodes (6, 8), (6, 12), (6, 13), (6, 14), (6, 15); the β wave corresponds to the wavelet node (6, 10), (6,11), (6,16), (6,17), (6,18)(6,19), (6,22), (6,23), (6,24), (6, 25), (6, 26), (6, 27), (6, 28), (6, 29), (6, 30), (6, 31).
  7. 根据权利要求6所述的腰椎间盘突出症患者推拿效果的评估方法,其特征在于,在提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值的步骤中,所述特征值包括腰椎间盘突出症患者推拿前后14个通道的近似熵和HHT边际谱熵特征值及14个通道的4个节律的近似熵和HHT边际谱熵特征值,所述4个节律为δ、θ、α和β。The method for evaluating the effect of massage of a patient with lumbar disc herniation according to claim 6, wherein in the step of extracting characteristic values of electroencephalogram data before and after manipulation of the pre-treated lumbar disc herniation patient, the characteristic value includes Approximate entropy and HHT marginal spectral entropy eigenvalues of 14 channels before and after massage, and approximate entropy and HHT marginal spectral entropy eigenvalues of 14 channels of lumbar disc herniation, the four rhythms are δ, θ, α And β.
  8. 根据权利要求7所述的腰椎间盘突出症患者推拿效果的评估方法,其特征在于,其中,将提取的推拿前后腰椎间盘突出症患者的特征值进行统计学分析,分析推拿前后脑电信号的变化,找出差异的通道或节律,包括下述步骤:The method for evaluating the effect of massage of a patient with lumbar disc herniation according to claim 7, wherein the characteristic values of the patients with lumbar disc herniation before and after the extraction are statistically analyzed, and the changes of the brain electrical signals before and after the massage are analyzed. To find the channel or rhythm of the difference, including the following steps:
    分析腰椎间盘突出症患者推拿前后14个通道的4个节律δ、θ、α和β的近似熵的差异性;To analyze the difference in the approximate entropy of the four rhythms δ, θ, α and β of 14 channels before and after massage in patients with lumbar disc herniation;
    分析腰椎间盘突出症患者推拿前后14个通道的HHT边际谱熵的差异性;To analyze the difference of HHT marginal spectral entropy in 14 channels before and after massage in patients with lumbar disc herniation;
    分析腰椎间盘突出症患者推拿前后14个通道的4个节律δ、θ、α和β的近似熵的差异性; To analyze the difference in the approximate entropy of the four rhythms δ, θ, α and β of 14 channels before and after massage in patients with lumbar disc herniation;
    分析腰椎间盘突出症患者推拿前后14个通道的4个节律δ、θ、α和β的HHT边际谱熵的差异性。The differences in HHT marginal spectral entropy of four rhythms δ, θ, α and β in 14 channels before and after massage were analyzed in patients with lumbar disc herniation.
  9. 根据权利要求8所述的腰椎间盘突出症患者推拿效果的评估方法,其特征在于,其中,分析推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性,包括将腰椎间盘突出症患者推拿前后出现差异的通道或节律的值做差,然后与VAS疼痛等级作相关性分析。The method for evaluating the effect of massage of a patient with lumbar disc herniation according to claim 8, wherein a correlation between a channel or a rhythm having a significant difference before and after the massage and a VAS pain level, including a patient with lumbar disc herniation, is analyzed. The values of the channels or rhythms that differed before and after the massage were poor, and then correlated with the VAS pain level.
  10. 一种腰椎间盘突出症患者推拿效果的评估系统,其特征在于,包括:An evaluation system for the effect of massage of lumbar disc herniation patients, comprising:
    采集模块,用于采集腰椎间盘突出症患者推拿前后脑电数据;An acquisition module for collecting brain electrical data before and after massage in patients with lumbar disc herniation;
    预处理模块,用于对采集的腰椎间盘突出症患者推拿前后脑电数据进行预处理;a pre-processing module for pre-processing the brain electrical data before and after massage of the collected lumbar disc herniation patients;
    特征提取模块,用于提取预处理后的腰椎间盘突出症患者推拿前后脑电数据的特征值;a feature extraction module, configured to extract characteristic values of brain electrical data before and after manipulation of the pre-treated lumbar disc herniation patient;
    分析模块,用于将提取的腰椎间盘突出症患者推拿前后的特征值进行统计学分析,分析腰椎间盘突出症患者推拿前后脑电信号的变化,找出有差异性显著的通道或节律;及The analysis module is used for statistical analysis of the characteristic values of the extracted lumbar disc herniation patients before and after massage, and analyzes the changes of the EEG signals before and after massage in patients with lumbar disc herniation, and finds the channel or rhythm with significant difference;
    比较模块,用于分析腰椎间盘突出症患者推拿前后有显著性差异的通道或节律与VAS疼痛等级的相关性。 A comparison module was used to analyze the association of a channel or rhythm with a significant difference in VAS pain levels before and after manipulation in patients with lumbar disc herniation.
PCT/CN2017/077701 2017-03-22 2017-03-22 Method and system for assessing effectiveness of tui na on lumbar disc herniation WO2018170792A1 (en)

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